JSEI CLINICAL RESEARCH SEMINAR - Jules Stein Eye Institute

Thomas H. Pettit Lecture
James P. Dunn, Jr., MD
Bradley R. Straatsma
Lecture
Paul S. Bernstein, MD, PhD
35th Jules Stein Lecture
Robert N. Weinreb, MD
Friday & Saturday
May 21 & 22 2004
Jules Stein Eye Institute
2 0 0 4
J S E I
CLINICAL
AND
RESEARCH
S E M I N A R
Los Angeles, CA 90095-7000 U.S.A.
100 Stein Plaza, UCLA
Box 957000
David Geffen School of Medicine
at UCLA
First Class Mail
US Postage
PAID
UCLA
Jules Stein Eye Institute

J S E I
C L I N I C A L
AND
RESEARCH
S E M I N A R
2 0 0 4
Jules Stein Eye Institute
UCLA
D e p a r t m e n t o f
Ophthalmology Association
Meeting and Reception
May 21 & 22 2004
RPB Auditorium
35th Jules Stein Lecture
Robert N. Weinreb, MD
Bradley R. Straatsma Lecture
Paul S. Bernstein, MD, PhD
Thomas H. Pettit Lecture
James P. Dunn, Jr., MD

Join us to revisit the Institute, renew acquaintances with
colleagues, and learn about research being performed by
residents, fellows, and full-time and clinical faculty
M E E T I N G H I G H L I G H T S
35th Jules Stein Lecture
“Changing the Paradigm for Diagnosing Glaucoma”
Presented by Robert N. Weinreb, MD
Professor of Ophthalmology
University of California, San Diego School of Medicine
Bradley R. Straatsma Lecture
“The Biochemisrty and Biophysics of
Nutritional Interventions Against Macular Degeneration:
New Insights into an Old Age Disease”
Presented by Paul S. Bernstein, MD, PhD
Associate Professor of Ophthalmology
University of Utah School of Medicine
Thomas H. Pettit Lecture
“Non-Infectious Peripheral Ulcerative Keratitis”
Presented by James P. Dunn, Jr., MD
Associate Professor of Ophthalmology
Johns Hopkins University School of Medicine
Guest Speakers
Dimitri T. Azar, MD
Professor of Ophthalmology
Harvard Medical School
Sadeer B. Hannush, MD
Assistant Professor of Ophthalmology
Jefferson Medical College
R. Doyle Stulting, MD, PhD
Professor of Ophthalmology
Emory University School of Medicine
Senior Honor Award
Presented by the UCLA Department of Ophthalmology to senior
faculty members who have provided outstanding service to the
department for over 25 years.
2004 Senior Honor Award
Richard H. Yook, MD
Faculty Teaching Award
Presented by the senior resident class to a faculty member
in recognition of an outstanding job as teacher and mentor.
2004 Faculty Teaching Award
Simon K. Law, MD, PharmD

Jules Stein Eye Institute
Clinical and Research Seminar Meeting Coordinators:
Anthony C. Arnold, MD, Chair
Robert Alan Goldberg, MD
Gary N. Holland, MD
Bartly J. Mondino, MD
Xianjie Yang, PhD
Department of Ophthalmology, Jules Stein Eye Institute
Chairman and Director, Bartly J. Mondino, MD
UCLA Department of Ophthalmology Association
President, Peter Cornell, MD
UCLA Department of Ophthalmology Residency Program
Director, Anthony C. Arnold, M.D.
Course Description:
The newly organized Jules Stein Eye Institute Clinical and Research
Seminar will provide ophthalmologists and vision scientists with the
opportunity to discuss and share experiences, review relevant literature,
and synthesize this information into a comprehensive approach to
evaluation, management, and treatment of ophthalmic diseases. In
addition to formal lectures there will be ample opportunity for questions
and answers and discussion between faculty and attendees.
Goals & Objectives:
■ Provide didactic presentations, videos and panel discussions on a
variety of topics relevant to clinical practice
■ Present and discuss the future of ophthalmic disorder diagnosis and
treatment, as well as outcomes
■ Provide participants with understanding of new surgical techniques
and contemporary treatment of ophthalmic disorders
■ Present indications and standards in the medical and surgical
management of ophthalmic diseases
■ Provide insight into current research being conducted at the Institute
Target Audience:
Ophthalmologists and vision scientists

