Research and treatment timeline: 30+ years of ms milestones | 4
Research and treatment timeline: 30+ years of ms milestones | 4
Research and treatment timeline: 30+ years of ms milestones | 4
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environment as a possible cause <strong>of</strong> MS<br />
Multiple sclerosis is more common in people who live farther from the equator (although<br />
many exceptions exist). Decreased sunlight exposure has been linked to a higher risk <strong>of</strong> MS.<br />
Decreased vitamin D production <strong>and</strong> intake is the main biological mechanism used to explain<br />
the higher risk <strong>of</strong> MS among those less exposed to sun.<br />
A three-year study coordinated by the World Health Organization (WHO) <strong>and</strong> the Multiple Sclerosis<br />
International Federation (MSIF) highlights prevalence <strong>of</strong> MS across the world. Canada has been<br />
identified as being one <strong>of</strong> the countries with the highest prevalence <strong>of</strong> MS in the world.<br />
What’s happening now<br />
Dr. Afsaneh shirani<br />
university <strong>of</strong><br />
British Columbia<br />
Afsaneh Shirani is a recipient<br />
<strong>of</strong> a 2012 MS Society<br />
Postdoctoral Fellowship.<br />
Dr. Shirani’s project<br />
entitled, “Temporal Changes in Disability<br />
Progression <strong>and</strong> Demographics in Multiple<br />
Sclerosis” will investigate if disability<br />
progression has changed over time in<br />
patients with MS in British Columbia. It will<br />
also examine whether there have been<br />
changes in sex ratio (i.e. the number <strong>of</strong><br />
men <strong>and</strong> women with MS), onset age <strong>and</strong><br />
disease course over time in patients with<br />
MS living in British Columbia, Nova Scotia<br />
<strong>and</strong> Manitoba.<br />
“The results <strong>of</strong> this project would contribute<br />
to a better underst<strong>and</strong>ing <strong>of</strong> the natural<br />
course <strong>of</strong> MS <strong>and</strong> may have important<br />
implications for the role <strong>of</strong> environmental<br />
factors in MS,” Shirani says. “This project<br />
will also provide insights for better social,<br />
economic <strong>and</strong> healthcare planning for<br />
those with MS.”<br />
“<br />
The results <strong>of</strong><br />
this project<br />
will contribute<br />
to a better<br />
underst<strong>and</strong>ing<br />
<strong>of</strong> the natural<br />
course <strong>of</strong> MS<br />
<strong>and</strong> may have<br />
important<br />
implications<br />
for the role <strong>of</strong><br />
environmental<br />
factors in MS.<br />
”<br />
<strong>ms</strong> canada Fall/Winter 2012 7