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Elastic Registration of 3D Deformable Objects

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Delta errors (%)<br />

Delta errors (%)<br />

Delta errors (%)<br />

60<br />

50<br />

40<br />

30<br />

20<br />

10<br />

0<br />

60<br />

50<br />

40<br />

30<br />

20<br />

10<br />

0<br />

60<br />

50<br />

40<br />

30<br />

20<br />

10<br />

0<br />

Proposed<br />

GMMREG 2.5<br />

Proposed<br />

GMMREG 2.5<br />

Proposed<br />

GMMREG 2.5<br />

20 40 60 80 100<br />

15%<br />

20 40 60 80 100<br />

22%<br />

20 40 60 80 100<br />

30%<br />

Fig. 3. Robustness test comparison with the best GMMREG set (r = 2.5).<br />

original 15% 22% 30%<br />

Fig. 4.<br />

Sample surface errors on a slice.<br />

the obtained alignments may not be accurate enough for<br />

measuring changes.<br />

Our algorithm has been successfully applied to align <strong>3D</strong><br />

lung CT scans. The polynomial model proved to be a good approximation<br />

<strong>of</strong> the underlying physical deformation. Promising<br />

results were obtained on the available 8 image pairs with<br />

a median δ error <strong>of</strong> 8.41% (the mean and standard deviation<br />

were 7.99% and 3.03%, respectively). Some <strong>of</strong> these results<br />

are presented in Fig. 5, where we also show the achieved<br />

alignment on grayscale slices <strong>of</strong> the original lung CT images.<br />

For these slices, the original and transformed images were<br />

combined as an 8 × 8 checkerboard pattern.<br />

V. CONCLUSIONS<br />

We have proposed a novel elastic registration method which<br />

works without established correspondences. The basic idea<br />

is to set-up a system <strong>of</strong> non-linear equations whose solution<br />

directly provides the parameters <strong>of</strong> the aligning transformation.<br />

Herein, we considered a polynomial deformation model, but<br />

other diffeomorphism can also be used by approximating it<br />

via a Taylor expansion. The computational complexity has<br />

been analyzed for two alternative forms <strong>of</strong> the equations and<br />

optimal choice between these computational schemes has also<br />

been discussed. The efficiency and robustness <strong>of</strong> the proposed<br />

approach have been demonstrated on a large synthetic dataset.<br />

Our method compares favorably to two recent <strong>3D</strong> matching<br />

algorithms [1], [9]. Finally, the algorithm achieved promising<br />

results in aligning lung CT images.<br />

ACKNOWLEDGMENT<br />

This research was partially supported by the grant<br />

CNK80370 <strong>of</strong> the National Innovation Office (NIH) & the<br />

Hungarian Scientific Research Fund (OTKA); the European<br />

Union and co-financed by the European Regional Development<br />

Fund within the project TÁMOP-4.2.1/B-09/1/KONV-<br />

2010-0005. Lung images provided by Mediso Ltd., Budapest,<br />

Hungary.<br />

REFERENCES<br />

[1] B. Jian and B. C. Vemuri, “Robust point set registration using Gaussian<br />

mixture models,” IEEE Transactions on Pattern Analysis and Machine<br />

Intelligence, vol. 33, no. 8, pp. 1633–1645, Aug. 2011. [Online].<br />

Available: http://gmmreg.googlecode.com<br />

[2] C. Papazov and D. Burschka, “<strong>Deformable</strong> <strong>3D</strong> shape registration based<br />

on local similarity transforms,” Computer Graphics Forum, vol. 30,<br />

no. 5, pp. 1493–1502, Aug. 2011.<br />

[3] R. Sagawa, K. Akasaka, Y. Yagi, H. Hamer, and L. Van Gool, “<strong>Elastic</strong><br />

convolved ICP for the registration <strong>of</strong> deformable objects,” in Proceedings<br />

<strong>of</strong> International Conference on Computer Vision, IEEE. Kyoto,<br />

Japan: IEEE, Oct. 2009, pp. 1558–1565.<br />

[4] F. Michel, M. M. Bronstein, A. M. Bronstein, and N. Paragios, “Boosted<br />

metric learning for <strong>3D</strong> multi-modal deformable registration,” in Proceedings<br />

<strong>of</strong> International Symposium on Biomedical Imaging: From Nano to<br />

Macro, IEEE. Chicago, Illinois, USA: IEEE, Mar. 2011, pp. 1209–<br />

1214.<br />

[5] M. Holden, “A review <strong>of</strong> geometric transformations for nonrigid body<br />

registration,” IEEE Transactions on Medical Imaging, vol. 27, no. 1, pp.<br />

111–128, 2008.<br />

[6] F. L. Bookstein, “Principal warps: Thin-Plate Splines and the Decomposition<br />

<strong>of</strong> deformations,” IEEE Transactions on Pattern Analysis and<br />

Machine Intelligence, vol. 11, no. 6, pp. 567–585, 1989.

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