Jean-Jacques Garaud, MD Global Head Pharma ... - Roche
Jean-Jacques Garaud, MD Global Head Pharma ... - Roche
Jean-Jacques Garaud, MD Global Head Pharma ... - Roche
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Avastin in 2nd line mCRC: the only biologic with<br />
significant survival benefit<br />
Study Regimen OS<br />
Study arm<br />
Epic Irinotecan +/- Cetuximab<br />
OS<br />
control<br />
Benefit<br />
(detriment)<br />
ITT 10.71 9.99 0.7 0.98 0.712<br />
K-Ras WT 10.94 11.56 -0.6 1.28 na<br />
E 3200<br />
FOLFOX+/-Avastin<br />
ITT 12.9 10.8 2.1 0.75 0.001<br />
HR<br />
p<br />
36
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