CRITICAL CARE INTRAVENOUS MEDICATIONS CHART
CRITICAL CARE INTRAVENOUS MEDICATIONS CHART
CRITICAL CARE INTRAVENOUS MEDICATIONS CHART
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<strong>CRITICAL</strong> <strong>CARE</strong> <strong>INTRAVENOUS</strong> <strong>MEDICATIONS</strong> <strong>CHART</strong><br />
DRUG NAME ONSET CONCENTRATION UNIT OF MEASUREMENT DRUG CLASS HOW TO TITRATE<br />
Amiodarone<br />
Bumex<br />
(Bumetanide)<br />
Cardizem<br />
(Diltiazem)<br />
Cardene<br />
(Nicardipine)<br />
Cisatracurium<br />
(Nimbex)<br />
Corlopam<br />
(Fenoldopam)<br />
Dexmedetomdine<br />
(Precedex)<br />
Diprivan<br />
(Propofol)<br />
Dobutamine<br />
Dopamine<br />
Epinephrine<br />
Brevibloc<br />
(Esmolol)<br />
Fentanyl<br />
Furosemide<br />
(Lasix)<br />
Page 1<br />
Nonspecific<br />
2-3 min<br />
minutes<br />
10 min<br />
2-3 min<br />
10 min<br />
1 min<br />
seconds<br />
1-10<br />
min<br />
5 min<br />
minutes<br />
2-10<br />
min<br />
seconds<br />
5 min<br />
450mg / 250ml D5W only<br />
Can not mix in NS<br />
10mg / 100ml NS<br />
Can Mix in D5W<br />
100mg / 100 ml<br />
Can mix in NS and D5W<br />
20mg / 200ml<br />
40mg / 200ml<br />
Can mix in NS and D5W<br />
200mg / 200ml NS<br />
Can mix in D5W<br />
20mg/500ml<br />
Can mix in NS and D5W<br />
200mcg / 50ml<br />
Can mix in NS and D5W<br />
1000mg / 100 ml vial<br />
500mg / 50 ml vial<br />
Pre-Mixed<br />
500mg / 250ml (Standard)<br />
Can mix in NS and D5W<br />
400mg / 250ml (Standard)<br />
Can mix in NS and D5W<br />
5mg / 250ml (Standard)<br />
Can mix in NS and D5W<br />
2500 mg / 250 ml<br />
Pre-Mixed<br />
1mg / 100ml NS (Standard)<br />
Can mix in D5W<br />
100mg / 100 ml or 200 mg / 200 ml<br />
Can mix in NS and D5W<br />
Continuous Infusion – mg/min<br />
Common dose: 1mg / min for 6 hrs,<br />
then 0.5 mg /min infusion<br />
IV Bolus Dose – mg/hr<br />
Dose: 0.5 – 1 mg slow IVP over 1-2 min or<br />
Continuous Infusion – mg/hour<br />
Usual Dose: 1 mg/hr or (MD preference)<br />
Continuous Infusion – mg/hour<br />
Dose: 5 – 15 mg/ hr<br />
Titrate 5 mg/hr increments to desire effect<br />
Continuous Infusion – mg/hour<br />
Dose: 2.5 – 15 mg / hour<br />
Titrate 2.5 mg/hr increments Q 15 min<br />
Rotate IV infusion site Q 12 hr if given in<br />
periph. IV. If doubled need Central Line<br />
Continuous Infusion – mcg/kg/min<br />
May give IV loading dose: 0.1 mcg/kg<br />
Usual Range: 1 – 10 mcg/kg/min<br />
Titrate 2 mcg/kg/min increments<br />
Continuous Infusion – mcg/kg/min<br />
Dose: Initial 0.1 mcg/kg/min<br />
Avg. rate = 0.25 – 0.5 mcg/kg/min<br />
Loading dose = 1mcg / kg over 10 minutes<br />
Continuous Infusion - mcg/kg/hr<br />
Avg rate = 0.2 – 0.7 mcg/kg/hr<br />
Continuous Infusion – mcg/kg/min<br />
Dose: Usual range = 5-50 mcg/kg/min<br />
Continuous Infusion – mcg/kg/min<br />
Dose: 2 – 20 mcg/kg/min<br />
Continuous Infusion – mcg/kg/min<br />
Dose: 2 – 20 mcg/kg/min<br />
Continuous Infusion<br />
mcg/kg/minute -- OR -- mcg/min<br />
Usual Range: 1 – 10 mcg/min<br />
0.05 – 1 mcg/kg/min<br />
Continuous Infusion – mcg/kg/min<br />
