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GSK - Global Manufacturing Services - Brochure

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A CURE FOR THE<br />

ILL-INFORMED.


CONTENTS<br />

A warm welcome 1<br />

An overview of GMS 2<br />

An expanse of opportunity 3<br />

Working together 4-6<br />

A product in profile 7<br />

Acting responsibly 8<br />

The people behind the place 9-10<br />

Training & development and accreditation 11<br />

Rewards and recognition 12<br />

The details of the programme 13<br />

Next steps 14<br />

Dear Graduate<br />

I am delighted to share with you the tremendous<br />

opportunities we have for engineering and science<br />

graduates working within our <strong>Global</strong> <strong>Manufacturing</strong><br />

and Supply (GMS) business in <strong>GSK</strong>. Let me start by<br />

sharing some personal details; having completed a<br />

PhD in Organic Chemistry, my career at <strong>GSK</strong> started<br />

in 1991 supporting the introduction of a range of new<br />

products to our Singapore <strong>Manufacturing</strong> Facility.<br />

Since then I’ve worked across a number of areas<br />

ranging from synthetic chemistry, fermentation science<br />

to formulation science and manufacturing technology.<br />

My role has required me to work in global teams,<br />

across many different cultures and to travel extensively<br />

across four continents.<br />

Our scientists, engineers and technologists work in<br />

close partnership with their colleagues in R&D to<br />

ensure the processes we design and industrialise are<br />

safe, robust, cost-effective and environmentally<br />

friendly. We have integrated key scientific disciplines<br />

to ensure the manufacturing process and related<br />

technology is designed to enhance our control,<br />

ensuring every dose to the patient has quality built-in<br />

at the onset. The technical work environment within<br />

manufacturing now comprises a ‘High Performing<br />

Team’, where disciplines such as synthetic or<br />

formulation science are integrated with pharmaceutical<br />

engineering, material sciences and advanced statistical<br />

analysis to better support the effective scale-up and<br />

industrialisation of our processes.<br />

My career has been varied, exciting, sometimes<br />

daunting, but always enjoyable. I regard myself as<br />

a scientist who comes into work and still manages<br />

to learn something new every day. Knowing that my<br />

work helps people to do more, feel better and live<br />

longer is personally very motivating.<br />

I hope this brochure will serve to educate you, as<br />

graduates, to make better informed decisions about<br />

your career choice.<br />

Kind regards<br />

Bernadette<br />

GMS Technical Head<br />

1


GLOBAL MANUFACTURING AND SUPPLY<br />

(GMS)<br />

We’re the part of <strong>GSK</strong> that leads the rapid<br />

commercialisation of our products and enables<br />

our people to shape the world around them. Our<br />

global network uses a variety of processes and the<br />

latest technology to deliver four billion packs of<br />

medicines and healthcare products a year to<br />

patients and customers.<br />

As a result, our scientists and engineers are applying<br />

their talent in ways they never thought possible.<br />

They collaborate with other areas of the business,<br />

such as R&D and Sales & Marketing, to ensure the<br />

smooth and rapid transition of their newly<br />

developed products into full-scale manufacture.<br />

Thanks to them, we deliver a consistent supply of<br />

high-quality products right across the world.<br />

Our success is down to technical and scientific<br />

excellence, as well as the interdisciplinary strengths<br />

of our team across all our supply divisions. Our<br />

teams, which include scientists, engineers,<br />

statisticians, production managers, and<br />

chemometricians, are achieving results that are at<br />

once immediate, highly visible, and save lives.<br />

Together, they make up the four main parts of GMS<br />

– all of which you can learn more about here.<br />

Primary Supply<br />

Ensuring the faultless supply of high-quality bulk<br />

active ingredients, Primary Supply plays a critical<br />

role in supporting the commercial ambition of <strong>GSK</strong>.<br />

It does this by supporting the introduction of new<br />

products and the secure supply of existing<br />

products. It is continually driving improvements<br />

in technologies and processes to improve our<br />

performance and our cost-competitiveness.<br />

This division works closely with our R&D teams,<br />

particularly our chemical development and<br />

pharmaceutical development functions. These<br />

areas provide Primary Supply with the chemical<br />

entities, formulations, test methods and<br />

manufacturing processes that GMS uses<br />

in production.<br />

2<br />

New Product & <strong>Global</strong> Supply<br />

Working closely with R&D, this division ensures that<br />

the appropriate technical competencies exist to<br />

support the quick and successful introduction of<br />

new products. It also ensures the supply of key,<br />

globally distributed <strong>GSK</strong> brands. At the same time,<br />

the division is the focal point for developing new<br />

secondary manufacturing technologies for <strong>Global</strong><br />

<strong>Manufacturing</strong> and Supply.<br />

Consumer Healthcare<br />

Consumer Healthcare offers the capability for rapid<br />

new product introduction. It delivers high-quality<br />

products in a competitive business that works to<br />

much shorter timeframes than pharmaceuticals.<br />

While new technologies become a fundamental<br />

platform for lowering costs and providing flexibility,<br />

at present the focus is on automation and capacity<br />

projects – driving ‘design for manufacture’<br />

initiatives with R&D. Its strengths are the oral<br />

healthcare, healthcare, over-the-counter medicines,<br />

and nutritional healthcare product sectors. Some of<br />

the key products which you’ll be familiar with are<br />

Lucozade, Ribena, Horlicks, Panadol, Aquafresh<br />

and Sensodyne.<br />

Regional Pharmaceutical Supply<br />

Here the focus is on several key activities: the<br />

supply of products that are key in one or more<br />

regions; the supply of products that are important<br />

in a particular market; and the tailoring of<br />

packaging to meet specific local requirements.<br />

In addition to other customer-driven activities,<br />

the Regional Pharma team is key to reducing<br />

costs so that <strong>GSK</strong> can compete more effectively<br />

in all its markets.<br />

LET US<br />

ENLIGHTEN YOU.


