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Climate Change and Health: Framing the issue

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<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue


Contents<br />

Foreword ......................................................05<br />

Executive Summary ......................................06<br />

Introduction ..................................................08<br />

1. What does <strong>the</strong> science say about<br />

climate change? .......................................09<br />

2. What does <strong>the</strong> science say about <strong>the</strong><br />

impact of climate change on health?.........11<br />

3. Where will <strong>the</strong> impacts be most felt? .........22<br />

4. What are <strong>the</strong> societal <strong>and</strong> economic<br />

benefits of addressing climate change<br />

related health impacts? .............................29<br />

5. What are <strong>the</strong> impacts <strong>and</strong> implications<br />

for <strong>the</strong> pharmaceutical industry? ...............31<br />

Conclusion ...................................................35<br />

Acknowledgements ......................................36<br />

Appendix 1 ...................................................37<br />

End Notes ....................................................38


Foreword<br />

Andrew Witty<br />

Chief Executive Officer<br />

GlaxoSmithKline<br />

Scientific research suggests that climate change will<br />

exacerbate existing health <strong>issue</strong>s, most notably in <strong>the</strong><br />

developing world. At GSK, we are actively seeking new<br />

partnerships, <strong>and</strong> new ways of acting as a catalyst for<br />

change. We are already making huge strides in tackling<br />

some of <strong>the</strong> key diseases that are likely to be most impacted<br />

by climate change. Current knowledge has only begun to<br />

scratch <strong>the</strong> surface of what <strong>the</strong>se impacts could be.<br />

My ambition is to see GSK <strong>and</strong> <strong>the</strong> pharmaceutical industry<br />

come toge<strong>the</strong>r to make a progressive industry response<br />

to climate change <strong>and</strong> health. There is an opportunity for<br />

us to work closely with o<strong>the</strong>r key stakeholders, to initiate a<br />

dialogue around <strong>the</strong> actions we can collectively take, <strong>and</strong><br />

to stimulate innovation <strong>and</strong> research in <strong>the</strong> area. As good<br />

corporate citizens, we all need to ensure that <strong>the</strong> impact of<br />

climate change on health is better understood so that we can<br />

form an appropriate response.<br />

This paper, developed jointly with Accenture <strong>and</strong> <strong>the</strong> Smith<br />

School of Enterprise <strong>and</strong> <strong>the</strong> Environment at <strong>the</strong> University<br />

of Oxford, is just <strong>the</strong> starting point of what I hope will be<br />

an inspirational journey. Many of <strong>the</strong> things we need to do<br />

require transformational change that could take many years,<br />

but we absolutely must start this journey today. The potential<br />

of what we can achieve by working in partnership is huge.<br />

Sir David King<br />

Director, Smith School of<br />

Enterprise <strong>and</strong> <strong>the</strong> Environment<br />

University of Oxford<br />

<strong>Climate</strong> change is now considered in many quarters to<br />

be one of <strong>the</strong> greatest new threats to health in <strong>the</strong> 21st<br />

century. Available research suggests that <strong>the</strong> health impact of<br />

climate change will be wide ranging including more frequent<br />

extreme wea<strong>the</strong>r events, increase in epidemics, <strong>and</strong> food<br />

<strong>and</strong> water scarcity. Although <strong>the</strong>re are still important gaps<br />

in scientific knowledge, <strong>the</strong>re is little doubt that <strong>the</strong> greatest<br />

health impact of climate change will be borne by developing<br />

countries already struggling from poverty <strong>and</strong> a host of o<strong>the</strong>r<br />

socioeconomic <strong>and</strong> health problems.<br />

As responsible stakeholders, <strong>the</strong> healthcare industry has an<br />

important role to play in helping <strong>the</strong> global community better<br />

underst<strong>and</strong> <strong>the</strong> impact of climate change on healthcare <strong>and</strong><br />

what could be done to mitigate <strong>the</strong>se impacts. On <strong>the</strong> o<strong>the</strong>r<br />

h<strong>and</strong> <strong>the</strong> global community has a right to know <strong>the</strong> industry’s<br />

own contribution to climate change <strong>and</strong> <strong>the</strong> range of steps<br />

it is taking to reduce its carbon footprint. Recent history<br />

suggests that businesses that take <strong>the</strong> lead in responding<br />

to climate change will ultimately put <strong>the</strong>mselves ahead of<br />

<strong>the</strong> curve.<br />

The Smith School of Enterprise <strong>and</strong> <strong>the</strong> Environment is<br />

pleased to be collaborating with GlaxoSmithkline (GSK) <strong>and</strong><br />

Accenture on this project which seeks to highlight <strong>the</strong> impact<br />

of climate change on health.<br />

It is my hope that this report will instigate more research <strong>and</strong><br />

wider discussion on this extremely important topic.<br />

<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

Peter Lacy<br />

Managing Director<br />

Accenture Sustainability<br />

Services, EALA<br />

In my discussions with executives around <strong>the</strong> world, it is<br />

clear that climate change is now a concern across industries<br />

<strong>and</strong> markets. The <strong>Health</strong> sector sits at <strong>the</strong> interface where<br />

climate change impacts society <strong>and</strong> stakeholders in <strong>the</strong>ir<br />

daily lives. However, despite much good work by a number<br />

of academics <strong>and</strong> international organisations, significant gaps<br />

still exist in our underst<strong>and</strong>ing of <strong>the</strong>se health impacts.<br />

It is in this context that <strong>the</strong> authors of this paper have<br />

partnered to help frame <strong>the</strong> debate, with support from an<br />

inter-disciplinary team of experts. The research findings<br />

suggest that <strong>the</strong>re is opportunity for industry to better<br />

underst<strong>and</strong> <strong>the</strong> <strong>issue</strong>s <strong>and</strong> implications <strong>and</strong> develop an<br />

appropriate response. Through planning for <strong>the</strong> longer term<br />

– engaging stakeholders, building resilience, driving science<br />

<strong>and</strong> innovation – companies can integrate climate change<br />

<strong>and</strong> health into future strategies <strong>and</strong> be prepared to respond<br />

<strong>and</strong> adapt.<br />

There are economic rewards at stake; up to 2030 <strong>the</strong><br />

benefits of tackling <strong>the</strong> health impacts of climate change may<br />

be as much as 0.6 - 1.0 per cent of current gross domestic<br />

product (GDP) for sub-Saharan Africa <strong>and</strong> South-East Asia.<br />

This paper is very much a humble first step by <strong>the</strong> partners<br />

to engage a broader set of stakeholders to frame <strong>the</strong> <strong>issue</strong>s<br />

<strong>and</strong> explore solutions. But I believe that first step is an<br />

important one.<br />

Foreword<br />

05


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

Executive Summary<br />

The Earth’s climate is changing<br />

Average world temperatures have risen over <strong>the</strong> past<br />

fifty years <strong>and</strong> are predicted to rise between 1.1 <strong>and</strong><br />

6.4°C (2.0 <strong>and</strong> 11.5°F) during <strong>the</strong> 21st century. Prevailing<br />

scientific opinion is that <strong>the</strong> greater <strong>the</strong> increase in<br />

temperature, <strong>the</strong> more severe <strong>and</strong> variable <strong>the</strong> effects<br />

of climate change will be. Fur<strong>the</strong>r <strong>and</strong> more frequent<br />

warm spells, heatwaves, changes to <strong>the</strong> Earth’s humidity<br />

<strong>and</strong> rainfall patterns are anticipated. Meanwhile extreme<br />

wea<strong>the</strong>r events (EWEs) including drought, floods, hurricanes<br />

<strong>and</strong> acute high tides have become increasingly likely.<br />

<strong>Climate</strong> change will impact health<br />

<strong>Change</strong>s in temperature may bring some marginal<br />

improvements to health, such as <strong>the</strong> contraction of malarial<br />

zones in parts of Africa <strong>and</strong> fewer cold wea<strong>the</strong>r deaths in<br />

temperate regions such as <strong>the</strong> UK. However, <strong>the</strong> overall<br />

impact of climate change on health will be negative.<br />

In fact, climate change has been cited by some as<br />

<strong>the</strong> biggest global health threat of <strong>the</strong> 21st century,<br />

jeopardising <strong>the</strong> lives <strong>and</strong> wellbeing of billions of people. 1<br />

Extreme wea<strong>the</strong>r <strong>and</strong> heatwaves will have a direct impact<br />

on morbidity <strong>and</strong> mortality. Meanwhile an indirect effect<br />

of climate change on health will be <strong>the</strong> growing difficulty<br />

for many regions in accessing sufficient food, clean water<br />

<strong>and</strong> sanitation. Issues such as climate-induced migration<br />

will fur<strong>the</strong>r add to <strong>the</strong> health burden. 2<br />

The pharmaceutical industry has a role to play.<br />

Underst<strong>and</strong>ing <strong>the</strong> impact that climate change could<br />

have on human health is important for future disease<br />

06 Executive Summary<br />

control <strong>and</strong> health infrastructure planning. It will also help<br />

to ensure that industries <strong>and</strong> governments are prepared<br />

to effectively respond <strong>and</strong> adapt. GlaxoSmithKline (GSK)<br />

recognises that climate change may adversely impact<br />

health, <strong>and</strong> that <strong>the</strong> pharmaceutical industry should<br />

prepare to respond. GSK has partnered with Accenture<br />

<strong>and</strong> <strong>the</strong> Smith School of Enterprise <strong>and</strong> <strong>the</strong> Environment<br />

at <strong>the</strong> University of Oxford to examine <strong>the</strong> science on<br />

climate change <strong>and</strong> health, increase collaboration around<br />

<strong>the</strong> <strong>issue</strong> <strong>and</strong> underst<strong>and</strong>ing of it, as well as inform future<br />

business strategies. This involved a review of over 200<br />

academic articles <strong>and</strong> reports, as well as interviews with<br />

leading experts <strong>and</strong> academics in <strong>the</strong> field.<br />

Uncertainties<br />

To date, although growing, debate <strong>and</strong> dialogue on <strong>the</strong><br />

<strong>issue</strong> of climate change <strong>and</strong> health have been limited.<br />

The ability to underst<strong>and</strong> <strong>the</strong> <strong>issue</strong>s is clouded by<br />

uncertainty <strong>and</strong> significant knowledge gaps. Fur<strong>the</strong>rmore,<br />

it is difficult to isolate <strong>the</strong> impact of climate change on<br />

health from o<strong>the</strong>r influencing <strong>and</strong> interrelating socioeconomic<br />

factors that fur<strong>the</strong>r complicate <strong>the</strong> relationship.<br />

These challenges raise three questions:<br />

• What do we know about <strong>the</strong> impacts of climate change<br />

on health?<br />

• Where are <strong>the</strong> gaps in our current knowledge?<br />

• What are <strong>the</strong> implications for <strong>the</strong> pharmaceutical<br />

industry?<br />

What we know<br />

Although <strong>the</strong> current evidence base does not accurately<br />

predict <strong>the</strong> scale of <strong>the</strong> impacts, it does point to <strong>the</strong> fact<br />

that <strong>the</strong> effects of climate change on health are likely to<br />

increase. Rising temperatures, more extreme wea<strong>the</strong>r<br />

events <strong>and</strong> changes in air quality are highly likely to<br />

have a negative impact on six existing health concerns,<br />

particularly in developing countries:<br />

• <strong>Health</strong> effects related to EWEs<br />

• Cardio-respiratory diseases<br />

• Temperature-related health effects<br />

• Malnutrition<br />

• Vector-borne diseases<br />

• Waterborne diseases<br />

Eight infectious diseases have been identified as<br />

particularly sensitive to climate change. The epidemiology<br />

of malaria <strong>and</strong> cholera is particularly susceptible to<br />

changes in climate, with epidemics highly correlated to<br />

periods of increased rain <strong>and</strong> temperature.<br />

Many of <strong>the</strong> most serious public health consequences of<br />

climate change will be experienced by <strong>the</strong> world’s poorest<br />

nations, increasing global health inequities. 3 For example,<br />

malnutrition affects one in three people worldwide<br />

<strong>and</strong> is one of <strong>the</strong> most serious global health problems<br />

according to <strong>the</strong> World <strong>Health</strong> Organization (WHO). 4 This<br />

is set to worsen in <strong>the</strong> face of climate change. Changing<br />

temperature, precipitation, humidity, rainfall <strong>and</strong> EWEs


will exacerbate food insecurity in many regions, 5 <strong>and</strong> per<br />

capita calorie intake could drop by 5.7 per cent by 2050<br />

in developing countries. 6<br />

Meanwhile, neglected tropical diseases (NTDs) – <strong>the</strong><br />

most common infections in <strong>the</strong> 2.7 billion people living on<br />

less than $2 a day 7 – are likely to be <strong>the</strong> most sensitive<br />

to climate change.This would exacerbate <strong>the</strong> cycle of<br />

poverty, vulnerability <strong>and</strong> mortality in <strong>the</strong> developing<br />

world. South-East Asia <strong>and</strong> sub-Saharan Africa are <strong>the</strong><br />

regions of <strong>the</strong> world most susceptible to climate change<br />

<strong>and</strong> its health effects. According to <strong>the</strong> WHO, in 2000<br />

<strong>the</strong>se two regions accounted for over three-quarters of<br />

<strong>the</strong> estimated global disability-adjusted life years (DALYs)<br />

lost because of climate change 8 – a DALY represents<br />

one year of ‘healthy’ life.<br />

Tackling <strong>the</strong> impacts of climate change on malaria,<br />

malnutrition <strong>and</strong> diarrhoeal disease could result in<br />

significant economic benefits; up to 2030 this could be<br />

as much as 0.6 per cent to 1.0 per cent of current gross<br />

domestic product (GDP) for sub-Saharan Africa <strong>and</strong><br />

South-East Asia. Dealing with <strong>the</strong> impacts of climate<br />

change on specific diseases will deliver substantial<br />

economic benefits. For example, managing climate<br />

change related cases of malaria in Africa corresponds to<br />

a net economic benefit of approximately US$14 billion. 9<br />

What we don’t know<br />

Current knowledge has only begun to scratch <strong>the</strong> surface<br />

of what <strong>the</strong> impacts of climate change on health could<br />

be. Significant gaps still exist in our underst<strong>and</strong>ing of<br />

<strong>the</strong> timing, severity <strong>and</strong> geographical range of <strong>the</strong> health<br />

impacts of climate change. Limitations in <strong>the</strong> modelling<br />

of climate change <strong>and</strong> uncertainties in relation to <strong>the</strong> local<br />

