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Welcome to Dermatopathology - Dermatology

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<strong>Welcome</strong> <strong>to</strong> Derma<strong>to</strong>pathology!!<br />

DERMATOPATHOLOGY<br />

Updated 6/08<br />

The Derma<strong>to</strong>pathology Section at UCSF is the most active university-based dermpath<br />

service on the West Coast. We aim <strong>to</strong> provide a stimulating and educational experience.<br />

Our service handles wet tissue specimens sent directly <strong>to</strong> us both from the Derma<strong>to</strong>logy<br />

Clinic at UCSF and by outside private practitioners, as well as consultations on previously<br />

prepared glass slides from both clinical derma<strong>to</strong>logists and pathologists. Our <strong>to</strong>tal<br />

accession volume exceeds 85,000 specimens and is growing.<br />

The full-time attending staff consists of Drs. Philip LeBoit, Tim McCalmont, and Beth<br />

Ruben. The derma<strong>to</strong>pathology service is located at 1701 Divisadero St., Third Floor<br />

(corner of Sutter and Divisadero), across from Mt. Zion Hospital. The academic office is in<br />

Room 350, and is administered by Mary Kate Fitzsimon (353-7416). This office handles<br />

academic activities. The staff of the UCSF Derma<strong>to</strong>pathology Service are in Room C101<br />

(first floor of Mt. Zion Hospital), phone 353-7546. Wet tissue specimens and previously<br />

prepared glass slide consultations from derma<strong>to</strong>logists and pathologists outside the<br />

University are handled through this office. The Service office manager is Al Naklowycz, in<br />

Room C101 (phone 353-7535).<br />

Resident Sign-out and Conference Schedule<br />

While on Derma<strong>to</strong>pathology Rotation<br />

7:30 – 8:30 AM<br />

DERMPATH<br />

LECTURE<br />

1701 Divisadero<br />

Room #3100<br />

9:00 AM - 12 PM<br />

SIGNOUT<br />

1701 Divisadero<br />

Room #450<br />

12:45 PM DAILY<br />

CONSENSUS<br />

CONFERENCE<br />

All dermpath faculty<br />

1701 Divisadero<br />

Room #450<br />

M T W TH F<br />

7:30 – 8:10 AM<br />

DERM<br />

RESIDENT<br />

SCOPE<br />

SESSION<br />

1701 Divisadero<br />

Room #450<br />

9:00 AM - 12 PM<br />

SIGNOUT<br />

1701 Divisadero<br />

Room #450<br />

12:45 PM DAILY<br />

CONSENSUS<br />

CONFERENCE<br />

All dermpath<br />

faculty<br />

1701 Divisadero<br />

Room #450<br />

8:00 – 9:00 AM<br />

Derm Grand<br />

Rounds<br />

Herbst Hall, Mt. Zion<br />

9:00 -10:00 AM<br />

Staff Conference<br />

1701 Divisadero<br />

(Pt viewing 3 rd Floor<br />

clinic; discussion 1st<br />

Floor Conference<br />

Room)<br />

10:00 AM - 12 PM<br />

SIGNOUT<br />

1701 Divisadero<br />

Room #450<br />

12:45 PM DAILY<br />

CONSENSUS<br />

CONFERENCE<br />

All dermpath faculty<br />

1701 Divisadero<br />

Room #450<br />

9:00 AM–12:00PM<br />

SIGNOUT<br />

1701 Divisadero<br />

Room #450<br />

12:45 PM DAILY<br />

CONSENSUS<br />

CONFERENCE<br />

All dermpath<br />

faculty<br />

1701 Divisadero<br />

Room #450<br />

9:00 AM –12:00 PM<br />

SIGNOUT<br />

1701 Divisadero<br />

Room #450<br />

12:45 PM DAILY<br />

CONSENSUS<br />

CONFERENCE<br />

All dermpath<br />

faculty<br />

1701 Divisadero<br />

Room #450<br />

REVISED 6-23-2009 1


DERMATOPATHOLOGY<br />

Morning signout will be conducted by the dermpath faculty on consultation material. As<br />

