Ilko K. Ilev, Ph.D. - Washington Academy of Sciences

Single-Mode Optical Fiber
Why the Interest in Fiber-Optic Biomedical Technologies
(2 - 9 µm core-diameter)
Advanced Optical Fiber Features
non-invasive or minimally invasive precise delivery of
non-ionizing laser irradiation
non-invasive or minimally invasive imaging and sensing with
ultrahigh-resolution in micron, sub-micron and nanorange
low attenuation losses at long interaction length (km)
SMF: 3-µm Single hair: 100-µm
small core diameter - micron, sub-micron and nanometer size
flexibility, compactness, scanning potential
Gaussian Laser Beam Intensity Distribution
free of gases, dyes, solvents, immunity to external interference
electro-magnetic passive operation (MRI, X-ray compatible)
near-to-the-theoretical paraxial conditions
optimum collimated/focused laser beam
Fiber Tapered Nanoprobes
(20 nm - 1 µm tip-diameter)
biosensing and nanobiosesing: high sensitivity, large dynamic
range and multiparameter sesnsor measurements
point light source
point light receiver
multimodality endoscopic system: imaging, sensing, diagnostics,
and therapeutics
advantages in imaging/sensing designs