<strong>and</strong> regional effects remain key gaps in our knowledge.<br />

There are also doubts regarding specific health <strong>and</strong><br />

disease impacts, a lack of long-term health data, <strong>and</strong><br />

difficulties in predicting how humans will mitigate<br />

<strong>and</strong> adapt.<br />

Finally, <strong>the</strong>re remains a need for continuing <strong>and</strong><br />

exp<strong>and</strong>ing existing research to better underst<strong>and</strong> <strong>the</strong><br />

relationship between climate <strong>and</strong> health, <strong>the</strong> influence of<br />

modulating factors <strong>and</strong> profiles of vulnerable individuals<br />

<strong>and</strong> populations.<br />

Implications<br />

The impact of climate change on health may alter <strong>the</strong><br />

pharmaceutical industry in <strong>the</strong> long term, but is less<br />

likely to dramatically alter business or operating models<br />

in <strong>the</strong> immediate future. Policy responses will have to be<br />

formulated under conditions of uncertainty. 10<br />

Companies within <strong>the</strong> industry will need to underst<strong>and</strong><br />

<strong>the</strong> <strong>issue</strong>s involved <strong>and</strong> be prepared to respond <strong>and</strong><br />

adapt to changing dem<strong>and</strong>s. Through planning for <strong>the</strong><br />

longer term – engaging stakeholders, building resilience,<br />

driving science <strong>and</strong> innovation – <strong>the</strong> industry can<br />

integrate climate change <strong>and</strong> health into future strategies.<br />

GSK, Accenture <strong>and</strong> <strong>the</strong> Smith School of Enterprise <strong>and</strong><br />

<strong>the</strong> Environment at <strong>the</strong> University of Oxford welcome<br />

partnership on this <strong>issue</strong>, particularly to examine <strong>the</strong><br />

existing knowledge gaps <strong>and</strong> to begin to answer some<br />

of <strong>the</strong> questions that remain. Most importantly, we invite<br />

stakeholders to work with us to use this as a starting<br />

point for action <strong>and</strong> collaboration.<br />

<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

We welcome<br />

partnership on this<br />

<strong>issue</strong>, particularly to<br />

examine <strong>the</strong> existing<br />

knowledge gaps <strong>and</strong><br />

to begin to answer<br />

some of <strong>the</strong> questions<br />

that remain.<br />

Executive Summary<br />

07


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

Introduction<br />

Awareness of <strong>the</strong> links between climate change <strong>and</strong><br />

public health has grown steadily over <strong>the</strong> last decade.<br />

Scientific reports indicate potential trends <strong>and</strong> healthrelated<br />

challenges that society may face as a result<br />

of <strong>the</strong> changing climate. However, <strong>the</strong>y also point to<br />

<strong>the</strong> complexity of <strong>the</strong> relationship between climate<br />

change <strong>and</strong> health, as well as to significant gaps <strong>and</strong><br />

uncertainties in current knowledge.<br />

GlaxoSmithKline (GSK), toge<strong>the</strong>r with Accenture <strong>and</strong> <strong>the</strong><br />

Smith School of Enterprise <strong>and</strong> <strong>the</strong> Environment at <strong>the</strong><br />

University of Oxford, aims to frame <strong>the</strong> discussion around<br />

climate change <strong>and</strong> health – what we know, what we don’t<br />

know <strong>and</strong> what <strong>the</strong> impacts <strong>and</strong> implications might be.<br />

Ra<strong>the</strong>r than provide all <strong>the</strong> answers, we aim to increase<br />

awareness of existing knowledge. We are committed to<br />

initiating a process of multi-stakeholder dialogue on this<br />

<strong>issue</strong> with, amongst o<strong>the</strong>rs, <strong>the</strong> pharmaceutical industry,<br />

healthcare professionals, governments <strong>and</strong> civil society.<br />

08 Introduction<br />

The following chapters aim to provide a perspective on<br />

<strong>the</strong> following five questions:<br />

• What does <strong>the</strong> science say about climate change?<br />

• What does <strong>the</strong> science say about <strong>the</strong> impact of climate<br />

change on health?<br />

• Where will <strong>the</strong> impacts be most felt?<br />

• What are <strong>the</strong> societal <strong>and</strong> economic benefits of<br />

addressing climate change related health impacts?<br />

• What are <strong>the</strong> impacts <strong>and</strong> implications for <strong>the</strong><br />

pharmaceutical industry?<br />

Background:<br />

Chapters 1 <strong>and</strong> 2 in this report<br />

are based on an academic paper<br />

developed by Oxford University’s<br />

Smith School of Enterprise <strong>and</strong> <strong>the</strong><br />

Environment, GSK <strong>and</strong> Accenture.<br />

This academic paper examined<br />

over 200 articles <strong>and</strong> papers<br />

to underst<strong>and</strong> <strong>the</strong> current literature<br />

<strong>and</strong> science on climate change <strong>and</strong><br />

health <strong>and</strong> was reviewed by<br />

a panel of leading academics from<br />

<strong>the</strong> Australian National University,<br />

Harvard University, Jawaharlal<br />

Nehru University, New Delhi, <strong>the</strong><br />

London School of Hygiene <strong>and</strong><br />

Tropical Medicine <strong>and</strong> University<br />

College London.<br />

This report was also informed<br />

by interviews, conducted<br />

by Accenture, with over 20<br />

leading experts from business,<br />

academia <strong>and</strong> non-governmental<br />

organisations (NGOs).


1. What does <strong>the</strong> science say<br />

about climate change?<br />

World temperatures have risen over <strong>the</strong> past fifty<br />

years. The rise in global average temperature is thought<br />

to be a direct result of <strong>the</strong> build-up of human-generated<br />

greenhouse gases (GHGs) – primarily carbon dioxide<br />

(CO 2 ). 11 Fur<strong>the</strong>r average global temperature rises are<br />

predicted to take place during <strong>the</strong> 21st century –<br />

between 1.1 <strong>and</strong> 6.4°C (2.0 <strong>and</strong> 11.5°F) depending<br />

on future GHG emissions <strong>and</strong> <strong>the</strong> Earth’s response<br />

to changing conditions 12 (see Figure 1.1). The<br />

Intergovernmental Panel on <strong>Climate</strong> <strong>Change</strong> (IPCC)<br />

is 90 per cent confident that as a result of rising<br />

temperatures, <strong>the</strong> world will see more frequent warm<br />

spells, heatwaves, humidity <strong>and</strong> heavy rainfall. This is<br />

anticipated to lead to an increase in extreme wea<strong>the</strong>r<br />

events (EWEs) including droughts, desertification, tropical<br />

cyclones, floods, hurricanes <strong>and</strong> extreme high tides.13<br />

Experts predict a variety of environmental health impacts<br />

as average global surface temperature rises (see Figure<br />

1.2). Ecosystem services (benefits to humans supplied<br />

by natural ecosystems) such as plant pollination, food<br />

Box 1.1: The Intergovernmental Panel on <strong>Climate</strong><br />

<strong>Change</strong> (IPCC)<br />

The IPCC is a scientific intergovernmental body that evaluates<br />

<strong>the</strong> risk of climate change <strong>and</strong> its potential environmental <strong>and</strong><br />

socio-economic consequences. The IPCC <strong>issue</strong>d comprehensive<br />

assessments in 1990, 1996, 2001 <strong>and</strong> most recently <strong>the</strong> Fourth<br />

Assessment Report (AR4), released in 2007. A Fifth Assessment is<br />

due for release in 2014.<br />

yields, oxygen production <strong>and</strong> <strong>the</strong> provision of clean<br />

water will be impacted, as well as biodiversity. Hundreds<br />

of millions of people in mid-latitudes <strong>and</strong> semi-arid<br />

low latitudes will become exposed to increased water<br />

<strong>and</strong> food stress as a consequence of <strong>the</strong> dramatic<br />

decrease in water availability <strong>and</strong> <strong>the</strong> resulting reduction<br />

in cereal productivity. Meanwhile, many coastal areas will<br />

experience increased damage from floods, storms <strong>and</strong><br />

rising sea levels.<br />

Scientists also suggest certain thresholds or ‘tipping<br />

points’ could be triggered during this century. This<br />

would put polar sea ice <strong>and</strong> ice sheets at risk, causing<br />

potential changes in wea<strong>the</strong>r systems such as Atlantic<br />

<strong>the</strong>rmohaline circulation, <strong>the</strong> El Niño sou<strong>the</strong>rn oscillation,<br />

<strong>and</strong> <strong>the</strong> Indian summer monsoon.<br />

Note: These scenarios are described in <strong>the</strong> IPCC Special Report on Emissions<br />

Scenarios (SRES, 2000). The SRES scenarios are grouped into four scenario<br />

families (A1, A2, B1 <strong>and</strong> B2) that explore alternative development pathways,<br />

covering a wide range of demographic, economic <strong>and</strong> technological driving<br />

forces <strong>and</strong> resulting GHG emissions.<br />

A1 assumes a world of very rapid economic growth, a global population<br />

that peaks in mid-century <strong>and</strong> rapid introduction of new <strong>and</strong> more efficient<br />

technologies. A1 is divided into three groups that describe alternative directions<br />

AR4 is <strong>the</strong> most comprehensive syn<strong>the</strong>sis of climate change<br />

science to date. Experts from more than 130 countries contributed<br />

to <strong>the</strong> assessment. More than 450 lead authors received input<br />

from around 800 contributing authors, <strong>and</strong> an additional 2,500<br />

experts reviewed draft documents.<br />

Despite events in 2010 <strong>the</strong> IPCC remains <strong>the</strong> most cited <strong>and</strong><br />

respected source of information on climate change. Basing its<br />

Global surface warming ( o C)<br />

6.0<br />

5.0<br />

4.0<br />

3.0<br />

2.0<br />

1.0<br />

0<br />

-1.0<br />

<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

Figure 1.1<br />

Global temperatures are anticipated<br />

to increase<br />

Scenarios for surface temperature projections<br />

Low (B1)<br />

Central (A1B)<br />

High (A2)<br />

Year 2000 constant<br />

concentrations<br />

20th century<br />

1900<br />

Source: IPCC (2007)<br />

2000<br />

Year<br />

2100<br />

of technological change: fossil intensive (A1FI), non-fossil energy resources (A1T)<br />

<strong>and</strong> a balance across all sources (A1B).<br />

B1 describes a convergent world, with <strong>the</strong> same global population as A1,<br />

but with more rapid changes in economic structures toward a service <strong>and</strong><br />

information economy.<br />

A2 describes a very heterogeneous world with high population growth, slow<br />

economic development <strong>and</strong> slow technological change.<br />

No likelihood has been attached to any of <strong>the</strong> SRES scenarios<br />

assessment mainly on peer reviewed <strong>and</strong> published scientific<br />

literature, <strong>the</strong> Panel is seen as an authoritative source; IPCC<br />

reports are widely cited in most debates related to climate change.<br />

From a health perspective, organisations that endorse <strong>the</strong> IPCC<br />

view include <strong>the</strong> American College of Preventative Medicine,<br />

<strong>the</strong> American Public <strong>Health</strong> Association, <strong>the</strong> Australian Medical<br />

Association, <strong>the</strong> World Federation of Public <strong>Health</strong> Associations,<br />

<strong>and</strong> <strong>the</strong> World <strong>Health</strong> Organization (WHO). 14<br />

What does <strong>the</strong> science say about climate change? 09


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong> <strong>Health</strong>: <strong>Framing</strong> Paper <strong>the</strong> Issue<br />

“ Warming of <strong>the</strong><br />

climate system is<br />

unequivocal, as is<br />

now evident from<br />

observations of<br />

increases in global<br />

average air <strong>and</strong><br />

ocean temperatures,<br />

widespread melting<br />

of snow <strong>and</strong> ice,<br />

<strong>and</strong> rising global<br />

average sea level.”<br />

(IPCC 2007)<br />

010Introduction<br />

10 What does <strong>the</strong> science say about climate change?<br />

Figure 1.2<br />

Experts predict a variety of environmental <strong>and</strong> health impacts<br />

as global average surface temperatures rise<br />

Selected impacts of global average annual temperature change relative to 1980–1999 (ºC)<br />

Food <strong>and</strong> Water<br />

Ecosystem<br />

Coast<br />

<strong>Health</strong><br />

Increase in<br />

Temperature<br />

* Significant is defined as more than 40%<br />

Source: Adapted from IPCC (2007)<br />

0 1 2 3 4 5 o C<br />

Increased water availability in moist tropics <strong>and</strong> high latitudes<br />

Decreasing water availability <strong>and</strong> increasing drought in mid-latitudes <strong>and</strong> semi-arid low latitudes<br />

Hundreds of millions of people exposed to increased water stress<br />

Increased damage from floods <strong>and</strong> storms<br />

Tendencies for cereal productivity<br />

to decrease in low latitudes<br />

Up to 30% of species at<br />

increasing risk of extinction<br />

Increased morbidity <strong>and</strong> mortality from heat waves, floods <strong>and</strong> droughts<br />

<strong>Change</strong>d distribution of some disease vectors<br />

Millions more people could experience<br />

coastal flooding each year<br />

Productivity of all cereals<br />

decreases in low latitudes<br />

About 40% of global<br />

coastal wetl<strong>and</strong>s lost<br />

Increasing burden from malnutrition, diarrhoeal, cardio-respiratory <strong>and</strong> infectious diseases<br />

Significant* extinction<br />

around <strong>the</strong> globe<br />

Substantial burden on health services<br />

0 1 2 3 4 5 o C


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

2. What does <strong>the</strong> science say about <strong>the</strong><br />

impact of climate change on health?<br />

The health of a population – if it is to be sustained –<br />

requires clean air, safe water, adequate food, tolerable<br />

temperatures, protection from <strong>the</strong> elements <strong>and</strong> high<br />

levels of biodiversity. <strong>Climate</strong> change is expected to alter<br />

<strong>the</strong>se conditions in various ways <strong>and</strong> to varying degrees<br />

throughout <strong>the</strong> world, with significant – <strong>and</strong> mostly<br />

adverse – health consequences. In both developed <strong>and</strong><br />

developing countries <strong>the</strong> overall tendency will be for<br />

existing health inequalities to be magnified by changing<br />

climates. This will result in <strong>the</strong> most vulnerable being<br />

disproportionately affected. 15<br />

Box 2.1: Overarching uncertainties<br />

• The extent to which <strong>the</strong> climate will change<br />

• What <strong>the</strong> local <strong>and</strong> regional impacts of climate change<br />

on health will be<br />

• What <strong>the</strong> interplay is between climate, health <strong>and</strong> o<strong>the</strong>r<br />

modulating factors<br />

• How humans will mitigate impacts <strong>and</strong>/or adapt<br />

Despite overarching uncertainties (see Box 2.1), we know<br />

that climate change is likely to have a negative impact on<br />

six existing health concerns:<br />

• <strong>Health</strong> effects related to EWEs<br />

• Cardio-respiratory diseases<br />

• Temperature-related health effects<br />

• Malnutrition<br />

• Vector-borne diseases<br />

• Waterborne diseases<br />

We know that<br />

climate change<br />

is likely to have a<br />

negative impact on<br />

six existing health<br />

concerns.<br />

What does <strong>the</strong> science say about <strong>the</strong> impact of climate change on health?<br />

11


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong> <strong>Health</strong>: <strong>Framing</strong> Paper <strong>the</strong> Issue<br />

Overview 2.1 <strong>Health</strong> effects related to extreme wea<strong>the</strong>r events (EWEs)<br />

