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Jean-Jacques Garaud, MD Global Head Pharma ... - Roche

Jean-Jacques Garaud, MD Global Head Pharma ... - Roche

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Rheumatoid Arthritis: Not all patients respond to<br />

current therapy<br />

Gold standard therapy<br />

anti-TNF + MTX<br />

% ACR70 Responders<br />

Unmet Medical Need<br />

Only 1 of 3 patients receives<br />

significant benefit<br />

anti-TNF + MTX<br />

anti-TNF alone<br />

ACR 70=70% Improvement in:<br />

MTX alone<br />

Disease activity – patient<br />

Disease activity – physician<br />

Patient assessment of Pain<br />

Physical disability<br />

Acute phase reactants – CRP,ESR<br />

24

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