16th Annual Scientific Meeting - Heart Failure Society of America

Sept. 11
Tuesday
Posters
Posters
Clinical Trials
Posters
Clinical Trials
Sept. 11
Tuesday
Posters
tuesday
189 Evaluation of the Long-Term Effects of AAV1/SERCA2a
Gene Therapy on Clinical Events in Heart Failure
Patients Using a Novel Statistical Model: Results and
Implications for Future Trials
Barry Greenberg 1 , Alex Yaroshinsky 2 , Howard Dittrich 2 , Jeff
Rudy 2 , Krisztina Zsebo 2 ; 1 Cardiology, University of California,
San Diego, CA; 2 Celladon, La Jolla, CA
190 Re-Establishment of SDF-1 Expression through Non-
Viral Gene Therapy Improves Clinical Parameters
through 12 Months in Patients with Ischemic Class III
Heart Failure
Marc S. Penn 1 , Farrell O. Mendelsohn 2 , Gary L. Schaer 3 ,
Warren Sherman 4 , MaryJane Farr 4 , Joseph M. Pastore 5 , Rahul
Aras 5 , Didier Rouy 6 , Ruth Clemens 5 , William Cotts 7 ; 1 Summa
Cardiovascular Institute, Akron, OH; 2 Center for Therapeutic
Angiogenesis, Birmingham, AL; 3 Rush Univ. Medical Center,
Chicago, IL; 4 Columbia Univ. Medical Center, New York, NY;
5
Juventas Therapeutics, Inc., Cleveland, OH; 6 BioCardia,Inc.,
San Carlos, CA; 7 Northwestern Memorial Hosp., Chicago, IL
191 First Human Dosing Experience with TRV027, a Novel
Therapy for Acute Heart Failure
David G. Soergel 1 , Ruth Ann Subach 1 , Jonathan D. Violin 1 ,
Dennis Yamashita 1 , Maxine Gowen 1 , Michael W. Lark 1 ; 1 Trevena,
King of Prussia, PA
192 Evaluating Treatment Efficacy by Multiple Endpoints in
Phase II Acute Heart Failure Clinical Trials: Analyzing
Data Using a Global Method
Hengrui Sun 1 , 2 , Beth Davison 1 , Gad Cotter 1 , Michael
Pencina 3 , Gary Koch 2 ; 1 Momentum Research, Inc., Durham,
NC; 2 Biostatistics, Gillings School of Global Public Health,
University of North Carolina at Chapel Hill, NC; 3 Harvard
Clinical Research Institute, Boston, MA
193 Acute HF in the Elderly: Different Characteristics,
Outcomes and Prognostic Markers: Is It a Different
Disease? Results from the VERITAS Study
Veritas Steering Committee and Investigators 1 ; 1 Momentum
Research Incorporated, Durham, NC
194 Percutaneous Ventricular Restoration Therapy Using
the Parachute Device in Patients with Ischemic Heart
Failure and Dilated Left Ventricles: The U.S. Pivotal
Trial Design
William T. Abraham 1 , Michael Pencia 2 , Serjan Nikolic 3 ,
Thomas Engels 3 , Marco A. Costa 4 ; 1 Division of Cardiovascular
Medicine, The Ohio State University, Columbus, OH; 2 Harvard
Clinical Research Institute, Harvard University, Boston, MA;
3
Cardikinetix Inc., Menlo Park, CA; 4 Division of Cardiology,
Case Western Reserve University, Cleveland, OH
130
195 Noninvasive Monitoring of Pulmonary Congestion
Using a Remote Dielectric Sensing (ReDS) System: A
Prospective Single-Arm Study in Patients Suffering from
Heart Failure
Dan Rappaport 1 ; 1 Sensible-Medical Innovations LTD, Netanya,
Israel
196 Comparison of the Predictive Values of NT-proBNP and
Lung Impedance Measurements in the Course of BNP-
Guided Treatment of CHF Patients
Michael Shochat 1 , Avraham Shotan 1 , Mark Kazatsker 1 , Aya
Asif 1 , Iris Dahan 1 , Ilia Shochat 1 , Yaniv Levy 1 , David Blondheim 1 ,
Simcha Meisel 1 ; 1 Cardiology, Hillel Yaffe Heart Institute, Hadera,
Israel
197 Short-Term Add-On Therapy with Angiotensin Receptor
Blocker for End-Stage Inotrope-Dependent Heart
Failure Patients: B-Type Natriuretic Peptide Reduction
in a Randomized Clinical Trial
Marcelo E. Ochiai 1 , Euler O. Brancalhao 1 , Raphael S. Puig 1 ,
Kelly N. Viera 1 , Marcelo V. Lima 1 , Juliano N. Cardoso 1 ,
Antonio P. Barretto 1 ; 1 Cotoxo Hospital, Heart Institute(INCOR),
University of Sao Paulo, SP, Brazil
Cardiovascular Pharmacology
204 Activation of Heme-Free Soluble Guanylate Cyclase with
Cinaciguat Has Beneficial Cardiorenal Actions When
Added to Furosemide in Experimental Heart Failure
Guido Boerrigter 1 , Elizabeth C. Costello 1 , Alessandro
Cataliotti 1 , Harald Lapp 2 , Johannes-Peter Stasch 3 , John C.
Burnett 1 ; 1 Cardiovascular Diseases, Mayo Clinic, Rochester, MN;
2
Helios-Clinic, Erfurt, Germany; 3 Bayer Schering Pharma AG,
Wuppertal, Germany
205 Sustained Delivery of a Novel Natriuretic Peptide for
Three Weeks with In Situ Polymer Precipitation Delivery
System
Soo G. Lim 1 , Syed Ameenuddin 2 , John C. Burnett, Jr 2 , Subbu
S. Venkatraman 1 , Horng H. Chen 2 ; 1 School of Material Science
and Engineering, Nanyang Technological University, Singapore,
Singapore; 2 Cardiorenal Research Laboratory, Mayo Clinic,
Rochester, MN
206 Subcutaneous Deliver of M-ANP in Conscious Canines:
An Innovative Designer Guanylyl Cyclase A Receptor
Activator for Cardiovascular Disease
Paul M. McKie 1 , Alessandro Cataliotti 1 , Tomoko Ichiki 1 ,
Horng H. Chen 1 , S. Jeson Sangaralingham 1 , John C.
Burnett 1 ; 1 Cardiorenal Research Laboratory, Division of
Cardiovascular Disease, Mayo Clinic, Rochester, MN
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tuesday