Likely overall impact of climate change on health High negative<br />

IPCC level of confidence that changes will occur 80 per cent<br />

Timing of marginal impact Short term<br />

Headlines • EWEs are expected to continue increasing in<br />

frequency <strong>and</strong> severity. Developing countries are<br />

particularly vulnerable<br />

• EWEs increase mortality levels <strong>and</strong> exacerbate<br />

disease transmission. Uncertainties remain around<br />

<strong>the</strong> timing, frequency <strong>and</strong> magnitude of EWEs,<br />

particularly at a local level<br />

What we know<br />

The IPCC predicts an 80 per cent chance that <strong>the</strong>re will<br />

be an increase in mortality <strong>and</strong> morbidity due to climate<br />

change related EWEs. In 2007, 95 per cent of <strong>the</strong> 16,000<br />

global fatalities from EWEs could be directly attributed<br />

to climate change. 16 As climate has altered patterns of<br />

temperature, precipitation, winds <strong>and</strong> sea levels, EWEs<br />

have changed in frequency <strong>and</strong> intensity.<br />

The IPCC predicts that over most l<strong>and</strong> areas <strong>the</strong><br />

frequency of heatwaves, propensity of drought <strong>and</strong><br />

intensity of tropical cyclone activity is very likely to<br />

increase. At some level, <strong>the</strong> perceived increase in <strong>the</strong><br />

number of EWEs could be in part a consequence of<br />

improved data collection <strong>and</strong> reporting, however <strong>the</strong>re is<br />

a marked upward trend.<br />

Over <strong>the</strong> past 50 years, severe drought has increased<br />

by around one to three per cent around <strong>the</strong> globe. By<br />

2050 it is anticipated to increase to 12 per cent if global<br />

temperatures rise by 2°C above pre-industrial values. 17<br />

An increase in <strong>the</strong> frequency <strong>and</strong> intensity of hurricanes<br />

012Introduction<br />

12 What does <strong>the</strong> science say about <strong>the</strong> impact of climate change on health?<br />

has already been predicted for this century. 18 The number<br />

of people at risk from coastal flooding by storm surges<br />

is projected to increase from 75 million at <strong>the</strong> start of <strong>the</strong><br />

21st century to 200 million in <strong>the</strong> 2080s in a scenario of<br />

mid-range climate changes. 19<br />

EWEs not only result in increased mortality, <strong>the</strong>y also<br />

exacerbate disease transmission <strong>and</strong> place strain on<br />

healthcare systems. Inl<strong>and</strong> <strong>and</strong> coastal floods are<br />

already common; <strong>the</strong>y particularly impact South Asia <strong>and</strong><br />

Latin America, where poor drainage <strong>and</strong> storm water<br />

management increases <strong>the</strong> rate of infectious disease<br />

transmission. Extreme flooding in Brazil, for example, has<br />

been linked to an epidemic of rodent-borne leptospirosis<br />

as rodents sought refuge in houses when floods washed<br />

out <strong>the</strong>ir natural environment. 20 Meanwhile droughts<br />

increase communicable diseases: outbreaks of cholera<br />

are associated with <strong>the</strong> dry season in <strong>the</strong> Amazon when<br />

access to potable water is scarce. 21 Epidemic meningitis<br />

appears to be linked with <strong>the</strong> occurrence of droughts, as<br />

reflected by <strong>the</strong> recent spread of <strong>the</strong> disease into West<br />

Africa. 22 EWEs can also cause variation in <strong>the</strong> patterns of<br />

vector-borne diseases (diseases transmitted to humans<br />

by vectors such as mosquitoes) by creating or destroying<br />

favourable environments for vectors or by increasing<br />

human–vector contact.<br />

Secondary <strong>issue</strong>s <strong>and</strong> longer-term impacts include a loss<br />

of infrastructure <strong>and</strong> territory, <strong>and</strong> environmentally induced<br />

migration, as well as <strong>the</strong> potential to cause conflict over<br />

water, energy <strong>and</strong> o<strong>the</strong>r resources. 23 The Stern Review<br />

on <strong>the</strong> Economics of <strong>Climate</strong> <strong>Change</strong>, for example,<br />

suggests that drought <strong>and</strong> o<strong>the</strong>r climate-related shocks<br />

could cause conflict <strong>and</strong> violence. West Africa <strong>and</strong> <strong>the</strong><br />

Nile Basin are particularly vulnerable given <strong>the</strong>ir high<br />

water interdependence. 24 The spread of disease is also<br />

a common problem after EWEs. Survivors of EWEs<br />

often have an increased risk of contracting respiratory,<br />

diarrhoeal <strong>and</strong> waterborne diseases in <strong>the</strong> aftermath of an<br />

extreme event. This is due to population overcrowding,<br />

limited or no access to potable water <strong>and</strong> food, <strong>and</strong><br />

exposure to chemicals, pathogens <strong>and</strong> waste. 25 There<br />

is also evidence of increased mental stress post-EWE.<br />

One long-term study found that 15–20 per cent of people<br />

affected by a natural disaster reported symptoms of<br />

post-traumatic stress disorder. 26<br />

What we don’t know<br />

• The extent of <strong>the</strong> localised <strong>and</strong> specific<br />

relationships between temperature extremes,<br />

EWEs <strong>and</strong> health outcomes<br />

• The timing, frequency, geographical scope <strong>and</strong><br />

severity of future events<br />

• How to implement effective climate modelling <strong>and</strong><br />

warning systems<br />

*


Overview 2.2 Cardio-respiratory diseases<br />

Likely overall impact of climate change on health High negative<br />

IPCC level of confidence that changes will occur 80 per cent<br />

Timing of marginal impact Short term<br />

Headlines • <strong>Climate</strong> change will impact air quality <strong>and</strong> increase<br />

ground-level ozone, particularly in urban areas,<br />

leading to an increase in cardiorespiratory disease<br />

<strong>and</strong> cancer<br />

• Young children, <strong>the</strong> elderly <strong>and</strong> those with preexisting<br />

health conditions are especially vulnerable<br />

• Uncertainties remain around <strong>the</strong> exact link between<br />

climate change <strong>and</strong> individual cardio-respiratory<br />

What we know<br />

<strong>Climate</strong> change will impact air quality, especially in cities,<br />

potentially exacerbating <strong>the</strong> urban heat-isl<strong>and</strong> effect 27 <strong>and</strong><br />

increasing <strong>the</strong> prevalence of ground-level ozone (smog).<br />

Poor air quality is known to cause respiratory health<br />

problems. The IPCC is highly confident (80 per cent<br />

confidence) that <strong>the</strong>re will be an increase in cardiorespiratory<br />

morbidity <strong>and</strong> mortality associated with<br />

ground-level ozone.<br />

Ground-level ozone can damage lung t<strong>issue</strong>, <strong>and</strong> is<br />

especially harmful for those with asthma <strong>and</strong> o<strong>the</strong>r<br />

chronic lung diseases. Sunlight <strong>and</strong> high temperatures,<br />

combined with o<strong>the</strong>r pollutants such as nitrogen oxide<br />

<strong>and</strong> volatile organic compounds, can cause ground-level<br />

ozone to increase. The World <strong>Health</strong> Organization (WHO)<br />

estimated that poor air quality caused by climate change<br />

was responsible for over 2.4 million premature deaths in<br />

2000 alone – one third by outdoor air <strong>and</strong> ano<strong>the</strong>r third<br />

by indoor air – <strong>and</strong> accounts for approximately two per<br />

cent of <strong>the</strong> global cardiopulmonary disease burden. 28<br />

Particulate matter, nitrogen oxides <strong>and</strong> sulphur oxides<br />

can also have a negative impact on health. These<br />

effects, which are associated more with air pollution<br />

but potentially exacerbated by climate change, include<br />

aggravation of chronic respiratory <strong>and</strong> cardiovascular<br />

diseases, reduced work capacity, <strong>and</strong> effects on<br />

pulmonary function. 29<br />

Although climate change may increase <strong>the</strong> concentration<br />

of ground-level ozone, <strong>the</strong> magnitude of <strong>the</strong> effect<br />

remains uncertain. The effects of climate change <strong>and</strong><br />

wea<strong>the</strong>r on <strong>the</strong> behaviours of o<strong>the</strong>r pollutants are less<br />

well studied, <strong>and</strong> results vary by region. 30<br />

The populations most at risk of increased respiratory<br />

disease include children, pregnant women, people of low<br />

socio-economic status <strong>and</strong> those in congested urban<br />

areas. People living near to forests prone to fire are also<br />

<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

at high risk; a combination of human actions <strong>and</strong> climate<br />

change is likely to increase <strong>the</strong> extent <strong>and</strong> intensity of<br />

forest fires, leading to severe air pollution. 31<br />

<strong>Climate</strong> change can also expose patients with existing<br />

conditions (such as <strong>the</strong> elderly <strong>and</strong> overweight) to<br />

dangerous temperature extremes, placing additional<br />

stress on <strong>the</strong>ir cardiovascular systems. In Italy <strong>the</strong> summer<br />

of 2003 saw those aged over 65 years experience<br />

a 34 per cent greater risk of dying during hot days, with<br />

a significantly higher risk of respiratory disease. 32<br />

<strong>Climate</strong> change could also cause more allergy symptoms<br />

due to increases in atmospheric carbon dioxide<br />

concentration <strong>and</strong> temperature. A warmer climate is<br />

expected to promote <strong>the</strong> growth of moulds, weeds,<br />

grasses, <strong>and</strong> trees that cause allergic reactions in some<br />

people. For example, climate change has already caused<br />

<strong>the</strong> spring pollen season to begin earlier in North America. 33<br />

What we don’t know<br />

• The magnitude of <strong>the</strong> effect of climate change on<br />

pollen concentrations, particulates, ground-level<br />

ozone <strong>and</strong> o<strong>the</strong>r pollutants <strong>and</strong> <strong>the</strong> best means of<br />

adaptation<br />

• The effects of climate change on individual<br />

cardio-respiratory diseases<br />

• The isolated effects of climate change on<br />

cardio-respiratory diseases in comparison with<br />

o<strong>the</strong>r variables such as moving to lower-carbon<br />

living <strong>and</strong> o<strong>the</strong>r lifestyle choices<br />

What does <strong>the</strong> science say about <strong>the</strong> impact of climate change on health?<br />

*<br />

13


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong> <strong>Health</strong>: <strong>Framing</strong> Paper <strong>the</strong> Issue<br />

Overview 2.3 Temperature-related health effects<br />

Likely overall impact of climate change on health Moderate negative<br />

IPCC level of confidence that changes will occur 50-80 per cent<br />

Timing of marginal impact Short/Medium term<br />

Headlines • Although climate change will bring some benefits<br />

– including fewer deaths from cold wea<strong>the</strong>r – <strong>the</strong><br />

overall burden of rising temperatures will be negative<br />

• The negative effects will particularly be felt in<br />

developing countries where heat-related mortality<br />

<strong>and</strong> <strong>the</strong> potential secondary impact on subsistence<br />

<strong>and</strong> agriculture could be high<br />

• Uncertainties remain around our underst<strong>and</strong>ing of<br />

<strong>the</strong> impact in current high-temperature regions <strong>and</strong><br />

<strong>the</strong> link between climate change, ozone depletion<br />

<strong>and</strong> skin cancer<br />

What we know<br />

Increases in average temperature will bring a small<br />

improvement in health, particularly in temperate regions.<br />

In Britain, for example, warmer winters might reduce cold<br />

wea<strong>the</strong>r related mortalities. Estimates suggest that 9,000<br />

deaths per year could be avoided by 2025 in Engl<strong>and</strong><br />

<strong>and</strong> Wales with a 2.5°C increase in average winter<br />

temperature. 34 Overall, however, <strong>the</strong> impact of changing<br />

temperatures is likely to be negative. The IPCC is 50 per<br />

cent certain that climate change has increased heatwaverelated<br />

deaths, <strong>and</strong> expresses an 80 per cent level of<br />

certainty that increasing temperatures will have a negative<br />

impact on health. For each 1°C rise in temperature above<br />

a specified ceiling (which varies by region) death rates<br />

are predicted to rise by between one per cent <strong>and</strong> four<br />

per cent. 35 Hunger, malaria, flooding <strong>and</strong> water shortages<br />

014Introduction<br />

14 What does <strong>the</strong> science say about <strong>the</strong> impact of climate change on health?<br />

will threaten millions if global average temperatures<br />

rise by 2°C. 36<br />

The propensity for developed countries to experience<br />

heatwaves is increasing, with consequent impacts<br />

on levels of morbidity <strong>and</strong> mortality. Those with heart<br />

problems, asthma, <strong>the</strong> elderly <strong>and</strong> <strong>the</strong> young, <strong>and</strong> those<br />

without proper protection from excess heat (such as<br />

<strong>the</strong> homeless) can be especially vulnerable. In 2003,<br />

European temperatures rose 10–12°C higher than<br />

average during a heatwave, causing between 22,000 <strong>and</strong><br />

35,000 deaths. 37 In Chicago, a heatwave in July caused<br />

at least 700 additional deaths. Analysis of American<br />

<strong>and</strong> European heatwave data suggests that by 2009<br />

heatwaves in <strong>the</strong>se regions will be 25 per cent <strong>and</strong> 31<br />

per cent more frequent respectively. 38<br />

Although average temperatures are predicted to increase<br />

more dramatically in <strong>the</strong> nor<strong>the</strong>rn hemisphere, <strong>the</strong><br />

changes in developing regions may be more significant.<br />

This is due to <strong>the</strong> reliance of <strong>the</strong>se areas on small-scale<br />

farming, a fragile infrastructure <strong>and</strong> limited capacity to<br />

respond to emergencies. Many African communities<br />

will be at risk, particularly subsistence farmers with low<br />

incomes in sub-Saharan Africa. Increased temperatures<br />

leading to droughts may be exacerbating poverty levels<br />

<strong>and</strong> increasing vulnerability for small-scale farmers. United<br />

Nations (UN) scientists warned in 2005 that one in six<br />

countries are facing food shortages because of severe<br />

droughts that could become semi permanent. 39<br />

National communications report that climate change will<br />

cause a general decline in many subsistence crops, for<br />

example sorghum in Sudan, Ethiopia, Eritrea <strong>and</strong> Zambia;<br />

maize in Ghana; millet in Sudan; <strong>and</strong> groundnuts in<br />

Gambia. 40 Africa already accounts for a large proportion<br />

of <strong>the</strong> total additional people at risk of hunger as a result<br />

of climate change; by <strong>the</strong> 2080s it may account for<br />

<strong>the</strong> majority. 41<br />

What we don’t know<br />

• What <strong>the</strong> precise impact of heatwaves will be in<br />

current high temperature regions such as Asia,<br />

Africa <strong>and</strong> <strong>the</strong> Middle East<br />

• The frequency <strong>and</strong> intensity of heatwaves across<br />

various timescales<br />

*


Overview 2.4 Malnutrition<br />

Likely overall impact of climate change on health High negative<br />

IPCC level of confidence that changes will occur 80 per cent<br />

Timing of marginal impact Short/Medium term<br />

Headlines • Malnutrition will be one of <strong>the</strong> biggest health impacts<br />

associated with climate change<br />

• Food security will be threatened by changing<br />

temperature, precipitation humidity, rainfall <strong>and</strong><br />

EWEs – leading to an increase in malnutrition.<br />

• The developing world will be worst affected,<br />

particularly sub-Saharan Africa<br />

• Uncertainties remain around how disease patterns<br />

will change in <strong>the</strong> context of climate change induced<br />

malnutrition<br />

What we know<br />

The Food <strong>and</strong> Agricultural Organization (FAO) <strong>and</strong> World<br />

