14th European Congress of Clinical Microbiology and Infectious ...

First Final Announcement Programme 

14 th European Congress of Clinical 

Microbiology and Infectious Diseases 

Prague /Czech Republic, May 1 – 4, 2004

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Table of Contents 

Overview Prague Congress Centre (PCC) __________________________________________ 2/3 

Important Addresses ________________________________________________________________________ 5 

Welcome Address ____________________________________________________________________________ 6 

ESCMID News from the President ______________________________________________________ 7 

Acknowledgements __________________________________________________________________________ 8 

Committees ________________________________________________________________________________ 9–12 

ESCMID Awards 2004 ________________________________________________________________ 15–17 

Scientific Programme Overview __________________________________________________ 18–21 

Introduction to the Scientific Programme __________________________________________ 23 

Instructions for Authors __________________________________________________________________ 24 

Business Meetings __________________________________________________________________________ 25 

Scientific Programme ________________________________________________________________ 27–64 

Saturday, May 1, 2004 __________________________________________________________________ 27/29 

Sunday, May 2, 2004 ____________________________________________________________________ 31–41 

Monday, May 3, 2004 __________________________________________________________________ 43–55 

Tuesday, May 4, 2004 __________________________________________________________________ 56–64 

Poster Sessions ________________________________________________________________________ 65–147 

Sunday, May 2, 2004 ____________________________________________________________________ 65–91 

Monday, May 3, 2004 ________________________________________________________________ 92–119 

Tuesday, May 4, 2004 ______________________________________________________________ 120–147 

List of Chairpersons ______________________________________________________________________ 148 

List of Authors ______________________________________________________________________ 149–169 

General Information ________________________________________________________________ 170–172 

Exhibition ______________________________________________________________________________ 173–175 

Social Events ________________________________________________________________________________ 176 

Daily Tours ____________________________________________________________________________ 177/178 

Future ECCMIDs ____________________________________________________________________________ 179 

Prague City Map ____________________________________________________________________ 180–181 

www.escmid.org/eccmid2004 

page 1

Overview Prague Congress Centre (PCC) 

Sunday, May 2 P 764–P 913 

Monday, May 3 P1252–P1400 

Tuesday, May 4 P1747–P1896 

Fourth Floor 

page 2 Final Programme 


Monday, May 3 P1087–P1251 


Third Floor 

Ground Floor

First Floor 

Overview Prague Congress Centre (PCC) 


Monday, May 3 P 914–P1086 


Second Floor 


page 3

Important Addresses 

During the Congress 14 th ECCMID Phone +420 261 177010 

Administrative Secretariat Fax +420 261 177011 

c/o Prague Congress E-mail info@akm.ch 

Centre (PCC) 

5 Kvetna 65 

CZ-140 21 Prague 4 

Czech Republic 

Congress President Prof. Jarmila Jelinkova Phone +420 271 019 294 

Institute for Postgraduate Fax +420 271 019 269 

Medical Education E-mail jelinkova@ipvz.cz 

Ruská 85 



Administrative Secretariat 14 th ECCMID Phone +41 61 686 77 11 

c/o AKM Congress Service Fax +41 61 686 77 88 

P.O. Box E-mail info@akm.ch 

CH-4005 Basel 

Switzerland 

Scientific Secretariat 14 th ECCMID Phone +41 61 686 77 99 

c/o ESCMID Executive Office Fax +41 61 686 77 98 

P.O. Box E-mail info@escmid.org 

CH-4005 Basel 


Accommodation AKM Travel AG Phone +41 61 690 94 11 

Messeplatz 10 Fax +41 61 690 94 14 

P.O. Box E-mail eccmid@akmtravel.ch 

CH-4016 Basel 


Local Agency CZECH-IN Phone +420 261 174 301 

Prague Congress Centre Fax +420 261 174 307 

5 Kvetna 65 E-mail eccmid@czech-in.cz 





page 5

Welcome Address 

Dear Colleagues, Dear Participants, Dear Friends 

It gives me great pleasure to welcome you to this important event organised by the European Society of 

Clinical Microbiology and Infectious Diseases here in Prague. It takes place for the first time in this part 

of Europe, in a country with a long history and rich culture. The Charles University was founded in Prague 

in 1348 and represents the oldest University in Central Europe. 

It is a great honour to welcome you on behalf of the Organising- and the National Committee to the 

14 th ECCMID. We are particularly honoured that the ESCMID has decided to hold its major scientific meeting 

here. The annual European Congress of Clinical Microbiology and Infectious Diseases is proposing a 

challenging programme covering all aspects of human infections. 

This years meeting will be attended by a very large number of participants from all over Europe and 

other parts of the world. Stimulating presentations of the latest research findings in laboratory and clinical 

diagnostic, therapy and prevention of infectious diseases will be addressed in a truly interdisciplinary 

perspective. 

The ECCMID provides a unique opportunity for infection specialists to exchange knowledge and share 

experience. Moreover, it offers the young scientists and practitioners a direct exposure to the critical exam 

ination of their data. The scientific and organising committees together created an advanced and multiform 

scientific and educational programme, as outlined in the Address of Prof. Marc Struelens, President of the 

ESCMID. 

I hope that you will remember for a long time the fascinating experience of the spring atmosphere in the 

city of Prague. 

I wish all of you a pleasant stay and an enriching meeting. 

Prof. J. Jelinkova 

President 14 th ECCMID 

page 6 Final Programme

ESCMID – News from the President 

Dear Colleagues and Members of European Society of Clinical Microbiology and Infectious Diseases 

Welcome to Prague on the occasion of the 14th European Congress of Clinical Microbiology and Infectious Diseases 

(ECCMID). The ECCMID is one of the largest international meetings in its field. It focuses on the implications of latest 

research findings for the advancement of laboratory, clinical and public health practice in diagnosis, therapy and pre - 

vention of infection. This year’s superb Scientific Programme has again been developed by the ECCMID Programme 

Committee under the remarkable leadership of Prof. Patrick Francioli, in association with Czech colleagues of the 

Organising Committee. We are most grateful to them and to Prof. Jarmila Jelinkova, President of the Congress, as 

well as to all the clinicians and scientists who are contributing to this programme. 

This year’s ECCMID opens on the historical day when the Czech Republic and nine other countries of Eastern and 

Southern regions of the continent are joining the enlarged European Union. Science and Medicine have long been 

leading the way to peaceful collaboration across national borders. In the field of infectious diseases, the need for 

international co-operation has never been greater. Therefore, the broadest participation of colleagues from all parts 

of Europe and beyond is essential to address the challenges that we are facing. To this end, a record number of 

attendance grants and support from local societies have been arranged to allow young scientists and clinicians to 

present their data at the 14th ECCMID. 

The scientific and organising committees have developed a truly cutting-edge programme that offers a choice of a 

hundred oral sessions, including keynote lectures by outstanding scientists, state-of-the-art symposia, interactive 

sessions, meet-the expert tutorials, reports of ESCMID Study Groups and integrated industrial symposia. Thanks to 

an all-time record in quantity and quality of abstracts submitted, selected new data will be shared in 200 oral and 

1500 poster presentations. As last year, guided poster walks will discuss new findings of particular interest. 

ESCMID recognises the leading contribution that European scientists have given to medical microbiology and the 

study of infectious diseases. It gives me special pleasure to invite you to attend the lecture by Prof. Jean-Paul Butzler 

(Belgium), who is this year’s recipient of the ESCMID Award for Excellence in Clinical Microbiology and Infectious 

Diseases, on Sunday May 2 opening session. I also encourage you to attend the presentations by the recipients of 

the Young Investigator Awards, Dr. Marc Lecuit (France) and Dr. Arianna Loregian (Italy) on Monday May 3. 

The annual ECCMID also offers you the opportunity to progress co-operative projects and education initiatives 

through the annual business meetings of the thematic ESCMID Study Groups and EUCAST, the EU Committee on 

Antimicrobial Susceptibility Testing. Do not hesitate to join any of these meetings if you are interested in becoming 

a member of one of these groups. I also invite you to stop by the ESCMID booth and the nearby European Network 

Corner. In this area suitable for informal meetings, information material will be available about ongoing ESCMID 

Study Group activities, European projects supported by ESCMID such as EARSS and ESAC, and European Commission 

programmes in biomedical science and public health. 

Over the last years, our society has matured and expanded its range of activities. It should respond to the evolving 

needs of its membership by adapting its organisational modalities. The European Council Meeting will be holding 

its meeting on Saturday May 1. I welcome all elected delegates and representatives of specialist societies to attend 

this Council meeting where a new affiliation scheme will be proposed as the basis for a renewed Council with the 

aim of strengthening our partnership with National Societies of Microbiology and Infectious Diseases. The plan for a 

single European Congress in the infection disciplines in co-operation with other international organisations will also 

be presented. The ESCMID General Assembly of Members will be held during the lunch break on Sunday May 2. 

I encourage all members to attend this important meeting. In addition to the Executive Committee’s report of 

activities, revisions of the Society’s Statutes meant to foster democratic rule will be presented and submitted for 

approval. 

I look forward to meeting many of you during the next few days. I especially hope to meet you at the Opening Ceremony 

on Saturday May 1. Among eminent personalities, Mr. Georgios Gouvras from the Directorate General Health 

and Consumer Protection of the European Commission will be addressing delegates on the EU Health Programme 

and the perspective of establishing the European Center for Disease Prevention and Control. The ceremony will 

conclude with a performance by the Prague Black Light Theatre. A welcome cocktail and entertainment will follow. 

I wish that the 14th ECCMID offers you the scientific excellence, inter-disciplinary dimension and social experience 

that you expect from a world class congress while allowing you to enjoy the unique atmosphere of the beautiful city 

of Prague. Thank you for attending ECCMID. I hope that you will return home with up-to-date knowledge, new ideas, 

and enthusiasm about translating these into your practice. 

Prof. Marc Struelens 

President of ESCMID 


page 7

Acknowledgements 

The Organising Committee expresses its 

thanks and appreciation to those who are 

generously contributing to the success of 

the 14 th European Congress of Clinical 

Microbiology and Infectious Diseases. 

Platinum Medal Sponsors Merck & Co., Inc. 

Pfizer Inc. 

Gold Medal Sponsors AstraZeneca 

Wyeth Pharmaceuticals 

Silver Medal Sponsors Aventis Pharma S.A. 

BD Diagnostic Systems 

BioMérieux 

Chiron 

Fujisawa 

Gilead 

GlaxoSmithKline 

Pliva d.d. 

Vicuron Pharmaceuticals 

Other Sponsors Bayer Pharmaceutical Corporation 

ESCMID and the ECCMID Programme ISF International Sepsis Forum 

Committee are proud to acknowledge Future targets for therapeutic interventions 

the scientific input from the following in sepsis 

organisations in setting up joint symposia: (page 32) 


ASM American Society of Microbiology 

ICAAC Program Committee 

New technologies for microbiological diagnostics 

(page 44) 

IDSA Infectious Disease Society of America 

Diarrhoeal diseases 

(page 44) 

EORTC – IATG European Organisation for Research and 

Treatment of Cancer – International 

Antimicrobial Therapy Group 

Cancer and infection: a two-way road 

(page 57)

Committees 

Organising Committee 

Jarmila Jelinkova 

Prague, CZ 

Congress President 

Jiri Beran 

Hradec Kralove, CZ 

National Scientific Coordinator 

Patrick Francioli 

Lausanne, CH 

ECCMID Programme Director 

ESCMID Executive Committee 

M. Struelens, Brussels, B 

President 

C. Carbon, Paris, F 

Education Officer 

G. Cornaglia, Verona, I 

Secretary General 

R. Finch, Nottingham, UK 

Past President 

P. Francioli, Lausanne, CH 


Ex officio members 

N. Høiby, Copenhagen, DK 

President 15 th ECCMID 2005 

J. Jelinkova, Prague, CZ 

President 14 th ECCMID 2004 

C.E. Nord, Stockholm, S 

Editor CMI Supplements 


Jan Galsky 

Melnik, CZ 

National Secretary 

Peter Schoch 

Basel, CH 

ESCMID Managing Director 

Marc Struelens 

Brussels, B 

ESCMID President 

E. Nagy, Szeged, H 

Professional Affairs Officer, Clinical Microbiology 

S.R. Norrby, Stockholm, S 

President-elect 

Professional Affairs Officer, Infectious Diseases 

A. Voss, Nijmegen, NL 

Treasurer 

J. Vila, Barcelona, E 

Scientific Affairs Officer 

K. Towner, Nottingham, UK 

CMI Editor-in-Chief 

P. Schoch, Basel, CH 

Managing Director 

page 9

Committees 

14 th ECCMID Programme Committee 

P. Francioli, Lausanne, CH 


M. Akova, Ankara, TR 

J. Beran, Hradec Kralove, CZ 

J. Bille, Lausanne, CH 

P. Chalupa, Brno, CZ 

G. Cornaglia, Verona, I 

D. Durack, North Carolina, USA 

J. Edwards, Macclesfield, UK 

N. Frimodt-Moller, Copenhagen, DK 

I. Gould, Aberdeen, UK 

National Committee 

V. Maresova, Prague 

J. Benes, Prague 

P. Chalupa, Brno 

V. Jindrak, Prague 

P. Kriz, Prague 

S. Plisek, Hradec Kralove 

ESCMID Education Committee 

C. Carbon, Paris, F 

ESCMID Education Officer 

M. Falagas, Athens, GR 

R. Filip, Iasi, RO 

I.M. Hoepelman, Utrecht, NL 


C. Hatz, Basel, CH 

M. Ieven, Edegem, B 

V. Jarlier, Paris, F 

J. Jelinkova, Prague, CZ 

G. Kahlmeter, Växjé, S 

S. Kalenic, Zagreb, CRO 

P. Kriz, Prague, CZ 

H. Nielsen, Aalborg, DK 

E. Rubinstein, Tel-Hashomer, IL 

M. Struelens, Brussels, B 

A. Vaheri, Helsinki, FIN 

A. Voss, Nijmegen, NL 

D. Prusova, Sternberk 

J. Scharfen, Trutnov 

M. Stankova, Prague 

P. Urbaskova, Prague 

M. Votava, Brno 

L. Martínez-Martínez, Seville, E 

L. Peixe, Porto, P 

G. Schmid, Geneva, CH 

A. Schwenk, London, UK 

G.M. Scott, London, UK 

G. Zanetti, Lausanne, CH

Committees 

ESCMID Study Groups Chairperson 

Nosocomial Infections A. Voss, Nijmegen, NL 

a.voss@mmb.umcn.nl 

Molecular Diagnostics M. Ieven, Edegem, B 

greet.ieven@uza.uia.ac.be 

Experimental Infections P. Moreillon, Lausanne, CH 

philippe.moreillon@imf.unil.ch 

Rickettsia, Coxiella, Ehrlichia and J.A. Oteo, Logrono, E 

Bartonella jaoteo@hgr.seris.es 

Epidemiological Markers A. van Belkum, Rotterdam, NL 

a.vanbelkum@erasmusmc.nl 

Antimicrobial Resistance Surveillance F. Baquero, Madrid, E 

baquero@bitmailer.net 

Antibiotic Policies I. Gould, Aberdeen, UK 

i.m.gould@abdn.ac.uk 

Clostridium difficile J. Brazier, Cardiff, UK 

brazier@cardiff.ac.uk 

Helicobacter T. Wadström, Lund, S 

Antimicrobial Resistance in 

wadstrom@mmb.lu.se 

C.E. Nord, Stockholm, S 

Anaerobic Bacteria carl.erik.nord@labmed.ki.se 

Fungal Infections D. Denning, Manchester, UK 

ddenning@man.ac.uk 

Toxoplasmosis B. Evengård, Stockholm, S 

birgitta.evengard@labmed.ki.se 

European Committee on G. Kahlmeter, Växjö, S 

Antimicrobial Susceptibility gunnar.kahlmeter@ltkronoberg.se 

Testing (EUCAST) 

ESCMID European Council – Elected Country Representatives 

F. Allerberger, Innsbruck Austria 

Y. Glupczynski, Yvoir Belgium 

S. Janjic, Sarajewo Bosnia-Herzegovina 

J. Skrlin, Zagreb Croatia 

V. Jindrak, Prague Czech Republic 

B. Bruun, Charlottenlund Denmark 

P. Huovinen, Turku Finland 

R. Leclercq, Caen France 

P. Shah, Frankfurt Germany 

E. Malamou-Ladas, Palea-P. Greece 

F. Rozgonyi, Budapest Hungary 

H. Humphreys, Dublin Ireland 

C. Block, Jerusalem Israel 

D. Marchetti, Bologna Italy 

A. Zilevica, Riga Latvia 

A. Ambrozaitis, Vilnius Lithuania 

P. Brouart, Luxembourg Luxembourg 

J. Meis, Nijmegen Netherlands 

S. Harthug, Bergen Norway 

D. Dzierzanowska, Warsaw Poland 

M. T. Marques, Lisboa Portugal 

I. Rebedea, Bucharest Romania 

A. A. Firsov, Moscow Russia 

M. Svabic-Vlahovic, Belgrade Serbia-Montenegro 

J. Kazar, Bratislava Slovak Republic 

S. Koren, Ljubljana Slovenia 

L. Martinez-Martinez, Seville Spain 

G. Kahlmeter, Växjö Sweden 

J. Bille, Lausanne Switzerland 

M. Akova, Ankara Turkey 

R. C. Read, Sheffield United Kingdom 


page 11

Committees 

ESCMID European Council – Representatives of Specialist Societies 

M. Alkan, Beersheva, IL Israeli Society of Infectious Diseases 

Ö. Ang, Istanbul, TR Turkish Society for Microbiology 

S. Breyer, Vienna, A Österreichische Gesellschaft für Chemotherapie 

O. Cars, Uppsala, S Scandinavian Society of Antimicrobial Chemotherapy 

M. Doganay, Kayseri, TR Hospital Infections Society of Turkey 

H. Eraksoy, Istanbul, TR Turkish Society of Clinical Microbiology and Infectious Diseases 

G. Falcone, Pisa, I Società Italiana di Microbiologia Medica, Odontoiatrica e Clinica 

J. Garcia-Rodriguez, Salamanca, E Spanish Society of Chemotherapy 

J. Germano Sousa, Lisbon, P Portuguese Society of Clinical Pathology 

H. Giamarellou, Athens, GR Hellenic Society of Chemotherapy 

F.D. Goebel, München, D Deutsche Gesellschaft für Infektiologie 

M. Gubina, Ljubljana, SLO Slovenian Society for Clinical Microbiology and Hospital Infection of SMC 

D. Haas, Lausanne, CH Swiss Society for Microbiology 

W. Halota, Bydgoszcz, PL Polish Society of Infectious Diseases Physicians and Epidemiologists 

J.O. Jarlov, Herlev, DK Danish Society of Clinical Microbiology 

J. Jelinkova, Prague, CZ Czech Society for Epidemiology and Microbiology 

T. Jeren, Zagreb, CRO Croatian Society of Infectious Diseases 

S. Kalenic, Zagreb, CRO Croatian Society of Medical Microbiology and Parasitology 

M.C. Kelsey, London, UK Association of Medical Microbiologists 

M. Koskela, Oulu, FIN Finlands Microbiologists 

J. Kosmidis, Athens, GR Hellenic Society for Infectious Diseases 

D. Kotulova, Bratislava, SK Society for Microbiology and Epidemiology of SMA 

P. Kujala, Oulu, FIN Finnish Society for the Study of Infectious Diseases 

P. Larsson, Göteborg, S Swedish Society of Medical Microbiology 

N.J. Legakis, Athens, GR Hellenic Society for Microbiology 

E. Ludwig, Budapest, H Hungarian Society for Chemotherapy 

A. Maeland, Oslo, N Norwegian Society of Infectious Diseases 

E. Magliano, Milan, I Associazione Microbiologi Clinici Italiani 

T. Mazzei, Florence, I Società Italiana di Chemioterapia 

M. McKendrick, Sheffield, UK British Infection Society 

F. MacKenzie, Aberdeen, UK Scottish Microbiology Association 

S. Moreno, Madrid, E Spanish Society of Infectious Diseases and Clinical Microbiology 

P.G. Murphy, Dublin, IR Irish Society of Clinical Microbiology 

I. Muzlovic, Ljubljana, SLO Slovenian Association of Infectious Diseases of SMC 

J. Nikoskelainen, Turku, FIN Finnish Society for Infectious Diseases 

A. Ortqvist, Stockholm, S Swedish Society of Infectious Diseases 

B.K. Pedersen, Copenhagen, DK Danish Society of Infectious Diseases 

G. Peters, Munster, D Deutsche Gesellschaft für Hygiene und Mikrobiologie 

H.E.T. Pichler, Vienna, A Österreichische Gesellschaft für Infektionskrankheiten 

R. Proenca, Lisbon, P Portuguese Society of Infectious Diseases 

H. Rautelin, Helsinki, FIN Finnish Society for Clinical Microbiolology 

L. Rokusz Budapest, H Hungarian Society of Infectiologists 

J. Schirm, Groningen, NL European Society for Clinical Virology 

R. Schoyen, Tonsberg, N Norwegian Society of Medical Microbiology 

P.M. Shah, Frankfurt, D Paul-Ehrlich-Gesellschaft für Chemotherapie 

P. Speelman, Amsterdam, NL Infectious Diseases Society of the Netherlands and Flanders 

G. Stanek, Vienna, A Österreichische Gesellschaft für Hygiene, Mikrobiologie und Präventivmedizin 

M. Stankova, Prague, CZ Czech Society for Infectious Diseases 

L. Stratchounski, Smolensk, RS IACMAC 

M.G. Täuber, Berne, CH Swiss Society for Infectious Diseases 

S. Ünal, Ankara, TR Infectious Diseases Society of Turkey 

L. Verbist, Leuven, B Belgian Society of Infectious Diseases and Clinical Microbiology 

H.A. Verbrugh, Rotterdam, NL Netherlands' Society for Medical Microbiology 

J.L. Vilde, Paris, F Société de Pathologie Infectieuse de Langue Française 

R. Wise, Birmingham, UK British Society for Antimicrobial Chemotherapy 


Treating infection right... First time 

Objectives 

The vision for the Academy for Infection Management 

is to gain wider acceptance of the concept of using 

appropriate antibiotics early in nosocomial infections, 

to improve outcomes by reducing mortality, morbidity 

and length of stay in hospital. 

The objectives set out for the Academy for Infection 

Management are to: 

www.infectionacademy.org 

Supported by an educational grant from AstraZeneca. 

AstraZeneca 

Anti-infectives Group, Alderley House, 

Alderley Park, Macclesfield, Cheshire, UK. 

7945/March 2004 

Academy for Infection Management 

Provide a global education resource for physicians 

involved in the treatment of nosocomial infections 

(ID physicians, surgeons, chest physicians, 

microbiologists) 

Share best clinical practice 

Share latest clinical and scientific data on 

nosocomial infection management with regard 

to improving patient outcomes.

Academy for Infection Management 

Visit our stand at the congress, or on our website at: 

www.infectionacademy.org 

The Academy for Infection Management have produced supportive educational 

materials, that are available free of charge at the above website. These include 

Slide Kits, Core references, Illustrative cases, Materials (Workmats) for 

training staff. All illustrate the following core principles of the Academy: 

Patient outcomes 

Select the most appropriate antibiotic 

depending on the patient, risk factors, 

suspected infection and resistance 

Antibiotic choice 

It is important to start with the appropriate 

empiric antibiotic first in nosocomial 

infections 

Administer antibiotics at the right dose 

for the appropriate duration 

If appropriate, change antibiotic dosage 

or therapy based on resistance and 

pathogen information 

Supported by an educational grant from AstraZeneca. 

AstraZeneca 

Anti-infectives Group, Alderley House, 

Alderley Park, Macclesfield, Cheshire, UK. 

7945/March 2004 

Resistance 

Recognise that prior antimicrobial 

administration is a risk factor for the 

presence of resistant pathogens 

Know the unit’s resistance profile and 

choose antibiotics accordingly 

Infection control 

Wash hands adequately and wear gloves 

appropriately 

Remove indwelling devices as soon as 

they are no longer indicated

ESCMID Awards 2004 

Award for Excellence in Clinical Microbiology and Infectious Diseases 

Jean Paul Butzler, born 1941 in Brussels, Belgium 

Professor of Clinical Microbiology and Epidemiology at the Free University of Brussels, 

in recognition of his outstanding contributions in research, teaching and international 

co-operation in the fight against infectious diseases related to poverty, in particular diarrhoeal 

diseases. Throughout his medical career he has translated the concerns about poverty and 

poor health care in the developing world into collaborative research programmes. He has 

been instrumental in establishing reference microbiology laboratories in some of the most 

deprived regions, notably in Central Africa. In addition, he has trained and promoted many 

foreign and Belgian students who are now among the new generation of opinion leaders in 

the infection disciplines. 

Research Interests 

Jean-Paul Butzler’s early research concentrated on the diagnosis and treatment of enteric 

diseases. In 1974 he was the first to show that “Related Vibrio”, now called Campylobacter 

jejuni/coli, was a frequent cause of acute human enteritis and that early administration of 

erythromycin significantly reduced the duration of both diarrhoea and faecal excretion in 

patients with severe campylobacter enteritis. In 1972, he started the laboratory of clinical 

microbiology at the hospital of malnourished children in Lwiro, Bukavu, Congo where he 

concentrated on the rapid diagnosis and treatment of septicaemia and the management 

of hospital infections. In 1980 the WHO appointed Jean-Paul Butzler Director of the WHO 

Collaborating Centre for Enteric Campylobacter. From 1985 to 1990 Jean-Paul Butzler 

focused his research on HIV infections in Rwanda. His teams at the St Peter’s University 

Hospital in Brussels and the Kigali Hospital, Rwanda, in conjunction with the Institute for 

Tropical Medicine in Antwerp, were the first to show that HIV could be heterosexually 

transmitted. Today Jean-Paul Butzler supervises a team of young medical doctors both at 

the hospital for malnourished children in Lwiro, Bukavu, Congo and at the St Peter’s 

University Hospital in Brussels. Their current research focus is on emerging potential 

enteric pathogens and infection control. 

Young Investigator Awards for Research in Clinical Microbiology and Infectious Diseases 

Arianna Loregian, born 1968 in Padua, Italy 

PhD, Assistant Professor of Microbiology and Clinical Microbiology, Medical School, 

University of Padua, Italy, in recognition of her innovative work on the molecular 

mechanisms, especially protein-protein interactions, involved in viral replication of 

herpes simplex virus, HIV and human cytomegalovirus. 


During the past few years, Arianna Loregian's research focused on the study of viral replication 

mechanisms and the characterisation of protein-protein interactions between viral and/or 

cellular proteins as new targets for antiviral chemotherapy. Some of these studies were 

aimed at characterising protein-protein interactions between herpesvirus enzyme subunits, 

for example HSV-1 ribonucleotide reductase and HSV-1, HCMV and EHV-1 DNA polymerase, 

and at identifying antiviral peptides and peptidomimetic compounds that mimic either face 

of the subunit interaction and therefore are able to disrupt the viral protein complexes. She 

has also characterised the interaction of HIV-1 Tat protein with cellular factors. These studies, 

which dissected some key protein-protein interactions involved in the assembly of transcription 

complexes at the HIV-1 LTR, could contribute to unravelling the puzzling mechanism of HIV-1 

replication and to suggest novel strategies for anti-HIV chemotherapy. 


page 15


Young Investigator Awards for Research in Clinical Microbiology and Infectious Diseases 

Marc Lecuit, born 1966 in Paris, France 

MD, Department of Infectious Diseases and Tropical Medicine, Necker University Hospital, 

and Pasteur Institute, Paris, France, in recognition of his outstanding contributions to our 

understanding of the molecular pathogenesis of Listeria monocytogenes infection based 

on laboratory investigations, animal models and human epidemiological studies. 


Marc Lecuit’s research is focused on the pathophysiology of human infectious diseases. 

As a clinician and a researcher, he is particularly interested in understanding the specific 

host and organ tropisms of microbial pathogens, and the mechanisms they deploy to breach 

physiological barriers such as the intestinal barrier, the blood-brain barrier and the materno - 

f etal barrier. His research has mainly focused on the Listeria model. He has investigated the 

molecular mechanism by which this bacterial species enters non-phagocytic cells, and 

discovered the species-specificity of Listeria monocytogenes. This led to the generation of a 

transgenic mouse model for human listeriosis. His current research focuses on the molecular 

mechanisms accounting for microbial central nervous and/or maternofetal tropisms. 

A complementary area of Marc Lecuit's interest is the putative infectious origin of orphan 

diseases. Recently, he has coordinated a study on the microbial origin of a rare form of 

intestinal lymphoma (IPSID) known to respond in its early stages to antibiotics. This led to 

the discovery of an association between this type of lymphoma and Campylobacter jejuni. 

The two Young Investigator Awards are sponsored by Pfizer Inc. 

ISF Award 2004 

Tom Sprong, born 1975 in s'Hertogenbosch, the Netherlands 

MD, University Medical Centre St Radboud Nijmegen, Department of General Medicine, 

in recognition of his excellent poster presented at 14 th ECCMID on the complement 

activation during meningococcal disease. His data demonstrate that the initial activation 

of the complement system during meningococcal infection is highly correlated with 

disease severity and that complement activation occurs via the alternative and lectin 

pathways, whereas classical pathway engagement develops only after 24 hours. 


Sepsis, complement, cytokines and cytokine receptors and Neisseria meningitis 

sponsored by the International Sepsis Forum 



ESCMID / FEMS Research Fellowship 

ESCMID and FEMS have agreed on a joint 

initiative to foster outstanding research in 

microbiology by young Europeans. Every year 

each organisation will select one individual 

among their recipients of research fellowships 

to receive an additional amount of EUR 1000 

from the other organisation. We are delighted 

to announce that the first combined ESCMID / 

FEMS fellowship goes in 2004 to Roy Sleator 

from Cork, Ireland. 

Roy Sleator, born 1975 

in Kerry, Ireland 

PhD, Department of 

Microbiology, BioSciences 

Institute, University College, 

Cork, Ireland 


In the post-genomic era, Roy Sleator’s research 

will focus on the relationships between the 

genome, the proteome, and most importantly, 

the functionality of whole organisms. 

The most important functionality attributes of 

Listeria monocytogenes lie in its ability to 

survive and grow in foods and cause disease 

in humans. Both attributes are predicated on 

the ability of the organism to sense and 

respond in an apposite manner to changes 

in its environment. One of the most efficient 

ways in which to convert a physical or 

biological signal into an appropriate biological 

response is to use two-component signal 

transduction systems (2-CS). The LisRK system 

is unique in that it is the first 2-CS identified 

in Listeria, which has a demonstrable role in 

the virulence of the organism, in addition 

to playing a role in its ability to respond to 

environments external to the host. His analysis 

of this system will provide valuable insights 

into the stress sensing capabilities of this 

important pathogen, and the role that such 

stress sensing plays in its virulence. 

ESCMID Research Fellowships 

Jean-Denis Doquier, 

born 1974 in Liège, Belgium 

PhD, Centre for Protein 

Engineering, University 

of Liège, Liège, Belgium 


Jean-Denis Docquier’s research interests 

mainly concern the β-lactamase-mediated 

resistance mechanisms to β-lactam antibiotics 

in Gram-negative bacteria, including the 

molecular and genetic characterisation of 

multiresistant isolates, and the biochemical 

characterization of new enzymes. His present 

work is particularly focused on the study of 

the emerging acquired metallo-β-lactamases 

of the IMP- and VIM-type, whose production 

confers to the host a broad resistance profile 

usually including carbapenems and classical 

�-lactamase inactivators. In this area, his 

studies also aim at understanding the genetic 

mechanisms involved in the horizontal 

dissemination of the blaIMP and blaVIM genes 

and the structure-function relationships of 

these important metallo-enzymes, for which 

no clinically useful inhibitor is currently 

available. 

Laurent Poirel, born 1969 

in Versailles, France 

PhD, French National 

Institute of Health and 

Medical Research (INSERM), 

Department of Microbiology, 

Hôpital Bicêtre, University 

Paris XI, Paris, France 


Laurent Poirel’s interests are mainly focused 

on emerging mechanisms of resistance to 

ß-lactams in Gram-negative bacilli and the 

genetics and epidemiology of novel enzymes 

involved in resistance to expanded-spectrum 

cephalosporins and carbapenems in 

Enterobacteriaceae, Pseudomonas aeruginosa 

and Acinetobacter baumannii. This includes 

the analysis of the genetic vehicles and 

mobility of emerging ß-lactamase genes 

(plasmids, integrons, insertion sequences, 

transposons). 


page 17

Saturday, 

May 1, 2004 

Sunday, 

May 2, 2004 

Scientific Programme Overview 

13 

14 

15 

16 

17 

18 

19 

20 

21 

07 

08 

09 

10 

11 

12 

13 

14 

15 

16 

17 

18 

Auditorium 

Ground Floor 

Small Hall Panorama Hall 

18.00 – 19.30 

Opening 

Ceremony 

p. 176 

19.30 – 21.00 

Welcome 

Reception 

p. 176 

10.00 – 12.00 

Emerging 

respiratory virus 

infections 

14.00 – 15.00 

SARS: health 

care workers 

at risk 

14.00 – 17.30 

Staphylococcal 

small colony 

variants 

Educational 

Workshop 

arranged with 

ASM 


p. 27 

07.15 – 08.15 

Should we treat 

asymptomatic 

bacteriuria 

p. 31 

08.30 – 09.30 �Campylobacter, from obscurity to 

celebrity(Excellence 

Award Lecture) 

p. 31 

– 18.45 

�17.45 

Catastrophes 

after crossing 

species barriers 

p. 41 

10.00 – 12.00 

Future 

targets for 

therapeutic 

interventions 

in sepsis 

14.00 – 15.00 

Helicobacter 

update 2004 

14.00 – 16.00 

ESCMID 

European 

Council 

Meeting 

p. 25 

10.00 – 12.00 

Gram-positive 

pathogens vs. 

new therapies 

Chiron 

14.00 – 15.00 

Methicillinresistant 

1st Floor 

Meeting Hall I Club A 

15.30 – 17.30 

New 

considerations in 

the management 

of serious 

infections 

Wyeth 

10.00 – 12.00 

MRSA – an 

endemic 

challenge for 

hospital 

clinicians 

Pfizer 

14.30 – 17.30 

An introduction 

to pharmako - 

kinetics and pharmaco 

- 

dy namics 

10th ISAP 

Educational 

Workshop 

p. 29 p. 29 

07.15 – 08.15 

Interpretative reading 

of antibiotic 

susceptibility tests 

p. 31 

10.00 – 12.00 

Interventions 

to improve 

antibiotic 

prescription 

14.00 – 15.00 

Prevention of Clos- 

tridium difficile 

p. 37 p. 37 S. aureus p. 37 disease p. 37 

15.30 – 17.30 

15.30 – 17.30 

Strategies in anti- Redefining 

fungal therapy: broad-spectrum 

from prophylaxis antibiotics in 

to curative the new 

treatment millenium 

Gilead 

15.30 – 17.30 

Pan-european 

infectious 

disease 

surveillance 

15.30 – 17.30 

The threat posed 

by Rickettsiales 

and other 

arthropod-borne 

pathogens 

2nd Floor 

Forum Hall 

10.00 – 12.00 

New era in the 

management of 

invasive fungal 

infections 

Merck 

p. 32 p. 32 p. 35 p. 35 p. 33 p. 35 

14.00 – 15.00 

Antimicrobial 

resistance: from 

bench to bedside 

15.30 – 17.30 

Resistance 

surveillance: 

local hotspots, 

global strategies 

Wyeth 


p. 41 p. 41 p. 38 p. 39 p. 41 

p. 37

2 

Meeting Hall V South Hall Chamber Hall 

nd Floor 3rd Floor 

Meeting Hall IV 

14.00 – 17.30 

SNP detection 

and other new 

technologies 

for genetic 

characterisation 

of bacteria and 

infectious disease 

susceptibility 

testing 

ESGEM 

Teaching 

Course 1 

07.15 – 08.15 

Sexually 

transmitted 

infections, HIV and 

travel 

10.00 – 12.00 

AIDS: cost 

effective 

management 

14.00 – 17.30 

Molecular 

basis and 

management 

of MRSA 

ESGNI 

Teaching 

Course 2 

14.00 – 17.30 

Clinical 

diagnostic 

anaerobic 

bacteriology and 

anaerobic 

infections 

ESGCD 

Teaching 

Course 3 

(interactive) 

4th Floor 

Conference Hall 

14.00 – 17.30 

Epidemiology 

and 

management 

of invasive 

fungal 

infections 

EFISG 

Teaching 

Course 4 Registration: 13.00 – 19.00 

p. 27 p. 27 p. 27 p. 27 

07.15 – 08.15 

Diagnosis of 

anaerobes in the 

laboratory: 

costs & benefits? 

10.00 – 12.00 

Sushi delights 

and leisurerelated 

infection 

exposure 

12.15 – 13.45 

ESCMID 

Assembly of 

Members 

14.00 – 15.00 

14.00 – 15.00 

Issues in New issues around 

smallpox pneumococcal 

p. 37 vaccines p. 37 

15.30 – 17.30 

Hepatitis C virus 

infection: 

pathogenesis, 

diagnosis and 

treatment 

15.30 – 17.30 

Host genetics 

and infectious 

diseases 

Official Symposia 

Oral Sessions 

Satellite- & Integrated Symposia 

Meet-the-Expert Sessions, Teaching Courses & Workshops 

Business Meetings 

07.15 – 08.15 

Infection 

control 

07.15 – 08.15 

MDR 

P. aeruginosa 

infections 

p. 31 p. 31 p. 31 p. 31 

10.00 – 12.00 

Viral infections 

in pregnancy 

and neonates: 

from diagnosis 

to management 

(interactive) 

10.00 – 12.00 

Novel 

molecular 

methods for 

bacteriological 

diagnosis 

p. 32 p. 32 p. 32 p. 33 

p. 25 

14.00 – 15.00 

Infections of intra - 

vascular devices 

(interactive) 

p. 37 

15.30 – 17.30 

Multidrug 

resistance in 

Acinetobacter, 

Stenotropho - 

monas and 

Pseudomonas 

(interactive) 

14.00 – 15.00 

Non-molecular 

diagnostic 

methods 

15.30 – 17.30 

HIV: from 

research to 

clinical facts 

14.00 – 15.00 

Pathogenesis of 

infection 

p. 38 p. 38 

15.30 – 17.30 

Communityacquired 

infections: 

unusual 

epidemics and 

update on 

S. pneumoniae 

p. 39 p. 39 p. 39 p. 39 p. 40 

Registration: 07.00 – 18.00 

Foyers 

Exhibition: 08.00 – 18.00 

Exhibition: 13.00 – 21.00 

Poster Session I: 12.00 – 13.00 / Poster Session II: 13.00 – 14.00 

13 

14 

15 

16 

17 

18 

19 

20 

21 

07 

08 

09 

10 

11 

12 

13 

14 

15 

16 

17 

18 


Saturday, 

May 1, 2004 

Sunday, 

May 2, 2004 

page 19

Monday, 

May 3, 2004 

Tuesday, 

May 4, 2004 

Scientific Programme Overview 

07 

08 

09 

10 

11 

12 

13 

14 

15 

16 

17 

07 

08 

09 

10 

11 

12 

13 

14 

15 

16 

Auditorium 

Ground Floor 

Small Hall Panorama Hall 

07.15 – 08.15 

How to advise the 

travelling pregnant 

woman and 

her children 

10.00 – 12.00 

Acute 

exacerbation of 

chronic bronchitis: 

an insidious 

infection 

12.15 – 13.45 

ESGT 

Business 

meeting 

15.30 – 17.30 

Antibiotic 

resistance, 

prevention 

and control in 

Europe 


10.00 – 12.00 

The changing 

faces of 

S. aureus 

15.30 – 17.30 

Group A 

streptococcal 

disease in the 

21 st century 

1st Floor 

Meeting Hall I Club A 

10.00 – 12.00 

New 

technologies for 

microbiological 

diagnostics 

12.15 – 13.45 

ESGARS 

Business 

meeting 

15.30 – 17.30 

Rational 

antibiotic use: 

the future of 

LRTI treatment 

Pfizer 

07.15 – 08.15 

New strategies in 

the management 

of Hepatitis B&C 

10.00 – 12.00 

Molecular 

epidemiology 

and management 

of nosocomial 

outbreaks 

12.15 – 13.45 

ESCAR 

Business 

meeting 

2nd Floor 

Forum Hall 

14.00 – 15.00 

14.00 – 15.00 

14.00 – 15.00 

14.00 – 15.00 

14.00 – 15.00 

Toxoplasmosis in Guidelines for European recommen- Treatment of Viral 

the immunocompromised 

host 

lower respiratory dations for antibiotic 

tract infections resistance surv. 

invasive fungal 

infections 

encephalitis 

p. 49 p. 49 p. 49 p. 50 p. 49 

15.30 – 17.30 

Novel advances 

in antifungal 

therapy 

Vicuron 

10.00 – 12.00 

Effective use 

of carbapenems 

in the management 

of hospitalised 

patients with 

community 

acquired infections 

Aventis 

p. 47 p. 44 p. 44 p. 45 Merck p. 47 

10.00 – 12.00 

Cancer and 

infection: 

a two-way road 

12.15 – 13.45 

EHSG 

Business 

meeting 

14.00 – 16.00 

Biofilms 

15.30 – 17.30 

Lyme 

borreliosis 

p. 51 p. 000 51 p. 55 p. 55 p. 51 

10.00 – 12.00 

Vectortransmitted 

diseases in 

the tropics 

12.15 – 13.45 

EFISG 

Business 

meeting 

14.00 – 16.00 

Current 

problems in 

clinical 

mycology 

08.30 – 09.30 �Mapping the 

co-evolution of man 

and H. pylori 

p. 43 p. 43 

p. 25 p. 25 p. 25 

10.00 – 12.00 

Clinical 

implications of 

early antifungal 

therapy 

Pfizer 

p. 57 

14.00 – 16.00 

Antimicrobial 

susceptibility 

testing of 

difficult 

organisms 

10.00 – 12.00 

Antibiotic 

resistance: 

from ESBL to 

fluoroquinolones 

12.15 – 13.45 

ESGCD 

Business 

meeting 

10.00 – 12.00 

The clinical 

relevance of 

rapid 

diagnostics 

p. 57 p. 57 p. 60 p. 58 p. 57 

12.15 – 13.45 

ESGMD 

Business 

meeting 

p. 25 p. 25 p. 25 p. 25 

p. 62 p. 62 p. 62 

08.30 – 09.30 

Global pandemics: � 

emerging infectious 

diseases 

p. 44 p. 44 

07.15 – 08.15 

07.15 – 08.15 

How to prepare and 

deliver scientific 

communication 

p. 56 

08.30 – 09.30 �Meningococcal infection: 

still a challenge 

in the 21 

New developments 

in the diagnosis 

of invasive mycoses 

p. 56 

08.30 – 09.30 

Evolutionary � 

engineering of antibiotic 

resistance 

st century 

p. 57

Meeting Hall IV 

10.00 – 12.00 

Diarrhoeal 

diseases 

12.15 – 13.45 

ESGNI 

Business 

meeting 

2 nd Floor 3 rd Floor 

Meeting Hall V South Hall Chamber Hall 

10.00 – 12.00 

Macrolides and 

inflammation 

modulation 

in respiratory 

tract infections 

Pliva 

12.15 – 13.45 

ESGARAB 

Business 

meeting 

10.00 – 12.00 

New strategies 

in the manag. 

of fungal 

infections 

Fujisawa 

4th Floor 

Conference Hall 

10.00 – 12.00 

Emerging 

infectious 

diseases 

p. 25 p. 25 p. 25 

14.00 – 15.00 

14.00 – 15.00 

14.00 – 15.00 

� Molecular Anaerobic infections MRSA – Have all 

pathogenesis of ID 

(Young Investigator and antibiotic treat- of us lost the 

Award lectures) ment failures battle? 

14.00 – 15.00 

Sexually 

transmitted 

diseases 

14.00 – 15.00 

Pharmaco kinetics 

and pharmacodynamics 

p. 49 p. 49 p. 49 p. 50 p. 50 

15.30 – 17.30 

Antibiotic 

resistance 

mechanisms 

15.30 – 17.30 

Diagnosis of TB 

and atypical 

pneumonia 

infections in an 

enlarged Europe 

BD 

12.15 – 13.45 

EUCAST 

Business 

meeting 

15.30 – 17.30 

Susceptibility 

testing and 

its role in 

therapy and 

epidemiology 

10.00 – 12.00 

Communicable 

infections: 

surveillance 

systems and 

public health 

issues 

15.30 – 17.30 

Paediatric 

infections and 

vaccines 

15.30 – 17.30 

Tropical and 

parasitic 

diseases 

07.15 – 08.15 

07.15 – 08.15 

07.15 – 08.15 

07.15 – 08.15 

MDR tuberculosis: Cost-effective use 

Clonal analysis of Diagnosis and 

risk factors and of the clinical micro- 

bacterial management of 

management biology laboratory 

populations chronic Lyme disease 

p. 56 p. 56 p. 56 p. 56 

10.00 – 12.00 

The international 

dimension of 

epidemiological 

typing 

12.15 – 13.45 

ESGEM 

Business 

meeting 

14.00 – 16.00 

Tick-borne 

encephalitis 

10.00 – 12.00 

Influence of the 

regulatory 

environment on 

antimicrobial 

resistance 

Bayer 

14.00 – 16.00 

In vitro studies of 

antimicrobial 

agents, fitness & 

virulence factors 

of bacteria 


Oral Sessions 

Satellite- & Integrated Symposia 

Meet-the-Expert Sessions, Teaching Courses & Workshops 


07.15 – 08.15 

07.15 – 08.15 

07.15 – 08.15 

07.15 – 08.15 

How to manage Screening and 

Laboratory diagno- Controversies in 

current rickettsial laboratory 

sis of emerging pediatric 

diseases detection of MRSA 

p. 43 p. 43 

viral diseases 

p. 43 

08.30 – 09.30 

Harnessing RNA � 

interference for 

therapy 

immunisation 

p. 43 

10.00 – 12.00 

Auditing 

antimicrobial 

prescriptions 

in Europe 

12.15 – 13.45 

ESGAP 

Business 

meeting 

p. 44 

p. 44 p. 47 p. 47 p. 45 p. 46 

p. 52 p. 55 p. 51 p. 52 p. 53 

10.00 – 12.00 

Hepatitis 

10.00 – 12.00 

Epidemiology 

and management 

of communityacquired 

pneumonia 

p. 58 p. 60 p. 58 p. 59 p. 59 

p. 25 p. 25 

14.00 – 16.00 

Mycobacterial 

infections: 

diagnosis and 

epidemiology 

14.00 – 16.00 

Infection in the 

immunocom - 

promised host: 

diagnostic tools, 

treatment and 

monitoring 

p. 62 p. 62 p. 63 p. 64 



Foyers 

Exhibition: 09.00 – 18.00 

Exhibition: 09.00 – 14.00 

Poster Session III: 12.00 – 13.00 / Poster Session IV: 13.00 – 14.00 

Poster Session V: 12.00 – 13.00 / Poster Session VI: 13.00 – 14.00 

p. 000 

07 

08 

09 

10 

11 

12 

13 

14 

15 

16 

17 

07 

08 

09 

10 

11 

12 

13 

14 

15 

16 


Monday, 

May 3, 2004 

Tuesday, 

May 4, 2004 

page 21

Introduction to the Scientific Programme 

Meet-the-Expert Sessions 

Sunday through to Tuesday the day will start at 

07.15 with 6 Meet-the-Expert Sessions given by 

experts in their fields. These sessions permit 

the attendees to participate actively in the 

session's topic. After a short presentation the 

expert will open the session for discussion. 

Coffee and tea will be offered. 

Keynote and ESCMID Award Lectures 

At 08.30 each morning, lectures of 60 min will 

be given by opinion leaders in their fields as 

well as by the winner of the ESCMID Award 

for Excellence 2004. The ESCMID Young 

Investigator Award lectures will be held on 

Monday, May 3, 14.00–15.00. 

Symposia 

From 10.00-12.00, from 14.00–15.00 and from 

15.30-17.30 each day, parallel symposia will 

convene renowned speakers from Europe and 

other continents who will cover a wide range 

of recent developments in their field. 

A number of symposia have been organised 

in co-operation with ESCMID study groups 

and some are joint sessions with other 

societies or organisations. 

Symposia arranged by the industry have been 

organised in close co-operation with the 

ECCMID Programme Committee. They are 

an integral part of the scientific programme 

(Integrated Symposia) or presented as a 

Satellite Symposium on Saturday afternoon. 

Oral Sessions 

During the same time slots as the above 

mentioned symposia you will also find 

sessions composed of free submissions, to 

be recognised by the prefix “O” before the 

programme numbers. 

Poster Sessions 

Most of the accepted abstracts are scheduled 

for poster presentation from Sunday to Tuesday. 

The selection was based on a blind review by 

at least 3 experts in each field. The posters will 

be displayed in the foyers of the 3rd and 4th floor 

of the PCC. The poster exhibition is open to all 

participants from 08.00 to 18.00. Please note 

that posters are replaced daily. Poster authors 

must be present at their posters for discussion 

between 12.00 and 13.00 or 13.00 and 14.00, 

depending on the schedule of their session 

(see page 24 for details). 

Guided Poster Walks 

For the second time at ECCMID, guided poster 

walks on selected topics will take place over 

lunch time. For further details please see 

pages 36, 48 and 61. 

Publication Only 

Due to the overwhelming response to the call 

for abstracts, ESCMID was unable to accommodate 

all worthy abstracts for presentation 

during the meeting. Abstracts in this category 

are not included in the Final Programme but 

will be published in the Abstract Book, on the 

CD-ROM and the congress website. 

Abstract Book 

All accepted abstracts as well as abstracts of 

invited speakers (where available) have been 

referenced and published in the Abstract 

Book, which is a supplement to the journal 

Clinical Microbiology and Infection (CMI), the 

official journal of ESCMID. 

CD-ROM 

All abstracts included in the Abstract Book have 

also been recorded on a CD-ROM (sponsored 

by AstraZeneca). In addition to this, a CD-ROM 

including most of the posters presented during 

the congress will be produced after the 

14th ECCMID and mailed to all delegates 

interested in this feature (sponsored by Pfizer). 

You will find vouchers for the collection of 

both CD-ROM's in your congress bag. 

Scientific Programme on the 14th ECCMID 

Website 

The final scientific programme including all 

accepted abstracts is now available at the 

congress' website: 

www.escmid.org/eccmid2004. 

Go to link “scientific programme” to compose 

your personalised programme of lectures. You 

can use the search facility to find keywords, 

speakers and chairpersons. The internet 

corner is located in the industrial exhibition 

on the 2nd floor. 

For your clarification, the following prefixes have been 

used throughout the programme: 

E=Meet-the-Expert Session K=Keynote Lecture 

S=Symposium O= Oral Session P=Poster Session 


page 23

Instructions for Authors 

Audiovisual Equipment / 

Speakers Service Centre (SSC) 

The Speakers’ Service Centre (SSC) is 

centrally located on the 1 st floor of the Prague 

Congress Center (please refer to the overview 

on pages 2/3). 

All lecture rooms will be equipped with a 

PC and a data projector for PowerPoint 

presentations only. Presentations must be 

handed in via floppy disk, CD-ROM, zip drive, 

memory stick or via your own laptop before 

your lecture. 

It is essential for the smooth running of the 

congress that all speakers hand in their 

PowerPoint presentations at least one hour 

before the beginning of the session. 

Enough time must be allowed to check the 

presentation carefully and for the staff to 

enter the data into the system. Speakers 

will have the opportunity to check their 

presentations on PCs available in the SSC. 

Poster Sessions 

Guided Poster Walks 

For the second time at ECCMID, guided poster 

walks on selected topics will take place over 

lunch time. During each of the above poster 

sessions certain abstracts will be presented in 

a moderated poster walk. Chairpersons will 


Publication 

All accepted abstracts will be published in a 

supplement to Clinical Microbiology and 

Infection (CMI), the official journal of ESCMID 

as well as on a CD-Rom. Both items will be 

available during the congress and are 

included in the registration fee. 

Please be aware that the abstracts will 

be printed as they were received by on-line 

electronic submission without editing. 

Starting May 1, 2004, accepted abstracts can 

also be viewed on the congress’ website: 


Following the 14 th ECCMID, a CD-ROM 

including most of the posters presented 

during the congress will be produced and 

mailed to all delegates interested in this 

feature (you will find a voucher in your 

congress bag). Authors of abstracts accepted 

for poster presentation have received 

separate instructions. 

Date of Poster Session Poster No Poster Presence of Poster 

Mounting Authors Removal 

Sunday, May 2, 2004 (I) P430–P674 08.00–09.00 12.00–13.00 17.00–18.00 

Sunday, May 2, 2004 (II) P675–P913 08.00–09.00 13.00–14.00 17.00–18.00 

Monday, May 3, 2004 (III) P914–P1156 08.00–09.00 12.00–13.00 17.00–18.00 

Monday, May 3, 2004 (IV) P1157–P1400 08.00–09.00 13.00–14.00 17.00–18.00 

Tuesday, May 4, 2004 (V) P1401–P1661 08.00–09.00 12.00–13.00 16.00–17.00 

Tuesday, May 4, 2004 (VI) P1662–P1896 08.00–09.00 13.00–14.00 16.00–17.00 

Poster dimensions are: width: 147 cm; height: 97 cm. Posters will be displayed for one full day. Authors are 

requested to be present at their poster during the whole time of the poster session and to mount and remove 

their posters at the above-mentioned times. Posters that have not been removed by the author at 18.00 are 

removed and disposed of by the congress staff. 

select quality posters on the day and discuss 

these in more detail. For further information 

please see pages 36, 48 and 61.

Panorama 

Hall 

14:00–16:00 

Meeting 

Hall V 

12:15–13:45 

Saturday, May 1, 2004 


ESCMID European Council Meeting 

Sunday, May 2, 2004 

ESCMID Assembly of Members 

Monday, May 3, 2004 

Small European Study Group on Toxoplasmosis 

Hall (ESGT) 

12:15–13:45 Business Meeting 

Meeting European Study Group for Antimicrobial 

Hall I Resistance Surveillance (ESGARS) 


Club A ESCMID Study Group on Coxiella, Anaplasma, 

12:15–13:45 Rickettsia and Bartonella (ESCAR) 

Business Meeting 

Meeting ESCMID Study Group on Nosocomial 

Hall IV Infections (ESGNI) 


Meeting European Study Group on Antimicrobial 

Hall V Resistance in Anaerobic Bacteria (ESGARAB) 


South European Committee on Antimicrobial 

Hall Susceptibility Testing (EUCAST) 


Small 

Hall 

12:15–13:45 

Panorama 

Hall 

12:15–13:45 

Tuesday, May 4, 2004 

European Helicobacter Study Group (EHSG) 


European Fungal Infection Study Group (EFISG) 


Club A European Study Group on Clostridium difficile 

12:15–13:45 (ESGCD) 


Forum European Study Group on Molecular 

Hall Diagnostics (ESGMD) 


Meeting European Study Group on Epidemiological 

Hall IV Markers (ESGEM) 


South European Study Group on Antibiotic Policies 

Hall (ESGAP) 



page 25

ABBREVIATED CORE DATA SHEET 

MERREMTM / MERONEMTM (meropenem) 

USES 

Carbapenem antibiotic for the treatment of the following infections caused by a wide variety of single 

or multiple susceptible bacteria: lower respiratory tract, urinary tract, intra-abdominal, gynaecological, skin 

and skin structure, meningitis, septicaemia, empirical treatment including initial monotherapy for presumed 

bacterial infections in host-compromised, neutropenic patients. Meropenem’s spectrum of activity includes 

the majority of clinically significant Gram-positive and Gram-negative aerobic and anaerobic bacteria. 

Intravenous meropenem has been used effectively in patients with cystic fibrosis with chronic lower 

respiratory tract infections, although the causative organisms were not always eradicated. 

PRESENTATION 

IV - vials containing 500mg or 1g meropenem powder for reconstitution and sodium carbonate. 

DOSAGE AND ADMINISTRATION 

IV: 1.5 to 6g daily in 3 divided doses. Dosage is dependent on the susceptibility of the organism, type and 

severity of the infection and condition of patient. Usually 500mg to 1g every 8 hours. 1g iv every 8 hours 

for febrile episodes in neutropenic patients. 2g every 8 hours for meningitis or cystic fibrosis. 

Renal Impairment: Reduce dosage if creatinine clearance

Teaching Courses 

Scientific Programme Saturday, May 1, 2004 

Meeting 

Single nucleotide polymorphism (SNP) 

Hall IV detection and other new technologies for 

T1 genetic characterisation of bacteria and 

14:00 infectious disease susceptibility testing 

Faculty: 

Sylvain Brisse (Paris, F) 

Richard Goering (Creighton, USA) 

Lauren Cowan (Atlanta, USA) 

Neil Woodford (London, UK) 

Marieke Emonts (Rotterdam, NL) 

Sascha Sauer (Berlin, D) 

Mark Achtman (Berlin, D) 

Organised by the ESCMID Study Group on 

Epidemiological Markers (ESGEM) 

Meeting Molecular basis and management of MRSA 

Hall V 

T2 Faculty: 

14:00 Serhat Ünal (Ankara, TR) 

Emilio Bouza (Madrid, E) 

Andreas Voss (Nijmegen, NL) 

Jan Kluytmans (Breda, NL) 

Alex van Belkum (Rotterdam, NL) 

Yesim Cetinkaya Sardan (Ankara, TR) 

Philippe Moreillon (Lausanne, CH) 


Nosocomial Infections (ESGNI) 

Chamber Clinical diagnostic anaerobic bacteriology 

Hall and anaerobic infections (interactive course) 

T3 

14:00 Faculty: 

Jon Brazier (Cardiff, UK) 

Val Hall (Cardiff, UK) 

Mike Wren (London, UK) 


Clostridium difficile (ESGCD) 

Conference Epidemiology and management of invasive 

Hall fungal infections 

T4 

14:00 Faculty: 

Holger Hebart (Tubingen, D) 

Frank-Michael Müller (Heidelberg, D) 

Emmanuel Roilides (Thessalonica, GR) 

Organised by the ESCMID Fungal infection 

Study Group (EFISG) 

Workshops 

Small Staphylococcal small colony variants 

Hall 

14:00 Introduction 

Richard Proctor (Madison, USA) 

S5 Basic mechanisms behind the pathophysiology 

14:05 of S. auerus small colony variants (SCVs) 

infections 

Richard Proctor (Madison, USA) 

S6 Clinical presentation of small colony variants 

15:05 Georg Peters (Munster, D) 

S7 Clinical microbiology of small colony variants 

16:05 Barbara Kahl (Munster, D) 

17:05 Q & A 

Educational Workshop arranged with ASM 

This Workshop is supported by an unrestricted 

educational grant from Bayer AG and 

Ortho-McNeil Pharmaceutical, Inc 


page 27

New Considerations in the Management of Serious Infections 

Utilising Appropriate Antibiotic Therapy to Improve Outcomes 

While Minimising Increases in Antibiotic Resistance 

Saturday May 1, 2004 15:30–17:30 h Meeting Hall I 

AGENDA 

15:30 Introduction & Overview 

Michel Glauser, MD 

Robert Baughman, MD 

15:40 Squeezing the Balloon – The Impact 

of Selected Classes of Antibiotics on 

the Development of Resistance 

Lance Peterson, MD 

16:00 An Evidence-based Evaluation of 

Empiric Antibiotic Therapy in Febrile 

Neutropenic Patients – 

A European Perspective 

Axel Glasmacher, MD 

16:30 Focus on Current Therapeutic 

Alternatives for Febrile Neutropenia 

Eric Bow, MD 

16:50 Advances in the Management of 

Nosocomial Pneumonia – A Review 

of Current Thinking 

Jordi Rello, MD, PhD 

17:20 Conclusion 



REGISTRATION 

To register please visit us online at 

www.scshealthcare.com/2004eccmid 

Satellite Symposium supported by 

Wyeth Pharmaceuticals. 

CO-CHAIRPERSON 


Chair, Medical Faculty, University of 

Lausanne, Switzerland 

CO-CHAIRPERSON 


Professor of Medicine, Department of 

Internal Medicine University of Cincinnati 

Medical Center 

FACULTY 

Lance Peterson, MD 

Director of Microbiology and Infectious 

Disease Research Northwestern Healthcare 

Evanston, IL 

Axel Glasmacher, MD 

Assistant Professor 

University of Bonn 

Eric Bow, MD 

Sections of Infectious Diseases and 

Haematology/Oncology, Head, Department 

of Medical Oncology and Haematology, 

Director, Infectious Control Services, 

CancerCare Manitoba, and Professor and 

Head, Section of Haematology/Oncology, 

Department of Internal Medicine, 

Faculty of Medicine, 

University of Manitoba. 

Jordi Rello, MD, PhD 

Chief, Critical Care Department 

Joan XXIII University Hospital 

Tarragona, Spain

Club A 

Scientific Programme Saturday, May 1, 2004 

An introduction to pharmacokinetics and 

pharmacodynamics 

Chairpersons: Hartmut Derendorf (Gainesville, USA) 

Johann W. Mouton (Nijmegen, NL) 

S8 The general concept of pharmacokinetics and 

14:30 pharmacodynamics 

Hartmut Derendorf (Gainesville, USA) 

S9 Antimicrobial pharmacokinetics: 

14:50 lessons learned from animal models 

William A. Craig (Madison, USA) 

S10 Protein binding and tissue concentrations – 

15:10 do they matter? 

U. Theuretzbacher (Vienna, A) 

S11 PK/PD indices: definitions, how to 

15:30 determine and interpretation 

Johan W. Mouton (Nijmegen, NL) 

S12 Animal models of infection 

15:50 William A. Craig (Madison, USA) 

16:10 Break 

S13 Sub-MIC effects 

16:30 Inga Odenholt (Malmö, S) 

S14 Kill-curve analysis 

16:50 Hartmut Derendorf (Gainesville, USA) 

S15 Clinical implications of PK/PD modelling 

17:10 Paul M. Tulkens (Brussels, B) 

10 th educational workshop of the International 

Society of Anti-Infective Pharmacology (ISAP) 

For further information on this workshop please 

visit the ISAP website at 

www.isap.org/2004/Workshop-Prague 

This workshop is subject to separate registration 

via ISAP (€100) 

Meeting 

Hall I 

Satellite Symposium 

New considerations in the management of 

serious infections: utilising appropriate 

antibiotic therapy to improve outcomes while 

minimising increases in antibiotic resistance 

Chairpersons: Michel Glauser (Lausanne, CH) 

Robert Baughman (Cincinnati, USA) 

15:30 Introduction and overview 

S16 Squeezing the balloon – the impact of 

15:40 selected classes of antibiotics on the 

development of resistance 

Lance Peterson (Evanston, USA) 

S17 An evidence-based evaluation of empiric 

16:00 antibiotic therapy in febrile neutropoenic 

patients – A European perspective 

Axel Glasmacher (Bonn, D) 

S18 Focus on current therapeutic alternatives for 

16:30 febrile neutropenia 

Eric Bow (Manitoba, CAN) 

S19 Advances in the management of nosocomial 

16:50 pneumonia – A review of current thinking 

Jordi Rello (Tarragona, E) 


Satellite symposium arranged by Wyeth 

www.escmid.org/eccmid2004 page 29

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Scientific Programme Sunday, May 2, 2004 


Small Should we treat asymptomatic bacteriuria? 

Hall Experts: Raul Raz (Afula, IL) 

E20 Francisco Soriano (Madrid, E) 

07:15 

Objectives: 

The clinical significance and management of 

asymptomatic bacteriuria (ASB) in different 

groups of patients will be discussed: 

pregnant women, children aged 5-6 years, 

patients undergoing genitourinary procedures 

or with indwelling catheters, patients with 

intermittent catheterization, elderly and 

diabetic patients, healthy school girls and 

young women. 

Club A Interpretative reading of antibiotic 

E21 susceptibility tests 

07:15 Experts: Luis Martinez-Martinez (Santander, E) 

Ian Phillips (Malaga, E) 

Objectives: 

Interactive session for discussion of actual 

cases in which interpretative reading of the 

antibiogram of both Gram-positive and 

Gram-negative pathogens has a major clinical 

impact on reporting susceptibility testing data. 

Meeting Sexually transmitted infections, HIV and 

Hall IV travel: prevention and disease management 

E22 Experts: Philip Tarr (Lausanne, CH) 

07:15 George Schmid (Geneva, CH) 

Objectives: 

Update and discussion of the prevention of 

STIs, vaccines for the HIV infected traveler, 

diarrhea, antiretroviral therapy during travel, 

geographic specific disease prevention, 

management of common questions and 

problems upon return. 

Meeting Diagnosis of anaerobes in the microbiology 

Hall V lab: costs and benefits? 

E23 Experts: Jon Brazier (Cardiff, UK) 

07:15 Arne Rodloff (Leipzig, D) 

Objectives: 

This session will critically assess the 

indications and methods for the diagnosis 

of anaerobes , with special considerations to 

the cost in relation to the potential clinical 

benefits. 

Chamber Infection control 

Hall Experts: Geoffrey Scott (London, UK) 

E24 Niels Frimodt-Møller (Copenhagen, DK) 

07:15 

Objectives: 

To discuss the crucial issues of how to control 

nosocomial spread of infections. By examining 

case studies, to consider how important 

hospital-acquired infections actually are 

(or could be) in the age of MRSA and GRE 

and how to control them. 

Conference 

How to manage multi-drug resistant 

Hall Pseudomonas aeruginosa infections 

E25 Experts: Ian Gould (Aberdeen, UK); 

07:15 Jordi Vila (Barcelona, E) 

Auditorium 

Objectives: 

To discuss how P. aeruginosa acquire 

multiresistance, what are the risk factors 

for acquisition, what is the role of biofilm 

production in resistance and what is best 

empirical treatment based on the above 

mentioned knowledge. 

ESCMID Award of Excellence 

Campylobacter, from obscurity to celebrity 

Chairperson: Marc Struelens (Brussels, B) 

President of ESCMID 

26 

08:30 Jean Paul Butzler (Brussels, B) 

Webcast 

� 

ESCMID Excellence Awardee 2004 

Please see page 15 for further information on the 

ESCMID Award of Excellence 2004 


Auditorium 



Emerging respiratory virus infections 

Chairpersons: Albert Osterhaus (Rotterdam, NL) 

Malik Peiris (Hong Kong, HK) 

S27 The enigma of SARS 

10:00 Malik Peiris (Hong Kong, HK) 

S28 Avian influenza virus infections in humans 

10:30 Ron A.M. Fouchier (Rotterdam, NL) 

S29 Hendra and Nipah viruses: what's new? 

11:00 Fabian Wild (Lyon, F) 

S30 Human metapneumovirus, a newly 

11:30 recognised pathogen 

Albert Osterhaus (Rotterdam, NL) 

Small 

Hall 

Future targets for therapeutic interventions in 

sepsis 

Chairpersons: Thierry Calandra (Lausanne, CH) 

Jean Louis Vincent (Brussels, B) 

10:00 Presentation of the International Sepsis 

Forum Award 2004 

Complement activation during meningococcal 

disease: engagement of lectin and alternative 

pathways and association with disease severity 

Tom Sprong (Nijmegen, NL) 

ISF Awardee 2004 

S31 CRP and PCT as surrogate markers of 

10:10 infection: when and why? 

Konrad Reinhart (Jena, D) 

S32 Endotoxin detection: new test, new hope? 

10:40 Jonathan Cohen (Brighton, UK) 

S33 Glucocorticoids in sepsis: experimental or 

11:05 standard therapy? 

Jean Louis Vincent (Brussels, B) 

S34 Toll-like receptors and NODS 

11:35 Thierry Calandra (Lausanne, CH) 

Joint session arranged with the 

International Sepsis Forum (ISF) 


Meeting 

Hall IV 

AIDS: cost effective management 

Chairpersons: Ethan Rubinstein (Tel Hashomer, IL) 

Patrick Yeni (Paris, F) 

S35 What is standard of care? 

10:00 Patrick Yeni (Paris, F) 

S36 Resistance testing: cost-effectiveness 

10:30 Jean-Claude Schmit (Luxemburg, LUX) 

S37 Toxicity: can we predict it? 

11:00 Philip Tarr (Lausanne, CH) 

S38 What if limited resources? 

11:30 Andrzej Horban (Warsaw, PL) 

Meeting 

Hall V 

Sushi delights and leisure-related infection 

exposure 

Chairpersons: Christoph Hatz (Basle, CH) 

Libuse Kolarova (Prague, CZ) 

S39 Sushi and Sashimi risks 

10:00 Yukifumi Nawa (Miyazaki, JP) 

S40 Anisakis, a European problem? 

10:30 Ignacio Moneo (Madrid, E) 

S41 Worms in South-East Asia: watch out what 

11:00 you eat and where you bath 

Sophie Odermatt-Biays (Vientiane, LAO) 

S42 Swimmer's itch: an emerging water-borne 

11:30 disease 

Libuse Kolarova (Prague, CZ) 

South 

Hall 

Viral infection in pregnancy and neonates: 

from diagnosis to management – 

interactive session 

Chaired by the 3 speakers 

S43 Herpes virus 

10:00 Babill Stray-Pedersen (Oslo, N) 

S44 Parvovirus 

10:40 Patrick Hohlfeld (Lausanne, CH) 

S45 Cytomegalovirus 

11:20 Maren Eggers (Stuttgart, D) 

Interactive Session

Club A 

Oral Sessions 


Intervention to improve antibiotic 

prescription 

Chairpersons: Giorgio Zanetti (Lausanne, CH) 

Vilma Maresova (Prague, CZ) 

O47 Improving the management of inpatients 

10:00 with community-acquired pneumonia: 

controlled before and after study 

G. Barlow, D. Nathwani, F. Williams, S. Ogston, 

K. Lowden, J. Winter, M. Jones, P. Slane, 

E. Myers, F. Sullivan, N. Stevens, R. Duffy, 

P.G. Davey (Dundee, UK) 

O48 The path of least resistance: the value of 

10:12 educating patients and professionals about 

antimicrobial resistance 

G. Madle, P. Kostkova, J. Mani-Saada, 

J. Weinberg (London, UK) 

O49 Attitudes to antibiotic prescribing, resistance 

10:24 and laboratory investigations amongst 

practitioners and patients in the Grampian 

region of Scotland 

I.M. Gould, F.M. MacKenzie, L. Shepherd 

(Aberdeen, UK) 

O50 Antimicrobial usage and resistance trends 

10:36 among Gram-negative nosocomial bacteria: 

a four-year follow-up study in a Belgian 

hospital 

Y. Glupczynski, B. Delaere, C. Baude, P. Gillet, 

Y. DeGheldre, J.D. Hecq (Yvoir, B) 

O51 Interventions to improve vancomycin 

10:48 prescribing – a useful exercise or a waste 

of time? 

F.M. Fitzpatrick, R. Crowley, H. Humphreys, 

E. Smyth (Dublin, IRL) 

O52 A computerised decision support system 

11:00 (TREAT) to reduce inappropriate antibiotic 

therapy of bacterial infections 

E. Tacconelli, M. Paul, M.A. Cataldo, N. Almanasreh, 

A. Zalounina, A. Nielsen, S. Andreassen, 

U. Frank, R. Cauda, L. Leibovici 

(Rome, I; Petah-Tiqva, IL; Freiburg, D; Aalborg, DK) 

O53 Impact of an intervention programme to 

11:12 reduce inappropriate antibiotic prescriptions 

in Southeastern France 

B. Dunais, H. Carsenti Dellamonica, 

M. Roussel Delvallez (Nice, Lille, F) 

O54 Implementation of multidisciplinary antibiotic 

11:24 management teams in Belgian hospitals: 

pilot phase evaluation, 2002–03 

L. Sourdeau, M.J. Struelens, W.E. Peetermans, 

C. Suetens and the Hospital Care Working Group 

of Belgian Antibiotic Policy Coordination 

Commitee (BAPCOC) 

O55 Antimicrobial availability for oncology 

11:36 patients with advanced malignancy in Latin 

America: WHO/PAHO Medical Oncology 

Survey Report 2000-2002 

A. Safdar, I. Torres, C. Cleeland, K. Rolston 

(Houston, USA) 

O56 Household survey of residual antibiotics and 

11:48 beliefs about antibiotics 

C. McNulty, P. Boyle, P. Clappison, A. Fiacco, 

P.G. Davey (Gloucester, St Andrews, Leeds, 

London, Dundee, UK) 

Conference 

Hall 

Novel molecular methods for bacteriological 

diagnosis 

Chairpersons: Alex van Belkum (Leiden, NL) 

Christiane Bébéar (Bordeaux, F) 

O57 A FISH assay with peptide nucleic acid probes 

10:00 for direct identification of blood cultures: 

evaluation in the routine setting 

M. Sogaard, H. Stender, H.C. Schønheyder 

(Aalborg, DK; Woburn, USA) 

O58 Polymerase chain reaction for the diagnosis 

10:12 of osteoarticular infections due to Kingella 

or other fastidious organisms in paediatric 

patients 

C. Ploton, I. Verdier, P. Taylor, Y. Benito, 

F. Vandenesch, J. Berard, A.M. Freydiere (Lyon, F) 

O59 Improved diagnosis of listeriosis by real-time 

10:24 TaqMan-based PCR 

N. Murphy, K. Grant, C. Ohai, J. McLauchlin 

(London, UK) 

O60 Evaluation of diagnostic methods for 

10:36 Mycoplasma pneumoniae and Chlamydia 

pneumoniae using serology, PCR and the BD 

ProbeTec ET System 

B.E.B. Claesson, H. Enroth, S. Elowson, 

M. Hellgren-Leonardsson (Skövde, S) 

O61 Application of different nucleic acid 

10:48 amplification techniques for the detection of 

M. pneumoniae, C. pneumoniae and Legionella 

spp. in respiratory specimens 

K. Loens, T. Beck, K. Dirven, D. Ursi, H. Wouters, 

H. Goossens, M. Ieven (Wilrijk, B) 

O62 Consensus real-time PCR assay for Bordetella 

11:00 pertussis including an internal process control 

provides specific diagnosis, rapid turnaround 

time, high diagnostic yield and enhanced 

surveillance 

N.K. Fry, O. Tzivra, J. Duncan, N. Doshi, 

T.G. Harrison (London, UK) 



O63 MRSA screening by RT-PCR directly from the 

11:12 swab within the same day 

N. Lehn, H.J. Linde, W. Schneider-Brachert, 

P. Kaiser, U. Reischl (Regensburg, D) 

O64 Evaluation of Multiplex PCR Assay to 

11:24 discriminate Staphylococcus aureus from 

coagulase-negative Staphylococci and 

determine methicillin resistance from culture 

S.A.H. Awad, J.P. Burnie, M. Upton 

(Manchester, UK) 

O65 Direct detection of vancomycin-resistant 

11:36 Enterococci from rectal swabs using 

automated DNA extraction and rapid 

real-time PCR: a pilot study 

B.M. Willey, P. Akhavan, N. Kreisworth, 

A. McGeer, T. Mazzulli, P. Ng, A. Sarabia, 

C. Bechard, B. Boekelman, M. Skulnick 

(Toronto, CAN) 

O66 Development of DNA microarrays for 

11:48 detection of macrolide-resistance genes 

M. Cassone, M.M. D'Andrea, F. Iannelli, 

M.R. Oggioni, G.M. Rossolini, G. Pozzi (Siena, I) 

Panorama 

Hall 

Integrated Symposia 

The modern gladiatorial arena: 

Gram-positive pathogens vs new therapies 

Chairpersons: Ian Phillips (Malaga, E) 

Jeff Edwards (Holywell, UK) 



Jeff Edwards (Flintshire, UK) 

S67 Current and emerging serious Gram-positive 

10:10 infections 

Francesco Menichetti (Pisa, I) 

S68 Mechanism of acquisition of high-level 

10:30 resistance to glycopeptides by 

staphylococcus aureus 

Patrice Courvalin (Paris, F) 

S69 Efficacy of current agents and the 

10:50 consequences of resistance 

John Segreti (Chicago, USA) 

S70 The need for new therapeutic agents and 

11:10 strategies – what is in the pipeline? 

