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Market Capitalization – Big Pharma - Milken Institute

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Up to<br />

6.5 years<br />

Up to<br />

6 years<br />

Up to<br />

4 years<br />

Total Drug Development Time<br />

From Laboratory to Patient<br />

Function US$, Billions Share<br />

Prehuman /Preclinical $11.0 31.9%<br />

Phase I $2.3 6.8%<br />

Phase ll $3.8 11.1%<br />

Phase Ill $8.0 23.3%<br />

Approval $4.1 12.0%<br />

Phase IV $3.7 10.7%<br />

Uncategorized $1.4 4.2%<br />

Total R&D $34.5 100%

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