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Chapter 2<br />
36<br />
FSH (IU/l)<br />
Oestradiol (pmol/l)<br />
Inhibin B (ng/l)<br />
Inhibin A (ng/l)<br />
Single<br />
dominant follicle development<br />
9<br />
6<br />
3<br />
0<br />
2,000<br />
1,000<br />
0<br />
400<br />
200<br />
0<br />
150<br />
100<br />
50<br />
0<br />
3<br />
5<br />
n = 16<br />
7<br />
9<br />
cycle days<br />
hCG<br />
hCG-1/2<br />
Multiple<br />
dominant follicle development<br />
9<br />
6<br />
3<br />
0<br />
2,000<br />
1,000<br />
150<br />
100<br />
50<br />
CD 3 (n=4 vs n=9) CD 5 (n=3 vs n=10)<br />
0<br />
400<br />
200<br />
0<br />
0<br />
3<br />
5<br />
n = 24<br />
7<br />
9<br />
cycle days<br />
hCG<br />
hCG-1/2<br />
CD 7 (n=9 vs n=5)<br />
Figure 2.4<br />
Figure 2.4 Follicular phase FSH, oestradiol and inhibin B and A concentrations in 40 normo-ovula-<br />
tory women receiving low daily doses of exogenous FSH, starting on either cycle day 3, 5 or 7. The<br />
panels represent the subjects who developed single (left panels) or multiple (right panels) dominant<br />
follicles (≥ 10 mm) on the day of hCG administration. The time scale on the x-axis is divided into cycle<br />
days (day of onset menses = cycle day 1) and days prior to administration of hCG. Data are shown<br />
as the mean values.