the pace of signout can be rapid, we encourage you <strong>to</strong> ask <strong>to</strong> see a slide we have<br />

reviewed on your own if you need more time <strong>to</strong> study it. We will also tell the UCSF<br />

derma<strong>to</strong>logy resident on the rotation how <strong>to</strong> arrange <strong>to</strong> spend a 1-2 hour session with our<br />

grossing supervisor, David Marrs, <strong>to</strong> gain a better understanding of how tissue is handled<br />

after receipt. The derma<strong>to</strong>logy resident will also spend a session with Dr. Kari Connolly in<br />

the immunofluorescence labora<strong>to</strong>ry. These are required.<br />

The Consensus Conference meets daily promptly at 12:45 PM, during which time the<br />

dermpath faculty bring cases for interest or consultation.<br />

Derma<strong>to</strong>logy Grand Rounds (a 1-hour lecture on an important <strong>to</strong>pic regarding clinical<br />

derma<strong>to</strong>logy or derma<strong>to</strong>pathology) is from 8-9 on most Wednesday mornings. Please<br />

check with the online schedule of the Derma<strong>to</strong>logy Department for the month or months<br />

you are on rotation. Derma<strong>to</strong>logy "Staff Conference" (from 9-10 on Wednesday mornings)<br />

is one of the opportunities <strong>to</strong> see patients during the rotation. The derma<strong>to</strong>pathologic<br />

findings are often presented as well. Attendance is expected. The derma<strong>to</strong>logy and<br />

pathology departments also have other conferences which may be of interest – ask for the<br />

month’s schedule.<br />

The afternoons on the rotation have been reserved for your independent study, while<br />

teaching signout may continue in<strong>to</strong> the afternoon on occasion. Many resources are<br />

available with respect <strong>to</strong> how <strong>to</strong> make the most of this time (see below).<br />

Derma<strong>to</strong>pathology Etiquette<br />

The learning environment around the microscope may be different than you have<br />

encountered previously. So we offer a few words on that account:<br />

1. Please be on time <strong>to</strong> teaching signout (which may vary slightly in its start time,<br />

but will not start before 9 AM), teaching sessions and faculty consensus<br />

conference, <strong>to</strong> avoid disruption.<br />

2. While it is fine <strong>to</strong> bring reading material <strong>to</strong> refer <strong>to</strong> during the session, please<br />

keep conversation <strong>to</strong> a minimum, especially while the faculty is dictating.<br />

Remember, it is a working signout, while also a teaching session. There is also<br />

important learning information being transmitted about the material during<br />

dictation, so listen in.<br />

3. Unless there is an urgent need, please keep your cell phones and pagers in<br />

silent mode.<br />

4. It is alright <strong>to</strong> bring a beverage in<strong>to</strong> the scope room, but no food please.<br />

REVISED 6-23-2009 2


Perspective on the UCSF Derma<strong>to</strong>pathology Service<br />

DERMATOPATHOLOGY<br />

The UCSF Derma<strong>to</strong>pathology Service has evolved in<strong>to</strong> the only vehicle at the University<br />

for the instruction of skin pathology <strong>to</strong> both pathologists and derma<strong>to</strong>logists. Without the<br />

service, much of the breadth and volume of the dermpath experience we provide would be<br />

lost. Residents on the rotation have an active role in the service, and interpretation of<br />

specimens by the attending is done in the presence of the residents and fellows. Keep in<br />

mind that our service attempts <strong>to</strong> meet the financial challenges of managed care, while<br />

simultaneously providing "cutting edge" diagnostic work with maximal information provided<br />

on each specimen.<br />

Case Numbering Systems and Retrieval of Results<br />

Cases prior <strong>to</strong> 1995 were assigned <strong>to</strong> one of multiple numbering systems, depending upon<br />

