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9th Joint Meeting ISICR-ICS Cytokines & Interferons: From the ...

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WWW<br />

bioDBnet<br />

http://biodbnet.abcc.ncifcrf.gov/<br />

biological DataBase network is an application integrating a<br />

vast number of biological databases including Gene, UniProt,<br />

Ensembl, GO, Affy, RefSeq etc. The databases are created<br />

by downloading data from various public resources. They are<br />

formatted and maintained in a relational structure at <strong>the</strong><br />

Advanced Biomedical Computing Center.<br />

In <strong>the</strong> current release of bioDBnet <strong>the</strong>re are 179 distinct<br />

nodes and 626 edges. Brief notes on what bioDBnet<br />

currently offers<br />

db2db handles all <strong>the</strong> conversions from one database<br />

identifier to ano<strong>the</strong>r.<br />

dbWalk lets you walk through your own bioDBnet path.<br />

dbReport reports every possible information that it can get for<br />

a particular identifier.<br />

dbFind finds <strong>the</strong> type of identifiers and converts all into a<br />

chosen database identifier type<br />

bioDBnet also offers supporting analysis tools to <strong>the</strong> main<br />

functions<br />

orgTaxon for finding <strong>the</strong> taxon ID of an organism<br />

goTree to look at <strong>the</strong> parents of any go accession<br />

chrView for visualising data on chromosomes<br />

bioTaxon for finding genes, proteins or GO accessions based<br />

on search terms<br />

Bioinformatics Video Collection<br />

http://www.abnova.com/abvideo/<br />

Videos to help with techniques and instruments<br />

Clinical Trials Magnifier<br />

http://www.clinicalresearchclinic.com/<br />

The WHO Trials Registry database was downloaded on<br />

September 3, 2010 including a total of 118,331 trials.<br />

The vast majority (n=99,840, 84.4%) of <strong>the</strong> studies are clinical<br />

trials. About one-third of <strong>the</strong> trials registered are industrysponsored<br />

and two-thirds are non-industry sponsored trials.<br />

Twenty percent of all non-industry sponsored trials originate<br />

from trial registries in Australia & New Zealand, UK and<br />

Japan. In contrast, multi-national industry-sponsored trials<br />

are predominantly (96%) registered in <strong>the</strong> US trial registry.<br />

The US trial registry is recommended as <strong>the</strong> registry of<br />

choice for searching for industry-sponsored trials. The US<br />

trial registry also offers <strong>the</strong> user a much more powerful<br />

search engine than <strong>the</strong> WHO Trials Registry.<br />

Gene Trail<br />

http://genetrail.bioinf.uni-sb.de/index.php<br />

We present a comprehensive and efficient gene set analysis<br />

tool, called GeneTrail that offers a rich functionality and is<br />

easy to use. Our web-based application facilitates <strong>the</strong><br />

statistical evaluation of high-throughput genomic or<br />

proteomic data sets with respect to enrichment of functional<br />

categories. GeneTrail covers a wide variety of biological<br />

categories and pathways, among o<strong>the</strong>rs KEGG, TRANSPATH,<br />

TRANSFAC, and GO. Our web server provides two common<br />

statistical approaches, “Over-Representation Analysis” (ORA)<br />

comparing a reference set of genes to a test set, and “Gene<br />

Set Enrichment Analysis” (GSEA) scoring sorted lists of<br />

genes. Besides o<strong>the</strong>r newly developed features, GeneTrail’s<br />

statistics module includes a novel dynamic-programming<br />

algorithm that improves <strong>the</strong> p-value computation of GSEA<br />

methods considerably.<br />

iBioMagazine<br />

http://www.ibiomagazine.org/<br />

iBioMagazine offers a collection of short (

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