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Dermal Sensitization QRA Approach for Fragrance Ingredient

Dermal Sensitization QRA Approach for Fragrance Ingredient

Dermal Sensitization QRA Approach for Fragrance Ingredient

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RISK CHARACTERIZATION FOR<br />

FRAGRANCE INGREDIENTS<br />

• Acceptable Exposure Levels (AELs) to<br />

fragrance ingredients that are dermal<br />

sensitizers can be determined in specific real<br />

life consumer product types<br />

Acceptable<br />

Exposure Level (AEL) <strong>Sensitization</strong><br />

Assessment Factor<br />

(SAF)<br />

• Comparison of Acceptable Exposure Levels<br />

(AEL) to calculated Consumer Exposure<br />

Level (CEL)<br />

Api <strong>QRA</strong> Worksop Jan 2007<br />

=<br />

WoE NESIL<br />

AEL > CEL to be Acceptable

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