Acute Kidney Injury in In Paediatrics

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Paediatric RIFLE (pRIFLE) • RIFLE modified for paediatric use • by normalizing SCr to body surface area (BSA) as an estimation of GFR, • with disease staging by a change in estimated SCr clearance (eCCl) from the patient’s baseline. • eCCl is calculated using Schwartz formula: Where k = 0.413 GFR = (k X Height)/ SCr
pRIFLE CLASS Change in eCCl Urine Output (by Schwartz) Risk Decrease by 25 % 3 months 12 hrs
Page 1 and 2: Acute Kidney Injury In Paediatrics
Page 3 and 4: What is AKI? • A sudden deteriora
Page 5 and 6: Long Term Outcomes • At 3 to 5-yr
Page 7: RIFLE vs AKIN
Page 11 and 12: Biomarkers • The pRIFLE, RIFLE an
Page 13 and 14: Biomarkers • The quest to find ea
Page 15 and 16: NGAL • Urine NGAL > 50ug/ml predi
Page 17 and 18: IL-18 • Induced in the proximal r
Page 19 and 20: Management • Prevention of AKI is
Page 21 and 22: Ways to Prevent Contrast-Induced Ne
Page 23 and 24: Ways to Prevent Contrast-Induced
Page 25 and 26: Common Nephrotoxins in ICU EXOGENOU
Page 27 and 28: Management General principles of
Page 29 and 30: Maintain Renal Perfusion Vasopresso
Page 31 and 32: Maintain Renal Perfusion • Renal
Page 33 and 34: Maintain Renal Perfusion Choice of
Page 35 and 36: Cumulative Fluid Overload • The p
Page 37 and 38: Nutritional Support • Nutrition i
Page 39 and 40: Renal Replacement Therapy • Curre
Page 41 and 42: Timing of RRT • In paediatrics, t
Page 43 and 44: Differences between adult and • P
Page 45 and 46: Differences between adult and • P
Page 47 and 48: With CRRT • We must continually w
Page 49 and 50: Conclusions • Management of AKI i
Page 51 and 52: Conclusion • However, paediatric

Acute Kidney Injury in In Paediatrics

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