Drug Eluting Balloons will Drug-Eluting Balloons ... - summitMD.com
Drug Eluting Balloons will Drug-Eluting Balloons ... - summitMD.com
Drug Eluting Balloons will Drug-Eluting Balloons ... - summitMD.com
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Vascular Healing Following PCB Use<br />
De Novo vs. ISR Applications<br />
Can we extrapolate the data gathered from ISR trials towards the<br />
development of DCB technologies aimed to treat de novo lesions?<br />
In-Stent Restenosis<br />
• Ballooning inside of a stent.<br />
• Quiescent disease state.<br />
• Mature neointima.<br />
De-Novo (+Stent)<br />
Emerging • Disrupting DCB a plaque.<br />
Trial Designs<br />
• Active disease state.<br />
DES<br />
Market<br />
• Presence of necrotic tissue.<br />
• Smaller degree of injury induced. • Higher degree of injury.<br />
• No additional material left behind.<br />
• Stent left behind.<br />
• Plaque drug uptake?<br />
• Best mechanism of delivery?<br />
• Pre, post, crimped stent?<br />
• Stent healing in vivo?<br />
ISR<br />
De Novo