Pramod Shah (Frankfurt, D) 

11:30 Programme discussion and summary 


Jeff Edwards (Flintshire, UK) 

Integrated symposium arranged by 

Chiron Biopharmaceuticals 

Meeting MRSA – an endemic challenge for hospital 

Hall I clinicians 

Webcast 

� 

Chairpersons: Gary French (London, UK) 

Jiri Benes (Prague, CZ) 

10:00 Welcome and opening remarks 

Jiri Benes (Prague, CZ) 

S71 Clinical and economic impact of MRSA 

10:05 Hartmut Lode (Berlin, D) 

S72 The evolutionary history of MRSA 

10:30 Mark Enright (Bath, UK) 

S73 Diagnostic challenges of nosocomial and 

10:55 ventilator-acquired pneumonia 

Gary French (London, UK) 

S74 Treatment challenges of nosocomial and 

11:20 ventilator-acquired pneumonia in the ICU 

Richard Wunderink (Chicago, USA) 

11:45 Panel discussion 

11:55 Concluding remarks 

Gary French (London, UK) 

Integrated symposium arranged by Pfizer 

Forum 

New era in the management of invasive 

Hall fungal infections 

Webcast 

� 

Chairpersons: Michael Potter (London, UK) 

Michel Glauser (Lausanne, CH) 

10:00 Opening remarks 

Michel Glauser (Lausanne, CH) 

S75 Challenges and changing epidemiology of 

10:10 invasive fungal infections 

Michael Potter (London, UK) 

S76 Caspofungin – new advances in the treatment 

10:40 of suspected and documented invasive fungal 

infections 

Carole Sable (West Point, USA) 

S77 New clinical evidence and its impact on 

11:10 patient management 

Emilio Bouza (Madrid, E) 

11:40 Closing remarks 

Michael Potter (London, UK) 


Merck, Sharp & Dohme 


Poster Session I 

Topics Session I 

Presence of authors: 12:00–13:00 


– Community-acquired infections: 

focus on unusual epidemics and update 

on S. pneumonia 

★ P430–P459 

– Bacteraemia and endocarditis P460–P476 

– Diagnostic methods – I P477–P491 

– Antimicrobial susceptibility in 

Gram-negative bacteria – I 

P492–P507 

– Antifungal susceptibility studies P508–P520 

– Anitbiotic resistance in respiratory pathogens P521–P527 

– New drugs and novel therapeutic approaches P528–P552 

– MRSA and staphylococci: epidemiology ● P553–P580 

– MRSA and staphylococci: laboratory aspects ● P581–P596 

– Parasitic diseases P597–P616 

– Tropical and parasitic diseases P617–P636 

– Meningitis P637–P644 

– HIV P645–P674 

12:15–13:00 

Guided Poster Walks Session I 

Theme: Community-aquired pneumonia 

Chairpersons: Hartmut Lode (Berlin, D) 

N. Niedermann (Mineola, USA) 

Meeting point: Poster P430 at 12:15 

Posters selected from within the topic marked ★ 

Theme: MRSA & staphylococci 

Chairpersons: Nick Brown (Cambridge, UK) 

Marta Aires de Sousa (Oeiras, P) 


Posters selected from within the topics marked ● 

For further details on the above poster sessions see pages 65–91. 


Poster Session II 

Topics Session II 


– Antimicrobial resistance mechanisms – I ★ P675–P699 

– Molecular bacteriology: 

detection and identification of agents 

P700–P723 

– Molecular bacteriology for Helicobacter pylori P724–P745 

– ESBL and metallo-betalactamases – I P746–P763 

– Enteropathogens P764–P778 

– Linezolid and glycopeptides in 

Gram-positive bacterial infection 

P779–P788 

– Epidemiology of antibiotic susceptibility P789–P802 

– Enterococci and other Gram-positive bacteria P803–P818 

– Molecular and clinical virology 

● P819–P848 

– Clostridium difficile P849–P855 

– Nosocomial infections: nonfermentative 

Gram-negative bacilli – I 

P856–P863 

– Catheter-related infections P864–P874 

– Nosocomial infections: I P875–P889 

– Animal models 

■ P890–P913 

13:00–13:45 

Guided Poster Walks Session II 

Theme: Antimicrobial resistance mechanisms 

Chairpersons: Vincent Jarlier (Paris, F) 

Kevin Towner (Nottingham, UK) 



Theme: Molecular & clinical virology 

Chairpersons: Anti Vaheri (Helsinki, FIN) 

Amalio Telenti (Lausanne, CH) 


Posters selected from within the topic marked ● 

Theme: Animal models 

Chairpersons: Philippe Moreillon (Lausanne, CH) 

Claude Carbon (Paris, F) 


Posters selected from within the topic marked ■

Auditorium 


SARS: health care workers at risk 

Chairpersons: Emilio Bouza (Madrid, E) 

Andreas Voss (Nijmegen, NL) 

S78 Doctor turned patient 

14:00 Allison McGeer (Toronto, CAN) 

S79 Isolation measures 

14:30 Andreas Voss (Nijmegen, NL) 

Small 

Hall 

Helicobacter update 2004 

Chairpersons: Francis Mégraud (Bordeaux, F) 

Alexander Hirschl (Vienna, A) 

S80 Sensing H. pylori in the stomach 

14:00 Richard Ferrero (Paris, F) 

S81 Susceptibility testing, resistance and 

14:30 consequences for the treatment of 

Helicobacter pylori infection 

Alexander Hirschl (Vienna, A) 

Club A 

Official symposium arranged with the 

European Helicobacter Study Group (EHSG) 

Pathogenesis and immunological approaches 

to prevention of Clostridium difficile disease 

Chairpersons: Jon Brazier (Cardiff, UK) 

Klaus Aktories (Freiburg, D) 

S82 Specific polyclonal antibody-enriched whey 

14:00 made from immunised cows for prevention of 

C. difficile relapse 

Ed Kuijper (Leiden, NL) 

S83 The exotoxins of C. difficile 

14:30 Klaus Aktories (Freiburg, D) 

Forum 

Hall 

Offical symposium arranged with the European 

Study Group on Clostridium difficile (ESGCD) 

Antimicrobial resistance: 

from bench to bedside 

Chairpersons: Giuseppe Cornaglia (Verona, I) 

Vlastimil Jindrak (Prague, CZ) 

S84 The microbiologist 

14:00 Fernando Baquero (Madrid, E) 

S85 The clinician 

14:30 Roger Finch (Nottingham, UK) 


Meeting 

Hall IV 

Issues in smallpox 

Chairpersons: Ragnar Norrby (Stockholm, S) 

Bohumir Kriz (Prague, CZ) 

S86 Research and planning for preparedness: 

14:00 US 2004 

Inger Damon (Atlanta, USA) 

S87 Europe needs to be prepared 

14:30 Georgios Gouvras (Luxembourg, LUX) 

Meeting 

Hall V 

New issues around pneumococcal vaccines 

Chairpersons: Heikki Peltola (Helsinki, FIN) 

Jarmila Jelinkova (Prague, CZ) 

S88 Pneumococcal vaccine for the elderly: 

14:00 are we recommending a vaccine of no use? 

Kathrin Mühlemann (Berne, CH) 

S89 New conjugated pneumococcal vaccine: 

14:30 any use in Europe? 

Heikki Peltola (Helsinki, FIN) 

South 

Hall 

Infections of intravascular devices 

Chairpersons: Patrick Francioli (Lausanne, CH) 

David Durack (Sparks, USA) 

S90 Intravenous catheter-related infections 

14:00 Willy Peetermans (Leuven, B) 

S91 Intra-arterial device-related infections 

14:30 Larry Baddour (Rochester, USA) 

Panorama 

Hall 

Interactive Session 

Oral Sessions 

Methicillin-resistant Staphylococcus aureus 

Chairpersons: Waleria Hryniewiecz (Warsaw, PL) 

Jerome Etienne (Lyon, F) 

O92 Methicillin-resistant Staphylococcus aureus 

14:00 reported through the European Antimicrobial 

Resistance Surveillance System (EARSS), 

1999–2002: variation over time and place 

E.W. Tiemersma, S.L.A.M. Bronzwaer, 

O. Lyytikäinen, J.E. Degener, P. Schrijnemakers, 

N. Bruinsma, J.C.M. Monen, W. Witte, 

H. Grundmann and EARSS participants 

O93 Community-acquired Methicillin-resistant 

14:12 Staphylococcus aureus: role of home nursing 

care in a French prospective study 

F.-X. Lescure, G. Locher, M. Eveillard, M. Biendo, 

S. Van Agt, G. Le Loup, Y. Douadi, O. Ganry, 

F. Eb, J.L. Schmit (Amiens, F) 



O94 Carriage of Staphylococcus aureus in family 

14:24 units 

M.V. Boost, M.M. O'Donoghue, F.P. Choy, C. Lo 

(Kowloon, HK) 

O95 A group of related EMRSA15 isolates carrying 

14:36 the Panton-Valentine leukocidin gene 

G.F.S. Edwards, D. Morrison, K. Girvan, 

B. Cosgrove, C. Gemmell (Glasgow, UK) 

O96 Increased community-onset MRSA disease 

14:48 prevalence due to MRSA clones colonising 

the nares of healthy individuals in the 

community 

B.A. Diep, H. Carleton, E. Pan, G. Sensabaugh, 

F. Perdreau-Remington 

(Berkeley, San Francisco, USA) 

Chamber 

Hall 

Non-molecular diagnostic methods 

Chairpersons: Wolfgang Graninger (Vienna, A) 

Dagmar Prusova (Sternberk, CZ) 

O97 External quality assessment for microbiology – 

14:00 participant performance with anaerobes 

C. Walton (London, UK) 

O98 Microbial approach in diagnosis of infection in 

14:12 orthopaedic implants 

E. Bebrova, J. Pilnacek (Kladno, CZ) 

O99 Rapid diagnosis of leptospirosis: identification 

14:24 and use of a 25 amino-acid peptide (PP( R)) 

from the haemolysin-associated protein Hap1 

C. Branger, B. Chatrenet, F. Aviat, I. Suard, 

A. Aubert, G. André-Fontaine (Nantes, Nice, F) 

O100 ELISA-based rapid diagnosis of Rift Valley fever 

14:36 J.T. Paweska, R. Swanepoel (Sandringham, ZA) 

O101 A study to assess the efficacy of a 

14:48 MALDI-TOF-MS database for the rapid 

identification of Bacillus isolates 

C.J. Keys, H.N. Shah, K. Grant, D.J. Dare, 

M. Lunt, M.A. McDowall (London, Manchester, UK) 

Conference 

Hall 

Pathogenesis of infection 

Chairpersons: Jiri Benes (Prague, CZ) 

Philippe Moreillon (Lausanne, CH) 

O102 Participation of gut commensal bacteria and 

14:00 mucosal immunity in pathogenesis of 

inflammatory bowel disease (IBD): 

gnotobiotic models of human disease 

H. Tlaskalová-Hogenová, R. Stepankova, 

H. Kozakova, L. Tuckova, D. Sokol, B. Cukrowska, 

T. Hudcovic, Z. Rehakova, T. Hrncir, P. Heczko, 

M. Strus, H. Uhlig, F. Powrie, P. Bland (Prague, 

CZ; Warsaw, Krakow, PL; Oxford, Bristol, UK) 


O103 Identification and disruption of opuB, a novel 

14:12 bile tolerance locus linked to the virulence 

potential of Listeria monocytogenes 

R. Sleator, C. Hill (Cork, IRL) 

O104 The impact of mechanical ventilation on 

14:24 the treatment with moxifloxacin (MXF) in 

an animal model of pneumonia caused 

by Streptococcus pneumoniae 

P. Charles, D. Croisier, M. Etienne, C. Lequeu, 

L. Piroth, H. Portier, P. Chavanet (Dijon, F) 

O105 The cylA/B genes of the Streptococcus 

14:36 agalactiae hemolysin genecluster encode 

a multidrug resistance ABC transporter 

B. Gottschalk, G. Bröker, M. Kuhn, S. Martin, 

B. Spellerberg (Ulm, Aachen, D) 

O106 Resorbable hydrogel polymer as an 

14:48 antimicrobial delivery system in the 

treatment of Staphylococcus aureus 

experimental osteomyelitis 

M. Rouse, D. Velasquez, S. Bernatchez, 

J. Steckelberg, R. Patel (Rochester, St. Paul, USA) 

Meeting 

Hall I 


Pan-european infectious disease surveillance: 

do we get the needed information for public 

health action? 

Chairpersons: Ronald Haigh (Luxembourg, LUX) 

Matthias Frosch (Wurzburg, D) 

S107 Perspectives for a European CDC 

15:30 Ronald Haigh (Luxembourg, LUX) 

S108 Early warning of influenza epidemics: 

16:00 the EISS network 

William John Paget (Utrecht, NL) 

S109 The EU-MEN-Net: understanding the 

16:30 changing patterns of meningococcal disease 

Matthias Frosch (Wurzburg, D) 

S110 EWGLI-NET: towards Legionella-free 

17:00 travel in Europe 

Carol Joseph (London, UK)

Club A 


The threat posed by Rickettsiales and other 

arthropod-borne pathogens 

Chairpersons: Rudolf Toman (Bratislava, SK) 

Miroslav Petrovec (Ljubljana, SI) 

S111 Climate impacts on ticks as vectors 

15:30 Sarah E. Randolph (Oxford, UK) 

S112 Prophylaxis for tick-borne diseases 

16:00 Jose A. Oteo (Logroño, E) 

S113 Host factors in Q fever 

16:30 Jean-Louis Mege (Marseille, F) 

S114 Intracellular pathogens as bio-terrorism 

17:00 agents 

Didier Raoult (Marseille, F) 

Meeting 

Hall IV 

Official symposium arranged with the ESCMID 

Study Group on Coxiella, Anaplasma, Rickettsia 

and Bartonella (ESCAR) 

Hepatitis C virus infection: 

pathogenesis, diagnosis and treatment 

Chairpersons: Massimo Clementi (Milan, I) 

Stefan Zeuzem (Homburg/Saar, D) 

S115 Hepatitis C virus: origin and evolution in 

15:30 humans 

Peter Simmonds (Edinburgh, UK) 

S116 Humoral response against hepatitis C virus 

16:00 Roberto Burioni, (Ancona, I) 

S117 Treatment of HCV infection 

16:30 Stefan Zeuzem (Homburg/Saar, D) 

S118 HCV/HIV co-infection 

17:00 Vincent Soriano (Madrid, E) 

Meeting 

Hall V 

Host genetics and infectious diseases 

Chairpersons: Ioannis Ioannidis (Ioannina, GR) 

Amalio Telenti (Lausanne, CH) 

S119 Genetics epidemiology 

15:30 Ioannis Ioannidis (Ioannina, GR) 

S120 Genetics of HIV disease 

16:00 Amalio Telenti (Lausanne, CH) 

S121 Prospects and limitation of pharmacogenetics 

16:30 Matthias Schwab (Stuttgart, D) 

S122 Polymorphisms in innate immune genes and 

17:00 host susceptibility to infectious diseases 

Pierre-Yves Bochud (Seattle, USA) 

South 

Hall 

Multidrug resistance in Acinetobacter, 

Stenotrophomonas and Pseudomonas: 

similarities and differences – interactive session 

Chairpersons: Jordi Vila (Barcelona, E) 

Murat Akova (Ankara, TR) 

S123 Resistance mechanisms 

15:30 Jordi Vila (Barcelona, E) 

S124 Epidemiology of multidrug resistance in 

16:00 Acinetobacter, Stenotrophomonas and 

Pseudomonas 

Murat Akova (Ankara, TR) 

S125 Clinical significance and therapeutic difficulties 

16:30 Ian Gould (Aberdeen, UK) 

S126 Prevention and control 

17:00 John P. Quinn (Chicago, USA) 

Chamber 

Hall 

Interactive Session 

Oral Sessions 

HIV: from research to clinical facts 

Chairpersons: Marie Stankova (Prague, CZ) 

Achim Schwenk (London, UK) 

O127 Complement synthesis and activation in the 

15:30 brain of SIV-infected monkeys 

C. Speth, K. Williams, M. Hagleitner, 

S. Westmoreland, M.P. Dierich, H. Maier 

(Innsbruck, A; Boston, Southborough, USA) 

O128 HE2000 decreases inflammatory cytokines 

15:42 and viral load in HIV patients and opportunistic 

infections in late stage AIDS patients 

D. Stickney, C. Reading, A. Garsd, C. Ahlem, 

N. Onizuka-Handa, J. Frincke (San Diego, USA) 

O129 Differential effect of HAART on CD4 and CD8 

15:54 T-cell cytokine production and response to 

CMV antigens in HIV+ patients 

W. Lynn, T. Akerele, R. Moses, S. Lightman 

(London, UK) 

O130 DAPY non-nucleoside inhibitors of HIV-1 

16:06 reverse transcriptase possess high activity in 

microbicide assays and have potential for 

prevention of sexual transmission of HIV 

P.J. Lewi, H.F. Njai, Y. Van Herrewege, 

L. Kestens, G. Vanham, K. Andries, 

M.-P. de Béthune, J. Van Roey, P.A.J. Janssen 

(Vosselaar, Antwerp, Mechelen, B) 



O131 Q151M complex is frequent in HIV-1 non-B 

16:18 subtype isolates of patients living in southern 

Spain 

S. Suarez, M. Alvarez, F. Garcia, M. Martinez, 

J. Parra, F.J.R. Garcia, J. Hernández-Quero, 

M.C. Maroto (Granada, E) 

O132 Comparison of two algorithms in the 

16:30 interpretation of HIV-1 drug resistance 

genotypic data and a novel phenotypic assay, 

virtual phenotype 

C. Nogales, C. Serrano, J.C. Palomares, 

R. Jarana, A. Palacín, C. Almeida, R. Claro, 

S. Bernal, E. Martín-Mazuelos (Seville, E) 

O133 Surgical site infections in HIV-infected 

16:42 patients from the MASTER cohort 

A. Pan, L. Soavi, L. Signorini, B. Cadeo, S. Casari, 

F. Cristini, P. Colombini, S. Lorenzotti, R. Stellini, 

E. Quiros Roldan, G. Carosi on behalf of the 

MASTER Group 

O134 Dyslipidaemia during HIV disease: 

16:54 a comparison of efavirenz- and nevirapinebased 

regimens 

R. Manfredi, L. Calza, F. Chiodo (Bologna, I) 

O135 Comparison between basal parameters in 

17:06 hepatitis due to HCV alone and HCV-HIV 

co-infected patients. A different spectrum of 

the same disease 

J. Guardiola, J. Cadafalch, J. Enriquez, L. Matas, 

A. Mauri, H. Corominas, N. Margall, I. Díaz, 

E. Coma, M. Gurgui, P. Domingo (Barcelona, E) 

O136 Is Legionella a coincidental or opportunistic 

17:18 infection in HIV-positive patients? 

M.L. Pedro-Botet, A. García Cruz, O. Sarroca, 

N. Sopena, M. García Núñez, S. Ragull, 

C. Rey-Joly, M. Sabrià (Badalona, E) 

Conference 

Hall 

Community-acquired infections: 

alert to unusual epidemics and update on 

S. pneumoniae 

Chairpersons: Jiri Beran (Hradec Kralove, CZ) 

Pierre Dellamonica (Nice, F) 

O137 Prevalence, phenotypes, genotypes and 

15:30 molecular epidemiology of macrolideresistant 

clinical isolates of Streptococcus 

pneumoniae in Norway, 2001–2002 

P. Littauer, M. Sangvik, B. Haldorsen, K. Dahl, 

G. Simonsen, D. Caugant, A. Høiby, 

A. Sundsfjord (Tromsø, Oslo, N) 

O138 Trends in resistance of Streptococcus 

15:42 pneumoniae in Europe: an EARSS study 

N. Bruinsma, K. Kristinsson, W. Hryniewicz, 

J.E. Degener, E. Tiemersma, P. Schrijnemakers, 

J. Monen, H. Grundmann and EARSS participants 


O139 Changing patterns of pneumococcal (SP) 

15:54 carriage after an intervention programme 

M. Roussel Delvallez, H. Carsenti Dellamonica, 

C. Laurans, B. Dunais, C. Pradier, P. Toubol, 

P. Bruno, R.J. Courcol, P. Dellamonica 

(Lille, Nice, F) 

O140 Increasing prevalence of multiresistant 

16:06 S. pneumoniae in Europe over a 10-year 

period: Alexander Project 

R. Mera, L. Miller, J. Daniels (Collegeville, USA) 

O141 Comparison of the clonality of penicillin and 

16:18 macrolide non-susceptible pneumococci 

O. Dobay, F. Rozgonyi, S.G.B. Amyes 

(Edinburgh, UK; Budapest, HUN) 

O142 Twenty-five years of tularemia in Norway, 

16:30 1978–2002 

A. Broch Brantsaeter, K. Nygard (Oslo, N) 

O143 Cluster of tetanus cases associated with 

16:42 injecting drug misuse in England 

N.J. Beeching, J.M. White, S. Hahné, 

R.C. George, M.M. Brett, N.S. Crowcroft 

(Liverpool, London, UK) 

O144 The impact of antibiotic therapy on cognitive 

16:54 and emotional changes among neuro - 

brucellosis patients 

S. Eren, G. Bayam, A. Celikbas, O. Ergonul, 

B. Pazvantoglu, N. Baykam, B. Dokuzoguz, 

N. Dilbaz (Ankara, TR) 

O145 A cluster of community-acquired bacter- 

17:06 aemias in an intravenous drug-using 

population due to a novel clonal strain of 

methicillin-resistant Staphylococcus aureus 

C. Jukka, S. Al-Abri, J. Anson, J. Corkill, 

J. Curnow, N.J. Beeching (Liverpool, UK) 

O146 Clinical and microbiological features of 

17:18 Nocardia infection during a period of 7 years 

J. Muñoz, N. Gutiérrez, B. Mirelis, B. Mothe, 

S. Serradell, L. Aragón, R. Paredes, I. Díaz, 

F. Sanchez, M. Español, P. Domingo, M. Gurguí, 

P. Coll (Barcelona, E)

Small 

Hall 



Strategies in antifungal therapy: 

from prophylaxis to curative treatment 

Chairperson: Michael Ellis 

(United Arab Emirates, UAE) 


Michael Ellis (United Arab Emirates, UAE) 

S147 Empiric antifungal therapy: new trends and 

15:50 challenges 

Elias Anaissie (Little Rock, USA) 

S148 Current and future therapeutic strategies with 

16:15 Liposomal Amphotericin B 

Joan Gavalda (Barcelona, E) 

S149 Is combination antifungal therapy a viable 

16:40 option for the future? 

Brian Jones (Glasgow, UK) 

17:05 Panel discussion – Q & A 

17:15 Closing remarks 

Michael Ellis (United Arab Emirates, UAE) 

Panorama 

Hall 

Integrated symposium arranged by Gilead 

Redefining broad-spectrum antibiotics in 

the new millennium 

Chairpersons: Jean Carlet (Paris, F) 

Wolfgang Graninger (Vienna, A) 

15:30 Welcome and introduction 


S152 The role of antibiotics in today’s hospital 

15:40 environment 


S153 Current options for the treatment of bacterial 


David Weber (Chapel Hill, USA) 

S154 Future therapies to overcome tomorrow's 

16:40 challenges 

Jean Carlet (Paris, F) 

17:10 Q & A 


Integrated symposium arranged by Wyeth 

Forum 

Hall 

Resistance surveillance: local hotspots, global 

strategies. A focus on common RTI pathogens: 

the European perspective 

Chairpersons: Peter Appelbaum (Hershey, USA) 

Leonid Stratchounski (Smolensk,RUS) 

S155 Introduction: resistance, surveillance and 

15:30 beyond 

Peter Appelbaum (Hershey, USA) 

15:40 Surveillance hotspots: the highs and lows of 

regional resistance 

Introduction 

Leonid Stratchounski (Smolensk, RUS) 

S156 a) Russia 

15:45 Leonid Stratchounski (Smolensk, RUS) 

S157 b) Central and Eastern Europe 

15:55 Peter Appelbaum (Hershey, USA) 

S158 c) Europe North and South 

16:05 Javier Garau (Barcelona, E) 

S159 d) USA and global 

16:15 Michael R. Jacobs (Cleveland, USA) 

S160 Factors behind resistance 

16:25 Javier Garau (Barcelona, E) 

S161 Surveillance for the future: global strategies 

16:45 to control resistance 

Michael R. Jacobs (Cleveland, USA) 


Peter Appelbaum (Hershey, USA) 

17:15 Discussion 

Auditorium 



Hot topic Symposium 

Catastrophes after crossing species barriers: 

lessons from SARS, influenza … 

Chairperson: Patrick Francioli (Lausanne, CH) 


S162 

17:45 Albert Osterhaus (Rotterdam, NL) 

Webcast 

� 


Sunday, 2 May 2004, 15.30–17.30 

Panorama Hall, Prague Congress Centre, Prague, Czech Republic 

To register, please send your name, credentials, specialty, affiliation, mailing address, 

phone number, fax number, and e-mail address to eccmidregister@gcc.thomson.com 

Overview 

We are now 4 years into the third millennium, yet the problems faced by 

healthcare professionals when treating patients with bacterial infections 

would be familiar to physicians from the previous 2,000 years. The range 

and virulence of bacterial infections is rapidly increasing, and pathogens 

thought to be eradicated are returning to haunt our hospitals across the 

globe. Antibiotics play an important role in treating bacterial infections, 

but many of the currently available antimicrobial agents have a limited 

range of activity or bring a new set of problems: resistance, adverse 

effects and drug interactions. It is time, therefore, to look to the future 

and discuss new and investigational antibiotics that will offer hope to 

physicians treating bacterial infections. This symposium will include a 

concise explanation of the challenges that face healthcare professionals 

treating patients with bacterial infections and review the current 

pharmaceutical options that are available to them. An overview of newly 

licensed and pipeline antibiotics will follow, including products that defy 

definition using traditional descriptors and necessitate a redefinition of 

the term ‘broad-spectrum’. Join the esteemed faculty at this symposium 

to ensure that you are armed with the knowledge of how antibiotics will 

help you and your patients overcome bacterial infections now and for 

many years to come. 

Co-Chairs Jean Carlet 

Wolfgang Graninger 

The role of antibiotics in today’s hospital environment 

Wolfgang Graninger 

Current options for the treatment of bacterial infections 

David Weber 

Future therapies to overcome tomorrow’s challenges 

Jean Carlet 

If you have special needs and wish to discuss 

provisions that may make your learning experience 

more effective, please advise when you register. 

Learning objectives 

Understand the practical 

implications of the epidemiology 

of bacterial pathogens 

Discuss the current therapeutic 

options for the treatment of 

bacterial infections and the 

impact on patient outcomes 

Describe new and investigational 

antibiotics for the treatment of 

patients with serious bacterial 

infections 

Faculty credentials 

Wolfgang Graninger, MD, PhD 

Head 

Department of Infectious Diseases 

Medical University of Vienna 

Vienna, Austria 

David Weber, MD, MPH 

Professor of Medicine and Pediatrics 

School of Medicine 

Professor of Epidemiology 

School of Public Health 

Associate Director 

School of Medicine MD/PhD Program 

University of North Carolina 

Chapel Hill, North Carolina, USA 

Jean Carlet, MD 

Head, Intensive Care Unit 

Hôpital Saint-Joseph 

Paris, France 

Supported by an unrestricted 

educational grant from Wyeth.

Scientific Programme Monday, May 3, 2004 


Small How to advise the travelling pregnant woman 

Hall and her children? 

E163 Experts: Christoph Hatz (Basle, CH) 

07:15 Sophie Odermatt-Biays (Vientiane, LAO) 

Objectives: 

To discuss the pro’s and con’s of pre-travel 

and travel precautions for pregnant women. 

To understand the benefits and health risks of 

travelling during the first years of life. 

To know the regulations (e.g. airline), 

vaccinations and other preventive measures 

for mother to be and children. 

Club A New strategies in the management of 

hepatitis B & C 

E164 Experts: Massimo Clementi (Milan, I) 

07:15 Roberto Burioni (Ancona, I) 

Objectives: 

To address the molecular biology, pathogenic 

potential, diagnosis and treatment of 

infections with hepatitis B and C viruses 

together with the progress that is being 

made towards developing new therapies. 

Meeting How to manage current rickettsial diseases 

Hall IV Experts: Jean-Louis Mege (Marseille, F) 

E165 Didier Raoult (Marseille, F) 

07:15 

Objectives: 

To discuss latest development in the diagnosis 

and management of rickettsial diseases. 

Meeting 

Screening and laboratory detection of MRSA 

Hall V Experts: Fred Tenover, (Atlanta, USA) 

E166 Christina Vandenbroucke-Grauls 

07:15 (Amsterdam, NL) 

Objectives: 

To review the laboratory techniques used 

to detect, identify and confirm methicillin 

resistance in Staphylococcus aureus and 

other staphylococcal species. 

Chamber Laboratory diagnosis of emerging viral 

Hall diseases 

E167 Experts: Ron Fouchier (Rotterdam, NL) 

07:15 Fabian Wild (Lyon, F) 

Objectives : 

To discuss (1) available methods to identify 

and characterise emerging viruses, (2) design 

of diagnostic tests based on limited 

information, and (3) difficulties encountered 

with laboratory diagnosis of emerging viral 

diseases. 

Conference Controversies in immunisation 

Hall Experts: Kathrin Mühlemann (Berne, CH) 

E168 Heikki Peltola (Helsinki, FIN) 

07:15 

Objectives: 

To discuss the relevance of vaccine-induced 

antibody measurements. To understand why 

we don’t already abandon some vaccinations. 

To examine the facts behind several disorders 

claimed to have been due to vaccinations. 


Meeting 

Hall I 

Keynote Lectures 


Interaction between two genomes: 

mapping the co-evolution of man and 

Helicobacter pylori 

Chairperson: Francis Mégraud (Bordeaux, F) 

K169 

08:30 Mark Achtman (Berlin, D) 

Forum 

Hall 

Global pandemics: how well is the global 

village prepared to deal with emerging 

infectious diseases 

Chairperson: Claude Carbon (Paris, F) 

K170 

08:30 Guénaël Rodier (Geneva, CH) 

South 

Hall 

Shooting the messenger: 

harnessing RNA interference for therapy 

Chairperson: Ragnar Norrby (Stockholm, S) 

K171 

08:30 Judy Lieberman (Boston, USA) 

Panorama 

Hall 


The changing faces of S. aureus 

Chairpersons: Marc Struelens (Brussels, B) 

Pavla Urbásˇková (Prague, CZ) 

S172 The threat of glucopeptide-resistant S. aureus 

10:00 Fred C. Tenover (Atlanta, USA) 

S173 The worldwide emergence of hyper virulent 

10:30 MRSA in the community 

Jérome Etienne (Lyon, F) 


S174 MRSA incidence and control in European 

11:00 hospitals 

Pavla Urbásˇková (Prague, CZ) 

S175 Small colony variants of S. aureus – clinical 

11:30 significance and detection challenges 

Barbara Kahl (Munster, D) 

Meeting 

Hall IV 

Diarrhoeal diseases 

Chairpersons: Cynthia L. Sears (Baltimore, USA) 

Elisabeth Nagy (Szeged, HUN) 

S176 Toxigenic Bacteroides fragilis: a commensal 

10:00 launches a diverse attack on the gut 

Cynthia L. Sears (Baltimore, USA) 

S177 Shiga toxin-producing Escherichia coli 

10:30 Helge Karch (Munster, D) 

S178 Enteroaggregative E. coli infections in children 

11:00 Edward Dudley (Baltimore, USA) 

S179 Therapeutic issues, taking into consideration 

11:30 resistance 

Michael Bennish (Mtubatuba, ZA) 

Meeting 

Hall I 

Joint symposium arranged with the 

Infectious Disease Society of America (IDSA) 

New technologies for microbiological 

diagnostics 

Chairpersons: Sascha Sauer (Brussels, B) 

Franklin R. Cockerill (Rochester, USA) 

S180 Advances in the microbiological diagnosis of 

10:00 Aspergillus infection – galactomannan detection 

Johan Maertens (Leuven, B) 


10:30 Streptococcus pyogenes pharyngitis 

Franklin R. Cockerill (Rochester, USA) 


11:00 endocarditis 

Didier Raoult (Marseille, F) 


11:30 biofilm-associated infections 

Robin Patel (Rochester, USA) 

Joint session arranged with the 

ICAAC Program Committee

Club A 

Oral Sessions 


Molecular epidemiology and management of 

nosocomial outbreaks 

Chairpersons: Petra Gastmeier (Hannover, D) 

Leonid Stratchounski 

(Smolensk, RUS) 

O184 Czech epidemic strain of Burkholderia 

10:00 cenocepacia does not belong to ET12 lineage 

S. Vosahlikova, H. Reitzova, O. Cinek, P. Drevinek 

(Prague, CZ) 

O185 Genetic diversity of penicillin-non-susceptible 

10:12 clinical strains of Streptococcus pneumoniae 

isolated in Russia: results of a nationwide 

study 

R.S. Kozlov, I.S. Palagin, M.V. Edelstein, 

L.S. Stratchounski (Smolensk, RUS) 

O186 Relationships between virulence factors of 

10:24 methicillin-resistant Staphylococcus aureus 

and clonal types 

V. Chini, G. Dimitracopoulos, I. Spiliopoulou 

(Patras, GR) 

O187 DNA fingerprinting of Mycobacteria using 

10:36 automated repetitive sequenced-based PCR 

M. Lising, T. Bittner, K. Reece, D. Walton, 

K. Shah, M. Healy (Houston, USA) 

O188 Molecular epidemiological analysis of 

10:48 Mycobacterium tuberculosis isolates reported 

in England in 1998 

A. Gibson, K. Gopaul, J. Anderson, F. LeBrun, 

R. Pitman, Z. Fang, J. Watson, F. Drobniewski 

(London, UK) 

O189 Use of statistical process control for early 

11:00 detection of hospital-acquired outbreak of 

alarm bacteria 

M. Walberg, P. Jenum (Rud, N) 

O190 Failure of classical surveillance strategy to 

11:12 detect a large hospital-wide outbreak of a 

multidrug-resistant Enterobacter cloacae 

M.A. Leverstein-van Hall, H.E.M. Blok, A. Paauw, 

E.M. Mascini, J. Verhoef, A.C. Fluit (Utrecht, NL) 

O191 Investigation of the association between 

11:24 the MRSA colonisation pressure and the 

occurrence of nosocomial MRSA infections 

in 75 German intensive care units 

P. Gastmeier, C. Geffers, M. Behnke, D. Sohr, 

H. Rüden (Hannover, Berlin, D) 

O192 Pseudo-outbreak of Stenotrophomonas 

11:36 maltophilia bacteraemia related to non-sterile 

blood collection vials 

J. Sampaio, S. Sinto, C. Oplustil, J. Amarante, 

M. Biancalana, S. Leao, C. Kiffer, C. Mendes 

(Sao Paulo, BR) 

O193 Compliance with hand disinfection in 

11:48 intensive care units (ICU): the Hawthorne effect 

T. Eckmanns, F. Schwab, R. Wettstein, 

M. Behnke, P. Gastmeier, H. Rüden 

(Berlin, Hannover, D) 

Chamber 

Hall 

Communicable infections: surveillance 

systems and public health issues 

Chairpersons:Jan Galsky (Melnik, CZ) 

Stef Bronzwaer (Luxembourg, LUX) 

O194 Assessing cases for SARS in the Netherlands 

10:00 A. Timen, G.J.J. van Doornum, M. Schutten, 

M.A.E. Conyn-van Spaendonck, J.W.M. van der 

Meer, A.D.M.E. Osterhaus, J.E. van Steenbergen 

(Utrecht, Rotterdam, Bilthoven, Nijmegen, NL) 

O195 The current health and economic burden of 

10:12 varicella in Germany 

P. Wutzler, S. Wagenpfeil, T. Hammerschmidt, 

H. Bisanz, K. Banz, A. Neiss (Jena, Munich, D; 

Basle, CH) 

O196 StAKoB - The German working group of 

10:24 centres for the management of highly 

contagious diseases as part of a preparedness 

network responding to biological hazards 

T. Grünewald, R. Fock, K. Fleischer, G.D. Burchard, 

R. Kurth, B.R. Ruf – German working group of 

centers for the management of highly contagious 

diseases (StAKoB) 

O197 Evidence of shiga-like toxin (stx1, stx2), 

10:36 intimin (eaeA), and hemolysin (hlyA) positive 

E. coli in private and public drinking water 

supplies in Upper Austria – an emerging issue 

of public health? 

M. Halabi, D. Orth, K. Grif, M. Wiesholzer-Pittl, 

J. Schoeberl, M. Kainz, F. Allerberger, 

R. Wuerzner (Ried im Innkreis, Innsbruck, Vienna, A) 

O198 Bacterial meningitis in Denmark. Discrepancy 

10:48 between laboratory registered and notified 

cases 

C.N. Meyer, H.C. Schønheyder, I.S. Samuelsson, 

M. Galle, J.M. Bangsborg, X. Nielsen, N. Høiby 

(Hellerup, Aalborg, Copenhagen, Herlev, DK) 



O199 Results from the first six months of enhanced 

11:00 surveillance of severe Streptococcus pyogenes 

disease in England and Wales 

T. Lamagni, S. Neal, A. Efstratiou (London, UK) 

O200 Streptococcus pyogenes isolates resistant to 

11:12 ciprofloxacin in Spain: clonal diversity and 

appearance of ciprofloxacin-resistant epidemic 

clones 

S. Albertí, G. Cortés, C. García-Rey, C. Rubio, 

F. Baquero, J.A. García-Rodríguez, E. Bouza, 

L. Aguilar, Spanish Surveillance Group for 

Respiratory Pathogens 

O201 External quality assesment of antibiotic 

11:24 susceptibility testing by laboratories 

participating in the European Antimicrobial 

Resistance Surveillance System in 2003 

P. Schrijnemakers, C. Walton, N. Bruinsma, 

G. Kahlmeter, J.E. Degener, J.W. Mouton, 

G. Cornaglia, P. Courvalin, H. Grundmann, 

EARSS participants 

O202 Bacteriologic diagnostics and antibiotic 

11:36 management in German intensive care units: 

data from project SARI (Surveillance of 

Antibiotic Use and Bacterial Resistance in 

German Intensive Care Units) 

E. Meyer, W. Ebner, A. Heininger, F. Daschner 

(Freiburg, Tubingen, D) 

O203 Outpatient systemic antibiotic use in 2002 in 

11:48 Europe 

M. Ferech, M. Elseviers, K. Dirven, R. Vander 

Stichele, H. Goossens 

and the ESAC Project Group 

Conference 

Hall 

Emerging infectious diseases 

Chairpersons: Guénaël Rodier (Geneva, CH) 

Pierre Dellamonica (Nice, F) 

O204 Profile of antibody responses against 

10:00 SARS-coronavirus recombinant proteins and 

their potential use as diagnostic markers 

Y.-J. Tan, P.-Y. Goh, S.G. Lim, W. Hong 

(Singapore, SGP) 

O205 Recombinant N and M protein-based 

10:12 ELISA for detection of antibodies to 

SARS-Coronavirus 

A. Carattoli, P. Di Bonito, F. Grasso, C. Giorgi, 

F. Blasi, A. Cassone (Rome, Milan, I) 


O206 Plague returns to Algeria after an absence of 

10:24 50 years 

E. Bertherat, E. Carniel, A. Chaieb, 

J.-B. Duchemin, E. Tikhomirov, S. Bekhoucha, 

L. Ben Abdallah, F. Razik 

(Geneva, CH; Paris, F; Niamey, NE; Oran, DZ) 

O207 Corynebacterium ulcerans diphtheria in 

10:36 France; a dog as the culprit 

M.-F. Lartigue, X. Monnet, P.A.D. Grimont, 

J.-J. Benet, P. Nordmann 

(Le Kremlin-Bicêtre, Paris, Maisons-Alfort, F) 

O208 Group B Streptococcus necrotising fasciitis: 

10:48 an emerging disease? 

C.-H. Wong, Y.-S. Wang, A. Kurup, K.-C. Tan 


O210 Changing microbiological profile of infective 

11:00 endocarditis in Greece during the last 17 years 

E. Giannitsioti, I. Skiadas, K. Kanavos, 

A. Antoniadou, H. Giamarellou – 

Hellenic Endocarditis Study Group 

O211 New acute tick-borne rickettsiosis caused by 

11:12 Rickettsia heilongjiangensis in the Russian 

Far East 

O. Mediannikov, Y. Sidelnikov, L. Ivanov, 

E. Mokretsova, P.-E. Fournier, I. Tarasevich, 

D. Raoult (Moscow, Khabarovsk, RUS; Marseille, F) 

O212 Laribacter hongkongensis in fish is associated 

11:24 with gastroenteritis and traveller's diarrhoea 

P.C.Y. Woo, S.K.P. Lau, J.L.L. Teng, T.L. Que, 

R.W.H. Yung, W.K. Luk, R.W.M. Lai, W.T. Hui, 

S.S.Y. Wong, H.H. Yau, K.Y. Yuen (Hong Kong, HK) 

O213 Diarrhoea in Danish children under five years 

11:36 of age: a case-control study 

B. Olesen, J. Neimann, K. Mølbak, B. Böttiger, 

S. Ethelberg, P. Schiellerup, C. Jensen, 

M. Helms, F. Scheutz, K.E.P. Olsen, E. Petersen, 

P. Gerner-Smidt (Hillerød, Copenhagen, DK)

Small 

Hall 



Acute exacerbation of chronic bronchitis 

(AECB): an insidious infection 

Chairpersons: Francesco Blasi (Milan, I) 

Antoni Torres (Barcelona, E) 


S214 Epidemiology features: regional aspects and 

10:05 patient challenges 

Rafael Canton (Madrid, E) 

S215 PK/PD features for optimisation of antibiotic 

10:30 therapy 


S216 AECB management: state of the art – 

10:55 new European guidelines 

Antoni Torres (Barcelona, E) 

S217 AECB: therapeutic options 

11:20 Hartmut Lode (Berlin, D) 

11:45 Summary, conclusions & discussion 

South 

Hall 


Aventis Pharma 

New strategies in the management of fungal 

infections 

Chairpersons: David W. Denning (Manchester, UK) 

Jo-Anne H. van Burik 

(Minneapolis, USA) 


David W. Denning (Manchester, UK) 

S218 Review of echinocandin antifungal drugs 

10:05 David W. Denning (Manchester, UK) 

S219 Clinical pharmacokinetics of micafungin 

10:25 Nasrullah A. Undre (Munich, D) 

S220 Micafungin for prophylaxis of fungal 

10:50 infections in high-risk patients 

Jo-Anne H. van Burik (Minneapolis, USA) 

S221 Fungal infections in paediatrics – 

11:10 new perspectives 

Frank-Michael Müller (Heidelberg, D) 




Integrated symposium arranged by Fujisawa 

Forum 

Hall 

Effective use of carbapenems in the 

management of hospitalised patients with 

community-acquired infections 

Chairperson: Gert Höffken (Dresden, D) 

10:00 Opening remarks 

Gert Höffken (Dresden, D) 

S222 Role of ertapenem in the evolving 

10:05 management of CAP 


S223 Ertapenem: effective and appropriate 

10:35 antimicrobial therapy for intra-abdominal 

infections 

Christina Chan (Whitehouse Station, USA) 

S224 Carbapenems in an era of antibiotic resistance 

10:55 George Karam (Baton Rouge, USA) 

S225 How will ertapenem affect the resistance 

11:20 ecology? 

David Livermore (London, UK) 




Meeting 

Hall V 


Merck, Sharp & Dohme 

Macrolides and inflammation modulation in 

respiratory tract infections 

Chairpersons: Guy W. Amsden (Cooperstown, USA) 

Thomas M. File (Akron, USA) 

S226 Immunomodulatory effects of macrolides 

10:00 Ognjen Culic (Zagreb, HR) 

S227 Biphasic modulation by azithromycin 

10:30 of human neutrophil function: 

implications for therapy 

Michael J. Parnham (Zagreb, HR) 

S228 Macrolides and inflammation modulation in 

11:00 the treatment of respiratory tract infections 

Guy W. Amsden (Cooperstown, USA) 

S229 Clinical use of macrolides in the treatment of 

11:30 RTIs: focus on azithromycin 

Thomas M. File (Akron, USA) 

Integrated symposium arranged by Pliva 


Poster Session III 

Topics Session III 



– New drugs 

★ P914–P940 


antibiotic susceptibility 

P941–P951 

– Molecular bacteriology: borrelia P952–P956 


characterisation of agents 

P957–P976 

– Urinary tract infections P977–P985 

– Mycology: Candida and aspergillosis ● P986–P1009 

– Molecular bacteriology: Staphylococcus P1010–P1021 

– Progress in pharmacokinetics 

and pharmacodynamics – I 

P1022–P1049 

– Pathogenesis P1050–P1068 

– Insights into hepatitis P1069–P1086 

– Streptococci: resistance and epidemiology P1087–P1099 

– Resistance in Pseudomonas and 

other Gram-negative bacilli 

P1100–P1129 

– S. pneumoniae: 

resistance and epidemiology 

■ P1130–P1156 

12:15–13:00 

Guided Poster Walks Session III 

Theme: New drugs 

Chairpersons: Jeff Edwards (Holywell, UK) 

Leonid Stratchounski (Smolensk, RUS) 



Theme: Mycology: Candida and aspergillosis 

Chairpersons: David Denning (Manchester, UK) 




Theme: S. pneumoniae: resistance and epidemiology 

Chairpersons: Javier Garau (Barcelona, E) 

Peter Appelbaum (Hershy, USA) 


Posters selected from within the topic marked ■ 

For further details on the above poster sessions see pages 92–119 


Poster Session IV 

Topics Session IV 


– Antibiotic therapy and public health issues ★ P1157–P1180 

– Antibiotic use and surveillance 

★ P1181–P1200 

– Vaccines and immunisation P1201–P1206 


Gram-negative bacteria – II 

P1207–P1227 

– Viral diseases P1228–P1251 

– Diagnostic methods – II P1252–P1272 

– Mycobacterial disease: 

pathogenesis and therapy 

● P1273–P1282 

– Mycobacterial disease: 

multiresistant tuberculosis 

● P1283–P1295 

– Miscellaneous issues P1296–P1301 

– Paediatric infections P1302–P1314 

– Immunology and immunotherapy P1315–P1323 

– Host defenses P1324–P1342 

– Nosocomial infections: 

Gram-positive micro organisms 

P1343–P1357 


multiresistant Gram-negative bacteria 

P1358–P1373 

– Surveillance studies 

■ P1374–P1400 

13:00–13:45 

Guided Poster Walks Session IV 

Theme: Antibiotic use and public health issues 

Chairpersons: Ian Gould (Aberdeen, UK) 

Giorgio Zanetti (Lausanne, CH) 


Posters selected from within the topics marked ★ 

Theme: Mycobacterial disease 

Chairpersons: Christina Vandenbrouke-Grauls (Amsterdam, NL) 

Mark Woodhead (Manchester, UK) 



Theme: Surveillance studies 

Chairpersons: Dominique Monnet (Copenhagen, DK) 



Posters selected from within the topic marked ■

Meeting 

Hall IV 


ESCMID Young Investigator Awards 

Towards understanding the molecular 

pathogenesis of infectious diseases 

Chairperson: Roger Finch (Nottingham, UK) 

Chairman ESCMID Award 

Committee 

230 Interactions between the subunits 

14:00 of herpesvirus DNA polymerases: 

towards new antiviral targets 

Arianna Loregian (Padua, I) 

231 Understanding how Listeria 

14:30 monocytogenestarget and cross 

host barriers 

Marc Lecuit (Paris, F) 

Small 

Hall 

The ESCMID Young Investigator Awards are 

sponsored by Pfizer. 

Please see pages 15/16 for further information. 


Toxoplasmosis in the immunocompromised 

host 

Chairpersons: Birgitta Evengård (Stockholm, S) 

Patrick Hohlfeld (Lausanne, CH) 

S232 Epidemiology and diagnosis 

14:00 Hervé Pelloux (Grenoble, F) 

S233 Pathogenesis and treatment 

14:30 Birgitta Evengård (Stockholm, S) 

Panorama 

Hall 

Official symposium arranged with the European 

Study Group on Toxoplasmosis (ESGT) 

Guidelines for lower respiratory tract 

infections 

Chairpersons: Margareta Ieven (Edegem, B) 


S234 New European Respiratory Society (ERS) 

14:00 guidelines 


S235 Is there any evidence that community- 

14:30 acquired pneumonia (CAP) guidelines make 

a difference? 

Francesco Blasi (Milan, I) 

Meeting 

Hall I 

European recommendations for antibiotic 

resistance surveillance 

Chairpersons: Kevin Towner (Nottingham, UK) 

Jordi Vila (Barcelona, E) 

S236 Recommendations for data retrieval and entry 

14:00 Fernando Baquero (Madrid, E) 

S237 Recommendations for data analysis and 

14:30 presentation 

Giuseppe Cornaglia (Verona, I) 

Forum 

Hall 

Official symposium arranged with the 

European Study Group for Antimicrobial 

Resistance Surveillance (ESGARS) 

Viral encephalitis 

Chairpersons: Zdenek Hubalek (Brno, CZ) 

Antti Vaheri (Helsinki, FIN) 

S238 West Nile virus 

14:00 Zdenek Hubalek (Brno, CZ) 

S239 Japanese encephalitis – 

14:30 West Nile virus' ugly sister 

Tom Solomon (Liverpool, UK) 

Meeting 

Hall V 

Anaerobic infections and antibiotic treatment 

failures 

Chairpersons: Carl Erik Nord (Stockholm, S) 

David R. Snydman (Boston, USA) 

S240 Interactions of aerobic and anaerobic bacteria 

14:00 as causes for antibiotic treatment failures 

Arne Rodloff (Leipzig, D) 

S241 Treatment failures in anaerobic infections due 

14:30 to antimicrobial resistance 

David R. Snydman (Boston, USA) 

South 

Hall 


Study Group on Antimicrobial Resistance in 

Anaerobic Bacteria (ESGARAB) 

MRSA – Have all of us lost the battle? 

Chairpersons: Andreas Voss (Nijmegen, NL) 

Marc Struelens (Brussels, B) 

Two points of view: 

S242 The battle is lost – moderate actions are 

14:00 enough 

Nick Brown (Cambridge, UK) 

S243 Time to fight – the full-blown attack 

14:30 Christina Vandenbrouck-Grauls (Amsterdam, NL) 


Club A 

Oral Sessions 


Treatment of invasive fungal infections 

Chairpersons: Olivier Lortholary (Paris, F) 


O244 Safety, tolerance and plasma concentrations 

14:00 of voriconazole in immunocompromised 

paediatric patients 

H. Kolve, T. Lehrnbecher, K. Ehlert, 

M. Paulussen, S. Bielack, J. Vormoor, T.J. Walsh, 

A.H. Groll (Münster, Frankfurt, D; Bethesda, USA) 

O245 Voriconazole compared to a strategy of 

14:12 amphotericin B followed by fluconazole for 

treatment of candidaemia in non-neutropenic 

patients 

B.J. Kullberg, P. Pappas, M. Ruhnke, C. Viscoli, 

J.D. Cleary, E. Rubinstein, L.W.P. Church, 

J.M. Brown, J.H. Rex, F. Hilton, I. Oborska, 

M. Hodges, H.T. Schlamm, J. Sobel 

(Nijmegen, NL; Birmingham, USA; Berlin, D; 

Genoa, I; Jackson, USA; Tel Hashomer, IL; 

Charleston, USA; Diepkloof, ZA; Houston, USA; 

Sandwich, UK; New London, Detroit, USA) 

O246 Regimens and outcomes of current 

14:24 approaches to secondary prophylaxis after 

proven or probable invasive fungal infections. 

A multinational case registry 

O.A. Cornely, S. Reuter, J. Maertens, D. Arenz, 

J. Franz, A.J. Ullmann, R. Martino, A. Böhme, 

S. Cesaro, X. Schiel, H. Auner, R. Chopra, 

A. Gratwohl, W. Jedrzejczak, M. Karthaus, 

M.G. Kiehl, W. Krüger, G. Maschmeyer, 

A. Nosari, G. Silling for the ID Working Party 

of the German Society for Hematology and 

Oncology 

O247 Therapy with polyenes and echinocandins in 

14:36 a model of cerebral aspergillosis 

K.V. Clemons, M. Espiritu, R. Parmar, 

D.A. Stevens (San Jose, USA) 

O248 Posaconazole for fusarium infections: 

14:48 results of two clinical studies 

I. Raad, R. Hachem, R. Herbrecht, G. Corcoran 

(Houston, USA; Strasbourg, F; Kenilworth, USA) 


Chamber 

Hall 

Sexually transmitted diseases 

Chairpersons: Miroslav Votava (Brno, CZ) 

George Schmid (Geneva, CH) 

O249 Performance of the Aptima® CT assay for 

14:00 Chlamydia trachomatis and Aptima GC 

Assay® for Neisseria gonorrhoeae using 

patient- and clinician-collected vaginal swabs 

J. Schachter, M. Chernesky, D. Willis, P. Fine, 

E.W. Hook, D.H. Martin, D. Fuller, J. Jordan, 

W. Janda (San Francisco, USA; Hamilton, CAN; 

Jacksonville, Houston, Birmingham, New 

Orleans, Indianapolis, Pittsburgh, Chicago, USA) 

O250 Molecular techniques in diagnostics of 

14:12 Chlamydiae – benefits and limits 

E. Pavlík, A. Pavlíková, J. Kremen, V. Husáková, 

E. Procházková-Francisci (Prague, CZ) 

O251 Clinical relevance of PCR tests for detection of 

14:24 Treponema pallidum subsp. pallidum 

J. Kremen, J. Stribrná, E. Pavlík, M. Knappová, 

H. Zákoucká, V. Kastánková, Z. Contofalská 

(Prague, CZ; Kosice, SK) 

O252 Laboratory diagnosis of Trichomonas 

14:36 vaginalis with culture, ELISA and (real-time) 

PCR 

B. Mulder, M. Homaei, H. Wilke, R. Hendrix 

(Enschede, NL) 

O253 Efficacy of long-term suppressive therapy 

14:48 with valacyclovir in recurrent genital herpes 

S.V. Sekhin, V.M. Averchenkov, 

N.A. Petrochenkova, N.Y. Melekhova, 

L.S. Stratchounski (Smolensk, RUS) 

Conference 

Hall 

Pharmacokinetics and pharmacodynamics 

Chairpersons: Pascal Chavanet (Dijon, F) 

George Drusano (New York, USA) 

O254 Plasma and intrapulmonary concentrations 

14:00 of oritavancin and vancomycin in normal 

healthy adults 

K.A. Rodvold, M.H. Gotfried, J.S. Loutit, 

S.B. Porter (Chicago, Phoenix, Brisbane, USA) 

O255 Should we routinely monitor beta-lactam 

14:12 serum concentrations during the treatment 

of endocarditis? 

P. Tattevin, O. Tribut, C. Arvieux, M. Dupont, 

R. Flicoteaux, G. Léveiller, Y. Le Tulzo, 

C. Michelet (Rennes, F)


O256 Utility of the 750 mg dose of levofloxacin 

14:24 against Streptococcus pneumoniae as 

assessed by Monte Carlo simulation and 

expectation over a large MIC distribution 

G. Drusano, E. Grant (Albany, Raritan, USA) 

O257 Use of pharmacodynamics and Monte Carlo 

14:36 simulations to predict clinical cure of 

Pseudomonas aeruginosa infection 

S. Valot, M. Etienne, D. Croisier, L. Piroth, 

H. Portier, P. Chavanet (Dijon, F) 

O258 Development of a pharmacokinetic/ 

14:48 pharmacodynamic model to characterise 

the in vitro activity and dose-response 

relationships of daptomycin and linezolid 

against Vancomycin-Resistant Enterococci 

(VRE) using subpopulation analysis 

S. Bajic, B.M. Booker, P. Kelchlin, A. Forrest, 

P.F. Smith (Buffalo, USA) 

Small 

Hall 


Antibiotic resistance, prevention and control 

in Europe 


Herman Goossens (Antwerp, B) 

S259 Epidemiology of antibiotic resistance across 

15:30 Europe 

Herman Goossens (Antwerp, B) 

S260 Antibiotic policies and consumption in 

16:00 European hospitals 

Fiona MacKenzie (Aberdeen, UK) 

S261 Infection control policies in European hospitals 

16:30 Marc Struelens (Brussels, B) 

S262 Molecular typing to control antibiotic resistance 

17:00 Kevin Towner (Nottingham, UK) 

Official symposium arranged with the Antibiotic 

Resistance – Prevention and Control Steering 

Group (ARPAC) 

Panorama 

Hall 

Group A streptococcal disease in the 

21 st century 

Chairpersons: Claes Schalén (Lund, S) 

Paula Kriz (Prague, CZ) 

S263 Strep-EURO project: progress report 

15:30 Aftab Jasir (Lund, S) 

S264 Severe group A streptococcal infections in 

16:00 Europe: microbiological and epidemiological 

aspects 

Androulla Efstratiou (London, UK) 

S265 Multilocus sequence typing of group A 

16:30 streptococci in invasive infections 

Paula Kriz (Prague, CZ) 

S266 Pathogenic aspects on severe group A 

17:00 streptococcal infections 

Claes Schalén (Lund, S) 

Forum 

Hall 

Lyme borreliosis 

Chairpersons: Gerold Stanek (Vienna, A) 

Jiri Beran (Hradec Kralove, CZ) 

S267 Biology of Borrelia and epidemiology of disease 

15:30 Gerold Stanek (Vienna, A) 

S268 Acute and chronic manifestations 

16:00 Franc Strle (Ljubljana, SI) 

S269 The use and misuse of diagnostic tools 

16:30 Henrik Nielsen (Aarborg, DK) 

S270 Treatment and prevention 

17:00 Gary Wormser (New York, USA) 

South 

Hall 

Susceptibility testing and its role in therapy 

and epidemiology 

Chairpersons: Gunnar Kahlmeter (Växjö, S) 

Derek Brown (Cambridge, UK) 

S271 Susceptibility testing of bacteria – 

15:30 do breakpoints predict therapeutic outcome? 


S272 Susceptibility testing of fungi – 

16:00 do breakpoints predict therapeutic outcome? 

J. Peter Donnelly (Nijmegen, NL) 



S273 Antimicrobial resistance frequencies using 

16:30 EUCAST epidemiological cut-off values 

compared to national breakpoints when 

applied to the EARSS database 

Gunnar Kahlmeter (Växjö, S) 

S274 Genotypic versus phenotypic resistance 

17:00 Patrice Courvalin (Paris, F) 

Meeting 

Hall IV 


Committee on Antimicrobial Susceptibility 

Testing (EUCAST) 

Oral Sessions 

Antibiotic resistance mechanisms 

Chairpersons: Ronald Jones (North Liberty, USA) 

Sylvain Brisse (Paris, F) 

O275 Diversity and evolution of class A 

15:30 chromosomal beta-lactamase genes in 

Klebsiella pneumoniae 

S. Haeggman, S. Löfdahl, A. Paauw, J. Verhoef, 

S. Brisse (Solna, S; Netherlands, Utrecht, NL; 

Paris, F) 

O276 Resistance to beta-lactam antibiotics in 

15:42 Staphylococcus aureus 

C. Fuda, S. Mobashery (Notre Dame, USA) 

O277 Analysis of the flexible loop of the SPM-1 

15:54 metallo-beta-lactamase in substrate binding 

and hydrolysis 

T. Murphy, J. Spencer, A. Simm, R. Jones, 

T. Walsh (Bristol, UK; North Liberty, USA) 

O278 Hospital outbreak of an imipenem-resistant 

16:06 VIM-2 encoding Acinetobacter DNA group 

14 TU strain in a German teaching hospital 

M. Toleman, H. Seifert, L. Dijkshoorn, R. Reinert, 

T. Walsh (Bristol, UK; Cologne, D; Leiden, NL; 

Aachen, D) 

O279 Defining the meropenem susceptible 

16:18 population in Pseudomonas aeruginosa by 

analysing expression of resistance genes in 

clinical isolates with different levels of 

meropenem resistance 

C. Giske, C. Borén, B. Wretlind, G. Kronvall 

(Stockholm, Växjö, S) 

O280 Overexpression of Rob increases MIC to 

16:30 norfloxacin by upregulation of the MdfA 

efflux pump in Escherichia coli in vitro 

H.J. Linde, C. Irtenkauf, M. Arnold, N. Lehn 

(Regensburg, D) 


O281 Mechanisms of resistance to co-amoxiclav in 

16:42 clinical isolates of Escherichia coli 

B.G. Elisha, E. Nelson, Y. Ghebremariam, 

H. Segal (Cape Town, ZA) 

O282 Loss of function mutations in smeT lead to 

16:54 multiresistance in Stenotrophomonas 

maltophilia 

V. Gould, M. Avison (Bristol, UK) 

O283 Evaluation of differential gene expression in 

17:06 antimicrobial susceptible and resistant clinical 

isolates of Klebsiella pneumoniae by DNA 

microarray analysis 

A. Doménech-Sánchez, Y. Dong, E.W. Triplett, 

S. Albertí, L. Martínez-Martínez, V.J. Benedí 

(Palma de Mallorca, E; Madison, USA; Santander, E) 

O284 Molecular basis for trimethoprim resistance in 

17:18 clinical urinary isolates 

M. Grape, L. Sundström, G. Kronvall 

(Stockholm, Uppsala, S) 

Chamber 

Hall 

Paediatric infections and vaccines 

Chairpersons: Vilma Maresova (Prague, CZ) 


O285 Analysis of rotavirus strains detected in 2003 

15:30 in a Mantua hospital (Italy) 

V. Martella, V. Terio, F. Fabozzi, A. Cirani, 

F. Cariola, G. Gambaretto, A. Caroli, G. Elia, 

F. Rossano, A. Pratelli, C. Buonavoglia 

(Valenzano, Mantua, Castellana Grotte, Naples, I) 

O286 Eye lesions associated with congenital 

15:42 toxoplasmosis: long-term follow-up of 

327 children 

M. Wallon, C. Binquet, L. Kodjikian, J. Garweg, 

J. Fleury, C. Quantin, F Peyron 

(Lyon, Dijon, F; Berne, CH) 

O287 Quick resolving of unilateral middle ear 

15:54 effusion in acute otitis media monitored daily 

with tympanometry 

T. Kontiokari, M. Renko, M. Uhari (Oulu, FIN) 

O288 M-serotypes, sensitivity to antibiotics and 

16:06 pyrogenic exotoxin genes of Streptococcus 

pyogenes invasive strains isolated in a Greek 

paediatric hospital during 1996–2002 

G. Chronopoulou, L. Zachariadou, N. Petropoulou, 

A. Tanna, A Efstratiou, A. Pangalis 

(Athens, London, GR) 

O289 Penicillin for children affected with acute sore 

16:18 throat with or without group A beta-haemolytic 

streptococci in primary care 

S. Zwart, M.M. Rovers, R.A. de Melker, 

A.W. Hoes (Utrecht, NL)


O290 Pertussis incidence in the Netherlands after 

16:30 introduction of an acellular booster 

vaccination at 4 years of age 

S.C. de Greeff, J.F.P. Schellekens, F.R. Mooi, 

H.E. de Melker (Bilthoven, NL) 

O291 Intensified surveillance after introduction of 

16:42 vaccination against meningococcal C disease 

in the Netherlands 

S.C. de Greeff, L. Spanjaard, M. van Deuren, 

H. Ruijs, J. Dankert, A. Timen, M. de Vries, 

L. Schouls, H.E. de Melker (Bilthoven, 

Amsterdam, Nijmegen, Tiel, Utrecht, NL) 

O292 Vaccination against hepatitis B in newborns 

16:54 of HBsAg positive mothers 

L. Roznovsky, I. Orsagova, I. Lochman, 

L. Lukacova, A. Zjevikova, A. Sulakova, 

L. Pliskova, A. Kloudova, J. Chovancik 

(Ostrava, Hradec Kralove, CZ) 

O293 Protective effect in monkeys following 

17:06 immunisation with a live attenuated chimeric 

flavivirus against tick-borne encephalitis 

N.S. Pripuzova, L.V. Gmil, T.I. Dzhivanyan, 

A.A. Rumyantsev, V.A. Lashkevich, G.G. Karganova 

(Moscow, RUS; Bethesda, USA) 

O294 HLA polymorphisms and T cell cytokine 

17:18 responses to processed HLA class II measles 

virus peptides: the rationale for a measles 

peptide vaccine 

I.G. Ovsyannikova, K.L. Johnson, R.A. Vierkant, 

D.C. Muddiman, G.A. Poland (Rochester, USA) 

Conference 

Hall 

Tropical and parasitic diseases 

Chairpersons: Roxana Filip (Iasi, RO) 

Christoph Hatz (Basle, CH) 

O295 Post-travel related hospitalisation in Israel 

15:30 S. Stienlauf, G. Segall, Y. Sidi, E. Schwartz 

(Tel Hashomer, IL) 

O296 Treatment of uncomplicated imported 

15:42 falciparum malaria in Italy 

N. Saleri, A. Matteelli, M. Gulletta, Z. Bisoffi, 

R. Visonà, G. Gaiera, G. Gregis, L. Tomasoni, 

F. De Iaco, F. Castelli – Lombardy Study Group 

on International Health (SIRL) 

O297 Retrospective study of imported malaria 

15:54 diagnosed in Mallorca, Spain 

M. Rotger, C. Lloret, T. Serra, S. Pons, 

M.A. Vicente, A. de Lucio, J.L. Perez 

(Palma de Mallorca, Madrid, E) 

O298 Ultrasound guided fine needle aspiration 

16:06 biopsy in the diagnosis of visceral leishmaniasis 

A. Giorgio, G. de Stefano, V. Scala, G. Liorre, 

A. Di Sarno, A. Sullo, P. Sorrentino (Naples, I) 

O299 Short-course liposomal amphotericin B in the 

16:18 treatment of infantile visceral leishmaniasis: 

the Italian experience 

A. Cascio, L. di Martino, P. Occorsio, R. Giacchino, 

S. Catania, A.R. Gigliotti, C. Aiassa, C. Iaria, 

S. Giordano, C. Colomba, V. Frasca Polara, 

L. Titone, L. Gradoni, M. Gramiccia, S. Antinori 

(Messina, Naples, Genoa, Rome, Palermo, Milan, I) 

O300 An open, randomised controlled trial of 

16:30 penicillin, doxycycline, and cefotaxime in 

patients with severe leptospirosis 

Y. Suputtamongkol, K. Niwatayakul, C. Suttinont, 

K. Losuwanaluk, R. Limpaiboon, W. Chierakul, 

V. Wuthiekanun, S. Triengrim, M. Chenchitikul, 

N. White (Bangkok, Loei Province, Nakhon 

Ratchasima Province, Bureerum Province, 

Udornthani Province, Nondhaburi, TH) 

O301 A study on some epidemiologic and 

16:42 paediatric aspects of toxocarosis in Hungary 

Z. Szénási, O. Bede, J. Danka, K.N. Horváth, 

I. Kucsera, É. Fok, E. Orosz 

(Budapest, Szeged, HUN) 

O302 Serological evidence for the occurrence of 

16:54 tick-borne diseases in northern Mongolia 

G. Walder, E. Lkhamsuren, D. Abmed, 

T. Batmunkh, D. Orth, M.P. Dierich, R. Würzner, 

G. Heinz (Innsbruck, A; Ulan Bataar, MN; 

Moscow, RUS; Vienna, A) 

O303 The United Kingdom National External 

17:06 Quality Assessment Scheme for Parasitology: 

toxoplasma subschemes 

M. Kettelhut, P. Chiodini, D. Ho-Yen, R. Holliman, 

V. James, P. Thomas (London, Inverness, 

Swansea, UK) 

O304 Web-based guidelines for the evaluation of 

17:18 fever in returning travellers and migrants 

(www.fevertravel.ch): promotion and 

appropriateness for the primary care 

physician 

V. D'Acremont, A. Ambresin, B. Burnand, 

B. Genton (Lausanne, CH) 


DIAGNOSIS OF TB AND ATYPICAL PNEUMONIA INFECTIONS IN AN ENLARGED EUROPE: 

THE NEED FOR FAST AND STANDARDIZED METHODS 

INTEGRATED SYMPOSIUM 

MONDAY 3RD MAY, 15.30 – 17.30, HALL V 

Chairpersons: 

Dr. Sabine Rüsch-Gerdes (Germany) 

Dr. Salman Siddiqi (USA) 

n Modern laboratory diagnosis of tuberculosis infection, 

clinical disease and drug resistance in Europe and beyond 

Prof. Francis Drobniewski, 

Mycobacterium Reference Unit, Dulwich Hospital, London, UK 

n Susceptibility testing of Mycobacterium tuberculosis 

against second line drugs: a practical approach 

Dr. Sabine Rüsch-Gerdes, 

Borstel TB Reference Center, Germany 

n Detection of Mycobacterium tuberculosis from clinical 

specimens using molecular methods: experiences from 

a reference laboratory with real-time SDA 

Prof. Massimo Clementi, 

Ospedale S. Raffaele, Milano, Italy 

n Diagnosis of Atypical Pneumonia: the role of NAATs 

and performance of a new assay using SDA technology 

Dr. Berndt Claesson, 

Kärnsjukhuset, Skövde, Sweden BD, BD logo and all other trademarks are the property of Becton, Dickinson and Company. ©2004 BD. Link-to-Business. 

The new standards for 

tuberculosis diagnostics 

n BD Bactec MGIT 960 

n BD ProbeTec ET 

For more information, 

please go to our website: 

www.bd.com/diagnostics 

BD Diagnostics

Meeting 

Hall I 



Rational antibiotic use: the future of lower 

respiratory tract infection (LRTI) treatment 

Chairpersons: Michael Niederman (Mineola, USA) 

Hartmut Lode (Berlin, D) 

S305 Welcome and opening remarks 

15:30 Michael Niederman (Mineola, USA) 

S305 New options for the treatment of hospitalised 

15:35 community-acquired pneumonia 

Michael Tamm (Basle, CH) 

S306 Differentiation of antibiotics for LRTIs 

16:00 Guy Amsden (Cooperstown, USA) 

S307 Antibiotic therapy for acute exacerbation of 

16:25 chronic bronchitis 

Francesco Blasi (Milan, I) 

S308 Clinical relevance of in vitro antibiotic 

16:50 resistance 

Michael Niederman (Mineola, USA) 



Hartmut Lode (Berlin, D) 

Club A 


Novel advances in antifungal therapy 

Chairpersons: Ben de Pauw (Nijmegen, NL) 

Raoul Herbrecht (Strasbourg, F) 


Ben de Pauw (Nijmegen, NL) 

S309 The relevance of pharmacokinetics in the 

15:40 treatment of fungal infections 

David Andes (Madison, USA) 

S310 Emerging epidemiology of fungal infections 

16:05 Francesco Menichetti (Pisa, I) 

S311 Anidulafungin: a new echinocandin and its 

16:30 role in the management of invasive Candida 

infections 

Peter Pappas (Birmingham, USA) 

S312 Contemporary therapy approaches for 

16:55 invasive aspergillosis 

Raoul Herbrecht (Strasbourg, F) 



Vicuron Pharmaceuticals 

Meeting 

Hall V 

Diagnosis of tuberculosis and atypical 

pneumonia infections in an enlarged Europe: 

the need for fast and standardised methods 

Chairpersons: Sabine Rüsch-Gerdes (Borstel, D) 

Saman Siddiqi (Baltimore, USA) 

S313 Modern laboratory diagnosis of tuberculosis 

15:30 infection, clinical disease and drug resistance 

in Europe and beyond 

Francis Drobniewski (London, UK) 

S314 Susceptibility testing of Mycobacterium 

16:00 tuberculosis against second line drugs: 

a practical approach 

Sabine Rüsch-Gerdes (Borstel, D) 

S315 Detection of Mycobacterium tuberculosis 

16:30 from clinical specimens using molecular 

methods: experiences from a reference 

laboratory with real-time strand displacement 

amplification (SDA) 

Massimo Clementi (Milan, I) 

S316 Diagnosis of atypical pneumonia: the role of 

17:00 NAATs and performance of a new assay using 

SDA technology 

Berndt Claesson (Skövde, S) 

Integrated symposium arranged by BD 


Scientific Programme Tuesday, May 4, 2004 


Small Hall How to prepare and deliver scientific 

E317 communication effectively? 

07:15 Experts: Ethan Rubinstein (Tel-Hashomer, IL) 

Achim Schwenk (London, UK) 

Objectives: 

To discuss how to prepare and communicate: 

Do I have a novel message? 

What ingredients are novel? 

Is my message novel and important? 

Who will be my readership/ audience? 

What consequences do I expect from my 

message (publication, collaboration, 

preparation for grant submission, etc? 

Will it satisfy the most rigorous reviewer? 

To discuss how to deliver a communication: 

How do I make a preliminary plan for the 

introduction, material and methods, results 

and most important discussion? 

