Klatskin tumors and other cholangiocarcinoma - Lieberman's ...

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Patient KR: Likely Biliary Obstruction Our patient also had a markedly elevated alkaline phosphatase (AP), but only a mildly elevated AST and ALT AP is made by the canilicular cells lining the biliary ducts AST and ALT are made by hepatocytes A markedly elevated AP, relative to AST and ALT, implies that the site of injury is in the biliary ducts Thus, we can infer that our patient likely has a biliary obstruction leading to jaundice 6
Review of Biliary Anatomy Plate 260, Netter’s Atlas of Human Anatomy 4 th Ed. Beaumont Hospitals. https://www.beaumonthospitals.com/health-library/P07694 7
Page 1 and 2: Klatskin tumors and other cholangio
Page 3 and 4: Index Patient: KR 53M presented to
Page 5: Patient KR: Conjugated Hyperbilirub
Page 9 and 10: Patient KR: Biliary Dilatation on R
Page 11 and 12: Patient KR: Hilar Stricture on ERCP
Page 13 and 14: Patient KR: Bile Duct Dilatation an
Page 15 and 16: Cholangiocarcinoma: Pathogenesis an
Page 17 and 18: Common Clinical Manifestations Sym
Page 19 and 20: Bismuth-Corlette Classification Hi
Page 21 and 22: Surgical resection is the only cura
Page 23 and 24: Criteria for Resectability of Hilar
Page 25 and 26: Example of Unresectable Tumor: Celi
Page 27 and 28: Discussion of Companion Patients 27
Page 29 and 30: Patient 2: Hyper-enhancement on Del
Page 31 and 32: Patient 2: Gallbladder Wall Invasio
Page 33 and 34: Patient 3: Liver Metastasis on HAST
Page 35 and 36: Summary (1) Cholangiocarcinoma can
Page 37 and 38: References Anderson C and stuart K

Klatskin tumors and other cholangiocarcinoma - Lieberman's ...

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