<strong>Health</strong> Organization (WHO) maintain that malnutrition is<br />

<strong>the</strong> most serious health problem worldwide. Currently<br />

malnutrition accounts for an estimated 15 per cent of<br />

disease in DALYs. 42<br />

About 178 million children globally are stunted <strong>and</strong><br />

1.5 million die annually from wasting, both important<br />

indicators of malnutrition. 43 <strong>Climate</strong> change could<br />

exacerbate this situation. The IPCC predicts an 80 per<br />

cent chance that climate change will increase malnutrition<br />

<strong>and</strong> consequent disorders, including those related to<br />

child growth <strong>and</strong> development.<br />

Changing temperature, precipitation, humidity, rainfall<br />

<strong>and</strong> EWEs will make food security more complex. 44<br />

In <strong>the</strong> short term <strong>the</strong> amount of farml<strong>and</strong> suitable for<br />

cereal crops could increase in North America (40 per<br />

cent), Nor<strong>the</strong>rn Europe (16 per cent), <strong>the</strong> Russian<br />

Federation (64 per cent), <strong>and</strong> East Asia (10 per cent),<br />

as a result of better growing conditions under warming. 45<br />

But in <strong>the</strong> long term, daily per capita calorie availability<br />

will drop between 2.3 per cent <strong>and</strong> 2.5 per cent by<br />

2050 in developed countries <strong>and</strong> up to 5.7 per cent in<br />

developing countries. 46 In 2009, most of <strong>the</strong> 960 million<br />

undernourished people lived in developing countries. 47<br />

<strong>Climate</strong> change is likely to increase food insecurity<br />

amongst many of <strong>the</strong>se populations. <strong>Climate</strong> change<br />

will also compound existing food insecurity. According<br />

to <strong>the</strong> UN World Food Programme, <strong>the</strong> number of food<br />

emergencies every year has increased from an average<br />

of 15 during <strong>the</strong> 1980s to more than 30. 48 For example,<br />

studies in countries such as Mali <strong>and</strong> Nepal suggest that<br />

by 2050, 72 per cent of <strong>the</strong> population could face serious<br />

food shortages. 49<br />

<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

According to <strong>the</strong> UN<br />

World Food Programme,<br />

<strong>the</strong> number of food<br />

emergencies every year<br />

has increased from an<br />

average of 15 during <strong>the</strong><br />

1980s to more than 30.<br />

What we don’t know<br />

• How disease patterns will change in <strong>the</strong> context of<br />

climate change induced malnutrition<br />

• The local effects of climate change on food yields,<br />

nutritional quality <strong>and</strong> price<br />

• How best to improve food security as wea<strong>the</strong>r<br />

patterns change<br />

What does <strong>the</strong> science say about <strong>the</strong> impact of climate change on health?<br />

*<br />

15


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong> <strong>Health</strong>: <strong>Framing</strong> Paper <strong>the</strong> Issue<br />

Overview 2.5 Vector-borne diseases<br />

Likely overall impact of climate change on health High negative<br />

IPCC level of confidence that changes will occur 80 per cent<br />

Timing of marginal impact Long term<br />

Headlines • <strong>Climate</strong> change will exacerbate current vector-borne<br />

disease through increased infection rate, increased<br />

geographical coverage <strong>and</strong> increased rate of<br />

breeding<br />

• The increase in temperature will in general exp<strong>and</strong><br />

malaria transmission zones, but could also lead to a<br />

contraction of malarial zones in some parts of Africa<br />

• Neglected tropical diseases are endemic in Africa,<br />

Asia <strong>and</strong> <strong>the</strong> Americas – but relatively little is known<br />

about <strong>the</strong> impact climate change will have on <strong>the</strong>ir<br />

prevalence<br />

What we know<br />

A vector is an insect or any living carrier that transmits<br />

an infectious disease (for example mosquitoes or ticks).<br />

Changing temperatures, rainfall patterns <strong>and</strong> EWEs are<br />

likely to influence <strong>the</strong> reproductive cycles <strong>and</strong> behaviours<br />

of <strong>the</strong>se vectors, leading to a more suitable environment<br />

for <strong>the</strong> spread of disease <strong>and</strong> <strong>the</strong> potential for <strong>the</strong><br />

emergence of new ones. As temperature increases, <strong>the</strong><br />

extrinsic incubation period (i.e. <strong>the</strong> period from when a<br />

vector acquires an infectious agent <strong>and</strong> is able to transmit<br />

<strong>the</strong> agent) becomes less. This in turn increases <strong>the</strong><br />

infection rate of <strong>the</strong> parasites, elevating <strong>the</strong> transmission<br />

levels of <strong>the</strong> disease.<br />

016Introduction<br />

16 What does <strong>the</strong> science say about <strong>the</strong> impact of climate change on health?<br />

The IPCC gives an 80 per cent level of certainty that<br />

climate change will affect vector-borne diseases. The<br />

extent of <strong>the</strong> impact of climate change will depend on<br />

<strong>the</strong> region, <strong>the</strong> carrier (water or vector) <strong>and</strong> <strong>the</strong> disease<br />

itself, as well as mitigation <strong>and</strong> prevention strategies.<br />

Many of <strong>the</strong> diseases that are highly sensitive to climate<br />

change <strong>and</strong> also have a significant global impact in<br />

terms of <strong>the</strong> loss of DALYs are vector-borne diseases.<br />

Examples include malaria, dengue, leishmaniasis <strong>and</strong><br />

schistosomiasis (see Figure 2.5).<br />

The impact of changes in temperature <strong>and</strong> climate could<br />

vary depending on <strong>the</strong> type of vector <strong>and</strong> parasite. In <strong>the</strong><br />

case of malaria for example, <strong>the</strong> minimum temperature<br />

required for development of <strong>the</strong> Plasmodium vivax<br />

parasite ranges from 14.5–16.5°C. For Plasmodium<br />

falciparum - <strong>the</strong> most deadly cause of malaria - it<br />

ranges from 16.5–19°C. The optimum conditions<br />

for development of <strong>the</strong> malaria parasite, however, are<br />

20–30°C temperature <strong>and</strong> 60 per cent relative humidity. 50<br />

However, <strong>the</strong> effect on specific parasites remains an area<br />

that requires fur<strong>the</strong>r research <strong>and</strong> underst<strong>and</strong>ing.<br />

The impact of climate change on malaria will also vary<br />

according to geography. In some places <strong>the</strong> geographical<br />

range will contract, elsewhere <strong>the</strong> geographical range will<br />

exp<strong>and</strong> <strong>and</strong> <strong>the</strong> transmission season may be changed<br />

(see Figure 2.3). Senegal, for example, has seen a 60<br />

per cent drop in malaria over <strong>the</strong> last 30 years owing to<br />

reduced precipitation. 51 However, with rising temperatures,<br />

traditionally cool climates <strong>and</strong> higher latitudes will become<br />

more suitable reproductive habitats; already warm zones<br />

may also see an increase in mosquito populations. Malaria<br />

has returned to central <strong>and</strong> nor<strong>the</strong>rn South America,<br />

much of Asia, some Mediterranean countries <strong>and</strong> much<br />

of <strong>the</strong> former USSR. Analysis of malaria morbidity data


Figure 2.3: <strong>Climate</strong> <strong>Change</strong> <strong>and</strong> Malaria<br />

<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

Cartographer/Designer:<br />

Hugo Ahlenius,<br />

UNEP/GRID-Arendal<br />

What does <strong>the</strong> science say about <strong>the</strong> impact of climate change on health?<br />

17


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong> <strong>Health</strong>: <strong>Framing</strong> Paper <strong>the</strong> Issue<br />

The IPCC gives an 80% level of<br />

certainty that climate change will affect<br />

vector-borne diseases.<br />

in Ethiopia indicates that higher minimum temperatures<br />

correlate with increased instances of malaria outbreaks. 52<br />

By 2080, 260–320 million more people are likely to be<br />

affected by malaria as more areas become infested<br />

with mosquitoes. 53 Scientific models also infer that <strong>the</strong><br />

geographical limits of dengue fever transmission are<br />

strongly determined by climate. On <strong>the</strong> assumption that<br />

o<strong>the</strong>r factors affecting dengue fever transmission remain<br />

<strong>the</strong> same, <strong>the</strong> global population at risk of dengue fever is<br />

anticipated to rise by 2 billion people by <strong>the</strong> 2080s. 54<br />

O<strong>the</strong>r neglected tropical diseases (NTDs) such as<br />

schistosomiasis, lymphatic filariasis, <strong>and</strong> onchocerciasis<br />

are endemic in <strong>the</strong> tropics, primarily in <strong>the</strong> developing<br />

regions of Africa, Asia <strong>and</strong> <strong>the</strong> Americas. NTDs are <strong>the</strong><br />

most common infections in <strong>the</strong> 2.7 billion people living on<br />

less than $2 a day 55 <strong>and</strong> <strong>the</strong>se diseases are likely to be<br />

<strong>the</strong> most sensitive to climate change, exacerbating<br />

<strong>the</strong> cycle of poverty, vulnerability <strong>and</strong> mortality in <strong>the</strong><br />

developing world. 56<br />

Owing to lack of attention, little is currently known about<br />

<strong>the</strong> pattern of <strong>the</strong> spread of <strong>the</strong>se diseases <strong>and</strong> <strong>the</strong>ir<br />

potential links to climate change. However, because<br />

insects tend to breed faster at higher temperatures, it<br />

018Introduction<br />

18 What does <strong>the</strong> science say about <strong>the</strong> impact of climate change on health?<br />

is very likely that <strong>the</strong> prevalence of <strong>the</strong>se diseases will<br />

increase with climate change. A recent study of <strong>the</strong><br />

schistosomiasis virus in China, for example, concluded<br />

that temperature increases have altered disease<br />

transmission <strong>and</strong> extended <strong>the</strong> disease northwards into<br />

currently non-endemic areas. 57 The study suggests that<br />

by 2050 <strong>the</strong> disease could cover 8.1 per cent of <strong>the</strong><br />

surface area of China. 58 Increasingly severe floods are also<br />

exacerbating <strong>the</strong> disease; flooding in <strong>the</strong> Yangtze River<br />

has been found to produce a nearly threefold increase<br />

in acute cases of schistosomiasis per annum compared<br />

with years of normal water levels. 59<br />

What we don’t know<br />

*<br />

• The effect of climate on <strong>the</strong> full spectrum of vectorborne<br />

diseases; <strong>and</strong> <strong>the</strong> full impact of temperature<br />

on rate of infection, geographic coverage <strong>and</strong> rate<br />

of breeding for specific parasites<br />

• Sufficient results from monitoring <strong>and</strong> surveillance<br />

of disease <strong>and</strong> mortality in sensitive regions<br />

(particularly in <strong>the</strong> developing world)<br />

• The link between climate change <strong>and</strong> neglected<br />

tropical diseases in detail<br />

Guide to Overviews 2.1 to 2.6<br />

• Likely impact of climate change on health <strong>and</strong> timing of marginal<br />

impact assessments for <strong>the</strong> six health concerns are based on<br />

qualitative assessments of <strong>the</strong> current evidence base <strong>and</strong> data<br />

• IPCC defines short, medium <strong>and</strong> long term as:<br />

short – 2010–2020; medium – 2020–2030; long – 2030 onwards 60


Overview 2.6 Waterborne diseases<br />

Likely overall impact of climate change on health Moderate negative<br />

IPCC level of confidence that changes will occur 50 per cent (for diarrhoeal disease)<br />

Timing of marginal impact Short/Medium term<br />

Headlines • Waterborne diseases are likely to increase because<br />

water sources will be put at risk as a result of EWEs<br />

• Diarrhoea, cholera <strong>and</strong> dengue are predicted to<br />

increase in developing regions<br />

• Uncertainties remain because of knowledge gaps<br />

on existing levels of prevalence, <strong>the</strong> impacts of<br />

better water management <strong>and</strong> adaptation on<br />

water security<br />

What we know<br />

Water is critical to human survival <strong>and</strong> good health.<br />

<strong>Change</strong>s in climate will have a direct impact on water<br />

temperature <strong>and</strong> precipitation frequency <strong>and</strong> intensity,<br />

<strong>the</strong>reby altering <strong>the</strong> earth’s water cycle (<strong>the</strong> movement<br />

of water above <strong>and</strong> below <strong>the</strong> Earth’s surface). As a<br />

result, <strong>the</strong> frequency of heavy rainfall, storms, floods<br />

<strong>and</strong> droughts will increase which, as well as having<br />

an immediate effect on mortality, will also affect water<br />

availability, quality <strong>and</strong> access. Waterborne diseases<br />

are particularly likely to increase with temperature <strong>and</strong><br />

frequency of EWEs, as drinking water from natural<br />

<strong>and</strong> infrastructural water sources will be put at risk,<br />

increasing exposure to unsafe water, <strong>the</strong> contamination<br />

of wells <strong>and</strong> boreholes, <strong>and</strong> a breakdown of infrastructure<br />

for dealing with sewage.<br />

The IPCC predicts, with a level of 50 per cent certainty,<br />

that climate change will, for example, increase <strong>the</strong><br />

burden of diarrhoeal diseases.<br />

Almost two million young children die annually because<br />

of poor sanitation or <strong>the</strong> use of unsafe water. 61 Diarrhoea<br />

alone accounts for about 40 per cent of all deaths of<br />

children under five <strong>and</strong> 80 per cent of those under two. 62<br />

Infection spreads through contaminated food or<br />

drinking water.<br />

Those with access to clean water usually recover<br />

from diarrhoea within a few days, but in malnourished<br />

populations it can lead to severe dehydration <strong>and</strong> death. 63<br />

