is There Any Evidence-based Medicine for the Very Old?

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COLA II Multivariate predictors of tolerability Advanced age Low LVEF Low DBP OAD present Diabetes present Courtesy of H. Krum 0.45 0.72 0.98 0.97 0.1 1.0 Tolerated worse 1.58 2.0 Tolerated better
% Effect of B<strong>is</strong>oprolol on Mortality in Different Age Subgroups 30 25 20 15 10 5 0 Mortality *** *** > 71 years < 71 years Placebo B<strong>is</strong>oprolol < 71 years > 71 years 0 0.2 0.4 0.6 0.8 1 Hazard ratio (95% CI) Erdmann E et al. Eur J Heart Fail 2001; 3:469
Page 1 and 2: Heart Failure 2005 The octogenarian
Page 3 and 4: Mean Age of the Patients with Heart
Page 5 and 6: Factors Distinguishing HF in the El
Page 7 and 8: Baseline Characteristics of Patient
Page 9 and 10: % of patients 35 30 25 20 15 10 5 0
Page 11 and 12: Probability Non-cardiac Comorbidity
Page 13 and 14: Management of HF in the Elderly: Ge
Page 15 and 16: Pharmacological therapy of heart fa
Page 17 and 18: Drug ACEi Loop diuretics Beta-block
Page 19 and 20: Elderly Age is an Independent Predi
Page 21 and 22: Effects of ACE inhibitors on outcom
Page 25 and 26: BRING UP Reasons for Not Commencing
Page 27: % 100 75 50 25 0 84.3 70- 80 years
Page 31 and 32: Beta-blockers Reduce Mortality also
Page 33 and 34: SENIORS: Baseline Characteristics A
Page 35 and 36: LVEF 35 % > 35 % Age 70-75 y > 75
Page 39 and 40: Drug ACEi Loop diuretics Beta-block
Page 41 and 42: 10 5 0 -5 -10 -15 -20 -25 -30 -35 L
Page 43 and 44: % 40 30 20 10 Lack of effect of age
Page 45 and 46: Randomised Controlled Trial of Card
Page 47 and 48: Randomized Controlled Trial of Spec
Page 49: Efficacy of Disease Management Prog

is There Any Evidence-based Medicine for the Very Old?

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