Beautiful Biochemistry Educating the workers - Department of ...
Beautiful Biochemistry Educating the workers - Department of ...
Beautiful Biochemistry Educating the workers - Department of ...
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New psycho<strong>the</strong>rapy treats most eating disorders<br />
A new form <strong>of</strong> psycho<strong>the</strong>rapy American Journal <strong>of</strong> Psychiatry,<br />
has <strong>the</strong> potential to treat more Pr<strong>of</strong>essor Fairburn and his<br />
than eight out <strong>of</strong> ten cases <strong>of</strong> colleagues have now shown that<br />
eating disorders in adults, an CBT-E is not only more potent<br />
Oxford University-led study has than <strong>the</strong> earlier treatment, but it<br />
shown.<br />
can be used to treat both bulimia<br />
The eating disorders anorexia nervosa and <strong>the</strong> atypical eating<br />
nervosa and bulimia nervosa disorders. This makes it suitable<br />
are well known; <strong>the</strong> remainder for over 80% <strong>of</strong> cases <strong>of</strong> eating<br />
are classed as ‘atypical eating disorders.<br />
disorders’. All are a major cause Two versions <strong>of</strong> CBT-E were<br />
<strong>of</strong> physical and psychosocial compared in <strong>the</strong> study, which<br />
impairment in young women, treated 154 people via 20<br />
affecting at least one in twenty weekly 50-minute outpatient<br />
women between <strong>the</strong> ages <strong>of</strong> appointments. A simple version<br />
18 and 30. They also occur focused solely on <strong>the</strong> eating<br />
in young men but are less disorder and a second, more<br />
common.<br />
complex version simultaneously<br />
The new treatment, an addressed commonly<br />
‘enhanced’ form <strong>of</strong> cognitive associated problems such as<br />
behavioural <strong>the</strong>rapy (CBT-E), low self-esteem and extreme<br />
derives from an earlier form perfectionism.<br />
<strong>of</strong> CBT that was designed<br />
The researchers found that<br />
exclusively for patients with most patients responded<br />
bulimia nervosa. Both were well and rapidly to <strong>the</strong> two<br />
developed by Pr<strong>of</strong>essor<br />
forms <strong>of</strong> CBT-E and that <strong>the</strong><br />
Christopher Fairburn in <strong>the</strong> changes were sustained over<br />
<strong>Department</strong> <strong>of</strong> Psychiatry. <strong>the</strong> following year (<strong>the</strong> time at<br />
In a study published in <strong>the</strong> which relapse is most likely to<br />
Eating disorders affect around 5% <strong>of</strong> young women<br />
occur). Around two-thirds <strong>of</strong> to <strong>the</strong> more complex treatment<br />
those who completed treatment and vice versa.<br />
made a complete and lasting ‘Eating disorders are serious<br />
response with many <strong>of</strong> <strong>the</strong> mental health problems and<br />
remainder showing substantial can be very distressing for both<br />
improvement. Patients with patients and <strong>the</strong>ir families,’ says<br />
bulimia nervosa or an atypical Pr<strong>of</strong>essor Fairburn. ‘Now, for<br />
eating disorder responded <strong>the</strong> first time, we have a single<br />
equally well, though a planned treatment which can be effective<br />
sub-analysis showed that at treating <strong>the</strong> majority <strong>of</strong> cases<br />
patients with particularly complex without <strong>the</strong> need for patients to<br />
clinical features responded better be admitted into hospital.’<br />
iStockphoto/Aldo MurilloSdominick<br />
news<br />
Two malaria treatments for children show promise<br />
Clinical trials <strong>of</strong> a new malaria<br />
vaccine have shown it provides<br />
both infants and young children<br />
with substantial protection<br />
against malaria. The results are<br />
published in <strong>the</strong> New England<br />
Journal <strong>of</strong> Medicine.<br />
Studies <strong>of</strong> <strong>the</strong> RTS,S vaccine<br />
candidate developed by<br />
GlaxoSmithKline Biologicals<br />
were conducted in Kenya and<br />
Tanzania as part <strong>of</strong> a global<br />
effort led by The PATH Malaria<br />
Vaccine Initiative (MVI). Oxford<br />
University scientists led <strong>the</strong> work<br />
in Kilifi, Kenya.<br />
In children aged 5–17 months,<br />
<strong>the</strong> vaccine candidate was<br />
found to be 56% effective in<br />
preventing clinical disease.<br />
The findings support efforts<br />
to launch large-scale trials <strong>of</strong><br />
<strong>the</strong> vaccine starting in 2009<br />
across Africa.<br />
O<strong>the</strong>r research, reported in<br />
The Lancet, has shown that a<br />
simple treatment saves lives by<br />
buying <strong>the</strong> time necessary for<br />
children with severe malaria in<br />
rural areas <strong>of</strong> Asia and Africa to<br />
get to a clinic for full treatment.<br />
Pr<strong>of</strong>essor Nick White <strong>of</strong><br />
Oxford’s Centre for Tropical<br />
Medicine and <strong>the</strong> Faculty <strong>of</strong><br />
Tropical Medicine, Mahidol<br />
University, Thailand says:<br />
‘We’ve shown that children<br />
with severe malaria who are<br />
hours from a health clinic<br />
and are too ill to take <strong>the</strong>ir<br />
medicine by mouth can<br />
be given a single, simple<br />
suppository. This knocks down<br />
<strong>the</strong> malaria parasites in <strong>the</strong><br />
blood and buys life-saving time<br />
to get <strong>the</strong> children to a clinic<br />
for proper diagnosis and full<br />
treatment.’<br />
Blueprint January 2009 3