What is the content of each section? 

How do I construct the discussion, and put the 

results into prospective? 

Club A New developments in the diagnosis of 

invasive mycoses 

E318 Experts: Olivier Lortholary (Paris, F) 

07:15 Jacques Bille (Lausanne, CH) 

Objectives: 

To critically assess the value, limits, pitfalls and 

clinical benefit of new diagnostic approaches 

(antigenic and molecular) of selected invasive 

mycoses, using clinical examples. 

Meeting MDR tuberculosis: risk factors and 

Hall IV management 

E319 Experts: Serguei Popov (Moscow, RUS) 

07:15 Francis Drobniewski (London, UK) 

Objectives: 

To understand the scale of MDRTB in the 

world today; the main reasons for the 

development of MDR TB; the professional 

and hospital cross-infection risks of MDRTB; 

the clinical and social management of MDRTB. 

To discuss implementation of effective MDR 

TB Control Programmes. 


Meeting Cost-effective use of the clinical microbiology 

Hall V laboratory 

E320 Experts: Barth Reller (Durham, USA) 

07:15 Vincent Jarlier (Paris, F) 

Objectives: 

To critically assess the traditional and new 

diagnostic methods for their cost-effectivness, 

and clinical relevance 

Chamber Clonal analysis of bacterial populations 

Hall Experts: Mark Achtman (Berlin, D) 

E321 Ed Feil (Bath, UK) 

07:15 

Objectives: 

To discuss what are the advantages (and 

disadvantages) of MLST over other methods. 

To examine how these approaches are 

validated for phylogenetic analysis? 

To examine if alternative approaches exist. 

To understand how bacterial infection and 

aid our understanding of epidemic spread, 

the distribution of virulence factors and 

antibiotic resistance. 

Conference Diagnosis and management of chronic Lyme 

Hall 

disease 

E322 Experts: Gary Wormser (New York, USA) 

07:15 Franc Strle (Ljubliana, SI) 

Objectives: 

To discuss diagnostic modalities, treatment 

and long-term outcome of Lyme borreliosis.

Meeting 

Hall I 

Keynote Lectures 


Meningococcal infection: still a challenge in 

the 21 st century 

Chairperson: Jarmila Jelinkova (Prague, CZ) 

K323 Paula Kriz (Prague, CZ) 

08:30 

Forum 

Hall 

Evolutionary engineering of antibiotic 

resistance 

Chairperson: Giuseppe Cornaglia (Verona, I) 

K324 Fernando Baquero (Madrid, E) 

08:30 

Small 

Hall 


Cancer and infection: a two-way road 

Chairpersons: Murat Akova (Ankara, TR) 

Hans Hirsch (Basle, CH) 

S325 Epstein-Barr virus and lymphoproliferative 

10:00 disorders 

Manlio Ferrarini (Genoa, I) 

S326 Polyomavirus BK: role of persisting 

10:30 replication for organ involvement and 

malignant transformation in transplant 

patients 

Hans Hirsch (Basle, CH) 

S327 Hepatitis B and C viruses in liver carcinogenesis 

11:00 Massimo Levrero (Rome, I) 

S328 Tuberculosis and stem cell transplantation 

11:30 Hamdi Akan (Ankara, TR) 

Joint symposium arranged with the European 

Organisation for Research and Treatment of 

Cancer, International Antimicrobial Therapy Group 

(EORTC-IATG) 

Panorama 

Hall 

Vector-transmitted diseases in the tropics 

Chairpersons: Maria Guzman (Havana, CU) 

Tomas Jelinek (Berlin, D) 

S329 Dengue, the pandemic and its clinical 

10:00 consequences 

Maria Guzman (Havana, CU) 

S330 Epidemiology of imported malaria in Europe 

10:30 Tomas Jelinek (Berlin, D) 

S331 Filarial infections – a risk for travellers? 

11:00 Christoph Hatz (Basle, CH) 

S332 Leishmaniasis, imported and autochthonous 

11:30 Jorge Alvar (Madrid, E) 

Forum 

Hall 

The clinical relevance of rapid diagnostics 

Chairpersons: Margareta Ieven (Edegem, B) 

Anton van Loon (Utrecht, NL) 

S333 Point-of-care testing in bacteriology – 

10:00 uses and limitations 

Barth Reller (Durham, USA) 

S334 Real-time PCR detection of group B 

10:30 streptococci (GBS) in less than one hour: 

a clinical revolution 

Michael G. Bergeron (Québec City, CAN) 

S335 Rapid detection of respiratory viruses: 

11:00 when and how? 

Margareta Ieven (Edegem, B) 

S336 Cost-effectiveness of real-time PCR for 

11:30 respiratory viruses in patients hospitalised 

with lower respiratory tract infection 

Anton M. van Loon (Utrecht, NL) 


Study Group on Molecular Diagnostics (ESGMD) 


Meeting 

Hall IV 


The international dimension of 

epidemiological typing 

Chairpersons: Alex van Belkum (Leiden, NL) 

Marek Gniadkowski (Warsaw, PL) 

S337 The easy visualisation of clones from 

10:00 multilocus sequence typing data 

Ed Feil (Bath, UK) 

S338 Genetic portraits of methicillin-resistant 

10:24 Staphylococcus aureus clones in hospitals 

and in the community 

Marta Aires de Sousa (Oeiras, P) 

S339 Review of MDR tuberculosis in Russia 

10:48 Serguei Popov (Moscow, RUS) 

S340 Dissemination of antimicrobial resistance in 

11:12 the nosocomial environment 

Marek Gniadkowski (Warsaw, PL) 

S341 Microbial surveillance of diphtheria across 

11:36 Europe 

Androulla Efstratiou (London, UK) 

South 

Hall 


Study Group on Epidemiological Markers (ESGEM) 

Auditing antimicrobial prescriptions in Europe 



S342 Audit Project Odense for General Practice 

10:00 Kirsten Schaefer (Roskilde, DK) 

S343 Antibiotic prescribing in the primary 

10:30 paediatric care in central eastern Europe – 

common history with different approaches 


S344 Antibiotic prophylaxis in surgery: 

11:00 the Dutch experience 

Inge Gyssens (Rotterdam, NL) 

S345 Antibiotic prescribing practices and policies in 

11:30 intensive care units 

Dominique L. Monnet (Copenhagen, DK) 


Study Group on Antibiotic Policies (ESGAP) 


Club A 

Oral Sessions 

Antibiotic resistance: from ESBL to 

fluoroquinolones 

Chairpersons: Luisa Peixe (Porto, P) 


O346 EARSS report on increasing fluoroquinolone 

10:00 resistance among Escherichia coli in Europe 

H. Grundmann, P. Schrijnemakers, N. Bruinsma, 

E. Tiemersma, J. Monen, J.E. Degener, 

G. Cornaglia and EARSS participants 

O347 First detection of the transferable quinolone 

10:12 resistance determinant in clinical Providencia 

stuartii strains in Egypt 

I. Wiegand, N. Khalaf, M.H.M. Al-Agamy, 

B. Wiedemann (Bonn, D; Cairo, EGY) 

O348 Fluoroquinolone consumption and 

10:24 fluoroquinolone resistance in haematologyoncology 

patients – Ecological analysis in two 

university hospitals, 1999–2002 

W.V. Kern, K. de With, C. Gonnermann, E. Strehl, 

M. Steib-Bauert, S. Reuter, H. Bertz, U. Frank, 

H. von Baum (Freiburg, Ulm, D) 

O349 Genetic analysis of emerging fluoroquinolone- 

10:36 resistant Escherichia coli in Indonesia 

K. Kuntaman, E.S. Lestari, J. Severin, 

N.M. Mertaniasih, M. Purwanta, A. van Belkum, 

H.A. Verbrugh on behalf of the Antimicrobial 

Resistance in Indonesia (AMRIN) study group 

O350 Outpatient use of fluoroquinolones in Europe 

10:48 with focus on respiratory tract infections 

H. Goossens, K. Dirven, M. Ferech 

the ESAC Project Group 

O351 Extended-spectrum beta-lactamases from 

11:00 the community and hospital environments 

in Portugal: dissemination of TEM-24 

E. aerogenes European epidemic clone and 

emergence of CTX-M enzymes 

E. Machado, R. Cantón, A. Rollán, J.C. Sousa, 

F. Baquero, T.M. Coque, L. Peixe 

(Porto, P; Madrid, E) 

O352 Isolation of extended-spectrum beta- 

11:12 lactamase producing Enterobacteriaceae from 

community-based patients in the United 

Kingdom 

F. M'Zali, J. Dave, S. Ager, M. Denton 

(Leeds, UK) 

O353 Characterisation of a new integron carrying a 

11:24 metallo-beta-lactamase and a carbenicillinase 

from Pseudomonas aeruginosa 

S.M. Quinteira, J.C. Sousa, L. Peixe 

(VN Famalicão, Porto, P)


O354 Epidemiology and clinical features of 

11:36 bacteraemia due to extended-spectrum 

betalactamase-producing Escherichia coli 

J. Rodríguez-Bano, M.D. Navarro, L. Romero, 

M.A. Muniain, L. Martínez-Martínez, 

R. Pérez-Cano, E.J. Perea, A. Pascual (Seville, E) 

O355 The first report of a metallo-beta-lactamase- 

11:48 producing Proteus mirabilis clinical isolate 

from Greece 

I. Galani, M. Souli, Z. Chryssouli, D. Katsala, 

H. Giamarellou (Chaidari, GR) 

Chamber 

Hall 

Hepatitis 

Chairpersons: Massimo Clementi (Milan, I) 

Pavel Chalupa (Brno, CZ) 

O356 HCV core, F, NS3, NS4B and NS5A are the 

10:00 major immunogenic proteins in humoral 

immunity in chronic HCV infection 

K. Melen, M. Sillanpää, P. Keskinen, 

M. Lappalainen, I. Julkunen (Helsinki, FIN) 

O357 Comparative analysis of intra-hepatic mRNA 

10:12 levels for IFNs and IFN-related genes in HCV 

mono-infected and in HCV/HIV co-infected 

patients 

I. Abbate, G. Cappiello, S. Rosati, G. Tocci, 

G. Antonucci, M. Solmone, R. Longo, A. Spanò, 

M.R. Capobianchi (Rome, I) 

O358 Sustained response to interferon-ribavirin 

10:24 combination therapy in chronic hepatitis C 

predicted by a model of viral dynamics using 

both HCV-RNA and alanine amino transferase 

P. Colombatto, L. Civitano, P. Ciccorossi, 

F. Oliveri, B. Coco, D. Flichman, R. Sacco, 

M. Campa, F. Bonino, M.R. Brunetto (Pisa, Milan, I) 

O359 Treatment of acute C hepatitis with pegylated 

10:36 interferon alpha-2b: preliminary results 

G. Cariti, F.G. De Rosa, S. Quaglia, I. Meoli, 

L. Veronese, S. Audagnotto, T. De Blasi, 

O. Bargiacchi, M. Bonasso, R. Raiteri, G. Di Perri 

(Turin, I) 

O360 Mutation analysis of ISDR and V3 domains of 

10:48 hepatitis C virus NS5A region during interferon 

therapy with or without ribavirin 

P. Veillon, C. Payan, F. Lunel-Fabiani 

and the Fontevraud Study Group 

O361 A nosocomial hepatitis B outbreak in Danish 

11:00 children 

N. Fisker, N.L.T. Carlsen, H.-J. Kolmos, 

L. Tønning-Sørensen, A. Høst, P.B. Christensen 

(Odense, DK) 

O362 Flares of hepatitis, circulating hepatitis B core 

11:12 (HBc)-specific T cells, and sustained virologic 

response to antiviral therapy in chronic 

hepatitis B patients 

P. Carotenuto, O. Pontesilli, A. Artsen, 

M. van Zonneveld, H. Janssen, H. Niesters, 

A. Osterhaus (Rotterdam, NL) 

O363 A new model of HBV infection dynamics 

11:24 shows a multiphasic decay of viral load and a 

short half-life of circulating virus in anti-HBe 

positive patients treated with lamivudine 

L. Civitano, P. Colombatto, R. Bizzarri, 

D. Flichman, F. Oliveri, P. Ciccorossi, B. Coco, 

R. Sacco, F. Bonino, M.R. Brunetto (Pisa, Milan, I) 

O364 Control of hepatitis A outbreaks before and 

11:36 after the era of routine childhood hepatitis A 

vaccination 

C. Stein-Zamir, I. Volovik, S. Rishpon 

(Jerusalem, Haifa, IL) 

O365 20 years hepatitis A sero-epidemiology in 

11:48 Belgium 

R. Vranckx (Brussels, B) 

Conference 

Hall 

Epidemiology and management of 

community-acquired pneumonia 

Chairpersons: Herman Goossens (Antwerp, B) 


O366 Epidemiology of community-acquired 

10:00 pneumonia in Belgium 

M. Ieven, K. Dirven, K. Loens, D. Ursi, T. Beck, 

H. Wouters, H. Goossens (Wilrijk, B) 

O367 Value of real-time PCR for the aetiologic 

10:12 diagnosis in adults hospitalised with lower 

respiratory tract infections 

J.J. Oosterheert, A. van Loon, R. Schuurman, 

G. Nossent, A. Hoepelman, M. Bonten (Utrecht, NL) 

O368 Significance of bronchoscopy and invasive 

10:24 techniques in the diagnosis of communityacquired 

pneumonia 

E. Manali, A. Papadopoulos, K. Kanellakopoulou, 

M. Tsivra, V. Polychronopoulos, H. Giamarellou 

(Athens, GR) 

O369 Diversity of Legionella subtypes in cooling 

10:36 towers. Why only one environmental strain 

causes the clinical cases 

S. Ragull, M. Garcia-Nuñez, E. Junyent, 

M.L. Pedro-Botet, N. Sopena, A. Dominguez, 

M. Sabria - Grupo de Estudio de la Legionelosis 



O370 Current clinical outcomes in hospitalised 

10:48 patients with community-acquired Legionella 

pneumonia 

A. Mykietiuk, J. Carratalà, N. Fernández-Sabé, 

R. Verdaguer, J. Dorca, F. Manresa, F. Gudiol 

(L´Hospitalet de Llobregat, E) 

O371 Outbreak of pneumococcal pneumonia in a 

11:00 retirement home in France in 2003 

Y. Hansmann, A. Doyle, O. Lesens, 

A. Perrocheau, B. Jaulhac, V. Murbach, V. Remy, 

D. Christmann (Strasbourg, Paris, F) 

O372 Early administration of antibiotics in patients 

11:12 with community-acquired pneumonia in the 

emergency room 

E. Coma, J. Solis, G. Vidal, C. Ferré, J. Alba, C. Agusti, 

J.M. Guardiola, M. Gurgui, G. Vazquez-Mata 

S.C.M.U.-A.C.M.E.S. – Pneumocom2 Study Group 

O373 Treatment with sequential intravenous/oral 

11:24 moxifloxacin was associated with faster 

clinical improvement and earlier discharge 

from hospital in CAP patients requiring initial 

parenteral therapy compared to standard 

therapy 

T. Welte, T. Bauer for the MOXIRAPID study group 

O374 Management of community-acquired lower 

11:36 respiratory tract infections in the emergency 

department. A prospective 2-year observational 

study in over 170 centres throughout 

France 

D. Elkharrat, P. Gerbaux, C. Ginzburg, 

M.C. Grossin, C. Leroux, N. Peschansky, 

M. Herad, J. Imperatori 

and the French LRTI network RESAU 

O375 Recently formulated guidelines for empiric 

11:48 therapy of community-acquired pneumonia 

increase antibiotic use by 63% 

J.J. Oosterheert, M. Bonten, M. Schneider, 

A. Hoepelman (Utrecht, NL) 


Meeting 

Hall I 


Clinical implications of early antifungal 

therapy – getting it right the first time 

Chairpersons: Bart-Jan Kullberg (Nijmegen, NL) 

Jack Sobel (Detroit, USA) 

10:00 Welcome and opening remarks 

Bart-Jan Kullberg (Nijmegen, NL) 

S376 Early diagnosis of fungal infections 

10:05 Georg Maschmeyer (Berlin, D) 

S377 Impact of early antifungal therapy 

10:25 Tania Sorrell (Sydney, AUS) 

S378 Advances in the treatment of invasive mould 


Olivier Lortholary (Paris, F) 

S379 Developments in the management of 

11:05 yeast infections 


S379A New options for the treatment of candidemia 

11:25 Bart-Jan Kullberg (Nijmegen, NL) 




Meeting 

Hall V 


Influence of the regulatory environment on 

antimicrobial resistance 

Chairpersons: Roger Finch (Nottingham, UK) 

Eddie Power (West Haven, USA) 

S380 Antimicrobial resistance and drug selection 

10:00 Alasdair MacGowan (Bristol, UK) 

S381 The clinical implications of appropriate 

10:30 antimicrobial selection 

Javier Garau (Barcelona, E) 

S382 Influence of the regulatory environment on 

11:00 the antimicrobial marketplace 

Ragnar Norrby (Stockholm, S) 

S383 Implications of regulatory restrictions 

11:30 Eddie Power (West Haven, USA) 


Bayer Healthcare

Poster Session V 

Topics Session V 



– Infectious diseases and public 

health issues 

★ P1401–P1430 

– Infection in the immunocompromised 

HIV-negative host 

P1431–P1454 

– Antimicrobial resistance mechanisms – II P1455–P1477 

– Mycobacterial diagnosis P1478–P1495 

– Mycobacterial infection: epidemiology P1496–P1512 

– Nosocomial infections: II 

● P1513–P1539 

– Ventilator-associated pneumonia 

● P1540–P1551 


nonfermentative Gram-negative bacilli – II 

● P1552–P1564 

– Hepatitis C P1565–P1582 

– Sexually transmitted diseases P1583–P1612 

– Diagnostic methods: 

antibiotic susceptibility 

■ P1613–P1630 

– Diagnostic methods: serology 

■ P1631–P1647 

– Diagnostic methods: blood culture 

■ P1648–P1661 

12:15–13:00 

Guided Poster Walks Session V 

Theme: Infectious diseases and public health issues 

Chairpersons: Carol Joseph (London, UK) 

Maria G. Guzman (Havana, CU) 



Theme: Nosocomial infections 

Chairperson: Barry Coockson (London, UK) 



Theme: Diagnostic methods 

Chairperson: Anton Van Loon (Utrecht, NL) 


Posters selected from within the topics marked ■ 

For further details on the above poster sessions see pages 120–147 

Poster Session VI 

Topics Session VI 


– Community-acquired infections 

★ P1662–P1701 

– Quinolones in vitro studies P1702–P1713 

– Antimicrobial resistance mechanisms – III P1714–P1739 


Gram-positive bacteria 

P1740–P1762 

– Mycology P1763–P1791 

– Progress in pharmacokinetics and 

pharmacodynamics- II 

● P1792–P1820 


streptococcus, meningococcus and 

haemophilus 

P1821–P1840 

– Emerging infectious diseases P1841–P1861 

– ESBL and metallo-beta-lactamases – II ■ P1862–P1881 

– Susceptibility to miscellaneous 

antimicrobial agents 

P1882–P1896 

13:00–13:45 

Guided Poster Walks Session VI 

Theme: Community-acquired infections 

Chairpersons: Michel Glauser (Lausanne, CH) 

Ethan Rubinstein (Tel Hashomer, IL) 



Theme: Pharmacokinetics 

Chairpersons: H. Derendorf (Gainsville, USA) 

Paul Tulkens (Brussel, B) 



Theme: ESBL and metallo-beta-lactamases 

Chairperson: David Livermore (London, UK) 


Posters selected from within the topic marked ■ 


Small 

Hall 


Biofilms 


Chairpersons: Miroslav Votava (Brno, CZ) 

Niels Høiby (Copenhagen, DK) 

S384 Biofilm biology – role of quorum sensing 

14:00 Leo Eberl (Zurich, CH) 

S385 The impact of growth as a biofilm upon 

14:30 antibiotic susceptibilities 

Peter Gilbert (Manchester, UK) 

S386 Biofilm and fungi 

15:00 Mahmoud A. Ghannoum (Cleveland, USA) 

S387 Biofilm in respiratory tract disease 

15:30 Niels Høiby (Copenhagen, DK) 

Panorama 

Hall 

Current problems in clinical mycology 

Chairpersons: Maiken Arendrup (Copenhagen, DK) 

Jacques Bille (Lausanne, CH) 

S388 Mucormycosis: Pathogenesis, diagnosis, 

14:00 management 

Andreas H. Groll (Munster, D) 

S389 Mycotic bone infections, diagnosis and 

14:30 treatment 

Olivier Lortholary (Paris, F) 

S390 CNS fungal infections: epidemiology and 

15:00 management 

Emmanuel Roilides (Thessalonica, GR) 

S391 Fungal endocarditis 

15:30 Ethan Rubinstein (Tel Hashomer, IL) 

Meeting 

Hall I 

Official symposium arranged with the ESCMID 

Fungal Infections Study Group (EFISG) 

Antimicrobial susceptibility testing of difficult 

organisms 

Chairpersons: Juan Luis Rodriguez-Tudela 

(Majadahonda, E) 

Gunnar Kahlmeter (Växjö, S) 

S392 Fungi 

14:00 Juan Luis Rodriguez-Tudela (Majadahonda, E) 

S393 Mycobacteria 

14:30 Francis Drobniewski (London, UK) 

S394 Chlamydia and Mycoplasma 

15:00 Christiane Bébéar, (Bordeaux, F) 

S395 Viruses 

15:30 Bo Svennerholm (Gothenburg, S) 


Meeting 

Hall IV 

Tick-borne encephalitis 

Chairpersons: Milan Labuda (Bratislava, SK) 

Antti Vaheri (Helsinki, FIN) 

S396 Epidemiology and ecology of tick-borne 

14:00 encephalitis 

Milan Labuda (Bratislava, SK) 

S397 Clinical manifestations and sequelae of 

14:30 tick-borne encephalitis 

Mats E. Haglund (Kalmar, S) 

S398 Current and future possibilities for prevention 

15:00 of tick-borne encephalitis 

Jiri Beran (Hradec Králové, CZ) 

S399 Containment of TBE: the Austrian experience 

15:30 Christian Kunz (Vienna, A) 

Meeting 

Hall V 

Oral Sessions 

In vitro studies of antimicrobial agents, 

fitness & virulence factors of bacteria 

Chairpersons: Uwe Frank (Freiburg, D) 

Ferenc Rozgonyi (Budapest, HUN) 

O400 Sensititre YeastOneTM Colorimetric 

14:00 Antifungal Plate for testing voriconazole 

against isolates of Candida species: 

a comparison with the NCCLS M27-A2 

microdilution reference method 

A. Espinel-Ingroff, S. Killian, C. Knapp, N. Holliday 

(Richmond, Westlake, USA) 

O401 Susceptibility of Aspergillus fumigatus to 

14:12 voriconazole by flow cytometry 

R. Araújo, A. Gonçalves Rodrigues, C. Pina-Vaz 

(Porto, P) 

O402 In vitro activity of novispirins-antimicrobial 

14:24 peptides with broad spectrum activity 

P.-H. Mygind, C.-P. Sonksen, D. Raventos, 

O. Taboureau, B. Weber, J. Lin, S. Otani, 

D.-S. Yaver, H.-H. Kristensen 

(Bagsvaerd, DK; Davis, USA) 

O403 Study of the impact of macrolides against 

14:36 Pseudomonas aeruginosa cystic fibrosis 

isolates grown as biofilm 

A. Dubouix, L. Vaugien, C. Andrieu, S. Barthet, 

J. Grimoud, C. Roques, N. Marty (Toulouse, F) 

O404 Comparison of the mutant prevention 

14:48 concentration of gatifloxacin, garenoxacin, 

gemifloxacin, levofloxacin and moxifloxacin 

against clinical isolates of Streptococcus 

pneumoniae collected prior to (1994–97) and 

after 1997 (1997–2003) 

J. Blondeau, K. Metzler, P. Hedlin, G. Hansen, 

K. Drlica (Saskatoon, CAN; Newark, USA)


O405 Virulence factors of ciprofloxacin-resistant 

15:00 Escherichia coli in intensive care units 

D. Jonas, F. Garcia, D. Hartung, F. Daschner 

(Freiburg, D; San José, CR) 

O406 In vitro and in vivo fitness cost of antibiotic 

15:12 resistance in Escherichia coli 

V.I. Enne, A.A. Delsol, G.R. Davis, J.M. Roe, 

P.M. Bennett (Bristol, UK) 

O407 Fitness cost of sul2-coding plasmids in 

15:24 Escherichia coli 

V.I. Enne, P.M. Bennett, D.M. Livermore, 

L.M.C. Hall (Bristol, London, UK) 

O408 High prevalence and combinations of 

15:36 antimicrobial resistance traits in commensal 

bacteria from a very remote rural community 

of Alto Amazonas (Peru) 

A. Mantella, H. Rodriguez Ferrucci, C. Fernandez 

Neyra, M. Benedetti, L. Pallecchi, M. Strohmeyer, 

F. Bartalesi, C. Kristiansson, T. Falkenberg, 

E. Gotuzzo, A. Bartoloni, G.M. Rossolini, F. Paradisi 

(Florence, I; Yurimaguas, PE; Siena, I; 

Stockholm, S; Lima, PE) 

O409 Bacterial fitness of drug-resistant 

15:48 Pseudomonas aeruginosa 

S. Frank, U. Frank, F. Daschner (Freiburg, D) 

Chamber 

Hall 

Mycobacterial infections: diagnosis and 

epidemiology 

Chairpersons: Josef Scharfen (Trutnov, CZ) 

Pernille Ravn (Hvidovre, DK) 

O410 Increased expression of adhesion molecules 

14:00 on peripheral blood monocytes in patients 

with severe pulmonary tuberculosis 

M. Ioanas, A. Riecks, M.W.R. Pletz, H. Lode, 

T. Schaberg (Berlin, D; Atlanta, USA; Rotenburg, D) 

O411 The diagnostic potential of the QuantiFERON- 

14:12 RD1 test in patients with active tuberculosis 

P. Ravn, M. Munk, Å.B. Andersen, B. Lundgren, 

J. Lundgren, L.N. Nielsen, A.K. Jensen, P. Andersen, 

K. Weldingh (Copenhagen, Hvidovre, DK) 

O412 The role of a new immune diagnostic test 

14:24 based on ESAT-6 epitopes in the evaluation 

of subjects with a clinical suspicion of active 

tuberculosis 

D. Goletti, S. Carrara, D. Vincenti, F. Palmieri, 

A. Rianda, M. Bocchino, C. Saltini, N. Petrosillo, 

M. Amicosante, E. Girardi (Rome, I) 

O413 Evaluation of a new automated, rapid, 

14:36 colorimetric culture system using solid 

medium for laboratory diagnosis of 

tuberculosis and determination of 

antituberculosis drug susceptibility 

O. Baylan, O. Kisa, A. Albay, L. Doganci 

(Ankara, TR) 

O414 Quality assurance in molecular diagnosis of 

14:48 tuberculosis 

A. Flountzi, D. Houhoula, A. Priftis, N.J. Legakis, 

L. Zerva (Athens, GR) 

O415 Molecular characterisation of Mycobacterium 

15:00 tuberculosis strains from southern Ukraine: 

evidence of drug resistance rates and Beijing 

strains prevalence 

V. Nykolayevskyy, T. Brown, Y. Bazhora, 

A. Asmolov, N. Levitskaya, F. Drobniewski 

(Odessa, UKR; London, UK) 

O416 Repetitive element typing of M. tuberculosis 

15:12 from the Caribbean and African population in 

the UK reveals unsuspected transmission 

J.M. Greig, J.T. Evans, E.G. Smith, J.A. Innes, 

P.M. Hawkey (Birmingham, UK) 

O417 Clinical and social profile of TB patients in 

15:24 civilian and penitentiary sectors in Samara, 

Russia 

Y. Balabanova, M. Ruddy, C. Graham, I. Fedorin, 

S. Kuznetsov, A. Melentyev, S. Zakharova, 

N. Malomanova, E. Elizarova, V. Nikolayevskyy, 

F. Drobniewski (London, UK; Samara, RUS; 

Odessa, UKR) 

O418 Clinical presentation and outcome of 

15:36 HIV-associated tuberculosis in the HAART 

era in Rome 

N. Petrosillo, A. Rianda, D. Goletti, E. Girardi, 

P. De Mori, E. Busi Rizzi, R. Urso, M. De Marco, 

R. Maddaluno, F. Palmieri for “Tuberculosis- 

I.N.M.I. L.Spallanzani Study Group” 

O419 Treatment of tuberculosis in HIV-infected 

15:48 patients 

A. Matteelli, C. Casalini, A.-C. Carvalho, 

M. Manfrin, R. Poni Gore, N. Saleri, G. De Iaco, 

C. Pizzocolo, S. Capone, G. Carosi (Brescia, I) 



Conference 

Hall 

Infection in the immunocompromised host: 

diagnostic tools, treatment and monitoring 

O427 

15:24 

Lack of association between CMV-viraemia 

and bronchiolitis obliterans syndrome in lung 

transplant recipients 

Chairpersons: Matthew Falagas (Athens, GR) 

I.A. Forrest, A. Krause, P.A. Corris, J.H. Dark, 

Ben de Pauw (Nijmegen, NL) 

C.E. Taylor, F.K. Gould (Newcastle upon Tyne, UK) 

O420 A negative procalcitonin test as an indicator 

14:00 of non-infectious fever in neutropenic cancer 

patients with FUO 

O.J. Robinson, T. Calandra, F. Bally, M. Knaup, 

W. Beier, O. Marchetti 

(Lausanne, CH; Hennigsdorf, D) 

O421 Prevalence and impact of adenovirus viraemia 

14:12 in adult stem-cell transplant recipients 

treated with Campath-1H 

A. Geretti, E. Nieto, S. Ramalingam, A. Ho, 

M. Smith, G. Mufti, S. Devereux, A. Pagliuca, 

M. Zuckerman, D. Cubitt (London, UK) 

O422 Efficacy of caspofungin against invasive 

14:24 Candida or Aspergillus infections in 

neutropenic patients: review of the 

caspofungin database 

N. Kartsonis, H. Teppler, A. Taylor, R. Lupinacci, 

C. Sable (West Point, USA) 

O423 Impact of resolution of fever on the overall 

14:36 composite endpoint in a phase III study of 

caspofungin vs liposomal amphotericin B as 

empirical therapy for neutropenic patients 

with persistent fever 

B. de Pauw, C. Sable, T. Walsh, R. Lupinacci, 

M. Bourque, H. Teppler (Nijmegen, NL; 

West Point, Bethesda, USA) 

O424 Monitoring of Epstein-Barr virus (EBV) DNA 

14:48 load after haematopoietic stem cell transplantation 

for prevention, early diagnosis as well 

as antiviral and immune therapy of EBVassociated 

lymphoproliferative diseases 

A. Meerbach, B. Gruhn, R. Haefer, F. Zintl, 

P. Wutzler (Jena, D) 

O425 Real-time PCR quantification of EBV, CMV 

15:00 and HHV6 in patients after allogeneic 

haematopoietic stem cell transplantation 

P. Hubacek, O. Cinek, M. Zajac, S. Voslarova, 

P. Sedlakova, P. Keslova, J. Stary, P. Sedlacek 

(Prague, CZ) 

O426 Contamination of bone marrow products 

15:12 with a Mycobacterium mucogenicum-related 

pathogen 

I. Kassis, I. Oren, R. Finkelstein, G. Rabino, 

T. Katz, H. Sprecher (Haifa, IL) 


O428 Correlation between HHV8 infection and 

15:36 Kaposi’s sarcoma in a group of heart and lung 


B. Nocita, F. Poletti, B. Castiglioni, F. Farchi, 

S. Perrotta, M. Viganò, M. Andreoni, L. Minoli 

(Pavia, Rome, I) 

O429 Documented bacterial and fungal infections 

15:48 in orthotopic liver transplant recipients: 

an Italian multicentre study in 416 patients 

C. Viscoli, B. Bucci, M. Machetti, M. Spada, 

P. Amoroso, P. Burra, A. De Gasperi, G. Ferretti, 

G. Guaraldi, A. Pellizzari, E. Regalia, G. Sangiorgi, 

P. Toniutto, L. Boni (Genoa, Bergamo, Naples, 

Padua, Milan, Rome, Modena, Bologna, Udine, I)

Poster Sessions Sunday, May 2, 2004 

12:00–13:00 

Community-acquired infections: 

focus on unusual epidemics and update on 

S. pneumoniae 

P430 Community-acquired pneumonia caused by 

“atypical” pathogens: clinical discrimination 

with a predictive model and scoring system 

M. Masiá, F. Gutiérrez, J.C. Rodríguez, S. Padilla, 

G. Royo, J.M. Ramos, A. Ayelo, A. Martín-Hidalgo 

(Elche, Alicante, E) 

P431 Effects of a pneumococcal vaccination 

programme in adult invasive Streptococcus 

pneumoniae disease: a three-year experience 

F.J. Vasallo, A. González-Escalada, V. del Campo, 

S. Pérez, J. Torres (Vigo, E) 

P432 Effect of initial treatment on bacteraemic 

Streptococcus pneumoniae pneumonia 

(BSPP) mortality 

V. Pintado, R. Blazquez, E. Loza, J. Cobo, 

J. Fortun, E. Navas, C. Quereda, S. Moreno 

(Madrid, E) 

P433 Comparative, randomised, open, multicentre 

trial assessing the efficacy and safety of 

intravenous/oral azithromycin compared to 

intravenous/oral clarithromycin for the 

treatment of community-acquired pneumonia 

due to Legionella pneumophila 

J. Roig, M. Sabriá, J. Alegre, M. Gurgui, J.C. Checa – 

Spanish Study Group for Legionella 

P434 Pseudomonas aeruginosa as a risk factor in 

acute exacerbations of COPD 

M. Allewelt, S. Balk, H. Lode (Berlin, D) 

P435 Community outbreak of Legionella in 

Hospitalet (Spain). Usefulness of the 

epidemiological and molecular data to 

identify the source 

I. Barrabeig, M. Garcia-Nuñez, A. Dominguez, 

A. Rovira, S. Ragull, A. Pedrol, J.M. Elorza, 

M.L. Pedro-Botet, N. Sopena, M. Sabria 

(Barcelona, Badalona, E) 

P436 Significance of early Mycoplasma pneumoniae 

serodiagnosis in hospitalised patients with 


A. Kuhnke, M. Bender, M. Allewelt, A. Roth, 

H. Mauch, H. Lode (Berlin, D) 

P437 Prevalence and degree of Legionella 

colonisation in cooling towers 

M. Garcia-Nuñez, S. Ragull, E. Junyent, 

M.L. Pedro-Botet, N. Sopena, M. Sabria 

(Badalona, E) 

P438 Epidemiology of community-acquired 

pneumonia revisited: a large population-based 

prospective study in the Mediterranean coast 

of Spain 

F. Gutiérrez, M. Masiá, J.C. Rodríguez, S. Padilla, 

G. Royo, J.M. Ramos, A. Ayelo, A. Martín-Hidalgo 

(Elche, Alicante, E) 

P439 Factors influencing treatment outcome and 

length of stay in patients hospitalised for 


A. Neiss, D. Elkharrat, S. Kohno, J. Schentag, 

S. Decker-Burgard, K. Roscher 

(Munich, D; Paris, F; Nagasaki, JP; Buffalo, USA; 

Bad Soden am Taunus, D) 

P440 Bacteriological outcomes in hospitalised 

patients with community-acquired pneumonia 

treated with IV azithromycin plus ceftriaxone 

versus IV ceftriaxone plus clarithromycin or 

erythromycin 

M. Tamm, T. Todisco, P.A. Willcox, F. Carrillo, 

S. Fisher, P.J. de Caprariis, F. Blasi, I.M. Hoepelman 

(Basle, CH; Perugia, I; Cape Town, ZA; 

Guadalajara, E; New York, USA; Milan, I; 

Utrecht, NL) 

P441 First post-marketing data on treatment of 

community-acquired pneumonia with 

moxifloxacin i.v. 

J. Barth, H. Landen, K. Stauch 

(Halle/Saale, Leverkusen, D) 

P442 Atypical pathogens in pathogenesis of 

bronchial asthma in children and efficacy of 

azithromycin as a part of complex therapy 

O. Lasitsa, I. Ochotnicova, S. Lomonosov 

(Kyiv, UKR) 

P443 Management of community-acquired 

pneumonia in a hospital in Norway: 

penicillin still works! 

B. Waldum, A. Bucher (Oslo, N) 

P444 A case-control study on acute respiratory 

infections of patients in general practices in 

the Netherlands, October 2000 – September 

2003 

A.B. van Gageldonk-Lafeber, A. Bartelds, 

M-L.H. Heijnen, M. Peeters, S.M. van der Plas, 

S.C. de Greeff, B. Wilbrink 

(Bilthoven, Utrecht, Tilburg, NL) 

P445 Hospitalised community-acquired pneumonia: 

characteristics, aetiology and outcome 

É. Székely, C. Kósa, Z. Várnai, E. Ludwig 

(Budapest, HUN) 


page 65


P446 Comparison of additional antibacterial usage 

in patients with community-acquired 

pneumonia receiving telithromycin or 

clarithromycin: results from two double-blind, 

randomised clinical trials 

P.G. Davey, M. Niederman, J. Paladino, C. Taneja, 

G. Oster, J. Stewart, J. Chang 

(Dundee, UK; Mineola, Amherst, Brookline, USA; 

Quebec, CAN; Bridgewater, USA) 

P447 Seroprevalance of Chlamydophilia 

pneumoniae infection in patients with 

chronic stable asthma 

M. Aslan, K. Güven, G. Saglam, S. Altun, 

S. Saribas, B. Müsellim, B. Gemicioglu, 

B. Kocazeybek (Istanbul, TR) 

P448 Severe community-acquired pneumonia: 

impact of empirical antimicrobial treatment 

on outcome 

M. Daganou, P. Bakakos, A. Sakellaropoulos, 

M. Kompoti, A. Paridou, M. Ktena, A. Rassidakis 

(Athens, GR) 

P449 Efficacy of linezolid for the treatment of 

pneumonia caused by penicillin- (PRSP) or 

multi-drug resistant Streptococcus pneumoniae 

K. Tack, M. Ijzerman, R. Croos-Dabrera 

(Ann Arbor, USA) 

P450 Pathogenic role, epidemiology, and susceptibility 

to antimicrobial agents of Neisseria 

meningitidis isolated from lower respiratory 

tract secretions of adult patients 

E. Cercenado, B. Padilla, P. Martín-Rabadán, 

N. García-Escribano, O. Pérez-Olaso, E. Bouza 

(Madrid, E) 

P451 Efficacy of a 7-day course of oral telithromycin 

800 mg once daily in community-acquired 

pneumonia caused by resistant Streptococcus 

pneumoniae 

C. Fogarty, D. van Rensburg, C. de Salvo, 

M. Rangaraju, R. Nusrat (Spartanburg, USA; 

Witbank, ZA; Federal Capital, AR; Romainville, F; 

Bridgewater, USA) 

P452 Efficacy of telithromycin in patients with 

community-acquired respiratory tract 

infections caused by Streptococcus 

pneumoniae, including resistant strains 

C. Fogarty, P. Buchanan, M. Aubier, M. Baz, 

D. van Rensburg, M. Rangaraju, R. Nusrat 

(Spartanburg, Eugene, USA; Paris, F; Fresno, USA; 

Witbank, ZA; Romainville, F; Bridgewater, USA) 


P453 Epidemiology of hospitalised patients with 

AECB (acute exacerbation of chronic 

bronchitis) and Gram-negative bacilli in the 

sputum 

I. Gómez De Argila, C. Garcia Vidal, P. Almagro 

Mena, H. Monzón Camps, L. Cuadra Llompart, 

L. Canales, E. Cuchí, J. Garau (Terrassa, E) 

P454 Procalcitonin and neopterin correlates with 

aetiology and severity in adults with 

pneumonia 

C. Prat, J. Domínguez, J. Ruiz-Manzano, 

S. Blanco, R. Rivelo, F. Andreo, V Ausina 

(Badalona, E) 

P455 Rapid centrifugal method for Legionella 

antigen concentration in urine samples 

J. Domínguez, S. Blanco, C. Prat, R. Rivelo, 

M.D. Sánchez, M.A. Pallarés, V. Ausina 

(Badalona, E) 

P456 Usefulness of PORT-score to decide 

hospitalisation of patients with communityacquired 

pneumonia: analysis of 509 

consecutive patients classified in categories I 

and II 

C. Font, E. García-Vázquez, M. Cavalcanti, 

M. Camps, I. Aldabó, C. Esquinas, M.A. Marcos, 

J. Mensa, A. Torres, J. Puig (Barcelona, E) 

P457 Sputum color as marker for clinical success in 

patients with acute exacerbation of chronic 

bronchitis (AECB) treated with levofloxacin 

H. Lode, J. Eller, K. Roscher (Berlin, D) 

P458 Outcome and clinical differences between 

pneumococcal pneumonia with and without 

bacteraemia 

F. Jover, J.M. Cuadrado, L. Andreu, M. Rodríguez, 

R. Cañizares, S. Martinez, V. Ortiz, P. Roig 

(Alicante, E) 

P459 Comparative assessment of moxifloxacin and 

macrolides in acute exacerbation of chronic 

bronchitis: clinical efficacy and influence on 

the long-term prognosis 

S. Yakovlev, L. Dvoretsky, V. Nonikov, 

A. Strekachev, N. Dubrovskaya (Moscow, RUS)


12:00–13:00 

Bacteremia and endocarditis 

P460 Human leptospirosis in a regional Leptospira 

laboratory, Piemonte (Italy) 

L. Franzin, D. Cabodi, N. Bonfrate (Turin, I) 

P461 Streptococcus pneumoniae bloodstream 

infections: a clinical study of 460 episodes in 

the era of penicillin resistance 

V. Pintado, R. Blazquez, E. Loza, J. Fortun, 

J. Cobo, F. Dronda, P. Martin-Davila, S. Moreno 

(Madrid, E) 

P462 Streptococcus bovis bacteraemia: clinical 

characteristics of 41 episodes 

S. Higuet, B. Byl, O. Denis, M. Struelens, 

F. Jacobs (Brussels, B) 

P463 Infective endocarditis due to Leptospira 

grippotyphosa 

J. Benes, O. Dzupova, M. Kabelkova, 

R. Ondrejcak, R. Feuereisl, B. Horová 

(Prague, CZ) 

P464 Optimal dosage of azithromycin for the 

treatment of mild scrub typhus 

Y. Kim (Daejeon, KOR) 

P465 Clinical characteristics of infective endo - 

carditis: descriptive review of 262 epi sodes 

and risk factors for death 

S. Cicalini, C. Angeletti, E. Boumis, F. Palmieri, 

N. Petrosillo (Rome, I) 

P466 Risk and prognosis of community-acquired 

bacteraemia due to E. coli and other members 

of Enterobacteriaceae in patients with 

diabetes mellitus 

R.W. Thomsen, H.H. Hundborg, H.-H. Lervang, 

S.P. Johnsen, H.T. Sørensen, H.C. Schønheyder 

(Aalborg, Aarhus, DK) 

P467 Predictors of bacteraemia in hospitalised 

patients with infectious cellulitis 

J. Carratalà, N. Fernández-Sabé, B. Rosón, 

E. Marcos, L. Calatayud, V. Isern, J. Ribes, 

F. Gudiol (L´Hospitalet de Llobregat, Barcelona, E) 

P468 Cytokine profile and nitric oxide levels in sera 

of patients with acute brucellosis 

M. Refik, N.M. Bayraktar, Y. Ersoy, R. Durmaz 

(Malatya, TR) 

P469 The various clinical manifestations of 

brucellosis: a review of 43 cases 

A. Yuce, S. Alp Cavus, N. Yapar, N. Cakir 

(Izmir, TR) 

P470 Brucellar spondylitis (clinical manifestations 

and outcome of treatment in 32 cases) 

M.R. Hasanjani Roushan, S.M. Smailnejad Ganji, 

A. Ahmadi Ahangar (Babol, IR) 

P471 Successful treatment of Brucella melitensis 

endocarditis with antibiotic combination 

O. Ural, N. Dikici, D. Findik (Konya, TR) 

P472 Clinical features and prognosis of B. melitensis 

vertebral osteomyelitis. 

A descriptive study of 148 cases 

J.D. Colmenero, E. Jiménez-Mejías, M.A. Barón 

Ramos, J. Palomino-Nicás, J.D. Ruiz Mesa, 

J. Chacón, J.M. Reguera Iglesias, J. Pachón 

SAEI Study Group 

P473 Psychotic disorder related with Brucella 

infection: three case reports 

A. Celikbas, G. Bayam, S. Eren, O. Pazvantoglu, 

N. Baykam, B. Dokuzoguz (Ankara, TR) 

P474 Pulmonary involvement in brucellosis 

C.A. Hatipoglu, G. Bilgin, N. Tülek, U. Kosar 

(Ankara, TR) 

P475 Same involvement of brucellosis in two 

brothers: epididymoorchitis 

G. Tuncer Ertem, C. Ataman Hatipoglu, N. Tulek 

(Ankara, TR) 

P476 Human brucellosis: a retrospective evaluation 

of 75 cases 

N. Elaldi, I. Dokmetas, M. Bakir, M.Z. Bakici, 

M. Sencan (Sivas, TR) 

12:00–13:00 

Diagnostic methods – I 

P477 Comparision of proficiency testing among 

govermental and private sector hospital 

microbiology laboratories in Tehran 

M. Rahbar (Tehran, IR) 

P478 Implementation of particle analysers in the 

detection and description of biofilm formation 

R. Kadlec, J. Plocková, F. Ruzicka, V. Holá (Brno, CZ) 

P479 Laboratory variables in selected neuro - 

inflammatory diseases 

J. Bednarova, P. Stourac, H. Stroblova, 

A. Sevcikova (Brno, CZ) 

P480 Bactericidal effect of endox against various 

pathogens 

C. Cassanelli, S. Roveta, F. Cavallini, A. Marchese, 

E.A. Debbia, R. Armanino (Genoa, I) 


page 67


P481 Evaluation of Helicobacter pylori stool 

antigen test for the detection of Helicobacter 

pylori infection and comparison with other 

methods 

M. Ozdemir, R. Kesli, B. Baysal, M. Baykan, 

E. Kayacetin, M. Serdengecti (Konya, TR) 

P482 Comparison of the NOW ® ICT MALARIA P.f. 

/P.v. and the OptiMAL ® IT Rapid diagnostic 

tests for malaria in a non-endemic area 

F. Peyron, F. De Monbrison, P. Gérôme, 

J.F. Chaulet, M. Wallon, S. Picot (Lyon, F) 

P483 Identification of yeasts and yeast-like 

micro-organisms with a colorimetric card 

newly developed for the Vitek® 2 system 

D. Pincus, J. Mills, B. Knysak, A. Bassel, 

A. Fothergill, M. Rinaldi 

(Hazelwood, San Antonio, USA) 

P484 Compatibility of CPS ID 3, a new chromogenic 

medium, with the Vitek 2 system 

N. Fanjat, N. Garcia, S. Orenga, D. Robichon, 

C. Roger-Dalbert (La Balme les Grottes, F) 

P485 New improved VITEK 2 card for identification 

of Gram-negative bacilli 

B. Blanc, M. Babolat, L. Barbier, B. Celliere, 

L. Cordier, M.C Deluermoz, M. Guicherd, 

S. Petre, S. Chatellier, D. Monget 

(La Balme les Grottes, F) 

P486 Identification of Gram-positive bacteria with 

a new card developed for the VITEK 2 system 

M. Desmonceaux, S. Cagnès, N. Perrot, 

C.-F. Roger-Dalbert, L. Barbier, J.-S. Bonin, R. Fillet, 

X. Gansel, S. Chatellier, D. Monget 

(La Balme Les Grottes, F) 

P487 The IDEIA Norwalk-like virus (NLV) enzyme 

immunoassay (EIA) – a rapid method for 

screening outbreaks of non-bacterial 

gastroenteritis 

L. Butcher (Norwich, UK) 

P488 Blind protected telescopic catheter (PTC): 

a simple, reliable and cost-effective method 

for the diagnosis of the ventilator-associated 

pneumonia 

V. Koulourida, E. Martziou, K. Arvaniti, D. Lathyris, 

M. Drouggos, D. Matamis, M. Moskofidis 

(Thessalonica, GR) 

P489 Diagnostic and prognostic value of serum 

adenosine deaminase activity in scrub typhus 

H.Y. Kim, J.K. Kim, Y. Uh, W.Y. Lee, S.J. Yong, 

K.C. Shin (Wonju, KOR) 


P490 Early diagnosis of CJD: detection of 

14-3-3 proteins in the CSF of genetic form 

D. Slivarichova, E. Mitrova, V. Verchovodkova, 

V. Jovankovicova (Bratislava, SK) 

P491 A simple, isocratic reverse-phase ion-pair high 

performance liquid chromatography assay for 

cidofovir in human body fluids 

M. Darville, A. Lovering, A. MacGowan (Bristol, UK) 

12:00–13:00 

Antimicrobial susceptibility in Gram-negative 

bacteria – I 

P492 The activity of some quinolones against 

Stenotrophomonas maltophilia and 

Pseudomonas aeruginosa clinical isolates in 

the presence of pump inhibitors 

A.E. Laudy, I. Wojtal, A. Orzeszko, B.J. Starosciak 

(Warsaw, PL) 

P493 Effect of serum-susceptibility on the 

bactericidal activity of antimicrobials against 

Haemophilus influenzae 

I. Morrissey, D. Cooper, L. Williams, J. Shackcloth 

(London, UK) 

P494 Assessment of in vitro telithromycin activity 

against recent Haemophilus influenzae 

isolates recovered from adult patients in 

Spain 

M.I. Morosini, E. Loza, M. García Castillo, 

F. Almaraz, F. Baquero, R. Cantón (Madrid, E) 

P495 Bactericidal activity and synergy of rifampin 

alone and in combination against panresistant 

Acinetobacter baumannii 

M.E. Pachón-Ibañez, J. Paneque, F. Docobo-Perez, 

L. Arroyo, M. Ruiz, C. Llanos, A. Garcia-Curiel, 

M. Rodriguez (Seville, E) 

P496 Synergistic activities of nontraditional 

antibiotic combinations against multiresistant 

Pseudomonas aeruginosa and Acinetobacter 

baumannii strains 

F. Can, F. Ergin, M. Demirbilek, O. Kurt Azap, 

H. Arslan (Ankara, TR) 

P497 Cell surface hydrophobicity and adherence of 

Pseudomonas aeruginosa to abiotic surfaces: 

effect of subinhibitory concentrations of 

piperacillin/tazobactam 

A.P. Fonseca, P. Correia, C. Extremina, A. Bento, 

M. Martins, A. Fonseca, R. Tenreiro, J.C. Sousa 

(Porto, Lisbon, P)


P498 In vitro activity of antimicrobial drugs against 

Brucella melitensis strains in an endemic area 

N. Elaldi, M.Z. Bakici, M. Bakir, I. Dokmetas, 

M. Sencan (Sivas, TR) 

P499 Thermophilic Campylobacter resistance to 

five antimicrobial drugs 

B. Miljkovic-Selimovic, M. Mraovic, B. Potkonjak, 

T. Babic, B. Kocic, L. Ristic (Nis, Belgrade, CS) 

P500 In vitro activity of 12 antianaerobic agents 

against clinical Bacteroides fragilis group 

strains isolated over a 7-month period 

L. Alcalá, T. Peláez, N. García-Escribano, 

Ó. Pérez-Olaso, J. Martínez-Alarcón, J. Guinea, 

E. Bouza (Madrid, E) 

P501 The effect of sub-inhibitory concentration 

(sub-MIC) of amikacin and ciprofloxacin on 

the loss of capsular antigen K1 by Escherichia 

coli strains 

D. Wojnicz, A. Cisowska, S. Jankowski 

(Wroclaw, PL) 

P502 Antibiotic susceptibilities and extendedspectrum 

beta-lactamase production of 

Enterobacteriaceae from urinary tract 

infections 

B. Kocic, S. Antic, B. Tiodorovic, T. Babic, 

L. Ristic, V. Mladenovic (Nis, CS) 

P503 Agreement between disc diffusion and 

E-test methods to assess the carbapenem 

susceptibility of four Gram-negative 

nosocomial pathogens 

B. Cakir, S. Unal, O. Uzun (Ankara, TR) 

P504 Gram-negative nosocomial pathogens in 

Estonian intensive care units (ICUs) 

K. Lõivukene, E. Sepp, V. Adamson, Ü. Kallandi, 

K. Otter, P. Naaber (Tartu, Tallinn, EST) 

P505 Effects of subminimal inhibitory concentrations 

of three antimicrobials on the virulence 

factors and growth of Proteus mirabilis 

M. Ucar, S. Ozden, Y. Dogan, S. Kirdar, Ö. Yilmaz, 

H. Baskin (Izmir, TR) 

P506 In vitro susceptibility of Pseudomons aeruginosa 

isolated in a burn centre in south Iran, 

to silversulfadiazine and silver nitrate 

M. Hayati, A. Japoni, A. Alborzi, M. Kalani 

(Shiraz, IR) 

P507 Antimicrobial resistance among 

Streptococcus pneumoniae and Haemophilus 

influenzae from Africa and the Middle East: 

2002/2003 winter season 

A. Shibl, J. Daniels, J. Sievers and the 

SOAR in AME Study Group 

12:00–13:00 

Antifungal susceptibility studies 

P508 Comparative evaluation of AFST-EUCAST 

method and Sensititre YeastOne Colorimetric 

antifungal panel with NCCLS reference 

method for susceptibility testing of Candida 

species 

M. Yucesoy, C. Ergon (Izmir, TR) 

P509 Determination of antifungal activity of 

caspofungin using flow cytometry 

S. Costa-de-Oliveira, C. Pina-Vaz, C. Tavares, 

A. Gonçalves Rodrigues (Porto, P) 

P510 Paradoxical caspofungin effect: reduced 

activity against Candida albicans at high 

concentrations 

D.A. Stevens, T.C. White, D.S. Perlin, M. Espiritu, 

R. Parmar (San Jose, Seattle, Newark, USA) 

P511 Biofilms of Candida albicans on silicon 

catheters could be reduced by caspofungin 

in vitro 

C. Cocuaud, S. Imbert-Bouyer, M.-H. Rodier, 

C. Imbert (Poitiers, F) 

P512 In vitro activities of fluconazole and 

voriconazole against Spanish bloodstream 

isolates of Candida glabrata and Candida 

krusei 

G. Quindós, L. Sánchez, M. Villar, P. Ahuad, 

E. Eraso, J. Hernández (Bilbao, E; Mexico City, 

MEX; Buenos Aires, AR; Barakaldo, E) 

P513 Comparison of the in vitro activity of 

anidulafungin with amphotericin B, 

caspofungin, fluconazole, itraconazole and 

voriconazole against a panel of 780 yeast 

isolates obtained from five European centres 

E.M. Johnson, B.P. Goldstein, K.G. Davey, 

M.A. Fraser (Bristol, UK; Pen, USA) 

P514 The efficiency of fluconazole and amphotericin 

B in comparison with echinocandin 

micafungin and benzothiazole APB in Candida 

albicans and Candida dubliniensis isolated 

from HIV and cancer patients 

S. Melkusová, H. Bujdáková, A. Volleková, 

Y. Myoken, Y. Mikami 

(Bratislava, SK; Hiroshima, Chiba, JP) 

P515 Evaluation of a colorimetric antifungal 

susceptibility test by 2,3-diphenyl-5-thienyl- 

(2)-tetrazolium chloride 

C. Chang, J. Shin, J.-C. Choi, E.Y. Lee 

(Busan, KOR) 


page 69


P516 Antifungal activity of Juniperus turbinata on 

species of Candida and dermatophytes 

E. Pinto, C. Cavaleiro, L. Salgueiro, A. Palmeira, 

M. Gonçalves, C. Pina-Vaz, A. Gonçalves 

Rodrigues, S. Costa-de-Oliveira, C. Tavares, 

J. Martinez-de-Oliveira (Porto, Coimbra, P) 

P517 The effect of onion extract on ultrastructure 

of Trichophyton mentagrophytes and 

T. rubrum 

M. Shams, M. Godarzi, T. Tarihi, M. Razzaghi 

Abyaneh (Tehran, IR) 

P518 Effects of 5-hydroxytryptamine on virulence 

properties of Candida albicans in vitro 

A. Mayr, G. Hinterberger, M.-P. Dierich, 

C. Lass-Flörl (Innsbruck, A) 

P519 Studies on in vitro antimicrobial activity of 

vitreous substitutes against Candida albicans 

A. Szczepanik, E. Kosior-Jarecka, M. Wojtowicz, 

J. Mackiewicz, M. Koziol-Montewka (Lublin, PL) 

P520 Antifungal resistance patterns among oral 

Candida species from patients receiving 

anticancer therapy 

I. Glazar, M. Abram, S. Pezelj-Ribaric, B. Miletic, 

I. Brekalo Prso, B. Matica (Rijeka, Zagreb, HR) 

12:00–13:00 

Antibiotic resistance in respiratory pathogens 

P521 Changes in macrolide susceptibility of oral 

streptococci following administration of 

azithromycin or clarithromycin to healthy 

volunteers – A prospective randomised 

blinded trial 

J. Wagner, C. Klaus, H. Orawa, M. Pletz, 

M. Eisenblatter, W.E. Haefeli, H. Hahn, H. Lode 

(Berlin, Heidelberg, D) 

P522 Unchanged susceptibility of key respiratory 

pathogens to telithromycin post-introduction 

in Germany 

R. Reinert, A. Rodloff, D. Felmingham 

The PROTEKT Study Group 

P523 Prevalence of antimicrobial resistance and 

activity of the ketolide telithromycin against 

Haemophilus influenzae isolated from 

Japanese children 

K. Sunakawa, D. Farrell (Kanagawa, JP; London, UK) 

P524 Susceptibility of recent paediatric respiratory 

isolates of Streptococcus pneumoniae and 

Haemophilus influenzae in Spain 

C. Latorre, C. Garcia-Rey, J. Barron, A. Pinedo, 

J.M. Nogueira, J. Torres, L. Aguilar – The Spanish 

Surveillance Group for Respiratory Pathogens 


P525 Susceptibility of Haemophilus influenzae 

respiratory isolates from adults in Spain 

(2001–2002) 

A. Garcia-Perea, C. Garcia-Rey, C. Garcia-Riestra, 

R. Landinez, M. De-la-Rosa, P. Alomar, 

J. Garcia-de-Lomas, L. Aguilar – The Spanish 

Surveillance Group for Respiratory Pathogens 

P526 Antibiotic sensitivity of streptococci isolated 

in ear, nose and throat diseases – development 

of resistance from 1999 to 2002/2003 

K. Fickweiler, U. Fickweiler, A.C. Rodloff 

(Leipzig, D) 

P527 The comparative in vitro activity of 

moxifloxacin against respiratory tract 

pathogens isolated during 2003 from Libra 

Targeted Surveillance 

I. Morrissey, A. Colclough, L. Viljoen, K. Dowling, 

M. McKeon, T. Veltman (London, UK) 

12:00 – 13:00 

New drugs and novel therapeutic approaches 

P528 In vitro activity of synthetic peptides and 

mechanisms of resistance to colistin in 

pan-resistant Acinetobacter baumannii 

M. Rodriguez, J. Saugar, F. Docobo-Perez, 

J. Paneque, M.E. Pachón-Ibañez, J. Aznar, 

D. Andreu, L. Rivas, J. Pachón 

(Seville, Madrid, Barcelona, E) 

P529 New antimicrobial peptide active against 

methicillin-resistant Staphylococcus aureus, 

multiresistant coagulase negative staphylococci, 

and beta-haemolytic streptococci 

A. Jasir, F Kasprzykowski, V. Lindstrom, 

C. Schalen, A. Grubb (Lund, S; Gdansk, PL) 

P530 Comparison of azithromycin and amoxicillin 

for treatment of adult patients with solitary 

erythema migrans 

S. Lotric-Furlan, M. Logar, V. Maraspin, 

J. Cimperman, T. Jurca, F. Strle (Ljubljana, SI) 

P531 Comparative in vitro activity of ABT-492 and 

six other antimicrobial agents against 

anaerobic bacteria 

E. Sillerström, E. Wahlund, C.E. Nord (Stockholm, S) 

P532 Iclaprim, a novel diaminopyrimidine 

antibiotic: synergy studies with different 

classes of antibiotics 

L. Weiss, D. Gillessen, S. Hawser, K. Islam 

(Munchenstein, CH)


P533 Anti-pneumocystis activity of iclaprim, a 

reliable therapeutic alternative against 

Pneumocystis pneumonia 

E.M. Aliouat, E. Dei-Cas, N. Gantois, K. Islam, 

S. Hawser (Lille, F; Munchenstein, CH) 

P534 In vitro plasma fibrin clot models versus in 

vivo models of experimental endocarditis: 

case study for diaminopyrimidine antibiotics 

iclaprim and trimethoprim/sulfamethoxazole 

J.M. Entenza, M. Giddey, J. Vouillamoz, 

S. Hawser, P. Moreillon (Lausanne, Basle, CH) 

P535 Antimicrobial activity of the novel 

cephalosporin LB11058 tested against 

pathogens commonly associated with 

bacterial meningitis 

H. Sader, D. Johnson, D.J. Biedenbach, R. Jones 

(North Liberty, USA) 

P536 Gram-negative bacteria producing 

characterised beta-lactamases: in vitro 

activities of BAL9141 and comparators 

M. Kresken, M. Heep, I. Wiegand 

(Bonn, D; Basel, CH) 

P537 MIC determination of the anti-pneumococcal 

activity of BAL 9141 compared to other agents 

P. Appelbaum, D. Hoellman, M. Jacobs 

(Hershey, Cleveland, USA) 

P538 Efficacy and safety of pharmacokinetically 

enhanced amoxicillin/clavulanate 2000/125 mg 

in adult patients with acute bacterial sinusitis 

in Hungary 

L. Tamas, P. Kovacs, G. Horvai, M. Twynholm 

(Budapest, HUN; Harlow, UK) 

P539 An in vitro evaluation of the antimicrobial 

activity of a novel fluoroquinolone 

M.J. Robbins, D. De Rubeis, C. Dencer, 

L. Williams, M. Harrison, A. Bryskier, 

D. Felmingham (London, UK; Romainville, F) 

P540 Intracellular penetration and activity of 

cethromycin against Legionella pneumophila 

in a monocytic cell line (Mono Mac 6) 

I. García, S. Ballesta, E.J. Perea, Á. Pascual 

(Seville, E) 

P541 Phase 2 trial comparing four regimens of 

oritavancin vs comparator in the treatment 

of patients with S. aureus bacteraemia 

J.S. Loutit, W. O'Riordan, J. San Juan, J. Mensa, 

R. Hanning, S. Huang, S. Porter 

(Brisbane, Chula Vista, USA; Buenos Aires, AR; 

Barcelona, E) 

P542 Linezolid in the treatment of skin and soft 

tissue infections caused by methicillinresistant 

Staphylococcus aureus 

N. Alikadic, D. Smrke (Ljubljana, SI) 

P543 Linezolid tolerance among multiresistant 

nasopharyngeal isolates of Streptococcus 

pneumoniae 

A. Malm, I. Korona-Glowniak, A. Kalasiewicz 

(Lublin, PL) 

P544 New penams (6-APA) and cephems (7-ACA) 

with bulky T-shaped side-chains: synthesis 

and antibiotic activities 

L. Efron, T. Happaerts, E. Sonveaux, H. Chanteux, 

Y. Glupczynski, C. Behrin, F. Van Bambeke, 

P. Tulkens (Brussels, B) 

P545 In vitro and in vivo activities of novel 

compounds active against multiresistant 

strains of Mycobacterium tuberculosis 

U. Möllmann, L.P. Martinova, S. Rüsch-Gerdes, 

V.A. Makarov (Jena, D; Moscow, RUS; Borstel, D) 

P546 Basidiomycete metabolites attenuate 

virulence properties of Candida albicans in 

vitro 

L. Pleyer, S. Ressler, A. Berg, M.P. Dierich, 

R. Würzner (Innsbruck, A; Jena, D) 

P547 Search and assessment of novel substances 

active against Epstein-Barr virus 

S. Zagorodnya, N. Dyachenko, N. Nesterova, 

V. Atamaniuk, A. Novik, S. Rybalko, G. Baranova 

(Kiev, UKR) 

P548 A phase 2 study of the toxin binding polymer 

tolevamer in patients with C. difficile 

associated diarrhoea 

D. Davidson, J. Peppe, T. Louie – 

The Tolevamer Working Group 

P549 A novel antimicrobial system to treat 

methicillin-resistant and glycopeptideresistant 

staphylococci 

B. Cookson, M. Embleton, S. Nair, M. Wilson 

(London, UK) 

P550 Novel “ethiological” therapies for AIDSrelated 

Kaposi's sarcoma, and possible 

laboratory monitoring 


P551 A novel antiviral based on oral antibodies: 

clinical benefits in paediatric upper 

respiratory infections 

A.V. Martyushev-Poklad, V.F. Uchaikin, 

M.P. Kotelnikova, J.L. Dugina, O.I. Epstein, 

S.A. Sergeeva (Moscow, RUS) 


page 71


P552 Disruption of the interaction between the 

HCMV DNA polymerase subunits: toward 

new anti-HCMV inhibitors 

A. Loregian, B. Appleton, J.M. Hogle, 

H.S. Marsden, D.M. Coen, G. Palù 

(Padova, I; Boston, USA; Glasgow, UK) 

12:00–13:00 

MRSA and staphylococci: epidemiology 

P553 MRSA outbreaks in nursing homes in central 

Norway 

K.W. Larssen, G. Iversen, T. Jacobsen, K. Bergh, 

O. Scheel (Trondheim, N) 

P554 Prevalence and risk factors for colonisation 

with methicillin-resistant Staphylococcus 

aureus in residents of long-term-care facilities 

in Greece 

V. Grammelis, K. Kanellakopoulou, A. Kapaskelis, 

M. Gika, K. Volonaki, A. Merkouris, G. Greka, 

H. Giamarellou, M.K. Lazanas (Athens, GR) 

P555 Risk factors for nasal carriage of methicillinresistant 

Staphylococcus aureus among 

patients in long-term care facilities in Korea 

S.-H. Eun, Y.-S. Lee, J.-K. Lee, J.-I. Yoo, J.-O. Cha, 

B.-S. Kim (Seoul, KOR) 

P556 The prevalence of nasal colonisation with 

MRSA among residents of long-term care 

facilities in South Korea 

Y.S. Lee, J.-O. Cha, J.-O. Ahn, J.-K. Lee, J.-I. Yoo, 

S.-H. Eun, B.-S. Kim (Seoul, KOR) 

P557 Basic hospital infection control methods 

reduced the isolation rate of methicillinresistant 


E.S. Kim, E. Heo, D.H. Whang, H. Yum, B. Shin, 

H. Ko, B.H. Jun (Seoul, KOR) 

P558 Molecular surveillance of clinical methicillinresistant 

Staphylococcus aureus isolates in 

neonatal intensive care units 

Y.-C. Huang, L.-H. Su (Kweishan, TW) 

P559 Methicillin-resistant Staphylococcus aureus 

bacteraemia in neonatal intensive care units: 

genotyping analysis and case-control study 

P.-W. Chung, Y.-C. Huang, C.-Y. Lee, L.-H. Su, 

T.-Y. Lin (Kweishan, TW) 

P560 Delineation of the endemic and sporadic 

clones among methicillin-resistant 

Staphylococcus aureus strains in a Czech 

hospital 

O. Melter, M. Aires de Sousa, K. Laskafeldová, 

P. Urbásˇková, M. Wünschová, H. de Lencastre 

(Prague, CZ; Oeiras, P; Novy´ Jièín, CZ; 

New York, USA) 


P561 MRSA – Emerging issue in a university 

hospital, Hradec Kralove 

V. Dostal, K. Honegr, S. Plisek, J. Beran, 

M. Moravkova, E. Mickova, J. Manak, J. Kajzr, 

P. Dostal, L. Prokes, P. Bradna, A. Lukes, 

J. Tosner, P. Moravek, J. Harrer, J. Sykorova 

(Hradec Kralove, CZ) 

P562 Epidemiological analysis of the incidence of 

MRSA infections in hospitals in the Czech 

Republic 

B. Macková, O. Melter, P. Urbásˇková (Prague, CZ) 

P563 Evolution of two different clones of 


isolated in Italy 

F. Campanile, D. Bongiorno, S. Borbone, 

V. Cafiso, F. Di Bassiano, S. Stefani (Catania, I) 

P564 Methicillin resistance in staphylococci: 

results of a survey in a northern Italian region 

R. Bandettini, M. Lemmi, L. Pescetto, 

A. Scaramuccia, E.A. Debbia 

for Ligurian AMCLI group, Italy 

P565 Methicillin-resistant staphylococci in a 

surgical hospital: incidence, antimicrobial 

susceptibility, molecular typing 

A. Zilevica, T. Tracevska, R. Treimane, R. Paberza, 

I. Vingre (Riga, LV) 

P566 Initial molecular characterisation of the first 

MRSA outbreak at a clinical university 

hospital 

E. Miklasevics, A. Balode, U. Dumpis, 

A. Martinsons (Riga, LV) 

P567 Clonal spread of borderline oxacillin-resistant 

Staphylococcus aureus in a dermatological 

hospital unit 

M.K. Thomsen, M. Rasmussen, K. Fuursted, 

L.N. Pedersen, M. Deleuran, J.K. Møller 

(Aarhus, DK) 

P568 The use of molecular epidemiology to 

monitor the nosocomial fissemination of 


in a tertiary care university hospital during 

a 10-year survey: 1991–2001 

A.L. Beretta, P. Trabasso, R.B. Stucchi, 

M.L. Moretti (Sao Paulo, BR) 

P569 Epidemiology of methicillin-resistant 

Staphylococcus aureus at a German 

university hospital 

H. Haefner, C. Bauer, S. Koch, F. Huenger, 

S.W. Lemmen (Aachen, D)


P570 Nosocomial meningitis due to methicillinresistant 

Staphylococcus aureus: 

review of 8 cases 

B. Arda, T. Yamazhan, O. Sipahi, S. Islekel, 

C. Buke, S. Ulusoy (Izmir, TR) 

P571 Effect of an intervention programme on the 

MRSA outbreak in an Aberdeen infirmary 

J.-M. Lopez-Lozano, A. Beyaert, F.M. MacKenzie, 

R. Wilson, D. Stuart, I.M. Gould 

(Orihuela, Murcia, E; Aberdeen, UK) 

P572 How dangerous is the environment of a 

patient with respect to transfer of MRSA 

S. Maxwell, M. Wiggins (Stockport, UK) 

P573 Antibiotic usage and environmental 

reservoirs maintain methicillin-resistant 

Staphylococcus aureus on an intensive care 

unit 

K.J. Hardy, P.M. Hawkey, B.A. Oppenheim, 

F. Gao (Birmingham, UK) 

P574 Monitoring outbreaks of MRSA in a university 

hospital, Innsbruck by automated ribotyping 

K. Grif, D. Orth, R. Würzner, M. Dierich, 

F. Allerberger, C. Lass-Flörl (Innsbruck, A) 

P575 MRSA acquisition on an intensive care unit 

S. Dancer, M. Coyne, A. Speekenbrink, 

S. Samavedam, J. Kennedy, P. Wallace 

(Glasgow, UK) 

P576 Control of methicillin-resistant Staphylococcus 

aureus transmission in an intensive care unit: 

evaluation of the efficacy of control practices 

G. Guerrier, L. Bodin, S. Males, J.M. Ekherian, 

D. Resiere, J.J. Rouby (Paris, F) 

P577 Emergence of a VISA strain in a patient with 

osteomyelitis: first isolation reported from 

Austria 

A. Wechsler-Fördös, N. Isufovski, F. Geppert, 

T.R. Walsh (Vienna, A; Bristol, UK) 

P578 Six lethal cases of community-acquired 


infections in young adults in Montevideo, 

Uruguay 

A. Galiana, W. Pedreira, K. Hiramatsu, X.X. Ma, 

T. Ito, O. Bertaux, I. Constenla, I. Christophersen, 

H. Bagnulo (Montevideo, UY; Tokyo, JP) 

P579 S. aureus community-acquired infections. 

