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identification of antidiabatic activity strychnos nux-vomica roots

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S. Tripathi et al., IJSID 2011, 1 (3), 30-33<br />

there have been observed a glittering appearance just outside the field <strong>of</strong> distinct vision, and also black and gray<br />

points floating before the eyes.<br />

Other Species in this Family<br />

Strychnos tieute, a clumbing shrub growing in Java, gives a juice termed Upas tieute, said to be used by the<br />

natives as an arrow poison; it produces death by violent convulsions, the heart stopping before respiration. S.<br />

toxifera yields the deadly poison Curare (Woorari or Urari) used by the natives <strong>of</strong> British Guiana. S. ligustrina, the<br />

wood <strong>of</strong> which contains brucine, as does the bark.<br />

S. pseudo is found in the mountains and forests <strong>of</strong> India. It supplies the seeds known as clearing nuts. The<br />

fruit is black, the size <strong>of</strong> a cherry, containing only one seed; fruit and seeds are used medicinally in India and also to<br />

clear muddy water, the seeds being rubbed for a minute inside the vessel and the water then allowed to settle;<br />

their efficiency depending on their albumen and casein contents acting as a fining agent similar to those employed<br />

to clarify wine and beer. S innocua, the fruit and pulp are harmless and are eaten by the natives <strong>of</strong> Egypt and<br />

Senegal. S Ignatii is found in the Philippines, the seeds containing strychnine and brucine, strychnine being present<br />

in greater quantity than in Nux Vomica. A tincture made from the beans is <strong>of</strong>ficial in the British Pharmacopoeia<br />

Codex.<br />

CONCLUSION<br />

Based on the complete study and results, it proves that STRYCHNOS NUX-VOMICA plant root have Anti diabetic<br />

<strong>activity</strong> and other studies were under progress.<br />

REFERENCES<br />

1. Arnold, M.D., Harry L. (1968). Poisonous Plants <strong>of</strong> Hawaii. Tokyo, Japan: Charles E. Tuttle Co. p. 20.<br />

2. David Michael Wood et al. Case report: Survival after deliberate strychnine self-poisoning, with toxicokinetic data. Critical<br />

Care October 2002 Vol 6 No 5<br />

3. Duddukuri GR, Brahmam AN, Rao DN"Suppressive effect <strong>of</strong> <strong>strychnos</strong> <strong>nux</strong>-<strong>vomica</strong> on induction <strong>of</strong> ovalbumin-specific IgE<br />

antibody response in mice." Indian J Biochem Biophys. 2008 Oct;45(5):341-4<br />

4. Lee SM, Kwon JI, Choi YH, Eom HS, Chi GY.,"Induction <strong>of</strong> G2/M arrest and apoptosis by water extract <strong>of</strong> Strychni Semen in<br />

human gastric carcinoma AGS cells." Phytother Res. 2008 Jun;22(6):752-8<br />

5. Akbar S, Khan SA, Masood A, Iqbal M"Use <strong>of</strong> Strychnos <strong>nux</strong>-<strong>vomica</strong> (Azraqi) seeds in Unani system <strong>of</strong> medicine: role <strong>of</strong><br />

detoxification." Afr J Tradit Complement Altern Med. 2010;7(4):286-90<br />

6. Han QB, Li SL, Qiao CF, Song JZ, Cai ZW, Pui-Hay But P, Shaw PC, Xu HX.,"A Simple Method to Identify the Unprocessed<br />

Strychnos Seeds used in Herbal Medicinal Products." Planta Med. 2008 Mar;74(4):458-63<br />

7. H<strong>of</strong>bauer R, Pasching E, Moser D, Frass "Heparin-binding epidermal growth factor expression in KATO-III cells after<br />

Helicobacter pylori stimulation under the influence <strong>of</strong> <strong>strychnos</strong> Nux <strong>vomica</strong> and Calendula <strong>of</strong>ficinalis"., Homeopathy.<br />

2010 Jul;99(3):177-82M<br />

8. Grieve, M.. "Nux Vomica". Botanical.com, a Modern Herbal. 3 Nov 2010.<br />

9. "Strychnos Nux-<strong>vomica</strong>". American Cancer Society. Retrieved 3 Nov 2010.<br />

International Journal <strong>of</strong> Science Innovations and Discoveries, Volume 1, Issue 3, November-December 2011<br />

33

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