Friday, May 21, 2004
8:00 am Welcome
Bartly J. Mondino, MD
Cornea
8:10 am Introduction to
Cornea Mini-Symposium
Gary N. Holland, MD
8:15 am Session I:
Applications of Genetic
Analysis to Corneal Practice
Anthony J. Aldave, MD
8:30 am Corneal Dystrophies
Redefined: A Molecular
Genetics-Based
Classification System
Danny Lin, MD
8:40 am Cloning the Gene for
Posterior Polymorphous
Corneal Dystrophy
Alexandre Principe, MD
8:50 am Molecular Basis of Corneal
Clarity and Avascularity
After Refractive Surgery
Dimitri T. Azar, MD
9:10 am Advances in
Keratoprosthesis Surgery
Sadeer B. Hannush, MD
9:30 am Break
J u l e s S t e i n E y e I n s t i t u t e
10:00 am Corneal Ectasia After LASIK
R. Doyle Stulting, MD, PhD
10:20 am Session II:
Refractive Surgery
Roundtable
D. Rex Hamilton, MD, MS
MODERATOR
Anthony J. Aldave, MD
Dimitri T. Azar, MD
Paul B. Donzis, MD
Paul J. Dougherty, MD
Sadeer B. Hannush, MD
Robert K. Maloney, MD
Ronald E. Smith, MD
R. Doyle Stulting, MD
11:15am Session III:
Penetrating Keratoplasty
and Glaucoma
Gary N. Holland, MD
MODERATOR
11:20am Outcomes Associated with
Sequential Ahmed Drainage
Device Placement and
Penetrating Keratoplasty
Bruce E. Wietharn, MD
11:30am Discussion Session:
Anthony J. Aldave, MD
Michelle Banks, MD
Joseph Caprioli, MD
Anne L. Coleman, MD, PhD
JoAnn A. Giaconi, MD
Bartly J. Mondino, MD
11:55 am Introduction of
Thomas H. Pettit Lecturer
Gary N. Holland, MD
12:00pm Thomas H. Pettit Lecture:
Non-Infectious Peripheral
Ulcerative Keratitis
James P. Dunn, Jr., MD
12:30pm Lunch
Pediatric
Ophthalmology
1:30 pm Peripheral Neuroanatomy
of Strabismus
Joseph L. Demer, MD, PhD
1:40 pm An Approach to Reduce
Childhood Blindness
Sherwin J. Isenberg, MD
1:50 pm Short Prism Adaptation
Test for Esotropia
Federico Velez, MD
2:00 pm Past, Present, and Future
of EOM Pulley Surgery
Robert Clark, MD
2:10 pm MRI in CPEO Patients
Carolina Ortube, MD
2:20 pm Divergence Paresis
in Adults
Arthur L. Rosenbaum, MD
Glaucoma
2:30 pm Societal Relevance
of Glaucoma
Anne L. Coleman, MD, PhD
2:45 pm Identifying Early Glaucoma
with Optical Coherence
Tomography
Dana Tannenbaum, MD
2:55 pm Evaluation of
Disc Asymmetry
JoAnn Giaconi, MD
3:05 pm Break
3:20 pm IOP Fluctuation is an
Important Risk Factor for
Progression of Glaucoma
Joseph Caprioli, MD