Antibiotic resistance rates and macrolide 

resistance phenotypes 

Sp. Fokas, St. Fokas, F. Markatou, E. Lauranou, 

M. Kalkani, M. Dionysopoulou (Sparta, GR) 

P580 An epidemic European fusidic acid resistant 

strain of Staphylococcus aureus carries the 

fusB determinant 

A.J. O'Neill, A.R. Larsen, A.S. Henriksen, 

I. Chopra (Leeds, UK; Copenhagen, DK) 

12:00–13:00 

MRSA and staphylococci: laboratory aspects 

P581 Susceptibility of pulse field characterised 


to daptomycin 

R. Smyth, G. Kahlmeter (Växjö, S) 

P582 usefulness of mec-associated dru sequences 

in monitoring the spread of highly clonal 

epidemic methicillin-resistant Staphylococcus 

aureus isolates in Scotland 

R.V. Goering, D. Morrison, K.F.C. Cooper, 

Z. Al-Doori, G.F.S. Edwards, C.G. Gemmell 

(Omaha, USA; Glasgow, UK) 

P584 Use of polyvalent anti-staphylococcal 

bacteriophages for the biocontrol of 


and other staphylococci 

A. Coffey, S. O’Flaherty, W. Meaney, M. Elbreki, 

R. Ross (Cork, IRL) 

P585 Evaluation of cefoxitin MIC determination to 

detect low-level methicillin-resistant 

Staphylococcus aureus by the automatic 

system Phoenix 

A. Felten (Paris, F) 

P586 The stability of mecA genes and MIC values of 

methicillin in passage-selected vancomycinresistant 

EMRSA strains isolated in the UK 

I. Alshami, S.A.H. Awad, J.P. Burnie 


P587 Susceptibity of methicillin-resistant strains 

of S. aureus isolates from nasal carrier 

to mupirocin and bacitracin in a Tehran 

hospital, Iran 

M. Rahbar, K. Bahar, M. Yaghobi, A. Reza Shajari 

(Tehran, IR) 

P588 Aminoglycoside-resistance genes and 

phenotypes in multiresistant nosocomial 

strains of Staphylococcus aureus 

M. Malossi, S. Cresti, S. Pollini, C. Cellesi, 

G. Amicosante, G.M. Rossolini (Siena, L'Aquila, I) 


page 73


P589 Frequency of glycopeptide intermediate and 

hetero-glycopeptide intermediate 

Staphylococcus aureus among methicillinresistant 

strains isolated in 2002 in a Warsaw 


G. Mlynarczyk, A. Mlynarczyk, M. Luczak 

(Warsaw, PL) 

P590 Methicillin-resistance expression mediated 

by subinhibitory concentrations of 

fluoroquinolones in MRSA 

J.L. Muñoz Bellido, S. Hernández Iglesias, 

R. Marín Jiménez, J.A. García-Rodríguez 

(Salamanca, E) 

P591 Screening criteria for glycopeptide 

susceptibility of methicillin-resistant 

Staphylococcus aureus revisited for two 

periods of blood cultures isolates 

L. Bernard, P. Vaudaux, P. Rohner, E. Huggler, 

M. Armanet, D. Pittet, D.P. Lew, J. Schrenzel 

(Geneva, CH) 

P592 Sequence analysis of the polymorphic region 

X of protein A in a methicillin-sensitive 

Staphylococcus aureus population isolated 

from the airways of cystic fibrosis patients 

B. Kahl, A. Mellmann, S. Deiwick, G. Peters, 

D. Harmsen (Munster, D) 

P593 Ridom StaphType software: facing the 

challenge of inter-laboratory evaluation of 

sequence-based MRSA typing 

A. Mellmann, D. Harmsen, A.W. Friedrich, 

J. Rothgänger, H. Claus, U. Vogel, H. Karch 

(Munster, Wurzburg, D) 

P594 Intracellular killing of drug-resistant 

Staphylococcus aureus by different 

antibiotics 

F. Rozgonyi, C. Gemmell (Budapest, HUN; 

Glasgow, UK) 

P595 MRSA with Panton-Valentine leukocidin in 

Germany 

W. Witte, C. Braulke, C. Cuny, B. Strommenger, 

G. Werner (Wernigerode, D) 

P596 Characterisation of methicillin-resistant 

Staphylococcus aureus isolated at a policlinic 

in Bari, Italy 

M. Corrente, R. Monno, M. Totaro, G. Normanno, 

I. De Giglio, A. Lorusso, C. Buonavoglia 

(Valenzano, Bari, I) 


12:00–13:00 

Parasitic diseases 

P597 Detection of Giardia lamblia in stool samples 

by enzyme immunoassays 

N. Miladinovic-Tasic, S. Tasic, A. Tasic, 

D. Zdravkovic, I. Tasic (Nis, CS) 

P598 Epidemiological features of intestinal 

parasitosis in a children's hospital in Athens 

I. Varzakakos, H. Damaskopoulou, A. Makri, 

L. Papavasileiou, H. Papavasileiou (Athens, GR) 

P599 Survey of intestinal parasitic infections 

among physical and mental retardees in 

a maintenance centre, Taft 

M.H. Anvari Tafti, A.A. Jafarri Nodoushan, 

A. Fattahi Bafghi (Yazd, IR) 

P600 Intestinal parasites in a paediatric hospital 

population in Madrid (Spain), January 2002 to 

October 2003 

A. Morente, V.M. Martínez, R. De Julián, 

M. Baquero, M. Subirats (Madrid, E) 

P601 A 3-year descriptive study of intestinal 

parasite infections in outpatients in Madrid, 

Spain (2000–2002) 

P. Tajada Alegre, M. García-Collía, L. Zapatero, 

F. Bolás, M. Subirats, M. Baquero, J.L. Gómez- 

Garcés (Madrid, E) 

P602 Enteropathogenic bacteria isolated from 

patients with diarrhoea: frequency of 

isolation and susceptibility testing to commonly 

used antibiotics in a Tehran hospital: 

a one-year study 

B. Kiadarbandisari (Tehran, IR) 

P603 Intestinal parasites found in native and 

foreign workers during a seven-year period 

in Greece 

J. Spiliopoulou, M. Palta, V. Nickolas, 

V. Petrocheilou-Paschou (Athens, GR) 

P604 Prevalence of intestinal parasites in women 

15-45 years old (in pregnancy age) in a 

healthy village (Kargan), in Ardabil, Iran 

A. Daryani, M. Dehghan (Ardabil, IR) 

P605 Cryptosporidiosis associated with child care 

settings in Madrid, Spain 

P. Tajada Alegre, M. García-Collía, L. Zapatero, 

F. Bolás, M. Subirats, M. Baquero, J.L. Gómez- 

Garcés (Madrid, E) 

P606 Cryptosporidiosis in children 

A.M. Garcia-Tapia, P. Marin-Casanova, C. Lopez, 

J. Ruiz-Aragon, C. Fernadez, M. Martin, 

P. Garcia-Martos (Cadiz, E)


P607 Human and animal trichinellosis in Belgrade 

Z. Dakic, Z. Kulisic, B. Antonijevic, R. Dmitrovic, 

M. Jovanovic, M. Petrovic (Belgrade, CS) 

P608 Study of rodents and their parasitic infections 

in Bandar Abbas City, southern Iran 

M. Shahi, A.A. Hanafi-Bojd, M. Soleimani-Ahmadi, 

G. Zamani, G. Mohseni (Bandar Abbas, IR) 

P609 Epidemiology of Blastocystis hominis and 

other intestinal parasites in female marriage 

emigrants in Taiwan 

J.W. Shin, H.S. Cheng (Tainan, TW) 

P610 Characterisation of casein kinase 1 in 

Trichomonas vaginalis 

P. Tang, C.H. Huang (Taoyuan, TW) 

P611 Comparison of direct microscopy and in vitro 

cultures in detection of Trichomonas vaginalis 

G. Sönmez Tamer, D. Öztürk Dündar, S. Caliskan, 

E. Doger (Kocaeli, TR) 

P612 Seroprevalance of Toxoplasma gondii 

infection among some risk groups in 

Erzurum, Turkey 

A.E. Aktas, H. Yazgi, M. Ertek, A. Ayyildiz 

(Erzurum, TR) 

P613 Comparison of DNA extraction methods and 

PCR assays for detection of Toxoplasma 

gondii 

B. Edvinsson, S. Jalal, B. Evengård 

ESGT 

P614 Evaluation of the ELISA IgE test for diagnosis 

of acute toxoplasmosis 

P. Kodym, V. Tolarova, A. Lehovcova, M. Maly 

(Prague, CZ) 

P615 Effect of testing for IgG avidity for sero - 

diagnosis of toxoplasmosis in pregnant 

women 

D. Findik, U. Arslan, O. Ural, I. Tuncer (Konya, TR) 

P616 Can free-living amoebae be an environmental 

niche for Vibrio cholerae? 

H. Abd, A. Weintraub, G. Sandström (Stockholm, S) 

12:00–13:00 

Tropical and parasitic diseases 

P617 Characteristics of 117 malaria cases in Turkey 

A. Celikbas, O. Ergonul, S. Eren, N. Baykam, 

T. Guven, B. Dokuzoguz (Ankara, TR) 

P618 Relapse rate of vivax malaria with shorter 

duration of antirelapse treatment in Iran 

M. Salehi-Shaban, M. Esmailzadeh (Zahedan, IR) 

P619 Persistent HRP2 and pan-malarial antigen 

reactivity after successful treatment of 

P. falciparum infection 

J. Iqbal, N. Khlaid, P. Hira (Kuwait, KWT) 

P620 Drug resistance to malaria in Orissa 

P. Bishnu Prasad (Bhubaneswar, IND) 

P621 In vitro recrudescence of P. falciparum 

parasites suppressed to dormant state by 

atovaquone alone and in combination with 

proguanil 

M. Thapar, P. Gil, A. Björkman (Stockholm, S) 

P622 Typhoid and paratyphoid fever in the Czech 

Republic, 1993–2003 

H. Ambrozova, J. Vanista, M. Reisingerova, 

C. Benes (Prague, CZ) 

P623 Imported Dengue fever in the Czech Republic 

P. Chalupa, N. Sojkova, J. Januska 

(Brno, Prague, Ostrava, CZ) 

P624 Contribution of PCR in laboratory diagnosis of 

visceral leishmaniasis 

S. Mitka, L. Ftika, H. Chaidouli, P. Mamasi, 

D. Arvanitis, C. Psillaki, A. Kansouzidou 

(Thessaloniki, GR) 

P625 Haemophagocytic syndrome associated with 

visceral leishmaniasis 

B. Kilani, L. Ammari, S. Abdellatif, E. Chaker, 

F. Kanoun, T. Ben Chaabane (Tunis, TN) 

P626 Detection of Leishmania major in visceral 

infection by a nested-PCR assay 

M. Karamian, M. Motazedian, K. Gholami 

(Shiraz, IR) 

P627 Study of glucantime resistance in cutaneous 

leishmaniasis by PCR-RFLP method in Shiraz, 

Iran 

M. Motazedian, M. Karamian, S. Ardehali 

(Shiraz, IR) 

P628 Subconjunctival Dirofilaria repens infection 

confirmed by PCR-based approach 

A. Dzamic, I. Radonjic, V. Arsic Arsenijevic, 

S. Mitrovic, I. Kranjcic Zec (Belgrade, CS) 

P629 First cases of Acanthamoeba keratitis in 

Slovakia 

F. Ondriska, M. Mrva, M. Lichvar, P. Ziak, 

Z. Murgasova, E. Nohynkova 

(Bratislava, Martin, Nitra, SK; Prague, CZ) 

P630 First report of human myiasis caused by 

Chrysomya bezziana Villeneuve (Diptera; 

Calliphoridae) in Iran, May 2002 

K. Akbarzadeh, A. Jahanian, M. Nateghpour, 

S. Tirgari (Tehran, Iranshahr, IR) 


page 75


P631 Imported case of brucellosis complicated by 

liver abscess 

C. Mutini, M. Di Carlo, L. Coppolaro, 

A. Di Girolamo, E. Pizzigallo (Chieti, I) 

P632 Neurobrucellosis: report of five cases 

A. Yuce, B. Karaca, S. Alp Cavus, E. Idiman, 

F. Idiman, N. Yapar (Izmir, TR) 

P633 Evaluation of available stains for detection of 

Acanthamoeba sp. from brain specimen. 

An assessment 

G. Gonzalez Mediero, P. Santiago, M. Seijo, 

G. Visvesvara (Vigo, Pontevedra, E; Atlanta, USA) 

P634 Leptomeningeal form of neurocysticercosis 

with chronic meningitis 

S. Nikolic, G. Stevanovic (Belgrade, CS) 

P635 Distribution of soft and hard ticks and their 

association with Borrelia and C.C.H.F in 

Isfahan province, Iran 

M. Motavalli Emami, B. Ataei, M. Khademi, 

A. Omoumi, M. Hamdi (Isfahan, IR) 

P636 The occurrence of Entamoeba gingivalis in 

patients with periodontal diseases 

D. Wojnicz, J. Sarowska, Z. Kozlowski 

(Wroclaw, PL) 

12:00–13:00 

Meningitis 

P637 Demographic, clinical and laboratory data in 

140 meningococcal disease cases 

A.R. Emami Naeini (Isfahan, IR) 

P638 Laboratory surveillance of meningococcal 

disease in Portugal 

M.J. Simões, L. Brum, C. Furtado on behalf of 

the Laboratory Meningococcal Disease Network 

P639 Multidisciplinary research of meningococcal 

invasive disease in the Czech Republic 

E. Kasal, V. Struncova, P. Krizova, I. Chytra, 

I. Martinkova, I. Subrt, O. Dzupova, V. Dostal, 

L. Roznovsky, T. Habanec, P. Chalupa, 

D. Barnetova, L. Nalos, (Pilsen, Prague, Hradec 

Kralove, Ostrava, Brno, CZ) 

P640 Community-acquired enterococcal meningitis 

caused by Enterococcus casseliflavus. 

First case report 

C. Iaria, G. Stassi, R. Di Leo, A. Toscano, 

A. Cascio (Messina, I) 

P641 Factors predicting fatal outcome of purulent 

meningitis 

O. Dzupova, J. Benes, M. Helcl, J. Prihodova 

(Prague, CZ) 


P642 Dexamethasone therapy for bacterial 

meningitis in south-eastern Anatolia region of 

Turkey 

C. Ayaz, M.K. Celen, S. Hosoglu, M.F. Geyik, 

M. Ulug (Diyarbakir, TR) 

P643 Serologic evidence of Borrelia burgdorferi 

infection among patients hospitalised with 

tick-borne encephalitis 

S. Grygorczuk, M. Kondrusik, S. Pancewicz, 

J. Zajkowska, T. Hermanowska-Szpakowicz 

(Bialystok, PL) 

P644 Spinal epidural abscess in the MRI age 

F.J. Fernández-Fernández, S. Pérez-Fernández, 

J. de la Fuente-Aguado, B. Sopeña-Pérez Argüelles, 

C. Martínez-Vázquez (Vigo, E) 

12:00–13:00 

HIV 

P645 Genotype-guided treatment change in 

previously heavily antiretroviral treatment 

HIV patients 

E. Arroyo, C. Tampe, G. Gonzalez, S. Saavedra, 

C. Rivera-Vazquez, C. Ramirez-Ronda 

(San Juan, PR) 

P646 Lipodystrophy as paradoxically marker of 

efficacy of antiretroviral therapy in AIDS 

patients: our experience 

M. Terra, S. Pellicanò, R. Calzone, 

A.C. Del Giudice, D. Teti, F. Rombolà, 

S.N. Bertuccio, L. Terra (Crotone, I) 

P647 Head-to-head comparison between firstchoice 

HAART in antiretroviral-naive patients 

with HIV infection: lopinavir/ritonavir- versus 

efavirenz-based therapy 


P648 Polyunsaturated fatty acid ethyl ester as 

therapy of hypertriglyceridaemia related to 

HIV infection treated with antiretrovirals 


P649 Pharmacokinetics of non-nucleoside 

inhibitors of HIV-1 reverse transcriptase of 

the DATA/DAPY classes of compounds 

P.J. Lewi, K. Andries, A.I. Archakov, E. Arnold, 

H.H. Bohets, A.D. Clark, F.F.D. Daeyaert, K. Das, 

M.-P. de Béthune, M.R. de Jonge, Y. Frenkel, 

J. Heeres, Y.D. Ivanov, L.M.H. Koymans, 

A.V. Lisitsa, J. Peeters, P. Timmerman, 

G. van't Klooster, H.M. Vinkers, P.A.J. Janssen 

(Vosselaar, Mechelen, B; Moscow, RUS; 

Piscataway, USA; Beerse, B)


P650 Restoration of complement-mediated 

phagocytosis in HIV-1 infected macrophages 

by 2’5’dideoxyadenosin (ddAD) 

D. Doischer, A. Jaworowski, U. Frank, S. Crowe 

(Freiburg, D; Melbourne, AUS) 

P651 CD4+ T-lymphocytes counts at AIDS among 

patients treated by highly active antiretroviral 

therapy or other antiretroviral regimens 

A. Gayet-Ageron, N. Voirin, D. Peyramond, 

C. Chidiac, C. Trepo, J.-L. Touraine, B. Issartel, 

B. Ponceau, P. Miailhes, J.-L. Livrozet, J. Fabry, 

P. Vanhems (Lyon, F) 

P652 Gender differences in HIV RNA and CD4 

counts, but not in AIDS-defining illnesses and 

CD4-based HAART initiation threshold, in new 

entrants to HIV care in Cleveland, Ohio 

C.V. Loupa, B. Rodriguez, H. Valdez, R.A. Salata, 

M.V. Lisgaris, B. Gripshover, G. McComsey, 

S. Fulton, M.M. Lederman 

(Cleveland, Ridgebury, USA) 

P653 Incidence and predictors of opportunistic 

infections and mortality in HIV/AIDS patients 

admitted to a university hospital: 

a 16-year follow-up 

G. Sain Güven, N. Aydemir, B. Cakir, O. Uzun, 

S. Ünal (Ankara, TR) 

P654 Venezuelan HIV patients and prevalence of 

HPV infection in anal samples 

M. Correnti, M.E. Cavazza Porro, R. Alfonso, 

E. Arias, M.E. Avila, M. Uribe (Caracas, VE) 

P655 HCV viraemia and the degree of hepatic 

affectation in HCV-HIV co-infected patients 

S. Garcinuño, I. Guilabert, T. Alvarez Gago, 

M.A. del Pozo, J. Arias, B. Sánchez Borge, 

M.A. Mantecón, M.A. Bratos, A. Orduña, 

A. Rodríguez Torres (Valladolid, E) 

P656 Prevalence of GBV-c/HGV in HIV-infected 

patients and potential influence of coinfection 

on the course of the disease 

V. Aster, J. König, M. Stanková, H. Rozsypal, 

B. Prochazka (Prague, CZ) 

P657 Cardiovascular neurovegetative dysfunction 

in HIV-infected patients 

S. Cicalini, G. Raimondi, P. Noto, E. Boumis, 

S. Sacco, C. Saltini, N. Petrosillo (Rome, I) 

P658 Pancreatic abnormalities during HIV infection. 

What about epidemiology, management, and 

outcome? 


P659 Laboratory and clinical pancreatic abnorm - 

alities during HIV infection treated with 

antiretroviral therapy 


P660 Antiretroviral treatment and gynecomastia: 

which correlations? 


P661 Lipomatosis and HIV disease during 



P662 Drug-induced alopecia after lopinavir/ 

ritonavir (Kaletra) treatment 

G. Chrysos, A. Pastelli, S. Mikros, F. Stasini, 

E. Friligou, L. Karampali, P. Spyropoulou 

(Athens, GR) 

P663 Modification of lipid parameters during 

structured interruptions of treatment in HIV 

chronically infected patiens 

M. Montes de Oca Arjona, R. García Juárez, 

A. Martin-Aspas, R. Perez-Cano, F. Brun Romero, 

C. Fernandez Gutierrez, J. Girón-González 

(Cádiz, E) 

P664 Metabolic changes in HIV-infected patients on 

HAART 

E. Valadas, H. Chaves Ramos, J. Cruz, C. Ribeiro, 

L. Caldeira, F. Antunes (Lisbon, P) 

P665 Nephrolitiasis induced by indinavir plus 

boosting dose of ritonavir in a Belgrade study 

population 

G. Dragovic, D. Jevtovic (Belgrade, CS) 

P666 Prevalence of resistance mutations in subtype 

F strains isolated from Romanian naïve 

children 

D. Otelea, S. Manaila, M. Dinu, D. Banica, 

M. Tinischi, D. Maxim (Bucharest, RO) 

P667 Phylogenetic analysis of subtype F HIV 1 

strains isolated in Romania 

D. Otelea, G. Oprisan, M. Dinu, S. Manaila, D. 

Banica, M. Tinischi, D. Maxim (Bucharest, RO) 

P668 Comparison of line probe assay versus 

sequence analysis for detection of human 

immunodeficiency virus type 1 (HIV-1) 

mutations conferring resistance to 

antiretroviral drugs 

S. García-Bujalance, C. Ladrón de Guevara, 

A. Sánchez-Maroto, A. Gutiérrez (Madrid, E) 

P669 Evaluation of the Roche COBAS TaqMan 

48 HIV-1 test 

J. Djupsjöbacka, K. Sopenlehto, H. Piiparinen, 

M. Lappalainen, J. Suni (Helsinki, FIN) 


page 77


P670 Comparison of two commercial assays for the 

quantification of HIV-RNA 

L. Valdés, S. García-Bujalance, M.P. Romero, 

C. Ladrón de Guevara (Madrid, E) 

P671 Evaluation of a simplified protocol of the 

Versant bDNA HIV 3.0 for HIV-1 viral load 

quantitation 

F. Salvá, M. Rotger, E. Ruiz, H. Machado, 

M. Gaya, C. Alonso, J.L. Perez 

(Palma de Mallorca, E) 

P672 HIV-1 viral load by NucliSens EasyQ HIV-1 

v1.1 in combination with the NucliSens mini 

MAG instrument 

P. van Deursen, T. Oosterlaken, T. Cuypers, 

A. Verhoeven, P. de Bie, R. Bosch, I. Berghuis, 

M. Jacobs, P. van de Wiel (Boxtel, Amsterdam, NL) 

P673 Comparative study of two techniques to 

measure HIV-1 viral load in a French 

commercial laboratory 

G. Kreplak, R. Legouge (Paris, F) 

P674 Evolution of hypervariable region 1 of 

hepatitis C virus in HIV- HCV co-infected 

patients after treatment with highly active 


M. Solmone, E. Lalle, E. Girardi, G. Antonucci, 

P. Pizzaferri, G. Migliorino, M. De Marco, 

M.R. Capobianchi, A. D'Arminio Monforte – 

I.Co.N.A. Study Group 

13:00–14:00 

Antimicrobial resistance mechanisms – I 

P675 Development of endogenous resistance by 

staphylococci to BAL9141 and comparators 

S. Heller, E. Marrer, M.G.P. Page, S. Shapiro, 

L. Thenoz (Basle, CH) 

P676 Emergence and dissemination of 

glycopeptide- and high-level quinupristindalfopristin 

resistant Enterococcus faecium 

clones in various wards of a tertiary hospital 

S. Pournaras, M. Kanellopoulou, A. Ikonomidis, 

E. Papafrangas, A.N. Maniatis (Larissa, Athens, GR) 

P677 Evidence of reserpine-affected mechanism 

of resistance to tetracycline in Neisseria 

gonorrhoeae clinical isolates 

J. Ruiz, A. Ribera, A. Jurado, F. Marco, 

M.T. Jiménez de Anta, J. Vila (Barcelona, E) 

P678 Distribution of ermA, ermC, msrA and linA 

genes in methicillin-resistant staphylococci 

in the Czech Republic 

G. Novotna, J. Janata, J. Spizek (Prague, CZ) 


P679 Fluoroquinolone-selected resistance among 

Pseudomonas aeruginosa: impact on 

susceptibility to imipenem, ertapenem, and 

meropenem 

P. Lister, A. Hossain, J.A. Black, E. Smith-Moland, 

N.D. Hanson (Omaha, USA) 

P680 High prevalence of macrolide resistance 

in Streptococcus mitis from neutropenic 

patients 

W. Achour, O. Guenni, B. Malbruny, A. Canu, 

R. Leclercq, A. Ben Hassen (Tunis, TN) 

P681 Frequency and stability of mutants selected 

with fluoroquinolones from Klebsiella 

pneumoniae containing the plasmid-mediated 

resistance determinant QNR 

J.M. Rodriguez-Martinez, A. Pascual, I. Garcia, 

E. Jiménez-Mejias, J. Pachón, L. Martínez- 

Martínez (Seville, E) 

P682 Resistance mechanisms of fluoroquinoloneresistant 

clinical isolates of Streptococcus 

pneumoniae collected in Belgium, 1999–2003 

S. De Craeye, R. Vanhoof, N. Celio, S. Damée, 

E. Vanbossuyt, J. Content (Brussels, B) 

P683 Inducible metronidazole resistance in nimpositive 

clinical Bacteroides fragilis group 

strains 

M. Hedberg, H. Fang, C. Edlund (Stockholm, S) 

P684 Diversity of the mechanisms involved in 

imipenem resistance in Acinetobacter 

baumannii 

S. Bourdon, M.L. Joly-Guillou (Angers, F) 

P685 Cross-resistance between voriconazole and 

fluconazole due to the expression of efflux 

pumps 

S. Costa-de-Oliveira, C. Pina-Vaz, A. Gonçalves 

Rodrigues (Porto, P) 

P686 Substrate inhibition of the Pseudomonas 

aeruginosa metallo-beta-lactamase, SPM-1, 

in acidic and alkaline conditions 

T.A. Murphy, J. Spencer, R.N. Jones, T.R. Walsh 

(Bristol, UK; North Liberty, USA) 

P687 Class 1 and class 2 integrons among ESBL 

and non-ESBL Escherichia coli isolates 

recovered from nosocomial and community 

environments 

E. Machado, R. Cantón, J.C. Galán, A. Rollán, 

L. Peixe, F. Baquero, T.M. Coque 

(Madrid, Porto, E) 

P688 Induction of the Acinetobacter baumannii 

RND efflux pump AdeB with ciprofloxacin and 

gentamicin 

H. Seifert (Cologne, D)


P689 Detection of carbapenemases in 

Pseudomonas aeruginosa clinical isolates 

resistant to imipenem 

E. Sevillano, M.J. Canduela, A. Umaran, 

F.E. Calvo, L. Gallego (Bilbao, E) 

P690 Non-enzyme-mediated imipenem resistance 

in a clinical isolate of Citrobacter freundii 

from Trondheim, Norway 

M. Castanheira, B. Haldorsen, A. Sundsfjord, 

T. Jacobsen, J. Afset, T. Walsh 

(Bristol, UK; Tromso, Trondheim, N) 

P691 Extended spectrum beta-lactamase (ESBL) 

producers among enterobacteriaceae from 

patients in Bulgarian hospitals 

R. Markovska, E. Keuleyan, M. Sredkova, 

D. Ivanova, B. Markova, P. Sotirova, E. Dragijeva, 

T. Kostyanev, I. Mitov 

(Sofia, Pleven, Stara Zagora, BG) 

P692 Temporal trends of Streptococcus 

pneumoniae isolates with dual resistance to 

beta-lactam and macrolide antibiotics 

J. Fuller, J. Powis, P. Tang, K. Green, D. Low 

and the Canadian Bacterial Surveillance Network 

P693 CdeA of Clostridium difficile, a new multidrug 

efflux transporter of the MATE family 

J. Tankovic, L. Dridi, F. Barbut, D. Decré, 

J.-C. Petit (Paris, F) 

P694 First appearance of the CfiA metallo-betalactamase 

gene in Norway and its association 

with a novel insertion element 

M. Toleman, A. Sundsfjord, A. Onken, 

B. Haldorsen, T. Walsh 

(Bristol, UK; Tromso, Oslo, N) 

P695 Molecular analysis of linezolid resistance in 


T.A. Wichelhaus, S. Besier, V. Brade, A. Ludwig 

(Frankfurt am Main, D) 

P696 Characterisation of the first CTX-M14producing 

Salmonella enterica serotype 

Enteritidis isolate 

L. Romero, L. López, L. Martínez-Martínez, 

B. Guerra, J.R. Hernández, A. Pascual 

(Seville, E; Berlin, D) 

P697 OmpK37 and reduced susceptibility to 

imipenem and meropenem in Klebsiella 

pneumoniae 

H. Segal, B.G. Elisha (Cape Town, ZA) 

P698 In vitro sequential development of gene 

mutations in fluoroquinolone-resistant 

salmonellae 

J.M. Ling, Y. Jin (Hong Kong, HK) 

P699 Biochemical characterisation of IMP-16, 

a novel IMP variant harboured in a class I 

integron of a Pseudomonas aeruginosa 

clinical isolate from Brazil 

R.E. Mendes, M.A. Toleman, H.S. Sader, 

R.N. Jones, T.R. Walsh 


13:00–14:00 

Molecular bacteriology: detection and 

identification of agents 

P700 Pyrosequencing at the Health Protection 

Agency, UK 

C. Arnold, S.E. Gharbia (London, UK) 

P701 Universal 16S rDNA PCR and sequencing in 

the diagnosis of infective endocarditis directly 

from heart valve tissue 

M. Marín, P. Muñoz, M. Rodriguez-Créixems, 

L. Alcalá, J. Silva, E. Bouza – 

Endocarditis Study Group, Madrid, Spain 

P702 Clinical importance of PCR diagnosis in 

bacterial meningitis and sepsis 

S. Plisek, L. Pliskova, V. Dostal, V. Stepanova, 

E. Pozlerova, J. Blazkova (Hradec Kralove, CZ) 

P703 A new scoring method for molecular 

diagnostic kit users 

H. Staines, P. Wallace, R. Pogathota, E. Buultjens 

(Dundee, Glasgow, UK) 

P704 Application of TaqMan probes in end-point 

fluorimetry for detection of pathogenic 

bacteria by polymerase chain reaction 

K. Oravcová, E. Kaclíková, T. Kuchta (Bratislava, SK) 

P705 Usefulness of the MicroSeq 500 16S rDNAbased 

method for identification of bacterial 

isolates unidentified by commercial 

automated systems 

C. Fontana, M. Favaro, M. Pelliccioni, 

E.S. Pistoia, C. Favalli (Rome, I) 

P706 Facts, feasibility and future of bacterial load 

of bloodstream infections 

R.P.H. Peters, T. Schuurman, R.F. de Boer, 

A.M.D. Kooistra, S.A. Danner, 

C.M.J.E. Vandenbroucke-Grauls, 

M.C.J. Persoons, A.A. van Zwet, 

P.H.M. Savelkoul, M.A. van Agtmael 

(Amsterdam, Groningen, NL) 


page 79


P707 Broad-range polymerase chain reaction based 

bacterial and fungal molecular assays improve 

the diagnostic ability of the Duke scheme 

in suspected cases of infective endocarditis 

M. Slany, M. Grijalva, J. Cerny, T. Freiberger 

(Brno, CZ) 

P708 Direct detection of the most important 

bacterial pathogens from blood cultures using 

nucleic acid based techniques 

U. Eigner, M. Weizenegger, M. Holfelder, 

A.-M. Fahr (Heidelberg, D) 

P709 Development of a multiplex real-time PCR 

for detection and differentiation of 

Chlamydiaceae species which are pathogenic 

for humans 

I. Edelstein, A. Narezkina, M. Edelstein 


P710 Detection of Chlamydia trachomatis and 

Neisseria gonorrhoeae in Tripath SurePath 

Pap samples using the Gen-Probe 

Incorporated APTIMA® Combo 2 Assay 

R. Johnson, R. Pilla, M. Alvarez, M. Shih, C. Eng, 

B. Weinbaum (San Diego, USA) 

P711 Detection of Chlamydia trachomatis and 

Neisseria gonorrhoeae in Cytyc Preservcyt ® 

Pap samples using the Gen-Probe 

Incorporated APTIMA® Combo 2 Assay 

R. Johnson, R. Pilla, M. Alvarez, M. Shih, C. Eng, 

B. Weinbaum (San Diego, USA) 

P712 Chlamydophila pneumoniae-specific mRNA 

is present in aortic wall biopsies of patients 

suffering from stable or unstable angina 

pectoris 

M. Edvinsson, E. Hjelm, S. Thelin, G. Friman, 

C. Nyström-Rosander (Uppsala, S) 

P713 Rapid identification of HACEK group of 

bacteria by 16S rRNA gene PCR and restriction 

fragment length polymorphism analysis 

Y. Kodama, M. Sasaki, S. Tajika, Y. Ohara-Nemoto, 

C. Yamaura, Y. Shimoyama, S. Kimura (Morioka, JP) 

P714 Same day molecular diagnostic test result for 

atypical and difficult to grow respiratory 

pathogens including M. tuberculosis complex 

by combining automated DNA extraction 

with real-time PCR 

K. Jaton, C. André, A. Wenger, G. Prod'hom, 

J. Bille (Lausanne, CH) 

P715 Reliable and rapid detection of clinically 

relevant Mycobacterium and Nocardia species 

using a multilex-PCR with genus- and speciesspecific 

primers 

A. Roth, O. Landt, S. Andrees, H. Mauch (Berlin, D) 


P716 Identification of Mycobacterium gordonae 

clinical isolates with the use of four molecular 

methods 

F. Kontos, M. Maniati, Z. Gitti, E. Petinaki, 

P. Papageorgiou, S. Anagnostou, S. Kanavaki, 

S. Nikolaou, C. Kostopoulos, I. Tselentis, 

A.N. Maniatis (Larissa, Crete, Athens, GR) 

P717 Evaluation of the BD ProbeTec ET 

Mycoplasma pneumoniae amplified DNA 

assay 

S.S. Nielsen, S.A. Uldum, B. Dohn, J.S. Jensen 

(Copenhagen, DK) 

P718 Quantification of Salmonella by 5'-nuclease 

polymerase chain reaction targeted to fimC 

gene 

E. Kaclíková, D. Pangallo, T. Kuchta (Bratislava, SK) 

P719 Experiences with Chlamydia testing using 

the BD ProbeTecET and BD Viper focusing on 

inhibition in urine samples 

G. Lisby, H. Westh (Hvidovre, DK) 

P720 Development of a PCR test-system to detect 

the DNA of Bacillus anthracis (pXO1 and 

pXO2) by using a hybridisation method for 

considering amplification results 

O.V. Shevchenko, Y.N. Ilyina, Y.A. Plotnikova, 

A.N. Kulichenko, V.M. Govorun, V.V. Kutyrev 

(Saratov, Moscow, RUS) 

P721 Early diagnosis of leptospirosis by 

polymerase chain reaction 

S. Mitka, D. Karabaxoglou, H. Chaidouli, 

D. Arvanitis, S. Sotiriadis, P. Mamasi, 

A. Kansouzidou (Thessalonica, GR) 

P722 Rapid detection and identification of 

Aspergillus spp. and Candida spp. by 

real-time PCR 

M. Torres, J. Aznar, E. Martín, M. Ruiz, 

M. Ramirez, J. Palomares (Seville, E) 

P723 Molecular genetic identity of blood and oral 

isolates of viridans streptococci 

J. Dusˇková, Z. Broukal, T. Janatová, G. Novotná, 

J. Janata (Prague, CZ)


13:00–14:00 

Molecular bacteriology for Helicobacter pylori 

P724 cagA, vacA and babA2 genotypes of 

Helicobacter pylori strains from patients 

with gastritis or peptic ulcer in Spain 

J.A. García-Campos, D. Domingo, T. Alarcón, 

E. Aznar, J. Díaz-Regañón, M. López-Brea 

(Madrid, E) 

P725 FISH detection of clarithromycin-resistant 

Helicobacter pylori cells in clinical and 

wastewater samples 

P. Piqueres, Y. Moreno, A. Jimenez, 

J. Hernández, M. Ferrús (Valencia, E) 

P726 Effect of the therapy of patients with 

H. pylori related gastritis is correlated with 

organisation of CAG pathogenicity island 

V. Simanenkov, D. Bovaeva, O. Solovjova, 

A. Suvorov (St.Petersburg, RUS) 

P727 AP-PCR genotyping of clinical isolates of 

Pseudomonas aeruginosa 

D.H. Binnet, G. Uraz, E. Senol, N. Akar 

(Ankara, TR) 

P728 Pseudomonas aeruginosa – microarray 

for rapid determination of antibiotic 

susceptibility and virulence factors 

J. Weile, M. Susa, T. Bachmann, C. Knabbe 

(Stuttgart, D) 

P729 Phenotypic and genotypic analysis of 

Pseudomonas aeruginosa strains isolated 

from cystic fibrosis patients 

S. Scutera, T. Allice, S. Bianco, M.G. Chirillo, 

M. Zucca, D. Savoia (Orbassano, I) 

P730 Construction of unmarked mutants in gene 

coding for Ser/Thr protein kinases and 

phosphoprotein phosphatase of 

Pseudomonas aeruginosa and analysis of 

their properties 

J. Nedvedova, P. Lnenicka, K. Hercik, P. Branny 

(Prague, CZ) 

P731 Application of real-time PCR assay to detect 

fragments of the Clostridium botulinum types 

A, B and E neurotoxin genes for public health 

microbiology 

D. Akbulut, K. Grant, M.M. Brett, J. McLauchlin 

(London, UK) 

P732 Evaluation of variable number tandem 

repeats (VNTRs) polymorphisms for 

genotyping “Rickettsia conorii complex” 

strains 

L. Vitorino, R. De Sousa, L. Zé-Zé, F. Bacellar, 

R. Tenreiro (Lisbon, P) 

P733 Monitoring the ability of the human intestinal 

microflora to become re-established after 

antibiotic treatment using T-RFLP 

C. Jernberg, Å. Sullivan, C. Edlund, J. Jansson 

(Huddinge, Stockholm, S) 

P734 Exploring the potential for the rapid 

identification of Campylobacter species using 

MALDI-TOF mass spectrometry 

D.J. Dare, H. Sutton, C. Keys, H. Shah, M. Lunt, 

G. Wells (Manchester, London, UK) 

P735 Application of 23S-5S intergenic spacer 

sequencing for the detection and molecular 

differentiation of Legionella species 

F. Grattard, C. Ginevra, S. Riffard, A. Ros, 

J. Etienne, B. Pozzetto (Saint-Etienne, F) 

P736 Cerebral Whipple’s disease diagnosed by PCR. 

The first case reported from Greece 

M. Papdopoulou, M. Rentzos, V. Ioannidou, 

A. Ioannidis, C. Nicolaou, S. Chatzipanagiotou 

(Athens, GR) 

P737 Corynebacterium amycolatum ATCC 49368 

reference strain is atypical for clinical 

Corynebacterium amycolatum isolates with 

respect to biochemical properties, fatty acid 

analysis and DNA analysis 

K. Martienssen, A. Becker, D.H. Forster, K. Pelz, 

A. Sander, E. Kniehl (Karlsruhe, Freiburg, D) 

P738 Detection of mutations associated with 

resistance to tetracycline and clarithromycin 

in Helicobacter pylori using the 

Pyrosequencer 

A. Lawson, C. Arnold, R. Owen (London, UK) 

P739 Detection of Helicobacter pylori infection by 

ELISA and Westernblot techniques and 

evaluation of anti CagA seropositivity in adult 

dyspeptic patients 

N. Sen, Ö. Yilmaz, A.A. Küpelioglu, I. Simsek 

(Izmir, TR) 

P740 Susceptibility of Helicobacter pylori isolates 

to the anti-adhesion activity of a highmolecular-weight 

constituent of cranberry 

H. Shmuely, O. Burger, I. Neeman, J. Yahav, 

Z. Samra, Y. Niv, N. Sharon, E. Weiss, M. Tabak, 

A. Athamna, I. Ofek (Petach Tiqva, Haifa, 

Rehovot, Jerusalem, Kfar Qaraa, Tel Aviv, IL) 

P741 Helicobacter pylori infection in Venezuela. 

Public health problem 

M.E. Cavazza Porro, M. Correnti, M.I. Urrestarazu, 

J. Vivas, M.E. Avila, D. Ortiz, V. Lecuna, R. Piñero, 

M. Perrone (Caracas, San Cristóbal, VE) 


page 81


P742 Primary antibiotics susceptibility of 

Helicobacter pylori in a general hospital 

N. Montiel, J.M. Navarro, J.L. Prada, 

J. De La Torre, A. Del Arco, C. De Sola, I. Lopez 

(Marbella, E) 

P743 The prevalence and consequences of 

antibiotic resistance in Danish H. pylori 

strains isolated with an interval of 10 years 

S. Hartzen, H. Colding (Charlottenlund, 

Copenhagen, DK) 

P744 Prevalence of Helicobacter pylori resistance 

to clarithromycin in Turkey 

F. Can, M. Demirbilek, H. Selcuk, H. Arslan, 

S. Boyacioglu (Ankara, TR) 

P745 Low seroprevalence of anti-Cag A in spite 

of high seroprevalence of anti-H. pylori 

antibodies in a rural Egyptian community 

S. Zakaria, E. El Sherbini, M. El Raziki, 

S. Saad El Din, M. Mubarak, R. Salama, S. Zakaria 

(Cairo, Giza, EGY) 

13:00–14:00 

ESBL and metallo-beta-lactamases – I 

P746 Extended-spectrum beta-lactamases 

detection in the clinical microbiology 

laboratory 

H. Moraitou, I. Galani, S. Kanavaki, S. Karabela, 

M. Makarona, L. Choraiti, H. Giamarellou 

(Athens, GR) 

P747 Rapid genotyping of the ESBL TEM betalactamases 

using DNA-microarrays 

V. Jung, S. Ezaki, M. Susa, C. Knabbe, R. Schmid, 

T. Bachmann (Stuttgart, D) 

P748 A simple, relevant and cost-effective ESBL 

testing protocol for a routine clinical 

microbiology laboratory: a tertiary care 

hospital study 

A. Guleri, S.R. Alcock, G.D. Corcoran, 

S. Samavedam, J. Robinson, J. Wilson 

(Glasgow, UK) 

P749 Characterisation of Enterobacteriaceae 

producing extended-spectrum beta-lactamase 

enzymes in Scotland 

F.M. MacKenzie, A. Leslie, I.M. Gould 



P750 Occurrence and transferability of beta-lactam 

and aminoglycoside resistance in clinical 

isolates of the family Enterobacteriaceae 

obtained from different wards of a hospital 

in Nitra (Slovakia) 

M. Vrabelova, P. Dianiskova, D. Michalkova- 

Papajova, A. Liskova, M. Kettner 

(Bratislava, Nitra, SK) 

P751 Clinical effectiveness of cefepime in case of 

third-generation cephalosporins treatment 

failure in nosocomial infections caused by 

Enterobacteriaceae producing extendedspectrum 

beta-lactamases 

O. Romashov, S. Yakovlev, S. Sidorenko, 

A. Berezin (Moscow, RUS) 

P752 High prevalence of CTX-M type extendedspectrum 

beta-lactamases in members of 

Enterobacteriaceae in Turkey 

Z. Gulay, G. Terek, B. Eraç, Ç. Bal, D. Gur, 

I. Köksal, C. Ozakin, M. Ozinel, B. Sumerkan 

(Izmir, Istanbul, Ankara, Trabzon, Bursa, Kayseri, TR) 

P753 Prospective evaluation of carriage and 

colonisation with extended-spectrum betalactamase 

producing Enterobacteriaceae 

among newly admitted patients in medical 

departments 

B. Rudensky, D. Raveh, E. Zartzer, E. Broidie, 

A.M. Yinnon (Jerusalem, IL) 

P754 Extended-spectrum beta-lactamases in 

isolates of Enterobacteriaceae from inpatients 

and outpatients in Northern Italy 

F. Luzzaro, M. Perilli, E. Dell'Amico, S. Stefani, 

G.M. Rossolini, G. Amicosante, A. Toniolo 

(Varese, L'Aquila, Siena, Catania, I) 

P755 CTX-M is the dominating extended-spectrum 

beta-lactamase type in Norwegian clinical 

ESBL-producing isolates of Escherichia coli 

and Klebsiella pneumoniae 

S. Tofteland, B. Haldorsen, K. Dahl, G. Simonsen, 

M. Steinbakk, T. Walsh, A. Sundsfjord (Tromsø, 

Akerhus, N; Bristol, UK) 

P756 Simultaneous, bi-clonal outbreak of urinary 

tract infection by E. coli O25 strains with 

CTX-M-15: community and hospital effects in 

2 English health districts 

R. Warren, A. Doroshenko, R. Carr, D. Patel, 

P. O'Neill, G. Harvey, A. Pearson, N. Woodford, 

J. Turton, E. Ward, T. Cheastey, D. Livermore, 

C. Munday, V.M. Ensor, P. Hawkey 

(Shrewsbury, Colindale, Birmingham, UK)


P757 Increased incidence of ESBL in ICU isolates 

from West Midlands region, UK 

V.M. Ensor, C.J. Munday, W-E. Liu, P.M. Hawkey 

(Birmingham, UK) 

P758 Molecular characterisation of Escherichia coli 

isolates producing CTX-M-15 extended-spectrum 

beta-lactamase in the United Kingdom 

N. Woodford, E. Ward, M.E. Kaufmann, 

J. Turton, A. Pearson, S. Harry, R.E. Warren, 

D.M. Livermore (London, Shrewsbury, UK) 

P759 The prevalence of ESBL producing E. coli and 

Klebsiella strains in Copenhagen, Denmark 

A. Kjerulf, D.S. Hansen, N. Frimodt-Møller 

(Herlev, Copenhagen, DK) 

P760 Emergence of ESBL-producing E. coli and 

antimicrobial use in a Spanish region 

A. Yagüe, D. Sandvang, J.-C. Rodríguez, G. Royo, 

N. Gonzalo, A. García-Monsalve, P. Campillos, 

D. Monnet, J.-M. López-Lozano 

(Orihuela, E; Copenhagen, DK; Elche, E) 

P761 Risk factors for community-acquired 

infections due to Escherichia coli harbouring 

extended-spectrum-beta-lactamases 

V. Romani, E. Calbo, C. Garcia-Vidal, L. Gomez, 

M. Xercavins, C. Estrada, L. Lopez-Yeste, 

S. Quintana, J. Garau (Terrassa, E) 

P762 Emergence of CTX-M-type enzymes in 

hospital- and community-acquired isolates 

of Escherichia coli from Northern Italy 

G. Brigante, F. Luzzaro, M. Perilli, G. Lombardi, 

G.M. Rossolini, G. Amicosante, A. Toniolo 

(Varese, L'Aquila, Siena, I) 

P763 First detection of Escherichia coli and 

Klebsiella pneumoniae clinical isolates 

producing acquired beta-lactamases of 

the CMY-LAT lineage in Italy 

L. Pagani, M.M. D'Andrea, R. Migliavacca, 

E. Dell'Amico, M. Spalla, E. Nucleo, G.M. Rossolini 

(Pavia, Siena, I) 

13:00–14:00 

Enteropathogens 

P764 Dissemination of sulphonamide resistance 

genes: first sul3 found in Salmonella from 

Portugal 

P. Antunes, J. Machado, J.C. Sousa, L. Peixe 

(Porto, Lisbon, P) 

P765 Characterisation of beta-lactamase 

production in Salmonella from Portugal 

P. Antunes, J. Machado, J.C. Sousa, L. Peixe 

(Porto, Lisbon, P) 

P766 Increasing incidence of Salmonella typhii with 

reduced susceptibility to ciprofloxacin in 

Kuwait 

A.A. Dashti, P.W.J. West, D. Panigrahi 

(Suleibikhat, KWT) 

P767 Comparison of antimicrobial resistance in 

diarrhoeagenic Escherichia coli isolates 

causing traveller’s diarrhoea between two 

periods, 1994 to 1997 and 2001 to 2003 

E. Mendez Arancibia, J. Ruiz, R. Cabrera, 

J. Gascon, J. Vila (Barcelona, E) 

P768 Increasing fluoroquinolone resistance in 

Salmonella isolates in Finland 

A.J. Hakanen, S. Pitkänen, A. Siitonen, 

P. Kotilainen, J. Jalava, P. Huovinen 

(Turku, Helsinki, FIN) 

P769 Bacteraemia caused by ESBL-producing 

Salmonella enterica serovar. virchow 

6.7:r:1,2 – a cause for concern 

A. Guleri, G.D. Corcoran, S.R. Alcock, D.J. Brown 

(Glasgow, UK) 

P770 The first outbreak of Shiaga toxin producing 

Escherichia coli (STEC) in Korea: 

molecular-epidemiological approach 

S. Kim, Y. Kim, M. Park, J. Kim, S. Jeon, H. Jang, 

S. Kim, S.G. Chun, S. Kim, J.-H. Kim, J. Koo, 

Y. Kang, J. Lee, P. Park, J. Hur, Y. Kim, B. Lee 

(Seoul, Suwon, KOR) 

P771 Epidemiology of antibiotic resistance of nontyphoidal 

Salmonella isolates originating 

from non-human sources during an 11-year 

period in Greece 

A. Markogiannakis, E.N. Velonakis, L. Kondyli, 

M. Mouroutsou, M. Katramadou, M. Lampiri, 

M. Passiotou, A. Bethimouti, A.C. Vatopoulos 

(Athens, Halkis, GR) 

P772 Serotypes and antibiotic resistance patterns 

of Salmonella species isolates in the province 

of South-Kivu, Democratic Republic of Congo 

N. Zozo, O. Vandenberg, B. Bisimwa, A. Dediste, 

P. Donnen, G. Zissis, J. Butzler 

(Bukavu, CD; Brussels, B) 

P773 Antimicrobial resistance of human nontyphoidal 

Salmonella in Ankara, Turkey 

I. Mumcuoglu, N. Balaban, I. Baran, Z.C. Karahan, 

V. Yetener, H. Bodur (Ankara, TR) 

P774 Epidemiology and antimicrobial resistance 

of Shigella spp. in Ankara, Turkey during a 

9-year period (1992-2000) 

N. Balaban, I. Mumcuoglu, A. Ulusoy, 

N. Hayirlioglu, V. Yetener, H. Bodur (Ankara, TR) 


page 83


P775 Antimicrobial resistance in Salmonella and 

Shigella strains isolated from stool cultures 

over a 2-year period in Kocaeli, Turkey 

S. Günde, H. Üçkarde, A. Willke (Kocaeli, TR) 

P776 Transmission and antibiotic resistance 

of Campylobacter sp. in a poultry 

slaughterhouse 

J. Posch, W. Sixl, G. Wüst, S. Schmidt, 

F.F. Reinthaler, G. Feierl, E. Marth (Graz, A) 

P777 Resistance of Shigella spp. in different 

regions of Russia 

O. Kretchikova, A. Ivanov, M. Sukhorukova, 

L. Stratchounski (Smolensk, RUS) 

P778 Campylobacter jejuni and C. coli resistance in 

humans, poultry products and farm chickens: 

an epidemiological and laboratory study 

S. Uzunovic-Kamberovic, T. Zorman, L. Herman, 

I. Berce, S. Smole-Mozina (Zenica, BIH; Ljubljana, SI; 

Melle, B; Nova Gorica, SI) 

13:00–14:00 

Linezolid and glycopeptides in Gram-positive 

bacterial infection 

P779 Oral linezolid as alternative therapy in 

patients with cellulitis referred to an infusion 

centre 

G. Stein, S. Schooley, V. Kak (East Lansing, USA) 

P780 Gram-positive bacteria from diabetic foot 

ulcers and resistance to second-line 

antibiotics (glycopeptides, linezolid, 

quinopristin-dalfopristin) in a German 


S. Monecke, S. Vogel, S. Weber 

(Dresden, Hoyerswerda, D) 

P781 Effects of oral linezolid treatment in 


colonisation in cystic fibrosis patients 

A. Molina, R. Del Campo, L. Máiz, H. Escobar, 

F. Baquero, R. Cantón (Madrid, E) 

P782 Successful treatment of methicillin-resistant, 

teicoplanin-heteroresistant Staphylococcus 

aureus prosthetic valve endocarditis with 

linezolid 

M. Souli, K. Pontikis, Z. Chryssouli, K. Orlandou, 

I. Galani, D. Katsala, H. Giamarellou (Chaidari, GR) 

P783 The possible role of linezolid in the control of 


outbreaks 

I. Pulay, D. Varga Szabó, E. Ungvári, K. Kristóf, 

M. Konkoly-Thege (Budapest, HUN) 


P784 Pharmacoeconomic advantages of linezolid 

for the treatment of Gram-positive infections 

D. Nathwani, S. Duttagupta 

(Dundee, UK; New York, USA) 

P785 Linezolid vs glycopeptides for the treatment 

of suspected or known Gram-positive 

infections in critical patients 

F. Alvarez-Lerma, M. Palomar, F. Bobillo, 

V. González, J. Solé, A. Blanco, C. León – 

Study Group for Gram-positive Infections 

P786 Linezolid versus vancomycin for cultureproven 

complicated skin and soft tissue 

infections – trends of subjects enrolled in 

Europe and globally in a global study 

M. Dryden, N. Chaudry, A. Reisman, J. Weigelt 

(Winchester, UK; New York, Milwaukee, USA) 

P787 Effects of oral linezolid treatment in 


colonisation in cystic fibrosis patients 

A. Molina, R. Del Campo, L. Máiz, H. Escobar, 

F. Baquero, R. Cantón (Madrid, E) 

P788 In vitro spectrum of linezolid and other 

agents against clinical isolates of anaerobes 

K. Aldridge, C. Manders, S. Broyles 

(New Orleans, USA) 

13:00–14:00 

Epidemiology of antibiotic susceptibility 

P789 Decline in antimicrobial susceptibilities of 

anaerobic bacteria from the academic 

hospitals in Bloemfontein, South Africa, 

1996–2003 

P.O. Smith, M.N. Janse van Rensburg, M. Theron 

(Bloemfontein, ZA) 

P790 Antimicrobial resistance of enteropathogenic 

E. coli isolated from rabbits in South Italy 

A. Camarda, D. Pennelli, P. Battista, M. Corrente, 

I. Alloggio (Valenzano, I) 

P791 Frequency and antimicrobial susceptibility 

of bacterial pathogens isolated from bloodstream 

infections in haematology-oncology 

patients: results from the Latin America 

SENTRY Antimicrobial Surveillance Program 

(1997–2002) 

S.S. Andrade, A.C. Gales, H.S. Sader, R.N. Jones, 

J.B. Silva, A.C.C. Pignatari and 

The Sentry Participants Group – Latin America


P792 Frequency of occurrence and antimicrobial 

susceptibility profile of pathogens causing 

bloodstream infections in paediatric patients 

from Latin America: report of SENTRY 

Antimicrobial Surveillance Program 

(1997–2002) 

A.C. Gales, S.S. Andrade, H.S. Sader, R.N. Jones, 

S. Silbert, A.C.C. Pignatari and 

The Sentry Participants Group – Latin America 

P793 Frequency of Gram-positive bacterial 

pathogens in bloodstream infections and 

their resistance to antibiotics in the Czech 

Republic 

M. Kolar, T. Latal, B. Heinigeova, N. Bartonikova, 

P. Cermák (Olomouc, Prague, Jindrichuv Hradec, 

Zlin, Hradec Kralove, CZ) 

P794 Trends of Staphylococcus aureus susceptibility 

to antibiotics isolates in a university hospital 

in France, 1997–2002 

L. Gambotti, P. Girardo, C.M. Couris, 

M.E. Reverdy, J. Etienne, P. Vanhems (Lyon, F) 

P795 A map of bacterial frequency and resistance 

in a Greek Region – Corfu Island 

E. Gatsouli, M. Ovrenovits, A. Pasxali, 

A. Tzanavari (Corfu, GR) 

P796 The epidemiology of antibiotic resistance 

M. Heginbothom (Cardiff, UK) 

P797 Antimicrobial resistance among Staphylococcus 

aureus and Escherichia coli isolates in the 

Indonesian population inside and outside 

hospitals 

E.S. Lestari, K. Kuntaman, H.A. Verbrugh 

on behalf of the study group Antimicrobial 

Resistance in Indonesia: Prevalence and 

Prevention (AMRIN) 

P798 Surveillance of invasive bacterial diseases in 

Greenland, Northern Canada, and the U.S. 

Arctic: 2000–2003 

T. Cottle, M. Bruce, J. Butler, D. Parks, T. Tam, 

S. Deeks, K. Jenson, A. Parkinson 

(Anchorage, USA; Ottawa, CAN; Nuuk, GL) 

P799 Region specificity, frequency of occurrence 

and pattern of antimicrobial susceptibility of 

common bacterial infections in central Illinois 

N. Khardori, M. El-Azizi, A. Mushtaq, C. Ball, 

C. Drake, J. Lawhorn (Springfield, USA) 

P800 Antimicrobial resistance surveillance of 

Gram-negative anaerobic bacteria isolated in 

six Greek hospitals 

J. Papaparaskevas, N.J. Legakis, A. Katsandri, 

A. Avlamis – The Hellenic Study Group for 

Gram-Negative Anaerobic Bacteria 

P801 The value of quality control strains in 

susceptibility tests 

K. Huppertz, I. Noll, B. Wiedemann 

and the GENARS group 

P802 Lack of evidence for DNA in antibiotic 

preparations as a source of antibiotic 

resistance genes 

S.K.P. Lau, P.C.Y. Woo, A.P.C. To, A.T.K. Lau, 

K.Y. Yuen (Hong Kong, HK) 

13:00–14:00 

Enterococci and other Gram-positive bacteria 

P803 Molecular-biology analysis of vancomycinresistant 

enterococci isolated from 

community in the Czech Republic 

M. Kolar, L. Cekanova, I. Vagnerova, 

M. Kesselova, P. Sauer, D. Koukalova, P. Hejnar 

(Olomouc, CZ) 

P804 Prevalence and resistance genotypes of 

glycopeptide-resistant enterococci from 

human and animal sources in Styria, Austria 

A. Eisner, W. Sixl, G. Feierl, J. Koefer, 

G. Gorkiewicz, A.J. Grisold, E. Marth (Graz, A) 

P805 Species distribution and antibiotic resistance 

patterns of glycopeptide-resistant enterococci 

from food-producing animals in Styria, Austria 

A. Eisner, W. Sixl, G. Feierl, J. Koefer, 

G. Gorkiewicz, A.J. Grisold, E. Marth (Graz, A) 

P806 Incidence and in vitro antibiotic resistance of 

streptococci in urinary tract infections 

E. Ikonomopoulou, S. Andreatou, T. Podimatas, 

I. Katsarou, K. Papadopoulos, A. Kolotouros, 

A. Regli (Patras, Zante, GR) 

P807 Emergence of Enterococcus faecium clinical 

isolates resistant to quinupristin/dalfopristin 

F. Kolonitsiou, E. Petinaki, M. Maniati, 

G. Dimitracopoulos, I. Spiliopoulou 

(Patras, Larissa, GR) 

P808 Patterns of antimicrobial resistance in 

nosocomial strains of Enterococcus spp. 

isolated from patients with UTI in different 

parts of Russia 

V. Kretchikov, L. Stratchounski, A. Dekhnich, 

G. Reshedko (Smolensk, RUS) 

P809 Dynamic population evolution of enterococcal 

intestinal carriage during ICU admittance 

P. Ruiz-Garbajosa, V. Pintado, F. Baquero, 

R. Cantón, R. Del Campo (Madrid, E) 


page 85


P810 Community-acquired urinary tract infection 

caused by vancomycin-resistant Enterococcus 

faecalis clinical isolate 

E. Aznar, T. Alarcón, B. Buendía, E. García- 

Peñuela, E. Escudero, M. López-Brea (Madrid, E) 

P811 Detection of vanB2-containing Enterococcus 

faecium strains with the same PFGE clonal 

type in two Spanish hospitals 

A. Portillo, S. Escobar, L. Torres, A. Rezusta, 

M.J. Revillo, C. Aspiroz, F. Ruiz-Larrea, C. Torres 

(Logrono, Zaragoza, E) 

P812 Molecular epidemiology of haematology 

wards-related VRE in Poland 2002–2003: 

from epidemic to endemic 

M. Kawalec, R. Ziolkowski, T. Ozorowski, 

J. Kedzierska, M. Baran, W. Hryniewicz 

(Warsaw, Poznan, Cracow, PL) 

P813 Local engineering and the evolution of an 

Enterococcus faecalis clone in three 

Portuguese cities during a 7-year period 

(1996–2002) 

C. Novais, T.M. Coque, F. Baquero, J.C. Sousa, 

L. Peixe and The Enterococci Study Group 

P814 High diversity of Tn1546 among vancomycinresistant 

enterococci from Portuguese 

human, animal and environmental sources 

C. Novais, T.M. Coque, J.C. Sousa, F. Baquero, 

L. Peixe (Porto, P; Madrid, E) 

P815 Bactericidal activity of daptomycin against 

European staphylococci and enterococci 

A. Fluit, A. Florijn, S. de Vaal, J. Verhoef, 

D. Milatovic (Utrecht, NL) 

P816 Biofilm production and antibiotic resistance 

of human and veterinary Staphylococcus 

strains 

V. Cuteri, L. Bastianini, F. Panzarella, 

M. Marenzoni, A. Attili, C. Pieramati, C. Valente 

(Matelica, Perugia, I) 

P817 Phenotypic characterisation of macrolide 

resistance in S. agalactiae 

Sp. Fokas, St. Fokas, F. Markatou, M. Kalkani, 

M. Dionysopoulou (Sparta, GR) 

P818 Survival of antibiotic-resistant Propioni - 

bacterium acnes in the environment 

A. Qureshi, J.I. Ross, A.M. Snelling, E.A. Eady, 

J.H. Cove (Leeds, Bradford, UK) 


13:00–14:00 

Molecular and clinical virology 

P819 Real-time PCR quantification of enterovirus 

and adenovirus in longitudinal series of stool 

samples from babies at the highest genetic 

risk of type 1 diabetes mellitus 

O. Cinek, P. Drevinek, E. Witso, T. Wetlesen, 

P. Sedlakova, S. Jeansson, K. Ronningen 

(Prague, CZ; Oslo, N) 

P820 Genotypic distribution of Cytomegalovirus 

envelope glycoprotein in different population 

groups in Honduras 

A. Ferrera Boza, M. Arias, N. Tábora, M. Brytting 

(Tegucigalpa, HD; Stockholm, S) 

P821 Prevalence of transfusion transmitted virus 

DNA in serum samples in Austria 

C. Koidl, M. Bozic, R.B. Raggam, J. Berg, 

E. Marth, H.H. Kessler (Graz, A) 

P822 PID-ARI.net and year-round surveillance of 

19 respiratory pathogens in children 

J.A.I. Weigl, W. Puppe, C.U. Meyer, R. Berner, 

J. Forster, F. Zepp, H.J. Schmitt 

on behalf of the PID-ARI.net 

P823 Genotypes of measles virus in Spain during 

2001–2003 

M.M. Mosquera, F. de Ory, J.E. Echevarria 

(Majadahonda. Madrid, E) 

P824 Molecular epidemiology of rotavirus in Korea, 

July 2002 through June 2003: emergence of 

G4P6 and G9P8 strains in two surveillance 

systems 

J.O. Kang, P. Kilgore, J.S. Kim, B. Nyambat, 

J. Kim, H.S. Suh, Y. Yoon, S. Jang, C. Chang, 

S. Choi, M. Kim, J. Gentsch, J. Bresee, R. Glass 

(Guri, Seoul, Jeonju, Gangnung, Daegu, Cheju, 

Gwangju, Busan, Daejun, KOR; Atlanta, USA) 

P825 CMV DNA in plasma and peripheral blood 

leukocytes of healthy CMV-seropositive 

individuals 

K. Midilli, S. Ergin, M. Ozdamar, M. Kuskucu, 

K. Altas (Istanbul, TR) 

P826 Acute cytomegalovirus meningoencephalitis 

in immunocompetent patient 

R. Mauri, A. Tocchetti, E. Rinaldi, E. Sala, 

E. Longoni, D. Santoro (Como, I) 

P827 Epstein-Barr virus and gastric carcinoma: 

the frequency of EBV association and 

quantification of viral DNA 

C. Nogueira, M. Correia Leitão, P. Figueiredo, 

J. Ganho, F. Martinho, C. Gregório, M. Martins, 

T. Lindo, P. Santos, F. Regateiro, A. Magalhães- 

Sant'Ana (Coimbra, P)


P828 External quality assessment for molecular 

detection and quantification of human 

cytomegalovirus DNA in the Belgian centres 

for molecular diagnosis 

F. Brancart, B. Vincart, C. Liesnard 

and the Belgian Centres for Molecular Diagnosis 

( Brussels, B ) 

P829 A simple technique for internal control of 

real-time amplification assays 

S. Burggraf, K. Appel, N. Malik, J. Neumann, 

E. Schuhmacher, B. Olgemöller (Munich, D) 

P830 External quality assessment for the molecular 

detection of viruses in simulated cerebral 

spinal fluid 

V.J. Chalker, Z. Mee, V. James (London, UK) 

P831 EQA programmes in clinical virology and 

microbiology 

C. Forde, C. Scott, C. Steel, P. Wallace, 

A.M. van Loon (Glasgow, UK) 

P832 Nucleic acid isolation using the NucliSens 

mini MAG instrument 

P. van Deursen, A. Verhoeven, P. de Bie, 

A. van Grinsven, M. Jacobs, P. van de Wiel 

(Boxtel, NL) 

P833 Pyrosequencing technology: a novel DNA 

sequencing technique for rapid and reliable 

typing of human papillomaviruses 

B. Gharizadeh, M. Oggionni, B. Zheng, 

N. Pourmand, E. Akom, K. Wallin, P. Nyren 

(Stockholm, S; Milan, I; Palo Alto, USA; Quebec, 

CAN) 

P834 Comparison of the NucliSens Magnetic 

Extraction Reagents to reference extraction 

methods for the isolation of RNA and DNA 

from various sample types 

G. Onland, L. Bartels, P. van Deursen, M. Jacobs, 

C.H.E. Boel, A.J.C. van den Brule 

(Veldhoven, Boxtel, NL) 

P835 Rapid detection of adenovirus DNA in 

conjunctival scrapings by real-time PCR using 

SYBR Green I as the detection dye 

L. Folgueira, C. Prieto, S. Maldonado, M.J. Babiano, 

J.R. Otero (Madrid, E) 

P836 Enterovirus detection by real-time RT-PCR 

in the study of aseptic meningitis 

L. Santos, J. Simões, S. Martins, A. Silvestre, 

R. Costa, J. Freitas Da Fonseca, H. Lecour 

(Porto, P) 

P837 Lack of detection of human retrovirus-5 

(HRV-5) proviral DNA in synovial tissue and 

blood specimens from individuals with 

rheumatoid arthritis or osteoarthritis 

K. Piper, A. Hanssen, D. Lewallen, E. Matteson, 

R. Hagan, J. Steckelberg, R. Patel 

(Rochester, USA) 

P838 Diagnostic of viral infections of central 

nervous system by polymerase chain reaction 

A. Domingos, G. Marrão, C. Nogueira, 

A. Pinto de Oliveira, G. Rocha, 

A. Magalhães-Sant'Ana (Coimbra, P) 

P839 Detection of human cytomegalovirus DNA in 

placenta using PCR 

E. Paradowska, M. Przepiorkiewicz, 

D. Nowakowska, M. Studzinska, J. Wilczynski, 

Z.J. Lesnikowski (Lodz, PL) 

P840 Quantitative real-time PCR for diagnosis of 

VZV infection in cerebrospinal fluid 

E. Zampachova, N. Piskunova 

(Ceske Budejovice, CZ) 

P841 Detection of herpes simplex virus and 

enteroviruses in cerebrospinal fluid by 

real-time PCR 

J. Garcia-Martinez, L. Folgueira, C. Prieto, 

S. Maldonado, M.J. Babiano, J. Otero (Madrid, E) 

P842 Comparison of three commercial glycoprotein 

G-based enzyme immunoassays for detection 

of HSV-1/HSV-2 IgG antibodies in pregnant 

women and sex workers 

A. Aksözek, M. Özdamar, S. Ergin, K. Midilli, 

S. Serdaroglu, S. Türkoglu, G. Yilmaz 

(Istanbul, TR) 

P843 A novel enzyme immunoassay for the 

detection of anti-herpesvirus-8 lytic IgG 

antibodies: evaluation of clinical performance 

characteristics 

F. Loftus, S. O'Keeffe, D. O'Leary, G. Elliott, 

S. Reid (Dublin, IRL) 

P844 A new enzyme immunoassay for the 

detection herpes simplex virus type 2 – 

specific antibodies 

A. Obriadina, S. Klimashevskaya, M. Gladisheva, 

V. Puzyrev, A. Burkov, T. Ulanova 

(Nizhniy Novgorod, RUS) 

P845 Detection of the six commonest human 

herpesviruses in clinical specimens by a 

single PCR (Herpes Consensus methodology) 

S. Levidiotou, G. Vrioni, C. Gartzonika, T. Priavali, 

C. Christaki (Ioannina, GR) 


page 87


P846 Questioning the programmed cell death in 

bovine herpesvirus 1 infected MDBK cells and 

the possible role of nitric oxide in this process 

Z. Yazici, Y. Baskin, H. Baskin, O. Gecer, A. Ozkul, 

I.H. Bahar (Izmir, TR) 

P847 Inversely proportional relation between 

programmed cell death and nitric oxide 

responses: latency behaviour of bovine 

herpesvirus-1 in an epithelial like 

microenvironment 

Y. Baskin, Z. Yazici, H. Baskin, O. Gecer, 

N. Olgun, A. Ozkul, I. Hakki Bahar (Izmir, TR) 

P848 In vitro inhibition of herpes simplex virus type 

1 replication caused by various probiotics 

A. Voeikova, E. Ermolenko, V. Furaeva, 

A. Suvorov (Saint-Petersburg, RUS) 

13:00–14:00 

Clostridium difficile 

P849 Prevalence of Clostridium difficile in 

hospitalised patients 

M. Lemeshevskay, I. Malov, S. Balakhonov, 

K. Aitov, Y. Plotnikhova (Irkutsk, RUS) 

P850 The first report of the occurrence of Car diff- 

PCR – ribotypes among clinical Clostridium 

difficile strains isolated from patients with 

AAD in a university hospital, Warsaw 

H. Pituch, J.S. Brazier, P. Obuch-Woszczatynski, 

D. Wultanska, F. Meisel-Mikolajczyk, M. Luczak 

(Warsaw, PL; Cardiff, UK) 

P851 Risk factors of Clostridium difficile-associated 

diarrhoea due to actin-specific ADP-ribosyl 

transferase producing strains 

F. Barbut, D. Decré, V. Lalande, L. Noussair, 

B. Burghoffer, A. Gigandon, F. Espinasse, 

L. Raskine, J. Robert, A. Mangeol, C. Branger, 

J. Petit (Paris, Clichy, Boulogne, Montfermeil, F) 

P852 Control of an outbreak of Clostridium difficile 

infection among geriatric patients 

S. Cherifi, J. Robberecht, V. Ledeganck, B. Byl, 

M. Delmee, G. Mascart (Brussels, B) 

P853 Toxigenic status of C. difficile in a large 

hospital: classical and molecular approaches 

A. Martín, R. Alonso, T. Peláez, M. Marín, 

M. Rodríguez-Creixems, E. Bouza (Madrid, E) 

P854 An investigation into the carriage of 

Clostridium difficile on the hands of health 

care workers 

S. Maxwell, F. Hudson (Stockport, UK) 


P855 Tolemaver (GT160-246) binds Clostridium 

cytotoxins A/B and is associated with 

restoration of components of the anaerobic 

intestinal microflora during treatment of 

C. difficile-associated diarrhoea 

T. Louie, B. Byrne, J. Emery, W. Krulicki, L. Ward, 

D.R. MacCannell, M. Montgomery, D. Gregson, 

M. Mah (Calgary, CAN) 

13:00–14:00 

Nosocomial infections: nonfermentative 

Gram-negative bacilli – I 

P856 Empirical antimicrobial treatment 

established according to the temporal 

evolution of hospital outbreaks on patients 

with bloodstream A. baumannii infections 

J.J. Camarena, J.C. Navarro, R. González, 

R. Zaragoza, A. Artero, A. Gea, J.M. Nogueira 

(Valencia, E) 

P857 Outbreak of ampicillin-resistant and highlevel 

gentamicin-resistant enterococci 

in paediatric blood-stream infections in a 

tertiary hospital in Tanzania 

B. Blomberg, S.C. Mohn, K.P. Manji, N. Langeland 

on behalf of the joint study group on antimicrobial 

resistance at Muhimbili National Hospital, 

Dar es Salaam, Tanzania and the University of 

Bergen, Norway 

P858 Molecular characterisation of an outbreak 

caused by cefoxitin-resistant Klebsiella 

pneumoniae 

G. Kartali, E. Tzelepi, M. Tsivitanidou, D. Sofianou 

(Thessalonica, Athens, GR) 

P859 Intensive care unit outbreak caused by a 

strain of Acinetobacter baumannii producing 

the PER-1 extended-spectrum ß-lactamase 

S.H. Jeong (Busan, KOR) 

P860 Nosocomial outbreak of Salmonella 

enteritidis in a neonatal unit 

G. Gonzalez Mediero, H. Bello, M. Alvarez, 

I. Otero, I. Iglesias, T. Del Blanco, M. Usera 

(Vigo, Madrid, E) 

P861 Pseudo-outbreak of Pseudomonas aeruginosa 

infections associated with bronchoscopic 

procedures 

F.J. Vasallo, S. Pérez, M.A. Domínguez, 

A. González-Escalada, V. del Campo, J.L. Guerra, 

J. Torres (Vigo, Barcelona, E) 

P862 Outbreak of Klebsiella pneumoniae causing 

fulminant sepsis in a neonatal unit 

R. Alonso, B. Padilla, C. Sánchez-Carrillo, 

E. Cercenado, M. Sánchez-Luna, E. Bouza 

(Madrid, E)


P863 Epidemic ceratoconjunctivitis outbreak at a 

university eye clinic 

A. Willke, L. Kocabas, A. Kubar, S. Erdogan, 

N. Yuksel, S. Gündes, M. Celik, S. Ustacelebi, 

Y. Caglar (Kocaeli, Ankara, TR) 

13:00–14:00 

Catheter-related infections 

P864 Health and economic outcomes of nosocomial 

catheter-related candidaemia in critically ill 

patients 

S. Blot, K. Vandewoude, J. De Waele, E. Hoste, 

J. Deschuijmer, J. Decruyenaere, F. Colardyn 

(Ghent, B) 

P865 Investigation of central intravenous catheterrelated 

bacteraemia 

A. Tarpatzi, I. Stefanou, A. Katsandri, 

J. Papaparaskevas, G. Petrikkos, G.L. Daikos, 

A. Avlamis (Athens, GR) 

P866 Differences in development of catheterrelated 

infections in critically ill adults 

M. Sredkova, V. Edreva, V. Todorov (Pleven, BG) 

P867 Catheter-related sepsis in critically ill and 

associated mortality 

I. Leonard, A. Vandenberghe, P. Laterre (Brussels, B) 

P868 Relationship of catheter-related infections in 

patients with skin and nasal colonisation by 

endemic hospital-acquired oxacillin-resistant 

Staphylococcus epidermidis strains 

D. Blum-Menezes, O.J. Bratfich, M.C. Padoveze, 

M.L. Moretti (Sao Paulo, BR) 

P869 Incidence and risk factors of central venous 

catheter-related bacteraemia in gastrointestinal 

surgical units 

J.-M. Januel, P. Vanhems, C. Chambrier, 

C. Chemorin, E. Tissot, X. Barth, J. Fabry, 

P. Bouletreau, R. Ecochard (Lyon, F) 

P870 Usefulness of a disinfectable needle-less 

connector in the prevention of arterial 

catheter colonisation 

J.C. Yébenes, G. Sauca, G. Miró, J. Almirall, 

R. Martínez, M. Serra-Prat, X. Buquet, X. Balanzó 

(Mataró, E) 

P871 The “antibiotic-lock technique” for eradication 

of “difficult” or multiple micro-organisms in 

infections of long-term central venous 

catheters 

A. Scalzini, G. Gattuso, D. Tomasoni, L. Palvarini 

(Mantua, I) 

P872 Determination of disinfectants' effectiveness 

and their activity to adherent catheter 

bacterial strains isolated in the hospital 

environment 

K.W. Pancer, E. Mikulak, A.E. Laudy, B. Sawicka, 

D. Rabczenko, T. Wernik, A. Gliniewicz, 

H. Stypulkowska-Misiurewicz (Warsaw, PL) 

P873 Propionibacterium acnes is a common 

coloniser of intravascular catheter tips 

P. Martín-Rabadán, L. Alcalá, M. Rodriguez, 


P874 Vascular access site infections in haemodialysis 

patients in Italy: a surveillance study 

L. Scudeller, G. Brunori, N. Petrosillo, 

G. Cancarini, G. Carosi, P. Viale 

(Udine, Brescia, Rome, I) 