Dose: Usual Range = 50-200 mcg/kg/min<br />
Continuous Infusion – mcg/hour<br />
Usual Range: 50 – 300 mcg/hr<br />
Titrate 25 mcg/hr increments<br />
IV Bolus Dose – mg<br />
Dose: 20 – 40 mg slow IVP over 1-2 min or<br />
Continuous Infusion - mg / hr<br />
Usual Dose: 10 - 20 mg/hr or (MD pref.)<br />
Antiarrhythmic<br />
Loop Diuretic<br />
Ca Channel<br />
Blocker<br />
Ca Channel<br />
Blocker<br />
Neuromuscular<br />
Blockade<br />
(Paralytic)<br />
Vasodilator<br />
Sedative<br />
(Alpha2 – Adrenergic<br />
Agonist)<br />
Conscious Sedation<br />
Vasopressor<br />
Vasopressor<br />
Vasopressor<br />
Cardiac Stimulant<br />
Antiarrhythmic /<br />
Beta Blocker<br />
Narcotic<br />
Analgesic<br />
Loop<br />
Diuretic<br />
Dose ordered per MD based on UOP or PCWP<br />
Increase rate 5 mg/hr<br />
Q 15 min to desired Heart Rate<br />
Start @ 5 mg/hr then increase rate 2.5 mg Q<br />
15 min. attempt to decrease to 3 mg/hr once<br />
B/P controlled<br />
Titrate to 2 - 4 twitches on Peripheral Nerve<br />
Stimulator (TOF) or per MD orders<br />
Titrate 0.05 – 0.1 mcg/kg/min increments Q15<br />
until target BP<br />
Titrate 0.1mcg/kg/hr Q10min<br />
Increments to desired level of Sedation<br />
(Max dose = 1.5 mcg/kg/hr)<br />
Increase 5 mcg/kg/min<br />
Q 5 minutes based on sedation (BIS or<br />
RASS)<br />
Increase rate 1 - 4 mcg/kg/hr Q 10 minutes<br />
Increase rate 1 - 4 mcg/kg/hr Q 10 minutes<br />
Increase 0.01 mcg/kg/min Q 15 minutes.<br />
Titrate to effect desired per MD<br />
Usual Titration: 50mcg/kg/min increments<br />
Increase rate 25 mcg/hr based on pain control<br />
Dose ordered per MD based on UOP and or<br />
PCWP
<strong>CRITICAL</strong> <strong>CARE</strong> <strong>INTRAVENOUS</strong> <strong>MEDICATIONS</strong> <strong>CHART</strong><br />
DRUG NAME ONSET CONCENTRATION UNIT OF MEASUREMENT DRUG CLASS HOW TO TITRATE<br />
Heparin<br />
seconds<br />
25,000 units / 250ml<br />
Continuous Infusion – units/hour<br />
Can mix in NS and D5W<br />
Dose: Weight-based --OR-- PTT-based<br />
Anticoagulant Based on PTT and Per Protocol per MD orders<br />
Insulin (regular) 30 min<br />
100 units / 100ml NS only<br />
Continuous Infusion – units/hour<br />
Based on Blood Glucose<br />
Hormone Agent<br />
Can not mix in D5W<br />
Dose: Based upon blood glucose level<br />
Per protocol per MD order<br />
Continuous Infusion<br />
Levophed<br />
4mg / 250ml (Standard)<br />
mcg/kg/minute -- OR -- mcg/min<br />
Increase rate 5 mcg /min<br />
seconds<br />
Vasopressor<br />
(Norepinephrine)<br />
Can mix in NS and D5W<br />
Usual Range: 0.5 – 30 mcg/min<br />
Q 3 – 5 minutes<br />
0.01 – 3 mcg/kg/min<br />
Continuous Infusion – mg/min<br />
Lidocaine<br />
2 mg/min = 15 ml/hr 4 mg = 30 ml/hr<br />
45-90 2 grams / 500ml (4mg/ml)<br />
Usual Range: 1 – 4 mg/min<br />
seconds Can mix in NS and D5W<br />
1mg/min = 7.5 ml/hr 3 mg/min = 22.5 ml/hr<br />
Antiarrhythmic<br />
Midazolam<br />
(Versed)<br />
Natrecor<br />
(Nesiritide)<br />
Neosynephrine<br />
(Phenylephrine)<br />
Nipride<br />
(Nitroprusside)<br />
Nitroglycerin<br />
Pavulon<br />
(Pancuronium)<br />
Primacor<br />
