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Aspects of Mono- and Multiple Dominant Follicle Development in the Human Ovary.
Thesis Erasmus University, Rotterdam, The Netherlands
The work presented in this thesis was performed at the Division of Reproductive Medicine (Head:
Prof.dr. B.C.J.M. Fauser), department of Obstetrics and Gynaecology, Erasmus MC, Rotterdam, The
Netherlands.
ISBN: 90-8559-039-6
Cover design: Femke Hohmann and Optima Grafische Communicatie, Rotterdam 2005
Cover illustration: Vincent van Gogh (1853-1890), De Sterrennacht, Saint Rémy 1889
Printed: Optima Grafische Communicatie, Rotterdam
Copyright © Femke Pauline Hohmann, 2005
No part of this thesis may be reproduced in any form or by any means, by print, photocopy, microfilm
or any other means and without permission of the author.
Niets uit deze uitgave mag worden verveelvoudigd en/of openbaar gemaakt door middel van druk,
fotokopie, microfilm of welke andere wijze dan ook zonder voorafgaande schriftelijke toestemming
van de schrijver.
Parts of this PhD thesis have been published previously and have been reproduced with permission of
the publishers: © European Society of Human Reproduction and Embryology. Reproduced by permission
of Oxford University Press/Human Reproduction (Hohmann, F.P., Laven, J.S.E., de Jong F.H.,
Eijkemans, M.J.C., and Fauser, B.C.J.M. (2001) Low-dose exogenous FSH during the early, mid or
late follicular phase can induce multiple dominant follicle development. Hum. Reprod., 16, 846-854);
© The Endocrine Society (Hohmann, F.P., Macklon, N.S., and Fauser, B.C.J.M. (2003) A randomized
comparison of two ovarian stimulation protocols with gonadotropin-releasing hormone (GnRH) antagonist
cotreatment for in vitro fertilization commencing recombinant follicle-stimulating hormone
on cycle day 2 or 5 with the standard long GnRH agonist protocol. J. Clin. Endocrin. Metab., 88, 166-
173); © European Federation of Endocrine Societies. Reproduced with permission of BioScientifica/
European Journal of Endocrinology (Hohmann, F.P., Laven, J.S.E., de Jong F.H., and Fauser, B.C.J.M.
(2005) Relationship between inhibin A and B, oestradiol and follicle growth dynamics during ovarian
stimulation in normo-ovulatory women. Eur. J. Endocrinol., 152, 395–401); © European Federation of
Endocrine Societies. Reproduced with permission of BioScientifica/European Journal of Endocrinology
(van Santbrink, E.J.P., Hohmann, F.P., Eijkemans, M.J.C., Laven, J.S.E., and Fauser, B.C.J.M. (2005)
Does metformin modify ovarian responsiveness during exogenous follicle-stimulating hormone ovulation
induction in normogonadotrophic anovulation? A placebo controlled double blind assessment.
Eur. J. Endocrinol., 152, 611–617).
S.B.O.H. & Serono Benelux BV & Hitachi Medical Systems BV & Ferring BV & Organon Nederland
BV & Medical Dynamics & Schering Nederland BV & Cook Nederland BV & Memidis Pharma BV
are gratefully acknowledged for their financial support in the publication of this thesis.