Up to 50% of continuous flow oxygen therapy patients ... - Inogen One

Inogen has completed and published
more clinical data surrounding the
Inogen One than any other available
oxygen therapy product.
Inogen Specific Research
1. Stegmaier JP. Chatburn RL, Lewarski JS. “Determination of an Appropriate Nocturnal
Setting for a Portable Oxygen Concentrator with Pulsed-Dosed Delivery.” Abstract.
Respir Care November 2006;51(11): 1305.
Summary: The purpose of this study was to determine if a single titration of oxygen
using a POC during ambulation/exercise would provide an appropriate setting for
nocturnal use. The results suggested that an oxygen setting selection based on
daytime ADL/ambulation appears to produce effective nocturnal oxygen therapy
as evidenced by a mean sleeping SpO 2 of 92% and no clinically significant
desaturation.
2. Chatburn, R, Lewarski J, McCoy R. “Nocturnal oxygenation using a pulsed dose
oxygen conserving device compared to continuous flow oxygen.”
Respir Care March 2006;51(3): 252-256
Summary: The study compared nocturnal oxygenation with continuous flow
versus the Inogen One among a group of established LTOT users with chronic
lung disease. The results demonstrate that when appropriately titrated, the
Inogen One is essentially clinically equivalent to continuous flow oxygen.
The study also suggests that daytime pulse dose titrations may be effective
in determining nocturnal oxygenation.
3. Case, R, Hausmann R. “Use of a portable oxygen concentrator with a fixed minute
volume oxygen conserving device to deliver oxygen to exercising pulmonary
rehabilitation patients.” Abstract.
Respir Care November 2005;50(11):1510.
Summary: The study concluded that the Inogen One was as clinically effective as
continuous flow oxygen at maintaining target SpO 2 levels in high flow (4-5 lpm)
oxygen users during intense exercise.
4. McCoy, R, Lewarski, J. “A test for clinical equivalency: A portable concentrator with
integrated oxygen-conserving compared to continuous flow oxygen during
nocturnal use.” Abstract.
Respir Care November 2005; 51 (11):
Summary: This study demonstrated the Inogen One TM POC was able to deliver
adequate nocturnal oxygen therapy as evidenced by continuous SpO 2 monitoring
in 9 of 10 (90%) of patients studied. The resting daytime oxygen titration and the
resultant SpO 2 appears to be reasonably effective method for determining an
appropriate nocturnal oxygen setting.
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