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Why Vitamin B12 Deficiency Should be on your Radar Screen

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<str<strong>on</strong>g>Vitamin</str<strong>on</strong>g> <str<strong>on</strong>g>B12</str<strong>on</strong>g> <str<strong>on</strong>g>Deficiency</str<strong>on</strong>g><br />

Pretest and Posttest<br />

If you want to receive c<strong>on</strong>tinuing educati<strong>on</strong> credit for<br />

this program, complete this posttest. Please read the<br />

case history and then answer the questi<strong>on</strong>s that follow.<br />

Choose the answer that is most correct for each<br />

questi<strong>on</strong>.<br />

Case<br />

A 60-year-old teacher with a history of hypothyroidism<br />

and gastroesophageal reflux disease (GERD) reports<br />

significant fatigue, hot flashes, and memory difficulty<br />

since her last annual visit. On detailed review of<br />

symptoms, she also admits to irritability, emoti<strong>on</strong>al<br />

lability, decreased appetite, difficulty sleeping, and<br />

occasi<strong>on</strong>al tingling of her fingertips. Her last m<strong>on</strong>thly<br />

period was 2 years ago. She has <str<strong>on</strong>g>be</str<strong>on</strong>g>en following a<br />

vegetarian diet for the past 5 years to try to lose weight.<br />

During the physical examinati<strong>on</strong>, she is alert and<br />

oriented x 3, but tearful at <strong>on</strong>e point during the<br />

interview with an MMSE score of 28 out of 30. There are<br />

no abnormal physical findings.<br />

Her CBC results:<br />

RBC 4.6 (4.2–5.8) 10^6/µL<br />

MCV 90 (78–102) fL<br />

Hgb 15 (12.0–16.0) g/dL<br />

WBC 6.4 (4.3–11.0) 10^3/µL (normal differential)<br />

Plts 312 (144–440) 10^3/µL<br />

Smear shows normocytic, normochromic RBCs<br />

Chemistry results:<br />

Na 139 (136–148) mEq/L<br />

K 4.7 (3.5–5.5) mEq/L<br />

Cl 103 (98–110) mmol/L<br />

BUN 20.0 (9.34–23.35)mg/dL<br />

Cr 1.0 (0.4–1.5) mg/dL<br />

CO2 25 (21–33) mmol/L<br />

Gluc 80 (60–140) mg/dL<br />

GOT 26 (1–32) U/L<br />

GPT 14 (1–30) U/L<br />

AlkPhos 115 (31–121) U/L<br />

61

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