Staxâ¢ Disposable Depth Filters - Pall Corporation (PLL)

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Seitz AKS Filter Media Macro- and mesopores can generally be regarded as the highways into the carbon particle, and are crucial for adsorption kinetics. Macropores are used for the transport, and adsorption occurs in the meso- and micropores. Small molecules, such as methylene blue, which has a molecular weight of 319.86 daltons, are mainly captured in micropores. For larger impurity molecules, other pore structures in the carbon must be available to ensure optimal adsorption. Carbon, which can capture larger molecules, tends to adsorb smaller impurities as well, whereas dedicated carbons for small molecules do not remove larger contaminants. Table 3 provides an overview of how different AKS grades may suit an application based on their general characteristics. However, due to the various factors that may affect the adsorption process, Pall recommends scaled-down testing of several Seitz AKS filter media using Pall UpScaleSM program test kits as the most reliable way. For more information please reference Pall data sheet USD 2459 or validation guide USTR 2491. Table 3: Typical Efficiency Characteristics of Seitz AKS Media Grades Typical Molecular W eight Media Grade Efficiency Characteristics of Target Contaminants AKS 1 Ultra high efficiency 400 – 1500 Daltons AKS 2 Ultra high efficiency 400 – 1000 Daltons AKS 5 High efficiency 200 – 400 Daltons AKS 6 High efficiency 400 – 1500 Daltons AKS 7 Ultra high efficiency 400 – 1500 Daltons AKS 8 High efficiency 400 – 1000 Daltons AKS 9 High efficiency 400 – 1000 Daltons 4
Technical Information Table 4: Stax AKS Capsule Configuration Codes for Different AKS Media Grades Configuration for Media Grade Media Code Stax AKS Capsule Amount of PAC Present / Stax Capsule in Kg Media Area / Stax AKS Capsule in m² AKS 1 XAK1 406 1.45 1.40 AKS 2 XAK2 406 1.45 1.40 AKS 5 XAK5 407 1.05 1.62 AKS 6 XAK6 407 1.30 1.62 AKS 7 XAK7 406 1.45 1.40 AKS 8 XAK8 407 1.30 1.62 AKS 9 XAK9 407 1.30 1.62 Table 5: Typical Ash and Endotoxin Level for Different Pall AKS Grades Typical Endotoxin Level Media Grade Typical Ash Content in % (in EU/mL) AKS 1 < 3 < 0.12 AKS 2 < 4 < 0.12 AKS 5 < 1 < 0.06 AKS 6 < 3 < 0.06 AKS 7 < 3 < 0.12 AKS 8 < 2 < 0.12 AKS 9 < 2 < 0.12 Table 6: Dimensions and Weight of Stax AKS Capsules Capsule Footprint Capsule Weight Capsule Size Diameter Height Dry Wet* Large 442 mm 128.8 mm 7-7.5 Kg < 13 Kg (17.4 in.) (5.1 in.) * Post blow down www.pall.com/biopharm 5
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Page 7 and 8: Stax Chassis Information Table 11:

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Staxâ¢ Disposable Depth Filters - Pall Corporation (PLL)