WE<br />

understand<br />

that there are some<br />

GRADUATES who don’ t know<br />

a great deal about GLOBAL<br />

<strong>Manufacturing</strong> and Supply, which<br />

is fi ne. But we do worry about the<br />

ones who aren’t interested in<br />

FINDING OUT MORE. They’ve no idea<br />

how much they’re missing out on.<br />

They’ll never fully appreciate the<br />

BREADTH OF ENGINEERING and<br />

SCIENTIFIC OPPORTUNITIES we<br />

offer, or the VARIETY OF PROJECTS<br />

and PROGRAMMES our people<br />

get involved in. Nor will they<br />

realise just how many DIFFERENT<br />

SPECIALISTS get involved in<br />

developing our products and so<br />

how many experts they could<br />

learn from. All of which is fi ne.<br />

After all, IGNORANCE IS<br />

BLISS, and not knowing<br />

will mean graduates will<br />

be spared the frustration<br />

and irritation of missing<br />

out on a WORLD-<br />

CLASS technical<br />

career that could<br />

lead almost<br />

ANYWHERE.<br />

SOME GRADUATES<br />

DON’T HAVE A CLUE.<br />

Not<br />

knowing will prevent<br />

THE AGONY of realising<br />

here, for a brief fleeting<br />

moment, was a CAREER OPPORTUNITY<br />

OF A LIFETIME; a career opportunity<br />

that offers SUPPORT and STIMULATION<br />

in equal measure, and through<br />

a lack of awareness, they let it<br />

slip away. Let us just hope<br />

they never hear about it.<br />

SSSH, MUM’S THE<br />

WORD.<br />

Chemometrics<br />

Materials Science<br />

(device technology)<br />

Fermentation<br />

Science<br />

Process Control<br />

& Automation<br />

Chemical (Process)<br />

Engineering<br />

Production<br />

Management<br />

Fluid Dynamics/<br />

Rheology<br />

Statistics<br />

Granular Materials<br />

(bulk powder handling)<br />

Extraction<br />

Science<br />

Project<br />

Management<br />

Instrumentation<br />

Engineering<br />

Microbiology<br />

BREADTH OF OPPORTUNITY<br />

Bio processing<br />

Microbiology<br />

Process Development<br />

Chemistry<br />

Packaging<br />

Technology<br />

Physical Properties<br />

Formulation Science<br />

& Pharmacy<br />

Mechanical<br />

Engineering<br />

Physical Chemistry<br />

(incl. Particle Science)<br />

Maintenance<br />

Engineering<br />

Electrical<br />

Engineering<br />

Analytical Development<br />

Chemistry<br />

Calibration<br />

Engineering<br />

Process Measurement/<br />

Process Analytics<br />

Reliability<br />

Engineering<br />

Scale-up<br />

Chemistry<br />

Utilities<br />

Engineering<br />

Process<br />

Technology<br />

Mathematical<br />

Modelling<br />

Engineering Science Engineering or Science<br />

Throughout this brochure, we hope to give you an idea of the type of roles you could have during a<br />

technical career with <strong>GSK</strong>. Clearly, some roles require a specific background or degree discipline while others<br />

are open to both scientists and engineers. Due to the scope and changing nature of both our business and<br />

our products, every role isn’t covered in depth in this brochure. However, the roles shown should give you<br />

some idea of the breadth of opportunity available and areas you may be interested in.<br />

