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Acino adds blockbuster esomeprazole to its product portfolio

Acino adds blockbuster esomeprazole to its product portfolio

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NEWS RELEASE — PRESSEMITTEILUNG<br />

<strong>Acino</strong> <strong>adds</strong> <strong>blockbuster</strong> <strong>esomeprazole</strong> <strong>to</strong> <strong>its</strong> <strong>product</strong><br />

<strong>portfolio</strong><br />

Basle, April 2, 2012, 07.00 hrs — Shortly after having acquired Cephalon/Mepha’s international<br />

business in the Middle East, Africa, Asia and Latin America, <strong>Acino</strong> continues<br />

<strong>its</strong> expansion in global emerging markets under <strong>its</strong> «<strong>Acino</strong> Switzerland» brand by successfully<br />

in-licensing the <strong>blockbuster</strong> drug <strong>esomeprazole</strong>. The licensing agreements include<br />

<strong>esomeprazole</strong> 20 mg and 40 mg MUPS (Multiple Unit Particulate Systems) tablets,<br />

and <strong>esomeprazole</strong> 40 mg lyophilized powder for injection. The <strong>esomeprazole</strong> MUPS tablets<br />

are being produced at <strong>Acino</strong>’s manufacturing site in Liesberg (Can<strong>to</strong>n Baselland,<br />

Switzerland).<br />

Esomeprazole (original <strong>product</strong> Nexium® from AstraZeneca), a pro<strong>to</strong>n pump inhibi<strong>to</strong>r<br />

(PPI), is being used in the treatment of indications such as dyspepsia, peptic ulcer disease<br />

(PUD), gastro-esophageal reflux disease (GORD/GERD) and Zollinger-Ellison syndrome.<br />

The <strong>product</strong> (oral and parenteral presentations) generated worldwide annual<br />

sales of over USD 8.7 billion (MAT 06/2011) and is among the <strong>to</strong>p five drugs in several of<br />

<strong>Acino</strong>’s target markets.<br />

Through this in-licensing agreement <strong>Acino</strong> will further strengthen <strong>its</strong> position in the gastrointestinal<br />

therapeutic area. The company is anticipating a good match with <strong>its</strong> strong franchise<br />

with the branded <strong>product</strong> Gasec® (omeprazole), which Mepha built up over the<br />

years in different international markets. In addition, <strong>Acino</strong> successfully completed the inlicensing<br />

of another PPI, pan<strong>to</strong>prazole 40 mg, for injection.<br />

Dr. Manuel Heim, Head of Global Marketing, said: “We consider this an excellent fit <strong>to</strong><br />

support our own-brand marketing strategy of providing Swiss quality <strong>product</strong>s with advanced<br />

and refined application technologies such as MUPS, ensuring effective relief <strong>to</strong><br />

patients. We expect <strong>to</strong> add more <strong>product</strong>s <strong>to</strong> our existing <strong>portfolio</strong> with a focus on the<br />

therapeutic areas pain, oncology, urology, antiinfectives, cardiovascular disease, gastrointestinal<br />

disorders, and others.<br />

Ruud van Anraat, Chief Commercial Officer, added: “ <strong>Acino</strong> - with <strong>its</strong> Swiss base, international<br />

market presence, and high quality standards - will be ideally placed <strong>to</strong> capitalize on<br />

the potential of these <strong>product</strong>s in up and coming markets. It underscores our dedication<br />

and focus, making «<strong>Acino</strong> Switzerland» a preferred partner in emerging markets with the<br />

aim <strong>to</strong> make quality medicine accessible for the benefit of the patient.”<br />

<strong>Acino</strong> Holding Ltd.<br />

Erlenstrasse 1<br />

CH-4058 Basle<br />

Phone +41 61 338 60 00<br />

Fax +41 61 338 60 80<br />

www.acino-pharma.com


<strong>Acino</strong> – Delivering Health<br />

<strong>Acino</strong> (SIX: ACIN), a Swiss-based pharmaceutical company, develops, manufactures and internationally<br />

markets well-proven and innovative pharmaceuticals in novel drug delivery forms. <strong>Acino</strong> is a<br />

leader in advanced drug delivery technologies with a focus on modified release oral forms, oral<br />

dispersible forms, transdermal systems and extended release parenterals, for which it also holds<br />

patents. As a partner of pharmaceutical companies worldwide, <strong>Acino</strong> supplies finished in-house<br />

developed <strong>product</strong>s and/or provides cus<strong>to</strong>mized one-s<strong>to</strong>p solutions from <strong>product</strong> development and<br />

registration <strong>to</strong> contract manufacturing, packaging and logistics. Under the brand “<strong>Acino</strong> Switzerland”,<br />

<strong>Acino</strong> markets Swiss-quality medicines in up and coming economies. The <strong>Acino</strong> Group is<br />

headquartered in Basle, at present has about 870 employees (including staff members from<br />

Mepha) and generated annual revenues of EUR 135 million in 2011.<br />

Contact Calendar<br />

Peter Burema<br />

CEO <strong>Acino</strong> Group<br />

Phone +41 61 338 60 00<br />

info@acino-pharma.com<br />

www.acino-pharma.com<br />

Page 2 / 22<br />

5.4.2012 General Meeting of Shareholders<br />

11.4.2012 Dividend ex-date<br />

13.4.2012 Dividend record date<br />

16.4.2012 Dividend payment date<br />

2.8.2012 Half-year report as of June 30, 2012<br />

<strong>Acino</strong> Holding Ltd.<br />

Erlenstrasse 1<br />

CH-4058 Basle<br />

Phone +41 61 338 60 00<br />

Fax +41 61 338 60 80<br />

www.acino-pharma.com

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