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COBRA Annual Report 2007 - Technische Universiteit Eindhoven

COBRA Annual Report 2007 - Technische Universiteit Eindhoven

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modulation, network coding, adaptation,<br />

equalization, timing recovery, and detection<br />

techniques. Systems-oriented work demonstrates<br />

these techniques in optical storage and wireless<br />

and optical transmission. Commercial impact is<br />

evidenced by many patents.<br />

For optical storage we developed backwards<br />

compatible techniques for future 4 th generation<br />

systems, e.g. for near-minimum-bit-error rate<br />

adaptation [3], 2-dimensional intersymbol<br />

interference cancellation, and characterization of<br />

mixtures of modulation noise and additive noise.<br />

We also developed bit-detection techniques that<br />

optimally handle these mixtures and that use<br />

parity-check codes for significant performance<br />

improvements. In the context of our new Center<br />

for Wireless Technology <strong>Eindhoven</strong>, we reported<br />

the world’s first MIMO channel characterization<br />

techniques in the so-called angular domain, which<br />

admits a simple ray-tracing-like view of the link<br />

between transmit and receive antennas. With<br />

Philips Research we developed innovative agile<br />

transmission strategies that exploit the basic<br />

channel state information that is available in<br />

modern communication standards.<br />

Medical signal processing<br />

This research deals with medical monitoring and<br />

decision-support techniques. It aims at improving<br />

diagnostic capabilities, at reducing risk to the<br />

patient, and at lowering complexity and cost.<br />

Scientifically it focuses on simple dynamic models<br />

of physiology, on efficient parameter-estimation<br />

for these models, on robust spatiotemporal signal<br />

processing in highly nonstationary settings. Crossappointments<br />

ensure a close collaboration with<br />

strategic partners.<br />

Our award-winning cardiovascular quantification<br />

techniques were clinically validated and refined<br />

[4], and were extended to new pathologies (e.g.<br />

prostate cancer) and to the MRI imaging modality.<br />

Our work on fetal monitoring, with the Maxima<br />

Medical Center, has led to a new standard for<br />

suppression of the maternal electrocardioagram,<br />

to an award-winning non-invasive technique<br />

for assessment of intra-uterine pressure<br />

that may replace invasive techniques, to the<br />

word’s first contactless registration of the fetal<br />

electrocardiogram via capacitive electrodes (with<br />

Philips Research), and to a prototype system for<br />

clinical validation of these techniques. Our work on<br />

neurometry has led to a breakthrough in correction<br />

of eye-movement artifacts, by using a camera as<br />

a basis for correction, bringing the ideal of singletrial<br />

analysis a significant step closer [5].<br />

Key publications<br />

1 M.J. Bastiaans and T. Alieva, ‘Classification of<br />

lossless first-order optical systems and the linear<br />

canonical transformation’, J. Opt. Soc. Am. A 24,<br />

<strong>2007</strong>, pp. 1053-1062.<br />

21

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