3


MULTI-DISCIPLINARY TEAMS<br />

Let’s take a closer look at how everything fits<br />

together in the case of a vitally important <strong>GSK</strong><br />

product – the Seretide Accuhaler.<br />

So what exactly is the Seretide<br />

Accuhaler?<br />

Seretide Accuhaler is what we call a maintenance<br />

medicine. Patients use it as a regular medication for<br />

breathing-related complaints. For instance, asthma<br />

sufferers and people with Chronic Obstructive<br />

Pulmonary Disease (COPD) use the Seretide<br />

Accuhaler. COPD sufferers will use the Seretide<br />

50/500 Accuhaler for the treatment of symptoms<br />

and to prevent exacerbations.<br />

Let’s get a little technical and see what’s involved<br />

in the drug. Seretide contains two medicines:<br />

salmeterol and fluticasone propionate. Salmeterol is<br />

a long-acting bronchodilator. Broncholdilators help<br />

the airways in the lungs to stay open, which makes<br />

it easier for air to get in and out. Fluticasone<br />

propionate is a corticosteroid which treats the<br />

underlying inflammation in the lungs.<br />

4<br />

And what goes into it?<br />

Developing and combining these medicines is only<br />

one aspect of bringing the product to market.<br />

What gives Seretide Accuhaler its complexity is the<br />

fact that it has two elements: a pharmaceutical<br />

compound (combination therapy) and the<br />

patented inhalation device through which the<br />

product is delivered. And it’s the added element<br />

that means the product represents an impressive<br />

feat of engineering as well as the latest thinking in<br />

modern pharmacology.<br />

More specifically, the compound is housed in a<br />

series of blisters on a sealed strip in a coil inside the<br />

accuhaler. Activating the device pops the seal and<br />

then the act of inhaling draws the compound down<br />

inside the lungs. Sounds simple? Well, unfortunately<br />

it isn’t. There are thousands of variables to consider.<br />

The powder has to stay dry. The seal has to pop.<br />

The particles of compound have to be the right size<br />

to be drawn down into the right part of the lung.<br />

And when the device is activated for the last time,<br />

the compound has to flow through it in exactly the<br />

same way it did the first time. In addition, each of<br />

the 100 million+ devices we make each year need<br />

to perform in an identical and consistent way. Small<br />

wonder, then, that our multi-disciplinary teams<br />

combine such a breadth of expertise and work so<br />

closely together.<br />

NO<br />

ONE GETS<br />

LEFT ON ONE<br />

SIDE AT <strong>GSK</strong>.<br />

As you’ll fi nd out<br />

over the next few<br />

pages, bringing<br />

our products<br />

to market IS A TEAM EFFORT. We need<br />

to combine the EXPERTISE, ENERGY<br />

and ENTHUSIASM of SCIENTISTS and<br />

ENGINEERS from a host of backgrounds<br />

to meet the exceptional standards of<br />

QUALITY, INTEGRITY<br />

and CONSISTENCY<br />

that inform all our<br />

healthcare products.<br />

So EXPERTISE AND<br />

KNOWLEDGE GET<br />

SHARED, IDEAS ARE TRANSFERRED ACROSS<br />

DEPARTMENTS AND SUCCESSES ARE<br />

CELEBRATED TOGETHER AS A TEAM. This<br />

collaborative approach makes for an IMMENSELY<br />

REWARDING WAY OF WORKING, as you’ll<br />

develop a helicopter view of product development<br />

and get to<br />

work with<br />

SOME OF THE<br />

BEST PEOPLE<br />

IN THEIR<br />

FIELD.<br />

SEE THE<br />

BIG PICTURE.


