Klatskin tumors and other cholangiocarcinoma - Lieberman's ...

More documents

Recommendations

Info

Risk Factors Primary sclerosing cholangitis Lifetime risk: 10-15% Average age at time of diagnosis: 30s-50s Fibropolycystic liver disease i.e. Caroli’s syndrome, congenital hepatic fibrosis, choledochal cysts Lifetime risk: 15% Average age at time of diagnosis: 30s-50s Parasitic Infection Liver flukes of Clonorchis and Opisthorchis genera (from undercooked fish) Cholelithiasis and haptolithiasis Toxic exposure Thorotrast Lynch syndrome and biliary papillomatosis Chronic liver disease Viral hepatitis 16
Common Clinical Manifestations Symptoms: Pruritus (66%) RUQ pain (30-50%) Weight loss (30-50%) Fever (20%) Acholic stools; dark urine Cholangitis (rare) Physical Signs: Jaundice (90%) Hepatomegaly (25-40%) RUQ mass (10%) Courvoisier’s sign (rare) 17
Page 1 and 2: Klatskin tumors and other cholangio
Page 3 and 4: Index Patient: KR 53M presented to
Page 5 and 6: Patient KR: Conjugated Hyperbilirub
Page 7 and 8: Review of Biliary Anatomy Plate 260
Page 9 and 10: Patient KR: Biliary Dilatation on R
Page 11 and 12: Patient KR: Hilar Stricture on ERCP
Page 13 and 14: Patient KR: Bile Duct Dilatation an
Page 15: Cholangiocarcinoma: Pathogenesis an
Page 19 and 20: Bismuth-Corlette Classification Hi
Page 21 and 22: Surgical resection is the only cura
Page 23 and 24: Criteria for Resectability of Hilar
Page 25 and 26: Example of Unresectable Tumor: Celi
Page 27 and 28: Discussion of Companion Patients 27
Page 29 and 30: Patient 2: Hyper-enhancement on Del
Page 31 and 32: Patient 2: Gallbladder Wall Invasio
Page 33 and 34: Patient 3: Liver Metastasis on HAST
Page 35 and 36: Summary (1) Cholangiocarcinoma can
Page 37 and 38: References Anderson C and stuart K

Klatskin tumors and other cholangiocarcinoma - Lieberman's ...

Create successful ePaper yourself

Delete template?

Save as template?