how the case arrived at the service. All cases after 1995 are assigned a unique accession<br />

number consisting of the year, then a hyphen, then an additional number (for example, the<br />

first case accessioned in 1998 was “98-00001”; the second case was “98-00002.”) Each<br />

case is also assigned <strong>to</strong> a lettering system, depending upon how the case entered the<br />

department and some other fac<strong>to</strong>rs. The lettering system is generally used for billing and<br />

statistical purposes and can be ignored for the most part. Some letters you may see are<br />

DT – wet tissue specimens originating from outside the hospital<br />

DS – slide consultations<br />

DH – all hospital cases, whether inpatient or outpatient<br />

DI -- immunofluorescence cases<br />

DR – research cases<br />

DN – no charge cases<br />

Different departments of the hospital use different report retrieval systems which are not<br />

completely linked. Almost all reports after 1990 can be retrieved through the Intellipath<br />

system, which is found only on terminals within the derma<strong>to</strong>pathology offices. The<br />

personnel in the Service office at 353-7546 will be happy <strong>to</strong> retrieve these reports for you.<br />

Reports prior <strong>to</strong> 1990 can be obtained through Mary Kate Fitzsimon in the Academic office.<br />

Some cases are logged in<strong>to</strong> the Co-path system found in the pathology department, but<br />

the diagnoses and reports for those cases are usually NOT entered in<strong>to</strong> this system and<br />

the cases usually appear as “incomplete” even after they are signed out. A patient who<br />

has a UC identification number which is known <strong>to</strong> the derma<strong>to</strong>pathology service (in other<br />

words, the patient was seen within the medical center) should have a complete report<br />

available within the STOR system.<br />

REVISED 6-23-2009 3


Available Educational Materials in Derma<strong>to</strong>pathology<br />

DERMATOPATHOLOGY<br />

The standard texts are Weedon’s Skin Pathology*, Lever's His<strong>to</strong>pathology of the Skin, and<br />

McKee’s Pathology of the Skin. Chapters from Maize’s Cutaneous Pathology are<br />

generally the basis for the Derma<strong>to</strong>pathology lectures on Monday mornings. These are all<br />

available in our office, as is the most comprehensive text on inflamma<strong>to</strong>ry skin disease,<br />

Ackerman's His<strong>to</strong>pathology of Inflamma<strong>to</strong>ry Skin Disease: A Method by Pattern Analysis.<br />

There are also a number of monographs available on specific <strong>to</strong>pics in Derma<strong>to</strong>pathology,<br />

such as adnexal neoplasms, melanoma, and lymphomas. The best way <strong>to</strong> develop skill in<br />

the field is <strong>to</strong> read about cases you encounter and <strong>to</strong> master basic derma<strong>to</strong>pathologic<br />

concepts. Please do not remove these resources from the Department. Depending of<br />

course on your background, during the rotation, you should work <strong>to</strong>ward mastery of the<br />

following introduc<strong>to</strong>ry <strong>to</strong>pics:<br />

1. pattern analysis of basal cell carcinoma<br />

2. types of melanocytic nevi and eponymic naming of nevi<br />

3. architectural criteria for recognition of melanoma and distinction of melanoma from<br />

melanocytic nevi<br />

4. architectural criteria for mycosis fungoides<br />

5. recognition of the basic patterns of inflamma<strong>to</strong>ry skin disease, with a brief<br />

differential diagnosis for each pattern.<br />

*UCSF residents may check out a copy of Weedon’s during their rotation, from our<br />

academic office. All first year UCSF derma<strong>to</strong>logy residents will be provided with their own<br />

copy compliments of the Derma<strong>to</strong>pathology faculty.<br />

In addition, there is a list of dermpath diagnoses that each UCSF derma<strong>to</strong>logy resident<br />

should master according <strong>to</strong> their year of training, which can be found in the derma<strong>to</strong>logy<br />

resident glass slide collection. Please make sure that those have been studied during your<br />

time on the rotation.<br />

An invaluable correlate for pathology residents rotating through derma<strong>to</strong>pathology is a<br />

basic knowledge of clinical derma<strong>to</strong>logy. The paperback by Lookingbill and Marks, Clinical<br />

