HEPATITIS VIRUSES

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Hepeviridae, Hepevirus genus 33 nm, icosahedral, (ss + RNA, genome: similar to rubella virus (Togaviridae) Hepatitis E virus • Fecal-oral transmission (water!) great epidemics (China, India), heat and acid stable, zoonosis! (pig 1997, dog, chicken, rat), very rarely: transfusion • Latency: 15-60 days • Symptoms as in the case of HAV (mild disease, no chronic disease or chronic carrier state) self-limiting • Europe: sporadic only • Complications: in pregnant woman 25% with high mortality!!! (DIC) Prof. Dr. Éva Ádám D.Sc.
<strong>HEPATITIS</strong> E VIRUS INFECTION: DIAGNOSIS • anti-HEV Ig ELISA Control: for pregnant woman HEIG (antibody) in the endemic areas, vaccine (recombinant Baculovirus, clinical phase 2, USA, Nepal) Prof. Dr. Éva Ádám D.Sc.
Page 1 and 2: Hepatitis A (HAV) Picornaviridae (1
Page 3 and 4: HEPATITIS VIRUSES TRANSMITTED FECAL
Page 5 and 6: Prof. Dr. Éva Ádám D.Sc.
Page 7 and 8: PREVALENCE OF HEPATITIS A VIRUS (AN
Page 9: PREVENTION and CONTROL • Endemic
Page 13 and 14: PARENTERALLY TRANSMITTED HEPATITIS
Page 15 and 16: VIRION: cubical, peplon Dane partic
Page 17 and 18: Adults and elderly children: 90-99%
Page 19 and 20: ACUTE HEPATITIS B VIRUS INFECTION J
Page 21 and 22: SURVIVAL IN CHRONIC HEPATITIS B VIR
Page 23 and 24: CONTROL HBsAg produced by recombina
Page 25 and 26: Prof. Dr. Éva Ádám D.Sc.
Page 27 and 28: HEPATITIS C VIRUS (HCV ( ) FLAVIVIR
Page 29 and 30: • virus previously identified as
Page 31 and 32: OUTCOMES of HCV hepatitis Prof. Dr.
Page 33 and 34: Serologic Pattern of Acute HCV Infe
Page 35 and 36: Diagnosis • anti-HCV Ig (ELISA, W
Page 37 and 38: THERAPY • interferon • ribaviri
Page 39 and 40: HEPATITIS G VÍRUS FLAVIRUS: simila

HEPATITIS VIRUSES

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