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Monitoring of Polycyclic Aromatic Hydrocarbons (PAH) in food ...

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peer-00704676, version 1 - 6 Jun 2012<br />

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Table 10. Lower bound mean levels <strong>of</strong> 13 <strong>PAH</strong> <strong>in</strong> 333 supplements sampled <strong>in</strong> 2008 and 2009.<br />

Food Additives and Contam<strong>in</strong>ants<br />

Supplement characteristics N Mean <strong>PAH</strong> concentration (µ g kg-1 ) b<br />

Category Type/ <strong>in</strong>gredient a<br />

BaP BgP BaA BbF BkF CHR DhA DeP DhP DiP DlP 5MC BcL<br />

Fatty acids Miscellaneous<br />

Oenothera biennis (even<strong>in</strong>g primrose)<br />

5 1.94 1.40 0.92 3.80 1.44 0.84 0.14 0 0 0 0.62 0.98 0<br />

seed oil 7 0.87 0 1.20 0.91 0.44 6.37 0 0 0 0.36 0.14 0.24 0<br />

Fish liver oil 4 0.30 0 0 0.40 0.15 1.88 0 0 0 0 0 0.68 0<br />

Botanical Mono-<strong>in</strong>gredient 30 1.06 0.84 0.94 1.67 0.59 3.56 0.12 0 0 0.05 0.45 0.57 0.34<br />

Multi-<strong>in</strong>gredient 111 3.69 2.57 4.33 8.16 2.54 13.8 0.54 0.40 0.05 0.10 1.08 2.20 2.04<br />

Multivitam<strong>in</strong>, with botanicals 12 2.93 2.86 3.14 3.53 1.74 10.7 0.36 0 0 0.07 0.34 0.20 1.41<br />

Ayurvedic, multi-<strong>in</strong>gredient 12 2.03 1.44 0.63 1.98 1.02 7.28 0.21 0.30 0 0.12 0.37 10.2 2.42<br />

Ch<strong>in</strong>ese, multi-<strong>in</strong>gredient 11 4.41 2.20 9.04 12.0 1.04 12.6 1.53 18.1 3.31 1.23 6.88 7.33 1.52<br />

Actaea racemosa c (black cohosh) 7 1.51 1.61 0.81 3.30 1.04 1.39 0 0 0 0 0.46 0 0.41<br />

Angelica s<strong>in</strong>ensis (dong quai) 4 3.00 2.43 1.03 5.03 1.95 6.78 0 0 0.23 0 1.25 0.48 9.63<br />

Camellia s<strong>in</strong>ensis (green tea) 18 3.59 3.61 1.62 3.47 1.60 4.86 0.39 0.07 0.12 0.08 1.55 1.23 0.73<br />

G<strong>in</strong>kgo biloba 22 4.32 2.40 7.18 8.5 3.82 26.7 0.53 0.35 0.13 0.37 0.20 1.65 1.23<br />

Glyc<strong>in</strong>e max (soy) prote<strong>in</strong>, is<strong>of</strong>lavones<br />

Hypericum perforatum (St. John's<br />

9 0.27 0 0 0.54 0.28 1.21 0.34 0 0 0 0 0 0<br />

wort) 14 6.89 6.78 7.8 9.9 5.78 15.7 2.91 0.41 0.13 0.14 2.19 2.46 3.66<br />

Panax g<strong>in</strong>seng (g<strong>in</strong>seng) 8 0.71 0.34 0.53 0.61 0.49 0 0.10 0 0 0 0 2.88 0.20<br />

Resveratrol d 7 36.8 21.8 28.4 43.0 16.9 74.4 5.34 3.73 1.06 0.77 11.1 26.8 17.9<br />

Resveratrol, multi-<strong>in</strong>gredient 14 36.1 19.3 15.2 35.5 14.7 65.4 3.66 1.74 0.94 3.41 11.5 6.99 76.2<br />

Rhodiola rosea (golden root) 5 2.74 1.90 2.94 2.80 1.38 3.90 0.44 0 0.36 0 0.26 0 0.54<br />

Vacc<strong>in</strong>um spp. (cranberry) 5 0.60 0 0 0.56 0.26 0 0 0 0 0 0 0 0<br />

Valeriana <strong>of</strong>fic<strong>in</strong>alis (valerian) 8 4.64 1.44 6.90 4.45 2.46 4.18 0 0 0 0 1.29 0.49 0.36<br />

Other Miscellaneous, without botanicals 9 2.14 3.12 0 2.50 0.83 3.22 0 1.41 0 0.30 1.14 2.18 0<br />

Notes:<br />

Propolis, pollen, royal jelly 11 7.63 1.96 24.2 9.47 4.08 58.4 1.18 0.84 0 0 1.16 15.4 5.37<br />

a When one <strong>in</strong>gredient is listed, this substance generally represents the only ‘active’ <strong>in</strong>gredient <strong>in</strong> this group.<br />

b See table 1 for the abbreviations used for the 13 EFSA priority <strong>PAH</strong> determ<strong>in</strong>ed <strong>in</strong> this survey.<br />

c Syn. Cimicifuga racemosa.<br />

d 6 out <strong>of</strong> 8 supplements labeled a Polygonum cuspidatum-extract as the source <strong>of</strong> resveratrol.<br />

For Peer Review Only<br />

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