Morning Report 11.1.10 g p
Morning Report 11.1.10 g p
Morning Report 11.1.10 g p
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Adenosine Deaminase<br />
• ADA: enzyme marker of cell-mediated immune<br />
response activity to M tuberculosis, includes T-cell and<br />
Macrophages<br />
• Elevated levels both sensitive and specific for TB<br />
• In pericardial fluid, fluid small study with 20 cases:<br />
• Mean level 92, range 35-135 (nml 0-18)<br />
• Sensitivity 100% and Specificity 83.3%, p40<br />
• Sensitivity and Specificity, 88% and 83%<br />
Arroyo M, Soberman JE. Adenosine deaminase in the diagnosis of tuberulous pericardial effusion. Am J Med Sci. 2008 Mar;335(3):227-9.<br />
Tuon FF, et al. ADA and tuberculous pericarditis—a systematic review with meta-analysis. Acta Trop. 2006 Aug; 99(1):67-74.<br />
Marthur PC, et al. Diagnostic Value of ADA Activity in Tubercular Serositis. Indian J Tuberc 2006;53:92-95.
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