(Milrinone)<br />
Pronestyl<br />
Vasopressin<br />
Vecuron<br />
(Vecuronium)<br />
1-5 min<br />
15 min<br />
seconds<br />
< 2 min<br />
seconds<br />
2-3 min<br />
5-15<br />
min<br />
minutes<br />
minutes<br />
2-3 min<br />
125mg / 125 ml<br />
Can mix in NS and D5W<br />
1.5mg / 250ml = (6 mcg/ml)<br />
Can mix in NS and D5W<br />
20mg / 250ml (Standard)<br />
Can mix in NS and D5W<br />
50mg / 250ml D5W only, or 100mg<br />
/ 250ml D5W only<br />
Can not mix in NS<br />
25mg / 250ml (Standard)<br />
Can mix in NS and D5W<br />
50mg / 100 ml (Standard)<br />
Can mix in NS and D5W<br />
40mg / 200ml<br />
Can mix in NS and D5W<br />
2 grams / 250ml<br />
Can mix in NS and D5W<br />
20 units / 100ml (Standard)<br />
Can mix in NS and D5W<br />
20mg / 100ml (Standard)<br />
Can mix in NS and D5W<br />
Continuous Infusion – mg/hour<br />
Usual Range: 1 – 10 mg/hr<br />
Titrate 1 mg/hr increments<br />
IV bolus: 2 mcg/kg over 60 seconds<br />
Continuous Infusion: 0.01 mcg/kg/min<br />
Continuous Infusion – mcg/min<br />
Usual Range: 100 – 180 mcg/min<br />
Continuous Infusion – mcg/kg/min<br />
Dose: 0.3 –4 mcg/kg/min<br />
Titrate 0.5 mcg/kg/min increments<br />
Maximum = 10 mcg/kg/min<br />
Continuous Infusion – mcg/min<br />
Usual Range: 1 – 200 mcg/min<br />
Continuous Infusion – mg/kg/hr<br />
May give loading dose: 0.1 mg/kg slow IVP<br />
Usual Range: 0.02 – 0.1 mg/kg/hr<br />
Titrate: 0.02 mg/kg/hr increments<br />
Continuous Infusion – mcg/kg/min<br />
Usual Range: 0.375 – 0.75 mcg/kg/min<br />
Continuous Infusion – mg/min<br />
Usual Range: 1 – 4 mg / min<br />
1mg/min = 7.5 ml/hr 3 mg/min = 22.5 ml/hr<br />
2 mg/min = 15 ml/hr 4 mg/min = 30 ml/hr<br />
Continuous Infusion – units/min<br />
Range: 0.01 – 0.1 units/min<br />
Usual Dose: 0.04 units/min fixed dose OR<br />
Units / hr Usual Dose: 0.2 – 0.9 units / hr<br />
Continuous Infusion – mcg/kg/min<br />
May give loading dose: 100 mcg/kg IVP<br />
Usual Dose: 0.6 – 1.2 mcg/kg/min<br />
Titrate: 0.2 mcg/kg/min<br />
Benzodiazepine<br />
(Sedative)<br />
B N P Acutely<br />
Decompensated<br />
CHF<br />
Vasopressor<br />
Vasodilator<br />
Vasodilator<br />
Neuromuscular<br />
Blockade<br />
(Paralytic)<br />
+ Inotrope<br />
and Vasodilator<br />
Antiarrhythmic<br />
Vasopressor<br />
for Septic Shock<br />
and Tx GIB<br />
Neuromuscular<br />
Blockade<br />
(Paralytic)<br />
Increase rate 1 mg/hr based on sedation (titrate<br />
to lowest dose possible)<br />
If ordered, may be increased by 0.005 mcg/kg/<br />
min Q3hr (max = 0.03 mcg/kg/min)<br />
Increase rate 5 mcg/min<br />
Q 3 – 5 min.<br />
Increase rate 0.5 mcg/kg/min Q 3 – 5 min.<br />
Increase rate 5mcg/min<br />
Q 3-5 min. May increase 10mcg/min if<br />
exceeds 20<br />
Titrate to 2 – 4 twitches on Peripheral Nerve<br />
Stimulator<br />
(TOF) or MD order.<br />
Dose ordered per MD<br />
Increase rate in 0.2 – 0.5 units / hr. Q 15<br />
minutes Titrate to effect.<br />
Titrate to 2 – 4 twitches on Peripheral Nerve<br />
Stimulator<br />
(TOF) or MD orders<br />
Page 2<br />
Updated 5/09 KE/ MS /CW
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