is There Any Evidence-based Medicine for the Very Old?
is There Any Evidence-based Medicine for the Very Old?
is There Any Evidence-based Medicine for the Very Old?
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Effects of a Multid<strong>is</strong>ciplinary Intervention to Prevent <strong>the</strong><br />
Readm<strong>is</strong>sion of Patients with Heart Failure<br />
(Washington University HF d<strong>is</strong>ease management trial)<br />
• Study group<br />
– 282 patients, selected among 1306<br />
– Mean age 79 ys; female, 65%<br />
– NYHA: 2.4 +1.1; EF: 41+13%<br />
• Randomization<br />
– Intervention vs control groups<br />
• Personnel<br />
– Nurse, dietician, social ass<strong>is</strong>tant,<br />
geriatrician, cardiolog<strong>is</strong>t<br />
• Follow-up<br />
– 90 days<br />
• Results<br />
– n.s. mortality<br />
– hospitalizations<br />
– costs ( $153/month/pt.)<br />
– compliance and quality of life<br />
60<br />
50<br />
40<br />
30<br />
20<br />
10<br />
0<br />
Control<br />
Intervention<br />
n.s.<br />
Mortality<br />
% patients Days/patient<br />
0.03<br />
> 1<br />
0.01<br />
> 2<br />
18<br />
16<br />
14<br />
12<br />
10<br />
8<br />
6<br />
4<br />
2<br />
Hospitalizations<br />
0.04<br />
0<br />
Days/patient<br />
Rich et al., NEJM 1995;333:1190