espcrbulletin - European Society for Pigment Cell Research

Educational programs about melanoma are targeted mainly to Whites. However, little is known
about skin cancer awareness in Hispanics, African Americans and other minorities. This has led
to insufficient screening of most minorities and sometimes to late detection and misdiagnosis.
- Argyriadou S, Makridis D, Lygidakis H, Apazidis G, Gagalis G.
Knowledge and behaviour of tourists towards the sun, as studied in a region of northern
Greece. Rural.Remote.Health 5:367, 2005.
Participants: The sample consisted of 802 travelers from northern European countries, and 726
Greeks.
CONCLUSIONS: Our study showed that skin type is the most important predictor of future
sunburn. Increased susceptibility to sun-induced damage of persons with phototypes I and II
mandates their identification as a target group in all media campaigns.
- Autier P.
Cutaneous malignant melanoma: facts about sunbeds and sunscreen. Expert.Rev.Anticancer
Ther. 5:821-833, 2005.
There is accumulating evidence that sunbed use is associated with melanoma when started before
approximately 30 years of age.
- Bishop AJ, Kosaras B, Hollander MC, Fornace A, Jr., Sidman RL, Schiestl RH.
p21 controls patterning but not homologous recombination in RPE development. DNA
Repair (Amst) 2005.
Following DNA damage, p53 dependent expression of p21 results in a rapid cell cycle arrest. The
results suggest that p21 does not play any role in maintaining overall genomic stability by
regulating homologous recombination frequencies during development.
- Brenner M, Degitz K, Besch R, Berking C.
Differential expression of melanoma-associated growth factors in keratinocytes and
fibroblasts by ultraviolet A and ultraviolet B radiation. Br.J.Dermatol. 153:733-739, 2005.
RESULTS: In keratinocytes, UVB and UVA increased bFGF protein levels up to 2.6-fold. In
fibroblasts, bFGF protein levels were increased 11-64-fold by UVA and 34-61-fold by UVB.
- Chintala S, Li W, Lamoreux ML, Ito S, Wakamatsu K, Sviderskaya EV, Bennett C, Park YM,
Gahl WA, Huizing M, Spritz RA, Ben S, Novak EK, Tan J, Swank RT.
Slc7a11 gene controls production of pheomelanin pigment and proliferation of cultured cells.
Proc.Natl.Acad.Sci.U.S.A. 102:10964-10969, 2005.
Transport of cystine by the plasma membrane cystine/glutamate exchanger xCT is critical for
normal proliferation, glutathione production, and protection from oxidative stress in cultured cells.
- Corre S, Galibert MD.
Upstream stimulating factors: highly versatile stress-responsive transcription factors.
Pigment Cell Res. 2005, 18:337-348.
In melanocytes USF-1 has been implicated as a key UV-activated regulator of genes associated
with pigmentation. This review will focus on general characteristics of the USF-transcription
factors and their place in some regulatory networks.
- Curtin JA, Fridlyand J, Kageshita T, Patel HN, Busam KJ, Kutzner H, Cho KH, Aiba S, Brocker
EB, LeBoit PE, Pinkel D, Bastian BC.
Distinct sets of genetic alterations in melanoma. N.Engl.J.Med. 353:2135-2147, 2005.
- Diffey BL.
Sunscreens and melanoma: the future looks bright. Br.J.Dermatol. 153:378-381, 2005.
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