PRE-LAUNCH<br />

On the road to launch, Seretide faces a raft of<br />

challenges. Typically, our products will complete<br />

over 30 phases of tests in the ten or so years they are<br />

in development, and Seretide is no exception. At this<br />

stage, we will prove to the regulators in this country,<br />

the US and elsewhere that we have impeccable<br />

quality, integrity and effectiveness credentials.<br />

Particle Scientists<br />

Our Particle Scientists help optimise the process by<br />

looking at the way the compound’s particles will<br />

behave. They will model the rheology of our<br />

powders, final particle forming stages, and particle<br />

size reduction techniques.<br />

Process Engineers<br />

The focus here is micronisation and blending,<br />

producing exact particle sizes so they’re able<br />

to penetrate the right areas of the lungs.<br />

They will focus in particular on the optimisation<br />

of the key transformation stages of our<br />

manufacturing process.<br />

Chemometricians and Statisticians<br />

Our Chemometricians and Statisticians<br />

support the experimental process with<br />

mathematical statistics and data analysis<br />

looking for multi-variate relationships<br />

between the various components. In<br />

addition they will be looking for patterns<br />

within our data and ensuring our analysis<br />

is always best practice.<br />

Regulatory Affairs<br />

Our regulatory experts help ensure<br />

Seretide’s therapeutic value is<br />

unquestioned, focusing on consistency,<br />

process control and quality.<br />

The principal challenges are around maximising<br />

yields (ensuring waste is kept to a minimum),<br />

protecting against contamination, streamlining<br />

our processes and improving our equipment’s<br />

effectiveness. Answering these questions calls for an<br />

array of specialist talent from different disciplines:<br />

Packaging Engineers<br />

These experts find answers to the questions around<br />

supplying the product and how it will be packaged.<br />

Control (Automation)<br />

Improving the production process of Seretide is the<br />

brief here. The emphasis is on process control and<br />

process measurement by working closely with the<br />

Chemometricians and Statisticians.<br />

Analytical Chemists<br />

Involved throughout the process, our Analytical<br />

Chemists look at the aerosolisation of the dry<br />

powder formulation, geometric particle sizes and<br />

molecular properties of the compounds and<br />

anticipate how they will behave. They will also be<br />

involved in modelling impurities in the products<br />

and batch-to-batch consistency.<br />

Validation Engineers<br />

The measure of our success is whether our<br />

medicines perform as promised. Validation<br />

Engineers make this their focus, drawing on<br />

data modelling techniques.<br />

Product Technologists<br />

They are involved in and support each and every<br />

stage of the process and every member of the<br />

multi-disciplinary team. They typically work on<br />

the formulation and the device, capturing and<br />

analysing data from key experimental programmes<br />

to optimise the formulation and device performance.<br />

Formulation Scientists and Pharmacists<br />

As the name suggests, our Formulation Scientists<br />

and Pharmacists help shape the formulation of<br />

Seretide to deliver a combination product rather<br />

than the more traditional single active ingredient<br />

product. They take its development from an Active<br />

Product Ingredient to a medicinal compound.<br />

5


POST-LAUNCH<br />

Successfully bringing the product to market is<br />

far from the end of the development process.<br />

It represents the beginning of a new phase and<br />

the opening up of a whole new set of scientific,<br />

engineering and commercial challenges around<br />

the mass production and supply of the product.<br />

At this stage, our thinking is concentrated on<br />

improving the overall effectiveness of our<br />

equipment, on the scientific and engineering<br />

Mechanical and Automation Engineers<br />

Our Mechanical Engineers’ attention turns to the<br />

challenge of assembly post-launch e.g. the insertion<br />

of the foil strip containing the pharmaceutical<br />

active ingredient into the device, completion of the<br />

assembly of the device (we produce one million a<br />

week), and checking the mechanical functionality so<br />

that it works when it arrives in the patient’s hands.<br />

Our Automation Engineers will work alongside the<br />

Mechanical Engineers and focus on improving<br />

equipment effectiveness through automation.<br />

Chemometricians and Statisticians<br />

By analysing and interpreting data, our<br />

Statisticians help improve our production<br />

process and push us towards operational<br />

excellence. Our Chemometricians will be<br />

focusing on a multi-variate operating space –<br />

how the different parameters come together<br />

to give a robust and repeatable performance.<br />

These challenges absorb our Chemometricians<br />

and Statisticians and underpin their data analysis<br />

at this stage to drive continuous improvement.<br />

Process Engineers<br />

Our Process Engineers work to find answers to the<br />

processing issues surrounding the move to mass<br />

production of the Seretide Accuhaler. They will be<br />

working very closely with the Chemometricians<br />

and Statisticians to optimise our commercial scale<br />

manufacturing processes.<br />

6<br />

demands of scaling-up production from batches<br />

of a few kg of the pharmaceutical compound to<br />

batches in excess of 50kg, and from 100 devices to<br />

batches of 50,000. A key focus of the post-launch<br />

stage is the minimisation of waste and maximisation<br />

of yields. Once again, our success depends on<br />

drawing together experts from many different<br />

disciplines into an integrated, flexible and<br />

patient-focused team:<br />

Regulatory Affairs<br />

The team’s brief is to ensure we meet our regulatory<br />

obligations and Seretide’s quality and integrity<br />

remain unchanged as we enter mass production<br />

and supply of the product.<br />

Device Technologists<br />

Making sure the accuhaler maximises delivery<br />

of the compound is the focus for our Device<br />

Technologists. They will be looking at improving<br />

the tolerances on all our device components,<br />

working closely with the suppliers to ensure the<br />

device function is robust and repeatable.<br />

Analytical Chemists<br />

Our Analytical Chemists and Analytical<br />

Development Chemists help produce larger<br />

quantities of Seretide without compromising its<br />

quality. They will be focused on improving their<br />

analytical methods and trending product<br />

performance (aerosolisation, drug content, particle<br />

size, impurities).<br />

Microbiologists<br />

Our team of Microbiologists analyse micro-organisms<br />

from the production environment and focus on<br />

preventing contamination throughout product<br />

manufacture. They will work closely with the<br />

suppliers of raw materials to ensure that their<br />

processes are robust and do not pose any<br />

microbiological risk to the Seretide product.


