TEXANOL CAS N°: 25265-77-4
TEXANOL CAS N°: 25265-77-4
TEXANOL CAS N°: 25265-77-4
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102<br />
Irritation<br />
Study<br />
End Point : IRRITATION<br />
Chemical Name : Texanol<br />
<strong>CAS</strong> Number : <strong>25265</strong>-<strong>77</strong>-4<br />
Study type : LAB<br />
Test Subject<br />
Organism Medium Specification Route Lifestage Sex Number exposed Number controls<br />
GPIG<br />
SKN<br />
Species/strain/system : Hartley guinea pigs<br />
Test Substance<br />
Purity Grade : 99%<br />
Test Method and Conditions<br />
Test method :<br />
description<br />
Exposure<br />
Eastman Kodak Company, Health and Environment Laboratories Protocol;<br />
GLP: yes<br />
Exposure Type : SHORT<br />
Exposure Period : 9 d<br />
Dose / Concentration : 0.5 mL/ ANIMAL<br />
Exposure comments : A group of 5 animals were repeatedly administered 0.5 mL of the test chemical<br />
topically to the clipped skin of the back for a total of nine doses over an elevenday<br />
period. Both primary irritation and exacerbation of effects were measured.<br />
Test Results<br />
Affected in<br />
Organ Effect Rev. OnSet Sex Exposed - Controls<br />
--------- ----------- ------- ------------------- ------- -----------------------------<br />
- NEF<br />
SKIN<br />
IRRIT<br />
No irritation or exacerbation was observed at the site of application in any of the 5 treated guinea pigs during<br />
the first week of dosing. During the second week, slight, transient irritation was observed in three of five<br />
animals.<br />
References<br />
Primary Reference : #URKOD*<br />
O'Donoghue, J. L. Eastman Kodak Company Reports, TX-84-35, (1984)<br />
Secondary Reference : !SIDSP*<br />
OECD/SIDS. Screening Information Data Set (SIDS) of OECD High<br />
Production Volume Chemicals Programme, (1994)<br />
IRPTC Data Profile
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