Dermal Sensitization QRA Approach for Fragrance Ingredient
Dermal Sensitization QRA Approach for Fragrance Ingredient
Dermal Sensitization QRA Approach for Fragrance Ingredient
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RISK CHARACTERIZATION FOR<br />
FRAGRANCE INGREDIENTS<br />
• Acceptable Exposure Levels (AELs) to<br />
fragrance ingredients that are dermal<br />
sensitizers can be determined in specific real<br />
life consumer product types<br />
Acceptable<br />
Exposure Level (AEL) <strong>Sensitization</strong><br />
Assessment Factor<br />
(SAF)<br />
• Comparison of Acceptable Exposure Levels<br />
(AEL) to calculated Consumer Exposure<br />
Level (CEL)<br />
Api <strong>QRA</strong> Worksop Jan 2007<br />
=<br />
WoE NESIL<br />
AEL > CEL to be Acceptable