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Cytoplasmic filaments - Investigative Ophthalmology & Visual Science

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1084 Gipson Invest. Ophthalmol. Vistial Sci.<br />

December 1977<br />

biologists are just beginning to sort out the<br />

functions of these filamentous structures<br />

within cells. Investigations of the role they<br />

may play in disease processes have only<br />

just begun. We are rather ignorant of disease<br />

at the cell organelle level; a sick organelle<br />

may be the very basis for a sick<br />

organ. Investigating the cell biology of filament<br />

systems of eye tissues may prove to be<br />

a fruitful avenue of research on normal and<br />

abnormal function of cells of the eye.<br />

Ilene K. Gipson<br />

Department of <strong>Ophthalmology</strong><br />

University of Oregon Health<br />

<strong>Science</strong>s Center<br />

Portland, Oregon<br />

REFERENCES<br />

1. Pollard, T., and Weihing, R.: Actin and<br />

myosin and cell movement, CRC Crit. Rev.<br />

Biochem. 2:1, 1974.<br />

2. Goldman, R., Pollard, T., and Rosenbaum,<br />

J.: Cell Motility, Books A, B, & C, Cold<br />

Spring Harbor Conferences on Cell Proliferation,<br />

vol. 3, 1976, Cold Spring Harbor Laboratory.<br />

3. Ishikawa, H., Bischoff, R., and Holtzer, H.:<br />

Formation of arrowhead complexes with<br />

heavy meromyosin in a variety of cell types,<br />

J. Cell Biol. 43:312, 1969.<br />

4. Lazarides, E., and Weber, K.: Actin antibody:<br />

the specific visualization of actin <strong>filaments</strong> in<br />

non-muscle cells, Proc. Natl. Acad. Sci.<br />

U.S.A. 71:2268, 1974.<br />

5. Sanger, J. W.: Intracellular localization of<br />

actin with fluorescently labeled heavy meromyosin,<br />

Cell Tissue Res. 161:431, 1975.<br />

6. Weber, K., and Groeschel-Stewart, U.: Antibody<br />

to myosin: the specific visualization of<br />

myosin-containing <strong>filaments</strong> in nonmuscle<br />

cells, Proc. Natl. Acad. Sci. U.S.A. 71:4561,<br />

1974.<br />

7. Gipson, I., and Anderson, R.: Actin <strong>filaments</strong><br />

in normal and migrating corneal epithelial<br />

cells, INVEST. OPHTHALMOL. VISUAL SCI. 16:<br />

161, 1977.<br />

8. Bumside, B., and Laties, A.: Actin <strong>filaments</strong><br />

in apical projections of the primate pigmented<br />

epithelial cell, INVEST. OPHTHALMOL. 15:570,<br />

1976.<br />

9. Nicolson, G., Smith, J., and Poste, G.: Effects<br />

of local anesthetics on cell morphology and<br />

membrane-associated cytoskeletal organization<br />

in BALB/3T3 cells, J. Cell Biol. 68:395,<br />

1976.<br />

10. Burns, R., Foerster, R., Laibson, P. R., and<br />

Gipson, I. K.: Chronic toxicity of local anesthetics<br />

on the cornea. In Leopold, I. H., and<br />

Burns, R. P., editors: Symposium on Ocular<br />

Therapy, vol. 10, New York, 1977, John<br />

Wiley & Sons, Inc.<br />

11. Lonchampt, M., Laurent, M., Courtois, Y.,<br />

Trenchev, P., and Hughes, R.: Microtubules<br />

and micro<strong>filaments</strong> of bovine lens epithelial<br />

cells: electron microscopy and immunofluorescence<br />

staining with specific antibodies, Exp.<br />

Eye Res. 23:505, 1976.<br />

12. Kaufman, P., and Barany, E.: Cytochalasin<br />

B reversibly increases outflow facility in the<br />

eye of the cynomolgus monkey, INVEST. OPH-<br />

THALMOL. VISUAL SCI. 16:47, 1977.<br />

13. Rathke, D., Schmid, E., and Franke, W.: The<br />

action of the cytochalasins at the subcellular<br />

level, Cytobiologia 10:366, 1975.<br />

14. Kapelovich, L., Conlon, S., and Pollack, R.:<br />

Defective organization of actin in cultured<br />

skin fibroblasts from patients with inherited<br />

adenocarcinoma, Proc. Natl. Acad. Sci. U.S.A.<br />

74:3019, 1977.<br />

15. Shohet, S., and Layzer, R.: The "muscle"<br />

of the red cell, N. Engl. J. Med. 294:221,<br />

1976.<br />

16. Steinert, P., and Idler, W.: Self-assembly of<br />

bovine epidermal keratin <strong>filaments</strong> in vitro, J.<br />

Mol. Biol. 108:547, 1976.<br />

17. Snyder, J., and Mclntosh, J.: Biochemistry<br />

and physiology of microtubules, Annu. Rev.<br />

Biochem. 45:699, 1976.<br />

18. Feeney, L., and Mixon, R.: An in vitro<br />

model of phagocytosis in bovine and human<br />

retinal pigment epithelium, Exp. Eye Res. 22:<br />

533, 1976.<br />

19. Eliasson, R., Mossberg, B., Camner, P., and<br />

Afzelius, B.: The immotile-cilia syndrome, N.<br />

Engl. J. Med. 297:1, 1977.<br />

20. Oliver, J.: Impaired microtubule function correctable<br />

by cyclic GMP and cholinergic<br />

agonists in the Chediak-Higashi syndrome,<br />

Am. J. Pathol. 85:395, 1976.

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