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The Brain: Structure and Function

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<strong>The</strong> <strong>Brain</strong>: <strong>Structure</strong> <strong>and</strong> <strong>Function</strong><br />

• <strong>The</strong> brain grows to 3 pounds across 20 years<br />

• “Ontology recapitulates phylogeny”<br />

– structures arise in the course of development <strong>and</strong> mirror evolution<br />

• hindbrain: Medulla, pons, cerebellum<br />

• midbrain: superior colliculi, reticular, etc.<br />

• forebrain: higher cognitive functions


Cortical Orientation<br />

• Directions: Lateral/medial, dorsal/ventral, anterior/posterior<br />

• Lobes: Frontal, Occipital, Parietal, Temporal


Localization of <strong>Function</strong><br />

• Franz Gall <strong>and</strong><br />

phrenology<br />

– “faculty psychology”<br />

– assumed<br />

• different parts do<br />

different things (yes!)<br />

• size matters (no!)<br />

• different faculties are<br />

independent (no!)


Neuropsychology<br />

• Broca’s aphasia: Failure to produce speech<br />

• Wernicke’s aphasia: Fluent, nonsensical speech


Motor <strong>and</strong> Somatosensory Cortex


Lateralization<br />

• Left goes to right <strong>and</strong> vice versa<br />

• Language on the left (usually)<br />

– larger left hemisphere <strong>and</strong> h<strong>and</strong>edness<br />

– lateralized <strong>and</strong> bilateralized<br />

• Integration of visual <strong>and</strong> auditory on right<br />

– larger right temporal areas<br />

– geometric puzzles, navigation, faces, sports<br />

• Analytic/Synthetic, Left/Right brained<br />

– but these are simplifications<br />

– each hemisphere can do most things<br />

• split brain patients <strong>and</strong> the corpus callosum


Static Imaging Techniques<br />

(CAT, MRI, <strong>and</strong> PET)


<strong>Function</strong>al Imaging Techniques<br />

• Hemodynamic:<br />

– Positron Emission<br />

Topography (PET)<br />

– functional Magnetic<br />

Resonance Imaging<br />

(fMRI)<br />

• Electrophysiology:<br />

– EEG/ERP<br />

– MEG


Subtraction Technique


Electroencephalography (EEG) <strong>and</strong> Event-<br />

Related Potential (ERP)


Presentation<br />

Sequence<br />

Word Priming<br />

doctor<br />

NURSE<br />

Prime: 10 - 2000 ms<br />

Target: ~ 50 ms<br />

What word did<br />

you see?<br />

Mask: ~ 500 ms


Cognitive Neuroscience of Language

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