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Research and treatment timeline: 30+ years of ms milestones | 4

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environment as a possible cause <strong>of</strong> MS<br />

Multiple sclerosis is more common in people who live farther from the equator (although<br />

many exceptions exist). Decreased sunlight exposure has been linked to a higher risk <strong>of</strong> MS.<br />

Decreased vitamin D production <strong>and</strong> intake is the main biological mechanism used to explain<br />

the higher risk <strong>of</strong> MS among those less exposed to sun.<br />

A three-year study coordinated by the World Health Organization (WHO) <strong>and</strong> the Multiple Sclerosis<br />

International Federation (MSIF) highlights prevalence <strong>of</strong> MS across the world. Canada has been<br />

identified as being one <strong>of</strong> the countries with the highest prevalence <strong>of</strong> MS in the world.<br />

What’s happening now<br />

Dr. Afsaneh shirani<br />

university <strong>of</strong><br />

British Columbia<br />

Afsaneh Shirani is a recipient<br />

<strong>of</strong> a 2012 MS Society<br />

Postdoctoral Fellowship.<br />

Dr. Shirani’s project<br />

entitled, “Temporal Changes in Disability<br />

Progression <strong>and</strong> Demographics in Multiple<br />

Sclerosis” will investigate if disability<br />

progression has changed over time in<br />

patients with MS in British Columbia. It will<br />

also examine whether there have been<br />

changes in sex ratio (i.e. the number <strong>of</strong><br />

men <strong>and</strong> women with MS), onset age <strong>and</strong><br />

disease course over time in patients with<br />

MS living in British Columbia, Nova Scotia<br />

<strong>and</strong> Manitoba.<br />

“The results <strong>of</strong> this project would contribute<br />

to a better underst<strong>and</strong>ing <strong>of</strong> the natural<br />

course <strong>of</strong> MS <strong>and</strong> may have important<br />

implications for the role <strong>of</strong> environmental<br />

factors in MS,” Shirani says. “This project<br />

will also provide insights for better social,<br />

economic <strong>and</strong> healthcare planning for<br />

those with MS.”<br />

“<br />

The results <strong>of</strong><br />

this project<br />

will contribute<br />

to a better<br />

underst<strong>and</strong>ing<br />

<strong>of</strong> the natural<br />

course <strong>of</strong> MS<br />

<strong>and</strong> may have<br />

important<br />

implications<br />

for the role <strong>of</strong><br />

environmental<br />

factors in MS.<br />

”<br />

<strong>ms</strong> canada Fall/Winter 2012 7

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