In 2000, diarrhoea linked to climate change caused<br />

47,000 deaths, most in South-East Asia. Estimates for<br />

<strong>the</strong> future of diarrhoea-induced mortality in Africa<br />

predict over 60,000 deaths in 2030. 64 This is a 10 per<br />

cent increase in risk over what it would be without<br />

climate change. 65 Diarrhoeal diseases – along with<br />

<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

o<strong>the</strong>r waterborne diseases such as cholera – are climate<br />

sensitive (see Figure 2.3). Regional epidemics of cholera,<br />

for example, occur seasonally <strong>and</strong> are associated with<br />

periods of excessive rainfall, warm temperatures <strong>and</strong><br />

subsequent increases in aquatic plankton populations.<br />

O<strong>the</strong>r factors that impact waterborne diseases include<br />

localised management of watershed <strong>and</strong> catchments,<br />

changes in rainfall, sanitation, water availability <strong>and</strong><br />

access to medicine (see Box 2.2).<br />

What we don’t know<br />

• Information on prevalence, distribution <strong>and</strong> disease<br />

burden of individual diseases<br />

• Marginal impact assessment of climate change<br />

– <strong>and</strong> <strong>the</strong> effect of improved water <strong>and</strong> sanitation<br />

infrastructure <strong>and</strong> adaptation<br />

• The extent to which social, demographic <strong>and</strong><br />

political conditions will exacerbate water scarcity<br />

• The implications of different forms of local water<br />

catchment management on health<br />

What does <strong>the</strong> science say about <strong>the</strong> impact of climate change on health?<br />

*<br />

19


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong> <strong>Health</strong>: <strong>Framing</strong> Paper <strong>the</strong> Issue<br />

Figure 2.4: Tropical Diseases<br />

Disease<br />

Cholera<br />

Dengue<br />

Diarrhoeal diseases<br />

Influenza<br />

Leishmaniasis<br />

Malaria<br />

Meningococcal Meningitis<br />

Schistosomiasis<br />

Adapted from WHO factsheets 2011 http://www.who.int/topics/en/<br />

020Introduction<br />

20 What does <strong>the</strong> science say about <strong>the</strong> impact of climate change on health?<br />

An intestinal infection caused by a bacteria, <strong>and</strong> is often linked to contaminated supplies of drinking water. It causes<br />

severe diarrhoea <strong>and</strong> vomiting that can quickly lead to severe dehydration <strong>and</strong> death if treatment is not promptly given.<br />

A virus transmitted by mosquito. It occurs in tropical <strong>and</strong> sub-tropical areas of <strong>the</strong> world. Dengue fever symptoms range<br />

from a mild fever, to incapacitating high fever, with severe headache, pain behind <strong>the</strong> eyes, muscle <strong>and</strong> joint pain, <strong>and</strong> rash.<br />

Diarrhoea is usually a symptom of an infection in <strong>the</strong> intestinal tract, which can be caused by a variety of bacterial, viral<br />

<strong>and</strong> parasitic organisms. Infection is spread through contaminated food or drinking-water, or from person-to-person as a<br />

result of poor hygiene.<br />

A viral infection that affects mainly <strong>the</strong> nose, throat, bronchi <strong>and</strong>, occasionally, lungs. Infection is characterized by sudden<br />

onset of high fever, aching muscles, headache <strong>and</strong> severe malaise, non-productive cough <strong>and</strong> sore throat. The virus is<br />

transmitted easily from person to person via droplets <strong>and</strong> small particles produced when infected people cough or sneeze.<br />

Influenza tends to spread rapidly in seasonal epidemics.<br />

Caused by <strong>the</strong> Leishmania parasite which can be transmitted to humans when a s<strong>and</strong>fly infected with <strong>the</strong> parasite bites<br />

<strong>the</strong>m. The most severe form of <strong>the</strong> disease attacks <strong>the</strong> internal organs <strong>and</strong> is usually fatal within two years if left untreated.<br />

An estimated 12 million people are infected by leishmaniasis <strong>and</strong> around 2 million infections occur each year.<br />

Caused by a parasite which is transmitted via <strong>the</strong> bites of infected mosquitoes. Symptoms of malaria include fever,<br />

headache, <strong>and</strong> vomiting. If not treated, malaria can quickly become life-threatening. The majority of 1.5-2.5 million<br />

estimated annual deaths occur in sub-Saharan Africa.<br />

An inflammation of <strong>the</strong> lining of <strong>the</strong> brain <strong>and</strong> spinal cord, caused by bacterial infection. It can cause severe brain damage<br />

<strong>and</strong> is fatal in 50% of cases if untreated. The bacteria are transmitted from person to person through droplets of respiratory<br />

or throat secretions. The highest burden of meningococcal disease occurs in <strong>the</strong> region of sub-Saharan Africa known as<br />

<strong>the</strong> “Meningitis Belt” which stretches from Senegal east to Ethiopia<br />

A parasitic disease caused by flatworms which results in urinary or intestinal disease. Fresh water snails release a larval<br />

form of parasite that penetrates <strong>the</strong> skin of people exposed to contaminated water. Mortality, while generally low, may<br />

occur in advanced cases usually due to bladder cancer. 80% of infected people live in sub-Saharan Africa.


Box 2.2 Water security<br />

The array of complex factors that determine access to clean<br />

water – encompassing social, political <strong>and</strong> environmental<br />

<strong>issue</strong>s – means that <strong>the</strong> impacts on health have often not been<br />

well addressed. 66 The localised nature of water challenges<br />

<strong>and</strong> watershed management <strong>issue</strong>s add fur<strong>the</strong>r complexity.<br />

In some parts of <strong>the</strong> world <strong>the</strong>re will not be enough water; in<br />

o<strong>the</strong>rs <strong>the</strong>re will be too much. For example, predictions suggest<br />

that by 2025 climate change could lead to deficits in <strong>the</strong> water<br />

available from <strong>the</strong> Nile river basin, which covers three million<br />

square kilometres <strong>and</strong> ten Nor<strong>the</strong>rn African countries including<br />

Egypt, Sudan <strong>and</strong> Ethiopia. 67 Meanwhile many o<strong>the</strong>r parts of<br />

<strong>the</strong> world such as Bangladesh are at risk from rising sea levels.<br />

Today one in three people are already facing water shortages.<br />

Over <strong>the</strong> next twenty years global water dem<strong>and</strong> will outpace<br />

supply by 40 per cent. Under <strong>the</strong> pressure of potential effects<br />

of climate change, <strong>the</strong> stakes become even higher. Increased<br />

water temperatures <strong>and</strong> changes in extreme wea<strong>the</strong>r, including<br />

floods <strong>and</strong> droughts, are expected to affect water quality <strong>and</strong><br />

exacerbate water pollution. 68 This will hinder <strong>the</strong> use of water<br />

for hygiene purposes <strong>and</strong> affect food security. Increasing<br />

temperature also promotes <strong>the</strong> proliferation of microorganisms<br />

in contaminated food <strong>and</strong> drinking water.<br />

Projections for 2050 suggest that 38 per cent of <strong>the</strong> world<br />

population across 149 countries will live in water-scarce areas.<br />

The subtropics <strong>and</strong> mid latitudes, where much of <strong>the</strong> world’s<br />

poorest populations live, are expected to become substantially<br />

drier, resulting in heightened water scarcity. This will exacerbate<br />

<strong>the</strong> problem of malnutrition <strong>and</strong> lead to <strong>the</strong> increase of many<br />

waterborne diseases. Meanwhile, most existing water treatment<br />

plants <strong>and</strong> distribution systems were not built to withst<strong>and</strong><br />

changes now expected in precipitation <strong>and</strong> frequency of severe<br />

wea<strong>the</strong>r, 69 leaving <strong>the</strong> current infrastructure without <strong>the</strong> capacity<br />

to fully capture large volumes of water, or to meet water<br />

dem<strong>and</strong>s in times of sustained drought.<br />

<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

Figure 2.5: Eight infectious diseases that are sensitive to climate change<br />

Diseases<br />

Malaria<br />

Cholera<br />

Dengue<br />

Meningitis<br />

Leishmaniasis<br />

Influenza<br />

Diarrhoeal<br />

diseases<br />

Schistosomiasis<br />

Significance of climate<br />

change as a factor in<br />

determining future<br />

epidemics 1<br />

Primary<br />

Primary<br />

Important<br />

Important<br />

Important<br />

Significant<br />

Significant<br />

Significant<br />

Existing Global Burden 2<br />

(millions of DALYs lost)<br />

0.67<br />

33.98<br />

P<strong>and</strong>emic<br />

potential<br />

1.43<br />

1.97<br />

P<strong>and</strong>emic<br />

potential<br />

1.71<br />

72.78<br />

Countries affected<br />

Tropics, Sub-tropics<br />

Africa, Asia, Russia<br />

South America<br />

Africa, Europe, South<br />

America, South East Asia<br />

Worldwide<br />

Africa, Asia, Europe<br />

India, South America<br />

Worldwide<br />

Worldwide<br />

Africa, East Asia<br />

South America<br />

Source: 1.World <strong>Health</strong> Organization (WHO), 2005; Smith School Academic Review, 2. WHO, Global <strong>Health</strong> Observatory, Global Burden of Disease, 2004 (NB <strong>the</strong> Global Burden of Disease is an overall figure - not specific<br />

to climate change)<br />

The majority of infectious diseases that are most climate sensitive fall into <strong>the</strong> Neglected Tropical Disease (NTDs) category. Over 1 billion people are infected with one of <strong>the</strong> 14 diseases defined by <strong>the</strong> World <strong>Health</strong><br />

Organization (WHO) as NTDs – <strong>the</strong> world’s sixth leading cause of DALY loss. Although much attention in <strong>the</strong> past decade has focused on combating <strong>the</strong> ‘Big Three’ neglected diseases – HIV/AIDS, malaria, <strong>and</strong> tuberculosis<br />

– many of NTDs are often insufficiently funded from a Research <strong>and</strong> Development (R&D) perspective. In 2007, less than 5 per cent of US$2.5 billion in total funding for neglected diseases R&D went to NTDs. There are<br />

growing signs that <strong>the</strong> pharmaceutical industry is devoting more of <strong>the</strong>ir research <strong>and</strong> development efforts to NTDs by developing new products <strong>and</strong> supporting community initiatives. However, <strong>the</strong> extent to which <strong>the</strong>se<br />

responses factor in <strong>the</strong> diseases’ sensitivity to climate change remains uncertain. The World <strong>Health</strong> Organisation report assessed <strong>the</strong> significance of climate change as a factor in determining epidemics by looking at<br />

whe<strong>the</strong>r <strong>the</strong> climate-epidemic relationship has been successfully quantified. In <strong>the</strong> case of Malaria <strong>and</strong> Cholera, climate is <strong>the</strong> primary factor in determining at least some epidemics, <strong>and</strong> <strong>the</strong> strength of <strong>the</strong> association<br />

between climate <strong>and</strong> disease outbreaks has been assessed on <strong>the</strong> basis of published quantitative (statistical) ra<strong>the</strong>r than anecdotal evidence.<br />

What does <strong>the</strong> science say about <strong>the</strong> impact of climate change on health?<br />

21


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong> <strong>Health</strong>: <strong>Framing</strong> Paper <strong>the</strong> Issue<br />

3. Where will <strong>the</strong> impacts be most felt?<br />

The impacts of climate change on health will be felt most<br />

acutely in countries with low levels of gross domestic<br />

product (GDP) <strong>and</strong> low investment in health per capita.<br />

The countries that are most likely to be impacted by<br />

climate change are also <strong>the</strong> countries that suffer <strong>the</strong><br />

greatest health burden. South-East Asia <strong>and</strong> sub-Saharan<br />

Africa are most vulnerable to climate change <strong>and</strong> its<br />

health impacts.<br />

Developing countries 70 will suffer <strong>the</strong> most serious health<br />

impacts of climate change. Many of <strong>the</strong>se countries have<br />

climates that are among <strong>the</strong> most variable in <strong>the</strong> world<br />

<strong>and</strong> are susceptible to EWEs. Between 1990 <strong>and</strong> 1998,<br />

Regions most vulnerable to climate change<br />

The geographical regions of <strong>the</strong> world most vulnerable to climate<br />

change – namely South-East Asia <strong>and</strong> sub-Saharan Africa – are<br />

also likely to bear <strong>the</strong> largest health burden associated with it<br />

022Introduction<br />

22 Where will <strong>the</strong> impacts be most felt?<br />

94 per cent of <strong>the</strong> world’s 568 major natural disasters<br />

<strong>and</strong> more than 97 per cent of all natural disaster related<br />

deaths were in developing countries. 71<br />

The Maplecroft <strong>Climate</strong> <strong>Change</strong> Vulnerability Index rates<br />

166 countries according to six vulnerability factors:<br />

economy; national resource scarcity; ecosystems;<br />

poverty, development <strong>and</strong> health; population, settlement<br />

<strong>and</strong> infrastructure; institutions, governance <strong>and</strong> social<br />

capital. The Index found that Bangladesh, Burundi,<br />

Comoros, Rw<strong>and</strong>a, Haiti, Ethiopia, India, Afghanistan,<br />

Sierra Leone, <strong>and</strong> Pakistan are <strong>the</strong> ten countries currently<br />

most vulnerable to climate change. Africa has five of<br />

<strong>the</strong>se ten countries <strong>and</strong> seventy percent of <strong>the</strong> 20 most<br />

vulnerable (see Figure 3.1). 72<br />

94% of <strong>the</strong> world’s 568 natural<br />

disasters <strong>and</strong> more than 97 per cent of<br />

all natural disaster related deaths were in<br />

developing countries.<br />

(see Figure 3.2). In 2000 <strong>the</strong>se two regions accounted for over<br />

three quarters of <strong>the</strong> estimated global DALYs lost because<br />

of climate change. South-East Asia experienced <strong>the</strong> highest<br />

impact, with over 2.5 million DALYs lost, while Africa lost around<br />

1.8 million. This compares starkly with <strong>the</strong> 8,000 DALYs lost in<br />

developed countries.


