The Brain: Structure and Function
The Brain: Structure and Function
The Brain: Structure and Function
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<strong>The</strong> <strong>Brain</strong>: <strong>Structure</strong> <strong>and</strong> <strong>Function</strong><br />
• <strong>The</strong> brain grows to 3 pounds across 20 years<br />
• “Ontology recapitulates phylogeny”<br />
– structures arise in the course of development <strong>and</strong> mirror evolution<br />
• hindbrain: Medulla, pons, cerebellum<br />
• midbrain: superior colliculi, reticular, etc.<br />
• forebrain: higher cognitive functions
Cortical Orientation<br />
• Directions: Lateral/medial, dorsal/ventral, anterior/posterior<br />
• Lobes: Frontal, Occipital, Parietal, Temporal
Localization of <strong>Function</strong><br />
• Franz Gall <strong>and</strong><br />
phrenology<br />
– “faculty psychology”<br />
– assumed<br />
• different parts do<br />
different things (yes!)<br />
• size matters (no!)<br />
• different faculties are<br />
independent (no!)
Neuropsychology<br />
• Broca’s aphasia: Failure to produce speech<br />
• Wernicke’s aphasia: Fluent, nonsensical speech
Motor <strong>and</strong> Somatosensory Cortex
Lateralization<br />
• Left goes to right <strong>and</strong> vice versa<br />
• Language on the left (usually)<br />
– larger left hemisphere <strong>and</strong> h<strong>and</strong>edness<br />
– lateralized <strong>and</strong> bilateralized<br />
• Integration of visual <strong>and</strong> auditory on right<br />
– larger right temporal areas<br />
– geometric puzzles, navigation, faces, sports<br />
• Analytic/Synthetic, Left/Right brained<br />
– but these are simplifications<br />
– each hemisphere can do most things<br />
• split brain patients <strong>and</strong> the corpus callosum
Static Imaging Techniques<br />
(CAT, MRI, <strong>and</strong> PET)
<strong>Function</strong>al Imaging Techniques<br />
• Hemodynamic:<br />
– Positron Emission<br />
Topography (PET)<br />
– functional Magnetic<br />
Resonance Imaging<br />
(fMRI)<br />
• Electrophysiology:<br />
– EEG/ERP<br />
– MEG
Subtraction Technique
Electroencephalography (EEG) <strong>and</strong> Event-<br />
Related Potential (ERP)
Presentation<br />
Sequence<br />
Word Priming<br />
doctor<br />
NURSE<br />
Prime: 10 - 2000 ms<br />
Target: ~ 50 ms<br />
What word did<br />
you see?<br />
Mask: ~ 500 ms
Cognitive Neuroscience of Language