NOT FOR THE<br />

SIMPLE-MINDED.<br />

At <strong>GSK</strong>, we pride ourselves on being able to make<br />

the complex appear simple. Take Aquafresh<br />

toothpaste, for instance.<br />

Have you ever wondered how the stripes are<br />

squeezed into a tube?<br />

Putting the product together is like following a<br />

recipe. Each ingredient must be added and mixed<br />

in a way that can be repeated on a massive scale.<br />

Powders have to be mixed with liquids and blended<br />

so that the toothpaste is uniform and lump-free<br />

and, crucially, air has to be kept out of the mixing<br />

process so that the paste doesn’t become foam,<br />

which requires careful design of the mixing process.<br />

The fillers can only accurately measure the<br />

correct amount of paste for each stripe if<br />

the paste is incompressible. The fillers are like<br />

big syringes, so if the toothpaste has air in it, the<br />

product will expand and contract as it is sucked<br />

into the filler and squeezed out into the tube.<br />

Differences in the air content will mean that<br />

the filled weight in the tube varies from one tube<br />

to another.<br />

The tubes require gentle handling especially when<br />

they are empty so that they are not dented or<br />

marked. They are fed at high speed into the filling<br />

machine and filled with the nozzle at the bottom<br />

rather than through the spout. The flat end of the<br />

tube is then heat sealed so that the tubes don’t burst<br />

if someone sits on them in your sponge bag.<br />

There is a patented process developed for filling<br />

stripy toothpaste at <strong>GSK</strong>. The filling machines<br />

have special nozzles that reach down into the tubes<br />

and fill them up like a stick of rock. As the tube fills<br />

up, the nozzles retract to avoid disturbing the<br />

stripes already in there. In cross section, the filled<br />

tube looks like there are six different pie sections,<br />

two of each colour. When the paste is squeezed<br />

onto your brush, the stripes remain – even at the<br />

bottom of the tube – because the toothpaste is<br />

of an even viscosity all the way down.<br />

To check on the quality of the stripes in the<br />

tube, we freeze the filled tube in liquid CO2<br />

and then saw it in two. (If the tube is cut when<br />

unfrozen, the stripes in the tube smear.) Needless<br />

to say, setting up the filling machines correctly is a<br />

very skilled job. Why? Because we’ll be relying on<br />

that machinery to help just one site produce 760<br />

tubes per minute – every minute, every hour,<br />

every day.<br />

7


CORPORATE RESPONSIBILITY<br />

Nowadays, corporate responsibility crops up in all<br />

kinds of places. Some of them make sense, while<br />

other topics might seem to sit better under a<br />

different heading. But actually corporate<br />

responsibility is simply about doing what’s right.<br />

The things we all instinctively know to be right.<br />

So we drew together some statistics about our<br />

corporate responsibility, and we thought you<br />

could decide whether they fit with your idea of<br />

responsible behaviour.<br />

900m<br />

That's the number of donated treatments to date<br />

of <strong>GSK</strong>’s albendazole. This helps break the<br />

transmission of mosquito-borne parasitic disease<br />

lymphatic filariasis (elephantiasis) affecting over<br />

120 million people. Working with the World Health<br />

Organization and other partners, we aim to<br />

eliminate the disease by 2020. <strong>GSK</strong> provides<br />

financial support, medicines, time and equipment<br />

to help improve health and education in underserved<br />

communities around the world. Our<br />

programmes are innovative, sustainable, and<br />

benefit those most in need.<br />

268m<br />

Last year we also supplied this many tablets of<br />

the HIV/AIDS medicines Combivir and Epivir to<br />

developing countries. (This includes 183 million<br />

tablets supplied by licensed generic manufacturers.)<br />

£282m<br />

That was the value of our community investment<br />

in 2007.<br />

8<br />

37 %<br />

That’s the percentage of managers across the<br />

<strong>GSK</strong> businesses that are women. (And women<br />

account for 22 per cent of people in senior<br />

management roles.)<br />

We’re also cutting our waste<br />

For example, the Nutritionals factory at<br />

Rajahmundry in India, which produces the<br />

Horlicks range, is located in an area badly affected<br />

by droughts. Several years ago they set up ‘Project<br />

Preserve’ to ensure effective waste management<br />

and to preserve natural resources, especially fresh<br />

water which comes from bore holes. A target<br />

was set to cut water consumption by 20 per cent.<br />

By involving staff across the site, water points<br />

were rationalised, pressure was reduced, and<br />

cooling water was recycled – saving both water<br />

and energy. The amount of water recovered from<br />

steam improved by nearly 75 per cent. Wastewater<br />

is treated in the effluent treatment plant, and then<br />

stored in a lagoon that contains fish. The fish and<br />

locally grown vegetables are used to feed the site’s<br />

1200 employees. Treated water is also used to flush<br />

the toilets.<br />

As a result of these initiatives, Rajahmundry achieved<br />

a sustained reduction in the amount of fresh water<br />

it consumes, of nearly 50 per cent during the<br />

period 2001-2005 – more than double its target.<br />

Reusing other wastes has also saved money, for<br />

instance 95 per cent of solid waste is treated by<br />

bio-composting, avoiding the cost of incineration.<br />

YOU’VE A BRAIN THE<br />

SIZE OF A PLANET;<br />

US TOO.


