HEFA-1999 Part 1/2nd proof - Human Fertilisation & Embryology ...

HUMAN FERTILISATION AND EMBRYOLOGY AUTHORITY
1999 ANNUAL REPORT & ACCOUNTS
Table 4.17 Developmental defects and syndromes
Chromosomal syndromes
Fresh Frozen Micro-
Total IVF IVF DI manipulation
Downs’ Syndrome 5 2 1 2
Other chromosomal abnomalites 3 1 2
Congenital abnormalities
Cleft lip 0
Cleft palate 4 1 1 0 1
Cleft lip with cleft palate 2 2
Tracheo-oesophageal fistula,
oesophageal atresia and stenosis 5 2 1 1 1
Atresia and Stenosis of the large
intestine, rectum and anal canal 7 2 1 4
Anomalies of the alimentary system 8 5 2 1
Cardiac murmurs 6 2 2 2
Ventricular septal defect 6 3 1 1 1
Other congenital cardiac anomalies 8 4 1 3
Other anomalies of the cardiac septa 2 1 1
Patent Ductus 2 1 1
Anomalies of the cardiovascular system 4 1 3
Hypospadias, Epispadias 3 1 1 1
Anomalies of the male external genetalia 2 1 1
Renal anomalies 10 1 1 1 7
Polydactyly or syndactyly 8 4 1 2 1
Reduction deformities of the limbs 4 2 1 1
Talipes 9 2 1 3 3
Congenital dislocation of the hip 3 1 1 1
Other anomalies of the limbs or
limb girdle 1 1
Anomalies of the nose, face,
neck and skull 3 2 1
Anomalies of the abdominal wall 4 1 1 2
Ear anomalies 3 2 1
Spina bifida 1 1
Exomphalos 2 1 1
Anomalies of the tongue, branchial cleft
and auricular sinus 2 1 1
Total number of children born 114 44 10 19 41
As a percentage of total number of
babies born as a result of each type
of licensed treatment 1.3 1.1 1.2 1.4 1.6
Note: Some children are born with more than one chromosomal or congenital abnormality.
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