13:00–14:00 

Nosocomial infections: I 

P875 Catheter-associated urinary tract infections in 

hospitalised elderly women 

M. Kompoti, A. Mousouli, K. Kontos, 

A. Georgopali, O. Zarkotou, C. Nikolopoulou, 

S. Drimis (Athens, GR) 

P876 Antimicrobial resistance and causative agents 

of nosocomial urinary tract infection in the 

medical wards in a tertiary hospital 

E. Vagiakou-Voudris, A. Kapogli, G. Zorbas, 

A. Strouza, E. Malamou-Lada (Athens, GR) 

P877 Epidemiology of ventriculostomy-related 

infections in neurosurgical patients 

B. Tiodorovic, M. Babic, M. Dinic (Nis, CS) 

P878 Cerebrospinal fluid shunt infections in adults: 

a 15-year experience 

X. Santesmases, A. Pallarés, N. Sopena, 

M. Giménez, M.L. Pedro-Botet, J.M. Cladellas, 

S. Colet, C. Rey-Joly, M. Sabrià (Badalona, E) 

P879 Evaluation of postneurosurgical nosocomial 

meningitis in adults 

C. Bulut, A. Tekiner, M.A. Yetkin, C.A. Hatipoglu, 

Z. Buharali, N. Tulek (Ankara, TR) 

P880 The influence of antimicrobial prophylaxis 

on upper respiratory tract microflora in 

hospitalised patients with resectable lung 

cancer 

U. Kosikowska, R. Los, A. Biernasiuk, M. Juda, 

A. Malm, P. Rybojad, F. Furmanik (Lublin, PL) 


page 89


P881 Aerobic and anaerobic flora isolated from 

pleural drains in patients with lung cancer 

after thoracic surgery 

R. Los, I. Korona-Glowniak, A. Malm, P. Rybojad, 

F. Furmanik (Lublin, PL) 

P882 Severe bacteraemic infections in patients 

with diabetes mellitus 

A. Artero, J.J. Camarena, R. Zaragoza, S. Sancho, 

J. Tamarit, R. González, J. Nogueira (Valencia, E) 

P883 A rare case of brucella infection of an 

obstetrician during the delivery of an infected 

infant 

A. Poulou, F. Markou, X. Efthimiou, F. Mountaki 

(Serres, GR) 

P884 Characterisation and sensitivity of 

coryneforme bacteria isolated in clinically 

significant pictures: a three-year study 

J.L. Gómez-Garcés, A. Alhambra Mosquera, 

J.-I. Alós Cortés (Madrid, E) 

P885 Enterotoxigenic Bacteroides fragilis strains 

isolated from clinical specimens of human 

and animal origin 

P. Obuch-Woszczatynski, A. Rokosz, 

A. Sawicka-Grzelak, H. Pituch, M. Luczak 

(Warsaw, PL) 

P886 Impetigo bullosa at the neonatological and 

obstetrician department – molecular analysis 

J. Jursa, A. Kordek, S. Giedrys-Kalemba 

(Szczecin, PL) 

P887 The potential role of the German cockroach 

(Blatella germanica) in carrying pathogens in 

two general hospitals, Tehran 

K. Holakouie Naieni, H. Ladoni, H. Soliemani, 

S. Afhami, B. Haghighat (Tehran, IR) 

P888 Role of Coxiella burnetii in hospitalised 

patients with atypical pneumonia 

P. Douramani, S. Mavrea, E. Anastasakou 

(Athens, GR) 

P889 Prediction of post-cardiosurgery infectious 

complications by means of procalcitonin 

monitoring 

N. Beloborodova, D. Popov (Moscow, RUS) 

13:00–14:00 

Animal models 

P890 Is multiple trauma accompanied by bacterial 

translocation? An experimental model 

E. Bathrelos, E.J. Giamarellos-Bourboulis, 

N. Efstathopoulos, J. Lazarettos, V. Nikolaou, 

A. Papalois, P. Grecka (Athens, GR) 


P891 Pharmacodynamic conditions of emergence 

and extinction of mutant resistant 

Streptococcus pneumoniae in experimental 

pneumonia treated with moxifloxacin: 

interest of the Mutant Selection Window 

Concept 

M. Etienne, D. Croisier, P. Charles, L. Piroth, 


P892 Pharmacodynamic evaluation of the efficacy 

of a human-like treatment with gatifloxacin 

on experimental pneumococcal pneumonia: 

impact of low levels of resistance 

D. Croisier, M. Etienne, P. Charles, L. Piroth, 


P893 Hearing loss in experimental pneumococcal 

meningitis increases after pretreatment with 

G-CSF 

C. Brandt, S.P. Lund, C. Østergaard, N. Frimodt- 

Møller, F. Espersen, P. Caye-Thomassen, 

J.D. Lundgren (Copenhagen, DK) 

P894 In pneumococcal meningitis adjuvant 

doxycycline improves survival, and reduces 

neuronal injury 

D.N. Meli, D.G. Erhardt, J. Kummer, S.L. Leib 

(Berne, CH) 

P895 In vivo synergism of amoxicillin sub-inhibitory 

concentrations and specific antibodies 

against Streptococcus pneumoniae in a mice 

sepsis model 

J. Casal, M. Giménez, D. Tarragó, A. Fenoll, 

L. Aguilar (Majadahonda Madrid, E) 

P896 Daptomycin is highly efficacious against 

penicillin-resistant and penicillin- and 

quinolone-resistant pneumococci in 

experimental meningitis by sterilising the 

CSF within 4 hours 

P. Cottagnoud, M. Pfister, M. Cottagnoud, 

F. Acosta, L. Flatz, F. Kühn, A. Stucki 

(Berne, CH; San Francisco, USA) 

P897 Moxifloxacin and levofloxacin treatment 

outcomes against pneumococcal pneumonia 

in a novel skin-temperature murine model 

D. Bast, D. Bell, X. Chen, L. Dresser, L. Mandell, 

D. Low, J. de Azavedo (Toronto, Hamilton, CAN) 

P898 Evaluation of fosfomycin in the treatment 

of experimental meningitis caused by a highlevel 

cephalosporin-resistant Streptococcus 

pneumoniae 

S. Ribes, A. Domenech, F. Taberner, C. Cabellos, 

F. Tubau, J. Liñares, P. Fernández Viladrich, 

F. Gudiol (Hospitalet de Llobregat, Barcelona, E)


P899 Combination of linezolid and rifampin is 

highly synergistic in experimental 

Staphylococcus aureus joint prosthesis 

infection 

A. Saleh-Mghir, C. Muller-Serieys, L. Massias, 

A.C. Crémieux (Paris, F) 

P900 Evaluation of lauric acid monoester 

compounds in a Staphylococcus aureus nasal 

decolonisation model 

M. Rouse, M. Scholz, J. Steckelberg, R. Patel 

(Rochester, St. Paul, USA) 

P901 TolC but not AcrB plays an essential role in 

colonisation of chicks with multi-resistant 

Salmonella typhimurium DT104 

S. Baucheron, C. Mouline, K. Praud, 

E. Chaslus-Dancla, A. Cloeckaert (Nouzilly, F) 

P902 Efficacy of cefepime and imipenem in 

experimental pneumonia caused by porindeficient 

Klebsiella pneumoniae producing 

CMY-2 ß-lactamase 

C. Pichardo, J.M. Rodriguez-Martinez, 

M. Herrero, M.-C. Conejo, M. Aguilar, 

L. Martinez-Martinez, J. Pachón, A. Pascual 

(Seville, E) 

P903 Mycobacterium abscessus causes a 

granulomatous infection controled by IFNg 

in C57BL/6 mice 

P. Hochedez, M. Rottman, C. Soudais, 

F. Ripoll, J.-F. Emile, J.-L. Gaillard 

(Garches, Paris, Boulogne Billancourt, F) 

P904 Animal model of Guillain-Barré syndrome by 

sensitisation with a Campylobacter jejuni 

lipopolysaccharide 

P. Gandolfi, M. Luciani, C.M. Caporale, 

G. Armillotta, A. Uncini (Teramo, Chieti, I) 

P905 Campylobacter concisus infection in mice 

R. Aabenhus, Å. Ljungh, U. Stenram, H. Permin, 

L. Andersen (Copenhagen, DK; Lund, S) 

P906 N-6 polyunsaturated fatty acids enhance the 

activity of antimicrobials in experimental 

sepsis by multiresistant Pseudomonas 

aeruginosa 

M. Mouktaroudi, P. Koutoukas, T. Adamis, 

I. Alexandrou, H. Giamarellou, E.J. Giamarellos- 

Bourboulis (Athens, GR) 

P907 Successful management of experimental 

sepsis by Acinetobacter baumannii with the 

co-administration of colistin and rifampin 

A. Pantopoulou, M. Raftogiannis, M. Mouktaroudi, 

I. Dontas, D. Perrea, E. J. Giamarellos-Bourboulis 

(Athens, GR) 

P908 Beta-lactams and aminoglycosides in 

combination for pneumonia by carbapenemresistant 

Acinetobacter baumannii in a mice 

model 

A. Montero, J. Ariza, X. Corbella, A. Domenech, 

S. Ribes, J. Ayats, F. Tubau, F. Gudiol 

(L'Hospitalet, Barcelona, E) 

P909 Cranberry juice and its organic acids inhibits 

E. coli colonization of the bladder in a mice 

model of urinary tract infection 

H.D. Jensen, S.B. Christensen, K.A. Krogfelt 


P910 Correlation between growth rates and murine 

LD90 for a variety of Aspergillus fumigatus 

isolates 

D. Paisley, G. Robson, D. Denning 


P911 Histopathological follow-up of the pancreas 

and small intestines of mice, experimentally 

infected by the oral and intraperitoneal routes 

J. Kovacova, S. Bopegamage, A. Vargova, 

J. Motusova, M. Borsanyiova, A. Petrovicova, 

M. Benkovicova, P. Gomolcak, J. Galama 

(Bratislava, SK; Nijmegen, NL) 

P912 Mouse models of Coxsackie B virus infection: 

comparison of oral and intraperitoneal route 

of infection with follow-up of virus shedding 

in stool and virus replication in the small 

intestine 

A. Vargova, M. Borsanyiova, A. Petrovicova, 

S. Bopegamage (Bratislava, SK) 

P913 Identification of porcine endogenous 

retroviruses in severe combined 

immunodeficient mice and Lewis rats 

xenotransplanted with porcine neonatal 

pancreatic cell clusters 

S. Kim, Y. Kim, J. Sohn, K. Yoon, W. Shin, 

M. Kang (Seoul, KOR) 


page 91

12:00–13:00 

New drugs 

Poster Sessions Monday, May 3, 2004 

P914 Antimicrobial spectrum and activity of NVP 

PDF-713 (PDF7), a novel peptide deformylase 

inhibitor, tested against 1,837 recent Grampositive 

clinical isolates 

R. Jones, T. Fritsche, H. Sader 


P915 Antistaphylococcal activity of NVP-PDF713, a 

new peptide deformylase inhibitor compared 

to other agents 

P. Appelbaum, L. Ednie, M. Jacobs 


P916 Antipneumococcal activity of NVP-PDF713 

compared to 18 other agents 

P. Appelbaum, L. Ednie, M. Jacobs 


P917 Evaluation of the in vitro activity of NVP PDF- 

713 against clinical anaerobic isolates with 

emphasis on the Bacteroides fragilis group 

D.R. Snydman, N.V. Jacobus, L.A. McDermott 

(Boston, USA) 

P918 Potential utility of a peptide deformylase 

inhibitor, NVP PDF-713 (PDF7) against 

oxazolidinone-resistant or streptograminresistant 

Gram-positive isolates 

R. Jones, G. Moet, H. Sader, T. Fritsche 


P919 Time-kill study of antistaphylococcal activity 

of NVP PDF-713 compared to other agents 

P. Appelbaum, K. Credito, G. Lin, M. Jacobs 


P920 Time-kill study of the antipneumococcal 

activity of NVP PDF-713, a new peptide 

deformylase inhibitor, compared to 13 other 

agents 

P. Appelbaum, G. Pankuch, M. Jacobs 


P921 In vivo pharmacodynamics of NVP-PDF-713, 

a new peptide deformylase inhibitor 

W. Craig, D. Andes (Madison, USA) 

P922 In vivo pharmacodynamic activity of NVP- 

PDF-713 against multiple bacterial pathogens 

W. Craig, D. Andes (Madison, Wisconsin, USA) 

P923 Determination of quality control guidelines 

for MIC dilution and disk diffusion methods 

when testing NVP-PDF713, a novel peptide 

deformylase inhibitor 

T. Fritsche, T. Anderegg, R. Jones 



P924 Determination of dry-form commercial 

reagent reproducibility and MIC validations 

for NVP-PDF713, a novel peptide deformylase 

inhibitor 

G. Moet, R. Jones, P. Rhomberg, T. Fritsche 


P925 Activity of BAY 73-7388, a novel aminomethylcycline, 

and other novel antibiotic classes 

against resistant bacteria in vitro 

B. Bhatia, T. Bowser, J. Chen, M. Ismail, 

L. Honeyman, R. Mechiche, M. Nelson, 

K. Ohemeng, A. Verma, K. Tanaka, A. Macone 

(Boston, USA) 

P926 Potent activity of BAY 73-7388, a novel 

aminomethylcycline, against susceptible and 

resistant Gram-positive and Gram-negative 

organisms 

A. Macone, J. Donatelli, T. Dumont, S. Weir, 

S.B. Levy, K. Tanaka (Boston, USA) 

P927 BAY 73-7388, a novel aminomethylcycline, 

exhibits potent efficacy in pulmonary murine 

models of infection 

D. McKenney, J.M. Quinn, C.L. Jackson, 

J.L. Guilmet, J.A. Landry, K. Tanaka, E.P. Cannon 

(Boston, USA) 

P928 BAY 73-7388 is highly efficacious in animal 

models of intra-abdominal infections caused 

by a range of aerobic and anaerobic organisms, 

including VRE 

R. Endermann, C.H. Ladel, H. Broetz-Oesterhelt, 

H. Labischinski (Wuppertal, D) 

P929 BAY 73-7388 demonstrates greater activity 

than linezolid in a range of murine models of 

skin and soft tissue infection 

C.H. Ladel, R. Endermann, H. Broetz-Oesterhelt, 


P930 Superior efficacy of BAY 73-7388, a novel 

aminomethylcycline, compared with linezolid 

and vancomycin in murine sepsis caused by 

susceptible or multiresistant staphylococci 

H. Broetz-Oesterhelt, R. Endermann, C.H. Ladel, 


P931 BAY 73-7388, a novel aminomethylcycline, 

is highly active in vivo in a murine model 

of pneumococcal pneumonia 

R. Endermann, C.H. Ladel, H. Broetz-Oesterhelt, 


P932 Activity of dalbavancin against European 

clinical isolates of staphylococci and 

streptococci 

R. Flamm, D. Draghi, M. Jones, C. Thornsberry, 

J. Karlowsky, D. Sahm (Herndon, USA)


P933 In vitro antistaphylococcal and antistreptococcal 

activity of dalbavancin, assessed by 

British & NCCLS methods 

S. Mushtaq, M. Warner, D.M. Livermore 

(London, UK) 

P934 Efficacy and safety of once-weekly 

dalbavancin vs vancomycin in catheterrelated 

bloodstream infections 

E. Seltzer, M. Wible, B.P. Goldstein, M.B. Dorr, 

T.J. Henkel, R. Darouiche, J. Vazquez, I. Raad 

(King of Prussia, Houston, Detroit, USA) 

P935 Once-weekly dalbavancin in catheter-related 

bloodstream infections: microbiological 

findings 

B.P. Goldstein, R.N. Jones, D.J. Biedenbach, 

E. Seltzer, M.B. Dorr, D. Krause, T.J. Henkel 

(King of Prussia, North Liberty, USA) 

P936 Evaluations of Dalbavancin activity and 

spectrum tested against European isolates 

R. Jones, T. Fritsche, H. Sader 


P937 In vitro activity of the glycylcycline tigecycline 

tested against a worldwide collection of 

10,127 contemporary staphylococci, strepto - 

cocci and enterococci 

T. Fritsche, H. Sader, J. Kirby, R. Jones 


P938 Endemic, highly resistant Acinetobacter in 

the intensive care unit – Is tigecycline the 

answer? 

P. Wilson (London, UK) 

P939 Antimicrobial activity of tigecycline (GAR-936) 

tested against enterobacteriaceae, and 

selected non-fermentative Gram-negative 

bacilli, a worldwide sample 

R. Jones, T. Fritsche, H. Sader, M. Beach 


P940 Activity of tigecycline tested against clinical 

isolates of Haemophilus influenzae, Moraxella 

catarrhalis and Neisseria menigitidis, a 

worldwide perspective 

H. Sader, T. Fritsche, J. Kirby, R. Jones 


12:00–13:00 

Molecular bacteriology: antibiotic susceptibility 

P941 DNA microarray technology for detection of 

beta-lactamase genes in pathogenic bacteria 

M.M. D' Andrea, M. Cassone, T. Giani, 

G. Coratza, G. Pozzi, G.M. Rossolini (Siena, I) 

P942 Multiplex PCR detection of CTX-M type gene 

C.J. Munday, V.M. Ensor, W.E. Liu, P.M. Hawkey 


P943 Differentiation of Citrobacter koseri and 

Citrobacter amalonaticus isolates using betalactamase 

gene sequences 

M. Avison, S. Underwood (Bristol, UK) 

P944 A single-tube PCR with MGB Eclipse probes 

for detection of SHV-type extended-spectrum 

beta-lactamases 

A. Ekimov, M. Edelstein, E. Belousov 

(Smolensk, RUS; Bothell, USA) 

P945 Evaluation of gentamicin disk diffusion 

method for detecting high-level Gentamicinresistant 

Enterococci by comparison with a 

polymerase chain reaction technique 

detecting the aac(6´)-Ie-aph(2´´)-Ia aminoglycoside 

modifying gene 

B. Saeedi, A. Hällgren, B. Isaksson, J. Jonasson, 

L.E. Nilsson, H. Hanberger (Linköping, S) 

P946 Identification of Enterococcus spp. of the 

human normal microbiota by pyrosequencing 

M. Lindgren, P. Huovinen, C. Edlund, J. Jalava 

(Turku, FIN; Stockholm, S) 

P947 Detection of resistance genes of vancomycinresistant 

enterococci by sandwich 

hybridisation method 

V. Skandami, A. Tsiringa, A. Xanthaki, 

M. Toutouza, C. Kontou-Castellanou (Athens, GR) 

P948 Evaluation of the EvigeneTM VRE detection 

kit for detecting of enterococci including 

vancomycin resistance genes 

A. Kilic, M. Baysallar, G. Bahar, 

A. Kucukkaraaslan, L. Doganci (Ankara, TR) 

P949 Development of antibiotic resistance in 

Enterobacteria 

S.D. Nyberg, A. Hakanen, M. Österblad, 

P. Huovinen, C. Edlund, J. Jalava 

(Turku, FIN; Stockholm, S) 

P950 Prevalence and implication of the cfiA and 

cphA genes in imipenem resistance among 

Bacteroides spp. 

M. Theron, M.N. Janse van Rensburg, 

C. Roussouw (Bloemfontein, ZA) 

P951 Identification of Nocardia clinical isolates by 

PCR and restriction analysis and susceptibility 

patterns 

M. Marín, E. Cercenado, P. Martín-Rabadán, 

P. Muñoz, C. Radice, E. Bouza (Madrid, E) 


page 93


12:00–13:00 

Molecular bacteriology: borrelia 

P952 Isolation and identification of Borrelia strains 

from ticks collected in the Czech Republic 

H. Drevová, D. Hulínská, J. Plch, Z. Kurzova 

(Prague, CZ) 

P953 Identification of Lyme disease spirochetes in 

humans and animals 

D. Hulínská, J. Voty‘pka, H. Drevová, K. Langrova, 

M. Bojar, M. Valesˇová (Prague, CZ) 

P954 Diversity of Borrelia burgdorferi sensu lato in 

the Russian Far East 

O. Mediannikov, L. Ivanov, N. Zdanovskaya, 

R. Vorobyova, P.-E. Fournier, I. Tarasevich, D. Raoult 

(Moscow, Khabarovsk, RUS; Marseille, F) 

P955 A new recombinant IgG and IgM line 

immunoblot improves serodiagnosis of early 

Lyme borreliosis 

G. Goettner, U. Schulte-Spechtel, V. Fingerle, 

G. Liegl, B. Wilske (Munich, D) 

P956 The first study of identification of Borrelia, 

Ehrlichia and Babesia in Ixodes ricinus ticks 

from Lithuania using molecular methods 

D. Ambrasiene, I. Vascilo, A. Jenkins, 

A.-G. Allum, L. Strand, B.-E. Kristiansen 

(Kaunas, Vilnius, LIT; Bo i Telemark, Skien, N) 

12:00–13:00 

Molecular bacteriology: characterisation of 

agents 

P957 Improved automated ribotyping using HindIII 

to discriminate previously uniform Listeria 

monocytogenes serotype 4b strains 

I. Heller, K. Grif, M. Dierich, R. Würzner 

(Innsbruck, A) 

P958 Detection of BFT, the isoforms of the 

enterotoxin gene and cfiA gene in Bacteroides 

fragilis isolates of different origins 

G. Terhes, J. Soki, K. Ago, E. Urban, E. Nagy 

(Szeged, HUN) 

P959 Prevalence and characterisation of binary 

toxin (actin specific ADP-ribosyltransferase) 

from Clostridium difficile 

D. Decré, F. Barbut, C. Goncalves, B. Burghoffer, 

J.-C. Petit (Paris, F) 

P960 Molecular characterisation and prevalence of 

Clostridium difficile in Singapore 

W.Y. Leong, R. Das Ramadas, T.H. Koh, K.P. Song 



P961 Characterisation of Clostridium difficile 

strains isolated in different time periods and 

belonging to different ribotypes 

P. Spigaglia, V. Carucci, P. Mastrantonio (Rome, I) 

P962 Virulence in enterococci: chromosomal versus 

plasmidic location of virulence genes 

T.M. Leitão Semedo, M.F. Silva Lopes, 

J.J. Figueiredo Marques, M.T. Barreto Crespo, 

R. Tenreiro (Lisbon, P) 

P963 Identification of salmonella serotypes in 

sheep by PCR 

T. Zahraei-Salehi (Tehran, IR) 

P964 Molecular typing of Salmonella enterica 

serotype Typhimurium strains from Slovak 

Republic 

H. Drahovská, E. Mikasová, E. Kaclíková, 

R. Karpísˇková, M. Sásik, J. Turna 

(Bratislava, SK; Brno, CZ) 

P965 Detection of fimbrial adhesin genes in 

ESBL-producing Klebsiella strains isolated 

from nosocomial infections 

K. Matusiewicz, B. Maczynska, D. Olejniczak, 

A. Przondo-Mordarska, R. Franiczek 

(Wroclaw, PL) 

P966 Development and validation of Amplified 

Fragment Length Polymorphism (AFLP) 

for molecular epidemiology and identification 

of Klebsiella pneumoniae and Klebsiella 

oxytoca phylogenetic groups 

D. Jonas, B. Spitzmüller, F.D. Daschner, 

J. Verhoef, S. Brisse 

(Freiburg, D; Utrecht, NL; Paris, F) 

P967 Molecular serotyping of Klebsiella by 

restriction of the amplified capsular antigen 

gene cluster 

S. Brisse, S. Issenhuth-Jeanjean, P.A.D. Grimont 

(Paris, F) 

P968 Cloning of 16S rRNA genes amplified from 

normal and disturbed vaginal microflora 

points to a strong assocation between 

Atopobium vaginae, Gardnerella vaginalis 

and bacterial vaginosis 

R. Verhelst, H. Verstraelen, G. Claeys, 

G. Verschraegen, J. Delanghe, L. Van Simaey, 

C. De Ganck, M. Temmerman, M. Vaneechoutte 

(Ghent, B) 

P969 Molecular typing of Vibrio cholerae strains 

having different sets of “pathogenicity 

islands” 

E.A. Kostromitina, G.A. Yeroshenko, 

N.I. Smirnova (Saratov, RUS)


P970 Comparative study of enterotoxigenic 

Bacteroides fragilis strains isolated in France 

and in Poland 

P. Obuch-Woszczatynski, A. van Belkum, 

L. Dubreuil, D. Dzierzanowska, H. Pituch, 

M. Luczak, F. Meisel-Mikolajczyk (Warsaw, PL; 

Rotterdam, NL; Lille, F) 

P971 Rapid detection of mutations in Candida 

albicans by pyrosequencing technique 

G. Orrù, D. Concas, V. Piras, S. Cosentino, 

M.B. Pisano, M.E. Fadda (Cagliari, Monserrato, I) 

P972 Development of a novel typing method for 

the Escherichia coli verocytotoxin 2 variants. 

Correlations to the clinical manifestations 

S. Persson, F. Scheutz, K.E.P. Olsen 


P973 Application of molecular biological techniques 

to the study of alterations in hamster 

gut microflora and assessment of treatment 

with Saccharomyces boulardii 

L. Coroler, G. Philippe-Taine, E. Bayart, T. Cécile, 

J.-M. Gillardin, H. Goïot (Compiègne, F) 

P974 Identification of Acinetobacter calcoaceticus- 

A. baumannii complex by sequence analysis 

of the 16S-23S rDNA spacer region 

Y.F. Wei, H.C. Chang, M. Vaneechoutte, 

A.H. Huang, T.C. Chang (Tainan, TW; Ghent, B) 

P975 Utility of the CVD432 probe for identification 

of enteroaggregative Escherichia coli 

amongst isolates from traveller’s diarrhoea 

L.R. Macfarlane, J.N. Fletcher, R. Ashton, 

P.A. Chapman, A.M. Snelling, I.N. Okeke 

(Bradford, Sheffield, UK; Pennsylvania, USA) 

P976 Shiga toxin-producing Escherichia coli O157 

in Slovenia 

P. Zabukovnik, A. Andlovic, A. Zore (Ljubljana, SI) 

12:00–13:00 

Urinary tract infections 

P977 Prevalence and aetiology of chronic bacterial 

prostatitis 

M. Sukhorukova, B. Gvasalia, I. Tascherev, 


P978 Comparison of prevalence and clinical 

management of prostatitis in the Italian 

and North American experience 

F. Marchetti, M. Rizzo, F. Travaglini, A. Trinchieri, 

C. Nickel (Verona, Florence, Milan, I; Kingston, CAN) 

P979 Aetiology and resistance of community 

urinary tract infections in São Paulo, Brazil: 

a three-year survey with 27,437 positive 

cultures 

C. Kiffer, C. Oplustil, J. Sampaio, L. Kudo, 

C. Mendes (Sao Paulo, BR) 

P980 Resistance of E. coli isolates from pregnant 

and non-pregnant women with communityacquired 

urinary tract infections in Russia: 

results of multicentre studies UTIAP-2002 and 

ARIMB 

V. Rafalski, A. Shevelev, L. Stratchounski 


P981 Community-acquired urinary tract infections. 

A large scale prospective study of medical 

practices in French emergency departments 

D. Elkharrat, F. Benhamou, P. Briquet-Brochard, 

C. Ginzburg, C. Leroux 

for the APPUI Study Group 

P982 Prostatitis syndromes and Stamey-Meares 

test results. Recording of 6-year experience in 

the department of internal medicine of a 

Greek tertiary hospital 

P. Panagopoulos, I. Katsarolis, G. Koratzanis, 

K. Kanellakopoulou, H. Giamarellou (Athens, GR) 

P983 Simultaneous urinary and respiratory 

infection or respiratory manifestations of 

urinary infection? 

J. Losa, M. Tejero, L. Moreno, M. Velasco, 

R. Barba, A. Espinosa, C. Guijarro, A. Delgado- 

Iribarren, J. Valverde, V. Castilla, A. Zapatero 

(Madrid, E) 

P984 Risk factors for bacteriuria due to 

Pseudomonas or Enterococcus in patients 

hospitalised through the emergency 

department 

D. Raveh, I. Rosenzweig, B. Rudensky, 

A.M. Yinnon (Jerusalem, IL) 

P985 Influence of Escherichia coli virulence factors 

in the levels of C reactive protein in febrile 

urinary tract infections 

A. Smithson, J. Ruiz, S. Soto, J.P. Horcajada, 

J.A. Martinez, A. Moreno-Martinez, J. Vila, 

J. Mensa (Barcelona, E) 


page 95


12:00–13:00 

Mycology: candida and aspergillosis 

P986 Initiation of an active surveillance programme 

on yeast-related bloodstream infections in 

France (ASPYRIF) 

E. Dannaoui on behalf of the French Mycoses 

Study Group 

P987 Nosocomial candidaemia: emerging resistance, 

newer antifungals and cost implications 

A. Guleri, G.D. Corcoran, S.R. Alcock, 

A.B.J. Speekenbrink, G.S. Shankland 

(Glasgow, UK) 

P988 Candidaemia: epidemiological data, 

complications and outcome of patients from 

the VAMC during seven years of evaluation 

G. Gonzalez-Claudio, M. Colon, E. Arroyo, 

C. Rivera-Vazquez, S. Saavedra, C. Ramirez-Ronda 

(San Juan, PR) 

P989 The risk-factors of candidaemia in cancer 

patients after surgical operation and patients 

receiving chemotherapy 

M. Koziol-Montewka, A. Miroslaw, 

K. Buczkowski, A. Chudnicka, A. Magrys, 

A. Kolodziejek, B. Gabczynska, E. Staroslawska, 

M. Montewka, M. Wojtowicz (Lublin, PL) 

P990 Evaluation of BacT/ALERT 3D system to 

diagnose bloodstream infections due to 

yeasts 

M.A. Miguel, M. Cuervo, M. Lecuona, B. Castro, 

M.J. Ramos, M.I. Montesinos, A. Sierra 

(Sta Cruz de Tenerife, E) 

P991 Candida spp. in a large Italian paediatric 

hospital: species distribution and comparison 

of the susceptibilities to fluconazole and 

voriconazole 

G. Manno, A. Scaramuccia, L. Pescetto, C. Peri, 

M. Mentasti, R. Bandettini (Genoa, I) 

P992 Effect of voriconazole on ergosterol content 

of C. krusei 

S. Costa-de-Oliveira, C. Pina-Vaz, E. Pinto, 

A. Oliveira, C. Tavares, A. Gonçalves Rodrigues 

(Porto, P) 

P993 Trends in species distribution and antifungal 

susceptibility in Candida wound infections: 

an overview of a 6-year period 

J. Martínez-Alarcón, T. Peláez, J.V. Guinea, 

O. Cuevas, P. Muñoz, M. Rodríguez-Créixems, 


P994 UK enhanced surveillance of invasive fungal 

infections in very low birth weight infants 

T. Lamagni, L. Clerihew, W. McGuire 

(London, Dundee, UK) 


P995 Surveillance cultures of throat and rectum 

combined with enteral polyenes control 

fungal infections in prolonged paediatric 

illness 

S. Rajan, N. Taylor, P.B. Baines, H.K.F. van Saene 

(Liverpool, UK) 

P996 Candida dubliniensis in Kuwait 

Zi. Khan, S. Ahmad, E. Mokaddas, N. Al-Sweih, 

R. Chandy (Kuwait, KWT) 

P997 Candida glabrata fungaemia: an uncommon 

entity affecting the elderly 

M. Sánchez-Somolinos, P. Muñoz, L. Alcalá, 

T. Peláez, M. Rodríguez, J. Guinea, E. Bouza 

(Madrid, E) 

P998 Candida spp. in patients with otitis externa 

I. Radonjic, A. Dzamic, L. Petkovic, A. Trpkovic, 

N. Arsovic, V. Arsic Arsenijevic (Belgrade, CS) 

P999 Recurrent vulvovaginal candidiasis: 

prevalence, antifungal susceptibility patterns 

and genotyping of different species 

S. Asticcioli, R. Migliavacca, E. Nucleo, M. Spalla, 

L. Sacco, L. Pagani (Pavia, I) 

P1000 Invasive aspergillosis: an emerging pathogen 

with a huge mortality in non-haematooncological 

patients 

W. Meersseman, S.J. Vandecasteele, 

E. Van Wijngaerden, J. Maertens, A. Wilmer, 

W.E. Peetermans (Leuven, B) 

P1001 Epidemiology of invasive aspergillosis in a 

teaching hospital, France: 

a 6-year survey (1998–2003) 

A. Cornillet, C. Camus, S. Nimubona, V. Gandemer, 

P. Tattevin, C. Belleguic, S. Chevrier, C. Meunier, 

C. Lebert, M. Aupée, B. Lelong, C. Guiguen, 

J.-P. Gangneux for the Aspergillosis Study Group 

P1002 Invasive aspergillosis in patients with COPD 

G. Serrate, B. Font, D. Mariscal, M. Sala, 

E. Antón, F. Segura (Sabadell, E) 

P1003 Evaluation of serum galactomannan ELISA 

during caspofungin therapy: results from the 

Caspofungin Salvage Invasive Aspergillosis 

Study 

J. Maertens, A. Glasmacher, D. Selleslag, 

M. Layton, A. Taylor, C. Sable, N. Kartsonis 

(Leuven, B; Bonn, D; Brugge, B; West Point, USA) 

P1004 Screening for Aspergillus galactomannan 

antigenemia in a haematology unit: 

how useful is it in daily practice ? 

A. Sonet, Y. DeGheldre, B. Delaere, C. Doyen, 

A. Bosly, Y. Glupczynski (Yvoir, B)


P1005 Diagnosing of invasive aspergillosis during 

antifungal therapy by polymerase chain 

reaction on blood samples 

C. Lass-Flörl, A. Petzer, M. Dierich (Innsbruck, A) 

P1006 Air surveillance of Aspergillus: 

are two different growth media required? 

J. Guinea, T. Peláez, J. Blanco, O. Cuevas, 

J. Martínez-Alarcón, L. Alcalá, P. Muñoz, E. Bouza 

(Madrid, E) 

P1007 In vivo interaction between caspofungin and 

flucytosine in a murine model of disseminated 

aspergillosis 

E. Dannaoui, O. Lortholary, F. Dromer (Paris, F) 

P1008 Activation of the complement system in 

cerebral aspergillosis 

G. Rambach, I. Mohsenipour, H. Maier, J. Rainer, 

G. Vago, M. Dierich, C. Speth 

(Innsbruck, A; Milan, I) 

P1009 Genotypic characterisation of Aspergillus spp. 

isolates from patients with cystic fibrosis by 

Random Amplified Polymorphic DNA PCR 

M. Serrano, A. Perkins, T. Alarcón, B. Buendía, 

D. Monclús, M. López-Brea (Madrid, E) 

12:00–13:00 

Molecular bacteriology: Staphylococcus 

P1010 Molecular epidemiology of bacteraemia due 

to methicillin-resistant and methicillinsusceptible 

Staphylococcus aureus in a 

tertiary hospital in Madrid 

J. Garcia-Martinez, S. De Miguel, F. Sanz, 

F. Chaves, J. Otero (Madrid, E) 

P1011 Real-time PCR for Staphylococcus aureus: 

identification at species level and detection 

of mecA gene 

T. Alarcón, J.A. García-Campos, M.S. Abanades, 

D. Monclus, D. Domingo, M. Lopez-Brea 

(Madrid, E) 

P1012 A comparative genomic hybridization study 

of epidemic strains of methicillin-resistant 

Staphylococcus aureus in Canada 

S. Christianson, M.R. Mulvey (Winnipeg, CAN) 

P1013 Recent trends in molecular epidemiology of 


in Finland 

A.-M. Santala, O. Lyytikäinen, M. Kardén-Lilja, 

S. Ibrahem, S. Salmenlinna, A. Virolainen- 

Julkunen, J. Vuopio-Varkila (Helsinki, FIN) 

P1014 Existence of PVL-genes and SCCmec IV 

amongst Finnish CA-MRSA strains 

M. Kardén-Lilja, J. Vuopio-Varkila, S. Ibrahem, 

S. Salmenlinna, O. Lyytikäinen, A. Virolainen- 

Julkunen (Helsinki, FIN) 

P1015 Evaluation of susceptibility methods for 

detection of methicillin resistance in 


M. Kantzanou, E. Alepopoulou, M. Panopoulou, 

E. Kantzanos, A. Grapsa, I. Dimopoulou, S. Kartali 

(Alexandroupolis, GR) 

P1016 Amplification of DNA fragments surrounding 

rare restriction sites ( ADSRRS-fingerprinting) 

for typing Staphylococcus aureus isolated 

from patients with recurrent furunculosis 

W. Baranska-Rybak, R. Nowicki, E. Scieburako, 

J. Kur, E. Arlukowicz, A. Samet (Gdansk, PL) 

P1017 Comparison of well-established with new 

genotyping methods for typing Staphylococcus 

aureus 

N. Malachowa, A. Sabat, K. Kosowska, 

J. Krzyszton-Russjan, J. Empel, J. Miedzobrodzki, 

P.C. Appelbaum, W. Hryniewicz 

(Cracow, Warsaw, PL; Hershey, USA) 

P1018 Coagulase-negative staphylococci strain 

types affect visual outcome in patients with 

endophthalmitis 

S. Lightman, A. Khan, N. Okhravi, W. Lynn, 

T. Elliott, P. Lambert, A. Worthington (London, UK) 

P1019 Evaluation of Roche LightCycler kits for the 

detection of methicillin-resistant Staphylococcus 

aureus in patient screening broths 

K. Levi, K.J. Towner (Nottingham, UK) 

P1020 Sigma B dependent expression of oxacillin 

resistance in Staphylococcus epidermidis: 

transcriptional analysis of mecA, and other 

factors required for resistance expression 

J.K.-M. Knobloch, J. Huck, S. Jäger, 

M.A. Horstkotte, D. Mack (Hamburg, D) 

P1021 Detecting the response of Staphylococcus 

aureus to antimicrobial agents by measuring 

changes in mRNA levels using a flow through 

microarray 

R.M. Anthony, A.R.J. Schuitema, L. Oskam, 

P.R. Klatser (Amsterdam, NL) 


page 97


12:00–13:00 

Progress in pharmacokinetics and 

pharmacodynamics – I 

P1022 Pharmacokinetics of telithromycin in 

plasma and soft tissue after single-dose 

administration in healthy volunteers 

R. Gattringer, F. Traunmueller, E. Urbauer, 

M. Zeitlinger, M. Mueller, C. Joukhadar 

(Vienna, A) 

P1023 Pharmacokinetics of tigecycline in healthy 

adult volunteers and in subjects with renal 

impairment 

A. Meagher, B. Cirincione, M. Piedmonte, S. Troy, 

P.G. Ambrose (Buffalo, Phildelphia, USA) 

P1024 Comparative pharmacodynamics of ABT492 

and ciprofloxacin (CIP) with Escherichia coli 

and Pseudomonas aeruginosa in an in vitro 

dynamic model 

I. Lubenko, A. Firsov, S. Vostrov, I. Alferova, 

Y. Portnoy, S. Zinner 

(Moscow, RUS; Cambridge, USA) 

P1025 ABT492 versus levofloxacin in an in vitro 

dynamic model: comparative pharmaco - 

dynamics with differentially susceptible 

Staphylococcus aureus and the relative ability 

to prevent the selection of resistant mutants 

A. Firsov, I. Lubenko, S. Vostrov, Y. Portnoy, 

S. Zinner (Moscow, RUS; Cambridge, USA) 

P1026 Pharmacodynamic activity of iclaprim vs 

resistant Streptococcus pneumoniae using 

an in vitro model 

G.G. Zhanel, M. Goolia, J. Rusen, N.M. Laing, 

A.M. Noreddin, K. Nichol, S. Hawser, K. Islam, 

D.J. Hoban (Winnipeg, CAN; Munchenstein, CH) 

P1027 Single dose pharmacokinetics of telavancin in 

healthy elderly subjects 

K. Duchin, J. Shaw, E. Spencer, J. Seroogy, 

S. Barriere, D. Wilbraham 

(South San Francisco, USA; London, UK) 

P1028 Single dose pharmacokinetics of telavancin 

in subjects with renal dysfunction 

K. Duchin, J. Shaw, E. Spencer, J. Seroogy, 

S. Barriere, D. Wilbraham 

(South San Francisco, USA; London, UK) 

P1029 Efficacy of telavancin (TD-6424), a rapidly 

bactericidal agent with multiple mechanisms 

of action, in a murine model of MRSA 

pneumonia 

S. Hegde, N. Reyes, R. Skinner, K. Kaniga 

(South San Francisco, USA) 


P1030 Influence of gender on the pharmacokinetics 

of BAL9141 after intravenous infusion of 

Pro-drug BAL5788 

A.H. Schmitt-Hoffmann, B. Roos, M. Heep, 

M. Schleimer, E. Weidekamm, A. Man, N. Abdou 

(Basle, CH; Lenexa, USA) 

P1031 BAL5788 in patients with complicated skin 

and skin structure infections caused by Grampositive 

pathogens including methicillinresistant 

Staphylococcus species. Interim 

pharmacokinetic results from 20 patients 

A.H. Schmitt-Hoffmann, M. Harsch, M. Heep, 

M. Schleimer, T. Brown, A. Man, W. O'Riordan 

(Basle, CH; Chula Vista, USA) 

P1032 Dose adjustment in subjects with normal 

and impaired renal function based on the 

pharmacokinetics of BAL5788 

A.H. Schmitt-Hoffmann, B. Roos, M. Schleimer, 

E. Weidekamm, T. Brown, M. Heep, A. Man, 

L.G. Nilsson (Basle, CH; Uppsala, S) 

P1033 Pharmacokinetics of BAL4815, a new azole 

antifungal, after administration of single 

ascending intravenous doses of its pro-drug 

BAL8557 

A.H. Schmitt-Hoffmann, B. Roos, M. Heep, 

M. Schleimer, E. Weidekamm, A. Man, 

M. Roehrle (Basle, CH; Neu-Ulm, D) 

P1034 Anidulafungin (ANID) pharmacokinetics are not 

affected by concomitant voriconazole (VORI) 

J. Dowell, J. Schranz, J. Wilson, A. Baruch, 

G. Foster (King of Prussia, New York, USA) 

P1035 Population pharmacokinetics confirms 

absence of anidulafungin drug-drug 

interactions 

M. Stogniew, J. Dowell, D. Krause, T.J. Henkel 

(King of Prussia, USA) 

P1036 Assessment of the pharmacokinetics of 

anidulafungin in patients with invasive 

aspergillosis receiving concomitant liposomal 

amphotericin 

J. Dowell, J. Schranz, M. Stogniew, D. Krause, 

T.J. Henkel (King of Prussia, USA) 

P1037 Rifampicin and ritonavir do not affect the 

pharmacokinetics of micafungin (FK463), 

an echinocandin antifungal 

N.A. Undre, P. Stevenson, D.D. Amakye 

(Munich, D; Leeds, UK) 

P1038 Pharmacokinetics of itraconazole and 

OH-itraconazole as a nanocrystal formulation 

in healthy volunteers after single and multiple 

doses 

J.W. Mouton, J.P. Donnelly, R. Crabbe 

(Nijmegen, NL; Beerse, B)


P1039 Pharmacokinetics and tissue penetration 

of linezolid in patients with diabetic foot 

infection 

G. Haase, M. Sass, J. Majcher-Peszynska, 

S.C. Müller, R.G. Mundkowski, W. Schareck, 

B. Drewelow (Rostock, D) 

P1040 Evaluation of tigecycline, linezolid, 

quinupristin-dalfopristin, arbekacin and 

daptomycin alone and in combination with 

various antimicrobials against two clinical 

strains of vancomycin-resistant Staphylococcus 

aureus in an in vitro pharmacodynamic model 

V. Huang, W. Brown, M. Rybak (Detroit, USA) 

P1041 Evaluation of cefepime, arbekacin, 

daptomycin, gentamicin, tobramycin, and 

tigecycline alone and in combination against 

methicillin-resistant Staphylococcus aureus in 

an in vitro pharmacodynamic infection model 

V. Huang, M. Rybak (Detroit, USA) 

P1042 Simultaneous methicillin-resistant Staphylococcus 

aureus & vancomycin-resistant 

Enterococcus faecalis infections in an in vitro 

pharmacodynamic model: a comparison 

of daptomycin, arbekacin, linezolid and 

tigecycline activities 

K. Tedesco, M. Rybak (Detroit, USA) 

P1043 Pharmacodynamics of amoxicillin/clavulanic 

acid against Haemophilus influenzae in an in 

vitro kinetic model: a comparison of different 

dosage regimens including a pharmacokinetically 

enhanced formulation 

E. Löwdin, O. Cars, I. Odenholt (Uppsala, S) 

P1044 The comparative antibacterial effect of 

ertapenem and ceftriaxone on E. coli studied 

in an in vitro pharmacokinetic model of 

infection 

K. Bowker, A. Noel, A. MacGowan (Bristol, UK) 

P1045 Comparison of ertapenem, ampicillin, and 

meropenem against the intracellular forms of 

Listeria monocytogenes in human THP-1 

macrophages 

S. Lemaire, S. Van de Velde, S. Carryn, F. Van 

Bambeke, M.P. Mingeot-Leclercq, P. Tulkens 

(Brussels, B) 

P1046 Pharmacokinetic-pharmacodynamic modeling 

of activities of cefpodoxime and cefixime 

based on in vivo tissue concentrations and in 

vitro kill curves 

H. Derendorf, P. Liu, K. Rand, B. Obermann 

(Gainesville, USA; Munich, D) 

P1047 Single-dose pharmacokinetics of cefodizime 

in acutely ill elderly patients 

B. Meyer, F. Traunmueller, T. Staudinger, 

G. Locker, R. Schmid, F. Thalhammer (Vienna, A) 

P1048 Comparative effects of ertapenem and 

ceftriaxone on the normal intestinal 

microflora 

M.W.R. Pletz, M. Rau, A. de Roux, O. Burkhardt, 

M. Kurowski, H. Lode, C.E. Nord 

(Berlin, D; Stockholm, S) 

P1049 Multiple dose and steady-state pharmacokinetics 

of ertapenem compared to ceftriaxone 

in healthy young male and female volunteers 

M. Rau, M.W.R. Pletz, J. Bulitta, A. de Roux, 

G. Schreiber, C.E. Nord, M. Kurowski, G. Kruse, 

H. Lode (Berlin, Nuremburg, D; Stockholm, S) 

12:00–13:00 

Pathogenesis 

P1050 Bacterial inhibition of phosphatidylcholine 

synthesis induces apoptosis in brain cells 

J. Zweigner, S. Jackowski, S. Smith, 

M. van der Merwe, J. Weber, E. Tuomanen 

(Berlin, D; Memphis, USA) 

P1051 Bacterial cell-wall derived products induce 

a pro-inflammatory and pro-fibrogenetic 

phenotype in murine hepatic stellate cells 

P. Brun, D. Martines, M. Pinzani, G. Palù, 

I. Castagliuolo (Padua, I) 

P1052 Lipopolysaccharide-induced vascular 

endothelial growth factor expression 

A.J. Huh, Y.A. Kim, Y.W. Kim, J.S. Yeom, 

Y.G. Song, K.H. Chang, J.M. Kim 

(Go-yang, Seoul, KOR) 

P1053 Antistaphylococcal effect of recombinant 

human erythropoietin 

H. Baskin, Y. Baskin, Y. Dogan, I.H. Bahar 

(Izmir, TR) 

P1054 Ex vivo release of pro-inflammatory cytokines 

of blood monocytes of patients with sepsis: 

correlation to the initiation of symptoms and 

to monocyte apoptosis 

M. Kyriakopoulou, M. Raftogiannis, F. Baziaka, 

I. Skiadas, H. Giamarellou, E.J. Giamarellos- 


P1055 Adherence factors of ocular isolates of 

nontypeable Haemophilus influenzae from 

Saudi Arabia 

A. Adlan, J.N. Fletcher, A.A. Al-Rajhi, A. Al-Theeb, 

A.M. Snelling (Riyadh, SA; Bradford, UK) 

P1056 Genetic relationships among nontypable 

Haemophilus influenzae isolates presenting 

different adhesins profiles 

B. Rybak, E. Augustynowicz, A. Gzyl, G. Gniadek, 

J. Slusarczyk, A. Samet (Gdansk, Warsaw, PL) 


page 99


P1057 Bac protein based recombinant peptides as 

possible means for vaccine development 

against GBS infection 

L. Meringova, I. Ustinovitch, K. Grabovskaya, 

G. Leontieva, A. Suvorov (St.Petersburg, RUS) 

P1060 Bacterial adherence ability and adherence 

factors of quinolone sensitive and resistant 

E. coli strains isolated from cirrhotic patients 

I. Gascón, P. Más, R. Francés, S. Pascual, 

V. Merino, J. Such, J. Plazas 

(Alicante, Valencia, E) 

P1061 Effect of quinolones on the induction of the 

loss of pathogenicity islands in uropathogenic 

Escherichia coli 

S.M. Soto, J.P. Horcajada, J. Mensa, 

M.T. Jiménez de Anta, J. Vila (Barcelona, E) 

P1062 Use of deletion mutations to explore 

structure-function relationships in 

Clostridium tetani neurotoxin 

I. Belyi (Moscow, RUS) 

P1063 The contribution of a subspecies-specific type 

IV secretion system to pathogenicity in 

Campylobacter fetus venerealis 

G. Gorkiewicz, C. Schober, S. Scheicher, 

S. Kienesberger, R. Zechner, E. Zechner (Graz, A) 

P1064 The role of the SabA adhesin and other 

Helicobacter pylori virulence factors in 

activation of human neutrophils 

M. Unemo, D. Ilver, D. Danielsson, M. Hurtig, 

T. Borén, S. Teneberg (Örebro, S) 

P1065 Characterisation of the penetration ability and 

cytotoxicity of Serratia marcescens 

L.-H. Su, C.-H. Chiu, C. Chu, T.-L. Wu, J.T. Ou, 

T.V. Riley, B.J. Chang (Taoyuan, TW; Perth, AUS) 

P1066 Modulation of Listeria monocytogenes 

interaction with cellular substrate by 

ß-lactam antibiotics and human serum 

transferrin 

G. Mihaescu, B. Manolescu, L. Petrache 

(Bucharest, RO) 

P1067 Treponema pallidum pallidum (strain Nichols), 

but not Treponema phagedenis (biotype 

Reiter), has an apical structure that may be a 

pathogenic factor 

A. Magalhães-Sant'Ana, C. Nogueira, G. Marrão, 

G. Rocha (Coimbra, P) 

P1068 Route of natural exposure in animal model of 

brucellosis 

Z. Yumuk, S. Caliskan, D. Dundar, V. Dundar 

(Kocaeli, TR) 


12:00–13:00 

Insights into hepatitis 

P1069 Efficacy of lamivudine in treatment of precore 

mutant chronic hepatitis B 

M.R. Hasanjani Roushan, M.A. Shafai, 

S.A. Asgharzadeh Ahmadi (Babol, IR) 

P1070 Molecular epidemiology of hepatitis B in 

Denmark 

N. Fisker, C. Pedersen, M. Lange, N.T.T. Nguyen, 

K.T.T. Nguyen, J. Georgsen, P.B. Christensen 

(Odense, DK) 

P1071 Much gained by integrating contact tracing 

and vaccination in the hepatitis B antenatal 

screening programme in Amsterdam, 

1992–1999 

J.E. van Steenbergen, D. Baayen, 

P.G.H. Peerbooms, R.A. Coutinho, 

J.A.R. van den Hoek 

(Utrecht, Amsterdam, Netherlands, NL) 

P1072 Different B2-microglobulin (b2m) curves in 

chronic hepatitis B (CHB) patients, under 

long-term lamivudine (LAM) monotherapy or 

interferon plus lamivudine (IFN/LAM) 

combination treatment. Relationship with 

virological breakthrough (VB) 

I.S. Elefsiniotis, K.D. Pantazis, I. Glynou, 

N.V. Fotos, C. Mavrogiannis, H. Kada 

(Athens, GR) 

P1073 Psychiatric adverse effects of interferon alpha 

2a treatment in chronic hepatitis patients 

N. Kaya, E. Turk Aribas, A.C. Inkaya, M. Bitirgen 

(Konya, TR) 

P1074 The prevalence of hepatitis B virus precore 

mutant in patients with chronic hepatitis B 

virus infection 

F. Yarkin, Z. Altun, O. Bayramoglu, N. Saltoglu, 

F. Koksal (Adana, TR) 

P1075 Antigenic property of different sequence 

variants of the hepatitis B surface antigen 

wild types and vaccine escape mutants 

T. Ulanova, J. Yokosawa, A. Burkov, V. Puzyrev, 

A. Obriadina 

(Nizhniy Novgorod, RUS; Atlanta, USA) 

P1076 Performance of hepatitis B surface antigen 

(HBsAg) assays for the detection of 

recombinant and native HBsAg mutants and 

screening for HBsAg mutants in isolated anti- 

HBc positive sera 

B. Weber, N. Van Der Taelem-Brulé 

(Junglinster, LUX)


P1077 Hepatitis B virus genotypes in the Czech 

Republic 

O. Strunecky‘, V. Nemecek (Prague, CZ) 

P1078 High prevalence of HFE gene mutations in 

patients with hepatitis B and other liver 

diseases in the Czech Republic 

I. Putova, M. Cimburova, B. Cieslarova, 

J. Stransky, J. Horak (Prague, CZ) 

P1079 Performance of AxSYM HBsAg in a Danish 

patient population 

I. Sleimann Petersen, A. Svendsen, G. Momsen, 

P. McNair, H. Westh (Hvidovre, DK) 

P1080 Cytomegalovirus acute viral hepatitis – 

results of a six-year study (1998-2003) after 

introducing CDC case definitions and 

hepatitis B vaccination 

A. Radulescu, D. Tatulescu, V. Zanc, M. Turdean 

(Cluj-Napca, RO) 

P1081 Results of vaccination against VHB and VHA 

in HIV-positive patients 

V. Aster, M. Stankova, H. Rozsypal (Prague, CZ) 

P1082 Evaluation of the Artus HBV LightCycler kit 

for quantitative detection of hepatitis B virus 

in serum samples 

K. Levi (Nottingham, UK) 

P1083 Correlation of circulating endothelin-1 and 

nitrates/nitrites with the liver histopathological 

staging and grading in patients with chronic 

viral hepatitis B 

Y. Ersoy, N.M. Bayraktar, S. Gunal, B. Mizrak, 

G. Bilisik, I.H. Ozerol (Malatya, TR) 

P1084 Hepatitis D super infection that developed 

due to endoscopy 

F. Yildiz Zeyrek, H. Ozbilge, O. Sirmatel, 

F. Sirmatel (Sanliurfa, TR) 

P1085 The epidemiology and phylogeny of TT virus 


M. Salakova, V. Nemecek, J. König, R. Tachezy 

(Prague, CZ) 

P1086 Absence of occult HCV and HBV infections in 

haemodialysis patients 

M.L. Mateos, J. Chacón, P. Ruiz, G. Tabernero, 

M. Fernandez-Lucas, J.L. Teruel (Madrid, E) 

12:00–13:00 

Streptococci: resistance and epidemiology 

P1087 Streptococcus pyogenes resistance to 

erythromycin and selection pressure of 

macrolides 

M. Kolar, K. Urbanek, L. Cekanova, D. Koukalova, 

P. Hejnar (Olomouc, CZ) 

P1088 Susceptibility of Streptococcus pyogenes to 

telithromycin and erythromycin: 

results from PROTEKT (Years 1-3) 

R. Reinert, D. Felmingham 


P1089 Antibiotic susceptibilities of invasive group 

A streptococci in England, Wales and 

Northern Ireland: a comparison of results 

between hospital laboratories and the 

national reference laboratories 

S. Neal, M. Warner, T. Lamagni, M. Emery, 

C. Dhami, T. Parsons, A. Efstratiou (London, UK) 

P1090 Macrolide resistance rates and resistance 

phenotypes of invasive Streptococcus pyogenes 

isolates in Greece 

A. Stathi, J. Papaparaskevas, P.T. Tassios, 

L. Zachariadou, N.J. Legakis, A. Pangalis 

The Hellenic Strep-EURO Study Group 

P1091 Large differences in resistance to erythromycin 

in Streptococcus pyogenes isolates of 

pharyngitis among regions in Spain 

E. Perez-Trallero, C. Garcia-Rey, E. Perea, 

D. Romero, L. Calbo, M. Casal, J. Garcia-de- 

Lomas, L. Aguilar – The Spanish Surveillance 

Group for Respiratory Pathogens 

P1092 Erythromycin-resistant Streptococcus 

pyogenes 

G. Lazarevic, S. Laban, M. Jovanovic, 

B. Potkonjak (Belgrade, CS) 

P1093 Phenotypic and genotypic characterisation of 

macrolide-resistant Streptococcus pyogenes 

strains isolated in the Czech Republic during 

two years (2001-2002) 

V. Jakubu, P. Urbaskova, L. Strakova, O. Melter 

(Prague, CZ) 

P1094 Increasing rate of tetracycline resistance in 

Streptococcus pyogenes in Sweden 

E. Bloom, J. Darenberg, F. Norrberg, 

B. Henriques-Normark, C. Schalen, A. Jasir – 

Strep-EURO 


page 101


P1095 Multicentre evaluation of macrolide and 

ketolide activities and different genotypes of 

erythromycin resistance in Italian streptococci 

A. Mazzariol, R. Koncan, G. Bahar, L. Ricci, 

P. Nicoletti, P. Pecile, F. Luzzaro, R. Fontana, 

G. Cornaglia (Verona, I; Ankara, TR; Reggio Emilia, 

Florence, Varese, I) 

P1096 Incidence of fluoroquinolone-resistant betahaemolytic 

streptococci in North America 

(NA) and Europe (EU): Report from the 

SENTRY Antimicrobial Surveillance Program, 

1997–2002 

D.J. Biedenbach, M. Toleman, T. Walsh, R. Jones 

(North Liberty, USA; Bristol, UK) 

P1097 In vitro activity of telithromycin against 

erythromycin-resistant and susceptible 

viridans group streptococci isolated from 

blood 

I. Rodríguez-Avial, C. Rodríguez-Avial, E. Culebras, 

J.J. Picazo (Madrid, E) 

P1098 Resistance rates of viridans group streptococci 

in children attending day-care centres 

G. Melica, H. Carsenti Dellamonica, B. Dunais, 

C. Pradier, P. Dellamonica (Nice, F) 

P1099 The eagle effect revisited. Penicillin resistance 

in group G beta haemolytic streptococcal 

infection 

A. Pillai, S. Thomas, C. Williams (Dumfries, UK) 

12:00–13:00 

Resistance in Pseudomonas and other 

Gram-negative bacilli 

P1100 Suitability of current routinely-generated data 

for surveillance of antimicrobial resistance of 

Escherichia coli and Pseudomonas aeruginosa 

in the UK and Ireland 

R. Reynolds, N. Potz – BSAC Working Party on 

Bacteraemia Resistance Surveillance 

P1101 Diversity among 2481 Escherichia coli from 

women with community-acquired lower 

urinary tract infections in 17 countries 

(ECOSENS project) 

M. Landgren, H. Odén, I. Kühn, A. Österlund, 

G. Kahlmeter (Växjö, Stockholm, S) 

P1102 Characterisation of clinical isolates of 

Enterobacteriaceae resistant to third 

generation cephalosporins from a university 

hospital in Bratislava, Slovakia 

M. Zarnayova-Skopkova, E. Siebor, H. Bujdáková, 

C. Neuwirth (Bratislava, SK; Dijon, F) 


P1103 Role of clonal occurrences of multi-drugresistance 

(MDR) in the MYSTIC Programme 

(USA; 1999–2003) 

R. Jones, G. Deshpande, P. Rhomberg, H. Sader, 

T. Fritsche (North Liberty, USA) 

P1104 Optimising pharmacodynamic target 

attainment using the MYSTIC antibiogram 

(OPTAMA) – Acinetobacter sp. and 

P. aeruginosa in Europe, 2002 

R. Masterton, J. Kuti, C. Nightingale, D. Nicolau 

(Crosshouse, UK; Hartford, USA) 

P1105 Optimising pharmacodynamic target 

attainment using the MYSTIC antibiogram 

(OPTAMA) – Escherichia coli and Klebsiella 

pneumoniae in Europe, 2002 

R. Masterton, J. Kuti, C. Nightingale, D. Nicolau 

(Crosshouse, UK; Hartford, USA) 

P1106 Sustained activity of the carbapenems 

against Gram-negative pathogens: 6-year 

data from the UK MYSTIC (Meropenem Yearly 

Susceptibility Test Information Collection) 

programme 

R. Masterton on behalf of the UK MYSTIC Group 

P1107 P. aeruginosa clonal dissemination in Brazilian 

intensive care units during 2002 

C. Mendes, S. Sinto, J. Sampaio, S. Leao, 

C. Oplustil, P. Turner, C. Kiffer 

MYSTIC Brazil Group 

P1108 Resistance of Pseudomonas aeruginosa: 

10-year experience in a Portuguese hospital 

C. Marcelo, A. Azevedo, M. Pessanha, 

E. Gonçalves, T. Cruz, H. Silva, I. Alves, P. Bruno, 

N. Rosa, J. Santos, F. Martins, J. Esperança-Pina 

(Lisbon, P) 

P1109 Convergent resistance development 

between two carbapenems for Pseudomonas 

aeruginosa 

F. Walsh, S. Bracher, P. Turner, S.G.B. Amyes 

(Edinburgh, Cheshire, UK) 

P1110 Lack of association between hypermutation 

and antibiotic resistance development in 

Pseudomonas aeruginosa from intensive care 

unit patients 

O. Gutiérrez, C. Juan, M.D. Maciá, J.L. Pérez, 

A. Oliver (Palma de Mallorca, E) 

P1111 Detection and susceptibility testing of 

hypermutable Pseudomonas aeruginosa 

strains with the E-test 

M.D. Maciá, N. Borrell, O. Gutiérrez, J.L. Pérez, 

A. Oliver (Palma de Mallorca, E)


P1112 Partial reduction of antimicrobial resistance of 

Pseudomonas aeruginosa following new 

antibiotic strategies in an intensive care unit 

in Italy 

B. Allegranzi, A. Azzini, A. Luzzani, F. Rapagna, 

F. Favari, E. Concia (Verona, I) 

P1113 Polyphasic approach to the characterisation 

of Pseudomonas aeruginosa isolates from a 

Portuguese central hospital 

A.P. Fonseca, P. Correia, A. Fonseca, R. Tenreiro, 

J.C. Sousa (Porto, Lisbon, P) 

P1114 Emergence of Pseudomonas aeruginosa (PA) 

resistance to imipenem vs meropenem 

S. Navon-Venezia, Y. Mekuzas, O. Hammer-Muntz, 

D. Schwartz, Y. Carmeli (Tel Aviv, IL) 

P1115 Risk factors for emergence of resistant 

Pseudomonas aeruginosa to beta-lactams 

in intensive care units 

B. Georges, M. Archambaud, E. Bonnet, 

S. Saivin, J. Conil, P. Cougot, T. Seguin, 

C. Virenque (Toulouse, F) 

P1116 Molecular genotyping of Pseudomonas aeruginosa 

clinical isolates resistant to quinolones: 

detection of mutations in the gyr genes 

S. Ferreira, S. Mendo (Aveiro, P) 

P1117 In vitro effects of silicone oil on the growth 

and adherence of Pseudomonas aeruginosa 

S. Kirdar, M. Ucar, S. Ozden, Y. Dogan, H. Baskin, 

S. Kaynak, I.H. Bahar (Izmir, TR) 

P1118 Susceptibilities of clinical Acinetobacter 

baumannii and Stenotrophomonas 

maltophilia isolates to 14 antimicrobial 

agents: results of the Antimicrobial 

Resistance Surveillance Study of the Paul 

Ehrlich Society for Chemotherapy, 2001 

M. Kresken, F. Allerberger, D. Hafner, H. Seifert 

on behalf of the Working Group Antimicrobial 

Resistance of the Paul Ehrlich Society for 

Chemotherapy 

P1119 Resistance rates of Pseudomonas aeruginosa 

isolates using The Surveillance Network 

(TSN) Database – Greece 

G. Totos, C. Kleisiari, T. Konstantinidis, 

V. Gizaris, D. Sofianou (Athens, Thessalonica, 

Alexandroupolis, GR) 

P1120 Integrons carried by Enterobacteria from 

avian cloacal swabs harbour the same 

cassette arrays as isolates from clinical 

human origin 

F. Gionechetti, F. Gombac, C. Monti-Bragadin, 

C. Lagatolla, E. Tonin, L. Dolzani (Trieste, I) 

P1121 Study of an imipenem-resistant Klebsiella 

pneumoniae cluster in a Greek hospital 

S. Kanavaki, S. Karabela, H. Moraitou, 

P. Giakouppi, G. Dimopoulos, M. Makarona, 

S. Avgeropoulou, A. Vatopoulos, A. Rasidakis 

(Athens, GR) 

P1122 Epidemiology of Enterobacter aerogenes in 

Belgium: preliminary results of a multicentre 

survey 

Y. De Gheldre, Y. Glupczynski, C. Berhin, M. Hallin, 

M. Struelens, R. Boreux, P. De Mol, B. Jans 

on behalf of GDEPIH-GOSPIZ 

P1123 Antibiotic susceptibility in invasive E. coli 

isolates, Belgium, 2002 

E. Hendrickx, D. Piérard (Brussels, B) 

P1124 Dynamics of ciprofloxacin-resistance for 

Gram-negative bacilli isolated in urinary 

paediatric infections 

R. Filip, E. Petraru, M. Cirlan, C. Dahorea, 

G. Coman (Iasi, RO) 

P1125 Antimicrobial resistance of Escherichia coli 

isolated in bacteraemia during 2002: 

results from the Ile de France Microbiologist 

Network 

Y. Péan, M. Bingen, A. Boisivon, F. Faibis, 

M.-C. Demachy, B. Ferré, B. Hacquard, 

F. Richardin, A. Scanvic - Ile de France 

Microbiologist Network 

P1126 Colonisation of long-term-care facilities 

residents with antimicrobial-resistant 

enterobacteriaceae (EB) in Greece 

K. Kanellakopoulou, V. Grammelis, A. Kapaskelis, 

D. Chalkiadaki, I. Galani, K. Orlandou, 

M.K. Lazanas, H. Giamarellou (Athens, GR) 

P1127 Comparative evaluation of uropathogenic 

E. coli resistance during a five-year period 

D. Gianneli, O. Zarkotou, P. Kanellopoulou, 

K. Tryfinopoulou, C. Nikolopoulou, G. Chrysos 

(Piraeus, GR) 

P1128 Prevalence and antibiotic resistance of 

the most important urinary pathogens 

responsible for non-complicated cystitis 

in women: the IceA 2 Study 

A. Speciale, G. Nicoletti, R. Musumeci, G. Fadda, 

S. Caponera, C. Archibusacci, A. Rossi, E.A. Debbia, 

A. Marchese, M. Tellarini, G.C. Schito 

(Catania, Rome, Terni, Genoa, Milan, I) 

P1129 The prevalence of antibiotic resistance of 

Escherichia coli and enterococci isolated from 

faeces of pigs in communal farming areas of 

Mafikeng district (R.S.A.) 

M.S. Moneoang, P.T. Mmolawa (Mmabatho, ZA) 


page 103


12:00–13:00 

S. pneumoniae: resistance and epidemiology 

P1130 Antimicrobial resistance with Streptococcus 

pneumoniae in 2003 – Results of the 

Multinational GRASP Surveillance Program 

K. Heilmann, S. Beekmann, S. Richter, 

J. Garcia-de Lovias, G. Doern 

(Iowa City, USA; Valencia, E) 

P1131 Detection of internationally spread multiresistant 

Streptococcus pneumoniae clones in 

Germany using Multi Locus sequence typing 

B. Henrichfreise, S. Bagel, M. Kresken, 

K. Sherwood, B. Wiedemann (Bonn, D) 

P1132 Trend in antimicrobial susceptibility of 

nasopharyngeal Streptococcus pneumoniae 

recovered from Italian children: 

a seven-years study 

R. Bandettini, L. Pescetto, C. Peri, A. Scaramuccia, 

M. Mentasti, G. Manno (Genoa, I) 

P1133 The International Circumpolar Surveillance 

System for population-based surveillance of 

invasive pneumococcal disease, 1999–2002 

M. Bruce, T. Cottle, J. Butler, D. Parks, S. Deeks, 

T. Tam, M. Lovgren, L. Jette, K. Kristinsson, 

G. Sigmundsdottir, K. Brinklov Jensen, O. Lovoll, 

P. Nuorti, E. Herva, T. Hennessy, A. Parkinson 

(Anchorage, USA; Ottawa, Edmonton, Quebec, 

CAN; Reykjavik, IS; Nuuk, GL; Oslo, N; Helsinki, 

Oulu, FIN) 

P1134 Trends in beta-lactam resistance in communityacquired 

lower respiratory tract infection in 

the UK and Ireland 

R. Reynolds, D. Felmingham – BSAC Working 

Party on Respiratory Resistance Surveillance 

P1135 Susceptibility of Streptococcus pneumoniae 

respiratory isolates from adults in Spain 

(2001–2002) 

M. Gobernado, C. Garcia-Rey, C. Garcia-de-la- 

Fuente, V. Ausina, J. Ruiz, F. Marco, 

J. Garcia-de-Lomas, L. Aguilar 

The Spanish Surveillance Group for Respiratory 

Pathogens 

P1136 Serotypes and antimicrobial resistance of 

Streptococcus pneumoniae: evolution 

(1989–2003) in Asturias, Spain 

A. Fleites, R. Trabazo, F. Pérez, L. Molinos, 

A. Moreno, M. Hidalgo, J. Rodríguez and The 

Spanish Pneumococcal Infection Study Network. 


P1137 Investigation of genetic relatedness among 

penicillin-nonsusceptible pneumococci 

isolated in Turkey 

M. Bicmen, Z. Gulay (Izmir, TR) 

P1138 Selection of single step parC mutations 

among levofloxacin susceptible 

S. pneumoniae in Canada 

R.J. Davidson, H. Musgrave, S. Campbell, 

C. Howley (Halifax, CAN) 

P1139 Evolution of macrolide resistance in 

Streptococcus pneumoniae in Italy 

M. Monaco, R. Camilli, F. D'Ambrosio, 

M. Del Grosso, A. Pantosti (Rome, I) 

P1140 Evolution of levofloxacin activity against 

Streptococcus pneumoniae in France 

(1999–2002) 

C.J. Soussy, H. Drugeon (Creteil, Nantes, F) 

P1141 Trends of ceftriaxone resistance in Canadian 

strains of Streptococcus pneumoniae 

K. Wong, K. Green, S. Pong-Porter, T. Mazzulli, 

K. Weiss, R.J. Davidson, D. Church, D.J. Hoban, 

P. Kibsey, M. Kuhn, B. Toye, Y. Rzayev, 

A. Plevneshi, J. Powis, J. Fuller, O. Vanderkooi, 

D.E. Low on behalf of the Canadian Bacterial 

Surveillance Network 

P1142 Isolation and resistance patterns of 

S. pneumoniae in a 6-year period (1997–2003) 

S. Kanavaki, S. Karabela, M. Makarona, 

H. Moraitou, S. Arbilia, S. Triantaphyllou, 

A. Pefanis (Athens, GR) 

P1143 Macrolide and quinolone resistance 

mechanisms in Streptococcus pneumoniae 

population from children in day-care centers 

and orphanages in Asian Russia 

K.M. Kosowska, R.S. Kozlov, L.S. Stratchounski, 

P.C. Appelbaum (Hershey, USA; Smolensk, RUS) 

P1144 Serotype and antimicrobial susceptibility of 

Streptococcus pneumoniae isolated in noninvasive 

disease in Portugal 

C. Pissarra, R. Dias, D. Louro, M. Caniça, 

GEMVSA (Lisbon, P) 

P1145 Antimicrobial susceptibility and serotype 

distribution of invasive Streptococcus 

pneumoniae isolated in Portuguese children 

under 5 years old (1999–2002) 

R. Dias, D. Louro, M. Caniça, GEMVSA 

(Lisbon, P)


P1146 Results of multicentre study of antimicrobial 

resistance of nasopharyngeal Streptococcus 

pneumoniae in children from day-care centres 

and orphanages in Asian Russia 

(SPARS-ASIA study) 

R.S. Kozlov, P.C. Appelbaum, K. Kosowska, 

O.I. Kretchikova, L.S. Stratchounski 

(Smolensk, RUS; Hershey, USA) 

P1147 Antimicrobial susceptibility of Streptococcus 

pneumoniae isolated from adults with acute 

sinusitis in three Russian centres 

L. Stratchounski, A. Tarasov, R. Kozlov, I. Edelstein, 

A. Kryukov, T. Alexanyan, A. Sedinkin, J. Yanov, 

D. Sergeev, O. Kretchikova, M. Sukhorukova 

(Smolensk, Moscow, St. Petersburg, RUS) 

P1148 Distribution of macrolide resistance 

mechanisms in Streptococcus pneumoniae: 

3-year update from the PROTEKT study 

D. Farrell, I. Morrissey 


P1149 Susceptibility of Streptococcus pneumoniae 

to penicillin, azithromycin and telithromycin 

(PROTEKT 1999–2002) 

G. Schito, D. Felmingham 


P1150 Serotype distribution and antimicrobial 

resistance of Streptococcus pneumoniae in 

Austria, 1996–2002: Implications for 

vaccination strategies 

A. Buxbaum, S. Forsthuber, W. Graninger, 

A. Georgopoulos – Austrian Bacterial Surveillance 

Network 

P1151 Tracking the activity of levofloxacin and 

comparator compounds against Streptococcus 

pneumoniae collected from five European 

countries during 2001–2002 and 2003 

R. Blosser, J. Karlowsky, D. Sahm, M. Jones 

(Herndon, USA) 

P1152 Antibiotic sensitivity and serotypes of 

S. pneumoniae isolates in blood culture 

during a 12-year period in a community-based 

hospital in Madrid, Spain 

M.D. Martín-Rodrigo, G. Seseña, 

S.M. Quevedo-Soriano, R. Jimenez, Y. Gil, 

J.M. del Álamo, A.C. Velasco, I. Wilhelmi 

(Leganés, E) 

P1153 Antimicrobial resistance among communityacquired 

respiratory tract infections in Brazil: 

PROTEKT 2002 

C. Mendes, C. Kiffer, J. Sampaio, C. Oplustil, 

C. Zoccoli, C. Dias, D. Farrell, D. Felmingham – 

PROTEKT Brazil Group 

P1154 Study of invasive penicillin-resistant 

pneumococci isolated in Romania between 

2000–2003 

M. Pana, M. Ghita, S. Iacob, O. Dorobat, 

R. Papagheorghe, N. Popescu, G. Bancescu, 

M. Andrei, V. Ungureanu, I. Nistor, S. Botea 

(Bucharest, RO) 

P1155 Analysis of macrolide-resistant isolates of 

Streptococcus pneumoniae gained from the 

Far East of Russia 

A. Martynova, V. Turcutyuikov (Vladivostok, RUS) 

P1156 Impact of telithromycin versus azithromycin 

on the nasopharyngeal microflora of patients 

with respiratory tract infections caused by 

pneumococci 

J.P. Guggenbichler, G. Juhl, R.B. Nieman, 

E. Wahlund, C.E. Nord (Erlangen, Munich, D; 

Bridgewater, USA; Stockholm, S) 

13:00–14:00 

Antibiotic therapy and public health issues 

P1157 Process costs of intravenous antibiotic 

therapy for community-acquired intraabdominal 

infections 

R. Andersson, G. Eckerwall, M. Nuijten, 

P. Engelfriet, S. Sen 

(Lund, S; Jisp, NL; Whitehouse Station, USA) 

P1158 Economic impact of S. pneumoniae macrolide 

resistance in children with acute otitis media 

in five European countries 

M. Sikirica, R. Mera, M. Higashi, J. Davidson 

(Collegeville, USA; Greenford, UK) 

P1159 Comparison of level of physician satisfaction 

with ertapenem, piperacillin/tazobactam and 

Cceftriaxone/metronidazole for the treatment 

of community-acquired intra-abdominal 

infections requiring surgery 

A. De La Pena, N. Navarro, W. Asperger, 

P. Mavros, C. Chan, M. Shivaprakash, S. Sen – 

OASIS Study Team 

P1160 Fixed-dose combination drugs for 

tuberculosis and HIV/AIDS: 

what are the issues? 