C l i n i c a l & R e s e a r c h S e m i n a r
3:35 pm Glaucomatous Visual
Field Progression:
To Detect or To Predict
Kouros Nouri-Mahdavi, MD
3:45 pm Silicone versus
Polypropylene Tube Shunt
Simon Law, MD, Pharm D
4:00 pm Outcome of Suture Lysis
after Trabeculectomy
Satvinder Gujral, MD
4:10 pm Activation of Anti-Apoptotic
Heat Shock Protein in
Glaucomatous Retinas
Natik Piriev, PhD
4:25 pm Panel Discussion
4:45 pm Introduction of
Jules Stein Lecturer
Bartly J. Mondino, MD
4:50 pm Jules Stein Lecture:
Changing the Paradigm
for Diagnosing Glaucoma
Robert N. Weinreb, MD
5:20 pm Reception
Saturday, May 22, 2004
Vision Science/Retina
8:00 am The Mer Receptor in
Vision and Blindness
Michael Hall, PhD
8:15am * Comparing the Properties
of αA and αB Crystallins
Joseph Horwitz, PhD
8:30am Crystallins
Suraj P. Bhat, PhD
8:45am Basic Science, Safety and
Efficacy, Current Clinical Trials
Steven D. Schwartz, MD
9:00am Establishing an Animal
Model for Bruch’s
Membrane Defect That
Leads to Macular
Degeneration
Hui Sun, PhD
9:15am New Approaches for
Treating Retinal and
Macular Degenerations
in Animal Models
Gabriel Travis, MD
9:30 am Steroids and Macular Disease
Clinical Trials
Anurag Gupta, MD
9:45am * The MET450 Variant in
RPE65 Alters the
Demands on the Visual
Cycle and Slows
Degeneration in a Mouse
Model of Retinal Disease
Steven Nusinowitz, PhD
10:00 am Business Meeting
10:10 am Break
10:30 am G proteins, Ca-2+ and
Retinal Degeneration
Gordon Fain, PhD
10:45am A Potential Role for the
Retinal Pigment Epithelium
in Innate Immunity
Dean Bok, PhD
11:00 am Function of VEGF and its
Receptors in Retinal
Development
Xian-Jie Yang, PhD
11:15am Anti-VEGF Strategies for the
Treatment of Age-Related
Macular Degeneration
Christine R. Gonzales, MD
11:30am * Deletion from the Mouse
Genome of a Transcription
Factor Involved in B-PDE
Gene Expression Provides
a New Animal Model of
Retinal Degeneration
Debora Farber, PhD, DPhhc
11:45 am Introduction of
Bradley R. Straatsma
Lecturer
Dean Bok, PhD
11:55 am Bradley R. Straatsma
Lecture: The Biochemisrty
and Biophysics of Nutritional
Interventions Against
Macular Degeneration:
New Insights into an
Old Age Disease
Paul S. Bernstein, MD, PhD
12:25 pm Awards Ceremony
12:35 pm Lunch
Comprehensive
Ophthalmology
1:45pm Phacodynamics of
Phaco Chop
Barry Seibel, MD
1:55pm Cataract Surgery in
Monocular Patients
Kevin M. Miller, MD

