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Morning Report

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Chronic Diarrhea - Differential<br />

Inflammatory (fever, hematochezia,<br />

abd pain)<br />

• Infectious<br />

• IBD<br />

• Radiation enteritis<br />

• Ischemic colitis<br />

• GVHD<br />

Osmotic (decrease w fasting)<br />

• stool osm gap > 50<br />

• Medications (antacids, lactulose,<br />

sorbitol + many more)<br />

• Antibiotic associated (decrease<br />

fermentation of CHO to organic<br />

acids by normal flora, net decrease<br />

H20 absorption)<br />

• Lactose intolerance<br />

Secretory (no change with fasting, normal<br />

stool osm gap)<br />

• Hormonal (neuroendocrine tumors,<br />

thyroid dx, Addison's, hyperPTH, DM)<br />

• Laxative abuse/stimulants<br />

• Colitis (diverticulitis, collagenous, IBD)<br />

Malassimalation (inc. fecal fat, gap>50)<br />

• celiac, tropical sprue<br />

• whipple's dz<br />

• panc insufficiency<br />

• Bacterial overgrowth<br />

• Short bowel syndrome<br />

Motility/Functional<br />

• IBS<br />

• Rheumatologic (scleraderma)

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