J. Primo-Carpenter (Rockville, USA) 


page 105


P1161 Association between inappropriate initial 

empiric antibiotic therapy and outcomes 

among patients undergoing surgery for 

community-acquired intra-abdominal 

infections in Israel 

A. Wertheimer, S. Sen 

(Philadelphia, Whitehouse Station, USA) 

P1162 Social and financial factors influencing 

rational use of antibiotics in Peru 

C. Kristiansson, M. Larsson, A. Thorson, 

E. Gotuzzo, L. Pachecco, H. Rodriguez Ferrucci, 

M. Reilly, E. Carvallo, A. Bartoloni, F. Bartalesi, 

M. Strohmeyer, A. Bechini, F. Paradisi, 

T. Falkenberg (Stockholm, S; Lima, Tarapoto, 

Iquitos, Yurimaguas, PE; Florence, I) 

P1163 Antibiotic consumption trends in the case of 

fever with unknown aetiology in the Turkish 

community 

N. Yapar, H. Tarakci, A. Sener, B. Karaca, O. Eren, 

A. Yuce (Izmir, TR) 

P1164 Analysis of urgency and effectiveness of postgraduate 

distance education on antimicrobial 

therapy in Russia 

I. Andreeva, V. Rafalski, O. Stetsiouk, B. Makushkin, 

A. Andreev, V. Kostin, G. Reschedko, 


P1165 Impact of an antibiotic policy in a community 

hospital 

E. Espejo, A. Basté, R. Busquets, M.A. Morera, 

E. Anoro, F. Bella (Terrassa, E) 

P1166 Costs of MRSA infection in a department of 

physical medicine and rehabilitation 

R. Boehmer, U. Wilhelm, A. Reiners, K. Perkuhn, 

H. Blaufuss (Munich, D) 

P1167 Evolution of the institutional antibiotic 

policies between 1999 and 2002 in French 

hospitals 

A.M. Rogues, C. Dumartin, P. Parneix, N. Marty, 

J.C. Labadie, J.P. Gachie (Bordeaux, Toulouse, F) 

P1168 The first three years of an outpatient and 

home parenteral antibiotic therapy (OHPAT) 

service in Glasgow 

R.A. Seaton, E. Bell, L. Semple (Glasgow, UK) 

P1169 Antibiotic prescribing knowledge among 

junior doctors - How can we improve it? 

H. Ziglam, S. Moitra, D. Morales, K. Webb, 

K. Gray, D. Nathwani (Dundee, UK) 


P1170 Antibiotic prophylaxis in severe acute 

pancreatitis: randomised multicentre 

prospective trial with meropenem 

S. Hejtmankova, J. Spicak, P. Cech, D. Hoskovec, 

R. Kostka, J. Leffler, M. Kasalicky, P. Svoboda, 

J. Bartova (Prague, CZ) 

P1171 Inventory and identification of lactic acid 

bacteria used as probiotics 

V. Vankerckhoven, T. Van Autgaerden, G. Huys, 

M. Vancanneyt, J. Swings, H. Goossens 

(Wilrijk, Ghent, B) 

P1172 Implementation of quality assurance 

programme for manually cleaned 

bronchoscopes following a pseudoepidemic 

of Mycobacterium chelonae 

M. John, J Vandierendonck, G. Peters, 

Z. Hussain, P. Chedore, G. Broukhanski 

(London, Ontario, CAN) 

P1173 Occupational sharp injuries and exposure to 

body fluids among health care workers 

A. Azap, Ö. Ergönül, K.-O. Memikoglu, 

A. Yesilkaya, A. Altunsoy, G. Yilmaz Bozkurt, 

E. Tekeli (Ankara, TR) 

P1174 Multicentre microbiological trials based on 

non-profit membership framework 

V.A. Kostin (Smolensk, RUS) 

P1175 Comparison of the different disinfecting 

capacities of contact lens solutions for rigid 

gas permeable lenses against ocular 

pathogens 

S.Y. Lai, M.M. O'Donoghue, M.V. Boost, 

P. Cho (Kowloon, HK) 

P1176 National electronic Library of Infection in the 

UK – can it change clinical practice? 

P. Kostkova, G. Madle, J. Weinberg, 

J. Mani-Saada (London, UK) 

P1177 Psychological aspects of needle-stick injury to 

health care workers in a teaching hospital 

J.W. Sohn, C.S. Han, S.H. Kim, M.J. Kim, 

H.J. Cheong, W.J. Kim, S.C. Park, S.I. Kim 

(Seoul, Ansan-si, Kyunggi-do, KOR)


P1178 Implementation of the ISO 9001: 

2000 standard in the Infectious Diseases 

Surveillance and Control Office of the 

Department of Public Health, Western Health 

Board, Ireland 

R. Cloughley, D. McKeown, O. McWeeney 

(Galway, IRL) 

P1179 The User Satisfaction Survey – an instrument 

to adjust and improve clinical microbiology 

services 

S. Hartvig Hartzen, H. Colding (Charlottenlund, 

Copenhagen, DK) 

P1180 Communication methods used for 

implementing antibiotic policy: 

a pilot project in Belgian hospitals 

L. Sourdeau, M.J. Struelens, W.E. Peetermans, 

C. Suetens and the Hospital Care Working Group 

of Belgian Antibiotic Policy Coordination 

Commitee (BAPCOC) 

13:00–14:00 

Antibiotic use and surveillance 

P1181 Reduction in outpatient antibiotic sales to 

pre-school children – interrupted time-series 

analysis of weekly antibiotic sales data in 

Sweden, 1992–2002 

L. Högberg, T. Oké, P. Geli, C. Stålsby Lundborg, 

K. Ekdahl, O. Cars (Solna, S) 

P1182 Blood cultures as a surrogate marker of casemix 

for adjustment of hospital antibiotic 

consumption 

F. Lamoth, P. Francioli, G. Zanetti (Lausanne, CH) 

P1183 Audit of the usage of broad-spectrum 

antibiotics in a Belgian university hospital: 

much room for improvement! 

B. Delaere, P.Y. Decleire, M. Bary, J.D. Hecq, 

Y. Glupczynski (Yvoir, B) 

P1184 Development of a paediatric Daily Defined 

Dose system for the measurement of 

antibiotic consumption in paediatric units 

C. Antachopoulos, J. Dotis, V. Pentsioglou, 

J. Evdoridou, E. Roilides (Thessaloniki, GR) 

P1185 The impact of multiresistance in risk factor 

analyses of antibiotic exposure among 

antimicrobial-resistant bacteria 

E. Tacconelli, M.A. Cataldo, R. Cauda, 

E.M.C. D'Agata (Rome, I; Boston, USA) 

P1186 Large-scale nationwide point prevalence 

study of indications for antibiotic use in 

54 Swedish hospitals in 2003 

G. Skoog, O. Cars, K. Skärlund, S. Elowson, 

H. Hanberger, I. Odenholt, M. Prag, J. Struwe, 

E. Torell, P. Ulleryd, M. Erntell – 

The STRAMA-program 

P1187 Antibiotic consumption in ambulatory care in 

Germany: a regional NUTS-I level analysis 

K. de With, H. Schröder, M. Steib-Bauert, K. Nink, 

W.V. Kern (Freiburg, Bonn, D) 

P1188 SARI - Surveillance of Antibiotic Use and 

Bacterial Resistance in German Intensive Care 

Units 

E. Meyer, D. Jonas, F. Schwab, H. Rüden, 

P. Gastmeier, F. Daschner 

(Freiburg, Berlin, Hannover, D) 

P1189 Reduction of antibiotic use by a communityoriented 

educational programme 

B. Chazan, R. Colodner, W. Sakran, N. Guy, 

R. Raz (Afula, IL) 

P1190 Evaluation of compliance to perioperative 

antibiotic prophylaxis guidelines 

I. Wybo, H. Vandenbussche, T. De Beer, 

D. Piérard, S. Lauwers (Brussels, B) 

P1191 Use of overnight processing of bacteriology 

samples to modify antibiotic prescribing 

habits in the community 

I.M. Gould, F.M. MacKenzie, L. Shepherd 


P1192 Influence of an antibiotic facilitator in a 

surgical unit 

I.M. Gould, E. O'Driscoll, B. Jappy (Aberdeen, UK) 

P1193 Perioperative antibiotic prophylaxis – 

adherence to local hospital guidelines 

V. Adamson, P. Mitt, H. Vestman, M. Maimets 

(Tartu, Pärnu, EST) 

P1194 Increase and change in patterns of hospital 

antimicrobial use, Denmark, 1997–2001 

M. Muscat, B. Müller-Pebody, B. Pelle, 

B.M. Klein, D.L. Monnet (Copenhagen, DK) 

P1195 Restricted antibiotic evaluation and 

pharmacoeconomics outcomes 

I. Gascón, F. Jover, J.M. Cuadrado, M.A. Pardo, 

T. Aznar, V. Ortiz de la Tabla, C. Martín, 

M. Martínez, M.D. Camacho (Alicante, E) 


page 107


P1196 Comparison of antimicrobial resistance in 

hospital-acquired and community-acquired 

bacteraemia 

R. Reynolds, N. Potz - BSAC Working Party on 

Bacteraemia Resistance Surveillance 

P1197 The impact of a nationwide antibiotic 

restriction policy on antibiotic usage and cost 

A. Azap, K.-O. Memikoglu, F. Cokca, E. Tekeli 

(Ankara, TR) 

P1198 The relation between Escherichia coli 

resistance and antibiotic consumption in 

Europe: an EARSS/ESAC study 

N. Bruinsma, M. Elseviers, P. Schrijnemakers, 

E. Tiemersma, J. Monen, R. Vander Stichele, 

H. Grundmann, H. Goossens 

and EARSS and ESAC participants 

P1199 Faecal carriage of quinolone-resistant E. coli 

in children in the community 

J. Shapira, M. Raz, N. Keller, B. Shainberg, 

N. Yavzori, E. Derazne, T. Halperin, G. Rahav, 

E. Rubinstein, G. Regev-Yochay 

(Ramat Gan, Rishon Lezion, IL) 

P1200 Laboratory and hospital reference data for 

validation of resistance data collected by 

the European Antimicrobial Resistance 

Surveillance System (EARSS) 

E.W. Tiemersma, N. Bruinsma, O. Lyytikäinen, 

K.G. Kristinsson, P. Schrijnemakers, J. Monen, 

J.E. Degener, H. Grundmann 

and EARSS participants 

13:00–14:00 

Vaccines and immunisation 

P1201 Modulation of immune response on 

ovalbumin sensitisation in BCG immunised 

mice 

W. Janaszek-Seydlitz, J. Michalkiewicz, 

B. Bucholc, P. Gorska (Warsaw, PL) 

P1202 Polyprenyls of plant origin augment specific 

biologic activity of tick-borne encephalitis and 

rabies vaccines 

S.V. Ozherelkov, R.S. Godunov, T.N. Kozhevnikova, 

A.N. Narovlyansky, A.V. Pronin, A.V. Sanin 

(Moscow, RUS) 

P1203 The assessment of three years of routine 

vaccination against Haemophilus influenzae 

b in the Czech Republic 

V. Lebedova, C. Benes, P. Kriz (Prague, CZ) 


P1204 Changes in distribution of pneumococcal 

serotypes in the Czech Republic between 

January 1996 and December 2003 

J. Motlova (Prague, CZ) 

P1205 Efficacy of a vaccine against Salmonella 

enteritidis based on Gantrez nanoparticles 

as adjuvant and delivery system 

C. Gamazo, J. Ochoa, J. Irache (Pamplona, E) 

P1206 The effects of gene deletions in recombinant 

vaccinia virus (rVV) genome on anticancer 

immunity induced by rVV based vaccine 

J. Macková, Sˇ. Nemecková, L. Kutinová, 

J. Krysˇtofová, P. Hainz, P. Otáhal, V. Sroller, 

P. Gabriel (Prague, CZ) 

13:00–14:00 

Antimicrobial susceptibility in Gram-negative 

bacteria – II 

P1207 Simple method to evaluate the in vitro 

activity of several antimicrobial agents 

against bacterial biofilms 

J. Alcalá, I. García, L. Martínez-Martínez, 

E.J. Perea, Á. Pascual (Seville, E) 

P1208 Antibiotic resistance markers in the 

Bacteroides fragilis group: 

clindamycin, cefoxitin, and trovafloxacin 

alone and in combination 

K. Aldridge, S. Broyles (New Orleans, USA) 

P1209 In vitro activities of BAL9141 and seven 

other beta-lactam antimicrobial agents 

towards clinical isolates of 12 members 

of the Enterobacteriaceae family 

M. Kresken, M. Heep (Bonn, D; Basle, CH) 

P1210 Drug resistance patterns of typhoidal 

and non-typhoidal Salmonella species in 

Hamadan, west of Iran 

R. Yousefi Mashouf (Hamadan, IR) 

P1211 Efficacy of crude extracts of Thai medicinal 

plants on antibiotic-resistant Helicobacter 

pylori strains isolated from peptic ulcers 

S.P. Voravuthikunchai, S. Brusentsev, 

J. O'Rourke, H. Mitchell 

(Hatyai, Songkla, TH; Sydney, AUS) 

P1212 French multicentre study of antibiotic 

resistance among Gram-negative anaerobes. 

Focus on decreased susceptibility to 

metronidazole 

L. Dubreuil, L. Calvet, F. Mory, C. Muller, M. Bezian, 

M. Chomarat, H. Jean-Pierre, S. Bland, T. Fosse, 

F. Golsdtein, H. Drugeon 

(Lille, Nancy, Paris, Bordeaux, Lyon, Montpellier, 

Annecy, Nice, Nantes, F)


P1213 Rate of capnophilic Gram-negative bacteria 

isolated from patients with periodontitis 

and study of their sensitivity to selected 

antibiotics 

M.H. Salari, M.H. Shirazi, R. Hafezi, G. Hassanpor 

(Tehran, IR) 

P1214 In vitro activity of colistin against nonfermentative 

Gram-negative bacilli 

Ö. Kurt Azap, H. Arslan, F. Ergin, S. Karaman, 

Ü. Cagir (Ankara, TR) 

P1215 Susceptibility testing of Stenotrophomonas 

maltophilia: effect of temperature and 

medium on results 

A. King (London, UK) 

P1216 Bactericidal activity of five antimicrobial 

agents against Campylobacter jejuni tested 

by time-kill studies 

J. Engberg, K. Schønning, M. Voldstedlund, 

E. Dzajic, N. Frimodt-Møller (Copenhagen, DK) 

P1217 The effect of subinhibitory concentrations 

(sub-MICs) of amikacin and ciprofloxacin on 

adherence of P-fimbriated Escherichia coli 

strains to human epithelial cells 

D. Wojnicz (Wroclaw, PL) 

P1218 Activity of meropenem against Gram-negative 

isolates from a Polish paediatric intensive 

care unit – part of the MYSTIC (Meropenem 

Yearly Susceptibility Test Information 

Collection) Programme, 1997–2003 

J. Patzer, D. Dzierzanowska, A. Pawiñska, 

P. Turner (Warsaw, PL; Macclesfield, UK) 

P1219 Stenotrophomonas maltophilia clinical 

isolates in a tertiary care hospital: 

5-year study 

E. Platsouka, A. Kallimani, E. Perivolioti, 

M. Dimoutsos, H. Belesiotou, O. Paniara 

(Athens, GR) 

P1220 Antimicrobial resistance in Campylobacter 

strains isolated from humans in Crete, Greece 

S. Maraki, E. Nioti, A. Georgiladakis, G. Samonis, 

Y. Tselentis (Heraklion, GR) 

P1221 In vitro activities of non-traditional anti - 

microbials against multiresistant strains of 

P. aeruginosa and A. baumanii isolated from 

intensive care units 

H. Arslan, O. Kurt Azap, F. Ergin, S. Ozbalikci 

Karaman, E. Oruc, F. Can, M. Demirbilek 

(Ankara, TR) 

P1222 Nosocomial infections by P. aeruginosa in 

Brazil – MYSTIC Program 2003 

C. Mendes, E. Sakagami, C. Oplustil, P. Turner, 

J. Sampaio, C. Kiffer (MYSTIC Brazil Group) 

P1223 Antimicrobial susceptibility of Bordetella 

bronchiseptica strains 

E. Rosales, G. Molina, G. Garza-Malacara, 

A. Fernandez-Ramirez, G. Barcenas-Morales, 

J. Montaraz-Crespo (Cuautitlan Izcalli, MEX) 

P1224 Postantibiotic effect of antimicrobial 

combinations on multiresistant Pseudomonas 

aeruginosa 

E.J. Giamarellos-Bourboulis, N. Kentebozidis, 

Z. Chryssouli, I. Galani, H. Giamarellou 

(Athens, GR) 

P1225 Achromobacter (Alcaligenes) bacteraemia: 

A 14-year retrospective analysis at a 

comprehensive cancer centre in the 

United States 

G. Aisenberg, A. Safdar (Houston, USA) 

P1226 In vitro susceptibility of antibiotic resistant 

Escherichia coli from urine samples to 

ertapenem and twelve other antibiotics 

A. Alhambra Mosquera, J. Cuadros, J. Cacho, 

J.-L. Gómez-Garcés, J.-I. Alós Cortés (Madrid, E) 

P1227 Susceptibility to ertapenem and other 

antibiotics of Amp-C producing 

enterobacteria isolated from urine samples 

A. Alhambra Mosquera, J. Cuadros, J. Cacho, 

J.-L. Gómez-Garcés, J.-I. Alós Cortés (Madrid, E) 

13:00–14:00 

Viral diseases 

P1228 Evaluation of measles-specific immunity in 

a high-risk group 

E.K. Bukin, A.V. Atrasheuskaya, S.N. Kameneva, 

N.L. Maksimov, A.P. Agafonov, G.M. Ignatyev 

(Koltsovo-Novosibirsk, RUS) 

P1229 Evaluation of oral fluid IgM, RT-PCR and 

genotyping for early diagnosis and 

characterisation of cases in Swiss measles 

outbreaks 

D. Burki, J.-L. Richard, M. Omeyer, K. Bir, 

C. Noppen, C. Schaefer, S. Santibanez, L. Matter 

(Basle, Berne, CH; Berlin, D) 

P1230 A measles outbreak in an ultra-orthodox 

partially immunised community 

C. Stein-Zamir, Z. Zentner (Jerusalem, IL) 

P1231 Serological screening for CMV antibodies 

during pregnancy: possibilities to select a 

high-risk group for congenital infection 

A. Naessens, A. Casteels, L. Decatte, 

S. Lauwers, W. Foulon (Brussel, B) 


page 109


P1232 Frequency of human papillomavirus infection 

among patients with chronic tonsillitis 

D. Velyvyte, A. Laiskonis, V. Uloza, A. Gozdzicka- 

Jozefiak (Kaunas, LIT; Poznan, PL) 

P1233 Detection of human papillomaviruses using 

PCR and sequence analysis in routine cervical 

cancer screening – Correlation of HPV type 

and cytology 

S. Kösel, S. Burggraf, W. Engelhardt, 

B. Olgemöller (Munich, D) 

P1234 Coxsackie viral infection in patients during 

1993–2002 

A. Petrovicova, S. Bopegamage, L. Barak 

(Bratislava, SK) 

P1235 Human enteroviruses in the treated 

wastewater of the Slovak Republic: 

a four year monitoring (1999–2003) 

Z. Sobotova, S. Blahova, S. Bopegamage 


P1236 The therapeutic effects of milrinone in 

treatment of enterovirus 71-induced 

pulmonary oedema 

C.-C. Liu, S.-M. Wang, H.-Y. Lei, M.-C. Huang, 

J.-M. Wu, C.-T. Chen (Tainan City, TW) 

P1237 Detection of the aetiological predominance 

of Norovirus in the hospital (nosocomial) 

gastroenteritis outbreaks in Hungary 

G. Reuter, K. Krisztalovics, B. van der Veer, 

E. de Bruin, H. Vennema, M. Koopmans, 

G. Szûcs (Pécs, Budapest, HUN; Bilthoven, NL) 

P1238 Molecular epidemiology of astrovirus 

infection in Italian children with 

gastroenteritis 

S. De Grazia, G.M. Giammanco, C. Colomba, 

L. Bonina, A. Cascio, S. Arista 

(Palermo, Messina, I) 

P1239 Incidence of Norwalk like viruses in stool 

samples of patients with gastroenteritis in 

the Tyrol, Austria 2002/2003 

F. Jax, B. Falkensammer, D. Orth, M. Dierich, 

H. Stoiber (Innsbruck, A) 

P1240 The investigation of parvovirus B19 infection 

in patients with haematologic disorders and 

chronic anaemia by using PCR and ELISA 

T. Us, L. Ozunel, Y. Akgun, Z. Gulbas 

(Eskisehir, TR) 

P1241 The relationship between arthritis and 

parvovirus B19 infection 

B. Kocazeybek, R. Caliskan, S. Masatlioglu, 

M. Aslan, S. Altun, S. Saribas, S. Ergin, E. Uckan, 

V. Köksal, K. Altas, I. Fresko (Istanbul, TR) 


P1242 Immunodetection of Parvovirus B19 virus 

in human plasma: appraisal of a novel 

fluorometric immunoassay and comparison 

with an enzyme immunoassay 

F. Loftus, S. O'Keeffe, S. Doyle, D. O'Leary, 

G. Elliott, S. Kerr (Dublin, Kildare, IRL) 

P1243 Crimean Congo haemorrhagic fever (CCHF), 

the main aetiological cause of viral 

haemorrhagic fevers in the last four years 

(2000–2003) in Iran 

S. Chinikar, A. Fayaz, R. Mirahmadi, V. Mazaheri, 

F. Ahmadnejad, M. Gooya, B. Hooshmand, 

P. Nabeth, M.F. Saron (Tehran, IR; Dakar, SN) 

P1244 Crimean Congo haemorrhagic fever in 

Sistan and Baluchestan province of Iran, 

a case-control study 

S. Izadi, K. Holakouie Naieni, S.R. Madjdzadeh, 

A. Nadim (Zahedan, Tehran, IR) 

P1245 Detection of IgG and IgM antibodies vs West 

Nile virus 

E. Anastasakou, P. Duramani, C. Kapotis, 

S. Mavrea (Athens, GR) 

P1246 Comparison of tick-borne encephalitis 

incidence in the Czech Republic under 

extreme weather conditions in 2001–2003 

V. Danielova, M. Daniel, B. Kriz, C. Benes, 

K. Zitek (Prague, CZ) 

P1247 Tick-borne encephalitis risk forecast based on 

climate and microclimate factors affecting 

the activity of vector Ixodes ricinus tick 

M. Daniel, K. Zitek, V. Danielova, B. Kriz, J. Valter, 

I. Kott (Prague, CZ) 

P1248 A qualitative detection of tick-borne 

encephalitis in clinical samples by real-time 

PCR 

E. Zamapchova, V. Cihlarova (Ceske Budejovice, CZ) 

P1249 Changes in diagnostics and treatment of 

tick-borne encephalitis 

V. Struncova, D. Sedlacek, M. Svecova, 

P. Pazdiora (Pilsen, CZ) 

P1250 Severe courses of tick-borne encephalitis in 

Ostrava, 1999–2003 

A. Zjevikova, I. Orsagova, L. Roznovsky, 

J. Januska (Ostrava, CZ) 

P1251 Purification and analysis of the structure of 

prion aggregates from yeast Saccharomyces 

cerevisiae 

D. Kryndushkin, I. Alexandrov, V. Kushnirov, 

M. Ter-Avanesyan (Moscow, RUS)

13:00–14:00 

Diagnostic methods – II 


P1252 Evaluation of the VCAT3 Neisseria selective 

medium 

T. Tirczka, M. Gacs, M. Füzi (Budapest, HUN) 

P1253 A rapid antigenic test combined with a sore 

throat score versus culture in group A 

streptococcal pharyngitis 

C.S. Stingu, T. Turcu (Iasi, RO) 

P1254 Comparison of five media for detection of 

group B Streptococci in vaginal/rectal swabs 

from pregnant women 

L. Stoakes, S. Burn, M. Myers, M. John, 

Z. Hussain (London, Ontario, CAN) 

P1255 Usefulness of fatty acid analysis for 

identification of nutritionally variant 

streptococci 

E. Durnová, I. Porazilová, J. Jancová, G. Novotná 

(Ostrava, Prague, CZ) 

P1256 Evaluation of the SM ID 2 medium: 

comparison to the SM ID, BBL CHROMagar 

Salmonella and Hektoën media 

J-Y. Dusseau, P. Gérôme, J. Bougere, S. Orenga, 

D. Robichon, C. Roger-Dalbert 

(Lyon, La Balme les Grottes, F) 

P1257 Shewanella species: infections in Denmark 

and phenotypic characterisation 

H.M. Holt, B. Gahrn-Hansen, B. Bruun 

(Odense, Hillerød, DK) 

P1258 Simple sample preparation methods to detect 

Shiga-toxin-producing E. coli from human 

stools by Duopath Verotoxin 

C. Park, H. Schmidt, A. Ditzen, D. Murphy, 

A. Bubert (Falls Church, USA; Dresden, D; 

Brisbane, AUS; Darmstadt, D) 

P1259 The biological characterisation of new phage 

types of Salmonella enterica serovar 

Enteritidis 

V. Majtán, L. Majtánová (Bratislava, SK) 

P1260 Phage typing of Salmonella enterica serovar 

Typhimurium isolated from humans in the 

Slovak Republic, 2000–2003 

L. Majtánová, V. Majtán (Bratislava, SK) 

P1261 Comparison of culture methods for isolation 

and enumeration of Legionella species from 

cooling tower water samples 

P.G.H. Peerbooms, J.D. Schalekamp, A.A. Bartels 

(Amsterdam, Rotterdam, NL) 

P1262 Clinical study of a new chromogenic medium 

for the isolation and the direct identification 

of Staphylococcus aureus 

M-E. Reverdy, C. Roger-Dalbert, D. Robichon, 

J. Etienne (Lyon, La Balme les Grottes, F) 

P1263 Detection of Helicobacter pylori: 

evaluation of staining methods 

T. Babic, H. Basic, B. Miljkovic Selimovic, 

B. Kocic (Nis, CS) 

P1264 Antibiotic-associated colitis: value of colonic 

ultrasound in diagnosis and follow-up 

L. Tarantino, A Giorgio, G. de Stefano, V. Scala, 

A. Di Sarno, G. Liorre, P. Sorrentino, A. Sullo 

(Naples, I) 

P1265 Can the use of a microbiological screen of 

dental implants predict implant failure? 

C. Smith, E. Nyako, A. Preston, C. Watson, 

J. Dave (Leeds, UK) 

P1266 Acute primary diagnosis of malaria on 

medical wards in a non-endemic country 

using the Binax Pf/Pv ( R ) rapid antigen 

detection test 

L. Wiese, A. Friis-Møller, H. Fjeldsøe-Nielsen, 

J. Hansen, T. Hornstrup, B. Bruun, O. Heltberg, 

T. Højbjerg, G. Gomme, J. Kurtzhals 

(Copenhagen, Hvidovre, Hillerød, Odense, 

Næstved, Aalborg, DK) 

P1267 Differentiation of Candida albicans from 

other yeast species using a new, simple and 

non-hazardous biochemical test kit 

A. Brown, B. De Caux, P. Druggan, S. Hall, 

P. Stephens (Basingstoke, UK) 

P1268 Identification of chlamydial antigens by 

means of the phage surface display technique 

C. Hermann, M. Müller, S. Michelfelder, 

T. Hartung (Constance, D) 

P1269 Detection of Chlamydophila pneumoniae in 

acute exacerbation of COPD patients by 

real-time PCR and MIF test 

Y. Uyar, M. Günaydin, C. Eroglu, A. Karadag, 

A. Karayunus, L. Erkan, S. Canbaz (Samsun, TR) 

P1270 Isolation and characterisation of oral 

Actinomyces species from patients with 

periodontal diseases 

S. Eshraghi, M.H. Shirazi, S. Yaghmaei 

(Tehran, IR) 

P1271 Evaluation of a new Oxoid ELISA for the 

detection of enteric adenoviruses 

J. Cloke, D. Hirst, A. Hole, A. Parker 

(Basingstoke, Bristol, UK) 


page 111


P1272 Evaluation of a new Oxoid ELISA for the 

detection of rotavirus 

J. Cloke, D. Hirst, A. Hole, A. Parker 

(Basingstoke, Bristol, UK) 

13:00–14:00 

Mycobacterial disease: pathogenesis and 

therapy 

P1273 Reaction to cheese during tuberculosis 

treatment 

A. Carvalho, M. Manfrin, R. Poni Gore, 

S. Capone, S. Caligaris, A. Armellini, T. Giovine, 

A. Matteelli, G. Carosi (Brescia, I) 

P1274 The predictive value of serum procalcitonin 

levels in patients with pulmonary 

tuberculosis 

O. Baylan, A. Balkan, A.S. Inal, O. Kisa, A. Albay, 

L. Doganci (Ankara, TR) 

P1275 Determination of IL-4,IL-6,IL-8 interleukins 

and TNF-a in patients with tuberculosis 

during treatment 

C. Kapotis, M. Dimadi, S. Mavrea, I. Tsiaras, 

D. Alepopoulou, E. Kosmaoglou, E. Aanastasakou 

(Athens, GR) 

P1276 Intracellular growth of clinical isolates of 

M. tuberculosis with different ability of 

dissemination 

L. Folgueira, A. Boluda, F. Chaves, E. Palenque, 

J.R. Otero (Madrid, E) 

P1277 Sigma factors and hspX expression could be 

markers of stress adaptation and reactivation 

of growth of Mycobacterium tuberculosis in 

acidified cultures 

S. Gordillo, J. Díaz, I. Amat, E. Guirado, S. Molinos, 

C. Vilaplana, V. Ausina, P.J. Cardona (Badalona, E) 

P1278 The effects of azathioprine and prednisolone 

on cytokine expression in the skin and blood 

of severe leprosy type 1 reaction patients 

S.N.S. Marlowe, S. Khanolkar-Young, 

R. Manandhar, N. Shrestha, P.W. Roche, 

M. Macdonald, P.G. Nicholls, D.N.J. Lockwood 

on behalf of Follereau Luxembourg, LEPRA 

P1279 Serum total adenosine deaminase level in 

active pulmonary tuberculosis in comparison 

to other infectious diseases in Iran 

S. Amini Afshar, L. Gachkar, Ma. Keshtkar 

Jahromi, B. Haghighat, Mi. Keshtkar Jahromi 

(Tehran, Shiraz, IR) 


P1280 Paradoxical response in infliximab-treated 

patients with disseminated tuberculosis 

C. Garcia Vidal, S. Rodríguez Fernández, 

J. Martínez Lacasa, M. Salavert, R. Vidal, 

M. Rodríguez Carballeira, J. Garau 

(Terrassa, Valencia, Barcelona, E) 

P1281 Long-term efficacy of a six-month treatment 

regimen (6HR2Z) for HIV-negative tuberculous 

meningitis 

J.F. García Rodríguez, R. de la Fuente-Fernández, 

M.V. Lorenzo García, A. Fernández Rial, 

A. Mariño Callejo, P. Sesma Sánchez (Ferrol, E) 

P1282 Mycobacterium tuberculosis complex sigma 

factor H gene expression during pulmonary 

tuberculosis treatment 

S. Dworniczak, J. Pendzich, W. Mazur, U. Mazurek, 

G. Niepsuj, J. Kieda-Szurkowska, D. Ziora, 

J. Kozielski (Zabrze, Sosnowiec, PL) 

13:00–14:00 

Mycobacterial disease: multiresistant 

tuberculosis 

P1283 Diagnosis of multiresistant tuberculosis by 

detection of mutations in rpoB and inhA by 

real-time PCR 

L. Brum, T. Ramos, L. Barreiro, E. Pereira 

(Lisbon, P) 

P1284 Can phenotypic susceptibility testing for 

M. tuberculosis be performed before 

identification? 

Ó. Pérez-Olaso, M.J. Ruiz-Serrano, 

N. García-Escribano, M. Marín-Arriaza, 

D. García de Viedma, E. Bouza (Madrid, E) 

P1285 Antimicrobial susceptibilities of 

Mycobacterium tuberculosis strains isolated 

from clinical specimens in Crete, Greece 

Z. Gitti, S. Maraki, F. Kontos, I. Kyriakakis, 


P1286 Malnutrition in multidrug resistant 

tuberculosis patients in the Philippines 

V. Antonios, I. Sia, J. St. Sauver, R. Orillaza, 

M. Quelapio, T. Tupasi 

(Rochester, USA; Makati City, Manilla, PH) 

P1287 Resistance problem in Mycobacterium 

tuberculosis: evaluation of the resistance of 

166 M. tuberculosis strains against four 

major drugs 

S. Saribas, Y. Bagdatli, N. Yildiz, Ö. Yigit 

(Istanbul, TR)


P1288 Recovery rate and drug resistance of 

mycobacterial strains by the BACTEC 460TB 

system during 2001-2003 in Kocaeli, Turkey 

S. Günde, E. Karaali, A. Willke (Kocaeli, TR) 

P1289 Drug resistance rates of M. tuberculosis 

strains from civilian and prison patients in 

Samara region, Russia 

Y. Balabanova, M. Ruddy, S. Kuznetsov, 

I. Fedorin, A. Melentyev, S. Zakharova, 

N. Malomanova, E. Elizarova, V. Nikolayevskyy, 

J. Hubb, F. Drobniewski 

(London, UK; Samara, RUS; Odessa, UKR) 

P1290 Multicentre study on Mycobacterium 

tuberculosis susceptibility testing using 

BacT/ALERT automatic system 

A. Ortega Calderon, M.A. Lezcano, A. Alberte, 

J. Garcia (Madrid, Zaragoza, Valladolid, E) 

P1291 Detection of mutations at embB codons 306 

and 497 and iniA codon 501 by PCR-RFLP 

for rapidly determining resistance to 

ethambutol in ethambutol-resistant clinical 

Mycobacterium tuberculosis isolates 

S. Ahmad, E. Mokaddas, A.-A. Jaber (Safat, KWT) 

P1292 Molecular characterisation of isoniazidresistant 

Mycobacterium tuberculosis strains 

from the Free State and Northern Cape 

provinces, South Africa 

A. van der Spoel van Dijk, M.N. Janse van 

Rensburg, S.Z. Mokhethi, A.G.M. van der Zanden 

(Bloemfontein, ZA; Apeldoorn, NL) 

P1293 rpoB mutations in rifampin-resistant clinical 

Mycobacterium tuberculosis isolates from 

Turkey 

Z.C. Karahan, F. Atalay, M. Uzun, Z. Erturan, 

M. Atasever, N. Akar (Ankara, Istanbul, TR) 

P1294 Use of PCR-SSCP for rapid detection of 

rifampin and isoniazid resistance-associated 

mutations in Mycobacterium tuberculosis, 

isolated in Suez Canal region, Egypt 

M. El-Sweify, A. Heiba, F. Ibrahim, S. Abbadi, 

K. Ibrahim, N. Gomaa, R. Cooksey 

(Ismailiya, EGY; Atlanta, USA) 

P1295 Tuberculosis caused by multiresistant strains 

of Mycobacterium tuberculosis in the Czech 

Republic. Microbiological, epidemiological 

and DNA analysis 

M. Havelková, L. Charvatova, V. Príkazsky‘ 

(Prague, CZ) 

13:00–14:00 

Miscellaneous issues 

P1296 Chlorination of bacterial surfaces by 

N-chlorotaurine 

M. Nagl, W. Gottardi (Innsbruck, A) 

P1297 Amelioration of the prokinetic effect of 

erythromycin on oesophageal motility by 

atropine 

A.Z. Helaly, M.A. Shaat, S.E. Rewini 

(Alexandria, EGY) 

P1298 Impact of prolonged treatment with 

trimethoprim-sulfomethoxazole on the 

human gut flora 

D. Kofteridis, S. Maraki, D. Alegakis, 

N. Tsagarakis, E. Barbounakis, G. Samonis 

(Heraklion, GR) 

P1299 Ecological effects of pivmecillinam on the 

normal vaginal microflora 

Å. Sullivan, M. Karlsson, M. Ström, L. Ydenius, 

A. Fianu-Jonasson, B.-M. Landgren, C.E. Nord 

(Stockholm, S) 

P1300 Risk of adverse birth and neonatal outcomes 

for pregnant users of pivmecillinam – 

a population-based cohort study 

M.V. Skriver, M. Nørgaard, L. Pedersen, 

H.C. Schønheyder, H.T Sørensen 

(Aarhus, Aalborg, DK) 

P1301 Influence of ertapenem on cell activation and 

co-stimulatory molecule expressions 

I. Korzh, V. Nemtsova, I. Fedotova (Kharkov, UKR) 

13:00–14:00 

Paediatric infections 

P1302 Risk factors for candidiasis in the neonatal 

unit: a matched case-control study 

C. Antachopoulos, K. Patel, B. Sprague, B. Short, 

J. Campos, N. Singh (Washington, USA) 

P1303 Secular trends in aetiology of neonatal sepsis 

(1991–2001) 

K. Bindayna, A. Jamsheer, E. Farid, G. Botta 

(Manama, BH) 

P1304 Investigation of Streptococcus pyogenes 

strains isolated from children with fatal STSS 

L. Zachariadou, A. Charissiadou, H. Barbaressou, 

A. Tanna, A. Efstratiou, A. Hatzis, A. Pangalis 

(Athens, GR; London, UK) 


page 113


P1305 Beneficial effects of immediate treatment of 

group A beta-hemolytic streptococcal 

pharyngitis with antibiotics 

N. Salman, M.A. Talay, A. Somer, I. Yalcin 


P1306 An evaluation of once daily cefdinir 25 mg/kg 

oral suspension in children with acute otitis 

media at risk of persistent or recurrent otitis 

media 

E. Leibovitz, R. Dagan, A. Arguedas, A. Hoberman, 

M. Pichichero, T. Busman, M. Paris, S. Bukofzer – 

The Cefdinir M01-352 Study Group 

P1307 Epidemiology of Streptococcus pneumoniae 

causing acute otitis media in young children 


R. Prymula, P. Kriz, J. Motlova, V. Chrobok 

(Hradec Kralove, Prague, Pardubice, CZ) 

P1308 Invasive serotypes of Streptococcus 

pneumoniae in nasopharynx of healthy 

children 

I. Korona-Glowniak, A. Malm (Lublin, PL) 

P1309 Resistance profile of S. pneumoniae and 

beta-lactamase production in H. influenzae 

and M. catarrhalis isolated from 258 children 

with upper respiratory tract infection in 

southern Brazil – 2002 

C. Mendes, C. Zoccoli, F. Rossi, G. Duboc, 

P. Garbes, L. Pedneault, J. Sampaio, C. Kiffer 

(Sao Paulo, Florianopolis, Rio de Janeiro, BR; 

Brussels, B) 

P1310 Streptococcus agalactiae: vaginal and rectal 

carriage in females in childbirth, incidence of 

early-onset disease, distribution of serotypes, 

susceptibility to antimicrobials 

J. Motlova, L. Strakova, P. Urbaskova, M. Hanzl, 

P. Sak, M. Balejova, T. Sever, M. Bartova 

(Prague, Ceske Budejovice, CZ) 

P1311 Sorbitol non-fermenting E. coli strains in 

children with acute diarrhoea 

X. Agathocleous, A. Makri, I. Varzakakos, 

G. Kanellopoulou, M. Varvery, H. Papavasileiou 

(Athens, GR) 

P1312 Rickettsia typhii infection in children in 

Cyprus 

C. Georgiou, M. Koliou, A. Hadjipanayis, 

N. Persianis, P. Zarvos, C. Hadjichristodoulou, 

M. Theodoridou, C. Kattamis – 

Paediatric Surveillance Unit Cyprus-Greece 


P1313 Genomovar status and antibiotic resistance of 

Burkholderia cepacia complex isolates in 

cystic fibrosis centre in Kosice, Slovakia 

Y. Navesnakova, P. Drevinek, O. Cinek, 

L. Tkacikova (Kosice, SK; Prague, CZ) 

P1314 Late clearance of viraemia in four perinatally 

HCV-infected children: should the concept 

of HCV infection chronicity be revised in 

paediatrics patients? 

G. Bossi, E. Minola, C. Lazzaroni, B. Salati, 

A. Maccabruni (Pavia, Bergamo, I) 

13:00–14:00 

Immunology and immunotherapy 

P1315 Kinetics of the release of nitric oxide and 

tumour necrosis factor-alpha after activation 

of microglia via Toll-like receptors-2, -4, and -9 

S. Ebert, J. Gerber, S. Bader, F. Mühlhauser, 

T. Mitchell, R. Nau (Goettingen, D; Glasgow) 

P1316 Drug modulation of Toll-like receptors 

expression by human macrophages 

stimulated with lipopolysaccharide and 

bacteria 

O. Beran, D. Lawrence (Albany, USA) 

P1317 Exopolysaccharides from marine thermophilic 

bacilli induce a Th1 cytokine profile in human 

PBMC 

A. Arena, B. Pavone, C. Gugliandolo, T.L. Maugeri, 

G. Bisignano (Messina, I) 

P1318 Differential induction of IL-8 expression by 

LPS and LTA 

R. Munke, L. Hareng, S. von Aulock, T. Hartung 

(Constance, D) 

P1319 Mannose-binding lectin and susceptibility to 

infection in pre-term neonates 

A.B. Dzwonek (London, UK) 

P1320 Immunotherapy with RUTI, a new useful 

vaccine for treatment of Mycobacterium 

tuberculosis infection 

P.J. Cardona, I. Amat, S. Gordillo, V. Arcos, 

E. Guirado, J. Díaz, G. Fernández-Rivas, G. Tapia, 

V. Ausina (Badalona, E) 

P1321 Coadministration of intranasal RUTI with 

chemotherapy improves the treatment of 

Mycobacterium tuberculosis infection 

P.J. Cardona, I. Amat, S. Gordillo, V. Arcos, 

E. Guirado, J. Díaz, A. Pallarés, G. Tapia, 

V. Ausina (Badalona, E)


P1322 Early prognostic markers of outcome in 

severe sepsis 

A. Lekkou, M. Karakantza, A. Mouzaki, D. Siagris, 

F. Kalfarentzos, H.P. Bassaris, C.A. Gogos 

(Patras, GR) 

P1323 Evaluation of cardiac troponin I in elderly 

patients with sepsis 

N. Komitopoulos, N. Lionakis, A. Giakoumaki, 

I. Ioannidis, P. Paraskeuopoulou, D. Avramidis, 

A. Komitopoulou, E. Varsamis (Athens, GR) 

13:00–14:00 

Host defenses 

P1324 Influenza and Sendai viruses induce a 

differential IFN, chemokine and IKKe gene 

expression in A549 lung epithelial cells 

S. Matikainen, V. Veckman, J. Pirhonen, 

P. Österlund, J. Siren, J. Hiscott, G. Uze, 

M. Severa, I. Julkunen 

(Helsinki, FIN; Montreal, CAN; Montpellier, F) 

P1325 Monoclonal antibodies against recombinant 

spike protein neutralise the infection of 

severe acute respiratory syndrome 

coronavirus (SARS-CoV) through inhibition 

of virus binding to vero E6 cells 

Y.C. Wang, S.C. Lai, C.T. Yeh, J.T. Jan, H.W. Liu 

(Taipei, TW) 

P1326 Interaction of respiratory tract pathogens and 

epithelial cells 

C. Kratzer, W. Graninger, A. Georgopoulos 

(Vienna, A) 

P1327 Role of dendritic cells in the immune 

regulation of primary Epstein-Barr virus 

infection 

O.H. Wong, F.P. Huang, A.K.S. Chiang 

(Hong Kong, HK) 

P1328 Role of endogenous tumour necrosis 

factor alpha and beta on cytomegalovirus 

replication in human placental cells 

E. Paradowska, M. Studzinska, D. Nowakowska, 

J. Wilczynski, Z.J. Lesnikowski (Lodz, PL) 

P1329 Assessment of the correlation between 

anti-inflammatory therapy and concentration 

of pro-inflammatory cytokines in cerebro - 

spinal fluid and its effect on the outcome of 

bacterial meningitis 

M. Bociaga-Jasik, A. Garlicki, A. Kalinowska- 

Nowak, T. Mach (Cracow, Warsaw, PL) 

P1330 Complement activation during meningococcal 

disease: engagement of alternative and 

lectin pathway and association with disease 

severity 

T. Sprong, T.E. Mollnes, C. Neeleman, 

J.W.M. van der Meer, M. van Deuren 

(Nijmegen, NL; Oslo, N) 

P1331 The importance of cytokine and cortisol levels 

in cerebrospinal fluid as clinical and biological 

markers of bacterial meningitis 

M. Holub, O. Beran, J. Hnyková, D. Lawrence, 

O. Dzupová, Z. Lacinová 

(Prague, CZ; Albany, USA) 

P1332 Two-year follow-up analysis of the classspecific 

immune response after infection with 

Yersinia pseudotuberculosis followed by 

erythema nodosum and reactive arthritis – 

case report 

W. Rastawicki, M. Jagielski, R. Gierczyñski, 

J. Buratowska (Warsaw, PL) 

P1333 Pro-inflammatory cytokine production by 

human monocytes in response to 

P. aeruginosa infection mainly involves TLR2 

and Mannose receptor 

P. Xaplanteri, G. Lagoumintzis, G. Dimitracopoulos, 

F. Paliogianni (Patras, GR) 

P1334 Pseudomonas aeruginosa LPS and slime 

glycolipoprotein differentially activate the 

same mitogen-activated protein kinase 

signalling pathways for tumour necrosis 

factor alpha in fresh human monocytes 

G. Lagoumintzis, P. Xaplanteri, G. Dimitracopoulos, 

F. Paliogianni (Patras, GR) 

P1335 In vitro stimulation of innate immunity by 

susceptible and resistant Escherichia coli 

M. Bristianou, A. Antonopoulou, D. Plachouras, 

A. Tzivra, H. Giamarellou, E.J. Giamarellos- 


P1336 The role of human beta-defensins during 

Campylobacter jejuni infection 

M. Zilbauer, N. Dorrell, J.T. George, P.K. Boughan, 

M. Bajaj-Elliott (London, UK) 

P1337 Association between Helicobacter pylori 

infection and chronic idiopathic urticaria 

M. Marcano, M. Urrestarazu, N. Serrano, 

M.E. Cavazza Porro, D. Ortiz, O. Rodriguez 

(Caracas, VE) 

P1338 Some biochemical and serological aspects of 

Q fever diagnosis 

K. Slaba, L. Skultety, R. Toman (Bratislava, SK) 


page 115


P1339 Evaluation of inflammatory capacity of fungal 

spores in human whole blood 

M. Daneshian, I. Kindunger, T. Gabrio, T. Hartung, 

S. von Aulock (Constance, Stuttgart, D) 

P1340 The differentiation of human monocytes into 

dendritic cells is tunable and exploitable by 

micro-organisms to modulate the host’s 

adaptive immune response: 

the Candida albicans model 

G. Romagnoli, A. Torosantucci, A. Stringaro, 

P. Chiani, S. Mariotti, G. Arancia, A. Cassone, 

R. Nisini (Rome, I) 

P1341 Monocyte chemotactic protein-1 production 

by human astrocytes and astrocytoma cell 

lines during toxoplasmic infection: differential 

regulation by interferon-gamma and D-609 

F. Durand, M. Brenier-Pinchart, J. Simon, 

P. Marche, F. Berger, H. Pelloux (Grenoble, F) 

P1342 Yersinia toxin YopE Targets granulocytes in 

the intestinal tract and associated lymphatic 

tissues 

J.M. Balada Llasat, I. Basu, M. Guerau-de-Arellano, 

J. Mecsas (Boston, USA; Auckland, NZ) 

13:00–14:00 

Nosocomial infections: 

Gram-positive micro organisms 

P1343 Surveillance of glycopeptide-resistant 

enterococcal bacteraemias in England 

D. Brown, N. Brown, B. Cookson, G. Duckworth, 

M. Farrington, G. French, L. King, D. Lewis, 

D. Livermore, B. Macrae, G. Scott, D. Williams, 

N. Woodford – GRE Bacteraemia Surveillance 

Working Group 

P1344 Epidemiology of vancomycin-resistant 

enterococci in a Greek tertiary hospital: 

comparison of two point prevalence studies 

on intestinal colonisation 

A. Christidou, A. Gikas, E. Scoulica, G. Minadakis, 

M. Dialynas, I. Kyriakakis, M. Roumpelaki, 

J. Pediaditis, A. Georgiladakis, Y. Tselentis 

(Heraklion, GR) 

P1345 Clonal dissemination of van A-type 

glycopeptide-resistant Enterococcus faecalis 

between hospitals located in two cities in 

the State of Sao Paulo, Brazil 

M.L. Moretti, O.J. Bratfich, R.B. Stucchi, 

C. Levi, A.S. Levin, G. Duboc, E. Vormittag, 

D. Blum-Menezes (Sao Paulo, BR) 


P1346 Virulence factors and antimicrobial resistance 

in Enterococcus faecalis strains of clinical 

origin 

S. Cosentino, A. Corda, G.S. Podda, M.B. Pisano, 

T. Pisanu, M.E. Fadda (Monserrato, Cagliari, I) 

P1347 Five-year molecular epidemiology of highlevel 

gentamicin-resistant Enterococcus 

faecalis in a Belgian academic hospital 

E. Prospero, A. Deplano, C. Nonhoff, F. Rost, 

B. Byl, M.J. Struelens (Ancona, I; Brussels, B) 

P1348 Epidemiology and antimicrobial patterns 

of multiresistant nosocomial strains of 

Enterococcus faecium isolated over three 

years in a Bulgarian university hospital 

N. Hadjieva, N. Hadjieva, D. Ivanova (Sofia, BG) 

P1349 Hospital and community-acquired 

Staphylococus aureus bacteraemia: 

risk factors, location of inflammation 

and outcome 

E. Kalogeropoulou, L. Mourgos, P. Tsiodra, 

M. Belechri (Athens, GR) 

P1350 Endocarditis is not a common complication 

of catheter-related Staphylococcus aureus 

bacteraemia 

R. Finkelstein, I. Oren, I. Kassis, E. Braun, 

I. Mogilewski, S. Edelstein, F. Nakhoul, 

H. Sprecher, A. Raz, Y. Agmon, S. Reisner 

(Haifa, IL) 

P1351 Characteristics of staphylococci from hip 

prostheses infections 

A. Longauerova, D. Kotulova, L. Slobodnikova, 

F. Ruzicka (Bratislava, SK; Brno, CZ) 

P1352 Five-year review of Staphylococcus aureus 

bloodstream infections in renal patients, 

1998–2002 

S.F. FitzGerald, F.M. Fitzpatrick, R. Crowley, 

H. Humphreys, E.G. Smyth (Dublin, IRL) 

P1353 Antimicrobial resistance of nosocomial 

strains of S. aureus isolated from patients 

with skin and soft tissue infections in Russia 

A. Dekhnich, L. Stratchounski, I. Edelstein 


P1354 Staphylococcus hominis subsp. 

novobiosepticus – New pathogen in 

nosocomial infections 

M. Balejova, P. Petras 

(Ceske Budejovice, Prague, CZ) 

P1355 Pathogenic Staphylococcus epidermidis 

bloodstream isolates: PFGE analysis and 

biofilm formation 

B. Parschalk, H. Adametz, F. Yassin, 

A.-M. Hirschl, W. Graninger, E. Presterl 

(Vienna, A)


P1356 Resistance profiles in biofilm-positive strains 

of Staphylococcus epidermidis isolated from 

blood cultures 

V. Hola, F. Ruzicka, R. Tejkalova, M. Votava 

(Brno, CZ) 

P1357 Staphylococcus lugdunensis: 

an emerging pathogen in bone and joint 

infections? Report of 17 cases 

S. Khatibi, E. Bonnet, M. Archambaud, 

G. Giordano, B. Chaminade, P. Bonnevialle, 

C. Cauhepe, R. Bauriaud, B. Marchou, P. Massip 

(Toulouse, F) 

13:00–14:00 

Nosocomial infections: 

multiresistant Gram-negative bacteria 

P1358 Clinical presentation and outcome of 

multi-resistant Enterobacter aerogenes 

infections: a review of 116 episodes 

J. Frankard, B. Byl, H. Rodriguez-Villalobos, 

C. Mélot, J.-L. Vincent, M. Struelens, F. Jacobs 

(Brussels, B) 

P1359 ESBL-producing Enterobacter aerogenes 

outbreak in neonates hospitalised in a 

neonatal unit 

J. Komarnicka, T. Czajkowska, I. Domzalska- 

Popadiuk, B. Rybak, A. Thrun, E. Czarniak, 

A. Samet, J. Szczapa (Gdansk, PL) 

P1360 Study of antibiotic resistance, production 

of ESBL and other virulence factors in 

enterobacterial strains isolated from 

nosocomial infections in cardiovascular 

devices inserted patients 

V. Lazar, O. Banu, C. Balotescu, R. Cernat, 

A. Cotar, O. Dracea, C. Bleotu (Bucharest, RO) 

P1361 Urinary pathogens in a general hospital 

in Greece: antimicrobial resistance and 

incidence of ESBL producing strains during 

2001–2003 

F. Markou, A. Poulou, F. Mountaki, X. Efthimiou 

(Serres, GR) 

P1362 Clinical and epidemiological analysis of 

Klebsiella pneumoniae bacteraemia in a 

neonatal department 

E. Czarniak, J. Komarnicka, A. Sledzinska, 

A. Samet, J. Kur, J. Szczapa (Gdansk, PL) 

P1363 Molecular epidemiology of ESBL-producing 

Klebsiellae from different perinatal intensive 

care units (PICUs) in Hungary 

I.B. Damjanova, Á. Tóth, J. Pászti, M. Jakab 


P1364 Adhesion to and invasion of human epithelial 

cells by ESBL and non-ESBL-producing 

Klebsiella pneumoniae strains 

H. Sahly, R. Podschun, S. Schutt, U. Ullmann 

(Kiel, D) 

P1365 Isolation of multi-resistant strains of 

Klebsiella oxytoca from neonatal intensive 

care unit – colonisation or infection? 

J. Jursa, A. Kordek, S. Giedrys-Kalemba 

(Szczecin, PL) 

P1366 Antimicrobial resistance of Gram-negative 

bacilli isolated from patients with 

bloodstream infections in ICUs 

A. Yuce, M. Erdenizmenli, N. Yapar, S. Senger 

(Izmir, TR) 

P1367 Risk factors for ICU-acquired imipenemresistant 

Gram-negative bacterial infections 

E. Akinci, A. Çolpan, H. Bodur, N. Balaban, 

A. Erbay (Ankara, TR) 

P1368 Epidemiology of integron-associated 

resistance in 2 ICUs during a non-outbreak 

period 

S. Nijssen, A. Florijn, M. Bonten, A. Fluit 

(Utrecht, NL) 

P1369 Intravenous (IV) colistin for the treatment 

of multiresistant Gram-negative bacilli: 

review of experience in 30 patients 

F. Kidd, S. Arias-Lopez, D. Socivica, B. Byl, 

M.J. Struelens, J.-L. Vincent, F. Jacobs 

(Brussels, B) 

P1370 The frequency of multidrug-resistant bacteria 

from clinical samples 

A. Dedeic Ljubovic, M. Hukic, M. Hadjijamakovic, 

A. Zvizdic, M. Sisirak (Sarajevo, BIH) 

P1371 Occurrence of extended-spectrum betalactamase-producing 

Escherichia coli strains 

in a university hospital 

V. Popova, M. Sredkova, H. Hitkova, E. Kanjovska 

(Pleven, BG) 

P1372 Serratia marcescens in clinical specimens 

over three years 

L. Naumiuk, E. Dziemaszkiewicz, A. Samet 

(Gdansk, PL) 

P1373 Genotyping of S. marcescens and 

K. pneumoniae nosocomial isolates from 

newborns 

G. Fabio, M. Pecorari, L. Piccinini, C. Venturelli, 

D. Barbarini, M.G. Tamassia, W. Gennari, 

A.T. Sabbatini, P. Marchegiano, F. Ferrari, 

S. Cattani, F. Rumpianesi, C. Casolari 

(Modena, Pavia, I) 


page 117

13:00–14:00 

Surveillance studies 


P1374 Prevalence and risk factors for nosocomial 

infections in 19 hospitals of Veneto Region 

(Italy) 

G. Pellizzer, L. Timillero, P. Mantoan, B. Allegranzi, 

M. Saia, P. Benedetti, E. Pegoraro, P. Spolaore 

(Vicenza, Castelfranco Veneto, Verona, Padua, I) 

P1375 Tn21-like elements disseminating carbapenemase 

genes in Italy: report from the SENTRY 

antimicrobial surveillance programme 

M. Toleman, R. Mendes, M. Castanheira, 

D. Bennett, R. Jones, T. Walsh (Bristol, UK) 

P1376 Clinical efficacy of cefepime in hospitalised 

patients with severe nosocomial infections. 

Results of a German surveillance study 

F. Vogel, K. Bodmann (Hofheim, Hildesheim, D) 

P1377 Evolution of nosocomial infections rates 

during five years in a university hospital 

M.F. Geyik, S. Hosoglu, C. Ayaz, O.F. Kokoglu, 

S. Akalin, M.K. Celen (Diyarbakir, TR) 

P1378 Nosocomial infection in Italy: results from the 

1st point prevalence for the INF-NOS ‘02–‘04 

surveillance 

G. Ippolito, G. Gesu, L. Giuliani, M. Larosa, 

G. Privitera – the INF-NOS study group 

P1379 Surveillance of bloodstream infections in 

Czech hospitals: epidemiological background 

of CZ-EARSS 

V. Jindrak, T. Bergerova, E. Bebrova, E. Stastna, 

E. Simeckova, P. Urbaskova 

(Prague, Pilsen, Kladno, Prerov, Strakonice, CZ) 

P1380 Bloodstream infection: comparing the 

epidemiology of the late 80's to that of the 

late 90's at a community hospital in Brazil 

M.B. Souza Dias, V.L. Borrasca, E.M. Psaltkids, 

D. Zanetta, G.M. Böhm 

(São Paulo, S. Jose Rio Preto, BR) 

P1381 Nosocomial infections: two prevalence 

studies (2000 – 2003) 

S. Kastanakis, S. Doukakis, M. Papadakis, 

L. Tzimis, P. Hatzilias, E. Tsafaraki, E. Volanis, 

E. Papadomanolaki, G. Alevraki, A. Tsouri, 

I. Varthalitis (Chania, GR) 

P1382 Five prevalence surveys of hospital-acquired 

infections in a Greek hospital 

S. Kastanakis, S. Doukakis, M. Papadakis, 

P. Hatzilias, E. Tsafaraki, L. Tzimis, E. Volanis, 

E. Papadomanolaki, G. Alevraki, A. Tsouri, 

I. Varthalitis (Chania, GR) 


P1383 Multi point prevalence investigation of 

nosocomial infections in a Greek tertiary 

hospital 

M. Vasiliadis, E. Maltezos, E. Archontidou, 

P. Peichamberis, D. Glaros, S. Kartali-Ktenidou 

(Alexandroupolis, GR) 

P1384 Prevalance of nosocomial infections in Ilam's 

hospitals, Iran 

N. Sadeghifard, F. Azizi Jalilian, J. Zaeimi Yazdi 

(Tehran, IR) 

P1385 Surveillance for nosocomial infections using 

special monitoring protocol in Austrian ICU 

A. Reiter, H. Hetz, P. Faybik, K. Krenn, H. Steltzer 

(Vienna, A) 

P1386 Calculation of incidence and repartition of 


F. Tissot Guerraz, N. Fayolle, R. Sibelle, O. Claris 

(Lyon, F) 

P1387 A computerised system of administrative 

data for nosocomial infection monitoring 

M. Saia, L. Timillero, P. Mantoan, B. Allegranzi, 

G. Pellizzer, P. Spolaore (Padua, Castelfranco 

Veneto, Vicenza, Verona, I) 

P1388 Cumulative microbiological laboratory data: 

an important tool for management of health 

care quality in the hospital 

I. Wybo, D. Piérard, A. Naessens, 

A. Van Zeebroeck, R. Van De Velde, 

S. Lauwers (Brussels, B) 

P1389 AMBU-KISS: quality control in ambulatory 

surgery 

D. Mlangeni, R. Babikir, M. Dettenkofer, 

P. Gastmeier, F. Daschner (Freiburg, Hannover, D) 

P1390 Investigation of the antibiotic susceptibility 

patterns of pathogens causing nosocomial 

infections using the E-test 

A. Yaman, Y. Tasova, F. Kibar, A.S. Inal, 

N. Saltoglu, O. Buyukcelik, B. Kurtaran, 

I.H. Dündar (Adana, TR) 

P1391 A 6-year study of risk factors, aetiology and 

outcome of late-onset septicaemia in 

premature neonates treated in a NICU 

M. Wasek, J. Behrendt, J. Karpe, 

U. Godula-Stuglik (Zabrze, PL) 

P1392 Antimicrobial resistance patterns of bacteria 

isolated from intensive care unit infections 

A. Bayram, I. Balci (Gaziantep, TR)


P1393 Isolation frequency and antibiotic resistance 

of bacteria recovered in a respiratory ICU in 

the years 1997 and 2003 

S. Karabela, S. Kanavaki, H. Moraitou, 

M. Makarona, G. Dimopoulos, M. Daganou, 

S. Triantaphyllou, P. Koumentakis, A. Rasidakis 

(Athens, GR) 

P1394 Incidence of surgical site infections in Italian 

surgical settings 

N. Petrosillo, M.L. Moro, E. Nicastri, L. Martini 

and the Italian Group for the Study of Surgical 

Site Infections 

P1395 Incidence of nocomial infection in Italian 

surgical wards 

M. Fiorio, F. Vigano, M. Larosa, A. Marvaso – 

the KIR-NOS Study Group 

P1396 Surgical site infection after cholecystectomy 

(laparoscopic vs open cholecystectomy) 

M. De Frutos Serna, T. Delgado, A. Melian, 

B. Castro, M.J. Ramos, A. Sierra (La Laguna, E) 

P1397 Surveillance of the infection in valvular 

replacement in cardiac surgery: 

an evaluation over 4 years 

M. De Frutos Serna, T. Delgado Melián, 

C. Menéndez, A. Torres Lana, M. Miguel Gómez, 

A. Sierra Lopez (La Laguna, E) 

P1398 Evaluation of post-operative nosocomial 

infections in a university faculty of medicine 

department of general surgery, Izmir 

M. Isikgoz Tasbakan, B. Arda, T. Yamazhan, 

H. Pullukcu, S. Ulusoy (Izmir, TR) 

P1399 Evaluation of surgical site infection rates by 

surveillance after hip arthroplasty 

F. Huenger, A. Schmachtenberg, D. Zolldann, 

H. Haefner, K. Nowicki, D.C. Wirtz, K. Bläsius, 

S.W. Lemmen (Aachen, Stolberg, D) 

P1400 Bacteraemia in patients with haematological 

malignancies 

D. Mylona-Petropoulou, G. Ganteris, 

H. Vagiakou-Voudris, G. Zorbas, H. Malamou-Lada 

(Athens, GR) 


page 119

Poster Sessions Tuesday, May 4, 2004 

12:00–13:00 

Infectious diseases and public health issues 

P1401 Surveillance study of incidence of HIVpositive 

patients in a low-risk group of 

community-acquired pulmonary tuberculosis 

M. Singh (Jaipur, IND) 

P1402 Epidemiological investigation of tuberculosis 

in Western Greece and the examination of the 

completness of notifications 

E. Jelastopulu, G. Tsiros, T. Constantinidis 

(Rio Patras, Alexandroupolis, GR) 

P1403 Survey of brucellosis seroprevalence in risk 

groups in Erzurum, Turkey 

A. Ayyildiz, H. Uslu, A.E. Aktas, H. Yazgi 

(Erzurum, TR) 

P1404 Epidemiological and economic effects of the 

proposed recommendation for universal 

varicella vaccination in Germany 

P. Wutzler, S. Wagenpfeil, T. Hammerschmidt, 

H. Bisanz, K. Banz, A. Neiss 

(Jena, Munich, D; Basle, CH) 

P1405 Infectious diseases imported to the Czech 

Republic between 1998 and 2002 

J. Kostalova, C. Benes, J. Kyncl, J. Castkova, 

B. Kriz (Prague, CZ) 

P1406 Harmonising the Acute Respiratory Infection 

Reporting System in the Czech Republic with 

the European Community Networks 

J. Kyncl, B. Prochazka, C. Benes, M. Havlickova, 

M. Otavova, J. Kostalova, B. Kriz (Prague, CZ) 

P1407 A prospective search for pertussis in Korean 

adults 

W.B. Park, S.W. Park, H.C. Jang, K.D. Lee, 

H.B. Kim, M.D. Oh, E.C. Kim, K.W. Choe 

(Seoul, Cheonan, KOR) 

P1408 Seroprevalence survey of Rickettsia typhi, 

Rickettsia conorii, and Bar29 strain in the 

South of Spain 

M. Bernabeu-Wittel, M.D. Del Toro, N. Cardeñosa, 

M.M. Nogueras, M.J. Rodríguez-Hernández, 

F. Vaquero, F. Márquez, M.A. Muniain, F. Segura, 

J. Pachón (Seville, Barcelona, Jaén, E) 

P1409 Dynamics of nasopharyngeal colonisation by 

Haemophilus influenzae in infants and young 

children 

A. Sulikowska, A. Mrówka, W. Hryniewicz 

(Warsaw, PL) 


P1410 Cell-detaching Escherichia coli activity in 

urinary tract infection isolates 

S. Gavilanes, S. Martinez, E. Chavez, A. Navarro, 

E. Drago, L. Leon, A. Manjarrez 

(Mexico City, MEX) 

P1411 Long-term surveillance of invasive group 

A streptococcal disease in the Netherlands, 

1994-2003 

B. Vlaminckx, W. van Pelt, L. Schouls, 

A. van Silfhout, E. Mascini, T. Fernades, 

A. Bosman, J.F.P. Schellekens 

(Utrecht, Bilthoven, NL) 

P1412 Early and late onset group B streptococcus 

disease at a central hospital, Harare, 

Zimbabwe 

S.R. Moyo, J. Lucas (Harare, ZW) 

P1413 Emergence of MRSA strains containing the 

Panton-Valentine leukocidin gene in the 

Netherlands 

W.J.B. Wannet, E. Spalburg, M.E.O.C. Heck, 

G.N. Pluister, R.J.L. Willems, A.J. de Neeling, 

J. Etienne (Bilthoven, Utrecht, NL; Lyon, F) 

P1414 Prevalence of group B streptococcal 

colonisation in Greek pregnant women 

S. Maraki, M. Dialynas, E. Nioti, T. Gavrilidi, 


P1415 Seroprevalence of rubella, cytomegalovirus 

and Toxoplasma gondii among women of 

reproductive age in the region of Thrace- 

Greece 

S. Mela, C. Tsigalou, T. Gkioka, E. Chrysafidou, 

G. Kampouromiti (Alexandroupolis, GR) 

P1416 Bacterial evaluation of supermarket bought 

chickens in the Mafikeng area (R.S.A) 

C.N. Ateba, D.T. Kawadza (Mmabatho, ZA) 

P1417 Prognostic factors in adult tetanus 

N. Saltoglu, Y. Tasova, D. Midikli, A.S. Inal, 

R. Burgut, I.H. Dündar (Adana, TR) 

P1418 Quality of life after tick-borne encephalitis 

V. Chmelik, P. Petr, I. Slamova, P. Filipova, 

L. Houserova, A. Chrdle, H. Kalova 

(Ceske Budejovice, CZ) 

P1419 The effect of short-time microwave exposures 

on Escherichia coli O157:H7 inoculated into 

hamburgers 

I. Apostolou, C. Papadopoulou, C. Dontorou, 

C. Salamoura, K. Ioannides, S. Leveidiotou 

(Ioannina, GR)


P1420 A retrospective evaluation of Listeria 

infections in Bari, South Italy, from March 

2002 to April 2003 

C. Rizzo, M.F. Coscia, G. Ceci, G. De Pascale, 

R. Monno, D. De Vito, G. Rizzo (Bari, I) 

P1421 Microbiologic survey of long-term-care 

facilities in Greece 

V. Grammelis, K. Kanellakopoulou, A. Kapaskelis, 

M. Gika, F. Baziaka, D. Katsala, H. Giamarellou, 

M.K. Lazanas (Athens, GR) 

P1422 Pseudo-contamination of blood components 

with Burkholderia cepacia during quality 

controls 

W. Ebner, E. Meyer, C. Schulz-Huotari, G. Zilow, 

M. Dettenkofer, U. Frank (Freiburg, D) 

P1423 The proteolitic and lipolitic activity of 

Pseudomonas strains isolated from raw milk 

G. Uraz, B. Dadakoglu, D. Etöz (Ankara, TR) 

P1424 Endocarditis due to Enterococcus faecalis: 

risk factors and outcome in 21 cases from 

a five-year national survey 

M. Noskovicova, V. Hricak, V. Krcmery 


P1425 Knowledge, attitudes and practices of 

sexually transmitted infections in immigrant 

female sex workers 

A. Mari, A. Matteelli, M. Guana, S. Capone, 

C. Pizzocolo, N. Saleri, M. Manfrin, U. Bianchi, 

F. Castelli (Brescia, I) 

P1426 Bacillus cereus in orthopaedic and trauma - 

t ology wards. An unrecognised pathogen? 

