jennifer macalindong de guzman - LSU Department of Chemistry ...
jennifer macalindong de guzman - LSU Department of Chemistry ...
jennifer macalindong de guzman - LSU Department of Chemistry ...
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EDUCATION<br />
JENNIFER MACALINDONG DE GUZMAN<br />
3650 Nicholson Dr., Apt. 1157<br />
Baton Rouge LA 70802<br />
225‐276‐4127 (mobile)<br />
jmacal4@tigers.lsu.edu<br />
• PhD, <strong>Chemistry</strong>, 2009 (expected), Louisiana State University, Baton Rouge LA<br />
Thesis title: “Development <strong>of</strong> Serial Micr<strong>of</strong>luidic Platform for Glycoprotein Screening”<br />
Adviser: Pr<strong>of</strong>. Robin L. McCarley<br />
• BS, <strong>Chemistry</strong>, April 2000, University <strong>of</strong> the Philippines (cum lau<strong>de</strong>)<br />
Thesis title: Development <strong>of</strong> Papain‐modified Carbon Paste Electro<strong>de</strong> for Hg(II) <strong>de</strong>termination<br />
Adviser: Dr. Jose H. Santos<br />
HIGHLIGHTS<br />
• Specialization in capture/enrichment <strong>of</strong> glycosylated proteins using boronic acid‐chemically<br />
modified polymer micr<strong>of</strong>luidic surfaces and lectin‐modified gold surfaces and their<br />
characterization with surface analytical methods<br />
• Experienced in polymer chemistry such as conventional free radical polymerization (FRP) and<br />
atom transfer radical polymerization (ATRP) both in solution and on surfaces<br />
• Expert in a variety <strong>of</strong> surface analytical methodologies and techniques<br />
• Extensive teaching experience<br />
RESEARCH SKILLS AND EXPERTISE<br />
• X‐ray photoelectron spectroscopy<br />
• Surface Plasmon Resonance<br />
spectroscopy<br />
• Contact Angle Goniometry<br />
• Ellipsometry<br />
• FT‐IR spectroscopy (transmission and<br />
reflection‐absorption)<br />
1<br />
• H‐NMR spectroscopy<br />
• Atomic absorption spectroscopy<br />
• Atomic force microscopy<br />
• SDS‐PAGE<br />
• Fluorescence spectroscopy and<br />
microscopy<br />
• UV‐visible absorption spectroscopy<br />
• Voltammetry
RESEARCH EXPERIENCE<br />
JENNIFER MACALINDONG DE GUZMAN<br />
Graduate Research Louisiana State University, Baton Rouge LA June 2005‐present<br />
• Tailor‐ma<strong>de</strong>, receptor‐modified micr<strong>of</strong>luidic surfaces, i.e. boronic acid<br />
<strong>de</strong>rivatives and protein‐sugar‐polymer conjugates, for glycoprotein analysis<br />
• Critical evaluation <strong>of</strong> surface properties using a variety <strong>of</strong> analytical tools<br />
• Assessment <strong>of</strong> a boronic acid capture agent that operates at physiological pH<br />
using surface plasmon resonance spectroscopy<br />
• Grafting from gold surfaces by atom transfer radical polymerization (ATRP)<br />
Un<strong>de</strong>rgraduate Research University <strong>of</strong> the Philippines June 1999‐April 2000<br />
TEACHING EXPERIENCE<br />
• Designed electro<strong>de</strong> surfaces modified with the cysteine protease<br />
enzyme papain and evaluated its performance using electrochemical<br />
measurements (i.e. Voltammetry) for <strong>de</strong>tection <strong>of</strong> Hg(II)<br />
Teaching Assistant <strong>Department</strong> <strong>of</strong> <strong>Chemistry</strong>, Louisiana State University<br />
August 2004‐December 2006<br />
• 7 terms including Summer<br />
• Analytical <strong>Chemistry</strong> Laboratory, Year Level 2 (sophomore)<br />
• Instrumental Analysis Laboratory, Year Level 4+ (senior and graduate)<br />
Supervised laboratories and gra<strong>de</strong>d evaluation materials<br />
<strong>Chemistry</strong> Instructor Institute <strong>of</strong> <strong>Chemistry</strong>, University <strong>of</strong> the Philippines June 2001‐May 2004<br />
• 8 terms including Summer<br />
• General <strong>Chemistry</strong> Laboratories<br />
• Organic <strong>Chemistry</strong> Laboratories<br />
• Analytical <strong>Chemistry</strong> Laboratory<br />
Supervised laboratories, conducted lectures, and prepared and gra<strong>de</strong>d<br />
evaluation materials<br />
Lecturer May 2003‐June 2004<br />
Scilinks Incorporated (A Review Organization for Pr<strong>of</strong>essional <strong>Chemistry</strong><br />
Licensure Examinees), Laguna, Philippines<br />
Analytical <strong>Chemistry</strong><br />
Conducted lecture presentations and prepared evaluation materials
PUBLICATIONS AND PRESENTATIONS<br />
JENNIFER MACALINDONG DE GUZMAN<br />
De Guzman, J. M.; McCarley, R. L. Reversible glycoprotein capture by surface‐immobilized boronic acids<br />
possessing a low pKa. An oral presentation at the 237 th National Meeting <strong>of</strong> the A merican<br />
Chemical Society, Salt Lake City, UT, March 2009.<br />
De Guzman, J. M.; McCarley, R. L. Development <strong>of</strong> Affinity Matrices on Micr<strong>of</strong>luidic Surfaces to Capture<br />
Glycoproteins. An oral presentation at the Pittsburgh Conference, New Orleans, LA, March 2008.<br />
De Guzman, J. M.; McCarley, R. L. Modification <strong>of</strong> Micr<strong>of</strong>luidic Surface with Protein‐Polymer Conjugates<br />
for the Capture <strong>of</strong> Glycoproteins. A poster communication presented at the 234 th National<br />
Meeting <strong>of</strong> the American Chemical Society, Boston, MA, August 2007.<br />
Macalindong, J. S.; Fronczek, F. R.; Schuerman, J. A.; Selbin, J.; Watkins, S. F. (2‐methyldithiobenzoato‐<br />
κS)(triphenylphosphine‐κO)gold(I). Acta Cryst. 2006, E62, m889‐m890.<br />
AWARDS AND AFFILIATIONS<br />
• Coates Graduate Travel Award, Louisiana State University, 2007 & 2009<br />
• Excellence in Analytical <strong>Chemistry</strong> Teaching Award, Louisiana State University, 2006<br />
• Merck Graduate Analytical/Physical Travel Award, 2005‐2006<br />
• <strong>Chemistry</strong> Licensure Examination, 6 th place, Philippines, 2000<br />
• American Chemical Society<br />
REFERENCE<br />
Pr<strong>of</strong>. Robin L. McCarley<br />
Analytical and Materials <strong>Chemistry</strong><br />
232 Choppin Hall, Louisiana State University, Baton Rouge LA 70803<br />
225‐578‐3239 (<strong>of</strong>fice)<br />
tunnel@lsu.edu