There’s<br />

no better<br />

advert for GLOBAL<br />

MANUFACTURING<br />

and Supply than<br />

OUR PEOPLE. We could<br />

write volumes about our<br />

OPPORTUNITIES and the<br />

REWARDING COMPLEXITY and<br />

challenge of our work, but the most<br />

compelling evidence for all these<br />

qualities are the experiences of<br />

our people. From their ACHIEVEMENTS<br />

and PERSONAL STORIES you can<br />

uncover what it’s like to work here,<br />

what sort of PROJECTS you could<br />

become involved in and the<br />

kind of CHALLENGES you’ll<br />

face. As you’ll discover, ours is<br />

A TEAM-BASED, COLLABORATIVE<br />

CULTURE that encourages<br />

IDEAS, REWARDS INNOVATION<br />

and PROMOTES<br />

INITIATIVE.<br />

The<br />

PERFECT<br />

environment, in fact, to blaze<br />

a BRILLIANT CAREER PATH for<br />

others to follow. So without<br />

further ado, let’s introduce you<br />

to some of our BRIGHTEST<br />

STARS, and fi nd out what<br />

they’ve got to say<br />

ABOUT THEIR TIME<br />

AT GMS.<br />

HARD ACTS<br />

TO FOLLOW.<br />

CHEMISTRY<br />

Denise<br />

Physical Scientist, Process Engineering<br />

Education<br />

National University of Ireland, Galway:<br />

First Class Honours, Chemistry<br />

“I’m in my second year of the programme, working<br />

in New Product and <strong>Global</strong> Supply. My group is<br />

involved in advanced material characterisation,<br />

providing physical science support for the<br />

development of new products and investigating<br />

issues with existing materials. The day-to-day role<br />

varies greatly as I work on a number of projects at<br />

any one time. Currently I’m investigating<br />

processing issues with a variety of products in both<br />

respiratory and tablets, and creating a library of<br />

physical data on all products on our site. I’m also<br />

assessing existing technology in terms of<br />

capabilities and looking at new technologies to<br />

measure particular material properties. I am based<br />

in an office but I spend time in a laboratory, in an<br />

R&D facility and in manufacturing environments.<br />

I’ve also been part of a team in Primary Supply that<br />

increased the yield of a product that was previously<br />

on a worldwide risk register. While in that role, we<br />

reached a year of no failures where previously there<br />

was a very high frequency of failing batches.<br />

I’ve already had some valuable training including<br />

tabletting technology, mechanical, physical and<br />

chemical characterisation of powders, and lean<br />

manufacturing and Six Sigma. I have gained<br />

primary and secondary processing knowledge,<br />

advanced material characterisation skills, and<br />

improved my communication, organisation and<br />

problem-solving skills. My mentors and my current<br />

manager have all had a big impact on me. They<br />

have all been particularly good in helping me with<br />

decisions about future placements.<br />

I want to further progress one of the two roles I<br />

have enjoyed so far on the graduate programme.<br />

I’m getting to do a variety of different jobs as a<br />

chemist and seeing different parts of the business.<br />

“I don’t think people realise how much science<br />

there is in GMS.”<br />

Denise<br />

September 2006, Process<br />

Owner/Technical Support,<br />

GMS Worthing.<br />

Nicola<br />

September 2002,<br />

Statistician, GMS Ware.<br />

Gregor<br />

July 1997, Process<br />

Engineer, GMS Irvine.<br />

September 2003, Senior<br />

Statistician, GMS Ware.<br />

May 1999, Process<br />

Engineer, GMS Montrose.<br />

And I would say to others considering the<br />

programme that I don’t think people realise how<br />

much science there is in GMS – people think that<br />

it only exists in R&D but they are mistaken!”<br />

Denise joined in 2006, initially in Regional Pharma<br />

Supply, currently works in NP&GS, and will start her<br />

third and final year on the programme in January.<br />

September 2007, Physical<br />

Scientist, GMS Ware.<br />

May 2001, <strong>Manufacturing</strong><br />

Improvement Leader,<br />

GMS Montrose.<br />

September 2004, Senior<br />

Technical Engineer, <strong>GSK</strong><br />

<strong>Global</strong> Head Office.<br />

Feb 2002, Senior Project<br />

Engineer, <strong>GSK</strong> <strong>Global</strong><br />

Head Office.<br />

9


OTHER SCIENCE & ENGINEERING<br />

Nicola<br />

Technical Manager – Engineering, Technology &<br />

Capital Management<br />

Education<br />

University of Newcastle upon Tyne: MEng (Hons)<br />

Chemical & Process Engineering<br />

University of Newcastle upon Tyne:<br />

Postgraduate research in the Foresight Centre for<br />

Process Analytics & Control Technology<br />

“I changed my mind a lot when I was younger<br />

but I was always interested in Maths and Science.<br />

My first motivator was attending the Women in<br />

Science & Engineering Convention during A-levels.<br />

That sparked my interest and gave me ideas<br />

about engineering.<br />

But my career wasn’t planned, I just naturally<br />

progressed into my current role because of my<br />

technical interests and because I was open to<br />

opportunities. In fact I chose my degree as it was<br />

multi-disciplined and not restricted to one area.<br />

And probably my most significant career milestone<br />

was moving to an above-site role because it has<br />

given me the chance to work on a broad range of<br />

technical projects with a variety of disciplines. As<br />

I work across functions at <strong>GSK</strong>, it means I meet a<br />

broader set of people to learn about different types<br />

of roles and possibilities.<br />

So I would recommend taking the opportunities that<br />

come your way. A benefit of working at <strong>GSK</strong> is that<br />

you can be flexible and open to trying new things<br />

out simply because there are so many options.”<br />

Nicola joined <strong>GSK</strong> as a Statistician in 2002 and is<br />

currently a Technical Manager at <strong>GSK</strong>’s <strong>Global</strong> Head Office.<br />

Feb 2004, Technical<br />

Manager, <strong>GSK</strong> <strong>Global</strong><br />

Head Office.<br />

10<br />

May 2007, Technical Manager,<br />

<strong>GSK</strong> <strong>Global</strong> Head Office.<br />

April 2005, <strong>Manufacturing</strong><br />

Technology Manager, GMS<br />

Puerto Rico.<br />

PROCESS ENGINEERING<br />

Gregor<br />

Engineering Director – GMS China<br />

Education<br />

Institution of Chemical Engineers: CEng MIChemE<br />

University of Paisley: BEng (Hons)<br />

“My industrial placement at university crystallised<br />

the types of roles I wanted to be in. I have,<br />

however, gone full circle from technical roles into<br />

general management roles and then back to<br />

technical roles. This demonstrates the number of<br />

opportunities a technical background can offer.<br />

I have always been career-orientated and I am<br />

structured and organised in my planning. So I took<br />

the time to produce my own career map – to set<br />

goals for the future – and I found a mentor who<br />

offered me advice and opportunities. I would<br />

recommend assessing your competencies through<br />

the development planning process to identify<br />

where you need development; then base-line<br />

yourself against positions you aspire to. It is<br />

sometimes viewed cynically but is actually a very<br />

powerful tool that provides definition in your career.<br />

To provide wider options I would also strongly<br />

advocate taking a second/third language. I would<br />

also recommend travelling. It helps you grow and<br />

develops you into a more rounded person. I would<br />

also advise moving around and across the business.<br />

This gives you experience and expands your<br />

potential for discovering opportunities.<br />

For example, the work I did in Puerto Rico has been<br />

significant on both a management and personal<br />

level. I had to move to a different country, so I was<br />

thrust into a new culture and language, which<br />

presented challenges – but was hugely rewarding.<br />

During this time, I was in an environment which was<br />

undergoing a lot of change at a very fast pace with<br />

a lot of pressure. Overall it was just a phenomenal<br />

experience and one that I will never forget. It also<br />

proved a solid foundation for my current role where<br />

I am responsible for engineering operations at<br />

GMS's three manufacturing sites in China. In<br />

addition to engineering service provision, my role<br />

includes building technical competency at each site<br />

and delivering a capital investment programme that<br />

is aligned to their business objectives.<br />

“I found a mentor who offered me advice<br />

and opportunities.”<br />

July 2006, Engineering<br />

Remediation Team Leader,<br />

GMS Puerto Rico.<br />

Nov 2007, GMS Business<br />

Change Project Member,<br />

<strong>GSK</strong> <strong>Global</strong> Head Office.<br />

As I have said, I am very career-orientated and so I<br />

may at some stages have let my personal life suffer.<br />

But I wouldn’t change any of the decisions I have<br />

made. It is essential to look objectively from both your<br />

professional life and personal life and decide where<br />

you want to be – different people have different<br />

aspirations. Sometimes a sacrifice in one area may<br />

have to be made to be ultimately better off.”<br />

Gregor joined in 1997 as a Process Engineer and has held<br />

a number of different roles. He is currently an Engineering<br />

Director for GMS in China.<br />

May 2008, currently an<br />

Engineering Director,<br />

GMS China.


