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New psycho<strong>the</strong>rapy treats most eating disorders<br />

A new form <strong>of</strong> psycho<strong>the</strong>rapy American Journal <strong>of</strong> Psychiatry,<br />

has <strong>the</strong> potential to treat more Pr<strong>of</strong>essor Fairburn and his<br />

than eight out <strong>of</strong> ten cases <strong>of</strong> colleagues have now shown that<br />

eating disorders in adults, an CBT-E is not only more potent<br />

Oxford University-led study has than <strong>the</strong> earlier treatment, but it<br />

shown.<br />

can be used to treat both bulimia<br />

The eating disorders anorexia nervosa and <strong>the</strong> atypical eating<br />

nervosa and bulimia nervosa disorders. This makes it suitable<br />

are well known; <strong>the</strong> remainder for over 80% <strong>of</strong> cases <strong>of</strong> eating<br />

are classed as ‘atypical eating disorders.<br />

disorders’. All are a major cause Two versions <strong>of</strong> CBT-E were<br />

<strong>of</strong> physical and psychosocial compared in <strong>the</strong> study, which<br />

impairment in young women, treated 154 people via 20<br />

affecting at least one in twenty weekly 50-minute outpatient<br />

women between <strong>the</strong> ages <strong>of</strong> appointments. A simple version<br />

18 and 30. They also occur focused solely on <strong>the</strong> eating<br />

in young men but are less disorder and a second, more<br />

common.<br />

complex version simultaneously<br />

The new treatment, an addressed commonly<br />

‘enhanced’ form <strong>of</strong> cognitive associated problems such as<br />

behavioural <strong>the</strong>rapy (CBT-E), low self-esteem and extreme<br />

derives from an earlier form perfectionism.<br />

<strong>of</strong> CBT that was designed<br />

The researchers found that<br />

exclusively for patients with most patients responded<br />

bulimia nervosa. Both were well and rapidly to <strong>the</strong> two<br />

developed by Pr<strong>of</strong>essor<br />

forms <strong>of</strong> CBT-E and that <strong>the</strong><br />

Christopher Fairburn in <strong>the</strong> changes were sustained over<br />

<strong>Department</strong> <strong>of</strong> Psychiatry. <strong>the</strong> following year (<strong>the</strong> time at<br />

In a study published in <strong>the</strong> which relapse is most likely to<br />

Eating disorders affect around 5% <strong>of</strong> young women<br />

occur). Around two-thirds <strong>of</strong> to <strong>the</strong> more complex treatment<br />

those who completed treatment and vice versa.<br />

made a complete and lasting ‘Eating disorders are serious<br />

response with many <strong>of</strong> <strong>the</strong> mental health problems and<br />

remainder showing substantial can be very distressing for both<br />

improvement. Patients with patients and <strong>the</strong>ir families,’ says<br />

bulimia nervosa or an atypical Pr<strong>of</strong>essor Fairburn. ‘Now, for<br />

eating disorder responded <strong>the</strong> first time, we have a single<br />

equally well, though a planned treatment which can be effective<br />

sub-analysis showed that at treating <strong>the</strong> majority <strong>of</strong> cases<br />

patients with particularly complex without <strong>the</strong> need for patients to<br />

clinical features responded better be admitted into hospital.’<br />

iStockphoto/Aldo MurilloSdominick<br />

news<br />

Two malaria treatments for children show promise<br />

Clinical trials <strong>of</strong> a new malaria<br />

vaccine have shown it provides<br />

both infants and young children<br />

with substantial protection<br />

against malaria. The results are<br />

published in <strong>the</strong> New England<br />

Journal <strong>of</strong> Medicine.<br />

Studies <strong>of</strong> <strong>the</strong> RTS,S vaccine<br />

candidate developed by<br />

GlaxoSmithKline Biologicals<br />

were conducted in Kenya and<br />

Tanzania as part <strong>of</strong> a global<br />

effort led by The PATH Malaria<br />

Vaccine Initiative (MVI). Oxford<br />

University scientists led <strong>the</strong> work<br />

in Kilifi, Kenya.<br />

In children aged 5–17 months,<br />

<strong>the</strong> vaccine candidate was<br />

found to be 56% effective in<br />

preventing clinical disease.<br />

The findings support efforts<br />

to launch large-scale trials <strong>of</strong><br />

<strong>the</strong> vaccine starting in 2009<br />

across Africa.<br />

O<strong>the</strong>r research, reported in<br />

The Lancet, has shown that a<br />

simple treatment saves lives by<br />

buying <strong>the</strong> time necessary for<br />

children with severe malaria in<br />

rural areas <strong>of</strong> Asia and Africa to<br />

get to a clinic for full treatment.<br />

Pr<strong>of</strong>essor Nick White <strong>of</strong><br />

Oxford’s Centre for Tropical<br />

Medicine and <strong>the</strong> Faculty <strong>of</strong><br />

Tropical Medicine, Mahidol<br />

University, Thailand says:<br />

‘We’ve shown that children<br />

with severe malaria who are<br />

hours from a health clinic<br />

and are too ill to take <strong>the</strong>ir<br />

medicine by mouth can<br />

be given a single, simple<br />

suppository. This knocks down<br />

<strong>the</strong> malaria parasites in <strong>the</strong><br />

blood and buys life-saving time<br />

to get <strong>the</strong> children to a clinic<br />

for proper diagnosis and full<br />

treatment.’<br />

Blueprint January 2009 3

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