Figure 3.1: Africa hosts 8 out of <strong>the</strong> 10 countries most vulnerable to climate change<br />

Maplecroft <strong>Climate</strong> <strong>Change</strong> Vulnerability Index (2010)<br />

Key<br />

Extreme<br />

High<br />

Medium<br />

Low<br />

Figure 3.2: South-East Asia <strong>and</strong> sub-Saharan Africa will bear <strong>the</strong> largest health burden<br />

Estimated impacts of climate change in 2000 by DALYs <strong>and</strong> WHO region, WHO (2003)<br />

Dev’d countries (8)<br />

Lat Am & Carrib (92)<br />

W.Pacific (169)<br />

E.Med (768)<br />

Africa Region (1984)<br />

S.E Asia (2572)<br />

(DALYs ‘000s)<br />

<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

Where will <strong>the</strong> impacts be most felt?<br />

23


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong> <strong>Health</strong>: <strong>Framing</strong> Paper <strong>the</strong> Issue<br />

Figure 3.3 Low GDP <strong>and</strong> investment in health<br />

correlate to climate change vulnerability<br />

<strong>Climate</strong> <strong>Change</strong> Score<br />

Ne<strong>the</strong>rl<strong>and</strong>s<br />

United Kingdom<br />

United States<br />

Norway<br />

Irel<strong>and</strong><br />

024Introduction<br />

24 Where will <strong>the</strong> impacts be most felt?<br />

High HD, High CCV Low HD, High CCV<br />

Cyprus<br />

Finl<strong>and</strong><br />

Bahrain<br />

Saudi Arabia<br />

Kuwait<br />

Russia<br />

Romania<br />

Lebanon<br />

South Africa<br />

Ecuador<br />

Legend - Regions (WHO)<br />

European Region<br />

Western Pacific Region<br />

South East Asia Region<br />

African Region<br />

Americas Region<br />

Eastern Mediterranean Region<br />

Size of bubble is proportional to <strong>the</strong> country’s GDP per Capita<br />

High HD, Low CCV Low HD, Low CCV<br />

<strong>Health</strong> Score<br />

China<br />

Philippines<br />

Indonesia<br />

Nigeria<br />

Gambia<br />

India<br />

Kenya<br />

Bangladesh<br />

Sources <strong>and</strong> approach: <strong>Climate</strong> <strong>Change</strong> Vulnerability Score ascertained through weighted averages of <strong>Climate</strong> <strong>Change</strong> Vulnerability Index (Maplecroft, 2011)<br />

<strong>and</strong> <strong>Climate</strong> Risk Index (Germanwatch, 2009). <strong>Health</strong> Expenditure per capita in 2007 (Government expenditure on health per capita, Purchasing Power Parity<br />

(PPP) international $, World <strong>Health</strong> Statistics 2010); GDP per capita (US$, ‘000s, World Bank, 2008)<br />

Pakistan<br />

Vulnerable countries typically have low<br />

levels of GDP <strong>and</strong> low investment in<br />

health per capita (see Figure 3.3).<br />

Four countries amongst this group –<br />

India, Bangladesh, Kenya <strong>and</strong> Angola<br />

– have been selected as case studies.<br />

These countries are amongst those<br />

that are vulnerable to climate change;<br />

<strong>the</strong>y have limited financial resources to<br />

deal with <strong>the</strong> health impacts of climate<br />

change <strong>and</strong> also have an increasing<br />

need for health care. Two countries<br />

each have been selected from different<br />

parts of South-East Asia <strong>and</strong> sub-<br />

Saharan Africa as <strong>the</strong>se are <strong>the</strong><br />

regions that are at most risk.


Country profiles<br />

INDIA<br />

<strong>Climate</strong>-change vulnerability HIGH<br />

<strong>Health</strong> expenditure per capita (Int. $ at PPP*) 29<br />

GDP per capita (US$) 1,017<br />

<strong>Climate</strong>-related health risks include: EWEs, vector-borne diseases such as malaria, water<br />

scarcity <strong>and</strong> malnutrition<br />

EWEs<br />

• India is at ‘extreme risk’ from natural disasters. 73 Natural disasters have caused nearly 150,000 deaths since<br />

1980 – with an average annual death toll of 3,255. 74<br />

• Heavy rainfall <strong>and</strong> flooding impacts health – particularly in urban areas. In July 2005, Mumbai had 944<br />

millimetres of rainfall in a 24-hour period (compared with <strong>the</strong> annual average of 21.7 centimetres of rainfall). 75<br />

The flooding was exacerbated by blocked canals <strong>and</strong> drains, causing an outbreak of infectious disease,<br />

such as cholera <strong>and</strong> typhoid fever, 76 with <strong>the</strong> prevalence of <strong>the</strong> vector-borne leptospirosis increasing eightfold. 77<br />

Disease<br />

• Malaria zones are predicted to spread to elevations above 1800m by 2080 owing to rising temperatures. 78<br />

• Access to clean water <strong>and</strong> water scarcity is an <strong>issue</strong> exacerbated by climate change – by 2050 <strong>the</strong>re could be<br />

an estimated 38 per cent potential drop in per capita water availability. 79<br />

<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

Natural disasters<br />

have caused nearly<br />

150,000<br />

deaths since 1980<br />

<strong>Health</strong> Expenditure per capita in 2007 - Government expenditure on health per capita, Purchasing Power Parity (PPP)* international $ (World <strong>Health</strong> Statistics, 2010); GDP per capita at current prices (US$),<br />

World Bank World Development Indicators 2008.<br />

* PPP (Purchasing Power Parity) is <strong>the</strong> exchange rate that equates <strong>the</strong> price of a basket of identical traded goods <strong>and</strong> services in two countries.<br />

Where will <strong>the</strong> impacts be most felt?<br />

25


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong> <strong>Health</strong>: <strong>Framing</strong> Paper <strong>the</strong> Issue<br />

BANGLADESH<br />

<strong>Climate</strong>-change vulnerability HIGH<br />

<strong>Health</strong> expenditure per capita (Int. $ at PPP*) 14<br />

GDP per capita (US$) 497<br />

<strong>Climate</strong>-related health risks include: EWEs, TB, malnutrition, dengue fever, diarrhoea<br />

<strong>and</strong> Hepatitis A<br />

EWEs<br />

• Bangladesh is at extreme risk from rising sea levels <strong>and</strong> flooding – <strong>and</strong> forced migration is likely to exacerbate<br />

communicable diseases.<br />

• Bangladesh suffered eight major floods between 1974 <strong>and</strong> 2004, <strong>the</strong> 1998 flood alone affecting 30 million<br />

people <strong>and</strong> inflicting losses of US$3 billion. 80<br />

• The direct annual cost of natural disasters over <strong>the</strong> last 10 years is estimated to be between 0.5% <strong>and</strong> 1% of<br />

Bangladesh’s GDP. 81<br />

Disease<br />

• Food or waterborne diseases are common in Bangladesh - bacterial <strong>and</strong> protozoal diarrhoea, hepatitis A <strong>and</strong> E,<br />

<strong>and</strong> typhoid fever are especially common.<br />

• Vector-borne diseases – especially dengue fever <strong>and</strong> malaria – are high risks in some locations. Out of 64<br />

districts in Bangladesh, 13 are classified as being in a high-risk malarial zone. A total of 14.7 million people in<br />

Bangladesh are classified as high-risk in terms of catching malaria. 82<br />

Major floods in 1998 affected 30 million people<br />

026Introduction<br />

26 Where will <strong>the</strong> impacts be most felt?


KENYA<br />

<strong>Climate</strong>-change vulnerability HIGH<br />

<strong>Health</strong> expenditure per capita (Int. $ at PPP*) 30<br />

GDP per capita (US$) 783<br />

<strong>Climate</strong>-related health risks include: Malaria, NTDs <strong>and</strong> water scarcity<br />

EWEs<br />

• Kenya is susceptible to a number of natural hazards, including floods, droughts, l<strong>and</strong>slides <strong>and</strong> wild fires. 83<br />

• Drought is <strong>the</strong> most common natural hazard; almost 70 per cent of Kenya’s l<strong>and</strong> mass is affected by drought. 84<br />

In <strong>the</strong> areas of Kenya most affected by drought in <strong>the</strong> arid north of <strong>the</strong> country up to 30 per cent of children<br />

are malnourished. 85<br />

• Floods seasonally affect various parts of <strong>the</strong> country. 86 The most severe floods in 1997–98 affected<br />

1.5 million people. 87<br />

Disease<br />

• Kenya has a high degree of risk from climate-sensitive infectious diseases such as food or waterborne diseases<br />

like diarrhoea, hepatitis A, <strong>and</strong> typhoid fever. Vector-borne diseases such as malaria, dengue fever, <strong>and</strong> Rift<br />

Valley Fever are also common. 88<br />

• High temperatures <strong>and</strong> intense rainfall events are known to be critical factors in initiating malaria epidemics in<br />

East Africa. 89 Malaria affects 20 million individuals annually in Kenya <strong>and</strong> costs an overall production loss of two<br />

to six per cent of GDP.<br />

• In <strong>the</strong> 1997 <strong>and</strong> 2006 El Niño seasons, Rift Valley Fever (RVF) caused major outbreaks in livestock <strong>and</strong> human<br />

populations. From 30 November 2006 to 12 March 2007 a total of 684 cases of RVF, including 155 deaths,<br />

were reported in Kenya; a case-fatality ratio of 23 per cent. 90<br />

<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

Almost 70% of<br />

Kenya’s l<strong>and</strong> mass is<br />

affected by drought<br />

Where will <strong>the</strong> impacts be most felt?<br />

27


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong> <strong>Health</strong>: <strong>Framing</strong> Paper <strong>the</strong> Issue<br />

ANGOLA<br />

<strong>Climate</strong>-change vulnerability HIGH<br />

<strong>Health</strong> expenditure per capita (Int. $ at PPP*) 105<br />

GDP per capita (US$) 4,714<br />

<strong>Climate</strong>-related health risks include: EWEs, diarrhoea, hepatitis A, malaria,<br />

<strong>and</strong> schistosomiasis<br />

EWEs<br />

• There has been an increase in <strong>the</strong> number of warm spells over Sou<strong>the</strong>rn Africa <strong>and</strong> a decrease in <strong>the</strong> number<br />

of extremely cold days. In some parts of Sou<strong>the</strong>rn Africa, including Angola, a significant increase in heavy<br />

rainfall events has been observed along with evidence for changes in seasonality <strong>and</strong> extremes. 91<br />

• Locally heavy rainfall causes periodic flooding on Angola’s interior plateau. 92 In 2009, about 80,000 people were<br />

displaced from <strong>the</strong>ir homes <strong>and</strong> 220,000 people were affected by floods in <strong>the</strong> sou<strong>the</strong>rn Angolan province of<br />

Cunene. 93<br />

Disease<br />

• The entire population of Angola is considered at risk of malaria. 94<br />

• Angola has a ‘very high’ risk rating for a number of o<strong>the</strong>r major climate-sensitive infectious diseases: food or<br />

waterborne diseases such as bacterial <strong>and</strong> protozoal diarrhoea, hepatitis A, typhoid fever; vector-borne diseases<br />

such as African trypanosomiasis (sleeping sickness); <strong>and</strong> water contact diseases such as schistosomiasis. 95<br />

• Cholera <strong>and</strong> respiratory infections also increased dramatically after recent floods. 96<br />

028Introduction<br />

28 Where will <strong>the</strong> impacts be most felt?<br />

In 2009, about<br />

80,000 people<br />

were displaced<br />

from <strong>the</strong>ir homes.


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

4. What are <strong>the</strong> societal <strong>and</strong> economic<br />

benefits of addressing climate change<br />

related health impacts?<br />

Tackling <strong>the</strong> health impacts of climate change will have a<br />

positive impact on society, but also on <strong>the</strong> economy.<br />

• Societal benefits: Most importantly, tackling <strong>the</strong> impacts<br />

of climate change on health will alleviate <strong>the</strong> human<br />

costs of pain <strong>and</strong> suffering, allow resources to be<br />

allocated to education, <strong>and</strong> support development.<br />

• Economic benefits: Although <strong>the</strong> impact on disease<br />

<strong>and</strong> human health is <strong>the</strong> most important benefit, <strong>the</strong>re<br />

are also economic rewards at stake. The net economic<br />

benefits of managing climate change related incidents<br />

of malaria, malnutrition <strong>and</strong> diarrhoeal disease in<br />

sub-Saharan Africa <strong>and</strong> South-East Asian economies<br />

could range from US$33–US$54 billion between<br />

2010 <strong>and</strong> 2030. 97<br />

Even if global emissions of GHGs are drastically reduced<br />

in <strong>the</strong> coming years, temperatures are none<strong>the</strong>less<br />

expected to rise. The health impacts of climate change<br />

will need to be addressed through prevention, treatment<br />

<strong>and</strong> adaptation.<br />

Tackling <strong>the</strong> health impacts of climate change will have<br />

a positive impact both on society <strong>and</strong> on <strong>the</strong> economy.<br />

<strong>Health</strong> interventions will alleviate some of <strong>the</strong> human<br />

suffering involved, including loss, pain <strong>and</strong> bereavement.<br />

It is impossible to quantify this benefit, but it none<strong>the</strong>less<br />

remains <strong>the</strong> primary consideration in <strong>the</strong> fight against disease.<br />

In considering <strong>the</strong> benefits of addressing <strong>the</strong> health<br />

impacts of climate change it is also important to bear in<br />

mind <strong>the</strong> alleviation of strain for individuals <strong>and</strong> countries.<br />

At a national level, developing countries with already<br />

limited resources are fur<strong>the</strong>r stretched by <strong>the</strong> pressures<br />

on public health systems.<br />

Meanwhile at <strong>the</strong> household level, families will often divert<br />

spending towards medicine at <strong>the</strong> expense of o<strong>the</strong>r<br />

basic needs. Reducing <strong>the</strong> disease burden would allow<br />

resources to be directed to o<strong>the</strong>r activities – for example<br />

education – that can improve both quality of life <strong>and</strong><br />

future earning prospects.<br />

Benefits also extend to <strong>the</strong> wider international health<br />

<strong>and</strong> development agenda. Four of <strong>the</strong> United Nations’<br />

Millennium Development Goals (MDGs) – although<br />

underpinned by wider economic factors – relate<br />

specifically to health <strong>and</strong>/or climate change. The goals to<br />

eradicate extreme poverty <strong>and</strong> hunger (goal 1), reduce<br />

child mortality rate (goal 4), combat HIV/AIDS, malaria<br />

<strong>and</strong> o<strong>the</strong>r diseases (goal 6) <strong>and</strong> ensure environmental<br />

sustainability (goal 7) could all be impacted by <strong>the</strong> health<br />

effects of climate change. Limiting GHGs <strong>and</strong> ensuring<br />

that any additional health impacts from climate change<br />

are addressed will contribute significantly to fur<strong>the</strong>ring<br />

<strong>the</strong> MDGs.<br />

The net economic benefits of managing <strong>the</strong><br />

additional health effects of climate change will<br />

also be significant.<br />

What are <strong>the</strong> societal <strong>and</strong> economic benefits of addressing climate change related health impacts?<br />

29


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong> <strong>Health</strong>: <strong>Framing</strong> Paper <strong>the</strong> Issue<br />

Disease can lead to death or disability, preventing an<br />

individual from taking part in productive economic activity.<br />

Therefore each life saved – or each individual restored<br />

to health through a health intervention – represents a<br />

benefit to <strong>the</strong> economy. It opens up <strong>the</strong> possibility that<br />

<strong>the</strong> individual will remain in (or enter) <strong>the</strong> labour force <strong>and</strong><br />

contribute to economic output.<br />

Initial analysis, albeit based on limited data, indicates that<br />

<strong>the</strong> net economic benefits of managing <strong>the</strong> climate change<br />

related incidence of malaria, malnutrition <strong>and</strong> diarrhoeal<br />

disease in <strong>the</strong> sub-Saharan African <strong>and</strong> South-East Asian<br />

economies are expected to range from US$33–US$54<br />

billion from 2010 to 2030 (Figure 4.1). This represents<br />

between 0.6 per cent <strong>and</strong> 1.0 per cent of current GDP for<br />

<strong>the</strong>se regions; a significant benefit, particularly in light of<br />

<strong>the</strong> prevalent poverty in many of <strong>the</strong>se countries. The total<br />

annual benefit is based on <strong>the</strong> additional economic output<br />

that is gained from managing <strong>the</strong> diseases.<br />

From this indicative analysis, South-East Asian economies<br />

are estimated to yield <strong>the</strong> greatest net benefit in absolute<br />

terms. However, Sub-Saharan African economies will feel<br />

<strong>the</strong> benefit of tackling <strong>the</strong>se <strong>issue</strong>s <strong>the</strong> most owing to<br />