2:05 pm Technology in
Cataract Surgery
Samuel Masket, MD
2:15 pm Primum Non Nocere
Barry A. Weissman, OD, PhD
2:25 pm Birdshot
Retinochoroidopathy:
A Longitudinal Study
Ralph D. Levinson, MD
2:35pm Evaluating Optic Nerve Size
Shaheen Karim, BS
2:45pm Listing’s Law and the
Angular Vestibulo-ocular
Reflex
Benjamin T. Crane, MD, PhD
2:55pm The Linear
Vestibulo-ocular Reflex
Jun-Ru Tian, MD, PhD
3:05 pm Break
* Not eligible for CME credit
M a y 2 1 – 2 2 , 2 0 0 4
Accommodations
W Los Angeles Hotel
The W Los Angeles Hotel is located within walking distance of the Jules Stein Eye
Institute at 930 Hilgard Avenue, Los Angeles, CA 90024, with rates starting at $225 per
night. For reservations call 1.800.877.W.HOTELS and please mention the Jules Stein
Eye Institute.
Hilgard House
Hilgard House is located across the street from the W Los Angeles Hotel at 927 Hilgard
Avenue, Los Angeles, CA 90024, with rates starting at $109 per night. For reservations
call 310.208.3945 and please mention the UCLA Jules Stein Eye Institute.
Directions
Conveniently located within UCLA at the corner of Westwood Boulevard and Le Conte
Avenue, the Jules Stein Eye Institute, 100 Stein Plaza, Los Angeles, 90095 is easily
accessible from all points in Southern California. It is approximately 15 miles from the
Los Angeles International Airport. Parking is available at the Institute for $7 per day.
From the San Diego Freeway (405)
Take Wilshire Boulevard offramp east (toward Westwood Boulevard). Turn left onto
Westwood Boulevard from Wilshire. After crossing Le Conte, turn right onto Stein Plaza.
Parking is located immediately to the right (adjacent to the Doris Stein Eye Research
Center) as you turn onto Stein Plaza.
Airport Shuttle Service Taxicabs
Orbital and Ophthalmic
Plastic Surgery/
Neuro-Ophthalmology
3:20 pm New Concepts in
Patho-physiology of Graves
Orbitopathy, and Implications
for Management
Raymond Douglas, MD
and Terry Smith, MD
3:38pm Current Treatment
Strategies for Optic Nerve
Sheath Meningiomas
Jonathan Kim, MD
3:56 pm Pseudotumor Cerebri:
A Practical Approach to
Diagnosis and Management
Lynn K. Gordon, MD, PhD
4:14 pm Orbital Trauma Update
Glenn March, MD and
John D. McCann, MD, PhD
4:32 pm Questions and Discussion
4:50 pm Adjourn
■ Prime Time 800.262.7433 ■ Beverly Hills Cab Co. 310.273.6611
■ Skycar 310.306.3554 ■ Checker Cab Co. 800.300.5007
■ Super Shuttle 310.532.5999 ■ United Independent 310.278.2500
■ Yellow Cab 310.838.2121
Information
Debbie Sato, Academic Programs
100 Stein Plaza, Rm 3-223 Los Angeles, CA 90095-7000
Telephone 310.825.4617 Fax 310.206.8015 E-Mail sato@jsei.ucla.edu

Registration
Jules Stein Eye Institute
Clinical & Research Seminar, May 21–22, 2004
Enclosed is my remittance (U.S. currency), payable to UC Regents, for the Jules Stein Eye
Institute Clinical and Research Seminar on May 21– 22, 2004.
Name Degree
Specialty
Address
City State Zip
Telephone Fax
E-Mail
Registration Fees (Includes continental breakfast, lunch, reception, and course materials)
■ $115 for practicing ophthalmologists and optometrists (non-refundable)
■ No charge for ophthalmology residents and fellows who submit a letter of verification
from the training program along with registration form.
Make checks payable to UC Regents or pay by credit card (complete form below)
■ Mastercard ■ Visa ■ American Express
Name as it appears on credit card
Account Number Expiration
Signature
Register by May 14, 2004
Academic Programs
100 Stein Plaza, Room 3-223
Los Angeles, CA 90095
310.825.4617 Telephone
310.206.8015 Fax
CME Sponsor: The Office of Continuing Medical Education, David Geffen School of Medicine at UCLA, is
accredited by the Accreditation Council for Continuing Medical Education to sponsor continuing medical education
for physicians.
Accreditation: The Office of Continuing Medical Education, David Geffen School of Medicine at UCLA, designates
this continuing medical education activity for 13.5 Category 1 credits toward the American Medical
Association Physicians Recognition Award.
Each physician should claim only credits that he/she actually spent in the educational activity.
UCLA Conflict of Interest Disclosure: The FDA has issued a concept paper which classifies commercial
support of scientific and educational programs as promotional unless it can be affirmed that the program is
“truly independent” and free of commercial influence. In addition to independence, the FDA requires that
non-promotional, commercially supported education be objective, balanced, and scientifically rigorous. The
policy further states that all potential conflicts of interest of the CME staff and faculty be fully disclosed to
the program’s participants. We, at UCLA, fully endorse the letter and spirit of this concept.
In compliance with this policy, the program audience will have disclosed to them any potential conflict(s) of
interest related to the contents of presentations made by all faculty participating in sponsored or jointly sponsored
programs by the David Geffen School of Medicine at UCLA.