MKSAP Neurology Review

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Movement disorders • Parkinson’s Disease [Idiopathic] – Too little DA in Substantia Nigra – FOUR cardinal features • Tremor • Rigidity • Bradykinesia • Postural instability – Should respond to DA agonists • Parkinson’s Plus syndromes do NOT respond to DA therapy
Tremors • Essential – Action tremor – Disappears at rest • Parkinson’s tremor – Tremor at REST – Disappears wit movement • Cerebellar Tremor [RARE] – Worsens as the target is approached – Clinically obvious
Page 1 and 2: MKSAP Neurology Review Daniel L. Me
Page 3 and 4: 2 overriding concepts • Ockham’
Page 5 and 6: Motor system first! [Strength, tone
Page 7 and 8: Central nervous system • Cortical
Page 9 and 10: SENSORY SYSTEM (2 types) • LARGE
Page 11 and 12: 2 nd Step: Sensory system • If pe
Page 13 and 14: Major Neurology Topics • Headache
Page 15 and 16: Headaches • Any “RED FLAG” he
Page 17 and 18: Cluster headaches • Similar patho
Page 19 and 20: Tumor Comparison Infiltrators Displ
Page 21 and 22: Delirium, Dementia, Stupor, Coma Se
Page 23 and 24: Dementia • Do not diagnose until
Page 25 and 26: Stupor and Coma • FOCAL DEFICIT =
Page 27 and 28: Central versus peripheral Central P
Page 29: Movement disorders • BALANCE of A
Page 33 and 34: Some exceptions • Acute dystonic
Page 35 and 36: 1 lesion ≠ Multiple Sclerosis •
Page 37 and 38: Spinal cord disorders • ALWAYS el
Page 39 and 40: Nerve structure • Myelin sheath -
Page 41 and 42: Myelinopathy versus axonopathy •
Page 43 and 44: Epilepsy • A disorder of the cort
Page 45 and 46: Evaluation • Elicit complete hist
Page 47: Treatment exceptions • Juvenile m

MKSAP Neurology Review

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