<strong>the</strong>ir current low levels of GDP. Benefits vary by disease<br />

<strong>and</strong> by climate change scenario. If a medium climate<br />

change scenario is taken as <strong>the</strong> most likely outcome,<br />

tackling climate change related malaria incidents across<br />

<strong>the</strong>se two regions could yield a net economic benefit of<br />

approximately US$14 billion, with most of this benefit<br />

arising in sub-Saharan Africa. For diarrhoeal diseases <strong>the</strong><br />

net benefit across <strong>the</strong>se two regions would be around<br />

US$6 billion <strong>and</strong> for malnutrition it would be US$23 billion.<br />

The analysis, although dealing with <strong>the</strong> marginal impact<br />

of climate change, points to <strong>the</strong> benefits that would arise<br />

from treating <strong>the</strong> wider pool of disease (see Appendix 1<br />

for more detail).<br />

030Introduction<br />

30 What are <strong>the</strong> societal <strong>and</strong> economic benefits of addressing climate change related health impacts?<br />

Figure 4.1: The cumulative economic benefit of tackling <strong>the</strong> impacts of climate<br />

change on health could be significant<br />

Net positive economic benefit of tackling <strong>the</strong> health impacts of climate change on malaria, malnutrition<br />

<strong>and</strong> diarrhoeal disease by 2030<br />

Source: Accenture Analysis (for a breakdown of <strong>the</strong> methodology, countries covered in <strong>the</strong> analysis,<br />

<strong>and</strong> o<strong>the</strong>r variables, please see Appendix 1)<br />

Malaria<br />

Malnutrition<br />

Diarrhoeal<br />

diseases<br />

<strong>Climate</strong> change scenario<br />

Impact on GDP$bn<br />

Sub-Saharan<br />

Africa<br />

South East Asia<br />

Sub-Saharan<br />

Africa<br />

South East Asia<br />

Sub-Saharan<br />

Africa<br />

South East Asia<br />

Low Medium High<br />

12<br />

Summary of total Net Benefit<br />

Note: <strong>Climate</strong> change scenarios are adapted from <strong>the</strong> three alternative emissions scenarios used by <strong>the</strong> World <strong>Health</strong><br />

Organization Global Burden of Disease Study (2003). Additional incidence of disease taken from Ebi (2008). 98<br />

14<br />

– Negligible Negligible<br />

2 3 1<br />

15<br />

24<br />

20 20<br />

4 6 7<br />

0.5 0.6 0.7<br />

Total GDP Impact<br />

The net bene�t to <strong>the</strong>se regions of<br />

managing <strong>the</strong> additional climate<br />

change related cases of Malaria could<br />

correspond to 0.2-0.4% of GDP<br />

Total GDP Impact<br />

The net bene�t to <strong>the</strong>se regions<br />

of managing <strong>the</strong> additional climate<br />

change related cases of Malnutrition<br />

could correspond to 0.3-0.4% of GDP<br />

Total GDP Impact<br />

The net bene�t to <strong>the</strong>se regions of<br />

managing <strong>the</strong> additional climate change<br />

related cases of Diarrhoeal disease<br />

could correspond to 0.1% of GDP


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

5. What are <strong>the</strong> impacts <strong>and</strong> implications<br />

for <strong>the</strong> pharmaceutical industry?<br />

The current underst<strong>and</strong>ing of <strong>the</strong> impact of climate<br />

change on health suggests that this <strong>issue</strong> is unlikely<br />

to lead to fundamental changes in <strong>the</strong> pharmaceutical<br />

business model – at least in <strong>the</strong> short term.<br />

However, <strong>the</strong>re are a number of factors which will<br />

influence <strong>the</strong> pharmaceutical industry in <strong>the</strong> more<br />

immediate future. These include increasing dem<strong>and</strong><br />

for healthcare products within emerging markets,<br />

improving access to medicine in <strong>the</strong> developing world,<br />

an increasingly stringent regulatory <strong>and</strong> operating<br />

environment, <strong>and</strong> a drop in innovation <strong>and</strong> R&D<br />

productivity, as well as <strong>the</strong> growing need for research<br />

<strong>and</strong> development on NTDs. Improvements in healthcare<br />

information technology <strong>and</strong> an increase in targeted<br />

treatment solutions are also likely to be more important<br />

areas of focus for <strong>the</strong> industry.<br />

5.1 Impacts<br />

Despite o<strong>the</strong>r immediate – <strong>and</strong> seemingly more pressing<br />

– <strong>issue</strong>s, it is imperative that we start to frame <strong>the</strong> debate<br />

around what <strong>the</strong> potential impacts <strong>and</strong> implications of<br />

climate change are for <strong>the</strong> pharmaceutical industry over<br />

<strong>the</strong> longer term. Doing this makes successful mitigation,<br />

response <strong>and</strong> adaptation to risks more likely. The following<br />

section highlights potential impacts identified to date in<br />

relation to four key areas:<br />

• Stakeholder relations: The breadth of stakeholders<br />

<strong>the</strong> industry needs to interact with on this <strong>issue</strong><br />

will increase<br />

• Strategic planning: Current uncertainty will continue<br />

to make strategic choices <strong>and</strong> planning on this<br />

<strong>issue</strong> difficult<br />

• Skills: New skills may be required to respond to<br />

climate change impacts<br />

• Supply chains: Pharmaceutical supply chains could<br />

be affected<br />

Stakeholder relations<br />

Building trust <strong>and</strong> reputation is a key priority for <strong>the</strong><br />

pharmaceutical industry. The breadth of <strong>issue</strong>s <strong>and</strong><br />

stakeholder groups with which pharmaceutical<br />

organisations may wish to interact <strong>and</strong> develop a<br />

trusted relationship is likely to increase in coming years<br />

as climate change starts to impact health. These <strong>issue</strong>s<br />

could range from intellectual property rights to <strong>the</strong> R&D<br />

agenda, as well as <strong>the</strong> contribution pharma is making to<br />

climate change adaptation. Pharmaceutical companies<br />

may need to develop closer partnerships with NGOs,<br />

government agencies <strong>and</strong> o<strong>the</strong>r stakeholders. This move<br />

away from traditional stakeholders is a general industry<br />

trend as <strong>the</strong> role of pharmacists, payers <strong>and</strong> patients<br />

increases. The impact of climate change on health could<br />

accelerate this trend.<br />

There is increasing stakeholder dem<strong>and</strong> for<br />

pharmaceutical companies to quantify <strong>the</strong> benefits<br />

<strong>the</strong>y have on <strong>the</strong> bottom line, as well as to society<br />

more broadly. This may mean that a more focused <strong>and</strong><br />

proactive approach to tackling climate change impacts<br />

on health is required. As a result, some existing activities<br />

will increase in importance <strong>and</strong> come under more intense<br />

stakeholder scrutiny; for example building trust <strong>and</strong><br />

reputation, examining intellectual property, access to<br />

medicines <strong>and</strong> preferential pricing schemes.<br />

What are <strong>the</strong> impacts <strong>and</strong> implications for <strong>the</strong> pharmaceutical industry?<br />

31


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong> <strong>Health</strong>: <strong>Framing</strong> Paper <strong>the</strong> Issue<br />

Strategic planning<br />

Uncertainty <strong>and</strong> lack of granularity in <strong>the</strong> data around<br />

climate change <strong>and</strong> health might present strategic<br />

difficulties for organisations <strong>and</strong> for <strong>the</strong> pharmaceutical<br />

industry as a whole. Particular challenges include <strong>the</strong><br />

ability to:<br />

• Make strategic choices based on climate change<br />

<strong>and</strong> health<br />

• Undertake informed choices on future R&D priorities<br />

<strong>and</strong> plans<br />

• Model <strong>the</strong> impact of climate change on disease<br />

epidemiology <strong>and</strong> <strong>the</strong> cost-effectiveness of products<br />

• Develop appropriate pricing <strong>and</strong> marketing approaches<br />

• Plan appropriate supply <strong>and</strong> distribution; how much is<br />

required, where <strong>and</strong> when<br />

The limitations presented by uncertainty <strong>and</strong> <strong>the</strong> lack of<br />

specificity in research on climate change <strong>and</strong> health are<br />

probably <strong>the</strong> biggest risks of all at present.<br />

Skills<br />

<strong>Climate</strong> change is unlikely to have a significant impact<br />

on <strong>the</strong> individual skills required within <strong>the</strong> majority of<br />

pharmaceutical company functions. There may be<br />

increased dem<strong>and</strong> for infectious disease specialists<br />

(scientists, researchers, medics, statisticians, etc), but<br />

<strong>the</strong> degree of change is likely to be minimal <strong>and</strong> over a<br />

prolonged period; o<strong>the</strong>r portfolio changes are likely to<br />

have a greater, <strong>and</strong> more immediate, impact on <strong>the</strong> mix<br />

of specialism required.<br />

The more likely scenario is that a new blend of skills<br />

will be required across <strong>the</strong> organisation, for example<br />

partnering <strong>and</strong> interdisciplinary cooperation with various<br />

stakeholders involved in <strong>the</strong> climate change <strong>and</strong> health<br />

032Introduction<br />

32 What are <strong>the</strong> impacts <strong>and</strong> implications for <strong>the</strong> pharmaceutical industry?<br />

debate. This is likely to include healthcare professionals,<br />

climate experts, biologists <strong>and</strong> social scientists, as well<br />

as governmental <strong>and</strong> multilateral organisations, NGOs,<br />

community groups, etc.<br />

Supply chains<br />

Finally, although <strong>the</strong> evidence is limited, it is conceivable<br />

that climate change could present a risk to <strong>the</strong> supply<br />

chain. One risk is <strong>the</strong> potential for disruption in <strong>the</strong><br />

availability of raw materials; decreased biodiversity as a<br />

consequence of climate change will have an impact on<br />

current <strong>and</strong> new drug development. Ano<strong>the</strong>r instance<br />

is <strong>the</strong> potential impact on distribution networks for <strong>the</strong><br />

onward delivery of finished product. Product supply could<br />

also possibly be compromised during climate induced<br />

crises or sudden disease spread. The potential risks <strong>and</strong><br />

impacts, however, are not well understood.<br />

5.2 Developing a response<br />

Pharmaceutical executives might consider <strong>the</strong> following<br />

critical questions as <strong>the</strong>y address <strong>the</strong> implications of<br />

climate change <strong>and</strong> health for <strong>the</strong>ir organisation:<br />

• Which stakeholders does <strong>the</strong> industry need to engage<br />

with around climate change <strong>and</strong> health? What is <strong>the</strong><br />

most appropriate forum for collaboration?<br />

• What tools <strong>and</strong> methods can be used to factor<br />

uncertainties into corporate planning? How can climate<br />

change be added as a variable to ensure adequate<br />

preparation for both acute <strong>and</strong> sudden impacts?<br />

• What research methods <strong>and</strong> data already exist that<br />

can be used to model <strong>the</strong> impact of different climate<br />

scenarios on specific diseases?<br />

• What is <strong>the</strong> best means of ga<strong>the</strong>ring new data on<br />

disease burden <strong>and</strong> unmet needs?<br />

By embedding<br />

vigilance, flexibility<br />

<strong>and</strong> adaptability into<br />

business models,<br />

organisations will be<br />

better placed to meet<br />

customer needs in <strong>the</strong><br />

face of <strong>the</strong> changing<br />

environment.<br />

• How can R&D be geared towards lessening <strong>the</strong> health<br />

impacts of climate change as well as addressing patient<br />

needs?<br />

• How can organisations most effectively work with<br />

governments, regulatory bodies <strong>and</strong> o<strong>the</strong>r agencies to<br />

create a common language <strong>and</strong> underst<strong>and</strong>ing around<br />

<strong>the</strong> <strong>issue</strong>s <strong>and</strong> possible solutions?<br />

• How will climate change affect <strong>the</strong> sales of different<br />

products <strong>and</strong> services? What changes, if any, are<br />

required to <strong>the</strong> sales <strong>and</strong> marketing function to meet<br />

this dem<strong>and</strong> <strong>and</strong> address patient needs?<br />

• Which manufacturing sites/supply chains/distribution<br />

networks are dependent on parts of <strong>the</strong> world that are<br />

susceptible to both <strong>the</strong> impacts of climate change <strong>and</strong><br />

its associated health effects? How can <strong>the</strong>y be made<br />

more resilient?


5.3 Implications<br />

Given <strong>the</strong> gaps in our knowledge <strong>and</strong> many of <strong>the</strong><br />

remaining uncertainties, we see <strong>the</strong> response of <strong>the</strong><br />

industry covering four key areas:<br />

• Engaging stakeholders: Working toge<strong>the</strong>r with multiple<br />

stakeholders to increase awareness <strong>and</strong> underst<strong>and</strong>ing<br />

around <strong>the</strong> <strong>issue</strong> of climate change <strong>and</strong> health<br />

• Building resilience: Partnering with <strong>the</strong> broader health<br />

community to integrate climate change resilience into<br />

existing activities<br />

• Driving science <strong>and</strong> innovation: Contributing to <strong>the</strong><br />

global research agenda around climate change<br />

<strong>and</strong> health<br />

• Being prepared to respond: Integrating climate change<br />

<strong>and</strong> health as an additional consideration in future<br />

planning<br />

Engaging stakeholders: Stakeholder interest on climate<br />

change <strong>and</strong> health already exists <strong>and</strong> is growing. For<br />

example <strong>the</strong> number of articles on climate change <strong>and</strong><br />

health (still an emerging area of research) has increased<br />

significantly in <strong>the</strong> past decade (see Figure 5.1).<br />

There will be a good opportunity for <strong>the</strong> pharmaceutical<br />

industry, healthcare professionals, policy makers <strong>and</strong><br />

wider society to come toge<strong>the</strong>r to discuss <strong>the</strong> challenges<br />

<strong>and</strong> opportunities presented by climate change <strong>and</strong><br />

health. At <strong>the</strong> very least, this will help to build trust <strong>and</strong><br />

communication. At best it will lead to innovative solutions,<br />

shared benefits, <strong>and</strong> collective awareness regarding an<br />

uncertain future.<br />

Figure 5.1: Academic interest in climate<br />

change <strong>and</strong> health is growing<br />

Number of academic articles with ‘climate change’<br />

<strong>and</strong> ‘human health’ in <strong>the</strong> article title, abstract or<br />

body text<br />

<strong>Climate</strong> change <strong>and</strong> health article count<br />

250<br />

200<br />

150<br />

100<br />

50<br />

0<br />

1980 1995 2010<br />

Year<br />

Source: Scopus article search (as of May 2011)<br />

<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

Practical steps to engage with stakeholders<br />

could involve:<br />

• Initiating or co-developing a forum of key stakeholders<br />

to discuss <strong>the</strong> implications of climate change on health<br />

for a broad range of health-related sectors. Policy<br />

makers, NGOs, multilateral organisations, local health<br />

<strong>and</strong> environmental agencies as well as <strong>the</strong> private<br />

sector will be critical to <strong>the</strong> success of any such<br />

dialogue<br />

• Engaging in open dialogue with a wider audience<br />

through public engagement <strong>and</strong> advocacy<br />

• Developing communication <strong>and</strong> education materials.<br />

These could outline <strong>the</strong> key <strong>issue</strong>s <strong>and</strong> explain actions<br />

being taken by <strong>the</strong> industry to underst<strong>and</strong> <strong>and</strong> tackle<br />

