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Title Increased serum levels of a proliferation-inducing ligand in ...

Title Increased serum levels of a proliferation-inducing ligand in ...

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A.<br />

Blood Eos<strong>in</strong>ophil (number)<br />

5000<br />

4000<br />

3000<br />

2000<br />

1000<br />

E.<br />

BP180 (<strong>in</strong>dex)<br />

50<br />

40<br />

30<br />

20<br />

10<br />

APRIL<br />

BP180<br />

patient 1<br />

250<br />

200<br />

150<br />

100<br />

50<br />

APRIL (ng/ml)<br />

B.<br />

Extent <strong>of</strong> sk<strong>in</strong> lesion (%)<br />

0<br />

100<br />

80<br />

60<br />

40<br />

20<br />

50 100 200 500 1250 2500<br />

APRIL (ng/ml)<br />

BP180 (<strong>in</strong>dex)<br />

0<br />

140<br />

120<br />

100<br />

80<br />

60<br />

40<br />

20<br />

9 77 98 119<br />

Day from disease onset<br />

APRIL<br />

BP180<br />

patient 2<br />

0<br />

18<br />

14<br />

10<br />

6<br />

2<br />

APRIL (ng/ml)<br />

C.<br />

BP180 (<strong>in</strong>dex)<br />

0<br />

150<br />

125<br />

100<br />

75<br />

50<br />

25<br />

50 100 200 500 1250 2500<br />

APRIL (ng/ml)<br />

BP180 (<strong>in</strong>dex)<br />

0<br />

30<br />

20<br />

10<br />

14 529 604 716<br />

Day from disease onset<br />

patient 3<br />

APRIL<br />

BP180<br />

0<br />

80<br />

60<br />

40<br />

20<br />

APRIL (ng/ml)<br />

D.<br />

0<br />

350<br />

50 100 200 500 1250 2500<br />

APRIL (ng/ml)<br />

0<br />

-14 10 58 71<br />

Day from disease onset<br />

0<br />

300<br />

Disease duration (day)<br />

250<br />

200<br />

150<br />

100<br />

50<br />

0<br />

50 100 200 500 1250 2500<br />

APRIL (ng/ml)

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