Dermal Sensitization QRA Approach for Fragrance Ingredient
Dermal Sensitization QRA Approach for Fragrance Ingredient
Dermal Sensitization QRA Approach for Fragrance Ingredient
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<strong>QRA</strong> DERMAL SENSITIZATION CINNAMIC<br />
ALDEHYDE IN SOLID AP - INDUCTION<br />
2.0 μg/cm<br />
2<br />
AEL<br />
0.02%<br />
1.7 μg/cm<br />
2<br />
CEL<br />
0.05%<br />
4.3 μg/cm<br />
2<br />
CEL<br />
590 μg/cm<br />
2<br />
WoE NESIL<br />
AEL/CEL Acceptable<br />
SAF = 300<br />
AEL/CEL<br />
Unacceptable<br />
0.001 0. 01 0.1 1.0 10 100 1000<br />
Cinnamic Aldehyde Level - log μg/cm<br />
2<br />
Api <strong>QRA</strong> Worksop Jan 2007
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