Poster - University of Utah - School of Medicine

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Selectivity assays! EMF (mV) 207.00 206.80 206.60 206.40 206.20 206.00 205.80 205.60 205.40 205.20 10 -‐5 10 -‐5 205.00 30 32 34 36 38 40 Time (min) 10 -‐4 10 -‐4 EMF (mV) 206.60 206.40 206.20 206.00 205.80 205.60 205.40 205.20 205.00 204.80 204.60 204.40 S. aureus aptamer E. coli aptamer 100,000 CFU/mL EMF (mV) 203.00 202.80 202.60 202.40 202.20 202.00 201.80 0 2 4 6 8 10 10 -‐5 10 -5 10 -‐4 10 -‐4 201.60 40 45 50 55 60 1,000,000 CFU/mL Time (min) Time (min) Salmonella typhimurium E. coli Salmonella paratyphi Blank CNT Blank CNT
The Way Forward 1. Confirmation in blood! 2. Explore lower limits <strong>of</strong> detection! 3. Optimize and characterize biosensor! 4. Evaluation with clinical samples! 5. Discuss tool with product developers/companies! 6. Explore other pathogens/targets/samples!
Page 1: ! Development of a Rapid Diagnostic
Page 4 and 5: Current Diagnosis: Blood Culture!
Page 6 and 7: STAGE 1: Typhoid Use Case! Sub-Heal
Page 8 and 9: Stage 2: Biosensor for Typhoid! l t
Page 10 and 11: 130 125 120 NaCl (0.1 to 1 M)! 115
Page 14 and 15: Acknowledgements! • Doris Duke Fo
Page 16: References! Baker et al. Searching

Poster - University of Utah - School of Medicine

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