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Science & Technology News from Japan - International Relations

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Schweizerische Eidgenossenschaft<br />

Confédération suisse<br />

Confederazione Svizzera<br />

Confederaziun svizra<br />

First CT Scan Of Coelacanth-Fish Eggs<br />

Embassy of Switzerland in <strong>Japan</strong><br />

State Secretariat for Education and Research SER<br />

(March 20, 2009)<br />

Researchers at Tokyo Institute of <strong>Technology</strong> carried out what is believed to be the first CT<br />

scan of eggs inside a coelacanth. About 40 eggs were photographed inside each of the two<br />

coelacanths, which were captured off the coast of Tanzania, frozen and transported to Tokyo.<br />

The fishes are 170 cm long and weigh 70 kg each, while their eggs are about 7 cm in<br />

diameter. Coelacanths are thought to represent an early step in the evolution of fish to amphibians.<br />

The eggs hatch while still inside the female and the young grow to 30 cm in length before they emerge.<br />

Antibody Drug For Colorectal Cancer<br />

(March 27, 2009)<br />

Takeda Pharmaceutical Co. will market an antibody drug for colorectal cancer. Takeda currently sells only one<br />

such drug for treating prostate cancer and revenue <strong>from</strong> the cancer field accounts for only around 15% of its total<br />

sales. The company aims to broaden its lineup of cancer drugs because the market for its mainline drugs for blood<br />

pressure and other lifestyle diseases has flattened in <strong>Japan</strong>. Its patents on drugs for ulcers, blood pressure and<br />

diabetes will be expiring in the U.S. over the next few years. <strong>Japan</strong>'s Health Ministry has approved the monoclonal<br />

antibody drug, for cancers of the colon and rectum.<br />

New Antibody Drug For Ovarian Cancer In Clinical Testing<br />

(March 27, 2009)<br />

Eisai Co. will begin phase III trials in the U.S. on an antibody drug for treating ovarian cancer. The drug was developed<br />

by U.S. biopharmaceutical firm Morphotek Inc., which Eisai acquired in 2007. It is the first of the company's<br />

antibody drug candidates to make it to the third and final phase of clinical testing. The U.S. Food & Drug Administration<br />

recently approved a phase III trial in combination with standard chemotherapy drugs carboplatin and taxane<br />

to treat ovarian cancer. The antibody drug fights cancer in two ways: stimulating the immune system to attack<br />

the cancer cells and blocking a signaling pathway that promotes cell proliferation.<br />

More Efficent Cervical Cancer Vaccine<br />

(March 30, 2009)<br />

The National Institute of Infectious Diseases and other institutions have developed a next-generation vaccine<br />

against human papillomavirus (HPV). While anti-cervical cancer vaccine prevents 60% to 70% of uterine cervical<br />

cancer, the new vaccine is expected to be more effective. Of the 100 different types of HPV, 15 can cause cervical<br />

cancer. Researchers at the institute found in experiments conducted on animals that an antibody made by using a<br />

surface protein commonly found in 15 types of HPV was effective in protecting against at least eight types of HPV.<br />

Vaccines used overseas are effective against only two to four HPV types, as the vaccines are manufactured using<br />

proteins found in specific HPVs.<br />

4. Nano / Micro <strong>Technology</strong> / Material <strong>Science</strong><br />

Various Nanofiber Developments<br />

Tokyo Institute of <strong>Technology</strong> makes sheets by electro-spinning nanofibers and letting them<br />

pile up at the bottom of a container. It has also managed to grow nanofibers of zinc oxide on<br />

the surface of a sheet of carbon nanofibers. The carbon nanofibers are 100nm in diameter<br />

and the zinc oxide nanofibers are 50nm in diameter. When the surface of these zinc oxide<br />

nanofibers are coated with a photosensitive dye, the construction operates as a type of dyesensitized<br />

solar cell, generating electricity in the presence of sunlight. Kyoto University uses<br />

laser light to fabricate nanofiber structures with diameters of just tens of nanometers inside clear glass.<br />

(March 01, 2009)<br />

Nanofiber Experimental Research For New Technologies<br />

(March 08, 2009)<br />

The Nanofiber Society wants to help make sure <strong>Japan</strong> stands there at the cutting edge when the fruits of experimental<br />

research seed new nanofiber-related industries. Set up in December of last year, the society is chaired by<br />

Tokyo Institute of <strong>Technology</strong> Professor Akihiko Tanioka, whose work with organic nanofibers has taken that field<br />

to new heights. But the society is not focused entirely on organic materials and makes a point of soliciting the participation<br />

of specialists <strong>from</strong> the various branches of materials science, including inorganic materials and metals.<br />

<strong>Japan</strong> has already made a contribution to global research in this field.<br />

<strong>Science</strong> & <strong>Technology</strong> <strong>News</strong> <strong>from</strong> <strong>Japan</strong>, Template 2009 • Felix Moesner, <strong>Science</strong> & <strong>Technology</strong> Attaché Page 6 of 28

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