<strong>the</strong> impact of climate change on health<br />

Building resilience: The impacts of climate change<br />

<strong>and</strong> health will be both gradual <strong>and</strong> sudden. For some<br />

health impacts it could be decades before <strong>the</strong> impact of<br />

climate change is felt. For o<strong>the</strong>rs such as EWEs or new<br />

emerging diseases <strong>the</strong> effect could be sudden <strong>and</strong> come<br />

without warning.<br />

Ensuring health systems have <strong>the</strong> capacity to deal<br />

with change <strong>and</strong> continue to function in this context<br />

becomes essential. This is a particular consideration<br />

for, but not isolated to, many emerging <strong>and</strong> developing<br />

countries where weak healthcare infrastructure is already<br />

strained. Integrating climate change resilience into<br />

<strong>the</strong> development of healthcare systems will improve<br />

accessibility <strong>and</strong> availability of services when <strong>the</strong>y are<br />

needed <strong>the</strong> most. Although this is not <strong>the</strong> primary<br />

responsibility of <strong>the</strong> pharmaceutical industry, <strong>the</strong>re is<br />

a role for <strong>the</strong> industry to play as part of <strong>the</strong> broader<br />

community engaged in supporting public health systems.<br />

What are <strong>the</strong> impacts <strong>and</strong> implications for <strong>the</strong> pharmaceutical industry?<br />

33


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong> <strong>Health</strong>: <strong>Framing</strong> Paper <strong>the</strong> Issue<br />

Building capacity to ‘bounce back’, for example to<br />

respond efficiently <strong>and</strong> quickly after EWEs, is also relevant<br />

for organisations in <strong>the</strong> health <strong>and</strong> pharmaceutical<br />

sector, where continuity is essential for saving lives.<br />

By embedding vigilance, flexibility <strong>and</strong> adaptability into<br />

business models, organisations will be better placed<br />

to meet customer needs in <strong>the</strong> face of <strong>the</strong> changing<br />

environment.<br />

Practical steps to build resilience could involve:<br />

• Helping to ensure climate change is embedded into<br />

existing financial <strong>and</strong>/or technical support for capacity<br />

building <strong>and</strong> infrastructure development in emerging<br />

<strong>and</strong> developing markets<br />

• Assisting in <strong>the</strong> development of disaster contingency<br />

plans for healthcare systems in both <strong>the</strong> developed <strong>and</strong><br />

developing world<br />

• Adding climate change as an additional consideration<br />

in strategic planning <strong>and</strong> operating models to allow<br />

continual adaptation to <strong>the</strong> evolving environment<br />

• Creating a climate change resilient supply chain to<br />

provide surety of supply for consumers<br />

Driving science <strong>and</strong> innovation: Lack of data is one of<br />

<strong>the</strong> biggest barriers to decision-making around climate<br />

change <strong>and</strong> health. The pharmaceutical industry could<br />

contribute to fur<strong>the</strong>ring <strong>the</strong> knowledge base by engaging<br />

in <strong>the</strong> global research agenda on this <strong>issue</strong>. Addressing<br />

some of <strong>the</strong> gaps in <strong>the</strong> existing body of knowledge<br />

will not only increase levels of underst<strong>and</strong>ing, it will also<br />

enable its resources <strong>and</strong> public policies to be targeted<br />

appropriately.<br />

034Introduction<br />

34 What are <strong>the</strong> impacts <strong>and</strong> implications for <strong>the</strong> pharmaceutical industry?<br />

National <strong>and</strong> community-based monitoring <strong>and</strong> surveillance<br />

in particular will increase <strong>the</strong> knowledge of how climate<br />

change is affecting human health, now <strong>and</strong> in <strong>the</strong> future.<br />

This is no simple undertaking; it is likely to require a range<br />

of efforts, insights, expertise <strong>and</strong> finance from <strong>the</strong> private<br />

<strong>and</strong> public sector, academia <strong>and</strong> civil society.<br />

Practical steps to drive science <strong>and</strong> innovation<br />

could involve:<br />

• Using <strong>the</strong> pharmaceutical industry’s knowledge to<br />

contribute to <strong>the</strong> knowledge base on climate change<br />

<strong>and</strong> health<br />

• Partnering with academia, local communities <strong>and</strong><br />

government to support a <strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong><br />

Observatory, with a specific focus on emerging <strong>and</strong><br />

developing markets. The remit of such an observatory<br />

could involve:<br />

• Building monitoring <strong>and</strong> early-warning systems using<br />

climate change metrics <strong>and</strong> thresholds for key diseases<br />

• Putting in place metric tracking <strong>and</strong> management<br />

capabilities<br />

• Creating a repository or database to collect information<br />

• Developing climate change guidance for <strong>the</strong> healthcare<br />

industry <strong>and</strong> o<strong>the</strong>r interested parties<br />

• Building skills <strong>and</strong> knowledge<br />

• Advocating governments to provide funding for<br />

research into climate change <strong>and</strong> its impact on disease<br />

pathways <strong>and</strong> epidemiology<br />

Being prepared to respond: The interplay between<br />

climate change <strong>and</strong> health should be added as<br />

a consideration in <strong>the</strong> strategic planning <strong>and</strong> risk<br />

management activities of <strong>the</strong> pharmaceutical industry.<br />

Continued monitoring <strong>and</strong> exploration will help <strong>the</strong><br />

industry manage <strong>the</strong> uncertainty associated with climate<br />

change <strong>and</strong> health. It will also enable <strong>the</strong> industry to<br />

become more aware of potential future events <strong>and</strong> be<br />

better prepared to respond to a range of possibilities.<br />

Practical steps to ensure <strong>the</strong> industry is prepared to<br />

respond could include:<br />

• Adding climate change <strong>and</strong> health as a consideration in<br />

strategic planning <strong>and</strong> risk management activities<br />

• Using horizon scanning <strong>and</strong> scenario planning to<br />

monitor <strong>and</strong> explore <strong>the</strong> uncertainty associated with<br />

climate change <strong>and</strong> health<br />

• Ensuring R & D priorities factor in <strong>the</strong> impact of climate<br />

change on infectious diseases. This should especially<br />

include those that are particularly climate sensitive,<br />

including many neglected tropical diseases<br />

• Examining how climate change could affect <strong>the</strong> health<br />

l<strong>and</strong>scape in emerging <strong>and</strong> developing markets<br />

• Underst<strong>and</strong>ing where <strong>the</strong> pharmaceutical industry can<br />

have <strong>the</strong> greatest impact <strong>and</strong> what <strong>the</strong> industry’s role<br />

should be on <strong>the</strong> <strong>issue</strong>


Conclusion<br />

Science tells us that change is happening.<br />

It also suggests that climate change will<br />

exacerbate existing health <strong>issue</strong>s – most<br />

notably in <strong>the</strong> developing world.<br />

However, current knowledge has only begun to scratch<br />

<strong>the</strong> surface of what <strong>the</strong> impacts of climate change on<br />

health could be. Gaps remain in our underst<strong>and</strong>ing of<br />

<strong>the</strong> health impacts of climate change at a local <strong>and</strong> often<br />

disease-specific level.<br />

Most importantly,<br />

we invite stakeholders<br />

to work with us to<br />

use this as a starting<br />

point for action <strong>and</strong><br />

collaboration.<br />

Like all big enterprises, companies in <strong>the</strong> pharmaceutical<br />

industry need to reduce <strong>the</strong>ir GHGs to contribute to <strong>the</strong><br />

global efforts to mitigate against <strong>the</strong> effects of climate<br />

change. Additionally, from a health perspective, <strong>the</strong><br />

industry has an important role to play in helping society<br />

adapt <strong>and</strong> respond to <strong>the</strong> changing climate.<br />

By working with society to reduce knowledge gaps,<br />

engaging with a wide range of stakeholders, continuing<br />

to bolster healthcare systems <strong>and</strong> improving access to<br />

medicine in <strong>the</strong> developing world, both society <strong>and</strong> <strong>the</strong><br />

pharmaceutical industry will be better prepared to adapt<br />

to an uncertain future.<br />

GSK, Accenture <strong>and</strong> <strong>the</strong> Smith School of Enterprise<br />

<strong>and</strong> <strong>the</strong> Environment welcome partnership on this <strong>issue</strong>,<br />

particularly to examine <strong>the</strong> existing knowledge gaps <strong>and</strong><br />

to begin to answer some of <strong>the</strong> questions identified. Most<br />

importantly, we invite stakeholders to work with us to use<br />

this as a starting point for action <strong>and</strong> collaboration.<br />

<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

Conclusion<br />

35


<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

Acknowledgements<br />

We would like to thank <strong>the</strong> following external experts for <strong>the</strong>ir contributions to this report.<br />

Professor Anthony McMichael Australian National University<br />

Ben Schwartz Care International<br />

Maryann Delea Care International<br />

Madeleine Thomson International Research Institute for <strong>Climate</strong> <strong>and</strong> Society,<br />

Columbia University<br />

Daniel Osgood International Research Institute for <strong>Climate</strong> <strong>and</strong> Society,<br />

Columbia University<br />

Professor Walter Leal Filho Hamburg University of Applied Sciences<br />

Professor Paul Epstein Harvard University<br />

Professor Sir Roy Anderson Imperial College, London<br />

A.J.M. (Ton) Hoek International Pharmaceutical Federation<br />

Professor Rais Akhtar Jawaharlal Nehru University, New Delhi<br />

Professor Andrew Haines London School of Hygiene <strong>and</strong> Tropical Medicine<br />

Dr Paul Wilkinson London School of Hygiene <strong>and</strong> Tropical Medicine<br />

Professor David Mat<strong>the</strong>ws Oxford Centre for Diabetes, Endocrinology <strong>and</strong><br />

Metabolism<br />

Christopher Elias PATH<br />

Sophia Tickell Meteos<br />

Dr Manjinder S<strong>and</strong>hu University of Cambridge<br />

Professor Anthony Costello University College London<br />

Professor Mark Maslin University College London<br />

Dr Angela Wilkinson University of Oxford<br />

36 Acknowledgements<br />

GSK Study Sponsors<br />

Andrew Witty, Chief Executive Officer<br />

Duncan Learmouth, Senior Vice-President<br />

Developing Countries <strong>and</strong> Market Access<br />

Accenture Study Sponsor<br />

Peter Lacy, Managing Director, Accenture<br />

Sustainability Services Europe, Africa <strong>and</strong><br />

Latin America<br />

Smith School of Enterprise <strong>and</strong> <strong>the</strong><br />

Environment Study Sponsor<br />

Professor Sir David King, Director


Appendix 1<br />

Approach for quantifying <strong>the</strong> economic benefit of addressing <strong>the</strong> health impacts of climate change<br />

Background<br />

Economic analysis for this paper focuses on <strong>the</strong> climate<br />

change related additional incidents of malaria, diarrhoeal<br />

diseases, <strong>and</strong> stunting <strong>and</strong> wasting (malnutrition) in<br />

<strong>the</strong> following three WHO-classified regions: “Afr-D”<br />

(predominantly West Africa), “Afr-E” (predominantly<br />

South <strong>and</strong> East Africa) <strong>and</strong> “Sear-D” (predominantly<br />

South-East Asia).<br />

The analysis examines benefits across three climate<br />

change scenarios based on those used by <strong>the</strong> WHO in<br />

<strong>the</strong>ir Global Burden of Disease Study (2003):<br />

1. S550 – emissions reductions stabilise CO2 at 550 ppm<br />

CO2 equivalent in 2170.<br />

2. S750 – emissions reductions stabilise CO2 at 750 parts<br />

per million (ppm) in 2210<br />

3. Unmitigated Emissions (UE) – no action is taken to<br />

stabilise greenhouse gas emissions<br />

Objectives were to assess lost economic output <strong>and</strong><br />

derive estimates of net benefit in managing <strong>the</strong> three<br />

climate change related diseases.<br />

Method<br />

Benefits – Estimates of <strong>the</strong> additional climate change<br />

related incidence of disease in 2030 99 are used to<br />

generate disability-adjusted life years. This is combined<br />

with output per capita to determine total annual benefit<br />

gained from managing <strong>the</strong> diseases.<br />

Costs – Marginal cost of intervention per case is<br />

based on existing treatment costs for all cases of<br />

<strong>the</strong>se diseases adjusted for number of cases where<br />

intervention takes place.<br />

Net Benefit – Costs <strong>and</strong> benefits are spread from<br />

2010 to 2030, so both are discounted to Net Present<br />

Value (NPV) using a rate of 3.5 per cent. This discount<br />

rate is consistent with <strong>the</strong> UK Treasury’s Green Book<br />

recommendation for policy appraisal.<br />

Source: This analysis was carried out by <strong>the</strong> economics team<br />

at <strong>the</strong> Accenture Institute for High Performance: Mark Purdy,<br />

A<strong>the</strong>na Peppes, <strong>and</strong> Mat<strong>the</strong>w Robinson<br />

Figure A.1: Factors used to derive net benefit<br />

Net benefit<br />

Economic<br />

benefits<br />

Cost of<br />

intervention<br />

DALYs saved<br />

Output per<br />

life year<br />

Cost per<br />

incident<br />

Incidents that<br />

receive intervention<br />

Findings<br />

<strong>Climate</strong> <strong>Change</strong> <strong>and</strong> <strong>Health</strong>: <strong>Framing</strong> <strong>the</strong> Issue<br />

S550<br />

NPV (US$ bn, PPP)<br />

S750 UE<br />

Afr-D 6.41 7.52 11.02<br />

Afr-E 11.44 14.56 21.39<br />

Sear-D 15.13 20.51 21.11<br />

Total 32.97 42.58 53.52<br />

NPV (% of GDP, 2008)<br />

S550 S750 UE<br />

Afr-D 0.7 0.8 1.1<br />

Afr-E 1.3 1.6 2.4<br />

Sear-D 0.4 0.6 0.6<br />

Total 0.6 0.8 1.0<br />

Success of<br />

intervention factor<br />

Recurrence<br />

factor<br />

<strong>Climate</strong> change<br />

related DALYs<br />

Output per<br />

capita<br />

Output per capita<br />

growth rate<br />

Incidents that<br />

receive intervention<br />

<strong>Climate</strong> change<br />

related incidents<br />

Ratio of incidents<br />

to DALYs<br />

Appendix 1<br />

37


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EWEs will increase.<br />

38 Endnotes<br />

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Endnotes<br />

39

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