Derma<strong>to</strong>logy, is the one used as an introduction for residents and medical students<br />

rotating through derma<strong>to</strong>logy. We highly recommend that you read the book in its entirety<br />

at the start of your rotation. The brief paperback, Derma<strong>to</strong>pathology by Burgdorf<br />

(Springer-Verlag, 1984) can also be read in its entirety and provides a valuable overview.<br />

We have lost our copy of this book, but you may be able <strong>to</strong> find one elsewhere.<br />

There are glass slide collections available in the scope room – we would encourage you <strong>to</strong><br />

use them. Looking at unknown cases and then reading about the entities you encounter is<br />

one of the best ways <strong>to</strong> gain skill in any pathology discipline, including derma<strong>to</strong>pathology.<br />

The importance of reading during the rotation cannot be overstated.<br />

Another informative study <strong>to</strong>ol is the website http://www.mdlive.net/ Under Program<br />

Series Available, there is the Derma<strong>to</strong>pathology Master Series covering many <strong>to</strong>pics on<br />

derma<strong>to</strong>pathology. Under “Archived Lectures”, find Derma<strong>to</strong>pathology Master Classes for<br />

the available programs. Sign the Guest Book (no password required) <strong>to</strong> access the<br />

lectures.<br />

REVISED 6-23-2009 4


Rules regarding study set slides<br />

DERMATOPATHOLOGY<br />

1. All boxes should be maintained in consecutive order within their present<br />

location.<br />

2. Only one box will be removed for study at a time.<br />

3. Slides should be replaced in<strong>to</strong> the proper slot in the box. Please do not leave<br />

slides out on surfaces.<br />

4. When study of the cases from one box has been completed, this box should be<br />

replaced and then the new box can be removed for study.<br />

5. The slide boxes should never be left at your microscope but should be replaced<br />

in the filing location as soon as you have finished your study. This means that<br />

all boxes should be replaced over lunch and overnight.<br />

6. Please notify Mary Kate regarding any missing slides (include the box number<br />

and the case number). They will consult with us <strong>to</strong> determine if replacement is in<br />

order.<br />

7. Please notify Mary Kate if you believe there is a case with an incorrect diagnosis.<br />

They will consult with us <strong>to</strong> see if a correction is necessary.<br />

8. Slide boxes may not be removed from the Department for any reason.<br />

Clinicopathologic correlation<br />

We are occasionally asked as a group <strong>to</strong> see patients in the derma<strong>to</strong>logy clinic for<br />

clinicopathologic correlation. As such, please dress professionally (no sweats, scrubs,<br />

jeans or tennis shoes). Be considerate of the patient’s privacy and reserve any<br />

commentary <strong>to</strong> a time when outside the examination room.<br />

Immunofluorescence and Specialty Clinics in the UCSF Derma<strong>to</strong>logy Department<br />

Since 1995, immunofluorescence diagnostic testing has been available through our<br />

service by Dr. M. Kari Connolly. Talk <strong>to</strong> us for additional information regarding Dr.<br />

Connolly’s signout schedule. Signout sessions will be arranged for the derma<strong>to</strong>logy<br />

resident on the rotation. There are two specialty clinics that may be of interest. The<br />

Melanoma Clinic and Cutaneous Lymphoma Clinic, headed by Dr. Mohammed Kashani-<br />

Sabet, provide an opportunity <strong>to</strong> see patients with disorders in which clinicopathologic<br />

correlation is extremely important. Please ask us <strong>to</strong> make arrangements should you wish<br />

