Bone Marrow Pathology
Bone Marrow Pathology
Bone Marrow Pathology
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Other <strong>Marrow</strong> Cells<br />
Mast cells<br />
5-25 mm, elliptical or elongated<br />
Central nucleus, round or oval, nonlobated<br />
Numerous dark purple cytoplasmic granules<br />
Usually perivascular or near endosteum<br />
Osteoblasts<br />
20-50 mm, mesenchymal origin<br />
Responsible for bone deposition, usually in children<br />
Eccentric nucleus, small nucleous, basophilic cytoplasm<br />
Appear in rows along bony spicules<br />
Osteoclasts<br />
30-100 mm, multinucleated giant cells<br />
Separate, uniform nuclei, slightly oval, single nucleolus<br />
Voluminous cytoplasm, azurophilic granules<br />
Lie in hollows known as Howship’s lacunae
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