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JURNALUL PEDIATRULUI – Year XV, X<br />

, Vol. XV, Nr. 59-60<br />

60, , july<br />

j<br />

uly-december 2012<br />

ECHOGRAPHIC FOLLOW-UP OF REFLUX STATUS IN A<br />

CHILD WITH NEUROGENIC BLADDER AND<br />

INTERMITTENT VESICAL CATHETERIZATION<br />

Camelia Daescu 1,2 , Adela Chirita Emandi 1,2 , C Popoiu 1,2 ,<br />

A Craciun 1,2 , Andreea Militaru 1,2 , Oana Belei 1,2<br />

Abstract<br />

Objectives: We highlight the role of echography <strong>in</strong> the<br />

follow-up of an 8 year old girl with neurogenic bladder,<br />

right megaureter due to reflux; left obstructive megaureter,<br />

and impaired renal function.<br />

Methods: The patient came quarterly to follow-up, to<br />

evaluate renal function and possible <strong>in</strong>fections, while the<br />

hydronephrosis was evaluated by echography. She had<br />

<strong>in</strong>termittent vesical catheterization and antibiotic<br />

prophylaxis.<br />

Results: The girl was diagnosed at 3 months of age<br />

with <strong>co</strong>mplex renal malformation, one month later she<br />

underwent bilateral cutaneous ureterostomy. Ureteral<br />

reimplantation surgery was performed at the age of 1 year<br />

and 6 months. At age 6, abdom<strong>in</strong>al echography revealed<br />

bilateral hidronephrosis grade IV, which was susta<strong>in</strong>ed by<br />

uroMRI and stage 2 renal failure shown by renal function<br />

tests. Intermittent vesical catheterization 4 times/day and<br />

antibiotic prophylaxis were <strong>in</strong>itiated. The echographic<br />

follow-up reported that the reflux rema<strong>in</strong>ed mostly<br />

unchanged: left kidney had hydronephosis grade III, and the<br />

right kidney presented hydronephosis grade III/IV.<br />

Nevertheless the parenchymatous <strong>in</strong>dex <strong>in</strong>creased, which<br />

<strong>co</strong>rrelates with the improved renal function, from stage 2<br />

renal failure (moderate reduction <strong>in</strong> glomerular filtration<br />

rate=58mL/m<strong>in</strong>/1.73m2) to normal glomerular filtration<br />

rate. The blood urea nitrogen and creat<strong>in</strong><strong>in</strong>e levels slightly<br />

decreased. The ur<strong>in</strong>ary tract <strong>in</strong>fection rate rema<strong>in</strong>ed low.<br />

Conclusions: Long-term <strong>in</strong>termittent catheterization as<br />

method of treatment and prevention is associated with stable<br />

reflux status, renal function, and <strong>in</strong>fection rate, which <strong>in</strong> the<br />

end result <strong>in</strong> better quality of life for the patient.<br />

Echographic method of follow-up is reliable for medical<br />

exam<strong>in</strong>ations s<strong>in</strong>ce it is <strong>in</strong>formative, harmless and<br />

e<strong>co</strong>nomical.<br />

Key words: Echographic follow-up; child; <strong>in</strong>termittent<br />

vesical catheterization<br />

Background<br />

The ur<strong>in</strong>ary <strong>co</strong>mplications of patients with a<br />

neuropathic bladder <strong>co</strong>nsist of <strong>in</strong><strong>co</strong>nt<strong>in</strong>ence, <strong>in</strong>ability to<br />

empty the bladder, ur<strong>in</strong>ary <strong>in</strong>fection, and deterioration of the<br />

upper ur<strong>in</strong>ary tract. Intermittent self-catheterization (ISC) or<br />

carer/nurse-assisted cl<strong>in</strong>ically clean <strong>in</strong>termittent<br />

catheterization (CIC) has developed over the past 30 years<br />

as a means of treat<strong>in</strong>g patients with bladder-empty<strong>in</strong>g<br />

problems. It is now re<strong>co</strong>gnized as one of the safest methods<br />

of manag<strong>in</strong>g patients, especially those with neurogenic<br />

bladder disorders (1). CIC has been demonstrated to reduce<br />

<strong>in</strong>fection hazards and greatly improve the lives of many<br />

patients with micturition disorders. In 1972, Lapides et al<br />

(2) reported the successful treatment of neuropathic bladders<br />

with CIC and s<strong>in</strong>ce then CIC has be<strong>co</strong>me widely accepted as<br />

the ma<strong>in</strong> therapeutic management for patients with such<br />

bladders. CIC can be undertaken by health professionals <strong>in</strong> a<br />

variety of cl<strong>in</strong>ical sett<strong>in</strong>gs for a range of cl<strong>in</strong>ical <strong>in</strong>dications,<br />

and <strong>in</strong>creas<strong>in</strong>gly by patients themselves who use it as a<br />

long-term bladder management technique. The relative<br />

simplicity of the technique <strong>co</strong>mes with the potential for<br />

health professionals to underestimate the skills required<br />

when <strong>co</strong>nsider<strong>in</strong>g a regimen of <strong>in</strong>termittent catheterisation<br />

and, perhaps more importantly, to underestimate the impact<br />

it may have on <strong>in</strong>dividual patients (3). Adequate bladder<br />

empty<strong>in</strong>g can be achieved by CIC, but ur<strong>in</strong>ary <strong>in</strong><strong>co</strong>nt<strong>in</strong>ence<br />

may persist <strong>in</strong> the presence of detrusor hyperreflexia and/or<br />

low <strong>co</strong>mpliance bladder.<br />

Objectives<br />

To highlight the role of echography <strong>in</strong> the follow-up of<br />

an 8 year old girl with neurogenic bladder, right megaureter<br />

due to reflux; left obstructive megaureter, and impaired<br />

renal function.<br />

Case report<br />

History<br />

We present an 8 years old girl that we have <strong>in</strong><br />

management, <strong>in</strong> the Nephrology department of Emergency<br />

Hospital for Children “Louis Turcanu” <strong>in</strong> Timisoara. The<br />

child is the first born of healthy non-<strong>co</strong>nsangu<strong>in</strong>eous<br />

parents. There was no family history of similar symptoms.<br />

1 University of Medic<strong>in</strong>e and Pharmacy “Victor Babes” Timisoara<br />

2 Emergency Hospital for Children “Louis Turcanu” Timisoara<br />

E-mail: camidaescu@yahoo.<strong>co</strong>m, adela.chirita@yahoo.<strong>co</strong>m, mcpopoiu@yahoo.<strong>co</strong>m, ad_craciun@yahoo.<strong>co</strong>.uk,<br />

andreamilitaru@yahoo.<strong>co</strong>m, oana22_99@yahoo.<strong>co</strong>m<br />

14

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