<strong>to</strong> observe either clinic.<br />

Research Opportunities<br />

For interested residents and students, a variety of writing and investigative opportunities<br />

are available. Both case reports and projects can be pursued that may culminate in<br />

publication. If you wish <strong>to</strong> consider a research project, see us for ideas and details.<br />

REVISED 6-23-2009 5


Goals and Objectives of Derma<strong>to</strong>pathology<br />

First-Year Residents<br />

1. Learn a general approach <strong>to</strong> his<strong>to</strong>pathologic diagnosis.<br />

DERMATOPATHOLOGY<br />

2. Be able <strong>to</strong> identify common cutaneous neoplasms (i.e. seborrheic kera<strong>to</strong>sis,<br />

malanocytic nevus, etc.) and common inflamma<strong>to</strong>ry patterns (i.e. spongiotic dermatitis,<br />

interface dermatitis, etc.) with reasonable reliability.<br />

3. Understand basic principles of gross pathology: how specimens are “cut in” and how<br />

that affects the practice of pathology.<br />

4. Understand fundamentals of clinicopathologic correlation.<br />

5. Be able <strong>to</strong> rationally explain the fundamental nature of disease processes (i.e. cysts,<br />

malformations, hamar<strong>to</strong>mas, hyperplasias, benign and malignant neoplasms, etc).<br />

6. For UC trainees, review the UCSF derma<strong>to</strong>logy resident slide set of diagnoses based<br />

on your year of training, and read on those as well.<br />

Readings<br />

Skin Pathology, David Weedon; contribu<strong>to</strong>r, Geoffrey Strut<strong>to</strong>n. 2nd ed. London; New York:<br />

Churchill Livings<strong>to</strong>ne, 2002<br />

Also see the Differential Diagnosis I through IV by A. Bernard Ackerman, available in our<br />

library.<br />

REVISED 6-23-2009 6


Goals and Objectives of Derma<strong>to</strong>pathology<br />

Second-Year Residents<br />

1. Learn criteria for specific diseases and be able <strong>to</strong> express them lucidly.<br />

DERMATOPATHOLOGY<br />

2. Develop differential diagnoses for commonly encountered his<strong>to</strong>pathologic patterns.<br />

3. Be able <strong>to</strong> identify and subcategorize, with reasonable reliability for level of training,<br />

variants of common cutaneous neoplasms (i.e. types of basal cell carcinoma, other<br />

carcinomas, melanocytic nevi, etc.).<br />

4. For UC trainees, review the UCSF derma<strong>to</strong>logy resident slide set of diagnoses based<br />

on your year of training, and read on those as well.<br />

Readings<br />

Skin Pathology, David Weedon ; contribu<strong>to</strong>r, Geoffrey Strut<strong>to</strong>n. 2nd ed. London ; New York<br />

: Churchill Livings<strong>to</strong>ne, 2002<br />

REVISED 6-23-2009 7


Goals and Objectives of Derma<strong>to</strong>pathology<br />

Third-Year Residents<br />

1. Learn features of less common diseases, both inflamma<strong>to</strong>ry and neoplastic.<br />

DERMATOPATHOLOGY<br />

2. Learn limitations of microscopic diagnosis (i.e. which diseases cannot be distinguished<br />

microscopically).<br />

3. Be able <strong>to</strong> state some of the arguments on both sides of current debates on major<br />

issues in derma<strong>to</strong>pathology.<br />

4. For UC trainees, review the UCSF derma<strong>to</strong>logy resident slide set of diagnoses based<br />

on your year of training, and read on those as well.<br />

Readings<br />

Skin Pathology, David Weedon ; contribu<strong>to</strong>r, Geoffrey Strut<strong>to</strong>n. 2nd ed. London ; New York<br />

: Churchill Livings<strong>to</strong>ne, 2002<br />

REVISED 6-23-2009 8

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