YOU’VE A LOT<br />

TO LEARN.<br />

TRAINING & DEVELOPMENT<br />

We see your development comprising four main<br />

parts, which will be tailored to meet your needs.<br />

The bullet points below give you a very brief<br />

view of where the training focus lies.<br />

Technical Expertise<br />

Development against technical competency<br />

frameworks that set out the practical skills<br />

and knowledge required within your<br />

chosen discipline.<br />

Access to a core technical curriculum specific<br />

to your discipline.<br />

A professional or technical mentor to attain<br />

Chartership.<br />

Business Execution<br />

<strong>Global</strong> induction to <strong>GSK</strong> and GMS.<br />

Lean <strong>Manufacturing</strong> and Six Sigma training<br />

and accreditation.<br />

Business networking events.<br />

Site and role specific development e.g. Health<br />

& Safety, Quality Management Systems,<br />

Project Management.<br />

PROFESSIONAL ACCREDITATION (CHARTERSHIP)<br />

We encourage employees to attain membership<br />

of appropriate professional bodies and we provide<br />

practical support to assist them. Currently our<br />

internal training programmes are accredited by<br />

IChemE and IMechE to provide the mentored<br />

professional development required to prepare for<br />

chartered and incorporated status. And we are<br />

working towards similar accreditation for Chemists.<br />

High Performance Behaviours (HPBs)<br />

These are the building blocks of skilful performance<br />

and set the <strong>GSK</strong> standard for defining outstanding<br />

leadership in dynamic, competitive and complex<br />

business environments.<br />

At this early stage in your career, we will work<br />

with you to develop all your behaviours, whilst<br />

focusing in particular on: Information Search,<br />

Creating Business Solutions, Influencing,<br />

Communication, and Flexible Thinking.<br />

Self Awareness<br />

You will be given a senior development mentor.<br />

Leadership Edge – leadership style diversity<br />

to drive GMS culture.<br />

Personal Resilience.<br />

Energy for Performance.<br />

360-degree feedback – feedback from your<br />

colleagues, managers and stakeholders and<br />

yourself to aid your development.<br />

Career Planning & Networking.<br />

11


WHY COME AND WORK IN THE<br />

PHARMACEUTICAL SECTOR?<br />

Clearly, <strong>GSK</strong> and the pharmaceutical sector offer<br />

huge scope for scientists and engineers to work in<br />

the development and manufacture of drugs. Our<br />

multi-disciplinary teams see engineers working<br />

alongside chemists and pharmacists to research and<br />

develop the active pharmaceutical ingredient, and<br />

then formulate it into the product that a patient<br />

takes. Our products include classic pharmaceuticals<br />

(prescribed medicines), biopharmaceuticals (such<br />

as vaccines) and consumer products (over-thecounter<br />

medicines).<br />

Across the pharmaceutical industry there are<br />

some very large companies and most cover all<br />

areas of the industry. Some organisations, like<br />

biopharmaceuticals, are very specialist. So, too, are<br />

generic drug manufacturers – tending to have large<br />

manufacturing arms and small research departments.<br />

So while, for all engineers and scientists, there is<br />

the lure of more commercial roles – if you want<br />

to use your technical skills to assist in the rapid<br />

commercialisation of our products, you need not<br />

look further.<br />

12<br />

Is it right for me?<br />

If you can answer ‘yes’ to the following questions<br />

then <strong>GSK</strong> and the <strong>Global</strong> <strong>Manufacturing</strong> and<br />

Supply business may well be for you:<br />

A) Would you rather be making drugs that save<br />

lives, improve the quality of people’s lives and<br />

make a difference to society than stare at a<br />

screen looking for small movements in<br />

equity prices?<br />

B) Can you see yourself working in an industry<br />

making radical changes to the development<br />

and manufacture of our products or would<br />

you rather be reconciling balance sheets?<br />

C) Would developing all-new, state-of-the-art<br />

technology be a better reason for getting out<br />

of bed in the morning than heading off to<br />

sue someone?<br />

Compensation & Benefits –<br />

the TotalReward<br />

<strong>GSK</strong> offers you unique opportunities for career and<br />

personal development, flexible work options where<br />

appropriate, and excellent facilities, because we<br />

understand there’s more to job satisfaction than<br />

just your pay and benefits. But of course, the pay<br />

and benefits are important too.<br />

So, when you join <strong>GSK</strong>, you become part of a<br />

talented and highly motivated team of people who,<br />

together and individually, contribute to <strong>GSK</strong>’s<br />

global mission. And in return, you receive your<br />

TotalReward – the <strong>GSK</strong> pay and benefits package.<br />

In no particular order, this includes a competitive<br />

salary, a performance-based bonus, a pension plan<br />

with regular contributions from <strong>GSK</strong>, and<br />

opportunities to save for the future with help<br />

from <strong>GSK</strong>.<br />

You’ll also have regular salary reviews as part of the<br />

Technical Development Programme. This ensures<br />

that as you develop professionally, you are<br />

rewarded appropriately. And you have access to<br />

private healthcare, holidays, an employee advice<br />

service, and a variety of plans to help you save tax.<br />

(If you want more information on TotalReward visit<br />

www.gsk.com/uk-students and select the<br />

‘Working at <strong>GSK</strong>’ option.)<br />

At <strong>GSK</strong>, we believe there’s<br />

A CLEAR LINK between looking after our people<br />

and caring for our customers. We know our customers are in<br />

safe hands because WE INVEST IN OUR PEOPLE’S FUTURE.<br />

We make sure they are WELL DEVELOPED, are SUPPORTED<br />

both PROFESSIONALLY and PERSONALLY, have plenty of<br />

OPPORTUNITIES TO PROGRESS and that their REWARDS<br />

REFLECT THEIR CONTRIBUTION. And perhaps, even more<br />

importantly, we ensure that they’re able to do what they do<br />

best, as we’ve developed an environment that brings the<br />

BEST OUT OF PEOPLE FROM ALL BACKGROUNDS.<br />

We have developed an OPEN, TEAM-BASED CULTURE<br />

that ENCOURAGES IDEAS SHARING and<br />

spurs people on to FIND NEW WAYS<br />

around familiar problems. Why do<br />

we value our people and their<br />

contributions so highly?<br />

PUT SIMPLY, WE<br />

CAN’T HELP<br />

BUT CARE.<br />

IT’S OUR BUSINESS<br />

TO CARE.