A 63-case study 

E. Bonnet, M. Alvarez, M. Archambaud, 

H. Bensafi, A. Dubouix, C. Cauhepe, 

B. Chaminade, P. Bonnevialle, N. Marty, 

H. Dabernat, B. Marchou, P. Massip (Toulouse, F) 

P1427 Determination of the quantity of aflatoxin M1 

in pasteurised milk in Shiraz 

S. Alborzi, B. Pourabbas (Shiraz, IR) 

P1428 Fungal contamination in a cheese factory 

in Iran 

S. Alborzi, A. Karbasi (Shiraz, IR) 

P1429 An investigation of infection risks of patients 

newly fitted with orthokeratology contact 

lenses 

M.V. Boost, P. Cho, V. Chui (Hong Kong, HK) 

P1430 Evaluation of Bartels ELISA Legionella urinary 

antigen in water samples 

S. Blanco, J. Domínguez, C. Prat, R. Rivelo, 

M. Pérez, M. Campanyà, V. Ausina (Badalona, E) 

12:00–13:00 

Infection in the immunocompromised 

HIV-negative host 

P1431 Fusobacterium nucleatum bacteraemia in 

paediatric hematology patients 1997–2003 

F. Bosma, P.D. Sturm, T. Schülin (Nijmegen, NL) 

P1432 Bacteriological findings in children with 

haematological disorders 

B. Kowalska-Krochmal, I. Dolna, I. Choroszy-Król, 

J. Ruczkowska, R. Franiczek (Wroclaw, PL) 

P1433 Surveillance of nosocomial sepsis and 

pneumonia in patients with bone marrow 

transplantation or peripheral blood stem-cell 

transplantation. A Multicentre project 

M. Dettenkofer, R. Babikir, S. Wenzler, E. Meyer, 

H. Rüden, F. Daschner (Freiburg, Berlin, D) 

P1434 Nocardiosis trends in a teaching hospital: 

a 15-year study 

R. Matulionyte, P. Rohner, I. Uckay, D. Lew, 

K. Bouchuigui-Waf, J. Garbino (Geneva, CH) 

P1435 Reactivation salmonellosis in cancer patients 

after antineoplasic chemotherapy 

J. Delaloye, G.M. Merlani, P.E. Tarr (Lausanne, CH) 

P1436 Pulmonary infiltrates in solid organ transplant 

recipients. Mortality risk factors 

C. Cervera, G. Soto, N. De Benito, P. Rivas, 

F. Cofan, A. Rimola, E. Roig, T. Pumarola, 

A. Torres, A. Moreno (Barcelona, E) 

P1437 Prevalence of BK virus infection in solid organ 


M. Fogueda, P. Muñoz, C. Rodriguez, 

M.J. Dominguez, R. Bañares, J. Palomo, 

E. Verde, E. Bouza (Madrid, E) 

P1438 A retrospective study on Pneumocystis 

carinii pneumonia in critically ill patients 

D. Peres Bota, R. Rodriguez Villalobos, 

J.-L. Vincent (Brussels, B) 

P1439 Detection of Pneumocystis carinii by 

polymerase chain reaction in bronchoalveolar 

lavage specimens: clinical significance and 

correlation with other diagnostic methods 

E. Nieminen, K. Rantakokko-Jalava, O. Meurman, 

J. Nikoskelainen, J.H. Salonen (Turku, FIN) 

P1440 Bacterial infection in cirrhotic patients with 

variceal bleeding 

J. Jurankova, J. Lata, M. Senkyrik, L. Husova 

(Brno, CZ) 


page 121


P1441 Diabetic foot infections: risk factors and 

microbiological spectrum 

M. Kompoti, S. Drimis, M. Bitza, L. Thiaspras, 

A. Melidonis, D. Gianneli, C. Nikolopoulou, 

S. Heraklianou (Athens, GR) 

P1442 Actinomyces neuii isolation from foot 

necrotic ulcer in an immunocompromised 

patient 

K. Papaefstathiou, M. Sonikian, M. Zoumberi, 

D. Arvanitis, D. Vlassopoulos, G. Kouppari 

(Athens, GR) 

P1443 Serum and peripheral blood mononuclear 

cells infectious burden: correlation to 

inflammation and atherosclerosis in 

hemodialysis patients 

G. Tsirpanlis, S. Chatzipanagiotou, A. Ioannidis, 

F. Boufidou, S. Moutafis, A. Lagouranis, P. Tseke, 

C. Nicolaou (Athens, GR) 

P1444 Human herpesvirus 8 infection in 

haematopoietic stem cells transplant 

recipients 

K. Roubalová, A. Vítek, J. Sajdová, A. Suchánková 

(Prague, CZ) 

P1445 Acquired Shapiros syndrome (recurrent 

hypothermia) due to human herpesvirus 

6 after stem cell transplantation 

L. Arenillas, F. Graus, A. Smithson, R. Palmero, 

M. Rovira (Barcelona, E) 

P1446 Ganciclovir-resistant cytomegalovirus 

infection in a heart transplant recipient 

J. Garcia-Martinez, L. Folgueira, R. Delgado, 

S. Hernando, C. Prieto, J. Aguado, J. Otero 

(Madrid, E) 

P1447 Prevention of iatrogenic Creutzfeldt-Jakob 

disease in recipients of corneal transplants: 

genetic testing of donors 

E. Mitrova, G. Belay, D. Slivarichova, 

V. Verchovodkova, V. Jovankovicova 


P1448 Putative role of SV40 in BMT children 

M. Comar, P. D'Agaro, M. Andolina, 

N. Maximova, B. Gregoretti, G. Dal Molin, 

M. Tognon, C. Campello (Trieste, I) 

P1449 Contribution to the studies of the role of 

Chlamydiae and human herpesvirus 6 (HHV6) 

in pathogenesis of multiple sclerosis 

N. Sojkova, V. Frankova, E. Havrdova, 

K. Mlcochova (Prague, CZ) 


P1450 Retrospective analysis of cancer patients with 

neutropenic fever and predictors of treatment 

success 

G. Sain Güven, B. Cakir, Y. Cetinkaya Sardan, 

P. Zarakolu, O. Uzun, S. Unal, M. Akova 

(Ankara, TR) 

P1451 High-dose levofloxacin for the treatment of 

febrile neutropenia 

J. Kahn, N. Davis (Raritan, USA) 

P1452 Empiric antibiotic treatment of adults with 

neutropenic fever in a general internal 

medicine ward 

R. Shichmanter, E. Miller, M. Shtalrid, Z. Landau 

(Rehovot, IL) 

P1453 Aspergillus: air quality monitoring in areas 

reserved for the treatment of immuno - 

depressed patients 

G. Finzi, P. Cacciari, N. Manoni, N. Alvaro, 

L. Mavilla (Bologna, I) 

P1454 Control but not eradication of Legionella 

pneumophila sg1 in a teaching hospital 

A. Bilén, B. Eriksson, G. Tufveson, A. Johansson, 

J. Evebjörk, S. Bernander, U. Ransjö 

(Uppsala, Stockholm, S) 

12:00–13:00 

Antimicrobial resistance mechanisms – II 

P1455 Clindamycin resistance among Streptococcus 

agalactiae isolates and genotypes 

M. Agreda, F. El Knaichi, E. Martin, J. Picazo 

(Madrid, E) 

P1456 Spread of the new sul3 gene in human and 

animal E. coli in Sweden 

M. Grape, C. Greko, G. Kronvall 

(Stockholm, Uppsala, S) 

P1457 Characterisation of a novel AAC (3) I enzyme 

found in a class 1 integron from a Salmonella 

enterica isolate causing traveller’s diarrhoea 

R. Cabrera, J. Ruiz, P. Goñi, R. Gómez-Lus, 

M. Jiménez de Anta, J. Gascón, J. Vila 

(Barcelona, Zaragoza, E) 

P1458 ParE mutations in Pseudomonas aeruginosa 

clinical isolates with a high level of 

ciprofloxacin resistance 

S. Rejiba, A. Aubry, V. Jarlier, E. Cambau 

(Tunis, TN; Paris, F)


P1459 Contribution of outer membrane protein 

alterations and beta-lactamases in 

carbapenem-resistant Acinetobacter spp. 

M. Castanheira, J. Smayevski, R.N. Jones, 

T.R. Walsh (Bristol, UK; Buenos Aires, AR; 

North Liberty, USA) 

P1460 Post-genomic identification of a new 

subclasss B3 metallo-beta-lactamase (NOV-1) 

from Novosphingobium aromaticivorans 

J.D. Docquier, M. Stoczko, G. Amicosante, 

J.M. Frère, G.M. Rossolini 

(Liège, B; Siena, L’Aquila, I) 

P1461 New aminoglycoside and chloramphenicol 

acetyltransferase-encoding gene cassettes in 

class 1 integrons from multiresistant 

Pseudomonas aeruginosa clinical isolates 

J.D. Docquier, C. Mugnaioli, F. Luzzaro, 

R.A. Musmanno, G.M. Rossolini 

(Liège, B; Siena, Varese, I) 

P1462 Hyperproduction of AmpC beta-lactamase in 

a clinical isolate of Escherichia coli associated 

with a 30-base pair deletion in the attenuat 

or region of ampC 

F. Fernández-Cuenca, A. Pascual, L. Martínez- 

Martínez (Seville, E) 

P1463 In vivo selection of Enterobacter aerogenes 

with reduced susceptibility to cefepime 

associated with either decreased expression 

of an outer membrane protein of 40 kDa or 

hyperproduction of AmpC beta-lactamase 

F. Fernández-Cuenca, A. Pascual, J.-M. Rodríguez- 

Martínez, L. Martínez-Martínez (Seville, E) 

P1464 Analysis of the mutations in the pbp genes of 

penicillin-nonsusceptible pneumococci from 

Turkey 

M. Bicmen, Z. Gulay (Izmir, TR) 

P1465 Mutations in erm(B) associated with rare, 

low-level telithromycin resistance in 

Streptococcus pneumoniae: 

3-year data from PROTEKT 

D. Farrell, I. Morrissey, S. Bakker, D. Felmingham 

(London, UK) 

P1466 Fitness costs of apramycin resistance 

plasmids conferring cross-resistance to 

gentamicin and tobramycin 

C.M. Yates, D.J. Shaw, M.E.J. Woolhouse, 

S.G.B. Amyes (Edinburgh, UK) 

P1467 High-level aminoglycoside resistance of 

Streptococcus bovis isolates in a teaching 

hospital in Hong Kong – studies on prevalence 

and resistance mechanisms 

V.C.Y. Chow, R.C.Y. Chan, M.-L. Chin, 

A.F.B. Cheng (Hong Kong, HK) 

P1468 Molecular characterisation of a new variant 

of IND-type metallo ß-lactamase expressed in 

a clinical isolate of CDC group Gram-negative 

asaccharolytic rod 

B. Caporale, M. Perilli, M.L. Mezzatesta, 

S. Stefani, G. Celenza, F. De Santis, M. Fiore, 

G.M. Rossolini, G. Amicosante 

(L'Aquila, Catania, Siena, I) 

P1469 Characterisation of beta-lactam resistance 

among clinical Escherichia coli strains in 

Portugal 

M. Ferreira, E. Ferreira, M. Caniça, GEMVSA 

(Lisbon, P) 

P1470 Molecular basis of fusidic acid resistance in 

Staphylococcus aureus from patients with 

atopic dermatitis undergoing therapy with 

fusidic acid 

A.J. O'Neill, A.R. Larsen, A.S. Henriksen, 

I. Chopra (Leeds, UK; Copenhagen, DK) 

P1471 High frequency of association between 

CTX-M-beta-lactamase-coding genes and 

the ISEcp1 insertion element 

M. Pimkin, I. Palagin, M. Stepanova, M. Edelstein 


P1472 Fluconazole resistance mechanisms in 

C. krusei clinical isolates. 

The contribution of efflux pumps 

J. Guinea, M. Sánchez-Somolinos, T. Pelaez, 

O. Cuevas, J. Martínez-Alarcón, L. Alcalá, 

P. Muñoz, E. Bouza (Madrid, E) 

P1473 Characterisation of the Ambler class B 

chromosome-encoded ß-lactamases SLB-1 

and SFB-1 from Shewanella livingstonensis 

and Shewanella frigidimarina 

L. Poirel, C. Heritier, P. Nordmann 

(Le Kremlin Bicetre, F) 

P1474 Evidence for an efflux pump affecting 

carbapenem susceptibility in Bacteroides 

fragilis 

K. Aldridge, K. Lolans, P. Schreckenberger, 

J.P. Quinn (New Orleans, Chicago, USA) 


page 123


P1475 Macrolide resistance and its genetic 

mechanism in Streptococcus pneumoniae in 

Finland 2002, with special reference to 

telithromycin resistance 

M. Rantala, P. Huovinen, J. Jalava 

and The Finnish Study Group for Antimicrobial 

Resistance 

P1476 Antibiotic and biocide resistance mechanisms 

in Escherichia coli O157 

M. Braoudaki, A. Hilton (Birmingham, UK) 

P1477 A novel SHV-derived extended-spectrum 

beta-lactamase (SHV-52) that hydrolyses 

ceftazidime through a single-amino-acid 

substitution (L169R) 

L. Ma, J. Alba, S. Kimura, Y. Ishii, M. Ishiguro, 

L.K. Siu (Taipei, TW; Tokyo, Osaka, JP) 

12:00–13:00 

Mycobacterial diagnosis 

P1478 Evaluation of an RAPID bioactive 

amplification with probing Mycobacterium 

tuberculosis (RAPID BAP-MTB) assay for 

identification of M. tuberculosis in respiratory 

specimens 

S.K. Wang, C.Y. Huang, P.R. Hsueh 

(Taipei, Tainan, TW) 

P1479 Early laboratory diagnosis of pulmonar 

tuberculosis. How to evaluate the results? 

J. Lago, E. Alvares, H. Pinto, A. Remédios, 

A. Silva Graça (Lisbon, P) 

P1480 Rapid cultivation and improved detection 

of Mycobacterium tuberculosis and other 

mycobacterial species by use of culture 

supplements 

I. Szpinda, I. Olsen, T. Tonjum (Oslo, N) 

P1481 Identification of clinical nontuberculous 

mycobacteria isolates by using polymerase 

chain reaction-restriction enzyme analysis in 

a teaching hospital 

O. Bedir, A. Albay, O. Kisa, O. Baylan, L. Doganci 

(Ankara, TR) 

P1482 Tuberculosis of the parotid gland. Diagnosis 

by polymerase chain reaction 

T. Kontopoulou, P. Fanourgiakis, M. Samarkos, 

D. Loverdos, C. Peppas, D. Rontogianni, 

E. Vaidakis (Athens, GR) 

P1483 Polymerase chain reaction based detection of 

Mycobacterium tuberculosis complex in lupus 

vulgaris: a case report 

O. Baylan, E. Arca, A. Ozcan, O. Kisa, A. Albay, 



P1484 Failure to detect the IS6110 repetitive DNA 

element of Mycobacterium tuberculosis in 

exhaled breath condensate of patients with 

active pulmonary tuberculosis 

R. Jain, C. Schriever, L Danziger, S. Franzblau, 

S. Cho, R. Glowacki, S. Welbel, I. Rubinstein 

(Chicago, USA) 

P1485 Is it necessary to incubate for eight weeks 

specimens submitted to the mycobacteriology 

laboratory? 

M.J. Ruiz-Serrano, O. Cuevas, L. Alcalá, 

N. García-Escribano, O. Pérez-Olaso, M. Marín, 

D. García-Viedma, E. Bouza (Madrid, E) 

P1486 A new molecular method for the 

identification of mycobacteria in clinical 

samples 

M. Sánchez-Somolinos, M. Ruiz-Serrano, 

E. Rodriguez, M. Marín-Arriaza, D. García de 

Viedma, E. Bouza (Madrid, Guadalajara, E) 

P1487 Fast and sensitive detection of the 

Mycobacterium tuberculosis complex by 

real-time PCR 

S.O. Cramer, F. Matinmehr, D. Hillemann 

(Hamburg, Borstel, D) 

P1488 Five-year experience with Roche Amplicor 

PCR asay for Mycobacterium tuberculosis 

I. Gros, J.-M. Naccache, P. Blondel, 

S. Desligneres, F. Lhote, D. Mechali, 

C. Chaplain (Saint Denis, F) 

P1489 Comparison of the MB/BacT culture system 

and the Lowenstein-Jensen medium for 

detection of mycobacteria from respiratory 

samples 

J. Lago, A. Remédios, A. Silva Graça (Lisbon, P) 

P1490 Comparison of the performance of different 

assays for the immune-diagnosis of 

tuberculosis based on ESAT-6 and CFP10 

selected peptides 

D. Vincenti, S. Carrara, R. Casetti, V. Di Virgilio, 

M. Amicosante, F. Poccia, E. Girardi, D. Goletti 

(Rome, I) 

P1491 Evaluation of the BDProbeTec ET system 

for direct detection of Mycobacterium 

tuberculosis complex in respiratory and 

extra-respiratory specimens 

M. Lecuona, M.A. Miguel, M. Cuervo, 

M.J. Ramos, B. Castro, O. Diez, A. Sierra 

(Sta Cruz de Tenerife, E)


P1492 Evaluation of timing, number and yield 

of blood cultures in the detection of 

Mycobacterium tuberculosis bacteraemia 

in HIV-infected patients in Portugal 

T. Hanscheid, J. Melo-Cristino, C. Monteiro, 

L. Marques-Lito, M. Salgado (Lisbon, P) 

P1493 16S rRNA PCR for retrospective detection 

of Mycobacterium spp in formalin-fixed 

paraffin-embedded archival specimens 

B. Mulder, H. Wilke, F. Sutorius, R. Hendrix 


P1494 Identification of mycobacteria with 16S 

ribosomal RNA gene sequence analysis 

B. Mulder, E. Oude Nijhuis, H. Wilke, R. Hendrix 


P1495 The role of tuberculosis skin test conversion 

in detection of tuberculosis 

O. Ergonul, R. Keskiner, B. Dokuzoguz 

(Ankara, TR) 

12:00–13:00 

Mycobacterial infection: epidemiology 

P1496 Mycobacterium kansasii infection in Spain: 

results from an epidemiologic national 

survey (2000-2003) 

F. Alcaide, L. Calatayud, M. Santín, J. Dorca, 

G. Rufí, R. Martín and the Mycobacterium 

kansasii Spanish Working Group (GEMKA) 

P1497 A case of disseminated tuberculosis 

presenting as Crohn’s disease 

O. Tabak, I. Yurdakul, A. Dobrucali, H. Uzunismail, 

S. Demirci, C. Akman, S. Erdamar (Istanbul, TR) 

P1498 Mycobacterial contamination of a transfusion 

unit: lessons for the routine screening of 

blood products 

H. Sprecher, S. Davidson, G. Rabino, I. Kassis, 

R. Finkelstein, I. Oren (Haifa, IL) 

P1499 Tuberculous meningitis in northern Greece 

F. Kamaria, S. Zisopoulou, A. Papalexandri, 

D. Kolokotroni, A. Kansouzidou 

(Thessalonica, GR) 

P1500 Isolation frequency of Mycobacterium sp. in 

extrapulmonary clinical sources 

S. Nikolaou, S. Kanavaki, A. Skroubellou, 

P. Papageorgiou, S. Karambela, E. Varonou, 

A. Papavasileiou, F. Kontos, V. Tamvakis 

(Athens, GR) 

P1501 Simultaneous occurrence of tuberculosis and 

non-Hodgkin’s lymphoma within cervical 

lymph nodes 

P. Fanourgiakis, I.I. Androulakis, A. Georgala, 

M. Vekemans, G. Andry, E. Vaidakis, M. Aoun 

(Athens, GR; Brussels, B) 

P1502 TB and HIV rates in Odessa, Ukraine: 

a dramatic rise in the last decade 

F. Drobniewski, V. Nikolayevskyy, Y. Bazhora, 

A. Asmolov, Y. Balabanova, S. Servetsky 

(London, UK; Odessa, UKR) 

P1503 IS6110 RFLP analysis of Mycobacterium 

tuberculosis strains in the Free State 

province, South Africa 

A. van der Spoel van Dijk, 

M.N. Janse van Rensburg (Bloemfontein, ZA) 

P1504 Infections due to non-pigmented rapidly 

growing mycobacteria (NPRGM) in a 


J. Esteban, F. Santos-O'Connor, J.I. Garcia-Cia, 

A. Ortiz, F. Soriano (Madrid, E) 

P1505 Osteoarticular infections due to mycobacteria 

in a university hospital 

J.I. Garcia-Cia, J. Esteban, A. Ortiz, F. Soriano 

(Madrid, E) 

P1506 Mycobacterium malmoense lymphadenitis in 

Spain: first two cases in immunocompetent 

patients 

A.I. López-Calleja, M.A. Lezcano, S. Samper, 

F. De Juan, M.J. Revillo (Zaragoza, E) 

P1507 Central nervous system tuberculosis: 

epidemiological, clinical features and 

outcome in 133 patients 

B. Kilani, L. Ammari, H. Tiouiri, F. Kanoun, 

C. Marrakchi, A. Goubontini, F. Zouiten, 

T. Ben Chaabane (Tunis, TN) 

P1508 Information system of bacillary tuberculosis – 

5 years transition 

V. Príkazsky‘, M. Havelková, V. Polanecky‘ 

(Prague, CZ) 

P1509 Evaluation of PPD conversions in prisoners 

in Bandarabbas, Iran 

P. Davoodian, J. Zerang, M. Darvishkhah 

(Bandarabbas, IR) 

P1510 Clinical manifestation of leprosy in a pregnant 

woman 

B. Boeddinghaus, C. Brandt, R. Enzensberger, 

V. Gies, R. Ludwig, S. Kramme, V. Brade 

(Frankfurt, Hamburg, D) 


page 125


P1511 Tuberculous spondylitis in Cukurova, Turkey 

Y. Tasova, T. Sarpel, S. Inal, N. Saltoglu, 

B. Kurtaran, A. Sanli (Adana, TR) 

P1512 Evaluation of mono- and multiresistance 

to primer antituberculous agents of 

Mycobacterium tuberculosis strains 

recovered from Greek and immigrant 

patients with newly diagnosed pulmonary 

tuberculosis 

S. Nikolaou, S. Kanavaki, P. Papageorgiou, 

A. Skroubellou, S. Karambela, F. Kontos, 

E. Varonou, V. Sgoutzos, V. Tamvakis 

(Athens, GR) 

12:00–13:00 

Nosocomial infections: II 

P1513 A European consensus on infection control 

professionals training 

B. Cookson on behalf of the HELICS Education 

Group 

P1514 The Academy for Infection Management: 

AIMing to improve outcomes in nosocomial 

infections 

J. Rello, M.H. Kollef, A. Shorr 

(Tarragona, E; St Louis, Washington, USA) 

P1515 Diversity of infection control policies 

and practices in European hospitals: 

report from the ARPAC project 

D. Wagner, M. Struelens, B. Cookson, A. Voss, 

F. MacKenzie, J. Bruce, I.M. Gould 

and the ARPAC Steering Committee 

P1516 Infection control policies for multiresistant 

“alert” organisms in European hospitals: 

report from the ARPAC project 

D. Wagner, M. Struelens, J. Bruce, F. MacKenzie, 

I.M. Gould, B. Cookson, P. van den Broek, A. Voss 

(Brussels, B; Aberdeen, London, UK; 

Leiden, Nijmegen, NL) 

P1517 Influence of prophylctic antibiotic regimen 

on resistance rates of Staphylococcus 

epidermidis in orthopaedic surgery 

B. Tiodorovic, M. Mitkovic (Nis, CS) 

P1518 New views on large bowel surgery 

chemoprophylaxis. Compared administration 

of one dose of ticarcilline / clavoulanic acid 

against two 

P. Ntasiou, K. Kanellakopoulou, S. Pinis, 

N. Galanakis, A. Dervisoglou, P. Giannakakis, 

H. Giamarellou (Pireus, Athens, GR) 


P1519 New aspects concerning chemoprophylaxis 

in elective cholecystectomy 

A. Dervisoglou, K. Kanellakopoulou, S. Pinis, 

N. Galanakis, S. Pierakakis, P. Giannakakis, 

P. Dasiou, C. Iordanou, S. Liveranou, 

H. Giamarellou (Pireus, Athens, GR) 

P1520 Ceftriaxone versus other antibiotics for 

surgical prophylaxis 

S. Esposito, S. Noviello, A. Vanasia, P. Venturino 

(Naples, I) 

P1521 Monitoring of antibacterial prophylaxis in 

general surgery: results from a muticentre 

Italian incidence study 

M. Fiorio, F. Vigano, A. Marvaso, M. Larosa – 

the KIR-NOS Study Group 

P1522 Prognosis of unknown origin bacteraemias 

in critically ill patients 

S. Sancho, R. Zaragoza, A. Artero, J.J. Camarena, 

R. González, J. Alberola, J.M. Nogueira 

(Valencia, E) 

P1523 Attributable mortality of nosocomial 

candidaemia caused by Candida albicans and 

Candida non-albicans species in critically ill 

patients 

S. Blot, J. De Waele, K. Vandewoude, 

D. De Bacquer, E. Hoste, J. De Schuijmer, 

J. Decruyenaere, F. Colardyn (Ghent, B) 

P1524 Predictors of nosocomial Acinetobacter 

baumannii bacteraemia in an intensive care 

unit 

R. Zaragoza, A. Artero, J.J. Camarena, S. Sancho, 

J. Navarro, R. González, J.M. Nogueira 

(Valencia, E) 

P1525 Antibiotics cycling in ICU: results of 1.5-year 

experience 

D. Protsenko, S. Yakovlev, B. Gelfand, 

Y. Romanovskiy, A. Yaroshetsky (Moscow, RUS) 

P1526 Evaluation of the risk factors for mortality and 

nosocomial infection in intensive care units 

A. Çolpan, E. Akinci, A. Erbay, N. Balaban, 

H. Bodur (Ankara, TR) 

P1527 Knowledge, attitude and behaviour of health 

care workers in two Indonesian teaching 

hospitals on the island of Java 

D.O. Duerink, D. Roeshadi, H. Wahyono, 

P.J. Van den Broek on behalf of the AMRIN 

study group, Indonesia and The Netherlands 

P1528 Assessment of the impact of the 

microbiological reports on the antibiotic 

treatment of bacteraemia 

A. Vasilakopoulou, I. Stefanou, A. Pantazatou, 

J. Papaparaskevas, A. Avlamis (Athens, GR)


P1529 Nosocomial infection prevention and control 

programme during hospital reconstruction 

M. Gurgui, J. Barrio, A. Cotura, M. Galvez, 

C. Roig, A. Coloma, M. Alvarez, P. Coll, 

G. Vazquez (Barcelona, E) 

P1530 Environmental organisms from different 

wards in a teaching hospital 

S. Dancer, M. Coyne, A. Thomson, A. Guleri, 

S.R. Alcock (Glasgow, UK) 

P1531 New way of microbe decontamination from 

air – MFI method 

Z. Muszyñski, I. Mirska (Poznan, PL) 

P1532 Disinfection of surfaces in hospital isolation 

rooms with ultraviolet C (UVC) light, 

compared with chloramine 

B.M. Andersen, H. Bånrud, E. Bøe, O. Bjordal, 

F. Drangsholt (Oslo, Rud, Trondheim, N) 

P1533 Controlling procedures for reprocessing 

flexible gastrointestinal endoscopes – 

the value of g-control charts 

T. Slotsbjerg, I. Petersen, H. Westh 

Copenhagen Clean-endoscope Group 

P1534 Preventing the spread of Legionella in 

hospital wards: measures adopted in a 

polyclinic, Bologna 

G. Finzi, P. Cacciari, N. Manoni, N. Alvaro, 

L. Mavilla (Bologna, I) 

P1535 Nosocomial Legionella infections confirmed 

by molecular typing 

L. Franzin, D. Cabodi, N. Bonfrate (Turin, I) 

P1536 Experience with a chlorine dioxyde water 

treatment system to control Legionella in 

a hospital hot water supply 

G. Mascart, M. Doyen, K. De Cuyper (Brussels, B) 

P1537 Sustained antimicrobial activity of a novel 

triclosan hand preparation 

T. Karpanen, T. Worthington, P. Lambert, T. Elliott 


P1538 Evaluation of bacteriological agents isolated 

from operating room staff after hand 

scrubbing in Yazd medical university hospitals 

J. Hossain-Zadeh, M. Golvardy, M. Mohseni, 

M. Khalili (Yazd, IR; Boston, USA) 

P1539 Evaluation of preventative methods in 

blood-borne pathogens among health care 

workers 

A. Tatsiopoulos, K. Mandraveli, M. Imprisimi, 

A. Politou, S. Alexiou-Daniel (Thessalonica, GR) 

12:00–13:00 

Ventilator-associated pneumonia 

P1540 Evaluation of patients with ventilatorassociated 

pneumonia 

A. Erbay, H. Bodur, E. Akinci, N. Balaban, 

A. Çolpan (Ankara, TR) 

P1541 Usefulness of serial quantitative cultures 

of bronchoalveolar lavage to control the 

development of antibiotic resistance in 

Pseudomonas aeruginosa causing ventilatorassociated 

pneumonia 

E. Tacconelli, M.A. Cataldo, F. Magnano, 

M.A. Pennisi, M. Antonelli, U. Frank, R. Cauda 

(Rome, I; Freiburg, D) 

P1542 Preliminary bronchoalveolar lavage culture 

results in ventilator-associated pneumonia 

E. Giantsou, N. Liratzopoulos, N. Boubopoulos, 

I. Kouyoumtzi, M. Panopoulou, S. Kartali, 

G.I. Minopoulos, K.I. Manolas 

(Alexandropolis, GR) 

P1543 Ventilator-associated pneumonia and 

modification of initially inappropriate anti - 

biotic therapy according to bronchoalveolar 

lavage culture results: timing and outcome 

E. Giantsou, G. Liberakidis, M. Papageorgiou, 

E. Alepopoulou, A. Grapsa, N. Liratzopoulos, 

G.I. Minopoulos, S. Kartali, K.I. Manolas 


P1544 Ventilation-associated pneumonia and 

de- escalation practice, oriented by the results 

of bronchoalveolar lavage vs transtracheal 

aspiration cultures 

E. Giantsou, K. Romanidis, N. Boubopoulos, 

G. Liberakidis, E. Alepopoulou, S. Kartali, 

G.I. Minopoulos, K.I. Manolas 


P1545 Pseudomonas aeruginosa and ventilatorassociated 

pneumonia: impact on outcome 

and duration of mechanical ventilation 

E. Giantsou, E. Efraimidou, I. Kouyoumtzi, 

M. Panopoulou, A. Grapsa, N. Liratzopoulos, 

G.I. Minopoulos, S. Kartali, K.I. Manolas 


P1546 Ventilator-associated pneumonia due to 

glycopeptide-intermediate S. aureus in 

intensive care unit patients: does vancomycin 

remain clinically effective? 

S. Trad, A. Ben Ali, M. Garrouste-Orgeas, 

J.C. Nguyen Van, J.F. Timsit, M.D. Kitzis, 

B. Misset, J. Carlet, F. Goldstein (Paris, F) 


page 127


P1547 Incidence, risk factors and mortality of 

nosocomial pneumonia in intensive care 

units: a prospective study 

E. Alp, M. Guven, O. Yildiz, B. Aygen, A. Voss, 

M. Doganay (Kayseri, TR; Nijmegen, NL) 

P1548 Three-year surveillance of ventilatoryassociated 

pneumonia in a paediatric 

intensive care unit 

A. Pawinska, W. Kaminska, M. Migdal, J. Patzer, 

D. Dzierzanowska (Warsaw, PL) 

P1549 Antimicrobial resistance of Gram-negative 

bacilli isolated from patients with ventilatorassociated 

pneumonia in a Turkish university 

hospital 

A. Yuce, N. Yapar, M. Erdenizmenli, S. Senger 

(Izmir, TR) 

P1550 Nosocomial pneumonia in post-surgical 

patients in the increased care unit 

P. Bakakos, D. Mallios, K. Tzagkaraki, G. Hillas, 

C. Moschos, S. Marinopoulos, A. Rasidakis 

(Athens, GR) 

P1551 The colonisation with polyresistant strains 

and bronchopulmonary infectious complications 

in multiple severe trauma patients 

V. Boiarintsev (St.-Petersburg, RUS) 

12:00–13:00 

Nosocomial infections: nonfermentative 

Gram-negative bacilli – II 

P1552 Changing epidemiology of multiresistant 

Acinetobacter baumannii in intensive care 

and burns unit patients, Sydney, Australia 

T. Gottlieb, R. Bradbury, E. Cheong 

(Concord, AUS) 

P1553 Antibiotic susceptibility of Acinetobacter 

strains isolated in blood cultures of children 

E. Çiftçi, E. Ayberkin, H. Güriz, A.D. Aysev, 

E. Ince, Ü. Dogru (Ankara, TR) 

P1554 Epidemiological characterisation of 

Acinetobacter baumanii isolated in a 


M.I. Ramos, T. Delgado, M. De Frutos Serna, 

M. Lecuona, M. Garcia Prados, A. Sierra 

(La Laguna, E) 

P1555 Acinetobacter baumanii isolated from surgical 

patients 

S. Baka, I. Logginidis, E. Chatzoudi, 

E. Gamaletsos, S. Demeridou, E. Choustoulakis, 

E. Kouskouni (Athens, GR) 


P1556 A. baumannii clonal dissemination in Brazilian 

intensive care units during 2002 

C. Mendes, J. Sampaio, S. Sinto, S. Leao, 

C. Oplustil, P. Turner, C. Kiffer – 

MYSTIC Brazil Group 

P1557 One hundred fifty Acinetobacter spp. isolates 

– identifications by API and VITEK systems 

A. Sledzinska, E. Czarniak, A. Samet, J. Kur 

(Gdansk, PL) 

P1558 Bacteraemia due to Stenotrophomonas 

maltophilia strains in children 

E. Ayberkin, E. Çiftçi, H. Güriz, A.D. Aysev, 

E. Ince, S. Arsan, G. Yavuz, Ü. Dogru (Ankara, TR) 

P1559 Typing of hospital strains of 

Stenotrophomonas maltophilia by pulsedfield 

gel electrophoresis 

W. Kaminska, J. Patzer, A. Pawinska, 

J. Wieczynska, D. Dzierzanowska (Warsaw, PL) 

P1560 The Stenotrophomonas maltophilia K279a 

genome sequence project 

M. Avison, A. Okazaki, V. Gould, J. Parkhill 

(Bristol, Cambridge, UK) 

P1561 Sub-grouping of Stenotrophomonas 

maltophilia isolates by 16S rRNA sequence 

allows prediction of beta-lactam resistance 

profile 

A. Okazaki, V. Gould, M. Avison (Bristol, UK) 

P1562 Expression of putative pathogenicity factors 

by clinical isolates of Stenotrophomonas 

maltophilia 

R. Podschun, H. Sahly, N. Vellmer, U. Ullmann 

(Kiel, D) 

P1563 Outbreak of Pseudomonas putida bloodstream 

infection 

M.B. Souza Dias, V.L. Borrasca, V. Stempliuk, 

M.H. Miyake, A. Colli, M.R. Araújo 

(São Paulo, BR) 

P1564 Burkholderia cepacia complex in an Italian 

cystic fibrosis centre: epidemiology and 

clinical course of patients infected with 

different Burkholderia cenocepacia RecA 

strains 

G. Manno, C. Dalmastri, S. Tabbacchioni, 

P. Vandamme, L. Minicucci, L. Romano, 

L. Chiarini, A. Bevivino 

(Genoa, Rome, I; Ghent, B)

12:00–13:00 

Hepatitis C 


P1565 Pegylated interferon-alpha2a and ribavirin in 

HIV-HCV co-infected patients 

G. Cariti, S. Bonora, F.G. De Rosa, O. Bargiacchi, 

S. Audagnotto, D. Aguilar, F. Lipani, M. Bonasso, 

C. Tettoni, A. Poggio, M. Gobber, P.G. Orsi, 

M. Anselmo, F. Indiveri, G. Ferrea, A. Sinicco, 

T. De Blasi, R. Raiteri, G. Di Perri (Turin, Verbania, 

Vercelli, Alessandria, Savona, Genoa, Sanremo, I) 

P1566 Compliance and response to PEG-IFNalpha 

and Ribavirin combined treatment of a special 

category of chronic hepatitis C patients, 

the ex-users of intravenously administered 

narcotic substances 

C. Drakoulis, E. Stavropoulou, E. Nikitidis, 

S. Nikolaou, C. Malli, E. Katsadorou, M. Minadaki 

(Piraeus, GR) 

P1567 Effects of combination treatment with 

interferon and ribavirin on endothelial cell 

inflammatory integrins and stress markers in 

advanced chronic hepatitis C 

I. Korzh, I. Fedotova, V. Nemtsova (Kharkov, UKR) 

P1568 Influence of interleukin-10 therapy on 

endothelial cell proteins in patients with 

chronic hepatitis C 

O. Korzh (Kharkov, UKR) 

P1569 Correlation between endothelial haemostatic 

markers in patients with chronic hepatitis C 

O. Korzh (Kharkov, UKR) 

P1570 The role of antibodies against NS5 protein of 

hepatitis C virus (HCV) and IgM antibodies 

against HCV as predictive factors to the 

treatment with interferon alpha in patients 

with chronic hepatitis C 

V. Mitsura (Gomel, BLR) 

P1571 Evaluation of the total hepatitis C virus core 

antigen in patients with chronic hepatitis: 

comparison with quantiplex branched 

DNA 3.0 

G. Giuliani, P. Musardo, L. Drago, A. Lombardi, 

M.R. Gismondo (Milan, I) 

P1572 Rapid and accurate quantitation of different 

HCV genotypes by optimisation of a new 

real-time PCR test 

L. Tagliaferro, P. Menegazzi, M. De Donno, 

J.L. McDermott, F. Bertolotti, I. Martini, 

O.E. Varnier (Lecce, Genoa, I) 

P1573 Genotyping distribution of hepatitis C virus 

in patients with HCV infection in Northern 

Greece 

A. Tatsiopoulos, K. Mandraveli, D. Papadopoulou, 

S. Alexiou-Daniel (Thessalonica, GR) 

P1574 Use of transcription mediated amplification 

method (TMA), line probe assay (LiPA) and 

branched DNA (bDNA) assay, to study chronic 

hepatitis C in a group of intravenous drug 

users 

M. Christofidou, G. Economides, 

G. Dimitracopoulos (Patras, GR) 

P1575 Molecular epidemiology of hepatitis C 

among drug users, correlation with clinical 

parameters, sexual behaviour and drugrelated 

risk behaviour 

C. Matheï, G. Robaeys, M. Van Ranst, 

P. Van Damme, F. Buntinx 

(Leuven, Genk, Antwerp, B) 

P1576 Evaluation of total HCV core antigen 

detection in hemodialysis patients 

A.I. Aller, L. Calbo, J.L. De Francisco, J.C. Alados, 

C. De Miguel (Jerez de la Frontera, E) 

P1577 Clinical evaluation of the male sexual partners 

of HCV-infected pregnant women 

E. Minola, C. Passerini Tosi, G. Rizzo, M. Arosio, 

A. Goglio, F. Suter (Bergamo, I) 

P1578 Outcome of pregnancy in hepatitis C virus 

infection 

A. Sariola, P. Koskela, P. Finne, A. Järvenpää, 

K. Melen, S. Riikonen, I. Julkunen (Helsinki, FIN) 

P1579 Prevalence of hepatitis C virus infection and 

risk factors in an incarcerated population in 

Iran 

Z Mohtasham Amiri, M. Rezvani, M.A. Jafari 

Shakib, R. Jafari Shakib, H. Asadi Nejad 

(Rasht, IR) 

P1580 HCV genotypes in the Slovak Republic 

K. Koncova, J. Kazar (Bratislava, SK) 

P1581 Genotypical profile of infection by HCV 

D. Blanco, A. Marin, I. Gonzalez, M. Nuñez, 

M. Viqueira, A. Gomez, J. Piqueras (Cartagena, E) 

P1582 Distribution of HCV genotypes among 

patients in São Paulo, Brazil 

H.H. Caiaffa Filho, A.Z.A. Latif, P.R. Canesin, 

A.C. Lucena, M.N. Burattini (São Paulo, BR) 


page 129


12:00–13:00 

Sexually transmitted diseases 

P1583 Prevalence of C. trachomatis infection in 

the general population and in a sexually 

transmitted disease centre in the Balearic 

Islands, Spain 

J. Reina, O. Gutiérrez, E. Ruiz de Gopegui, 

M. Gonzalez (Palma de Mallorca, E) 

P1584 Chlamydia trachomatis infection and risk of 

preterm birth 

V. Yonkova, V. Lyoutzkanova, V. Savouleva 

(Varna, BG) 

P1585 Prevalence of Chlamydia trachomatis in 

Istanbul among men with urethritis 

A. Agacfidan, H. Beka, M. Onel, A. Kadioglu, 

T. Lama (Istanbul, TR) 

P1586 The prevalence of pathogenic microorganisms 

in men with nongonococcal 

urethritis 

J. Tiodorovic, B. Tiodorovic, G. Tasic (Nis, YU) 

P1587 Microbiological aspects of male urethritis 

observed from 1990 to 2002 in a central 

military hospital, Algiers 

M. Naim, W. Amhis, A. Chabani, D. Tiouit 

(Algiers, DZ) 

P1588 Women prefer self-collection of vaginal 

swabs which are as effective for the diagnosis 

of Chlamydia trachomatis and Neisseria 

gonorrhoeae as urine, cervical swabs and 

clinician-collected vaginal swabs 

M. Chernesky, J. Lane, D. Martin, J. Jordan, 

D. Fuller, D. Willis, P. Fine, W. Janda, 

J. Schachter, E.W. Hook (Hamilton, CAN; 

San Diego, New Orleans, Pittsburgh, 

Indianapolis, Jacksonville, Houston, Chicago, 

San Francisco, Birmingham, USA) 

P1589 Comparison of sequence typing and 

opa- typing for discrimination of Neisseria 

gonorrhoeae 

N. Bilek, I.M.C. Martin, G. Kinghorn, B.G. Spratt, 

C.A. Ison (London, Sheffield, UK) 

P1590 Local outbreak of ciprofloxacin-resistant 

Neisseria gonorrhoeae in Finland 

P. Kärpänoja, L. Lindholm, A. Hakanen, 

K. Lounamo, H. Sarkkinen (Lahti, Turku, FIN) 

P1591 Characterisation of ciprofloxacin-resistant 

Neisseria gonorrhoeae isolated in Italy 

P. Stefanelli, C. Vasta, P. Mastrantonio (Rome, I) 


P1592 Antimicrobial resistance of Neisseria 

gonorrhoeae and emerging fluoroquinolone 

resistance in Russia 

M. Zoubkov, A. Kubanova, T. Vahnina, 

T. Priputnevich (Moscow, RUS) 

P1593 Susceptibilities of Neisseria gonorrhoeae and 

Ureaplasma urealyticum isolates from male 

patients with urethritis to several antibiotics 

including telithromycin 

D. Aydin, Ö. Küçükbasmaci, N. Gönüllü, Z. Aktas 


P1594 Occurrence of Ureaplasma urealyticum and 

Mycoplasma hominis among immigrant 

prostitutes and non-selected patients 

S. Noviello, V. Cuniato, F. Bellitti, E. Nocera, 

S. Esposito (Naples, I) 

P1595 Serological screening for sexually transmitted 

diseases among immigrants in Italy 

S. Noviello, V. Cuniato, F. Bellitti, E. Nocera, 

S. Esposito (Naples, I) 

P1596 Updated profile of infections in premature 

deliveries in the obstetrics department of 

a medical university, Gdansk 

J. Komarnicka, K. Leszczynska, A. Samet, 

K. Preis, D. Lautembach (Gdansk, PL) 

P1597 Incidence of simultaneous chlamydial 

and mycoplasma infection in women of 

reproductive age 

K. Avdeliodi, M. Simou, S. Tzortzatou, I. Glynou, 

H. Nikolaou, H. Kada (P.Psychiko, Athens, GR) 

P1598 Prevalence of mycoplasma in female genital 

tract and susceptibility to antimicrobial 

agents 

M. Simou, K. Avdeliodi, S. Tzortzatou, I. Glynou, 

T. Lazaraki, H. Kada (Athens, GR) 

P1599 Incidence and in vitro sensitivity of genital 

mycoplasmas to antibiotics 

J. Spiliopoulou, H. Panagou, A. Meletiou, 

M. Alexandrou, E. Zagotzidou, A. Vogiatzi 

(Athens, GR) 

P1600 Genome differences and detection of 

pathogenic Treponema pallidum subspecies 

P. Matejkova, D. Smajs, S.J. Norris, 

G.M. Weinstock (Brno, CZ; Houston, USA) 

P1601 Comparative genomics of Treponema 

pallidum ssp. pallidum and Treponema 

paraluiscuniculi 

D. Smajs, P. Matejkova, S.J. Norris, 

G.M. Weinstock (Brno, CZ; Houston, USA)


P1602 An outbreak of primary and secondary 

syphilis among HIV seropositive patients 

in Korea 

H.C. Jang, W.B. Park, K.D. Lee, C.S. Lee, 

S.W. Park, Y.J. Choi, H.B. Kim, M.D. Oh, 

K.W. Choe (Seoul, Cheonan, Goyang, KOR) 

P1603 Incidence of syphilis in AREA 2 of Madrid 

during four years: a retrospective study 

(2000–2003) 

A. Perkins, J. Rodriguez, A. Alonso, A. Perez de 

Ayala, M. López-Brea, C. Casal (Madrid, E) 

P1604 Epidemiology of syphilis in a hospital in Tunis 

Z. Amel, B. Lilia, S. Sameh, M. Kemiti (Tunis, TN) 

P1605 Sexually transmitted HAV 

C. Minari, G. Gubertini, G. Orlando, 

C. Pastecchia, A. Cargnel (Milan, I) 

P1606 Prevalence of sexually transmitted viruses 

in Polish commercial sex workers including 

HIV-seropositive individuals 

B. Bucholc, J. Slusarczyk, M. Drop, Z. Dajek 

(Warsaw, PL) 

P1607 Is systematic screning of hepatitis C virus 

in a sexually transmitted diseases clinics 

necessary? 

L. Metola, V. Ibarra, J.R. Blanco, L. Rosel, 

J.A. Oteo (Logroño, E) 

P1608 Clinical evolution of anal and cervical HPV 

displasic lesions in HIV-1 infected patients 

G. Orlando, C. Minari, M. Fasolo, R. Beretta, 

A. Cargnel (Milan, I) 

P1609 Bacterial vaginosis in patients with genital 

HPV infection 

A. Kuch, A. Szkaradkiewicz, P. Piêta, M. Wal, 

Z. Muszyñski (Poznan, PL) 

P1610 Testing for oncogenic HPV in PaP liquid 

preservative fluid (Tripath Sure Path) 

correlates with cytopathology and Digene 

sampler results 

J. Kapala, M. Chernesky, J. Patel, S. Chong, 

D. Jang, K. Biers, J. Mahony 

(Brampton, Hamilton, CAN) 

P1611 Epstein-Barr virus and cervix uterine cancer 

A. Szkaradkiewicz, M. Wal, A. Kuch, P. Piêta 

(Poznan, PL) 

P1612 Prospective study on the risk factors associated 

with cervical dysplasia and cervical carcinoma 

M. Petrican, A. Craciun, S. Tomasian 

(Constanta, RO) 

12:00–13:00 

Diagnostic methods: antibiotic susceptibility 

P1613 Direct susceptibility testing of positive Bac T 

Alert blood culture by disk diffusion and 

preliminary bacterial identification 

I. Mansoor, E. Deberg, P. Ninfa, C. Leroy 

(Baudour, B) 

P1614 Evaluation of the VITEK 2 system for rapid 

direct identification and susceptibility testing 

from positive blood cultures 

C. Berhin, Y. Glupczynski, Y. De Gheldre (Yvoir, B) 

P1615 Antibiotic susceptibility test on pathogens 

isolated in ICU using the Uro-Quick system 

S. Roveta, F. Cavallini, A. Marchese, E.A. Debbia 

(Genoa, I) 

P1616 Comparison of Phoenix, Vitek and Vitek 2 

automated identification and susceptibility 

testing systems 

D. Brown, T. Milne, D. Livermore 

(Cambridge, London, UK) 

P1617 The application of two disc methods and 

the E-test for detecting extended-spectrum 

beta-lactamases in clinical strains of 

K. pneumoniae and E. coli 

E. Andrzejewska, A. Szkaradkiewicz (Poznan, PL) 

P1618 Sensitivity and cost-effectiveness of different 

phenotypic methods for the detection and 

confirmation of extended-spectrum betalactamases 

including an inexpensive novel 

method 

R. Colodner, N. Keller, B. Chazan, R. Raz 

(Afula, Tel Hashomer, IL) 

P1619 Evaluation of the E-test MBL for detecting 

metallo-beta-lactamases in carbapenemresistant 

Pseudomonas aeruginosa isolates 

M. Maniati, S. Pournaras, Z. Bersos, A.N. Maniatis 

(Larissa, GR) 

P1620 Evaluation of BDXpert System for 

interpretation of antibiotic susceptibility 

testing results for Streptococcus species 

M. Deal, J. Pollitt, M. Gosnell, B. Turng, T. Wiles, 

D. Callihan, J. Reuben (Sparks, USA) 

P1621 Evaluation of cefepime with and without 

clavulanic acid for the detection of 

extended-spectrum beta-lactamases in 

Enterobacteriaceae species 

E. Smith Moland, T.J. Lockhart, J.A. Black, 

L.B. Olson, A. Hossain, N.D. Hanson, 

K.S. Thomson (Omaha, USA) 


page 131


P1622 Evaluation of the MicroScan ESBL Plus 

confirmation panel for Enterobacteriaceaeproducing 

extended-spectrum beta-lactamases 

E. Cercenado, N. García-Escribano, J. Garcia- 

Martinez, E. Bouza (Madrid, E) 

P1623 Evaluation of the ability of Italian laboratories 

to detect beta-lactam resistance phenotypes 

in Enterobacteriaceae: a proficiency study by 

the Associazione Microbiologi Clinici Italiani 

(AMCLI) 

G. Gesu, F. Luzzaro, G. Ortisi, S. Malandrin, 

A. Endimiani, L. Pagani, G. Rossolini 

on behalf of AMCLI Antimicrobials Study Committe 

P1624 Characteristics of methicillin-resistant 

Staphylococcus aureus undetected by Vitek 2 

V. Vernet-Garnier, D. Forte, L. Brasme, F. Bureau- 

Chalot, J.D. Capelle, J. Madoux, C. De Champs 

(Reims, F) 

P1625 Bench validation of methicillin resistance 

detection by Vitek 2 in clinical staphylococci 

isolates 

A. Wenger, I. Nahimana, G. Prod'hom, J. Bille, 

K. Jaton (Lausanne, CH) 

P1626 Detection of clinical MRSA strains in routine 

diagnostic laboratory 

M. Slomka, A. Szymanowska, A. Rokosz, 

A. Sawicka-Grzelak, M. Luczak (Warsaw, PL) 

P1627 Comparison of two methods for screening of 

MRSA carriers 

M. Cordova, A. Jacquet, H. Siegrist 

(La Chaux-de-Fonds, CH) 

P1628 Comparative study of various methods, 

NCCLS M27-A2, EUCAST and ATB Fungus 2 

(bioMérieux) for the in vitro antifungal 

susceptibility testing of Candida sp. 

C. Durussel, D. Parreno, L. Nougier, V. Monnin, 

G. Zambardi, J. Bille 

(Lausanne, CH; La Balme-les-Grottes, F) 

P1629 Evaluation of a new generation of Sabouraud 

gentamicine chloramphenicol medium for 

the isolation of yeasts and moulds in clinical 

specimens 

N. Velay, E. Basso, F. Madé, E. Tissier, F. Villeval 

(Craponne, F) 

P1630 Detection of hetero-resistant MRSA: 

Controlled comparison of oxacillin/cefoxitin 

susceptibility testing by disk diffusion, agar 

screen, Vitek-2 and BD Phoenix automated 

systems 

C. Nonhoff, G. Mascart, M.J. Struelens, 

C. Van Den Borre, O. Denis (Brussels, B) 


12:00 –13:00 

Diagnostic methods: serology 

P1631 Comparison of three commercial methods for 

the diagnosis of pertussis in single serum 

samples 

F. de Ory, M.-E. Guisasola, M. Fernández, 

T. Minguito, N. Herranz, J.-C. Sanz 

(Majadahonda, Madrid, E) 

P1632 An enzyme immunoassay for measuring 

specific IgG antibodies to tetanus toxoid 

R. Budd, C. Budd, F. Alcock, R. George, 

K. Broughton, A. Bradwell 

(Birmingham, London, UK) 

P1633 A new enzyme immunoassay for the 

measurement of specific IgG antibodies 

to diphtheria toxoid and correlation with 

the Vero Cell Assay 

R. Budd, D. Taylor, F. Alcock, R. George, 

K. Broughton, A. Bradwell 

(Birmingham, London, UK) 

P1634 Application of gene recombination and 

chromatography of bio-affinity for production 

of the purified Yersinia enterocolitica protein 

antigens – use of the recombinant YopD 

protein in serodiagnosis of enteric illness and 

reactive arthritis 

W. Rastawicki, R. Gierczyñski, M. Jagielski, 

B. Kwiatkowska (Warsaw, PL) 

P1636 Quantitative detection of anti-Chlamydia 

pneumoniae IgG and IgA antibodies by ELISA: 

comparison to the microimmunofluorescence 

test 

D. Taglialatela, G. Anniballo, M.-L. Genna, 

V. Formicola, E. de Simone (Naples, I) 

P1637 Evaluation of Mycoplasma pneumoniae 

commercial tests for detection of serum 

antibodies using PCR as “the gold standard” 

M.F.C. Beersma, K. Dirven, H.-J. Gerritsen, 

A.P. van Dam, E.C. Claas, H. Goossens 

(Leiden, NL; Antwerp, B) 

P1638 Recombinant antigens of Ureaplasma spp. as 

a possible tool for a serological test 

F. Echahidi, G. Muyldermans, O. Soetens, 

S. Lauwers, A. Naessens (Brussels, B)


P1639 Syphilis Fast, a rapid treponemal test for 

the serodiagnosis of syphilis 

P. Tajada Alegre, M. Gutiérrez, R. De-Julián, 

A. Morente, M. García-Collía, M. Baquero, 

A. Pérez-Rivilla, J.L. Gómez-Garcés (Madrid, E) 

P1640 A multiplexed syphilis IgM serological test 

for the diagnosis of Treponema pallidum 

infection 

H. Yu, S. Binder, F. Torres, C. Hixson, S. Garcia, 

J. Wang, P. Chen (Hercules, USA) 

P1641 Evaluation of GLP antigen for serodiagnosis 

of human leptospirosis 

E. Caló Romero, R. Morozetti Blanco, C. Motta 

Bernardo, M.C. Outeiro Gorla (São Paulo, BR) 

P1642 Comparison of three different Toxocara ELISA 

and Western blotting methods in respect 

of sensitivity and specificity 

J. Danka, I. Kucsera, E. Orosz, Z. Szénási 


P1643 Evaluation of multiplexed IgG and IgM 

immunoassays for infectious mononucleosis 

and Epstein-Barr virus using the Bio-Rad 

BioPlex 2200 immunoassay analyser 

R. Bruehl, H. Scholz, L. Cuadra, F. Torres, 

J. Wang, R. Kaul, K. Yu, P. Chen, S. Binder 

(Hercules, USA) 

P1644 Evaluation of sensitivity and specificity of six 

combined P24 antigen and HIV antibody 

screening assays 

T.D. Ly, S. Laperche, C. Brennan, A. Vallari, 

A. Ebel, J. Hunt, L. Martin, D. Daghfal, S. Devare 

(Ivry sur Seine, Paris, F; Illinois, USA) 

P1645 Evaluation of sensitivity and specificity of 

a new generation of Immunocomb II HCV 

for the detection of anti-hepatitis C virus 

antibodies 

P. Veillon, A. Calvo, F. Lunel-Fabiani 

(Angers, Coubevoie, F) 

P1646 Western immunoblotting for serologic 

diagnosis of human candidosis 

F. Persat, D. Martin, M.A. Piens, S. Picot (Lyon, F) 

P1647 Advanced serological tests for the diagnosis 

of African tick bite fever 

M. Jensenius, P.-E. Fournier, S. Vene, S. Ringertz, 

B. Myrvang, D. Raoult 

(Oslo, N; Marseille, F; Solna, S) 

12:00–13:00 

Diagnostic methods: blood culture 

P1648 Evaluation of two procedures for direct 

inoculation of Gram-negative aerobic and 

facultative anaerobic bacteria from positive 

BACTEC blood cultures into the Phoenix 

automated microbiology system 

H. De Beenhouwer, M. Struelens, E. Perea, 

I. Autenrieth 

(Aalst, Brussels, B; Seville, E; Tubingen, D) 

P1649 Clinical and organisational factors associated 

with negative blood cultures from general 

internal medicine wards 

B.P. Ehrenstein, V. Ehrenstein, C. Henke, 

H.J. Linde, J. Schölmerich, T. Glück 

(Regensburg, D; Boston, USA) 

P1650 Reducing the rate of blood culture 

contamination 

A. Itzhaki, T. Lazarovitch, K. Ovadia, I. Gazit, 

J. Karpuch (Zrifin, IL) 

P1651 Comparison percentage of blood culture 

contamination in four hospital units and 

corrective sampling and processing after 

training 

M. Yaghobi (Tehran, IR) 

P1652 Prospective study to evaluate differential 

time-to-positivity in the diagnosis of portrelated 

bloodstream infection 

J.L. del Pozo León, A. Aguinaga Pérez, 

S. Hernáez Crespo, M. Lamata Subero, 

A. Rodríguez Macías, M.F. Rubio Vallejo, 

M. Fdez-Alonso, J. Leiva León (Pamplona, E) 

P1653 Procalcitonin rapid test in the diagnosis of 

sepsis 

K. Grozdanovski, Z. Milenkovic, P. Kalamaras, 

K. Karovski, V. Urosevic, D. Jovanovska, 

M. Cvetanovska, V. Semenakova (Skopje, MK) 

P1654 Usefulness of plasma procalcitonin in 

diagnosis of microbial infection among 

adults patients 

D. Dimou, M. Belechri, N. Marougas, 

N. Ioakimides, A. Karali, C. Kotsovassilis, 

P. Tsiodra, S. Chini, C. Keramidas (Athens, GR) 

P1655 Should procalcitonin be introduced in the 

diagnostic criteria for the systemic 

inflammatory response syndrome and sepsis? 

E.J. Giamarellos-Bourboulis, P. Grecka, 

P. Giannopoulou, D. Voros, K. Mandragos, 

H. Giamarellou (Athens, GR) 


page 133


P1656 Procalcitonin as a diagnostic aid in 

osteomyelitis and septic arthritis 

Y. Butbul-Aviel, R. Halevy, A. Koren, W. Sakran 

(Afula, IL) 

P1657 Comparison of the time-to-positivity of hubblood 

versus peripheral-blood cultures as 

useful tool for diagnosing catheter-related 

infection 

V. Mirovic, B. Tomanovic (Belgrade, CS) 

P1658 Comparison of the VersaTREK to the ESP 

Culture System II for blood cultures 

V. LaBombardi, D. Fett, A. Kamel, N. Sullivan 

(New York, Sun Prairie, USA) 

P1659 Comparison of the effect of delayed entry into 

two different blood culture systems (Bactec 

9240 and BacT/Alert 3D) on culture positivity 

O.A. Akan, E. Yildiz (Ankara, TR) 

P1660 The diagnosis of brucellosis by use of 

BACTEC 9050 blood culture system 

H. Uncu, T. Turunc, Y. Demiroglu, H. Arslan 

(Adana, Ankara, TR) 

P1661 Modification of “gold standard” method for 

the diagnosis of Chlamydia trachomatis 

infection using peripheral blood leukocyte 

culture 

T. Saralidze, T. Shvelidze, P. Gabunia, 

L. Mohchevishvili, E. Saralidze (Tbilisi, GEO) 

13:00–14:00 

Community-acquired infections 

P1662 Infections due to Abiotrophia defectiva and 

Granulicatella adiacens: identification 

by sequencing of 16S rDNA and clinical 

manifestations 

L. Senn, K. Jaton, A. Wenger, J. Bille, T. Calandra, 

G. Prod'hom (Lausanne, CH) 

P1663 Mediterranean spotted fever: 

study of 29 cases 

E. Louro, A. Campos, J. Leitão, A. Carvalho, 

R. Santos, C. Reis, E. Almiro, A. Porto 

(Coimbra, P) 

P1664 A rare cause of wound infection: 

Shewanella putrefaciens 

C. Bulut, C. Gökcek, G. Ertem, Y. Erdem, 

M.A. Bayar, E. Karakoç, N. Tülek (Ankara, TR) 

P1665 Pathogens isolated from ambulatory patients 

with acute upper respiratory tract disease 

A. Samet, E. Dziemaszkiewicz, E. Arlukowicz, 

J. Komarnicka (Gdansk, PL) 


P1666 Characteristics of microbiologic profile in 

cervical samples of pregnant women and 

non-pregnant healthy young women 

V. Kaliterna, N. Kucisec-Tepes, L. Pejkovic, 

E. Borzic, Z. Barisic, V. Zoranic, I. Jelicic 

(Split, Zagreb, HR) 

P1667 Respiratory symptoms during leptospirosis: 

a retrospective study of 9 patients 

P. Tattevin, S. Jauréguiberry, M. Dupont, 

G. Léveiller, R. Flicoteaux, C. Arvieux, 

C. Michelet (Rennes, F) 

P1668 Abscesses of skin and skin structures: 

insights from a randomised study of 

ertapenem vs piperacillin-tazobactam 

R. Gesser, K. McCarroll, C. Chan, M. DiNubile 

(West Point, USA) 

P1669 Classification of clinically-relevant microorganisms 

in non-medical environments 

D. Bowers, T. Domanski (Annapolis, USA) 

P1670 Comparison of azithromycin and amoxicillin 

for treatment of adult patients with solitary 

erythema migrans 

S. Lotric-Furlan, M. Logar, V. Maraspin, 

J. Cimperman, T. Jurca, F. Strle (Ljubljana, SI) 

P1671 Refractory gingivitis in a patient with 

osseointegrated implant by the transmission 

of Actinobacillus actinomycetemcomitans 

Z. Barna, Á. Tóth, Z. Budai (Budapest, HUN) 

P1672 The micro-organisms isolated from sinovial 

fluid 

N. Balaban, S. Suzuk, B. Urunal, H. Bodur, 

V. Yetener (Ankara, TR) 

P1673 Charasteristics of cutaneous anthrax in 

Turkey 

N. Baykam, O. Ergonul, S. Eren, A. Kocagul, 

H. Hasman, B. Dokuzoguz (Ankara, TR) 

P1674 Prevalence beta haemolytic streptococci from 

throat swabs in health care area from 

Pontevedra, Spain 

V. Pulian, M. Hernandez, P. Alvarez, M.A. Pascual, 

M. Garcia (Pontevedra, E) 

P1675 Acute bacterial sinusitis: 

43 cases of complications 

D. Stoll and the ORLI group 

P1676 Distribution of sites of infection and T-types 

of beta-haemolytic streptococci group A 

during a period of hyperendemicity in a 

Danish region 

T. Ejlertsen, K. Ekelund, H.C. Schønheyder 

(Aalborg, Copenhagen, DK)


P1677 Assessment of documentation of markers of 

sepsis and appropriateness of antimicrobial 

prescribing in an acute medical admission 

unit prior to and following the introduction 

of a sepsis stamp 

D. Robson, A.M. Cadwgan, K.D. Wares, 

R.B.S. Laing, J.G. Douglas, A.R. Mackenzie 


P1678 Levofloxacin experience in a general hospital 

J. De La Torre, J.L. Prada, A. Del Arco, J. Aguilar, 

F. Moreno, N. Montiel, I. Lopez (Marbella, E) 

P1680 Characterisation of Staphylococcus xylosus 

strains isolated from humans clinical material 

D. Kuboskova, I. Sedlacek, P. Svec, P. Petras 

(Brno, Prague, CZ) 

P1681 Staphylococcus lugdunensis: an overlooked 

but easy identifiable, frequent cause of 

abscesses in general practice 

S. Böcher, J. Prag (Viborg, DK) 

P1682 Frequency and clinical spectrum of 

Staphylococcus lugdunensis infections – 

a French national survey: preliminary results 

V. Blanc, R. Sanchez – Collège de Bactériologie 

Virologie Hygiène des Hôpitaux 

(ColBVH Study Group), France 

P1683 Changes in management and outcome of 

Staphylococcus aureus bacteraemia 

1996–2003 

S. Bold, P. Vernazza, S. Henz, G. Eich 

(St. Gallen, CH) 

P1684 Clinical aspects and risk factors for mortality 

of Staphylococcus aureus sepsis in a Swiss 

tertiary centre 

C. Kaech, L. Elzi, P. Sendi, R. Frei, U. Fluckiger 

(Basle, CH) 

P1685 Microbiological results from a randomised, 

open-label study of ertapenem vs 

piperacillin/tazobactam for the treatment 

of community-acquired intra-abdominal 

infections requiring surgery 

A. Dela Pena, W. Asperger, B. Warren, R. Kafka, 

R. Raz, M. Shivaprakash, F. Vrijens, H. Giezek, 

C. Chan, M. Stek (Manila, PH; Halle, D; Parow, ZA; 

Innsbruck, A; Afula, IL; Whitehouse Station, USA; 

Brussels, B) 

P1686 Ertapenem versus piperacillin/tazobactam for 

the treatment of intra-abdominal infections 

requiring surgical intervention (OASIS-1): 

results of a prospective, randomized, 

open-label study 

A. Dela Pena, W. Asperger, F. Köckerling, R. Raz, 

R. Kafka, B. Warren, M. Shivaprakash, F. Vrijens, 

H. Giezek, C. Chan 

(Manila, PH; Halle, Hannover, D; Afula, IL; 

Innsbruck, A; Parow, ZA; Whitehouse Station, USA; 

Brussels, B) 

P1687 A prospective randomised trial comparing 

cefepime plus metronidazole and imipenemcilastatin 

for the treatment of intra-abdominal 

infections 

J. Garbino, P. Villiger, A. Caviezel, I. Uckay, 

P. Morel, R. Matulionyte, A. Ondrusova, 

M. Puppo, D. Lew (Geneva, CH) 

P1688 Microbiology and empirical treatment 

of pyogenic liver abscesses: 

analysis of 105 cases 

I. Terrancle, F. Mateos, L. Fuentes, R. Arjona, 

J.L. Pérez-Arellano, B. Roca, F. Marcos, 

I. Tárraga, J.J. Blanch, A. Hdez-Belmonte, 

E. Martínez-Alfaro 

from the Infectious Diseases Group of the 

Spanish Society for Internal Medicine (SEMI) 

P1689 Pyogenic liver abscess. A multicentre 

experience in management 

F. Mateos, I. Terrancle, R. Arjona, L. Fuentes, 

M. Hernandez, B. Roca, F. Marcos, I. Tárraga, 

J.J. Blanch, E. Martínez-Alfaro 

from the Infectious Diseases Group of the 

Spanish Society for Internal Medicine (SEMI) 

P1690 Two vs four weeks ceftriaxone+metranidazol 

treatment in percutaneously drained 

pyogenic liver absecess: preliminary report 

C. Agalar, S. Soylu, H. Donmez, F. Agalar, 

E. Tutuncu, S. Gul, C. Diri, R. Turkyilmaz 

(Ankara, TR) 

P1691 Micro-organisms isolated from exit site of 

peritoneal catheters in patients submitted 

to chronic ambulatory peritoneal dialysis 

E. Garcia-Peñuela, A. Perez de Ayala, 

D. Domingo, D. Monclus, A. Cirugeda, 

M. Lopez-Brea (Madrid, E) 

P1692 Vertebral osteomyelitis in patients with 

HIV-infection 

M.E. Jiménez-Mejías, J.D. Colmenero, C. López 

Casanova, J.D. Ruiz-Mesa, J. Palomino-Nicás, 

J.M. Reguera Iglesias, A. Plata, J. Pachón-Díaz 

(Seville, Málaga, E) 


page 135


P1693 Imipenem-cilastatin treatment of osteo - 

articular infections caused by multiresistant 

Gram-negative rods 

M. Rottman, J.-N. Martin, P. Leclerc, E. Ronco, 

A. Lortat-Jacob, J.-L. Gaillard, P. Piriou 

(Garches, Boulogne Billancourt, F) 

P1694 Staphyloccocus aureus versus Gram-negative 

bacilli pyogenic vertebral osteomyelitis. 

