APV FOCUS GROUP DRUG DELIVERY

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DRUG DELIVERY ACADEMIC RESEARCH GROUPS BACK TO TABLE OF CONTENTS Provided by Dr. Michael Horstmann This new newsletter section is intended to give a brief overview of academic groups based at European Universities. In this issue the focus is on groups working on transdermal technology research. It is the first of an occasional series reviewing the work of research groups exploring different aspects of drug delivery research. It is not intended to be a comprehensive list of those involved in the area but give our readers a flavour of the groups involved. As it is a living document, our readers are most welcome to suggest other transdermal research teams they are aware of for inclusion in our next edition. Contact Bath Institution United Kingdom, Bath: University of Bath Group The Department of Pharmacy and Pharmacology Key contact Prof. Richard H. Guy Website http://www.bath.ac.uk/pharmacy/staff/rhg2.html E-Mail r.h.guy@bath.ac.uk Research areas Braunschweig • Topical bioavailability of drugs and other skin-active species • Mechanisms of iontophoretic drug delivery across skin • Prediction and assessment of dermal exposure Institution Germany, Braunschweig: Technische Universität Carolo-Wilhelmina Group Institut für Pharmazeutische Technologie Key contact Prof. Dr Christel Müller-Goymann Website http://www.pharmtech.tu-bs.de/ E-Mail c.mueller-goymann@tu-bs.de Research areas Erlangen • Colloidal drug delivery systems – Development and characterization • Penetration / Permeation into human skin • Cell cultivation methods for permeation studies Institution Germany, Erlangen: Friedrich-Alexander-Universität Group Division of Pharmaceutics Key contact Prof Geoffrey Lee, Chair of Pharmaceutics Website http://www.pharmtech.uni-erlangen.de/ E-Mail lee@pharmtech.uni-erlangen.de Research areas Geneva • Solubility and release • Thermodynamic activity concepts in polymeric matrices • Needle free injection Institution Switzerland, Geneva: University of Geneva School of Pharmaceutical Sciences Group Skin Bioengineering Group Key contact Dr. Yogeshvar N. Kalia Website http://www.unige.ch/sciences/pharm/sbg/kalia-STG.html e-Mail yogi.kalia@unige.ch Research areas • Development of new formulations for topical delivery • Investigating the iontophoretic transport of peptides and proteins across the skin –non-invasive delivery of therapeutic molecules and the elucidation of structuretransport relationships • Development of minimally-invasive technologies for transdermal delivery of macromolecules – proteins and antibodies. • Modification of drug structure and molecular properties to design therapeutics better suited to transdermal administration. APV Drug Delivery Focus Group Newsletter – 2/2011 Page 6 of 15
Halle Institution Germany, Halle-Wittenberg: Martin-Luther-Universität Group Pharmazeutische Technologie und Biopharmazie/ AG Biopharmazie Key contact Prof. Dr. Reinhard Neubert Website http://pharmtech.pharmazie.uni-halle.de/deutsch/ag-biopharm/ E-Mail neubert@pharmazie.uni-halle.de Research areas Hamburg • Barrier function of stratum corneum • Stratum corneum lipids and their interference (e.g. ion-pairs) • Institut für Angewandte Dermatopharmazie (w. Prof. W. Wohlrab) Institution Germany, Hamburg: Universität Hamburg Group Lehrstuhl für Pharmazeutische Technologie Key contact Prof. Dr. Claudia S. Leopold Website http://www.chemie.uni-hamburg.de/pha/phatech/mitarbeiter/leopold.html E-Mail Claudia.Leopold@uni-hamburg.de Research areas Leiden • Quantification and optimisation of the penetration of actives through the skin Institution The Netherlands, Leiden: Leiden/Amsterdam Center for Drug Research Group Drug Delivery Technology – Skin Research Group Key contact Prof. Dr. Joke Bouwstra Website http://ddt.lacdr.gorlaeus.net/people/bouwstra E-Mail bouwstra@lacdr.leidenuniv.nl bouwstra@chem.leidenuniv.nl Research areas London • Stratum corneum substitute research • Dermal vaccine delivery with elastic vesicles • Lipid organization in healthy and diseased skin • Optimisation and application of human skin equivalents • (Pro)drugs for iontophoretic delivery Institution United Kingdom, London: University of London Group The School of Pharmacy Key contact Dr. Majella Lane / Prof. em. Dr. Jon. Hadgraft Website http://www.pharmacy.ac.uk/majella_lane.html E-Mail majella.lane@btinternet.com Research areas • Transdermal and topical drug delivery • Mechanisms of penetration enhancement • Percutaneous absorption APV Drug Delivery Focus Group Newsletter – 2/2011 Page 7 of 15
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