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Morning Report 11.1.10 g p

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HIV and TB Co-infection<br />

• TB increases viral replication in HIV<br />

• Lesotho: 4th highest incidence of TB<br />

in the world: 602 cases/100,000 cases/100 000 in<br />

2005<br />

• 88% of f TB TB-infected i f d adults d l HIV HIV+ i in<br />

Lesotho<br />

Coovadia, HM, et al. Childhood human immunodeficiency virus and TB co-infections: reconciling conflicting data. Int J Tuberc Lung Dis 2 (1998), 844-851.<br />

Gray D, et al. Low Rates of Hepatotoxicity in HIV-infected Children on Anti-retroviral Therapy With and Without Isoniazid Prophylaxis.<br />

Journal of Tropical Pediatrics. Epub Aug 26.<br />

Clinical Practice Guidelines for Pediatric HIV Care: Lesotho COE. July 2009 (2.2)

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