A clinical, biological and radiological 

comparative study 

M.A. Barón Ramos, E. Jimenez-Mejías, J.D. Ruiz 

Mesa, J. Palomino-Nicás, J.M. Reguera Iglesias, 

J. Chacón, J. Pachón, J.D. Colmenero 

(Málaga, Seville, E) 

P1695 Characterisation of Salmonella paratyphi 

A strains with reduced susceptibility to 

quinolone isolated from an outbreak in Korea 

S. Lee, D. Kim, C. Chang, H. Kim (Busan, KOR) 

P1696 Rise in isolation rates and nalidixic acid 

resistance in Salmonella hadar due to 

common strains among poultry and humans 

L. Politi, P.T. Tassios, L.S. Tzouvelekis, 

M. Lambiri, A. Kansouzidou, M. Pasiotou, 

K. Mellou, N. Vakalis, J. Kourea-Kremastinou, 

T. Panagiotopoulos, N.J. Legakis 

(Athens, Thessalonica, Halkida, GR) 

P1697 Investigation of clinical and laboratory 

findings of antibiotic-associated diarrhoea 

N. Yapar, A. Sener, B. Karaca, M. Yücesoy, 

H. Tarakci, N. Cakir, A. Yüce (Izmir, TR) 

P1698 Serotyping and susceptibility testing of 

shigella isolates during summer outbreak 

of 2003 in an Iranian hospital, Tehran 

M. Rahbar, K. Bahar, B. Kia Darbandisari, 

M. Deldari (Tehran, IR) 

P1699 Characterisation, genomic location and 

distribution of the cytolethal distending 

toxin genes in Shiga toxin-producing 

Escherichia coli strains of non-O157 

serogroups 

M. Bielaszewska, M. Fell, L. Greune, R. Prager, 

A. Fruth, H. Tschäpe, M.A. Schmidt, H. Karch 

(Munster, Wernigerode, D) 

P1700 Vibrio cholerae in the South-East of Iran 

H.A. Khazaei, N. Rezaei, G.R. Bagheri 

(Zabol, Tehran, IR) 

P1701 Neonatal septicaemia in dogs by Klebsiella 

pneumoniae 

A. Madio, G. Greco, M. Corrente, M. Totaro, 

C. Desario, M. Campolo, G. Marsullo, 

D. Buonavoglia (Valenzano, Naples, I) 


13:00–14:00 

Quinolones in vitro studies 

P1702 Lower levels of in vitro nonsusceptibility 

to Moxifloxacin compared to other fluoroquinolones 

in Canadian clinical isolates 

of Streptococcus pneumoniae 

J. Powis, J. Fuller, O. Vanderkooi, K. Green, 

D. Low – Canadian Bacterial Surveillance Network 

P1703 Comparative bactericidal activity of 

moxifloxacin, gatifloxacin, garenoxacin, and 

levofloxacin at concentrations simulating 

Cmax and 1 ⁄ 2 Cmax 

H. Musgrave, S. Campbell, C. Howley, 

R.J. Davidson (Halifax, CAN) 

P1704 Comparative in vitro activity of fluoro - 

quinolones against clinical isolates of 

Streptococcus pneumoniae 

R. Alonso, R. Cisterna (Vitoria-Gasteiz, Bilbao, E) 

P1705 The relationship between the mutant 

prevention concentration and killing by 

ciprofloxacin and levofloxacin for clinical 

isolates of Pseudomonas aeruginosa 

J. Blondeau, G. Hansen (Saskatoon, CAN) 

P1706 Activity of moxifloxacin against 12 selected 

clinical B. fragilis strains compared with 

seven other agents investigated by time-kill 

kinetics 

R. Schaumann, E. Rabenhorst, M. Funke, 

A. Rodloff (Leipzig, D) 

P1707 Selection of resistance in Pseudomonas 

aeruginosa and Acinetobacter spp. by 

levofloxacin and ciprofloxacin alone and in 

combination with beta-lactams and an 

aminoglycoside 

E. De Vecchi, L. Drago, L. Nicola, A. Colombo, 

M.R. Gismondo (Milan, I) 

P1708 Mutant prevention concentrations of 

ciprofloxacin and enrofloxacin against 

Salmonella enterica in vitro 

L. Randall, S. Cooles, M. Woodward 

(New Haw, UK) 

P1709 Comparative in vitro resistance of the new 

fluoroquinolones among aerobic Gramnegative 

bacilli resistant to amikacin in a 

hospital setting: a three-year study 

E. Arroyo, D. Vera, C. Rivera-Vazquez, 

G. Gonzalez, S. Saavedra, J. Gutierrez, 

C. Ramirez-Ronda (San Juan, PR)


P1710 Baselining levofloxacin activity against Gramnegative 

organisms collected in five European 

countries: first results from the 2003 GLOBAL 

Surveillance 

M. Jones, R. Blosser, J. Karlowsky, D. Sahm 

(Herndon, USA) 

P1711 In vitro activity of three different fluor - 

quinolones alone, or in combination against 

Pseudomonas aeruginosa 

J. Parra, A. Peña, T. Escobar, M. Martinez, 

N. Chueca, M.-A. Martinez, G. Piédrola, 

J. Hernández-Quero (Granada, E) 

P1712 Effect of quinolones on Plesiomonas 

shigelloides 

A. Hostacka, I. Ciznar, R. Melkova, K. Krovacek 

(Bratislava, SK; Uppsala, S) 

P1713 Comparitive in vitro activities of ciprofloxacin, 

ofloxacin and levofloxacin against nonfermentative 

bacteria isolated from 


F. Ergin, H. Arslan, O. Kurt Azap, S. Karaman, 

G. Yapar (Ankara, TR) 

13:00–14:00 

Antimicrobial resistance mechanisms – III 

P1714 Phenotypic and genotypic characterisation 

of antimicrobial resistance in Egyptian 

Escherichia coli isolates 

M.H.M. Al-Agamy, M.S-E.M. Ashour 

(Bonn, D; Cairo, EGY) 

P1715 gyrA mutations and quinolone resistance 

in Salmonella enteritidis and Salmonella 

typhimurium 

N. Delgado Ronda, J.L. Muñoz Bellido, 

M.I. García García, S. Muñoz Criado, M.C. Sáenz 

González, J.A. García Rodríguez (Salamanca, E) 

P1716 First report of a TEM-26 beta-lactamase with 

mutations conferring resistance to piperacillin/ 

tazobactam 

T. Collyns, F. M'Zali, C. Nice, D. Roberts, M. Wilcox 

(Leeds, UK) 

P1717 New isolation of an integron-located VEB-1 

extended-spectrum beta-lactamase in a 

P. mirabilis clinical strain 

N. Camino, B. Rodés, T. Alarcón, C. Toro, 

A. Morente, M. Martínez-Padial, V. Soriano, 

M. Baquero (Madrid, E) 

P1718 Ceftazidim-resistant Escherichia coli and 

Klebsiella pneumoniae isolates from four 

Turkish hospitals: identification of TEM-, 

SHV-, and GES-type beta lactamases 

S. Gündes, F. Kolayli, K. Demirdag, M. Günaydin, 

M. Altindis, R. Caylan, S. Hosoglu, H. Vahaboglu 

(Kocaeli, Elazig, Samsun, Afyon, Trabzon, 

Diyarbakir, TR) 

P1719 Third generation cephalosporin-resistant 

Escherichia coli from a paediatric hospital 

in Iasi, Romania 

R. Filip, V. Miriagou, S. Vourli, G. Coman, 

E. Tzelepi (Iasi, RO; Athens, GR) 

P1720 Characterisation of two novels 6'-N-amino - 

glycoside acetyltransferase genes, aac(6')-30 

and aac(6')-31, found in blaIMP-16 and blaIMP-1 

Pseudomonas aeruginosa strains carrying 

integron 

R.E. Mendes, M.A. Toleman, R.N. Jones, 

T.R. Walsh (Bristol, UK; North Liberty, USA) 

P1721 Biological cost of fusidic acid resistance in 


S. Besier, A. Ludwig, V. Brade, T.A. Wichelhaus 

(Frankfurt/ Main, D) 

P1722 Characterisation of In77, a class 1 plasmidlocated 

integron carrying the novel metallobeta-latamase 

gene blaGIM-1 

M. Castanheira, M.A. Toleman, R.E. Mendes, 



P1723 The effect of large inocula on in vitro 

activities of penicillin-inhibitor combinations 

and cefoperazone-sulbactam against ESBLproducing 

Escherichia coli and Klebsiella 

pneumoniae strains 

M. Edelstein, I. Edelstein, D. Semchenkova, 


P1724 Tn501-like transposons carrying novel 

blaVIM-4 metallo-ß-lactamase (MBL) gene 

cassettes in Poland and GIM-1 in Germany: 

report from the SENTRY antimicrobial 

surveillance programme 

M. Toleman, R. Mendes, M. Castanheira, 

J. Patzer, R. Jones, T. Walsh (Bristol, UK) 

P1725 Quinolone-resistance mechanisms of 

Stenotrophomonas maltophilia strains from 

Greek hospitals 

C. Masgala, I. Galani, M. Souli, Z. Chryssouli, 

H. Giamarellou (Athens, GR) 


page 137


P1726 Survey of extended-spectrum beta-lactamase 

in clinical isolates of Pseudomonas and 

Acinetobacter species 

S. Günde, H. Üçkarde, A. Karadenizli, M. Rüzgar, 

F. Özkan, A. Willke (Kocaeli, TR) 

P1727 Biochemical characterisation of VIM-7, a new 

VIM variant produced by a Pseudomomas 

aeruginosa clinical isolate from Texas 

M. Castanheira, T.A. Murphy, M.A. Toleman, 



P1728 Distribution and association of mef(A/E), 

erm(B) and tet(M) genes in erythromycin 

resistant S. pneumoniae and oral streptococci 

M. Santagati, C. Cascone, C. Fichera, T. Bertuccio, 

M. Mezzatesta, G. Guardo, S. Stefani (Catania, I) 

P1729 Mechanisms of resistance in 17 unrelated 

Escherichia coli strains of different origins 

with a multiple-antibiotic-resistance 

phenotype 

Y. Sáenz, L. Briñas, J. Ruiz, M. Zarazaga, J. Vila, 

C. Torres (Logroño, Barcelona, E) 

P1730 Genetic analysis of fluoroquinolone-resistant 

Acinetobacter baumannii isolates from Korea 

J.K. Lee, Y.S. Yoo, Y.S. Lee, J.I. Yoo, B.S. Kim 

(Seoul, KOR) 

P1731 CTX-M-type extended-spectrum betalactamases 

in commensal Escherichia coli 

from healthy children living in urban areas 

of Bolivia and Peru 

L. Pallecchi, M. Malossi, A. Mantella, 

A. Bartoloni, C. Trigoso, H. Guerra, F. Paradisi, 

G. Kronvall, G.M. Rossolini 

(Siena, Florence, I; La Paz, BOL; Lima, PE; 

Stockholm, S) 

P1732 Characterisation of extended-spectrum 

beta-lactamases in Escherichia coli strains 

recovered in a Spanish hospital 

L. Briñas, M. Lantero, I. de Diego, M. Alvarez, 

M. Zarazaga, C. Torres (Logroño, Oviedo, E) 

P1733 Molecular characterisation of two 

multiresistent clinical isolates of 

Chlamydia trachomatis 

O. Misyurina, E. Chipitsyna, J. Finashutina, 

V. Lazarev, A. Savicheva, V.M. Govorun 

(Moscow, RUS) 

P1734 The presence of tetracycline resistance 

determinants and the susceptibility for 

tigecycline and minocycline 

A. Fluit, A. Florijn, J. Verhoef, D. Milatovic 

(Utrecht, NL) 


P1735 Correlation of the mutation potential of 

Acinetobacter baumannii clinical isolates 

with alterations in the mutS gene 

S.E. Davies, S. Brown, S.G.B. Amyes 

(Edinburgh, UK) 

P1736 Examination of the carbapenem resistance 

gene activation mechanisms of imipenemresistant 

Bacteroides fragilis isolates from 

the UK 

J. Soki, J.S. Brazier, E. Fodor, M. Gal, E. Urban, 

E. Nagy, B.I. Duerden (Szeged, HUN; Cardiff, UK) 

P1737 Evaluation of the Salmonella typhimurium 

proteome by semi-automated two 

dimensional HPLC-mass spectrometry; 

detection of proteins implicated in multiple 

antibiotic resistance 

N. Coldham, M.J. Woodward (Surrey, UK) 

P1738 Characterisation of the mechanism of 

resistance to several antimicrobial agents in 

Salmonella clinical isolates causing traveller’s 

diarrhoea 

R. Cabrera, J. Ruiz, F. Marco, M. Arroyo, 

A. Aladueña, M. Usera, M. Jiménez de Anta, 

J. Gascón, J. Vila (Barcelona, Madrid, E) 

P1739 Gene for aac(6')-Ib, conferring resistance 

to amikacin, found in four different isolates 

of enterobacteria 

Z. Gonzalez-Lama, M. Fernandez-Burriel, 

P. Lupiola, A.M. Lamas, R. Alonso 

(Las Palmas de Gran Canaria, E) 

13:00–14:00 

Antimicrobial susceptibility in Gram-positive 

bacteria 

P1740 Resistance rates and resistance mechanisms 

of S. pneumoniae strains isolated from 

8 European countries: 

Final report of the PNEUMOWORLD study 

R. Reinert, S. Reinert, P. Appelbaum, M. Cil, 

R. Lütticken, A. Al-Lahham 

Pneumoworld Study Group 

P1741 European surveillance study on antibiotic 

sensitivity of Propionibacterium acnes strains 

C.E. Nord, C. Oprica – ESCMID Study Group on 

Antimicrobial Resistance in Anaerobic Bacteria 

(ESGARAB) 

P1742 Increasing erythromycin MICs within 

Canadian Streptococcus pneumoniae isolates 

with the M phenotype 

J. Powis, S. Pong-Porter, J. Fuller, D. Low – 

Canadian Bacterial Surveillance Network


P1743 Comparison of daptomycin and vancomycin 

MIC results by NCCLS, SFM, DIN and SRGA 

methods 

L. Koeth, R. Leclercq, A. Rodloff, R. Smyth 

(Westlake, USA; Caen, F; Leipzig, D; Vaxjo, S) 

P1744 Application of the mutant prevention 

concentration for Streptococcus pneumoniae 

against azithromycin, clarithromycin and 

erythromycin 

J. Blondeau, K. Metzler, S. Borsos 

(Saskatoon, CAN) 

P1745 Activity of daptomycin against clinical and 

environmental enterococci from Portugal 

C. Novais, J.C. Sousa, T.M. Coque, L. Peixe 

and the Portuguese Resistance Study Group 

P1746 Antimicrobial susceptibility patterns and 

macrolide resistance genes of betahaemolytic 

streptococci in Korea 

Y. Uh, I.H. Jang, G.Y. Hwang, M.K. Lee, 

K.J. Yoon, H.Y. Kim (Wonju, KOR) 

P1747 In vitro activity of daptomycin against a range 

of Staphylococcus aureus and Enterococcus 

isolates: first results from Turkey 

H. Arslan, Ö. Kurt Azap, F. Ergin, S. Karaman, 

E. Oruç (Ankara, TR) 

P1748 Time-kill evaluation of the in vitro activity 

of ertapenem against S. pneumoniae 

A. Marchese, L. Gualco, G. Schito (Genoa, I) 

P1749 Activity of ertapenem and 19 other 

antimicrobials against Streptococcus 

pneumoniae and Haemophilus influenzae 

isolated from the respiratory tract showing 

resistance mechanisms to betalactam 

antibiotics 

J.L. Gómez-Garcés, A. Alhambra Mosquera, 

J.I. Alós Cortés (Madrid, E) 

P1750 Daptomycin in vitro activity tested against 

2,221 Gram-positive strains collected from 

European hospitals, 2002 

H. Sader, J. Streit, T. Fritsche, R. Jones 


P1751 Activity of telithromycin against erythromycin 

susceptible and resistant Streptococcus 

pneumoniae isolates from adults with 

invasive infections 

M. Ortega, F. Marco, M. Almela, J. Puig de la 

Bellacasa, A. Soriano, J. Mensa (Barcelona, E) 

P1752 In vitro activities of linezolid, moxifloxacin, 

quinupristin/dalfopristin and tigecycline 

against recent clinical isolates of Staphylococcus 

spp. in Spain 

O. Cuevas, E. Cercenado, J.V. Guinea, 

M.E. Escobar, A. Blázquez, E. Bouza 

Staphylococcus Study Group 

P1753 Comparison of four commercially available 

systems for antimicrobial susceptibility 

testing of Streptococcus pneumoniae 

R. Rennie, C. Brosnikoff, L. Turnbull, 

S. Shokoples, M. Lovgren, J. Galbraith, C. Brown, 

L. Kipke, N. Hart (Edmonton, CAN) 

P1754 Comparison of the E-test and the agar 

dilution method for glycopeptide 

susceptibility testing of staphylococci 

M. Maniati, Z. Bersos, F. Kontos, I. Spiliopoulou, 

L. Spaliara, D. Mylona-Petropoulou, 

E. Malamou-Lada, C. Koutsia-Carouzou, 

E. Petinaki, A. Maniatis 

(Larissa, Patras, Athens, GR) 

P1755 Antibiotic resistance of enterococci isolated 

from blood and urine cultures during 

2002–2003 

H. Konstadakopoulou-Papadaki, S. Botsari, 

A. Koutoumanis, M. Tsimoraga, G. Kouppari 

(Athens, GR) 

P1756 Resistance to beta-lactams, macrolides, 

ketolides and newer fluoroquinolones in 

nasopharyngeal pneumococci with reduced 

susceptibility to ciprofloxacin 

J.L. Muñoz Bellido, R. Marín Jiménez, 

S. Hernández Iglesias, J.A. García-Rodríguez 

(Salamanca, E) 

P1757 Susceptibility of Streptococcus anginosus 

group isolates from dental abscesses and 

abscesses of fascial spaces of the face and 

neck 

G. Bancescu, A. Bancescu, C. Defta, M. Pana, 

D. Ionescu, S. Alecu, S. Dumitriu (Bucharest, RO) 

P1758 Comparative in vitro activity of telithromycin 

against viridans group streptococci 

C.-J. Soussy, C. Lascols, C. Dib, N. Moniot-Ville 

(Créteil, Paris, F) 

P1759 In vitro susceptibility of Streptococcus 

pneumoniae to ertapenem and other 

antibiotics 

Z. Samra, O. Ofir, I. Shalit (Petach -Tiqua, IL) 

P1760 Trend of Streptococcus pyogenes 

antimicrobial resistance in Reggio Emilia, Italy 

L. Ricci, A. Polese, G. Bertoldi, L. Vecchia 

(Reggio Emilia, I) 


page 139


P1761 In vitro activity and synergism studies of 

linezolid alone or in combination with several 

antimicrobial agents against Nocardia spp. 

M.-F. Tripodi, R. Fortunato, C. Farina, G. Ruggiero, 

R. Utili (Naples, Milan, I) 

P1762 Effect of pH, media and inoculum size on 

telavancin (TD-6424) in vitro activity 

K. Kaniga, K. Krause, D. Johnston, C. Lane, 

L. White, T. Wu, D.V. Debabov, J.L. Pace, 

D.L. Higgins (South San Francisco, USA) 

13:00–14:00 

Mycology 

P1763 Pneumocystis jiroveci: 

a new human saprophyte? 

F.J. Medrano, N. Respaldiza, J.M. Varela, 

A. Gasch, M.A. Montes-Cano, M.J. Pérez-Lozano, 

C. de la Horra, R. Valencia, M. Conde, E. Calderón 

(Seville, E) 

P1764 Genetic diversity of Pneumocystis jiroveci 

isolates obtained in the area of Seville, Spain 

F.J. Medrano, M.A. Montes-Cano, J.M Varela, 

N. Respaldiza, C. de la Horra, J. Martín-Juan, 

R. Torronteras, I. Mateos, E. Calderón (Seville, E) 

P1765 Pneumocystis jiroveci colonization in lung 

transplantation receptors with cystic fibrosis 

F.J. Medrano, F.J. Dapena, M.A. Montes-Cano, 

J.M. Varela, N. Respaldiza, C. de la Horra, 

D. González-Jiménez, E. Calderón (Seville, E) 

P1766 Genotypic resistance to sulfa drugs in 

patients with Pneumocystis pneumonia 

in southern Spain 

F.J. Medrano, C. de la Horra, M.A. Montes-Cano, 

N. Respaldiza, J.M. Varela, I. Mateos, J. Martín- 

Juan, R. Torronteras, R. García-Contreras, 

E. Calderón (Seville, E) 

P1767 Quantitative real-time PCR TaqMan assay for 

detection of Pneumocystis jiroveci 

F. Brancart, H. Rodriguez-Villalobos, P.A. Fonteyne, 

D. Peres Bota, D. Swinne, N. Nolard, C. Liesnard 

(Brussels, B) 

P1768 Susceptibility profile of medically relevant 

Basidiomycota species other than 

Cryptococcus neoformans 

M. Cuenca-Estrella, A. Gomez-Lopez, E. Mellado, 

V. Parra, J.L. Rodriguez-Tudela (Majadahonda, E) 


P1769 Investigation of Pal's agar to detect in vitro 

phenoloxidase activity of Cryptococcus 

neoformans strains and to differentiate 

C. neoformans from Candida albicans 

A.S. Kantarcioglu, A. Yucel, V. Vidotto 

(Istanbul, TR; Turin, I) 

P1770 Cryptococcosis in non-HIV-infected patients: 

a report of 29 cases 

S. Kiertiburanakul, S. Wirojtananugoon, 

R. Pracharktam, S. Sungkanuparph (Bangkok, TH) 

P1771 In vivo interaction of flucytosine in 

combination with amphotericin B against 

flucytosine-resistant and flucytosine - 

susceptible Cryptococcus neoformans clinical 

isolates 

P. Schwarz, F. Dromer, O. Lortholary, E. Dannaoui 

(Paris, F) 

P1772 In vitro interaction of flucytosine in 

combination with amphotericin B against 

flucytosine-resistant Cryptococcus 

neoformans clinical isolates 

P. Schwarz, F. Dromer, O. Lortholary, E. Dannaoui 

(Paris, F) 

P1773 First isolation of Sporopachydermia cereana 

in humans 

P.-M. Rath, A. Haas, B. Grabein, H. Dermoumi 

(Essen, Munich, D) 

P1774 Outcome of fungal peritonitis in patients on 

continuous ambulatory peritoneal dialysis: 

analysis of an 11-year experience in a single 

centre 

C.P.K. Subudhi, T. Ledson, K.S. Raman, 

S. Waldek, P.R. Chadwick (Salford, UK) 

P1775 Fusarium fungaemia in four Danish 

haematological patients 

T.G. Jensen, B. Gahrn-Hansen, M. Arendrup, 

B. Bruun (Odense, Copenhagen, Hillerød, DK) 

P1776 The aetiologic agents of onychomycosis in 

Latvia 

E. Lavrinovica, I. Jakobsone, I. Briede, J. Kroica 

(Riga, LV) 

P1777 Rapid identification of opportunistic fungi 

with generic PCR and pyrosequencing 

V. Fernandez, M. Krabbe, E. Jakobsson, 

P. Hagblom (Solna, Uppsala, S) 

P1778 Cyclic peptides and depsipeptides: 

markers of fungal infections 

A. Jegorov, M. Sulc, A. Ulrych, P. Navratil, 

V. Curn, B. Kratochvil, V. Havlicek 

(Ceske Budejovice, Prague, Hradec Kralove, CZ)


P1779 Identification and characterisation of clinical 

isolates of Trichosporon species from Kuwait 

S. Ahmad, M. Al-Mahmeed, Za. Khan, Zi. Khan 

(Safat, KWT) 

P1780 Phylogenetic positions of clinical isolates 

within the filamentous fungal genus 

Trichoderma 

L. Kredics, Z. Antal, A. Szekeres, M. Láday, 

I. Dóczi, J. Varga, L. Manczinger, E. Nagy 

(Szeged, Budapest, HUN) 

P1781 Growth of Aspergillus fumigatus is inhibited 

by Candida species on sealed Sabouraud agar 

plates, but not on sealed Columbia agar 

plates 

A. Becker, N. Akkad, D.H. Forster, E. Kniehl 

(Karlsruhe, D) 

P1782 Phenotyping by Fourier-transform infrared 

spectroscopy versus restriction- and 

amplification-based genotyping of Candida 

tropicalis isolates: a comparison 

A.S. Al Masri, F. Kipp, H.C. Gugnani, W. Fegeler, 

K. Becker (Munster, D; Delhi, IND) 

P1783 Development of a lovastatin resistance-based 

transformation system for Rhizomucor miehei 

C. Vagvolgyi, G. Lukacs, I. Nyilasi, T. Papp 

(Szeged, HUN) 

P1784 Identification of Rhizomucor species by 

means of biochemical and molecular methods 

T. Papp, G. Lukacs, M. Vastag, C. Vagvolgyi, 

E. Nagy (Szeged, HUN) 

P1785 In vitro antifungal activity, cytotoxicity and 

cellular accumulation of new water-soluble 

amphotericin B – polyvinylpyrrolidone 

formulations 

E. Charvalos, M.N. Tzatzarakis, F. Van Bambeke, 

P.M. Tulkens, A.M. Tsatsakis, M.-P. Mingeot- 

Leclercq (Athens, Crete, GR; Brussels, B) 

P1786 Two cases of severe phototoxic reactions 

related to long-term outpatient voriconazole 

treatment 

S.J. Vandecasteele, E. Van Wijngaerden, 

W.E. Peetermans (Leuven, B) 

P1787 Outcome and aqueous drug levels of 

voriconazole in four patients with fungal 

keratitis treated with voriconazole 

A. Zinkernagel, M. Scherrer, J. Burhenne, 

W.E. Haefeli, M. Thiel (Zurich, CH; Heidelberg, D) 

P1788 Voriconazole for the treatment of drugresistant 

fungal infections: experience from 

a Compassionate-Use Program in Spain 

J.M. Aguado, J.M. Cisneros on behalf of Spanish 

Group of Voriconazole Study 

P1789 Lack of hepatic effect of anidulafungin 

D. Krause, J Schranz, W. Birmingham 

(King of Prussia, USA) 

P1790 Ex vivo combined activity of posaconazole 

and granulocyte-macrophage colonystimulating 

factor-treated neutrophils against 

Scedosporium prolificans 

M. Simitsopoulou, C. Gil-Lamaignere, 

L. Kourounaki, D. Loebenberg, E. Roilides 

(Thessalonica, GR; Kenilworth, USA) 

P1791 Posaconazole as salvage therapy for 

Pseudallescheria infections: a case series 

R. Hachem, J.R. Graybill, R. Negroni, 

K. Presberg, G. Schiller, P. Zakowski, L. Pedicone 

(Houston, San Antonio, USA; Buenos Aires, 

AR; Milwaukee, Los Angeles, Kenilworth, USA) 

13:00–14:00 

Progress in pharmacokinetics and 

pharmacodynamics – II 

P1792 Serum protein binding of erythromycin as 

measured by ultrafiltration, dialysis filtration 

and ultracentrifugation 

A. Sandberg, H.U. Nielsen, O. Cars, 

M. Christiansen, N. Frimodt-Møller 

(Copenhagen, DK; Uppsala, S) 

P1793 Pharmacokinetics of moxifloxacin in patients 

undergoing continuous ambulatory peritoneal 

dialysis 

C. Skalioti, T. Tsaganos, M. Raftogiannis, 

D. Plachouras, H. Giamarellou, 

E.J. Giamarellos-Bourboulis (Athens, GR) 

P1794 An oral regimen to achieve steady serum 

levels of levofloxacin in patients undergoing 

hemofiltration 

P. Kouki, T. Tsaganos, M. Raftogiannis, P. Digenis, 

H. Giamarellou, E.J. Giamarellos-Bourboulis 

(Athens, GR) 

P1795 Multiple-dose pharmacokinetics of linezolid 

during continuous venovenous hemofiltration 

B. Meyer, G. Kornek, M. Nikfardjam, G. Delle Karth, 

G. Heinz, G. Locker, W. Jaeger, F. Thalhammer 

(Vienna, A) 

P1796 The breakpoint index – a new pharmaco - 

dynamic parameter for assessing antibiotic 

combinations 

I.M. Gould, K. Milne, F.M. MacKenzie 



page 141


P1797 Influence of protein binding on the activity 

of beta-lactam antibiotics on Haemophilus 

influenzae 

C. Fuhst, A. Barger, B. Wiedemann (Bonn, D) 

P1798 PK/ PD Indices: good predictors for highly 

protein bound drugs? 

C. Fuhst, A. Barger, B. Wiedemann (Bonn, D) 

P1799 A new pharmacokinetic/pharmacodynamic 

model to characterise the antibacterial effect 

of antibiotics against Escherichia coli 

A. Barger, C. Fuhst, B. Wiedemann, W. Alt, 

J. Kreft (Bonn, D) 

P1800 Interaction of bacterial inoculum, strain mic 

and drug formulation on the antibacterial 

effect of co-amoxiclav on penicillin-resistant 

S. pneumoniae 

K. Bowker, A. Noel, A. MacGowan, C. Rogers 

(Bristol, UK) 

P1801 High frequency of adverse effects to anti - 

biotics in cystic fibrosis patients and fast 

protocol of intravenous desensitization 

S. Farina, G. Taccetti, T. Repetto, E. Novembre, 

R. Bernardini, S. Campana, F. Festini, N. Ravenni, 

G. Mergni, M. de Martino (Florence, I) 

P1802 Pharmacokinetics of gentacoll investigated by 

in vivo microdialysis 

L. Stolle, M. Arpi, P. Holmberg-Jorgensen, 

J. Keller, P. Riegels-Nielsen (Aarhus, Esbjerg, DK) 

P1803 Pharmacodynamics of levofloxacin (usual 

and high dose) and moxifloxacin versus 

Streptococcus pneumoniae from the SENTRY 

antimicrobial surveillance program 

(2002–2003) in elderly patients using 

Monte Carlo Analysis and population 

pharmacokinetics 

R.C. Owens Jr., R. Jones 

(Portland, North Liberty, USA) 

P1804 Pharmacokinetics and pharmacodynamics 

of ciprofloxacin in relation to the mutant 

prevention concentration for E. coli 

S. Olofsson, D. Hughes, O. Cars (Uppsala, S) 

P1805 Pharmacodynamics of levofloxacin-imipenem 

combination against mutants of Pseudomonas 

aeruginosa resistant to one or both drugs 

P. Lister, D. Wolter, P. Wickman, M. Reisbig 

(Omaha, USA) 


P1806 Concentrations in plasma and urinary 

excretion of ciprofloxacin XR (1000 mg) 

versus levofloxacin (500 mg) in healthy 

volunteers receiving a single oral dose 

F.M.E. Wagenlehner, U. Tischmeyer, 

M. Kinzig-Schippers, C. Wagenlehner, F. Sörgel, 

K.G. Naber (Straubing, Nuremberg-Heroldsberg, D) 

P1807 Failure to detect emergence of resistance 

to moxifloxacin at AUC/MIC ratios between 

9-216 in Bacteroides fragilis, Clostridium 

perfringens and Gram-positive anaerobic 

cocci in an in vitro pharmacokinetic model 

K. Bowker, A. Noel, A. MacGowan (Bristol, UK) 

P1808 Prevention of resistance development 

with levofloxacin in epithelial lining fluid 

demonstrated by simulation of the 

concentration time curves in an in vitro model 

B. Wiedemann, M. Kresken, S. Bagel (Bonn, D) 

P1809 Use of an in vitro pharmacodynamic model 

and Monte Carlo simulation to characterise 

the pharmacokinetics and pharmacodynamics 

of gatifloxacin vs Salmonella typhi 

B.M. Booker, P.F. Smith, A. Forrest, J. Bullock, 

P. Kelchlin, S.M. Bhavnani, P.G. Ambrose 

(Buffalo, USA) 

P1810 Bactericidal activities of moxifloxacin in 

comparison to other substances used for the 

oral treatment of pulmonary infections 

S. Schubert, U. Ullmann, A. Dalhoff 

(Kiel, Germany, Leverkusen, D) 

P1811 Pharmacodynamic studies of amoxicillin in an 

in vitro kinetic model against Streptococcus 

pneumoniae with different susceptibilities 

to amoxicillin: a comparison of different 

dosage regimens including a new pharmacokinetically 

enhanced formulation 

I. Odenholt, O. Cars, E. Löwdin (Malmö, Uppsala, S) 

P1812 Strain-independent ratios of the 24-h area 

under the curve to MIC of moxifloxacin 

associating with the emergence of 

Streptococcus pneumoniae resistance: 

related changes in susceptibility and 

resistance frequency in an in vitro dynamic 

model 

S. Zinner, D. Gilbert, K. Simmons, I. Lubenko, 

A. Firsov 

(Cambridge, Providence, USA; Moscow, RUS) 

P1813 Pharmacodynamic activity of fluoroquinolones 

on different genotypes of 

Escherichia coli 

A. Carricajo, A. Texier, N. Fonsale, A.C. Vautrin, 

G. Aubert (Saint-Etienne, F)


P1814 Bone and serum concentrations of 

moxifloxacin in patients undergoing knee 

arthroplasty 

L. Malincarne, M. Ghebregzabher, M.V. Moretti, 

G. Tavolieri, D. Francisci, G. Stagni, G. Cerulli, 

F. Baldelli (Perugia, I) 

P1815 Evaluation of the antibacterial activity of 

moxifloxacin vs gatifloxacin vs levofloxacin 

in serum and target tissues using in vitro and 

in silico PK/PD modelling 

H. Stass, S. Schubert, L. Kieselbach, A. Dalhoff 

(Wuppertal, Kiel, D) 

P1816 Population PK/PD analysis for moxifloxacin 

400 mg once-daily to treat Streptococcus 

pneumoniae infections 

H. Stass (Wuppertal, D) 

P1817 Pharmacodynamics of moxifloxacin in 

combination with ceftazidime of P. aeruginosa 

A. Dalhoff, I. Schneider, A. Bauernfeind 

(Wuppertal, Munich, D) 

P1818 Comparative levofloxacin and ciprofloxacin 

mutant prevention concentrations in 

Pseudomonas aeruginosa populations from 

cystic fibrosis and ICU patients 

M. García Castillo, M.I. Morosini, M.R. Baquero, 

A. Oliver, F. Baquero, R. Cantón 

(Madrid, Palma de Mallorca, E) 

P1819 Comparative pharmacodynamics of 

telithromycin and clarithromycin against 

differentially susceptible Streptococcus 

pneumoniae in an in vitro dynamic model 

I. Alferova, I. Lubenko, S. Zinner, A. Firsov 

(Moscow, RUS; Cambridge, USA) 

P1820 Bactericidal activity and postantibiotic effects 

of clarithromycin against Streptococcus 

pneumoniae with the efflux mechanism of 

macrolide resistance 

T. Horvat, F. Warkentine, Y. Li (Kansas City, USA) 

13:00–14:00 

Molecular bacteriology: streptococcus, 

meningococcus and haemophilus 

P1821 Cpn60 gene based PCR identification of 

streptococcal species 

A. Dmitriev, L. Tkacikova, I. Mikula 

(Saint-Petersburg, RUS; Kosice, SK) 

P1822 Molecular epidemiology of nasopharyngeal 

penicillin-non-susceptible Streptococcus 

pneumoniae isolated from children in 

day-care centres and orphanages in Russia 

(SPARS study) 

I.S. Palagin, R.S. Kozlov, A.D. Narezkina, 

M.V. Edelstein, L.S. Stratchounski (Smolensk, RUS) 

P1823 Heterogeneity of PavA fibronectin-binding 

protein in Streptococcus pneumoniae 

N. Virgincar, J. Leeming, H. Jenkinson, 

R. Heyderman (Bristol, UK) 

P1824 Evaluation of a LightCycler PCR assay for 

detection of group B streptococcus in 

pregnant women with rupture of membranes 

at term 

R.P. Spence, K. Levi, K.J. Towner 

(Nottingham, UK) 

P1825 A PCR-RFLP assay for detection of parC, and 

gyrA mutations in fluoroquinolone-resistant 

Streptococcus pyogenes 

R. Alonso, M. Galimand, R. Cisterna, P. Courvalin 

(Vitoria-Gasteiz, E; Paris, F; Bilbao, E) 

P1826 Cloning and expression of Group B streptococcal 

gene – analogue of the streptococcal 

adherence related lipoproteins 

E. Vorobieva, A. Suvorov (St.Petersburg, RUS) 

P1827 The relationship between the modular 

structure of eukaryotic-like serine/threonine 

protein kinase StkP of Streptococcus 

pneumoniae and its function 

P. Pallova, L. Prenosilova, L. Novakova, P. Branny 

(Prague, CZ) 

P1828 Identification of streptococci to the species 

level by pyrosequencing 

M. Haanperä, P. Huovinen, J. Jalava 

(TURKU, FIN) 

P1829 Multi-locus sequence typing of group A 

streptococci from a London hospital 

K. McGregor, B. Spratt (London, UK) 

P1830 Microarray-based identification of genes and 

2-D gel analysis of proteins regulated by 

Ser/Thr protein kinase of Streptococcus 

pneumoniae 

L. Prenosilova, L. Novakova, P. Branny (Prague, CZ) 


page 143


P1831 Rapid identification of Streptococcus spp. by 

Pyrosequencing analysis of the rnpB gene 

Å. Innings, B. Herrmann, J. Täpp, M. Thollesson, 

M. Krabbe (Uppsala, S) 

P1832 Multilocus sequence typing of Neisseria 

meningitidis directly from cerebrospinal fluid 

J. Kalmusova, P. Kriz, R. Haugvicova, J. Felsberg 

(Prague, CZ) 

P1833 Clonal distribution of Czech invasive Neisseria 

meningitidis isolates 

M. Musilek, P. Kriz, J. Kalmusova, R. Haugvicova, 

J. Felsberg (Prague, CZ) 

P1834 Correlation of the latex agglutination and 

the PCR method in patients with invasive 

meningococcal disease 

E. Bronska, V. Maresova, P. Kriz, J. Kalmusova, 

O. Dzupova (Prague, CZ) 

P1835 Design and evaluation of a CustomSeq 

microarray for genotypic characterisation 

of Neisseria meningitidis 

C. Corless, J. Prosser, R. Borrow, E. Kaczmarski, 

M. Guiver (Manchester, High Wycombe, UK) 

P1836 Recent emergence of a virulent clone of 

Neisseria meningitidis C:2b:P1.5 with 

decreased susceptibility to penicillin in Italy 

P. Stefanelli, C. Fazio, A. Neri, T. Sofia, 

P. Mastrantonio (Rome, I) 

P1837 Molecular characterisation by PFGE of 

phenotypically indistinguishable Neisseria 

meningitidis stains 

M.J. Simões, L. Brum on behalf of the Laboratory 

Meningococcal Disease Network (Lisbon, P) 

P1838 Application of real-time PCR to Meningococcus 

detection in formaline-fixed tissues 

A. Fernández-Rodríguez, R. Álvarez-Lafuente, 

B. Aguilera, M.P. Suárez-Mier, J.A. Vázquez, 

G. Vallejo, J. Gómez (Madrid, E) 

P1839 Amplification of capsule b locus in invasive 

H. influenzae strains isolated from children 

with Hib conjugate vaccine failures 

M. Cerquetti, R. Cardines, M. Ciofi degli Atti, 

M. Giufrè, P. Mastrantonio, M. Slack 

(Rome, I; Oxford, UK) 

P1840 Comparison of conventional culture and PCR 

techniques in detection of Haemophilus 

influenzae in cerebrospinal fluids and middle 

ear effusions 

I. Jbara, M. Baysallar, S. Yetiser, B. Unay, 



13:00–14:00 

Emerging infectious diseases 

P1841 A prospective multicentre study on 

community-acquired pneumonia in the postoutbreak 

period of SARS in South Korea: 

a role of atypical pathogens including SARS- 

CoV 

J.W. Sohn, M.J. Kim, Y.H. Choi, H.J. Lee, 

H. Chun, H.S. Shim, E.J. Choi, S.C. Park 

(Seoul, Suwon-si, Kyunggi-do, KOR) 

P1842 Detection of SARS-CoV by oligochromato - 

graphy of RT-PCR amplicons 

P. Mertens, L. Vijgen, C. Olungu, S. Degallaix, 

I. Renuart, M. Van Ranst, T. Leclipteux 

(Gembloux, Leuven, B) 

P1843 Experience in PCR diagnosis of SARS 

coronavirus in Taiwan 

J.J. Lu, C.L. Perng, T.S. Chiueh (Taipei, TW) 

P1844 Study of Q-fever on the territory of the 

Republic of Moldova 

I. Uspenskaia, A. Movila, V. Chicu, A. Gutsu, 

J. Konovalov, V. Melnic, E. Kulibacnaia 

(Kishinev, MD) 

P1845 Human granulocytic ehrlichiosis in Austria: 

epidemiological, clinical and laboratory 

findings in four patients 

G. Walder, R. Hartl, B. Falkensammer, 

M.P. Dierich, R. Würzner (Innsbruck, A) 

P1846 Bartonella infections in the British Isles: 

review of seven years of diagnostic testing 

N. Doshi, H. Ford, T. Stocki, J. Duncan, N. Fry, 

T.G. Harrison (London, UK) 

P1847 Weil’s disease in Northern Greece. 

Correlations between clinicoepidemiological 

aspects and laboratory parameters in 

88 patients 

E. Vasileiadou, M. Soubourou, M. Sidiropoulou, 

D. Chrysagis, F. Kamaria, P. Mamasi, 

D. Kolokotroni, A. Papachristou (Thessalonica, GR) 

P1848 Tick-borne pathogens in Danish roe deer 

S. Skarphedinsson, B. Lyholm, P.M. Jensen, 

K. Kristiansen (Odense, Copenhagen, Rönne, DK) 

P1849 Rapid PCR-based method for detection of 

orthopoxviruses and of other viruses 

important for differential diagnosis of 

smallpox 

F. Carletti, A. Di Caro, A. Grolla, M. Czub, 

N. Petrosillo, G. Ippolito, M.R. Capobianchi 

(Rome, I; Winnipeg, CAN)


P1850 Prevalance and impact of human meta 

pneumo virus among children and immunocompromised 

patients 

M. Raza, A. Chawla, E. Hainsworth, M. Potter, 

W. Labbett, P. Griffiths, M. Zambon, A. Geretti 

(London, UK) 

P1851 Isolation and characterisation of spotted fever 

group Rickettsiae in Taiwan 

D.-D. Ji, P.-Y. Tsui, Y.-T. Liu, M.-H. Weng, 

J.-C. Lien, P.-R. Lin, M.-F. Shaio 

(Sanhsia, Taipei, Taichung, TW) 

P1852 Fluoroquinolones versus macrolides in the 

treatment of Legionnaires’ disease 

M.L. Pedro-Botet, J. Gomez, J. Roig, Z. Vilaseca, 

N. Sopena, O. Sarroca, A. García Cruz, S. Ragull, 

M. García Núñez, C. Rey-Joly, M. Sabrià 

(Badalona, Murcia, E; Escaldes, AND) 

P1853 The characteristics of Crimean Congo 

haemorrhagic fever in a recent outbreak in 

Turkey and the impact of oral ribavirin 

therapy 

O. Ergonul, A. Celikbas, B. Dokuzoguz, S. Eren, 

N. Baykam, H. Esener (Ankara, TR) 

P1854 Phenotypic characters of S. aureus strains 

associated with 79 cases of toxic shock 

syndrome in the Czech Republic 

P. Petras (Prague, CZ) 

P1855 The recognition of two tentative novel 

species among haemolytic Acinetobacter 

strains 

A. Nemec, L. Dijkshoorn, T.J.K. van der Reijden, 

T. De Baere, P.J. van den Broek, M. Vaneechoutte 

(Prague, CZ; Leiden, NL; Ghent, B) 

P1856 First Austrian case of a severe infection with 

a sorbitol-fermenting, shiga toxin-producing 

E. coli O157 and first case of a documented 

transmission of such a strain by animal 

contact 

D. Orth, K. Grif, M. Dierich, R. Würzner 

(Innsbruck, A) 

P1857 The molecular epidemiology of selected 

food-borne pathogens recovered from 

paediatric patients, indigenous peoples, 

and food animals in northern Thailand 

R. Hanson, J. Kaneene, P. Padungtod, 

K. Van Maele, K. Lewiston, R. Batizy 

(East Lansing, USA; Chiang Mai, TH) 

P1858 Chlamydia pneumoniae infection in carotid 

artery disease patients and its clinical impact 

J. Niedzwiadek, E. Mazur, M.A. Wolski, 

M. Koziol-Montewka (Lublin, PL) 

P1859 Extraintestinal salmonelosis 

M. Jovanovic, S. Pavic, G. Kovacevic, 

V. Vasiljevic, G. Lazarevic (Belgrade, Uzice, CS) 

P1861 Meningococcal carriage in an urban 

population in Burkina Faso in 2003 

J.E. Mueller, S. Yaro, L. Sangaré, Z. Tarnagda, 

A. Drabo, Y. Traoré, B. Lafourcade, B. Gessner 

(Paris, F; Bobo-Dioulasso, Ouagadougou, BF) 

13:00–14:00 

ESBL and metallo-beta-lactamases – II 

P1862 Evaluation of extended-spectrum betalactamase 

among K. pneumoniae and its 

susceptibility pattern among infection 

isolates from a university hospital in 

São Paulo, Brazil 

F. Rossi, M.N. Burattini, R. Arruda, D. Andreazzi, 

C. Bento, S. Freitas, G. Almeida (São Paulo, BR) 

P1863 Risk factors for acquisition of carbapenemresistant 

Klebsiella pneumoniae among 

hospitalised patients 

I.-G. Bae, Y.G. Kwak, E.J. Choo, S. Choi, 

J. Chung, Y.S. Kim, N.J. Kim, J. Ryu 

(Jinju, Seoul, KOR) 

P1864 Incidence rate and detection of Klebsiella 

pneumoniae producing extended-spectrum 

beta-lactamase in a department of 

anesthesiology and resuscitation, Ceske 

Budejovice 

M. Hornikova, M. Balejova, M. Hynkova, 

P. Kucerova (Ceske Budejovice, CZ) 

P1865 Extended-spectrum beta-lactamases in 

Klebsiella pneumoniae isolates from a Madrid 

hospital: an updated complex situation 

(2001 to 2003) 

A. Valverde, T.M. Coque, N. Nattell, A. Novais, 

A. Rollán, F. Baquero, R. Cantón (Madrid, E) 

P1866 The occurrence and relatedness of extendedspectrum 

beta-lactamases among 

Enterobacter spp. isolates in Tel Aviv 

J. Schlesinger, S. Navon-Venezia, I. Chelminitzki, 

O. Hammer-Muntz, M. Schwaber, Y. Carmeli 

(Tel Aviv, IL) 


page 145


P1867 Outbreaks of SHV and CTX-M co-producing 

Enterobacter cloacae in the intensive care 

unit of a Belgian hospital 

J. Frankard, R. Li, R. De Mendonça, 

H. Rodriguez-Villalobos, A. Deplano, B. Byl, 

J.-L. Vincent, M. Struelens (Brussels, B) 

P1868 The first identification of VIM-1 in an 

Enterobacter cloacae isolate from a university 

hospital in Greece 

I. Galani, M. Souli, Z. Chryssouli, K. Orlandou, 

H. Giamarellou (Chaidari, GR) 

P1869 Prevalence of extended-spectrum betalactamases 

and metallo-beta-lactamases in 

clinical isolates of Enterobacter cloacae from 

northern Italy 

F. Luzzaro, A. Endimiani, M. Perilli, C. Colinon, 

G. Celenza, G. Amicosante, G.M. Rossolini, 

A. Toniolo (Varese, L'Aquila, Siena, I) 

P1870 Drug resistance and molecular epidemiology 

of beta-lactamase-producing Enterobacter 

cloacae strains isolated from hospital and 

aquatic environments 

R. Cernat, V. Lazar, C. Balotescu, M. Nicolae, 

O. Banu (Bucharest, RO) 

P1871 Spread of OXA-23-producing Acinetobacter 

baumannii clones in England 

J.M. Coelho, N. Woodford, M. Warner, J.F. Turton, 

M.E. Kaufmann, T.L. Pitt, D.M. Livermore 

(London, UK) 

P1872 The emergence of VIM-2 in Latin American 

hospitals: report from the SENTRY 


R. Mendes, M. Guzman, P. Garcia, R. Jones, 

M. Toleman, T. Walsh, H. Sader 

(Sao Paulo, BR; Caracas, VE; Santiago, CL; 

North Liberty, USA; Bristol, UK) 

P1873 Endemic and epidemic occurrences of 

metallo-beta-lactamases in Japanese medical 

centres (1998-2002): report from the SENTRY 


R. Jones, G. Deshpande, J. Bell, J. Turnidge 

(North Liberty, USA; Alelaide, AUS) 

P1874 Resistance to imipenem and detection 

of class 1 integrons on P. aeruginosa and 

A. baumannii clinical isolates 

M.J. Canduela, E. Sevillano, F.E. Calvo, 

A. Umaran, L. Gallego (Bilbao, E) 

P1875 Metallo-beta-lactamase-mediated 

carbapenem resistance in Pseudomonas 

aeruginosa in an Indian intensive care unit 

U. Sekar, H. Latha, V. Kamat (Chennai, IND) 


P1876 Outbreak of multiresistant Pseudomonas 

aeruginosa producing the metallo betalactamase 

IMP-13 in a general intensive care 

unit in southern Italy 

R. Migliavacca, C. Colinon, J.-D. Docquier, 

M. Spalla, E. Nucleo, M. Li Bergoli, M. Labonia, 

G.M. Rossolini, L. Pagani 

(Pavia, Siena, S.Giovanni Rotondo, I) 

P1877 Characterisation of integrons carrying blaVIM 

type metallo-beta-lactamase genes from 

carbapenem-resistant Pseudomonas 

aeruginosa clinical isolates in Hungary 

B. Libisch, K. Csiszár, L. Rókusz, G. Ternák, 

M. Gacs, M. Füzi (Budapest, HUN) 

P1878 Metallo-beta-lactamase-producing Gramnegative 

bacilli in KONSAR group hospitals: 

continued prevalence of VIM-2-producing 

Pseudomonas spp. and increase of 

IMP-1-producing Acinetobacter spp. in 2002 

K. Lee, G. Ha, B. Shin, J. Kim, J. Kang, S. Jang, 

D. Yong 

(Seoul, Gyeong Ju, Inchon, Kuri, Kwangju, KOR) 

P1879 Characteristics of ESBL-producing Proteus 

mirabilis isolates in Korea 

D. Yong, Y. Lim, J. Yum, K. Lee, Y. Chong 

(Seoul, KOR) 

P1880 Clonal diversity and carbapenemase 

production in carbapenem-resistant 

Acinetobacter baumannii isolated in a 

Portuguese hospital, during a three-year 

period 

S.M. Quinteira, H. Ramos, J. Amorim, J.C. Sousa, 

L. Peixe (VN Famalicão, Porto, P) 

P1881 Communitiy-acquired urinary tract infections 

by extended-spectrum beta-lactamaseproducing 

Escherichia coli in children: 

clinical and molecular characteristics 

M.A. Lee, H.W. Moon, S.J. Lee (Seoul, KOR) 

13:00–14:00 

Susceptibility to miscellaneous antimicrobial 

agents 

P1882 Comparison of in vitro activity of gatifloxacin, 

moxifloxacin, trovafloxacin and clindamycin 

against clinically significant anaerobes 

K. Aldridge, C. Manders, S. Broyles 

(New Orleans, USA) 

P1883 Antibiotic susceptibility of bacterial strains 

isolated from community-acquired respiratory 

tract infections in Austria 2002 

S. Forsthuber, A. Buxbaum, W. Graninger, 

A. Georgopoulos (Vienna, A)


P1884 A comparison of the bactericidal activities 

of penems, a penam, a cephem and a 

fluoroquinolone against common respiratory 

tract pathogens 

U. Ullman, S. Schubert, A. Dalhoff (Kiel, D) 

P1885 Antibiotic susceptibility of isolates in the 

intensive care unit in Greece: 

three years of the Meronem Yearly 

Susceptibility Test Information Collection 

(MYSTIC) programme 

A. Gikas, J.A. Papadakis, H. Triantafyllopoulou, 

A. Christidou, A. Katsandri, D. Toffas, 

G. Petrikkos (Heraklion, Athens, GR) 

P1886 Comparative in vitro activity of ertapenem 

against respiratory pathogens circulating 

in Italy 

L. Gualco, G. Schito, A. Marchese (Genoa, I) 

P1887 In vitro activity of ertapenem in comparison 

with penicillin, piperacillin/tazobactam, 

clindamycin, and metronidazole against 

clinical isolates of anaerobic bacteria 

W. Pfister, J. Roedel, E. Straube (Jena, D) 

P1888 Is antibiotic combination more effective 

than single drug therapy in anthrax? 

A. Athamna, M. Athamna, N. abu Rashed, 

E. Shlyakov, D. Bast, E. Rubinstein 

(Kfar Qaraa, Tel Aviv, IL; Toronto, CAN) 

P1889 Combination effect of ertapenem (MK 826) 

with aminoglycosides against Gram-positive 

and Gram-negative community-acquired 

pathogens 

U. Frank, C. Wilson, E. Baumgarten, I. Engels, 

M. Dettenkofer, F. Daschner (Freiburg, D) 

P1890 QC study evaluating the performance 

of daptomycin and combination 

daptomycin/calcium disks and E-test 

L. Koeth, J. DiFranco (Westlake, USA) 

P1891 Impedimetry - test for determination 

of bactericidal activity of antiseptics 

T. Zarêba, E. Bocian, S. Tyski (Warsaw, PL) 

P1892 In vitro synergism between linezolid and UV 

radiation against biofilms of Staphylococcus 

aureus 

M. El-Azizi, N. Khardori (Springfield, USA) 

P1893 Antimicrobial activity of amniotic membrane 

soaked in antibiotics 

R. Dei, R. Mencucci (Florence, I) 

P1894 Mechanism of the inoculum effect of 

Providencia stuartii with beta-lactam 

antibiotics 

N. Khalaf, I. Wiegand, B. Wiedemann 

(Cairo, EGY; Bonn, D) 

P1895 Evaluation of the antimicrobial activity 

of chlorhexidine gluconate adjunctive 

zinc polycarboxylate cement in fixed 

prosthodontics 

B. Orug, M. Baysallar, A. Kucukkaraaslan, 

D. Cetiner, L. Doganci, B. Bal (Ankara, TR) 

P1896 Reproducibility of mycobacterial QC strains 

in the Sensititre rapid growing and slowly 

growing nontuberculosis mycobacteria broth 

microdilution susceptibility procedure 

M. Brimecombe, P. Stagg, G. Hammerton, 

S. Killian, C. Knapp, R. Grist 

(East Grinstead, UK; Cleveland, USA) 


page 147

List of Chairpersons 

Name Page Name Page Name Page 

Aires de Sousa, Marta 36 

Akova, Murat 39, 57 

Aktories, Klaus 37 

Amsden, Guy W. 47 

Appelbaum, Peter 41, 48 

Arendrup, Maiken 62 

Baughman, Robert 29 

Bébéar, Christiane 33 

Benes, Jiri 35, 38 

Beran, Jiri 40, 51 

Bille, Jacques 62 

Blasi, Francesco 47 

Bouza, Emilio 37 

Brazier, Jon 37 

Brisse, Sylvain 52 

Bronzwaer, Stef 45 

Brown, Derek 51 

Brown, Nick 36 

Calandra, Thierry 32 

Carbon, Claude 36, 44 

Carlet, Jean 41, 59 

Chalupa, Pavel 59 

Chavanet, Pascal 50 

Clementi, Massimo 39, 59 

Cockerill, Franklin R. 44 

Coockson, Barry 61 

Cornaglia, Giuseppe 37, 57 

De Pauw, Ben 55, 64 

Dellamonica, Pierre 40, 46 

Denning, David W. 47, 48, 50 

Derendorf, Hartmut 29, 61 

Drusano, George 50 

Durack, David 37 

Edwards, Jeff 35, 48 

Eggers, Maren 32 

Ellis, Michael 41 

Etienne, Jerome 37 

Evengård, Birgitta 49 

Falagas, Matthew 64 

File, Thomas M. 47 

Filip, Roxana 53 

Finch, Roger 49, 60 

Francioli, Patrick 37, 41 

Frank, Uwe 62 

French, Gary 35 

Frosch, Matthias 38 

Galsky, Jan 45 

Garau, Javier 48 

Gastmeier, Petra 45 

Glauser, Michel 29, 35, 61 


Gniadkowski, Marek 58 

Goossens, Herman 51, 59 

Gould, Ian 48, 51, 58 

Graninger, Wolfgang 38, 41 

Guzman, Maria 57, 61 

Haigh, Ronald 38 

Hatz, Christoph 32, 53 

Herbrecht, Raoul 55 

Hirsch, Hans 57 

Hirschl, Alexander 37 

Höffken, Gert 47 

Hohlfeld, Patrick 32, 49 

Høiby, Niels 62 

Hryniewiecz, Waleria 37 

Hubalek, Zdenek 49 

Ieven, Margareta 49, 57 

Ioannidis, Ioannis 39 

Jarlier, Vincent 36 

Jelinek, Tomas 57 

Jelinkova, Jarmila 37, 57 

Jindrak, Vlastimil 37, 58 

Jones, Ronald 52 

Joseph, Carol 61 

Kahlmeter, Gunnar 51, 62 

Kolarova, Libuse 32 

Kriz, Bohumir 37 

Kriz, Paula 51 

Kullberg, Bart-Jan 60 

Labuda, Milan 62 

Livermore, David 61 

Lode, Hartmut 36, 55 

Lortholary, Olivier 50 

Maertens, Johan 48, 58 

Maresova, Vilma 33, 52 

Mégraud, Francis 37, 44 

Monnet, Dominique 48 

Moreillon, Philippe 36, 38 

Mouton, Johann W. 29 

Mühlemann, Kathrin 48, 52 

Nagy, Elisabeth 44 

Niederman, Michael 55 

Niedermann, N. 36 

Nord, Carl Erik 49 

Norrby, Ragnar 37, 44 

Osterhaus, Albert 32 

Peiris, Malik 32 

Peixe, Luisa 58 

Peltola, Heikki 37 

Petrovec, M. 39 

Phillips, Ian 35 

Potter, Michael 35 

Power, Eddie 60 

Prusova, Dagmar 38 

Ravn, Pernille 63 

Rodier, Guénaël 46 

Rodriguez-Tudela, Juan Luis 62 

Rozgonyi, Ferenc 62 

Rubinstein, Ethan 32, 61 

Rüsch-Gerdes, Sabine 55 

Sauer, Sascha 44 

Schalén, Claes 51 

Scharfen, Josef 63 

Schmid, George 50 

Schwenk, Achim 39 

Sears, Cynthia L. 44 

Siddiqi, Saman 55 

Snydman, David R. 49 

Sobel, Jack 60 

Stanek, Gerold 51 

Stankova, Marie 39 

Stratchounski, Leonid 41, 45, 48 

Stray-Pedersen, Babill 32 

Struelens, Marc 31, 44, 49 

Telenti, Amalio 39 

Toman, Rudolf 39 

Torres, Antonio 47 

Towner, Kevin 36, 49 

Tulkens, Paul 61 

Urbásˇková, Pavla 44 

Vaheri, Antti 49, 62 

Vanderbrouke-Grauls, Christina 48 

van Belkum, Alex 33, 58 

van Burik, Jo-Anne 47 

van Loon, Anton 57, 61 

Vila, Jordi 39, 49 

Vincent, Jean Louis 32 

Voss, Andreas 37, 49 

Votava, Miroslav 50, 62 

Woodhead, Mark 48, 49 

Yeni, Patrick 32 

Zanetti, Giorgio 33, 48 

Zeuzem, Stefan 39

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Aanastasakou, E. P1275 

Abanades, M.S. P1011 

Abbadi, S. P1294 

Abbate, I. O357 

Abd, H. P616 

Abdellatif, S. P625 

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Abmed, D. O302 

Abram, M. P520 

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Achour, W. P680 

Achtman, M. T1, K169, E321 

Acosta, F. P896 

Adametz, H. P1355 

Adamis, T. P906 

Adamson, V. P504, P1193 

Adlan, A. P1055 

Afhami, S. P887 

Afset, J. P690 

Agacfidan, A. P1585 

Agafonov, A.P. P1228 

Agalar, C. P1690 

Agalar, F. P1690 

Agathocleous, X. P1311 

Ager, S. O352 

Agmon, Y. P1350 

Ago, K. P958 

Agreda, M. P1455 

Aguado, J. P1446 

Aguado, J.M. P1788 

Aguilar, D. P1565 

Aguilar, J. P1678 

Aguilar, L.O200, P524, P525, P895, 

P1091, P1135 

Aguilar, M. P902 

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Aguinaga Pérez, A. P1652 

Agusti, C. O372 

Ahlem, C. O128 

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Ahmadi Ahangar, A. P470 

Ahmadnejad, F. P1243 

Ahn, J.-O. P556 

Ahuad, P. P512 

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Aisenberg, G. P1225 

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Akbulut, D. P731 

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Akhavan, P. O65 

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Akom, E. P833 

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P1011, P1717 

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Alberte, A. P1290 

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P1006, P1472, P1485 

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P1530 

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Aldridge, K.P788, P1208, P1474, 

P1882 

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P1544 

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Alexandrou, M. P1599 

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Alexanyan, T. P1147 

Alexiou-Daniel, S. P1539, P1573 

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P1227, P1749 

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P1739, P1825 

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Alvares, E. P1479 

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P1426, P1529, P1732 

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P1460, P1468, P1869 

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P1735 

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Angeletti, C. P465 

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Anoro, E. P1165 

Anselmo, M. P1565 

Anson, J. O145 

Antachopoulos, C. P1184, P1302 

Antal, Z. P1780 

Anthony, R.M. P1021 

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Antón, E. P1002 

Antonelli, M. P1541 

Antoniadou, A. O210 

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Antonios, V. P1286 

Antonopoulou, A. P1335 

Antonucci, G. O357, P674 

Antunes, F. P664 

Antunes, P. P764, P765 

Anvari Tafti, M.H. P599 

Aoun, M. P1501 

Apostolou, I. P1419 

Appel, K. P829 

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P915, P916, P919, P920, P1740, 

P1017, P1143, P1146 

Appleton, B. P552 

Aragón, L. O146 

Arancia, G. P1340 

Araújo, M.R. P1563 


Araújo, R. O401 

Arbilia, S. P1142 

Arca, E. P1483 

Archakov, A.I. P649 

Archambaud, M.P1115, P1357, 

P1426 

Archibusacci, C. P1128 

Archontidou, E. P1383 

Arcos, V. P1320, P1321 

Arda, B. P570, P1398 

Ardehali, S. P627 

Arena, A. P1317 

Arendrup, M. P1775 

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Arias-Lopez, S. P1369 

Arista, S. P1238 

Ariza, J. P908 

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Arlukowicz, E. P1016, P1665 

Armanet, M. P591 

Armanino, R. P480 

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Armillotta, G. P904 

Arnold, C. P700, P738 

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Arosio, M. P1577 

Arpi, M. P1802 

Arroyo, E. P645, P988, P1709 

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Arroyo, M. P1738 

Arruda, R. P1862 

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P1221, P1660, P1713, P1747 

Arslan, U. P615 

Arsovic, N. P998 

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Arvanitis, D. P624, P721 

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Aspiroz, C. P811 

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Ataman Hatipoglu, C. P475 

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Athamna, A. P740, P1888 

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Atrasheuskaya, A.V. P1228 

Attili, A. P816 

Aubert, A. O99 

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Augustynowicz, E. P1056 

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P1320, P1321, P1430 

page 149



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Averchenkov, V.M. O253 

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page 151



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Croos-Dabrera, R. P449 

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page 155



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page 157



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page 159



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page 163



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page 167



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Zoccoli, C. P1153, P1309 

Zolldann, D. P1399 

Zoranic, V. P1666 

Zorbas, G. P876, P1400 

Zore, A. P976 

Zorman, T. P778 

Zoubkov, M. P1592 

Zouiten, F. P1507 

Zoumberi, M. P1442 

Zozo, N. P772 

Zucca, M. P729 

Zuckerman, M. O421 

Zvizdic, A. P1370 

Zwart, S. O289 

Zweigner, J. P1050 

page 169

Abstract Book 

General Information (in alphabetical order) 

All accepted abstracts as well as abstracts of 

invited speakers (where available) have been 

published in the Abstract Book, which is a 

supplement to the journal Clinical Microbiology 

and Infection (CMI), the official journal of 

ESCMID. You will find a copy in your congress 

bag. 

Badges 

Access to all scientific events and to the 

exhibits is only possible with your personal 

badge, which you will receive upon 

registration. All participants are requested 

to wear their name badge throughout the 

congress. € 30 will be charged for replacement 

of a lost badge. From May 1–4, all participants 

will be able to use the Prague metro free of 

charge by showing their congress badge. 

Cloakroom / Left Luggage 

A cloakroom is available on the ground floor 

next to registration area to keep your coats 

and bags. 

CME Credits 

The European Society of Clinical Microbiology 

and Infectious Diseases (ESCMID) is seeking 

accreditation by the European Accreditation 

Council for Continuing Medical Education 

(EACCME) to provide CME credits for medical 

specialists. The EACCME is an institution of 

the European Union of Medical Specialists 

(UEMS, www.uems.be). EACCME credits are 

recognised as Physician’s Recognition Award 

by the American Medical Association. 

A form for claiming CME credits will be inserted 

in your congress bag. 

Currency 

All official congress prices are indicated in 

Euro (€). The official currency in the Czech 

Republic, however, is the Czech Crown (Kc). 

All major credit cards are accepted in most 

hotels, restaurants and shops. 

Electricity 

The electrical power supply in the Czech 

Republic is 220 volts. 


ESCMID booth 

During the congress, ESCMID staff will be 

happy to answer your questions at the 

ESCMID booth and help you with any 

matters concerning the Society. The ESCMID 

booth is located in the exhibition area on the 

1 st floor. 

European Network Corner 

Right next to the ESCMID booth, you will find 

the European Network Corner. The 12 ESCMID 

Study Groups and EUCAST, as well as related 

organisations like EARSS and ESAC will be 

present with a poster and staff to inform 

about their activities. Learn about and discuss 

the various activities of the Society and meet 

members of the Executive. 

Exhibition 

During the congress an industrial exhibition 

will be arranged. Companies from all over 

the world will be given ample opportunity 

to display their latest products, services and 

technical innovations. The exhibition will be 

located in the foyers of the Prague Congress 

Centre (PCC) on the first, second and third 

floor, in close proximity to all the lecture halls, 

catering and poster areas. 

The opening hours are as follows: 

Saturday, May 1 13:00–21:00 

Sunday, May 2 08:00–18:00 

Monday, May 3 09:00–18:00 

Tuesday, May 4 09:00–14:00 

Hotel Accommodation 

14 th ECCMID 2004 

c/o AKM Travel 

Messeplatz 10 

P.O. Box 

CH-4016 Basel 


Phone +41 61 690 94 11 

Fax +41 61 690 94 14 

E-mail eccmid@akmtravel.ch 

AKM Travel will be present at a special desk in 

the registration area during the congress. 

Please refer to the “Hotel” counter.

Insurance 


The congress organisers cannot accept liability 

for personal injuries sustained, or for loss 

or damage of property belonging to congress 

participants (or their accompanying persons), 

either during or as a result of the congress. 

Please check the validity of your own insurance. 

Internet Corner 

Internet terminals – available for all congress 

participants – will be located in the exhibition 

area on the second floor of the PCC. 

Language 

The congress language is English. 

Simultaneous translation will not be provided. 

Message Centre 

A message centre for the collection and 

distribution of messages has been installed 

in the registration area on the ground floor. 

Numerous display terminals throughout the 

congress centre will announce the names 

of persons for whom messages have been 

received. If your name appears on the screen, 

you can either check your message right there 

or proceed to the message centre to collect it. 

Metro 

From May 1–4, delegates will be able to use 

the Prague metro free of charge by showing 

their congress badge. 

Mobile Phones 

Please be aware that mobile telephones must 

be switched off during all sessions. 

Poster Exhibition 

Please see pages 36, 48 and 61 for further 

details. 

Prague 

Prague, capital city of the Czech Republic, 

lies in the heart of Europe, neighbouring 

with Germany, Austria, Slovakia and Poland. 

This “European City of Culture” of the year 

2000 is one of the most beautiful and charming 

cities in the world. While attending the 

14 th ECCMID, make sure to find some time to 

explore the historical centre of Prague, its 

unique collection of historical monuments as 

well as the wide range of cultural attractions. 

For further information on Prague and its 

surrounding areas visit the following websites: 

www.pis.cz 

www.prague.cz 

Press 

Press representatives are kindly asked to 

register at the on-site counters where at the 

same time they will have to show their press 

identification. The press centre is located on 

the first floor of the PCC. Various information 

such as press releases and a press agenda can 

be found at www.escmid.org (“media”). 

Registration 

A congress bag including all documents 

(Final Programme, Abstract Book, name 

badge, vouchers, etc.) will be distributed 

to the registered participants during the 

following opening hours: 

Saturday, May 1 13:00–19:00 

Sunday, May 2 07:00–18:00 

Monday, May 3 07:00–18:00 

Tuesday, May 4 07:00–16:30 

The same opening hours will be applied for 

on-site registrations. Please note that on-site 

registrants cannot be guaranteed to receive 

all congress documents. 

On-site changes of name badges due to 

incorrect submission of names and/or address 

data will be charged € 10. 


page 171

Registration Fees 


as from as from 

Jan. 21 to April 2 and 

April 1, 2004 on-site 

ESCMID Member € 400 € 520 

Non-member € 530 € 650 

Non member 

incl. 2-years 

ESCMID membership € 620 € 740 

Physician / scientist in 

training (< 35 years) * € 270 € 400 

Student** € 75 € 100 

Accompanying person € 50 € 50 

* Colleagues in training, born after 

January 1, 1969 

(copy of passport obligatory) 

** Students will need to provide proof 

(written certification by head of 

department) 

The registration fee for participants includes 

a congress bag, Final Programme, Abstract 

Book, admission to all parts of the congress, 

Opening Ceremony and Welcome Reception. 

The registration fee for accompanying persons 

includes Opening Ceremony, Welcome 

Reception and access to the industrial 

exhibition. 

Responsibility 

The participant acknowledges that he/she has 

no right to lodge damage claims against the 

organisers should the holding of the congress 

be hindered or prevented by unexpected 

political or economic events or generally by 

force majeure, or should the non-appearance 

of speakers or other reasons necessitate 

programme changes. With registration, the 

participant accepts this proviso. 


Shopping 

Like other large towns, Prague is a marvellous 

shopping city! The leading souvenir is un - 

doubtedly traditional Czech cut glass and 

crystal. Prikopy or Wenceslas Square are lined 

with enticing shop windows, whereas the 

Old Town’s little winding streets will surprise 

you with a selection of antique shops full of 

unique relics of the past. 

Travel within Prague 

From May 1–4, all participants will be able 

to use the Prague metro free of charge 

by showing their congress badge. 

The Prague Congress Centre (PCC) has it's 

own metro station (“Vysehrad”, line C) and 

is located three stops south of downtown 

Prague. AAA Taxi provide excellent taxi 

service within Prague (phone no. 233113311). 

Venue 

Prague Congress Centre 

5 Kvetna 65 



Phone +420 23907 2222 

Fax +420 23907 2012 

E-mail info@kcp.cz 

www.kcp.cz 

Webcasting 

Webcast 

� 

Symposia marked with will be 

recorded. The respective webcasts will be 

available at www.escmid.org approx. 10 days 

after the congress.

List of Exhibitors (in alphabetical order) 

Floor 

161 AB Biodisk, Solna / S 2 

325 Abbott Laboratories, Chicago IL / USA 3 

315 AdvanDx, Woburn MA / USA 3 

211 AES Laboratoire, Rennes / F 2 

065 American Society for Microbiology, 

Washington DC / USA 

1 

331 Ani Labsystems, Helsinki / SF 3 

153 Applied Maths, St-Martens-Latem / B 2 

139 artus – the PCR reference, Hamburg / D 2 

143 AstraZeneca, Macclesfield / UK 2 

133 Aventis, Bridgewater NJ / USA 2 

187 BAG BiologischeAnalysensystemGmbH, 

Lich / D 

2 

233 Baxter Vaccine AG, Vienna / A 2 

241 Baxter Vaccine AG, Vienna / A 2 

101 Bayer AG / Bayer Healthcare, 

Leverkusen / D 

2 

125 Binax Inc., Portland ME / USA 2 

177 BioMérieux, Marcy-l'Etoile / F 2 

205 Bio-Rad, Marnes-la-Coquette / F 2 

333 Biotage, Uppsala / S 3 

217 Blackwell Publishing, Oxford / UK 2 

189 Cepheid SA, Maurens-Scopont / F 2 

141 Chiron, London / UK 2 

327 Dade Behring, Frankfurt am Main / D 3 

173 Diagnostic Products Corporation, 

Los Angeles CA / USA 

2 

051 ECCMID 2005 – European Congress of 

Clinical Microbiology and Infectious 

Diseases, Copenhagen/DK 

1 

185 Elsevier, London / UK 2 

050 ESCMID – European Society of Clinical 

Microbiology and Infectious Diseases, 

Basel / CH 

1 

157 Fujisawa GmbH, Munich / D 2 

121 GDM Technologies, Melbourne / AUS 2 

221 Genzyme Virotech GmbH, 

Rüsselsheim / D 2 

131 Gilead Sciences, 

Foster City CA / USA 

Floor 

2 

135 GlaxoSmithKline, Brentford / UK 2 

219 GR Micro Ltd, London / UK 2 

175 Hain Lifescience GmbH, Nehren / D 2 

077 IAPAC, Chicaco IL / USA 1 

067 International Society of Chemotherapy, 

London / UK 

1 

075 ISID, Boston MA / USA 1 

301 King Pharmaceuticals, Bristol TN / USA 3 

215 Kluwer Academic Publishers, 

Dordrecht / NL 

2 

163 Mast, Liverpool / UK 2 

245 Merck KGaA, Darmstadt / D 2 

155 Merck Sharp & Dohme, 

Whitehouse Station NJ / USA 

2 

313 NCCLS, Wayne PA / USA 3 

329 Oxoid Ltd, Basingstoke / UK 3 

137 Pfizer Inc., New York NY / USA 2 

181 Pliva Croatia Ltd, Zagreb / CRO 2 

201 Pliva-Lachema, Brno / CZ 2 

203 Sangtec Molecular Diagnostics, 

Bromma / S 

2 

171 Savyon Diagnostics Ltd, Ashdod / IL 2 

193 Science / AAAS, Cambridge / UK 2 

109 Seapro Theranostics International, 

Lelystad / NL 

2 

213 Statens Serum Institut, Copenhagen / DK 2 

123 Test-Line, Clinical Diagnostics Ltd, 

Brno / CZ 

2 

231 Trek Diagnostic Systems, 

East Grinstead / UK 

2 

311 UK Neqas, London / UK 3 

243 Vicuron Pharmaceuticals, 

King of Prussia PA / USA 

2 

105 Waters Corporation, Prague / CZ 2 

195 Wisepress Online Bookshop, London / UK 2 

303 Wyeth, Collegeville PA / USA 3 


page 173

First Floor 

Second Floor 

Exhibition Hall Plan 

ESCMID 


077

Third Floor 

Exhibition Hall Plan 


page 175

Opening Ceremony 

Social Events 

On the evening of Saturday, May 1, 2004 

(18:00) all participants, accompanying persons 

and exhibitors are invited to attend the 

Opening Ceremony in the main Auditorium. 

The ceremony will include a short performance 

by the world famous Prague Black Light 

Theatre. 

18:00 Welcome to Prague 

(short movie) 

18:10 Prof. Jarmila Jelinkova 

President, 14 th ECCMID 

18:20 Pavel Bém, M.D., PhD. 

Lord Mayor City of Prague 

18:30 Prof. Jaroslav Blahos 

President Czech Medical 

Association of Jan Evangelista 

Purkyne 

18:40 Prof. Marc Struelens 

ESCMID President 

18:50 Mr. Georgios Gouvras 

Head of Unit “Health Threats”, 

Public Health Directorate, 

European Commission 

19:00 Prague Black Light Theatre 

Performed by “Image Theatre” 


Welcome Reception 

Following the Opening Ceremony, a welcome 

cocktail will be served within the industrial 

exhibition and the various foyers of the Prague 

Congress Centre. 

Opening Ceremony and Welcome Reception 

are included in the registration fee. 

Concert 

On Monday evening, May 3, 2004, 19:30 a 

classical concert will be performed by the 

Czech National Symphony Orchestra (duration 

approx. 90 min.). The concert will take place 

in the famous Dvorak Hall of the Rudolfinum 

and will feature the overture “My Country” 

by Bedrich Smetana as well as the Symphony 

no. 9 “From the New World” by Antonin 

Dvorak. 

Tickets at a fee of € 35 may be purchased at 

the congress secretariat on the ground floor. 

Rudolfinum

Daily Tours 

An interesting choice of guided tours has 

been prepared for all delegates and 

accompanying persons. Below you will 

find the respective schedules and short 

descriptions. Please note that all tours will 

start from the Prague Congress Centre at the 

scheduled times. CZECH-IN reserves the right 

to cancel the tour should there be less than 

15 registered persons. Tour prices include 

transfer by luxury air-conditioned bus, English 

speaking guide and entrance fees. On-site 

requests for tours are welcome but cannot 

be guaranteed. Please contact the “tours” 

counter in the registration area. 

Karlovy Vary 

Karlovy Vary (Carlsbad) 

This full-day tour out of Prague will take you 

to the most famous West Bohemian spa town 

of Karlovy Vary, which was founded by the 

Bohemian King Charles IV in the 14 th century. 

You can taste the waters from the 12 curative 

thermal mineral springs, admire the beauty of 

both the historic and modern colonnades, and 

purchase some of the typical souvenirs such 

as special wafers, Moser porcelain and glass 

or the Becherovka liqueur, also known as 

the 13 th curative spring of Karlovy Vary. The 

spa of Karlovy Vary is known for treatment of 

diseases of the digestive tract as well as 

metabolic and endocrinal disorders. The tour 

includes city sightseeing and a visit to the 

Becherovka museum, where the participants 

will taste this delicious liqueur. 

Full day including lunch 

Sunday, May 2, 2004 09:00–18:00 

Price: € 101 

Grand Tour of Prague 

During this tour you will get information 

about the history of Prague, its historical 

areas and most remarkable monuments. 

The tour starts with a visit to the Prague 

Castle, the biggest castle in the world. You will 

then pass the Lesser Town, cross the worldfamous 

Charles Bridge, continue to the Old 

Town Square, pass by the Charles University – 

the eldest university north of the Alps – 

and the Estates Theatre where Mozart personally 

conducted the world premiere of his 

Don Giovanni. This amazing walking tour will 

end in front of the Old Town City Hall with its 

extraordinary astronomical clock. 

Half day 

Sunday, May 2, 2004 09:00–13:00 

Monday, May 3, 2004 13:00–17:00 

Tuesday, May 4, 2004 13:00–17:00 

Price: € 37 

Prague Boat Trip on the Vltava River 

This tour offers the opportunity to explore 

enchanted Prague from the deck of a boat. 

The river cruise allows you to discover some 

of the city’s major monuments and sights, 

such as the National Theatre, Prague Castle 

and Charles Bridge, while relaxing over dinner 

or a drink and listening to music or dancing. 

Evening tour 

(Dep. from Čechu ° v bridge at 19:00) 

Sunday, May 2, 2004 19:00–22:00 

Price: € 40 including dinner & music 

Vltava River 


page 177

Daily Tours 

Hradčany and Prague Castle 

Enjoy some magnificent views of Prague 

as the castle area is situated well above the 

city centre. Bohemian history will attract you 

on each corner. You will visit the Strahov 

Monastery, Loretta, Golden Lane and finally 

Prague Castle with St. Vitus Cathedral. Prague 

castle was established in the 9 th century. 

In the 14 th century, under the reign of 

Charles IV, it was rebuilt in the gothic style. 

The final reconstruction of the Royal Palace 

took place under the Jagellons at the end of 

the 15 th century. The castle was enlarged 

in the 16 th century, especially after a big fire 

in 1541. Our tour will end at Prague castle 

gardens. 

Half day 

Monday, May 3, 2004 09:00 – 13:00 

Price: € 39 

Karlsˇtejn Castle 

This is one of the most outstanding medieval 

castles in existence and was established by 

King Charles IV 650 years ago, as the place 

where the crown jewels and state documents 

would be kept. The castle lies 40 km west of 

Prague. 

Half day 

Monday, May 3, 2004 09:00–13:00 

Price: € 51 

Karlsˇtejn Castle 


Prague Castle 

Pilsner Brewery 

Czech Republic is world famous for its tasty 

Pilsner beer. You will have a chance to see the 

production of it during the excursion to Pilsen 

brewery and experience onsite tasting of 

golden fluid that makes the Czech Republic 

world famous. 

Half day including lunch 

Tuesday, May 4, 2004 09:00-14:00 

Price: € 67 

Jewish Town 

During this trip you’ll be given information 

about the Jewish history of Prague which can 

be traced back to the middle of the 10 th century. 

We’ll take you to the famous Jewish quarter 

where you’ll see the cemetery from the 15 th 

century, some of the six synagogues (the 

ancient Old-New Synagogue, the oldest in 

Europe; the Pinkas Synagogue; and the 

Ceremonial Hall with its collection of 

children’s art from the Terezín concentration 

camp) and the house of F. Kafka. 

Half day 

Tuesday, May 4, 2004 9:00–13:00 

Price: € 43 

If you require further information on any of 

the above tours, please contact the “tours” 

counter in the registration area.


Future ECCMIDs 

April 2–5, 2005 

Copenhagen, Denmark 

Bella Center 

Prof. Niels Høiby, 


Abstract Deadline: 

November 18, 2004 



April 1–4, 2006 

Nice, France 

Palais des Congrès 

Nice-Acropolis 

Prof. Pierre Dellamonica, 


Abstract Deadline: 

November 17, 2005 



Copenhagen, Denmark, April 2–5, 2005 

Nice, France, April 1–4, 2006 

page 179

Prague City Map & List of Hotels 

Prague City Hotels 1 Andel’s Category C 


2 

3 

4 

5 

6 

8 

9 

10 

11 

12 

13 

14 

16 

17 

20 

21 

22 

23 

24 

26 

Adria B/C 

Corinthia Tower C/B 

Corintha Panorama C/D 

Crowne Plaza C 

Diplomat C 

Four Seasons A 

Hilton A 

Holiday Inn CC C 

Ilf F 

Interconti B 

Le Palais C 

Josef D/E 

Marriott A 

Novotel Praha City D/E 

Opera E 

Parkhotel E 

Pariz A/B 

Pyramidia D/E 

Radisson A/B 

Savoy B 

26 

23 

6 

5

1 

21 

8 

Rudolfinum 

12 

14 

2 

22 

10 

Prague Congress Centre 

17 

24 

16 

4 


3 

11 

20 

13 

9 

page 181

Penetrating power 

against MRSA 

Challenging MRSA 

linezolid IV/Oral 

Legal Classification: POM. Further information is available from the Marketing Authorisation Holder: 

Pfizer Limited, Walton Oaks, Dorking Road, Tadworth, Surrey KT20 7NS. Date of Preparation: February 2004. ZYV159

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