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Density Gradient • Deoxycholic Acid
344
Density Gradient Solution in which the concentration
of a solute changes with distance.
Density Gradient Centrifugation A technique
for fractionation of macromolecules in which a
mixture of macromolecules to be separated are
centrifuged in a density gradient tube. Different
macromolecules sediment at different positions in
the density gradient tube after centrifugation.
Density Gradient Equilibrium Centrifugation
A type of density gradient centrifugation in which
a concentrated salt solution (e.g., cesium chloride)
containing macromolecules to be separated is
ultracentrifuged until the salt achieves its equilibrium
and forms a linear salt gradient. The macromolecules
in the salt density gradient migrate to the
positions where their densities equal those of the
gradient (also called isopycnic density gradient).
Density Marker Bead A colored bead with
known density used for calibrating density gradients.
2′-Deoxyadenosine 5′-Diphosphate (dADP, mol
wt 411) A diphosphate form of the nucleotide of
adenine.
NH 2
N
N
O O
N N
HO P O P O CH 2
O
OH OH
OH
Deoxyadenosine Kinase The enzyme that catalyzes
the following reaction:
ATP + deoxyadenosine ADP + dAMP
2′-Deoxyadenosine 5′-Monophosphate (dAMP,
mol wt 331) A monophosphate form of the
nucleotide of adenine.
Dental Plaque The matrix of microbial cells and
microbiologically produced extracellular polysaccharides
that forms on the tooth surface.
O
N
NH 2
N
N
N
Dentin The chief calcified structure of the teeth
surrounding the inner part of the tooth. It is covered
by enamel on the crown or cementum on the roots.
HO
P O
OH
O
CH 2
OH
Dentinogenesis The formation of dentin of the teeth.
Deossification Removal of the mineral elements
of bones.
2′-Deoxyadenosine (mol wt 251) A deoxyribonucleoside
of adenine.
2′-Deoxyadenosine 5′-Triphosphate (dADP, mol
wt 491) A triphosphate form of the deoxynucleotide
of adenine.
NH 2
N
N
NH 2
N
N
N N
CH 2 OH
O
OH
A deoxyribo-
3′-Deoxyadenosine (mol wt 251)
nucleoside of adenine.
NH 2
N
N
HO
O
P
OH
O
O
P
OH
O
O
P
OH
Referring to co-
5′-Deoxyadenosylcobalamin
enzyme B 12 .
O
CH 2
OH
N
O
N
Deoxyadenylic Acid Referring to the deoxyribonucleotide
of adenine, e.g., dAMP.
Deoxycholic Acid (mol wt 393) A choleretic
agent and a reagent used for solubilization of membrane
proteins.
N
CH 2 OH
O
N
H 3 C
H 3 C
HO
CH 3
H
COOH
OH
HO
H
H
H