GMS<br />

will give you the<br />

TOOLS AND THE BEST<br />

POSSIBLE START FOR YOU TO<br />

BUILD YOUR CAREER at <strong>GSK</strong>.<br />

You’ll get an EXCEPTIONAL<br />

TECHNICAL FOUNDATION, REGULAR<br />

DEVELOPMENT REVIEWS and a<br />

STRUCTURED PROGRAMME<br />

to follow. The spine of this is<br />

A SERIES OF PLACEMENTS<br />

that will see you gain<br />

A STRONG OVERVIEW OF<br />

OUR BUSINESS. Once<br />

you’ve a clear idea of<br />

where your heart lies, WE’LL WORK<br />

WITH YOU to determine whether<br />

broader business exposure or more<br />

in-depth technical experience is right.<br />

Then YOU’LL BE FREE TO TAKE<br />

THE PATH THAT SUITS YOU.<br />

Before long, you’ll discover<br />

that YOUR PLACE AT <strong>GSK</strong><br />

IS EXACTLY WHERE<br />

YOU WANT<br />

I T T O<br />

BE.<br />

WE’LL PUT YOU<br />

IN YOUR PLACE.<br />

THE PROGRAMME<br />

Our Technical Development Programme offers<br />

a wide range of opportunities for engineers and<br />

scientists. It’s a three-year programme involving<br />

three placements in at least two of our business<br />

areas, and at different sites. Placements are usually<br />

within the UK or the Republic of Ireland, but<br />

overseas opportunities do sometimes arise.<br />

The first placement is for 16 months, the second is<br />

for 12 months, and the final placement is for eight<br />

months. Near the end of each, you’ll work with the<br />

management team to identify the next business<br />

area appropriate for your skills development (and<br />

our business needs). At the end of the programme,<br />

if you have delivered to the desired standards, you<br />

will be placed, with support, within the<br />

organisation.<br />

GETTING IN<br />

We have a three-stage recruitment process that<br />

starts with an application form and hopefully ends<br />

at an Assessment Centre. If your application is<br />

successful, we’ll invite you to a telephone<br />

interview, which uses a mixture of technical and<br />

competency-based questions. Throughout the<br />

process, we will explore your ability to apply the<br />

technical knowledge you have gained through<br />

your studies, and ask you to give examples of<br />

situations where you have demonstrated the<br />

behaviours we value as a business.<br />

GETTING ON<br />

The programme is focused on developing the next<br />

generation of Technical Leaders and Technical<br />

Specialists. As a result, we have clear competency<br />

frameworks in place to support your development<br />

and to help you visualise your own progress.<br />

We will work with you to identify your career path<br />

and ensure a detailed individual development plan<br />

is put in place in partnership with your manager.<br />

GMS Technical Development Programme<br />

Overview<br />

8-month Business Breadth Placement<br />

experience of wider business or people<br />

leadership at your Home Site.<br />

16-month Technical Foundation Placement<br />

putting your university studies into practice.<br />

12-month Technical Breadth Placement<br />

continuing to develop your technical skills at a<br />

different site, supply division or business unit.<br />

8-month Technical Depth Placement<br />

putting experience into practice at your Home<br />

Site or at one of our International Sites.<br />

Development Reviews<br />

13


WHAT DO WE HAVE TO OFFER?<br />

Graduate Programmes<br />

As a SCIENTIST, you could join our programme<br />

as an Analytical Chemist, Organic Chemist<br />

or Microbiologist.<br />

As an ENGINEER, you could join our programme<br />

as a Chemical/Process Engineer, Mechanical<br />

Engineer, Process Control & Automation Engineer,<br />

or Electrical Engineer.<br />

NOT A SCIENTIST OR ENGINEER? Maybe<br />

Chemometrics, Statistics, or one of our other <strong>GSK</strong><br />

graduate programmes will provide you with the<br />

challenge you are looking for.<br />

Placements<br />

We offer a number of Industrial placements in GMS<br />

to give you the opportunity to develop the skills<br />

you have learnt to date at university in a practical<br />

environment, learn new skills, and gain an insight<br />

into a career with a pharmaceutical company.<br />

Depending on how you’ve performed during a<br />

placement, they provide a fast-track route to our<br />

graduate programmes. Further details of all our<br />

placements can be found online.<br />

Summer placements are less frequent due to the<br />

nature of our business. However, they are<br />

sometimes available and typically last eight to<br />

twelve weeks. As well as developing your technical<br />

skills, our summer placements will provide you with<br />

an insight into life and work in <strong>GSK</strong>. Further details<br />

of all our summer placements can be found online.<br />

All product names in italics are trademarks of GlaxoSmithKline, its<br />

subsidiaries or associated companies.<br />

14<br />

SO<br />

WHAT’S NEXT?<br />

We suggest you hop online,<br />

and POINT YOUR CURSOR IN<br />

THE GENERAL DIRECTION OF THE<br />

<strong>GSK</strong> WEBSITE www.gsk.com/uk-students<br />

There, you’ll be able to discover more<br />

about each and every one of our<br />

graduate opportunities, as well as how the<br />

programmes work in terms of ROTATING<br />

THROUGH ROLES AND SPECIALISING<br />

IN SPECIFIC AREAS. And even if you’re<br />

not quite ready to join <strong>GSK</strong> as a fully<br />

fl edged graduate just yet, don’t worry.<br />

We’ve A RANGE OF INDUSTRIAL<br />

PLACEMENTS AND SUMMER PLACEMENTS<br />

ON OFFER. In fact, whether you’ve an<br />

engineering or science degree (or<br />

are working your way towards<br />

one), we’re confi dent we can<br />

provide THE PERFECT<br />

HOME FOR YOUR<br />

EXPERTISE.<br />

LET US TELL YOU<br />

WHERE TO GO.<br />

www.gsk.com/uk-students


www.gsk.com/uk-students<br />

<strong>GSK</strong> is proud to promote an open culture, encouraging people to be themselves and giving their ideas a chance to flourish.<br />

<strong>GSK</strong> is an equal opportunity employer.

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